John G. Hildebrand
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Layered Reward Signalling Through Octopamine and Dopamine in Drosophila: a Dissertation
University of Massachusetts Medical School eScholarship@UMMS GSBS Dissertations and Theses Graduate School of Biomedical Sciences 2013-05-10 Layered Reward Signalling Through Octopamine and Dopamine in Drosophila: A Dissertation Christopher J. Burke University of Massachusetts Medical School Let us know how access to this document benefits ou.y Follow this and additional works at: https://escholarship.umassmed.edu/gsbs_diss Part of the Neuroscience and Neurobiology Commons Repository Citation Burke CJ. (2013). Layered Reward Signalling Through Octopamine and Dopamine in Drosophila: A Dissertation. GSBS Dissertations and Theses. https://doi.org/10.13028/M2S309. Retrieved from https://escholarship.umassmed.edu/gsbs_diss/657 This material is brought to you by eScholarship@UMMS. It has been accepted for inclusion in GSBS Dissertations and Theses by an authorized administrator of eScholarship@UMMS. For more information, please contact [email protected]. LAYERED REWARD SIGNALLING THROUGH OCTOPAMINE AND DOPAMINE IN DROSOPHILA A Dissertation Presented By Christopher J. Burke Submitted to the Faculty of the University of Massachusetts Graduate School of Biomedical Sciences, Worcester in partial fulfillment of the requirements for the degree of DOCTOR OF PHILOSOPHY Friday, The Tenth of May, 2013 Program in Neuroscience LAYERED REWARD SIGNALLING THROUGH OCTOPAMINE AND DOPAMINE IN DROSOPHILA A Dissertation Presented By Christopher J. Burke The signatures of the Dissertation Defense Committee signifies completion and approval as to style and -
Curriculum Vitae 1/2021
CURRICULUM VITAE 1/2021 John G. Hildebrand Department of Neuroscience Telephone: (520) 621-6626 College of Science, School of Mind, Brain & Behavior Fax: (520) 621-8282 University of Arizona Email: [email protected] PO Box 210077 Website: https://neurosci.arizona.edu/person/john-hildebrand-phd Tucson AZ 85721-0077 Spouse: Gail D. Burd, Ph.D. Education 1964 A.B. Harvard University (Biology – mentors: John Law & Konrad Bloch) 1966 Harvard Medical School, summer training program in general pathology 1969 Ph.D. Rockefeller University (Bio-organic chemistry – mentors: Leonard Spector & Fritz Lipmann) 1969-71 Postdoctoral Fellow, Harvard Medical School, Department of Neurobiology (mentor: Edward Kravitz) 1977 Cold Spring Harbor Laboratory course, Methods in Cellular Neurophysiology 1993 DNA Methods Course, University of Arizona Division of Biotechnology Employment Present Positions 2014-now Foreign Secretary, U.S. National Academy of Sciences 2010-now Honors Professor, University of Arizona 1989-now Regents Professor, University of Arizona 1985-now Professor of Neuroscience, Chemistry & Biochemistry, Ecology & Evolutionary Biology, Entomology, and Molecular & Cellular Biology, University of Arizona Previous Positions 2009-13 founding Head, Dept. of Neuroscience (formerly ARL Div. Neurobiology), Univ. of Arizona 2010-12 Chairman, Executive Committee, UA School of Mind, Brain and Behavior 1986-97 Chairman, UA Committee on Neuroscience, University of Arizona 1985-2009 founding Director, Arizona Research Laboratories Division of Neurobiology, -
The Effects of Serotonin and 5-Carboxamidotryptamine on Aggressive Behavior in Crayfish Pair Interactions
