Federal Register/Vol. 85, No. 47/Tuesday, March 10, 2020

Total Page:16

File Type:pdf, Size:1020Kb

Federal Register/Vol. 85, No. 47/Tuesday, March 10, 2020 14098 Federal Register / Vol. 85, No. 47 / Tuesday, March 10, 2020 / Proposed Rules ENVIRONMENTAL PROTECTION • Federal eRulemaking Portal: making effective comments, please visit AGENCY https://www.regulations.gov/ (our https://www.epa.gov/dockets/ preferred method). Follow the online commenting-epa-dockets. 40 CFR Part 141 instructions for submitting comments. When submitting comments, • Mail: Water Docket, Environmental remember to: [EPA–HQ–OW–2019–0583; FRL–10005–88– Protection Agency, Mail Code: [28221T], • Identify the rulemaking by docket OW] 1200 Pennsylvania Ave. NW, number and other identifying Announcement of Preliminary Washington, DC 20460. information (subject heading, Federal • Hand Delivery: EPA Docket Center, Regulatory Determinations for Register date, and page number). [EPA/DC] EPA West, Room 3334, 1301 • Contaminants on the Fourth Drinking Explain why you agree or disagree Constitution Ave. NW, Washington, DC. Water Contaminant Candidate List and suggest alternatives. Such deliveries are only accepted • Describe any assumptions and AGENCY: Environmental Protection during the Docket’s normal hours of provide any technical information and/ Agency (EPA). operation, and special arrangements or data that you used. • ACTION: Request for public comment. should be made for deliveries of boxed Provide specific examples to information. illustrate your concerns and suggest SUMMARY: The Safe Drinking Water Act Instructions: All submissions received alternatives. (SDWA), as amended in 1996, requires must include the Docket ID No. for this • Explain your views as clearly as the Environmental Protection Agency rulemaking. Comments received may be possible. (EPA) to make regulatory posted without change to https:// • Make sure to submit your determinations every five years on at www.regulations.gov/, including any comments by the comment period least five unregulated contaminants. A personal information provided. For deadline identified. regulatory determination is a decision detailed instructions on sending B. Does this action apply to me? about whether or not to begin the comments and additional information process to propose and promulgate a on the rulemaking process, see the Neither these preliminary regulatory national primary drinking water ‘‘Written Comments’’ heading of the determinations nor the final regulatory regulation (NPDWR) for an unregulated SUPPLEMENTARY INFORMATION section of determinations, when published, contaminant. A preliminary regulatory this document. impose any requirements on anyone. determination lays out and takes FOR FURTHER INFORMATION CONTACT: Instead, this action notifies interested comment on EPA’s view about whether Richard Weisman, Standards and Risk parties of the EPA’s preliminary certain unregulated contaminants meet Management Division, Office of Ground regulatory determinations for eight three statutory criteria. After EPA Water and Drinking Water, MC: 4607M, unregulated contaminants for comment. considers public comment, EPA makes Environmental Protection Agency, 1200 Abbreviations Used in This Document a final determination. The unregulated Pennsylvania Ave. NW; telephone contaminants included in a regulatory number: (202) 564–2822; email address: Abbreviation Meaning determination are chosen from the [email protected]. ADAF .............. Age Dependent Adjustment Fac- Contaminant Candidate List (CCL), SUPPLEMENTARY INFORMATION: tor which the SDWA requires the EPA to ADONA ........... 4,8-dioxa-3H-perfluorononanoic publish every five years. The EPA I. General Information acid ALT ................. Alanine Aminotransferase published the fourth CCL (CCL 4) in the A. Written Comments AM .................. Assessment Monitoring Federal Register on November 17, 2016. Submit your comments, identified by AOP ................. Advanced Oxidative Process This document presents the preliminary ASDWA .......... Association of State Drinking Docket ID No. EPA–HQ–OW–2019– Water Administrators regulatory determinations and 0583, at https://www.regulations.gov supporting rationale for the following ATSDR ............ Agency for Toxic Substances and (our preferred method), or the other Disease Registry eight of the 109 contaminants listed on methods identified in the ADDRESSES AWIA .............. America’s Water Infrastructure CCL 4: Perfluorooctanesulfonic acid Act section. Once submitted, comments BAT ................. Best Available Technology (PFOS), perfluorooctanoic acid (PFOA), cannot be edited or removed from the 1,1-dichloroethane, acetochlor, methyl BMD ................ Benchmark Dose docket. The EPA may publish any BMDL .............. Benchmark Dose Level bromide (bromomethane), metolachlor, comment received to its public docket. BMDS .............. Benchmark Dose Software nitrobenzene, and Royal Demolition BMR ................ Benchmark Response Do not submit electronically any BW .................. Body Weight eXplosive (RDX). The Agency is making information you consider to be preliminary determinations to regulate CAR ................. Constitutive Androstane Recep- Confidential Business Information (CBI) tor two contaminants (i.e., PFOS and or other information whose disclosure is CBI .................. Confidential Business Informa- PFOA) and to not regulate six tion restricted by statute. Multimedia CCL ................. Contaminant Candidate List contaminants (i.e., 1,1-dichloroethane, submissions (audio, video, etc.) must be acetochlor, methyl bromide, CCL 1 .............. First Contaminant Candidate List accompanied by a written comment. CCL 2 .............. Second Contaminant Candidate metolachlor, nitrobenzene, and RDX). The written comment is considered the List The EPA seeks comment on these CCL 3 .............. Third Contaminant Candidate official comment and should include List preliminary determinations. The EPA is discussion of all points you wish to also presenting an update on three other CCL 4 .............. Fourth Contaminant Candidate make. The EPA will generally not List CCL 4 contaminants (strontium, 1,4- consider comments or comment CDPHE ............ Colorado Department of Public dioxane, and 1,2,3-trichloropropane). Health and Environment contents located outside of the primary CDR ................. Chemical Data Reporting DATES: Comments must be received on submission (i.e., on the web, cloud, or CIIT ................. Chemical Industry Institute of or before May 11, 2020. other file sharing system). For Toxicology ADDRESSES: You may send comments, additional submission methods, the full CNS ................. Central Nervous System cPAD ............... Chronic Population Adjusted identified by Docket ID No. EPA–HQ– EPA public comment policy, Dose OW–2019–0583, by any of the following information about CBI or multimedia CRL ................. Cancer Risk Level methods: submissions, and general guidance on CSF .................. Cancer Slope Factor VerDate Sep<11>2014 18:18 Mar 09, 2020 Jkt 250001 PO 00000 Frm 00002 Fmt 4701 Sfmt 4702 E:\FR\FM\10MRP4.SGM 10MRP4 khammond on DSKJM1Z7X2PROD with PROPOSALS4 Federal Register / Vol. 85, No. 47 / Tuesday, March 10, 2020 / Proposed Rules 14099 Abbreviation Meaning Abbreviation Meaning Abbreviation Meaning CWS ................ Community Water System NPYR .............. N-Nitrosopyrrolidine WQX ............... Water Quality Exchange CWSS .............. Community Water System Sur- NRC ................. National Research Council 5:3 acid ........... 2H,2H,3H,3H-Perfluorooctanoic vey NTP ................. National Toxicology Program acid D/DBP ............. Disinfectants/Disinfection By- NWIS ............... National Water Information Sys- 6:2 diPAP ........ Bis[2-(perfluorohexyl)ethyl] products tem phosphate DBP ................. Disinfection Byproduct OA ................... Oxanilic Acid 6:2 monoPAP .. Mono[2-(perfluorohexyl)ethyl] DDE ................. 1,1-Dichloro-2,2-bis(p- OPP ................. Office of Pesticides Program phosphate chlorophenyl)ethylene ORD ................. Office of Research and Develop- 6:2/8:2 diPAP 6:2/8:2 Fluorotelomer phosphate DWI ................. Drinking Water Intake ment diester EPA ................. Environmental Protection Agen- OTC ................. Ornithine Carbamoyl Transferase 8:2 diPAP ........ Bis[2-(perfluorooctyl)ethyl] phos- cy OW .................. Office of Water phate EPCRA ............ Emergency Planning and Com- PCCL ............... Preliminary Contaminant Can- 8:2 monoPAP .. Mono[2-(perfluorooctyl)ethyl] munity Right-To-Know Act didate List phosphate EPTC ............... S-Ethyl dipropylthiocarbamate PDP ................. Pesticide Data Program ESA ................. Ethanesulfonic Acid PFAA .............. Perfluorinated Alkyl Acids FtOH 6:2 ......... 6:2 Fluorotelomer Alcohol PFAS ............... Per- and Polyfluoroalkyl Sub- Table of Contents FtOH 8:2 ......... 8:2 Fluorotelomer Alcohol stances FtS 6:2 ............. 6:2 Fluorotelomer Sulfonic Acid PFBA ............... Perfluorobutanoic Acid I. General Information FtS 8:2 ............. 8:2 Fluorotelomer Sulfonic Acid PFBS ............... Perfluorobutanesulfonic Acid A. Written Comments FQPA .............. Food Quality Protection Act PFDA ............... Perfluorodecanoic Acid B. Does this action apply to me? FR .................... Federal Register PFDS ............... Perfluorodecanesulfonic Acid II. Purpose and Background HA ................... Health Advisory PFHpA ............ Perfluoroheptanoic Acid A. What is the purpose of this action? HDL ................. High-Density Lipoprotein PFHpS ............
