Review Contributions to the Field of Neurotransmitters by Japanese Scientists, and Reflections on My Own Research
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Layered Reward Signalling Through Octopamine and Dopamine in Drosophila: a Dissertation
University of Massachusetts Medical School eScholarship@UMMS GSBS Dissertations and Theses Graduate School of Biomedical Sciences 2013-05-10 Layered Reward Signalling Through Octopamine and Dopamine in Drosophila: A Dissertation Christopher J. Burke University of Massachusetts Medical School Let us know how access to this document benefits ou.y Follow this and additional works at: https://escholarship.umassmed.edu/gsbs_diss Part of the Neuroscience and Neurobiology Commons Repository Citation Burke CJ. (2013). Layered Reward Signalling Through Octopamine and Dopamine in Drosophila: A Dissertation. GSBS Dissertations and Theses. https://doi.org/10.13028/M2S309. Retrieved from https://escholarship.umassmed.edu/gsbs_diss/657 This material is brought to you by eScholarship@UMMS. It has been accepted for inclusion in GSBS Dissertations and Theses by an authorized administrator of eScholarship@UMMS. For more information, please contact [email protected]. LAYERED REWARD SIGNALLING THROUGH OCTOPAMINE AND DOPAMINE IN DROSOPHILA A Dissertation Presented By Christopher J. Burke Submitted to the Faculty of the University of Massachusetts Graduate School of Biomedical Sciences, Worcester in partial fulfillment of the requirements for the degree of DOCTOR OF PHILOSOPHY Friday, The Tenth of May, 2013 Program in Neuroscience LAYERED REWARD SIGNALLING THROUGH OCTOPAMINE AND DOPAMINE IN DROSOPHILA A Dissertation Presented By Christopher J. Burke The signatures of the Dissertation Defense Committee signifies completion and approval as to style and -
Curriculum Vitae 1/2021
CURRICULUM VITAE 1/2021 John G. Hildebrand Department of Neuroscience Telephone: (520) 621-6626 College of Science, School of Mind, Brain & Behavior Fax: (520) 621-8282 University of Arizona Email: [email protected] PO Box 210077 Website: https://neurosci.arizona.edu/person/john-hildebrand-phd Tucson AZ 85721-0077 Spouse: Gail D. Burd, Ph.D. Education 1964 A.B. Harvard University (Biology – mentors: John Law & Konrad Bloch) 1966 Harvard Medical School, summer training program in general pathology 1969 Ph.D. Rockefeller University (Bio-organic chemistry – mentors: Leonard Spector & Fritz Lipmann) 1969-71 Postdoctoral Fellow, Harvard Medical School, Department of Neurobiology (mentor: Edward Kravitz) 1977 Cold Spring Harbor Laboratory course, Methods in Cellular Neurophysiology 1993 DNA Methods Course, University of Arizona Division of Biotechnology Employment Present Positions 2014-now Foreign Secretary, U.S. National Academy of Sciences 2010-now Honors Professor, University of Arizona 1989-now Regents Professor, University of Arizona 1985-now Professor of Neuroscience, Chemistry & Biochemistry, Ecology & Evolutionary Biology, Entomology, and Molecular & Cellular Biology, University of Arizona Previous Positions 2009-13 founding Head, Dept. of Neuroscience (formerly ARL Div. Neurobiology), Univ. of Arizona 2010-12 Chairman, Executive Committee, UA School of Mind, Brain and Behavior 1986-97 Chairman, UA Committee on Neuroscience, University of Arizona 1985-2009 founding Director, Arizona Research Laboratories Division of Neurobiology, -
The Effects of Serotonin and 5-Carboxamidotryptamine on Aggressive Behavior in Crayfish Pair Interactions
THE EFFECTS OF SEROTONIN AND 5-CARBOXAMIDOTRYPTAMINE ON AGGRESSIVE BEHAVIOR IN CRAYFISH PAIR INTERACTIONS LISA MANGIAMELE Introduction Agonistic interactions between decapod crustaceans consist of a series of bouts characterized by combative use of the claws to strike, grasp, and restrain the opponent. The antennae may also be used as weapons to tap or whip the body of another individual. Fights that escalate in intensity often involve one animal pulling or lifting its opponent above the substrate, and those battles that reach the highest level of intensity may result in individuals attempting to violently break off the appendages of