Tincture of Vanilla.' by K

Total Page:16

File Type:pdf, Size:1020Kb

Tincture of Vanilla.' by K 706 JOURNAL OF THE Vol. IX,No. 7 menstruum of the tincture. As one of the objects of this research was to conserve alcohol it was particularly gratifying to note that a tincture made with a menstruum of 650 parts of alcohol and 350 parts of water produced a preparation that was all that could be desired both from a pharmaceutical and a therapeutic standpoint. The alkaloidal content was as required by the Pharmacopoeia. That this rnen- struum was sufficient to extract all the alkaloids of this drug was shown by the failure of the marc to give any reaction with Mayer's reagent after further extrac- tion. Depriving the drug of its oil in no way depreciates its activity, as the oil therefrom gave no evidence of containing any alkaloid. THE ANAKLYSISOF MERCURIAL OINTMENT." BY JOSEPH L. MAYER. The official method for the assay of Mercurial Ointment being too inaccurate and time consuming, I devised the following simpIer and more accurate procedure. Accurately weigh about 0.500 gramme of the ointment into a tared 100-Cc. beaker, warm gently; add about 50 Cc. of gasoline, stir with a glass rod to dissolve the fat, allow the mercury to subside, then carefully decant the liquid through a small filter paper and reject filtrate. Kow place funnel and filter paper over the beaker containing the mercury; add 10 Cc. nitric acid through the paper, employ- ing a pipette; wash with a small amount of water, and then place the beaker con- taining the mercury and nitric acid on a hot plate and heat gently until red fumes cease to be evolved ; wash the contents into a large Erlenmeyer flask, dilute to about 150 Cc. with water, add 2 Cc. ferric ammonium sulphate test solution and titrate with tenth-normal KCNS V. S. until the appearance of a permanent, yellowish- red color. Each Cc. of tenth-normal KCNS V. S. consumed corresponds to o.oroo3 gramme of mercury. Three assays made of a sample of blue ointment by this process yielded the following results: 30.034, 30.234 and 30.157 percent of mercury. The accuracy, simplicity, and rapidity of this method commend it for inclusion in the Pharmacopoeia. RESEARCHAND ANALYTICALLABORATORIES, OF THE LOUISK. LIGGETTCo. TINCTURE OF VANILLA.' BY K. A. BARTLETT. While tincture of vanilla is a preparation that has been in use for a great many years, there has never been a satisfactory official formula for it. At the time of the last revision of the U. S. P. the formula therein was not satisfactory. A new formula was devised and included in the N. F. IV. * Read before Scientific Section A. Ph. A., city of Washington meeting, 1920. Presented before Section on Practical Pharmacy and Dispensing, A. Ph. A,, City of Washington meeting, 1920. July 1920 AMERICAN PHARMACEUTICAL ASSOCIATION 707 This formula, however, instead of being an improvement, was decidedly a step in the wrong direction. It is troublesome enough on a small scale and as a manufacturing proposition it is almost impossible. One of the faults common to the formulae of both the U. S. P. VIII and the N..F. IV is the fact that they direct mixing the sugar with the cut vanilla beans and then direct percolation of this mixture. The N. F. IV in addition to this fault, unnecessarily complicates matters by first macerating the cut beans with straight alcohol. This alcohol is then filtered off and diluted with an equal volume of water, this mixture then being used as a menstruum for the final percolation. In order to bring out the fault with this manner of manipulation it may be well to refer back to the actual prepara- tion of these beans for market, where just prior to being tied into bundles and wrapped, they are given a thin coating of a fixed oil. This, together with the small amount of fixed oil that is naturally in the beans, readily explains why the above procedure is unsatisfactory. The initial maceration with straight alcohol dis- solves the fixed oil and then on diluting the percolate with water an unsightly mixture results, due to the throwing of this fixed oil out of solution. When this mixture is poured on the percolator, containing the very viscid mixture of sugar and cut vanilla beans, the percolator rapidly clogs and renders percolation so difficult that it is impractical. The following formula is submitted as one which has been in use for some time and one which gives very satisfactory results: Vanilla, cut in small pieces 100 Gm. Sugar, granular zoo Gm. Dilute alcohol, a sufficient quantity to make 1000 mils. Place the cut vanilla beans together with three hundred and twenty mils (320 mils) of dilute aicohol into a 1ooo.mil flask, preferably one with a wide mouth, and