ENGINEERED FOR EFFICIENCY KemZYME® Protease Precision Delivery with Accuracy EFFICIENCY IN ANIMAL PROTEIN PRODUCTION

Ef cienct animal protein production is the driving factor for sustaining pro tability. Feed nutrient utilization remains single most inevitable factor on ef ciency in animal protein production.

Scope for Nutrient Utilization Protein Nutrition at Improvement in Broilers Different Stages of Broilers

YOUNG ADULT

Feed Protein Intake

Protein Requirement 1.0 Million Birds

Endogenous Protease

Protein Utilization

Protease Requirement

1400 Mt Meat 300 MT Meat Nutrient Ultilization Equivalent to un-utilized nutrients PROTEIN EFFICIENCY RATIO (PER) IN BROILERS (Body weight gain in grams for each gram protein intake)

PER (g:g) PER (g:g) 3.0 2.50 PER (g:g) 2.75 PER (g:g) 3.50

Pre-Starter Starter Finisher Lifetime

Protein utilization in converting the feed protein to meat protein is approximately 40% in broilers. Improving the protein digestibility will help to enhance the PER and Protein Utilization. SCOPE FROM FEED MATERIALS NEED FOR A PARADIGM SHIFT

100% KemZYME® Protease 95% Criteria Other Protease

90% Type of Protease Single Protease Multi Protease 85% Thermo-stability Yes Yes 80%

75% Gastric-stability Low High Protein Digestibility (%) 70% Sustained Release Low High 65% RM Compatibility Medium FM High GOC PKM CSM RSM SBM MBM DORB MGM DDGS Maize Wheat SFDOC G.Meal FF Soya DOGNC Blood M. Copra M. R. Gluten Chicken M. Nutritional Matrix Yes Yes Utilized AA Unutilized AA Performance Medium High Percentile of Utilized & Un-utilized feed Nitrogen MULTI-PROTEASE DELIVERS DIFFERENTLY

KemZYME® Protease is the unique multi-protease system with a patented target release technology for gastric acid stability; with high activity and thermo-stability delete. This ensures a superior amino acid release throughout GI tract as well broad-spectrum ingredient compatibility.

Through Acid Protease » Pepsin Type Protease GI tract Thermal Stability » Broad Spectrum Substrate Speci city

Thermo KemZYME® RM Neutral Protease » Strong Metallo Endo-Peptidase Compatibility Thermal & Gastric » Cleaves Peptides at Multiple Sites stability Protease Stability

Gastric Alkaline Protease » Broad Spectrum Serine Endopeptidase Thermal & Gastric » Strong Peptide Cleaving Capacity Activity Stability

Uniqueness of KemZYME® Protease

KemZYME® Protease BROAD-SPECTRUM INGREDIENT THE MULTI - PROTEASE ADVANTAGE COMPATIBILITY:

The multi-protease in KemZYME® Protease ensures a better amino acids release from various feed ingredients over Delivers single alkaline proteases. Superior Economics Replaces 112 Digestible Broad-spectrum Ingredient 110 Amino Acids Compability 108

KemZYME® 106 Avg+5.7% Protease Multi protease 104 Enhancing Avg+2.6% Single protease Overall Delivers on 102 Corn-soy Perfomance Diets 100

Improves Relative Digestibility (%) 98 Carcass yield 96 94 Corn Gluten Soybean DDGS Feather Fish Meal Meat BoneRape seed Rice Bran Meal Meal Meal Meal Meal Meal

Control NSP + Single protease NSP + Multiprotease Differential bene ts of KemZYME® Protease Source: WP-07-00051 in Broiler ration

85 Relative DELIVERS ON CORN-SOYBEAN DIETS Improvement 84.17 84 83.74 + 0.52%

83 Relative Use of multi-protease in corn soy diets allows better Improvement 82.15 + 2.46% bio-availability of amino acids over single proteases. This 82 allows replacing crude protein and amino acids to reduce Digestibility (%) production cost. 81 80 Control Single-Protease Multi-Protease Average Amino Acid Digestibility Improvement (Corn-Soy Diets) Source: WP-07-00051 IMPROVES FLOCK PERFORMANCE & CARCASS YIELD

Incorporation of KemZYME® Protease for broiler diets allows reducing the crude protein from the diet, thus controlling the production cost. Both reformulation and on-top application improved the broiler performance and carcass yield with reduced production cost. 75.0 74.5 74.0 Livability Carcass ADG(g) ADFI(g) FCR 73.5 74.32

(%) Yield (%) 74.04 73.0 Positive Control 73.39 (Normal Diet) 51.7 92.3 91.07 1.79 72.26 72.5 72.0 Positive Control + Carcass Yield (%) KemZYME® Protease 52.2 92.2 91.97 1.77 74.32 71.5 72.26 71.0 Negative Control (Reformulated) 52.8 97.1 93.75 1.84 73.39 70.5 70.0 Negative Control + KemZYME® Protease 53.8 96.2 91.97 1.79 74.04 Carcass Yield (%) PC PC+Kz P NC NC+Kz P

Source : PDP, Hyderabad (Data under publication) Source: PDP, Hyderabad (Data under Publication)

REPLACES DIGESTIBLE AMINO ACIDS DELIVERS SUPERIOR ECONOMICS

KemZYME® Protease allows reducing the digestible amino On a comparative study with similar concepts on pellet acid levels in the formulation with improved performance diets with reduced protein, KemZYME® Protease helped to and ock economics. minimize the production cost.

2.5 53.33 53.5 2.60 2.0 53.0 2.35 2.34 2.40 2.25 52.5 1.5 52.30 1.80 52.05 1.61 1.58 1.58 51.77 52.0 1.60 1.0 51.5 1.40 0.5 51.0 Production Cost / Kg (INR)

1.00 (Perfomance Parameters) 2.35 1.58 2.4 1.56 2.33 1.57 2.38 1.56 BW (Kg) CFCR 0.0 50.5 Positive KemZYME® Protease Brand A Brand B Positive Control Negative Control (-0.9% CP & 5% Dig AA) Control Negative Control + KemZYME® Protease BW (kg) CFCR Production Cost/kg Live Weight

Source: TILMAH (Data under publication) Source: TILMAH (Data under publication) APPLICATION

KemZYME® Protease recommended through reformulation with diet speci c matrix values as well on top application.

Reformulation : 300 g/mt with 3-5 % digestible Amino acids On-top Application : 150 gms per tonne of feed. Note : Please contact Kemin technical team for ideal application and matrix values