Recommended publications
  • US EPA Environmental Technology Verification Statement Removal of Chemical Contaminants in Drinking Water Watts Premier Inc
    THE ENVIRONMENTAL TECHNOLOGY VERIFICATION PROGRAM U.S. Environmental Protection Agency NSF International ETV Joint Verification Statement TECHNOLOGY TYPE: POINT-OF-USE DRINKING WATER TREATMENT SYSTEM APPLICATION: REMOVAL OF CHEMICAL CONTAMINANTS IN DRINKING WATER PRODUCT NAME: WATTS PREMIER WP-4V COMPANY: WATTS PREMIER, INC. ADDRESS: 1725 WEST WILLIAMS DR. SUITE C-20 PHOENIX, AZ 85027 PHONE: 800-752-5582 NSF International (NSF) manages the Drinking Water Systems (DWS) Center under the U.S. Environmental Protection Agency’s (EPA) Environmental Technology Verification (ETV) Program. The DWS Center recently evaluated the performance of the Watts Premier WP-4V point-of-use (POU) drinking water treatment system. NSF performed all of the testing activities, and also authored the verification report and this verification statement. The verification report contains a comprehensive description of the test. EPA created the ETV Program to facilitate the deployment of innovative or improved environmental technologies through performance verification and dissemination of information. The goal of the ETV Program is to further environmental protection by accelerating the acceptance and use of improved and more cost-effective technologies. ETV seeks to achieve this goal by providing high-quality, peer- reviewed data on technology performance to those involved in the design, distribution, permitting, purchase, and use of environmental technologies. ETV works in partnership with recognized standards and testing organizations, stakeholder groups (consisting of buyers, vendor organizations, and permitters), and with the full participation of individual technology developers. The program evaluates the performance of innovative technologies by developing test plans that are responsive to the needs of stakeholders, conducting field or laboratory tests (as appropriate), collecting and analyzing data, and preparing peer reviewed reports.
    [Show full text]
  • Investigating Non-Targeted Screening and Accurate Quantitation of Trace Surface Water Contaminants Using High-Resolution Mass Spectrometry
    Western University Scholarship@Western Electronic Thesis and Dissertation Repository 8-8-2018 3:00 PM Investigating non-targeted screening and accurate quantitation of trace surface water contaminants using high-resolution mass spectrometry Lucas M. Morrison The University of Western Ontario Supervisor Sumarah, Mark W. The University of Western Ontario Co-Supervisor Yeung, Ken K-C. The University of Western Ontario Graduate Program in Chemistry A thesis submitted in partial fulfillment of the equirr ements for the degree in Master of Science © Lucas M. Morrison 2018 Follow this and additional works at: https://ir.lib.uwo.ca/etd Part of the Analytical Chemistry Commons, and the Environmental Chemistry Commons Recommended Citation Morrison, Lucas M., "Investigating non-targeted screening and accurate quantitation of trace surface water contaminants using high-resolution mass spectrometry" (2018). Electronic Thesis and Dissertation Repository. 5612. https://ir.lib.uwo.ca/etd/5612 This Dissertation/Thesis is brought to you for free and open access by Scholarship@Western. It has been accepted for inclusion in Electronic Thesis and Dissertation Repository by an authorized administrator of Scholarship@Western. For more information, please contact [email protected]. Abstract The human impact on surface water is a growing concern and the chemical surveying of contaminants including pharmaceuticals and pesticides is currently lacking. Neonicotinoids in particular, are among the most widely used insecticides that have prompted environmental concern and require monitoring. Chemical contaminants in environmental water samples are commonly analyzed by targeted tandem mass spectrometry. However, this requires a prior knowledge of the contaminants in the area of interest. Here, surface water samples were screened by utilizing optimized data-independent acquisition (DIA) methods and the spectra were databased for future retrospective analysis.