heat on a water bath under a reflux condenser for 6 hours, keeping the mixture nearly to the hoiliiig point, but not high enough to cause any loss of alcohol. Allow to cool and strain the liquid through cheese- cloth Then place the cut vanilla beans in a percolator, preparing the percolator as follows:- In the bottom place a piece of filter paper large enough to cover the bottom and extend a short way up the sides of the percolator. Thcn put in a layer of clean white sand, on top of that a layer of kicsclguhr and then an- other layer of sand. Pack alternately a layer of vanilla beans and a layer of kieselguhr. Pour on the strained liquid and percolate slowly, continuing percolation with diluted alco- hol. Mix the sugar with the percolate as fast as it is received and dissolve by agitation. Con- tinue percolation to obtain 1000 mils. The continuous heating of the beans with a portion of the menstruum greatly facilitates extraction. There is no unsightly and troublesome precipitation of fixed oil and percolation is easy. Anyone who has had experience with tincture of vanilla knows the difficulties attending its filtration and to overcome this I strongly recommend that a percola- tor prepared in the above described manner be used. Any excess of oil which may be extracted from the drug is immediately removed by the kieselguhr and sand, and the percolate conies brilliantly clear. If a good quality, clean sugar be used, fil- tration will be unnecessary. In manufacturing the preparation on a larger scale the cut vanilla beans and 708 JOURNAL OF THE Vol. IX, No. 7 diluted alcohol may be placed in a clean still of suitable capacity, the lid tightly clamped down and then the mixture heated for the specified length of time. The advantages of this formula over the present one are many, and I strongly recommend its adoption toareplace the formula now official. LABORATORIBS OF E. R. SQUIRB& SONS, BROOKLYN,N. Y. ISO-ALCOHOLIC ELIXIRS. BY BBRNARD FANTUS.* Aromatic elixir, which is intended to serve as a vehic,s for alcc,,olic prepara- tions and alcohol-soluble medicaments, falls short of its purpose by reason of its fixed alcohol content, which makes it suitable as a diluent only for hydro-alcoholic tinctures of rather low alcohol percentage, and as a vehicle for drugs that do not require strong alcohol for solution. This difficulty may, of course, easily be over- come by fortifying the elixir with alcohol, so as to give it the alcoholic strength required. It is, however, practically impossible for the prescribing physician to carry in his mind the alcoholic strength of the various menstrua used in the extrac- tion of the drugs he employs, and it is not always possible for him to consult a reference book. The pharmacist, on the other hand, could easily adjust, with the aid of his official books, the proportion of alcohol in the elixir, so as to make it compatible with the medicament it is to carry. Indeed, this ought to be required of the pharmacist by making the aromatic elixir of the Pharmacopoeia “iso-alco- holic,” i. e., of an alcoholic strength adjustable to the requirements of the medica- ment for which it is to serve as a vehicle. This would not make it necessary for the druggist to carry in stock elixirs of varying alcoholic strengths; as he could easily, by means of a table, adjust the strength of a standard elixir to the alcohol percentage demanded. With this in view, it might be well to reduce the alcoholic strength of aromatic Elixir to five per- cent, which is that of some of the “aqueous” elixirs of the National Formulary, such as the Compound Elixir of Almond, and the Aqueous Elixir of Glycyrrhiza. This reduction would have several advantages. The “aqueous” elixir would be much less likely to be sought after as an alcoholic beverage. Furthermore, it would reduce the expense of quite a number of preparations, such as the bromide elixirs and many other elixir solutions of water-soluble chemicals of the N. F., the alcohol contents o€ which are at present decidedly excessive. The following modification of the official formula for aromatic elixir might therefore be proposed: AROMATIC ELIXIR. Compound Spirit of Orange.. ......................... 10 mils Syrup .............................................. 375 mils Purified Talc ........................................ 30 Gm. Alcohol ............................................. somils Distilled Water, a sufficient quantity to make.. ......... 1000 mils Mix the compound spirit of orange with the alcohol. To this solution add the syrup in several portions, agitating after each addition, atid afterwards add in the same manner 560 mils * Associate Professor of Therapeutics, Rush Medical College. .