the opponent. These aggressive behaviors are highly stereotyped, and usually interactions result in a clear winner and loser (Bruski and Dunham 1987; Huber and Kravitz 1995). Changes in behavior during these interactions, where winning appears to reinforce aggressive behavior while losing appears to inhibit aggression, aid in the formation of a dominance hierarchy (Issa et al 1999). The neurohormone serotonin [5-hydroxytryptamine (5HT)] has been linked to agonistic behavior and aggressive posturing in lobsters and crayfish (Livingstone et al. 1980; Antonsen and Paul 1997; Huber et al. 1997). Crayfish treated with 5HT show increased intensity of aggressive response to conspecifics, and are more likely to continue fighting in situations that would normally evoke a retreat (Huber et al. 1997). The similarity of this response to the increased aggression exhibited by dominant animals suggests a role for endogenous serotonin in fighting behavior and the maintenance of social status. In addition, amine injection has been found to elicit characteristic postures in the absence of external stimuli. -
Alumni Director Cover Page.Pub
Harvard University Program in Neuroscience History of Enrollment in The Program in Neuroscience July 2018 Updated each July Nicholas Spitzer, M.D./Ph.D. B.A., Harvard College Entered 1966 * Defended May 14, 1969 Advisor: David Poer A Physiological and Histological Invesgaon of the Intercellular Transfer of Small Molecules _____________ Professor of Neurobiology University of California at San Diego Eric Frank, Ph.D. B.A., Reed College Entered 1967 * Defended January 17, 1972 Advisor: Edwin J. Furshpan The Control of Facilitaon at the Neuromuscular Juncon of the Lobster _______________ Professor Emeritus of Physiology Tus University School of Medicine Albert Hudspeth, M.D./Ph.D. B.A., Harvard College Entered 1967 * Defended April 30, 1973 Advisor: David Poer Intercellular Juncons in Epithelia _______________ Professor of Neuroscience The Rockefeller University David Van Essen, Ph.D. B.S., California Instute of Technology Entered 1967 * Defended October 22, 1971 Advisor: John Nicholls Effects of an Electronic Pump on Signaling by Leech Sensory Neurons ______________ Professor of Anatomy and Neurobiology Washington University David Van Essen, Eric Frank, and Albert Hudspeth At the 50th Anniversary celebraon for the creaon of the Harvard Department of Neurobiology October 7, 2016 Richard Mains, Ph.D. Sc.B., M.S., Brown University Entered 1968 * Defended April 24, 1973 Advisor: David Poer Tissue Culture of Dissociated Primary Rat Sympathec Neurons: Studies of Growth, Neurotransmier Metabolism, and Maturaon _______________ Professor of Neuroscience University of Conneccut Health Center Peter MacLeish, Ph.D. B.E.Sc., University of Western Ontario Entered 1969 * Defended December 29, 1976 Advisor: David Poer Synapse Formaon in Cultures of Dissociated Rat Sympathec Neurons Grown on Dissociated Rat Heart Cells _______________ Professor and Director of the Neuroscience Instute Morehouse School of Medicine Peter Sargent, Ph.D. -
Curriculum Vitae RONALD MORGAN HARRIS-WARRICK Professor Section of Neurobiology and Behavior Cornell University Biographical
Curriculum Vitae RONALD MORGAN HARRIS-WARRICK Professor Section of Neurobiology and Behavior Cornell University Biographical Data: Birthplace - Berkeley, California Birthdate - July 28, 1949 Citizenship - U.S.A. Marital status - Married, two children Education: B.A. Biological Sciences, Stanford University, 1970 Ph.D. Genetics, Stanford University School of Medicine, 1976 Thesis advisor: Dr. Joshua Lederberg; Title: "DNA segmentation and sequence heterology in transformation of Bacillus subtilis" Work Experience: 1970-73 Research Assistant, Department of Genetics, Stanford University School of Medicine; Advisor: Dr. Joshua Lederberg 1976-78 NIH Postdoctoral Fellow, Department of Neurobiology, Stanford University, School of Medicine; Advisor: Dr. Eric M. Shooter 1978-80 Muscular Dystrophy Association Postdoctoral Fellow, Department of Neurobiology, Harvard Medical School, Boston, Massachusetts; Advisor: Dr. Edward