    [Show full text]
  • Transport of Dangerous Goods
    ST/SG/AC.10/1/Rev.16 (Vol.I) Recommendations on the TRANSPORT OF DANGEROUS GOODS Model Regulations Volume I Sixteenth revised edition UNITED NATIONS New York and Geneva, 2009 NOTE The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the Secretariat of the United Nations concerning the legal status of any country, territory, city or area, or of its authorities, or concerning the delimitation of its frontiers or boundaries. ST/SG/AC.10/1/Rev.16 (Vol.I) Copyright © United Nations, 2009 All rights reserved. No part of this publication may, for sales purposes, be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, electrostatic, magnetic tape, mechanical, photocopying or otherwise, without prior permission in writing from the United Nations. UNITED NATIONS Sales No. E.09.VIII.2 ISBN 978-92-1-139136-7 (complete set of two volumes) ISSN 1014-5753 Volumes I and II not to be sold separately FOREWORD The Recommendations on the Transport of Dangerous Goods are addressed to governments and to the international organizations concerned with safety in the transport of dangerous goods. The first version, prepared by the United Nations Economic and Social Council's Committee of Experts on the Transport of Dangerous Goods, was published in 1956 (ST/ECA/43-E/CN.2/170). In response to developments in technology and the changing needs of users, they have been regularly amended and updated at succeeding sessions of the Committee of Experts pursuant to Resolution 645 G (XXIII) of 26 April 1957 of the Economic and Social Council and subsequent resolutions.
    [Show full text]
  • PUBLIC HEALTH STATEMENT Hexachlorobutadiene CAS#: 87-68-3
    PUBLIC HEALTH STATEMENT Hexachlorobutadiene CAS#: 87-68-3 Division of Toxicology May 1994 This Public Health Statement is the summary be exposed to a substance only when you come in chapter from the Toxicological Profile for contact with it. You may be exposed by breathing, Hexachlorobutadiene. It is one in a series of Public eating, or drinking substances containing the Health Statements about hazardous substances and substance or by skin contact with it. their health effects. A shorter version, the ToxFAQsTM is also available. This information is If you are exposed to a substance such as important because this substance may harm you. hexachlorobutadiene, many factors will determine The effects of exposure to any hazardous substance whether harmful health effects will occur and what depend on the dose, the duration, how you are the type and severity of those health effects will be. exposed, personal traits and habits, and whether These factors include the dose (how much), the other chemicals are present. For more information, duration (how long), the route or pathway by which call the ATSDR Information Center at 1-888-422- you are exposed (breathing, eating, drinking, or skin 8737. contact), the other chemicals to which you are _____________________________________ exposed, and your individual characteristics such as age, gender, nutritional status, family traits, life- This Statement was prepared to give you style, and state of health. information about hexachlorobutadiene and to emphasize the human health effects that may result 1.1 WHAT IS HEXACHLOROBUTADIENE? from exposure to it. The Environmental Protection Agency (EPA) has identified 1,350 hazardous waste Hexachlorobutadiene, also known as HCBD, sites as the most serious in the nation.
    [Show full text]
  • Hexachlorobutadiene in Drinking-Water
    WHO/SDE/WSH/03.04/101 English only Hexachlorobutadiene in Drinking-water Background document for development of WHO Guidelines for Drinking-water Quality © World Health Organization 2004 Requests for permission to reproduce or translate WHO publications - whether for sale of for non- commercial distribution - should be addressed to Publications (Fax: +41 22 791 4806; e-mail: [email protected]. The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. The mention of specific companies or of certain manufacturers' products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters. The World Health Organization does not warrant that the information contained in this publication is complete and correct and shall not be liable for any damage incurred as a results of its use. Preface One of the primary goals of WHO and its member states is that “all people, whatever their stage of development and their social and economic conditions, have the right to have access to an adequate supply of safe drinking water.” A major WHO function to achieve such goals is the responsibility “to propose ... regulations, and to make recommendations with respect to international health matters ....” The first WHO document dealing specifically with public drinking-water quality was published in 1958 as International Standards for Drinking-water.