Recommended publications
  • Extracts and Tinctures of Cannabis
    WHO Expert Committee on Drug Dependence Critical Review …………….. Extracts and tinctures of cannabis This report contains the views of an international group of experts, and does not necessarily represent the decisions or the stated policy of the World Health Organization © World Health Organization 2018 All rights reserved. This is an advance copy distributed to the participants of the 41st Expert Committee on Drug Dependence, before it has been formally published by the World Health Organization. The document may not be reviewed, abstracted, quoted, reproduced, transmitted, distributed, translated or adapted, in part or in whole, in any form or by any means without the permission of the World Health Organization. The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters. The World Health Organization does not warrant that the information contained in this publication is complete and correct and shall not be liable for any damages incurred as a result of its use.
    [Show full text]
  • Thinning Hair and Hair Loss
    Thinning Hair and Hair Loss Background: Hair loss, thinning hair and poor general hair health effects a very large number of people and these problems typically begin to manifest past the age of 40. However, the primary cause of hair loss is not age but a complex interaction between dozens of variables that include hormone imbalances, vitamin and mineral deficiencies, inflammation, free radical damage, poor diet, stress and poor sleep. However, when it comes to supporting hair health to encourage optimal hair growth, there is much that can be done. The key point is that hair loss is normal; the average adult has around 150,000 hairs on their head and loses around 100 of these a day. This is a normal process to allow new healthy hair to re-grow. Thus hair loss only becomes an issue if we lose more hair than we are able to replace. Thus when intervening to address thinning hair or hair loss, the priority is to ensure that the body is receiving all of the nutritional support needed to facilitate optimal hair growth whilst turning to specific herbal medicines to actually speed up the re-growth of new hair. Management Plan for Treating Hair Loss and Thinning Hair 1. Hair Supporting Herbal Tincture: There are many evidence based herbs that have been shown to effectively support general hair health whilst encouraging the growth of new hair. Interestingly, many of these herbs come from within the Ayurvedic system of medicine. When using herbal medicine to address hair loss, it is also really important to target and support liver function which plays an integral role in the breakdown and delivery of nutrients to the hair.
    [Show full text]
  • 2021 SELECT EX FORMULARY the Following Is a List of the Most Commonly Prescribed Brand and Generic Medications
    2021 SELECT EX FORMULARY The following is a list of the most commonly prescribed brand and generic medications. It represents an abbreviated version of the formulary list that is at the core of your prescription drug benefit plan. The list is not all-inclusive and does not guarantee coverage. Some preferred medications overlap with other clinical programs and may not be covered. In addition to drugs on this list, the majority of generic medications are covered under your plan and you are encouraged to ask your doctor to prescribe generic drugs whenever appropriate. Search complete formulary drug information at elixirsolutions.com. PLEASE NOTE: Preferred brand drugs may move to non-preferred status if a generic version becomes available during the year. Any medication approved to enter the market will not be covered until reviewed by Elixir. Not all drugs listed are covered by all prescription drug benefit programs. For specific questions about your coverage, please visit elixirsolutions.com. A B CILOXAN OINTMENT digoxin abacavir tablet balsalazide CIMDUO diltiazem ER (except generics for abacavir-lamivudine BAQSIMI cinacalcet CARDIZEM LA) ABILIFY MAINTENA [INJ] BASAGLAR [INJ] ciprofloxacin dimethyl fumarate DR* abiraterone* BD ULTRAFINE INSULIN SYRINGES ciprofloxacin-dexamethasone diphenoxylate-atropine acetic acid & NEEDLES citalopram dipyridamole ER-aspirin acitretin BELBUCA CITRANATAL divalproex sodium ACUVAIL BELSOMRA clarithromycin divalproex sodium ER acyclovir capsule, tablet benzonatate (except NDCs: clarithromycin ER DIVIGEL
