Circulation Journal Supplementary File Official Journal of the Japanese Circulation Society http://www.j-circ.or.jp Circ J 2016; 80: 2327 – 2335 The Current Status of Cardiovascular Medicine in Japan – Analysis of a Large Number of Health Records From a Nationwide Claim-Based Database, JROAD-DPC – Satoshi Yasuda, MD, PhD; Kazuhiro Nakao, MD; Kunihiro Nishimura, MD, PhD; Yoshihiro Miyamoto, MD, PhD; Yoko Sumita; Toshiaki Shishido, MD, PhD; Toshihisa Anzai, MD, PhD; Hiroyuki Tsutsui, MD, PhD; Hiroshi Ito, MD, PhD; Issei Komuro, MD, PhD; Yoshihiko Saito, MD, PhD; Hisao Ogawa, MD, PhD on the behalf of JROAD Investigators

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Table S1. Diagnosis Codes for Data Extraction in JROAD- I220 Subsequent STEMI of anterior wall DPC I221 Subsequent STEMI of inferior wall ICD10 code Diagnosis I228 Subsequent STEMI of other site I050 Rheumatic mitral I229 Subsequent STEMI of unspecified site I051 Rheumatic mitral insufficiency I230 as current complication follow- ing AMI I052 Rheumatic mitral stenosis with insufficiency I231 as current complication follow- I058 Other rheumatic diseases ing AMI I059 Rheumatic mitral valve disease, unspecified I232 Ventricular septal defect as current complication I060 Rheumatic following AMI I061 Rheumatic I233 Rupture of cardiac wall without hemopericardium I062 Rheumatic aortic stenosis with insufficiency as current complication following AMI I068 Other rheumatic diseases I234 Rupture of chordae tendineae as current compli- cation following AMI I069 Rheumatic aortic valve disease, unspecified I235 Rupture of papillary muscle as current complica- I070 Rheumatic tricuspid stenosis tion following AMI I071 Rheumatic tricuspid insufficiency I236 Thrombosis of atrium, auricular appendage, and I072 Rheumatic tricuspid stenosis and insufficiency ventricle as current complications following AMI I078 Other rheumatic diseases I238 Other current complications following AMI I079 Rheumatic tricuspid valve disease, unspecified I240 Acute not resulting in I080 Rheumatic disorders of both mitral and aortic valves I241 Dressler’s syndrome I081 Rheumatic disorders of both mitral and tricuspid I248 Other forms of acute ischemic disease valves I249 Acute ischemic heart disease, unspecified I082 Rheumatic disorders of both aortic and tricuspid I250 Atherosclerotic heart disease of native coronary valves artery I083 Combined rheumatic disorders of mitral, aortic I251 Atherosclerotic heart disease of native coronary and tricuspid valves artery I088 Other rheumatic multiple valve diseases I252 Old myocardial infarction I089 Rheumatic multiple valve disease, unspecified I253 Aneurysm of heart I090 Rheumatic I254 Coronary artery aneurysm and dissection I091 Rheumatic diseases of , valve I255 Ischemic unspecified I256 Silent myocardial I092 Chronic rheumatic I258 Other forms of chronic ischemic heart disease I200 Unstable I259 Chronic ischemic heart disease, unspecified I201 Angina pectoris with documented spasm I340 Nonrheumatic mitral (valve) insufficiency I208 Other forms of angina pectoris I341 Nonrheumatic mitral (valve) prolapse I209 Angina pectoris, unspecified I342 Nonrheumatic mitral (valve) stenosis I210 STEMI of anterior wall I348 Other nonrheumatic mitral valve disorders I211 STEMI of inferior wall I349 Nonrheumatic mitral valve disorder, unspecified I212 STEMI of other sites I350 Nonrheumatic aortic (valve) stenosis I213 STEMI of unspecified site I351 Nonrheumatic aortic (valve) insufficiency I214 NSTEMI I219 STEMI, unspecified (Table S1 continued the next page.)

Circulation Journal Vol.80, November 2016 I352 Nonrheumatic aortic (valve) stenosis with insuffi- I512 Rupture of papillary muscle, not elsewhere classi- ciency fied I358 Other nonrheumatic aortic valve disorders I513 Intracardiac thrombosis, not elsewhere classified I359 Nonrheumatic aortic valve disorder, unspecified I514 Myocarditis, unspecified I360 Nonrheumatic tricuspid (valve) stenosis I515 Myocardial degeneration I361 Nonrheumatic tricuspid (valve) insufficiency I516 CVD, unspecified I362 Nonrheumatic tricuspid (valve) stenosis with I517 insufficiency I518 Other ill-defined heart diseases I368 Other nonrheumatic tricuspid valve disorders I519 Heart disease, unspecified I369 Nonrheumatic tricuspid valve disorder, unspecified I520 Other heart disorders in bacterial diseases classi- I370 Nonrheumatic stenosis fied elsewhere I371 Nonrheumatic pulmonary valve insufficiency I521 Other heart disorders in other infectious and I372 Nonrheumatic pulmonary valve stenosis with parasitic diseases classified elsewhere insufficiency I528 Other heart disorders in other diseases classified I378 Other nonrheumatic pulmonary valve disorders elsewhere I379 Nonrheumatic pulmonary valve disorder, unspeci- I710 Dissection of aorta [any part] fied I711 Thoracic aortic aneurysm, ruptured I38 , valve unspecified I712 Thoracic aortic aneurysm, without mention of I390 Mitral valve disorders in diseases classified else- rupture where I713 Abdominal aortic aneurysm, ruptured I391 Aortic valve disorders in diseases classified else- I714 Abdominal aortic aneurysm, without mention of where rupture I392 Tricuspid valve disorders in diseases classified I715 Thoracoabdominal aortic aneurysm, ruptured elsewhere I716 Thoracoabdominal aortic aneurysm, without I393 Pulmonary valve disorders in diseases classified mention of rupture elsewhere I718 Aortic aneurysm of unspecified site, ruptured I394 Multiple valve disorders in diseases classified I719 Aortic aneurysm of unspecified site, without elsewhere mention of rupture I398 Endocarditis, valve unspecified, in diseases clas- I720 Aneurysm and dissection of carotid artery sified elsewhere I722 Aneurysm and dissection of renal artery I420 I723 Aneurysm and dissection of iliac artery I421 Obstructive hypertrophic cardiomyopathy I724 Aneurysm and dissection of artery of lower I422 Other hypertrophic cardiomyopathy extremity I423 Endomyocardial (eosinophilic) disease I728 Aneurysm and dissection of other specified arter- I424 Endocardial fibroelastosis ies I425 Other restrictive cardiomyopathy I730 Raynaud syndrome I426 I731 Thromboangiitis obliterans [Buerger] I427 Cardiomyopathy due to drugs and other external I800 Phlebitis and thrombophlebitis of superficial agents vessels of lower extremities I431 Cardiomyopathy in metabolic diseases I801 Phlebitis and thrombophlebitis of femoral vein I438 Cardiomyopathy in other diseases classified else- I802 Phlebitis and thrombophlebitis of other deep where vessels of lower extremities I441 , second degree I803 Phlebitis and thrombophlebitis of lower extremi- I442 Atrioventricular block, complete ties, unspecified I443 Other and unspecified atrioventricular block