    [Show full text]
  • OECD Environment Health and Safety Publications Series on Testing and Assessment No
    OECD Environment Health and Safety Publications Series on Testing and Assessment No. 21 Detailed Review Paper Appraisal of Test Methods for Sex Hormone Disrupting Chemicals Environment Directorate ORGANISATION FOR ECONOMIC CO-OPERATION AND DEVELOPMENT Paris May 2001 1 Also Published in the Series Testing and Assessment: No. 1, Guidance Document for the Development of OECD Guidelines for Testing of Chemicals (1993; reformatted 1995) No. 2, Detailed Review Paper on Biodegradability Testing (1995) No. 3, Guidance Document for Aquatic Effects Assessment (1995) No. 4, Report of the OECD Workshop on Environmental Hazard/Risk Assessment (1995) No. 5, Report of the SETAC/OECD Workshop on Avian Toxicity Testing (1996) No. 6, Report of the Final Ring-test of the Daphnia magna Reproduction Test (1997) No. 7, Guidance Document on Direct Phototransformation of Chemicals in Water (1997) No. 8, Report of the OECD Workshop on Sharing Information about New Industrial Chemicals Assessment (1997) No. 9 Guidance Document for the Conduct of Studies of Occupational Exposure to Pesticides During Agricultural Application (1997) No. 10, Report of the OECD Workshop on Statistical Analysis of Aquatic Toxicity Data (1998) No. 11, Detailed Review Paper on Aquatic Testing Methods for Pesticides and industrial Chemicals (1998) No. 12, Detailed Review Document on Classification Systems for Germ Cell Mutagenicity in OECD Member Countries (1998) No. 13, Detailed Review Document on Classification Systems for Sensitising Substances in OECD Member Countries 1998) No. 14, Detailed Review Document on Classification Systems for Eye Irritation/Corrosion in OECD Member Countries (1998) No. 15, Detailed Review Document on Classification Systems for Reproductive Toxicity in OECD Member Countries (1998) No.
    [Show full text]
  • Agents for Defense Against Chemical Warfare: Reactivators of Acetylcholinesterase Inhibited with Neurotoxic Organophosphorus Compounds **
    Mil. Med. Sci. Lett. (Voj. Zdrav. Listy) 2015, vol. 84(3), p. 115-127 ISSN 0372-7025 DOI: 10.31482/mmsl.2015.013 REVIEW ARTICLE AGENTS FOR DEFENSE AGAINST CHEMICAL WARFARE: REACTIVATORS OF ACETYLCHOLINESTERASE INHIBITED WITH NEUROTOXIC ORGANOPHOSPHORUS COMPOUNDS ** Petronilho, E. C., Figueroa-Villar, J. D. Chemistry Engineering Section, Medicinal Chemistry Group, Military Institute of Engineering, Praça General Tibúrcio, 80, Urca, 22290-270, Rio de Janeiro, RJ, Brazil. Received 30 th April 2015. Revised 7 th July 2015. Published 4 th September 2015. Summary The chemical warfare agents and neurotoxic agents are an important threat to people all over the world, and require special attention because they are highly dangerous. Most of these agents are neurotoxic organophosphorus compounds (OP), which inhibit the enzyme acetylcholinesterase (AChE), which is responsible for controlling the transmission of nerve impulses. To be inhibited by these compounds, AChE can sometimes be reactivated using cationic oximes, which are the most used substances for this reactivation. Until today there have not been discovered agents for complete treatment of poisoning by all OPs. For this reason, the treatment of intoxicated people requires the determination of the absorbed OP, in order to select the appropriate activator, a process that usually requires long time and may cause death. Therefore, this study aims to do a review on the OPs used as chemical warfare agents and the process of inhibition and reactivation of AChE, especially to motivate the development of new agents for defense against chemical weapons, a process that is very important for protecting all humanity. Key words: acetylcholinesterase; AChE reactivators; organophosphorus; oximes; warfare agents INTRODUCTION pounds (OP), which are highly toxic, allowing their use with small quantities in order to cause seizures The use of chemical warfare agents is a major and death.