    [Show full text]
  • Grow Your Own Herbal Remedies
    Grow Your Own Herbal Remedies: How to Create a Customized Herb Garden to Immune and Respiratory Support Your Health and Well-Being Immune SOS Elder, Echinacea, Bee Balm, Garlic By Maria Noël Groves Recipes: Darcey Blue’s Elderberry Syrup, Elder-Rosehip Oxymel, Echinacea Root Tincture, Bee Balm Honey, Bee Balm-Mint Tea REMEDY GARDENS OVERVIEW Daily Tonics Lung Tonics Nutritive Garden Mullein, Horehound, Wild Cherry, Marshmallow, Plantain Nettle, Oat Straw, Calendula, Violet, Rosehips Recipes: Soothing Lung Tea, Horehound Cough Syrup, Raw Wild Recipes: Nettle Oat Super Infusion, Chai Base, Nutri-Tea, Nutri- Cherry Honey Broth Allergy and Sinus Nutritive Forager Nettle, Goldenrod, Horehound, Bee Balm, Goldenseal and Berberines Nettle, Dandelion, Burdock, Horsetail, Violet Recipes: Allergy Tincture Blend, Nettle-Peppermint-Marshmallow Recipes: Multimineral Vinegar, Mineral-Rich “Coffee” Syrup, Tea Dandelion Violet Weed Pesto Skin Care and First Aid The Flavor Garden Super Skin Korean Mint and Anise Hyssop, Lemongrass and Lemon Verbena, Calendula, Rose, Lavender, Gotu Kola, Comfrey Mint, Calendula Recipes: Calendula Oil, Rose Hydrosol, Comfrey Root Liniment, Tea Base Notes: Nettle, Marshmallow, Oat Straw, Violet, Raspberry, Calendula Comfrey Cream Lady’s Mantle, Lemon Balm Recipes: Yummy Teas, Tea Base Notes, Floral Ice Cubes, Seltzer, First Aid Soda, and Infused Water Plantain, Yarrow, Calendula, St. John’s Wort, Thuja Recipes: Super Skin Salve, Ick Stick Thuja Salve, First Aid Simples Energy and Relaxation Stress Support Insect Repellent and Bite Care Holy Basil, Gotu Kola, Ashwagandha, Milky Oat Seed, Roses Lavender, Yarrow, Plantain, Catnip Recipes: Milky Oats Tincture, Stress Support Tincture Blend, Holy Recipes: Herbal Insect Repellent, Plantain Poultice, Plantain-Yarrow Rose Water, Ashwagandha Milk Bite Rub, Poison Ivy Relief Tips Brain Boosters Pain RelieF Gotu Kola, Bacopa, Rosemary, Lemon Balm, Mint Topical Pain RelieF Recipes: Brain Boosting Tincture Blend, Brainiac Bonbons, Minty Meadowsweet and Birch, St.
    [Show full text]
  • Safety Data Sheet According to 29CFR1910/1200 and GHS Rev
    Safety Data Sheet according to 29CFR1910/1200 and GHS Rev. 3 Effective date : 12.16.2014 Page 1 of 7 Iodine, Tincture, ~2% Solution SECTION 1: Identification of the substance/mixture and of the supplier Product name: Iodine, Tincture, ~2% Solution Manufacturer/Supplier Trade name: Manufacturer/Supplier Article number: S25944 Recommended uses of the product and restrictions on use: Manufacturer Details: AquaPhoenix Scientific, Inc 9 Barnhart Drive Hanover, PA 17331 (717) 632-1291 Supplier Details: Fisher Science Education 6771 Silver Crest Road, Nazareth, PA 18064 (724)517-1954 Emergency telephone number: Fisher Science Education Emergency Telephone No.: 800-535-5053 SECTION 2: Hazards identification Classification of the substance or mixture: Irritant Skin irritation, category 2 Eye irritation, category 2A Flammable Flammable liquids, category 2 Skin Irritation, Category 2. Eye Irritation, Category 2. Flam. Liq. 2. Signal word: Danger Hazard statements: Extremely flammable liquid and vapour. Causes serious eye irritation. Causes skin irritation. Precautionary statements: If medical advice is needed, have product container or label at hand. Keep out of reach of children. Read label before use. Wash skin thoroughly after handling. Wear protective gloves/protective clothing/eye protection/face protection. Keep away from heat/sparks/open flames/hot surfaces. No smoking. Keep container tightly closed. Ground/bond container and receiving equipment. Created by Global Safety Management, 1-813-435-5161 - www.GSMSDS.com Safety Data Sheet according to 29CFR1910/1200 and GHS Rev. 3 Effective date : 12.16.2014 Page 2 of 7 Iodine, Tincture, ~2% Solution Use explosion-proof electrical/ventilating/light/…/equipment. Use only non-sparking tools. Take precautionary measures against static discharge.