A. Kravitz 1980-86 Assistant Professor, Section of Neurobiology and Behavior, Cornell University, Ithaca, New York 1986-1992 Associate Professor, Section of Neurobiology and Behavior, Cornell University, Ithaca, New York 1986-87 Visiting Scientist, Laboratoire de Neurobiologie, Ecole Normale Superieure, Paris, France 1988-1991 Associate Chairman, Section of Neurobiology and Behavior, Cornell University, Ithaca, New York 1992-present Professor, Section of Neurobiology and Behavior, Cornell University, Ithaca, New York 1994 Visiting Professor, Department of Molecular and Cellular Physiology, Stanford University School of Medicine -
John G. Hildebrand
CURRICULUM VITAE 9/2019 John G. Hildebrand Department of Neuroscience Telephone: (520) 621-6626 College of Science, School of Mind, Brain & Behavior Fax: (520) 621-8282 University of Arizona Email: [email protected] PO Box 210077 Website: http://neurosci.arizona.edu/john-g-hildebrand Tucson AZ 85721-0077 Spouse: Gail D. Burd, Ph.D. Education 1964 A.B. Harvard University (Biology – mentors: John Law & Konrad Bloch) 1966 Harvard Medical School, summer training program in general pathology 1969 Ph.D. Rockefeller University (Bio-organic chemistry – mentors: Leonard Spector & Fritz Lipmann) 1969-71 Postdoctoral Fellow, Harvard Medical School, Department of Neurobiology (mentor: Edward Kravitz) 1977 Cold Spring Harbor Laboratory course, Methods in Cellular Neurophysiology 1993 DNA Methods Course, University of Arizona Division of Biotechnology Employment Present Positions 2014-now Foreign Secretary, U.S. National Academy of Sciences 2010-now Honors Professor, University of Arizona 1989-now Regents Professor, University of Arizona 1985-now Professor of Neuroscience, Chemistry & Biochemistry, Ecology & Evolutionary Biology, Entomology, and Molecular & Cellular Biology, University of Arizona Previous Positions 2009-13 founding Head, Dept. of Neuroscience (formerly ARL Div. Neurobiology), Univ. of Arizona 2010-12 Chairman, Executive Committee, UA School of Mind, Brain and Behavior 1986-97 Chairman, UA Committee on Neuroscience, University of Arizona 1985-2009 founding Director, Arizona Research Laboratories Division of Neurobiology, Univ. -
The Neuro Nobels
NEURO NOBELS Richard J. Barohn, MD Gertrude and Dewey Ziegler Professor of Neurology University Distinguished Professor Vice Chancellor for Research President Research Institute Research & Discovery Director, Frontiers: The University of Kansas Clinical and Translational Science Grand Rounds Institute February 14, 2018 1 Alfred Nobel 1833-1896 • Born Stockholm, Sweden • Father involved in machine tools and explosives • Family moved to St. Petersburg when Alfred was young • Father worked on armaments for Russians in the Crimean War… successful business/ naval mines (Also steam engines and eventually oil).. made and lost fortunes • Alfred and brothers educated by private teachers; never attended university or got a degree • Sent to Sweden, Germany, France and USA to study chemical engineering • In Paris met the inventor of nitroglycerin Ascanio Sobrero • 1863- Moved back to Stockholm and worked on nitro but too dangerous.. brother killed in an explosion • To make it safer to use he experimented with different additives and mixed nitro with kieselguhr, turning liquid into paste which could be shaped into rods that could be inserted into drilling holes • 1867- Patented this under name of DYNAMITE • Also invented the blasting cap detonator • These inventions and advances in drilling changed construction • 1875-Invented gelignite, more stable than dynamite and in 1887, ballistics, predecessor of cordite • Overall had over 350 patents 2 Alfred Nobel 1833-1896 The Merchant of Death • Traveled much of his business life, companies throughout Europe and America • Called " Europe's Richest Vagabond" • Solitary man / depressive / never married but had several love relationships • No children • This prompted him to rethink how he would be • Wrote poetry in English, was considered remembered scandalous/blasphemous. -
John G. Hildebrand