    [Show full text]
  • EPA Method 538: Determination of Selected Organic Contaminants in Drinking Water with Direct Aqueous Injection LC/MS/MS
    EPA Method 538: Determination of Selected Organic Contaminants in Drinking Water with Direct Aqueous Injection LC/MS/MS E. Michael Thurman and Imma Ferrer Center for Environmental Mass Spectrometry University of Colorado Boulder, CO, USA Confidentiality Label 1 March 20, 2012 Abstract EPA Method 538 is a new method from EPA for organophosphate pesticides in drinking water. It uses direct aqueous injection; thus, no sample preparation is needed. We use both UHPLC (Agilent 1290) and MS/MS (Agilent 6460) analysis for rapid analysis and sensitive detection with ng/L limits of detection. A second MRM is added for more reliable identification. Confidentiality Label 2 March 20, 2012 Hypothesis Direct injection of organophosphate pesticides (EPA Method 538) will work by UHPLC (Agilent Model 1290) and LC/MS/MS with Jetstream (Agilent Model 6460) with trace level detection at ng/L concentrations. Confidentiality Label 3 March 20, 2012 1. Introduction-Summary 1.1 EPA Method 538 (published in November 2009 by Shoemaker) deals with Organophosphate pesticides in drinking water (1) and one other contaminant, quinoline. 1.2 The method consists of 10 compounds: acephate, aldicarb, aldicarb sulfoxide, dicrotophos, diisopropylmethylphosphonate (DIMP), fenamiphos sulfone, fenamiphos sulfoxide, methamidophos, oxydemeton methyl, quinoline, and thiofanox with 5 labeled internal standards. 1.3 Direct aqueous injection is used with a large volume sample of 100 microliters; thus, no sample preparation is needed. 1.4 Because solid phase extraction (i.e. concentration of the sample is not carried out) suppression is mimimized in the analysis. 1.5 Part-per-Trillion Detection Limits. Confidentiality Label 4 March 20, 2012 Introduction 1.1: EPA Method 538: Determination of Selected Organic Contaminants in Drinking Water by Direct Aqueous Injection by Jody Shoemaker, EPA Cincinnati, OH [email protected] 513-569-7298 Confidentiality Label 5 March 20, 2012 Introduction: 1.2.
    [Show full text]
  • EPA Method 538: Determination of Selected Organic Contaminants in Drinking Water by Aqueous Direct Injection and LC/MS/MS Summar
    EPA Method 538: Determination of Selected Organic Contaminants in Drinking Water by Aqueous Direct Injection and LC/MS/MS UCT Part Numbers: SLAQ100ID21-3UM - Selectra® Aqueous C18, 100 x 2.1mm, 3µm SLAQGDC20-3UM - Selectra® Aqueous C18, Guard column, 10 x 2.0mm, 3µm SLGRDHLDR - Guard Cartridge Holder June 2015 Summary: This application outlines a direct aqueous injection-liquid chromatography/tandem mass spectrometry (DAI-LC/MS/MS) method for the determination of 11 selected organic contaminants in drinking water, including methamidophos, acephate, aldicarb sulfoxide, oxydemeton methyl, dicrotophos, aldicarb, diisopropyl methylphosphonate (DIMP), fenamiphos sulfone, fenamiphos sulfoxide, thiofanox, and quinoline [1]. Dicrotophos, oxydemeton methyl, methamidophos, and acephate are UCMR4 compounds. An Aqueous C18 HPLC column was utilized for analyte retention and separation. Calibration curves were constructed using calibration standards prepared in reagent water with preservative reagents for analyte quantitation. The responses were linear over the entire analytical ranges (R2 ≥ 0.9970). Excellent accuracy (90 - 111%) and precision (RSD% < 20%, n=7) were achieved for fortified reagent water and tap water samples. Procedure: 1. Preserve drinking water sample with 64 mg/L of sodium omadine (antimicrobial) and 1.5 g/L of ammonium acetate (binding free chlorine). 2. Mix 0.99 mL of the preserved water sample with 10 μL of 0.4-12.5 ng/μL internal standard mixture, and vortex for 30 sec. 3. Inject 50 μL onto LC/MS/MS equipped with an aqueous
    [Show full text]
  • UNITED NATIONS Stockholm Convention on Persistent Organic
    UNITED NATIONS SC UNEP/POPS/POPRC.12/INF/12 Distr.: General 25 July 2016 English only Stockholm Convention on Persistent Organic Pollutants Persistent Organic Pollutants Review Committee Twelfth meeting Rome, 1923 September 2016 Item 4 (c) (ii) of the provisional agenda* Technical work: consideration of recommendations to the Conference of the Parties: unintentional releases of hexachlorobutadiene Draft evaluation of new information in relation to listing of hexachlorobutadiene in Annex C to the Stockholm Convention Note by the Secretariat As referred to in the note by the Secretariat on new information in relation to the listing of hexachlorobutadiene in Annex C to the Stockholm Convention (UNEP/POPS/POPRC.12/6), the annex to the present note sets out the draft evaluation of new information in relation to listing of hexachlorobutadiene in Annex C to the Stockholm Convention. The present note, including its annex, has not been formally edited. * UNEP/POPS/POPRC.12/1. 