    [Show full text]
  • A Concise Guide to Treating Painful Oral Lesions
    Drugs Used to Treat Osteoporosis and Bone Cancer Perio & Implant Centers The Team for of the Monterey Bay (831) 648-8800 Jochen P. Pechak, DDS, MSD in Silicon Valley (408) 738-3423 Which May Cause Osteonecrosis of the Jaws mobile: www.DrPechakapp.com he many bisphosphonates and monoclonal antibodies which are used to treat osteoporosis and bone cancer often web: GumsRus.com causeDrugsDrugs osteonecrosis Used Used of the to jaws.to Treat AsTreat dental clinicians,Osteoporosis Osteoporosis it is important that and andwe are Bone awareBone of this Cancers Cancers side effect before Ttreating our patients who are taking these drugs. The tables below summarize these drugs, the route these drugs are administered, andWhich Whichtheir likelihood May May of causing Cause Cause osteonecrosis Osteonecrosis Osteonecrosis of the jaws as reported byof of Dr. the theRobert Jaws JawsMarx at the University of Miami Division of Oral and Maxillofacial Surgery. PDL tm Osteoporosis Drugs Drugs Osteoporosis Used to Treat Drugs Osteoporosis PerioDontaLetter Jochen P. Pechak, DDS, MSD, Periodontics and Implant Dentistry Spring DrugDrug ClassificationClassification ActionAction DoseDose RouteRoute %% of of ReportedReported CasesCases of of OsteonecrosisOsteonecrosis AlendronateAlendronate BisphosphonateBisphosphonate OsteoclastOsteoclast 7070 mg/wk mg/wk OralOral 8282%% From Our Office A Concise Guide to Treating (Fosamax(Fosamax ToxicityToxicity to Yours... Generic)Generic) Painful Oral Lesions ResidronateResidronate BisphosphonateBisphosphonate OsteoclastOsteoclast 3535 mg/wk mg/wk OralOral 1%1% As dentists specializing in treat- (Actonel Toxicity (Actonel Toxicity ment of diseases of the oral cavity atients present frequently with Treating Cold Sores Atelvia)Atelvia) and associated structures, we are painful oral lesions. They are often also called upon to treat pain- IbandronateIbandronate BisphosphonateBisphosphonate OsteoclastOsteoclast 150150 mg/mos mg/mos OralOral 1%1% usually not serious, but patients And Canker Sores (Boniva) Toxicity IV ful oral lesions in the mouth.
    [Show full text]
  • Making an Elderberry Syrup Or Elixir
    Making an Elderberry Syrup or Elixir Herbal syrups are water extractions of herbs (usually decoctions—see below) that are concentrated with a sweetener (preferably organic white sugar or raw honey). This sweetener provides a bit of nutritional support as a carbohydrate and also acts as a preservative. The concentration of sugar is particularly important when making syrups and elixirs; when in water, sugar acts as a food source for micro-organisms (especially molds and yeasts). However, at a high enough concentration, the sugar actually restricts the growth ability of micro-organisms. So we are aiming to get our syrup to be saturated enough to preserve, but not so saturated that the sugar overwhelms the liquid and causes crystallization. When preparing a syrup, one of the following ratios should be used: 1 part decoction : 1 part sweetener 1 part decoction : 2 parts sweetener I tend to follow the 1 part water : 1 part sweetener suggestion, as the 1 : 2 ratio is too sweet for me. But I have access to a refrigerator, which will also help with preservation. If you are keeping your syrup at room temperature, the 1:2 ratio is best. Syrups are a great, palatable method for delivery of herbal medicines (especially for children), and are also a great way to mask the flavor of less tasty tinctures--just combine the tincture and the syrup and you get the medicinal benefits of both. Preserving syrups with honey is also a great way to combine the medicinal benefits of the honey with the herbs that are being used. Do not give syrups preserved with honey to children under the age of one.