CURRICULUM VITAE 8/2014 John G. Hildebrand Department of Neuroscience Telephone: (520) 621-6626 College of Science, School of Mind, Brain & Behavior Fax: (520) 621-8282 University of Arizona Email: [email protected] PO Box 210077 Website: http://neurosci.arizona.edu/user/86 Tucson AZ 85721-0077 Spouse: Gail D. Burd, Ph.D. Education 1964 A.B. Harvard University (Biology – mentors: John Law & Konrad Bloch) 1966 Harvard Medical School, summer training program in general pathology 1969 Ph.D. Rockefeller University (Biochemistry – mentors: Leonard Spector & Fritz Lipmann) 1969-71 Postdoctoral Fellow, Harvard Medical School, Department of Neurobiology (mentor: Edward Kravitz) 1977 Cold Spring Harbor Laboratory course, Methods in Cellular Neurophysiology 1993 DNA Methods Course, University of Arizona Division of Biotechnology Employment Present Positions 2014-18 Foreign Secretary, U.S. National Academy of Sciences 2010-now Honors Professor, University of Arizona 1989-now Regents Professor, University of Arizona 1985-now Professor of Neuroscience, Chemistry & Biochemistry, Ecology & Evolutionary Biology, Entomology, and Molecular & Cellular Biology, University of Arizona Previous Positions 2009-13 founding Head, Dept. of Neuroscience (formerly ARL Div. Neurobiology), Univ. of Arizona 2010-12 Chairman, Executive Committee, UA School of Mind, Brain and Behavior 1986-97 Chairman, UA Committee on Neuroscience, University of Arizona 1985-2009 founding Director, Arizona Research Laboratories Division of Neurobiology, Univ. of Arizona 1981-86 -
Developing a 21St Century Neuroscience Workforce: Workshop Summary
This PDF is available from The National Academies Press at http://www.nap.edu/catalog.php?record_id=21697 Developing a 21st Century Neuroscience Workforce: Workshop Summary ISBN Sheena M. Posey Norris, Christopher Palmer, Clare Stroud, and Bruce M. 978-0-309-36874-2 Altevogt, Rapporteurs; Forum on Neuroscience and Nervous System Disorders; Board on Health Sciences Policy; Institute of Medicine 130 pages 6 x 9 PAPERBACK (2015) Visit the National Academies Press online and register for... Instant access to free PDF downloads of titles from the NATIONAL ACADEMY OF SCIENCES NATIONAL ACADEMY OF ENGINEERING INSTITUTE OF MEDICINE NATIONAL RESEARCH COUNCIL 10% off print titles Custom notification of new releases in your field of interest Special offers and discounts Distribution, posting, or copying of this PDF is strictly prohibited without written permission of the National Academies Press. Unless otherwise indicated, all materials in this PDF are copyrighted by the National Academy of Sciences. Request reprint permission for this book Copyright © National Academy of Sciences. All rights reserved. Developing a 21st Century Neuroscience Workforce: Workshop Summary DEVELOPING A 21ST CENTURY NEUROSCIENCE WORKFORCE WORKSHOP SUMMARY Sheena M. Posey Norris, Christopher Palmer, Clare Stroud, and Bruce M. Altevogt, Rapporteurs Forum on Neuroscience and Nervous System Disorders Board on Health Sciences Policy PREPUBLICATION COPY: UNCORRECTED PROOFS Copyright © National Academy of Sciences. All rights reserved. Developing a 21st Century Neuroscience Workforce: Workshop Summary THE NATIONAL ACADEMIES PRESS • 500 Fifth Street, NW • Washington, DC 20001 NOTICE: The workshop that is the subject of this workshop summary was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. -
Bob Eisenberg (More Formally, Robert S
Bob Eisenberg (more formally, Robert S. Eisenberg) Curriculum Vitae September 11, 2021 Maintained with loving care by John Tang, all these years, with thanks from Bob! Address 7320 Lake Street Unit 5 River Forest IL 60305 USA or PO Box 5409 River Forest IL 60305 USA or Department of Physiology & Biophysics Rush University 1750 West Harrison, Room 1519a Jelke Chicago IL 60612 or Dept of Applied Mathematics Room 106D Pritzker Center, corner of State and 31st Street, Illinois Institute of Technology, Chicago IL 60616 Phone numbers Voice: +1 (708) 932 2597; Rush Department: Voice +1 (312)-942-6454; Rush FAX: (312)-942-8711 FAX to email: (801)-504-8665 Skype name: beisenbe Email: [email protected] Other email:[email protected], [email protected], [email