250716 UNEP/POPS/POPRC.12/INF/12 Annex Draft evaluation of new information in relation to the listing of hexachlorobutadiene in Annex C of the Stockholm Convention June 2016 2 UNEP/POPS/POPRC.12/INF/12 Table of Contents Executive summary .................................................................................................................................... 4 1. Introduction ..................................................................................................................................... 6 1.1 Overview ............................................................................................................................
    [Show full text]
  • Nitrobenzene
    This report contains the collective views of an international group of experts and does not necessarily represent the decisions or the stated policy of the United Nations Environment Programme, the International Labour Organization or the World Health Organization. Environmental Health Criteria 230 NITROBENZENE First draft prepared by L. Davies, Office of Chemical Safety, Therapeutic Goods Administration, Australian Department of Health and Ageing, Canberra, Australia Plese note that the pagination and layout of this web verson are not identical to those of the (to be) printed document Published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organization and the World Health Organization, and produced within the framework of the Inter-Organization Programme for the Sound Management of Chemicals. World Health Organization Geneva, 2003 The International Programme on Chemical Safety (IPCS), established in 1980, is a joint venture of the United Nations Environment Programme (UNEP), the International Labour Organization (ILO) and the World Health Organization (WHO). The overall objectives of the IPCS are to establish the scientific basis for assessment of the risk to human health and the environment from exposure to chemicals, through international peer review processes, as a prerequisite for the promotion of chemical safety, and to provide technical assistance in strengthening national capacities for the sound management of chemicals. The Inter-Organization Programme for the Sound Management of Chemicals (IOMC) was established in 1995 by UNEP, ILO, the Food and Agriculture Organization of the United Nations, WHO, the United Nations Industrial Development Organization, the United Nations Institute for Training and Research and the Organisation for Economic Co-operation and Development (Participating Organizations), following recommendations made by the 1992 UN Conference on Environment and Development to strengthen cooperation and increase coordination in the field of chemical safety.
    [Show full text]
  • Toxicological Profile for Glyphosate Were
    A f Toxicological Profile for Glyphosate August 2020 GLYPHOSATE II DISCLAIMER Use of trade names is for identification only and does not imply endorsement by the Agency for Toxic Substances and Disease Registry, the Public Health Service, or the U.S. Department of Health and Human Services. GLYPHOSATE III FOREWORD This toxicological profile is prepared in accordance with guidelines developed by the Agency for Toxic Substances and Disease Registry (ATSDR) and the Environmental Protection Agency (EPA). The original guidelines were published in the Federal Register on April 17, 1987. Each profile will be revised and republished as necessary. The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects information for these toxic substances described therein. Each peer-reviewed profile identifies and reviews the key literature that describes a substance's toxicologic properties. Other pertinent literature is also presented, but is described in less detail than the key studies. The profile is not intended to be an exhaustive document; however, more comprehensive sources of specialty information are referenced. The focus of the profiles is on health and toxicologic information; therefore, each toxicological profile begins with a relevance to public health discussion which would allow a public health professional to make a real-time determination of whether the presence of a particular substance in the environment poses a potential threat to human health. The adequacy of information to determine a substance's
    [Show full text]