    [Show full text]
  • Medical Cannabis Tinctures Are Still Popular Among to Be Absorbed Into Patients, Especially Those Who Need to Take Regular the Body Efficiently
    TerrAscend NJ developed a proprietary line of medical cannabis formulations to help patients manage Four Universal Symptoms. Pain Anxiety Sleeplessness Lack of Energy/Focus MEDICAL FORMULATIONS SHINE 1:1 THC/CBD Ratio EASE SATIVA TERPENES SATIVA 1:10 THC/CBD Ratio BREATHE UPLIFTING HOW DO TINCTURES WORK? 2:1 THC/CBD Ratio Most tinctures are taken by placing drops under the HOPE 1 tongue and holding in the mouth for a few seconds, 1:1 THC/CBD Ratio also known as sublingual administration. When you take a tincture sublingually, the cannabinoids are TERPENES FREEDOM absorbed by the blood vessels lining the mouth, 1:1 THC/CBD Ratio resulting in a quick onset of effects. HYBRID Tinctures can be felt as quickly as 15 to 30 minutes after dosing sublingually. Peak effects usually occur HOPE 2 around 90 minutes after consumption and can last 3 5:1 THC/CBD Ratio to 6 hours, depending on the dose. BALANCED SOOTHE Tinctures can also be ingested orally, such as by 5:1 THC/CBD Ratio swallowing. If you consume a tincture orally, the cannabinoids are absorbed through the stomach and gastrointestinal tract and take longer to enter the DREAM bloodstream. 8:1 THC/CBD Ratio Dosing a tincture is easy to control because of the INDICA TERPENES precise measurements on the dropper. A patient can consume a small amount, wait for the effects and THC+ take more if necessary. Full Strength THC No Additives or Flavoring SEDATING As with any form of medical cannabis, you should start with a small dose to gauge how it makes you Products are not intended to diagnose, treat, cure or prevent feel and to avoid the unwanted effects of over- any disease.
    [Show full text]
  • Slang Terms and Jargon Can Cause Medication Errors
    Volume 19, Number 10 November/December 2005 Drugs & Therapy B � U � L � L � E � T � I � N MEDICATION SAFETY FORMULARY UPDATE The Pharmacy and Therapeutics Slang terms and jargon can Committee met October 18, 2005. 4 products were added in the Formulary cause medication errors and 2 were deleted. 1 dosage form was evaluated and designated nonformu- his month “Magic Mouthwash” ents. An allergy screen would not be lary and not available, and 2 drugs T was deleted from the Formulary done, unless the individual ingredients were evaluated, but not added. Criteria (see Formulary Update). The P&T are appreciated. for use were modifi ed for 3 drugs. Committee took this action for medica- Magic Mouthwash will no longer be tion safety reasons. This continues the dispensed at Shands UF because there ◆ ADDED policy of not allowing the use of non- is no evidence that it works better than specifi c terms for mixtures that have a plain saline rinse. Clozapine Tablets traditionally been used. This action follows the banning of (generic by IVAX) Terms like “Magic Mouthwash” are the term “Butt Paste” several years Glutaraldehyde 0.6% Solution slang, jargon, or coined phrases for ago. Like Magic Mouthwash, Butt Paste (compounded) mixtures that have a specifi c purpose. is a nonspecifi c mixture of ingredients. Levofl oxacin In this instance, the “magic” is pain The “Butt Paste” mixture contained (Levaquin® by Ortho McNeil)* reduction in patients who have muco- Questran Light® (cholestyramine) in sitis of the mouth. Mucositis is a very Aquaphor®. The theory is that the cho- Ondansetron Tablets ® painful condition in patients receiving lestyramine binds bile acids that may (Zofran by GlaxoSmithKline) aggressive cytotoxic chemotherapy.