protected] Scopus ID’s are 55552198800 and 7102490928. NIH COMMONS name is BEISENBE. ORCID identifier is 0000-0002-4860-5434 Web of Science ResearcherID is: G-8716-2018 and/or P-6070-2019 Publons Public Profile G-8716-2018 Robert S. Eisenberg https://publons.com/researcher/1941224/robert-s-eisenberg/ NIH maintained “My Bibliography: Bob Eisenberg” at http://goo.gl/Z7a2V7 or https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/47999805/?sort=date&direction=ascending Education Elementary School: New Rochelle, New York High School, 1956-59. Horace Mann School, Riverdale, New York City, graduated in three years with honors and awards in Biology, Chemistry, Physics, Mathematics, Latin, English, and History. An interviewer of J.R. Pappenheimer, Professor of Physiology, Harvard Medical School, on American Heart Sponsored television program, ~1957. p. 1 RS Eisenberg September 11, 2021 Undergraduate, 1959-62. -
David H. Hubel 1926–2013
David H. Hubel 1926–2013 A Biographical Memoir by Robert H. Wurtz ©2014 National Academy of Sciences. Any opinions expressed in this memoir are those of the author and do not necessarily reflect the views of the National Academy of Sciences. DAVID HUNTER HUBEL February 27, 1926–September 22, 2013 Elected to the NAS, 1971 David Hunter Hubel was one of the great neuroscientists of the 20th century. His experiments revolutionized our understanding of the brain mechanisms underlying vision. His 25-year collaboration with Torsten N. Wiesel revealed the beautifully ordered activity of single neurons in the visual cortex, how innate and learned factors shape its development, and how these neurons might be assem- bled to ultimately produce vision. Their work ushered in the current era of analyses of neurons at multiple levels of the cerebral cortex that seek to parse out the functional brain circuits underlying behavior. For these achieve- ments, David H. Hubel and Torsten N. Wiesel, along with Roger W. Sperry, shared the Nobel Prize for Physiology or Medicine in 1981. By Robert H. Wurtz Early life: growing up in Canada David Hubel was born on February 27 1926 in Windsor Ontario. Both of his parents were American citizens, born and raised in Detroit, but because he was born in Canada, he also held Canadian citizenship. His father was a chemical engineer, and his parents moved to Windsor because his father had a job with the Windsor Salt company. His mother, Elsie Hubel, was independent minded, with an interest in electricity and a regret that she had not attended college to study it. -
Eric Kandel's Personal Collection.)
IN SEARCH OF MEMORY The Emergence of a New Science of Mind ERIC R. KANDEL Copyright © 2006 ISBN 0-393-05863-8 POUR DENISE CONTENTS Preface xi ONE 1. Personal Memory and the Biology of Memory Storage 3 2. A Childhood in Vienna 12 3. An American Education 33 TWO 4. One Cell at a Time 53 5. The Nerve Cell Speaks 74 6. Conversation Between Nerve Cells 90 7. Simple and Complex Neuronal Systems 103 8. Different Memories, Different Brain Regions 116 9. Searching for an Ideal System to Study Memory 135 10. Neural Analogs of Learning 150 THREE 11. Strengthening Synaptic Connections 165 12. A Center for Neurobiology and Behavior 180 13. Even a Simple Behavior Can Be Modified by Learning 187 14. Synapses Change with Experience 198 15. The Biological Basis of Individuality 208 16. Molecules and Short-Term Memory 221 17. Long-Term Memory 240 18. Memory Genes 247 19. A Dialogue Between Genes and Synapses 201 FOUR 20. A Return to Complex Memory 279 21. Synapses Also Hold Our Fondest Memories 286 22. The Brain's Picture of the External World 295 23. Attention Must Be Paid! 307 FIVE 24. A Little Red Pill 319 25. Mice, Men, and Mental Illness 335 26. A New Way to Treat Mental Illness 352 27. Biology and the Renaissance of Psychoanalytic Thought 363 28. Consciousness 376 SIX 29. Rediscovering Vienna via Stockholm 393 30. Learning from Memory: Prospects 416 Glossary 431 Notes and Sources 453 Acknowledgments 485 Index 489 PREFACE Understanding the human mind in biological terms has emerged as the central challenge for science in the twenty-first century.