    [Show full text]
  • Pharmacy Manual Supplemental Policies, Procedures and Regulations
    Last revision date: 12.17.2020 Pharmacy Manual Supplemental Policies, Procedures and Regulations Prepared by: Elixir 800-361-4542 ELIXIRSOLUTIONS.COM 2181 E. Aurora Road, Suite 201 | Twinsburg, OH 44087 Copyright © 2020, Elixir. All rights reserved. Version 41 *This page was intentionally left blank* 1 Table of Contents PHARMACY MANUAL INTRODUCTION......................................................................................................................... 5 GENERAL INFORMATION ............................................................................................................................................. 5 PROPRIETARY AND CONFIDENTIAL .................................................................................................................. 5 ADVERTISING REQUESTS .............................................................................................................................. 6 CONTACT INFORMATION / WHERE TO GET HELP ...................................................................................................... 6 NETWORK ENROLLMENT FORM AND CREDENTIALING GUIDELINES ....................................................................... 6 APPLYING FOR PARTICIPATION ...................................................................................................................... 6 CREDENTIALING AND RECREDENTIALING GUIDELINES ....................................................................................... 7 PROVIDER AND MEMBER SERVICE STANDARDS .....................................................................................................
    [Show full text]
  • Epinephrine Auto-Injector
    ELIXIR; Epinephrine Auto-Injector FINAL DESIGN & PRODUCT SPECIFICATION REPORT DNH603_SEM2 Zoe Avgoustakis n8607912 CONTENTS 1. Introduction 2. Final Product Design 2.1 Description 2.2 Usability 2.3 QoI Table / Product Ecosystem 3. Value Proposition , 4. Design Justification 4.1 Mechanism 4.2 Form 4.3 Usability 5. Technical Documentation 5.1 Product Components 5.2 Product Function 5.3 Specifications 5.4 Standards 5.5 B.O.M Technical Drawings DNH603_16se2 : i-move project Epinephrine Auto-injector Zoe Avgoustakis n8607923 0.03mg Adrenaline 1. INTRODUCTION Over the course of this project, imm-you-nity has worked to provide innovative design solutions focused on interactive interfaces and devices to help people be more aware, in control and engaged with their health and wellness. The project aim was to design and develop a new consumer interactive product that would provide a distinct personal experience, improving the user’s management and relationship with their Health & Wellness. The project was specifically focused towards the user’s engagement with allergy conditions. Design investigation accounted for emerging technologies and how this could be applied to enhance the user’s management and interaction with severe allergies and anaphylaxis. Australia has one of the highest reported incidences of food allergies in the world with one in ten people forecasted to develop a food allergy throughout their lives. As those who obtain allergies become more and more prevalent, people are turning to technology for assitance of this issue. The client approached the team in endeavour to develop a product that could assist people with the management and treatment of severe allergy conditions of anaphylaxis.
    [Show full text]
  • 2020 PBD 5 Tier Formulary
    2020 Pharmacy Benefit Dimensions 5 Tier Drug Formulary The following information applies to most members enrolled in a Pharmacy Benefit Dimensions pharmacy plan. Note: If you are reading a printed version of this drug formulary, content may have been updated since it was last printed. For the most up-to-date information, please visit www.pbdrx.com. Drug Formulary Introduction • Generic drugs appear in lower case. Brand name drugs are capitalized. • Preferred generic drugs and a few select brand name drugs are assigned to Tier 1. In most instances, once a generic product is available for which there are no bioequivalence concerns, the brand product is removed from the formulary (not covered), and the generic product is assigned to Tier 1. Certain generic drugs may also be covered in a non-preferred tier when efficacy, safety, or cost factors suggest that better alternatives exist on the formulary. • Pharmacy Benefit Dimensions reserves the right to modify drug tiers as necessary. • Some medications are considered non-formulary (not covered). To obtain a medication that is non-formulary, your health care provider is encouraged to submit a Prior Authorization request for coverage through the exception process. If the request is approved, you will be responsible for the cost share associated with a non- preferred drug tier. • Certain self-funded employer groups may not follow this base formulary and certain exclusions may apply. Members in these pharmacy benefit management groups should refer to their summary plan description and/or their benefit administrator. Prior-Authorization Prior Authorization is required for certain medications. To obtain coverage for a medication requiring Prior Authorization, a Prior Authorization request for medical exception must be submitted by your health care provider and approved by Pharmacy Benefit Dimensions.
    [Show full text]