THE EFFECTS OF SEROTONIN AND 5-CARBOXAMIDOTRYPTAMINE ON AGGRESSIVE BEHAVIOR IN CRAYFISH PAIR INTERACTIONS LISA MANGIAMELE Introduction Agonistic interactions between decapod crustaceans consist of a series of bouts characterized by combative use of the claws to strike, grasp, and restrain the opponent. The antennae may also be used as weapons to tap or whip the body of another individual. Fights that escalate in intensity often involve one animal pulling or lifting its opponent above the substrate, and those battles that reach the highest level of intensity may result in individuals attempting to violently break off the appendages of the opponent. These aggressive behaviors are highly stereotyped, and usually interactions result in a clear winner and loser (Bruski and Dunham 1987; Huber and Kravitz 1995). Changes in behavior during these interactions, where winning appears to reinforce aggressive behavior while losing appears to inhibit aggression, aid in the formation of a dominance hierarchy (Issa et al 1999). The neurohormone serotonin [5-hydroxytryptamine (5HT)] has been linked to agonistic behavior and aggressive posturing in lobsters and crayfish (Livingstone et al. 1980; Antonsen and Paul 1997; Huber et al. 1997). Crayfish treated with 5HT show increased intensity of aggressive response to conspecifics, and are more likely to continue fighting in situations that would normally evoke a retreat (Huber et al. 1997). The similarity of this response to the increased aggression exhibited by dominant animals suggests a role for endogenous serotonin in fighting behavior and the maintenance of social status. In addition, amine injection has been found to elicit characteristic postures in the absence of external stimuli. -
Alumni Director Cover Page.Pub
Harvard University Program in Neuroscience History of Enrollment in The Program in Neuroscience July 2018 Updated each July Nicholas Spitzer, M.D./Ph.D. B.A., Harvard College Entered 1966 * Defended May 14, 1969 Advisor: David Poer A Physiological and Histological Invesgaon of the Intercellular Transfer of Small Molecules _____________ Professor of Neurobiology University of California at San Diego Eric Frank, Ph.D. B.A., Reed College Entered 1967 * Defended January 17, 1972 Advisor: Edwin J. Furshpan The Control of Facilitaon at the Neuromuscular Juncon of the Lobster _______________ Professor Emeritus of Physiology Tus University School of Medicine Albert Hudspeth, M.D./Ph.D. B.A., Harvard College Entered 1967 * Defended April 30, 1973 Advisor: David Poer Intercellular Juncons in Epithelia _______________ Professor of Neuroscience The Rockefeller University David Van Essen, Ph.D. B.S., California Instute of Technology Entered 1967 * Defended October 22, 1971 Advisor: John Nicholls Effects of an Electronic Pump on Signaling by Leech Sensory Neurons ______________ Professor of Anatomy and Neurobiology Washington University David Van Essen, Eric Frank, and Albert Hudspeth At the 50th Anniversary celebraon for the creaon of the Harvard Department of Neurobiology October 7, 2016 Richard Mains, Ph.D. Sc.B., M.S., Brown University Entered 1968 * Defended April 24, 1973 Advisor: David Poer Tissue Culture of Dissociated Primary Rat Sympathec Neurons: Studies of Growth, Neurotransmier Metabolism, and Maturaon _______________ Professor of Neuroscience University of Conneccut Health Center Peter MacLeish, Ph.D. B.E.Sc., University of Western Ontario Entered 1969 * Defended December 29, 1976 Advisor: David Poer Synapse Formaon in Cultures of Dissociated Rat Sympathec Neurons Grown on Dissociated Rat Heart Cells _______________ Professor and Director of the Neuroscience Instute Morehouse School of Medicine Peter Sargent, Ph.D. -
Curriculum Vitae RONALD MORGAN HARRIS-WARRICK Professor Section of Neurobiology and Behavior Cornell University Biographical
Curriculum Vitae RONALD MORGAN HARRIS-WARRICK Professor Section of Neurobiology and Behavior Cornell University Biographical Data: Birthplace - Berkeley, California Birthdate - July 28, 1949 Citizenship - U.S.A. Marital status - Married, two children Education: B.A. Biological Sciences, Stanford University, 1970 Ph.D. Genetics, Stanford University School of Medicine, 1976 Thesis advisor: Dr. Joshua Lederberg; Title: "DNA segmentation and sequence heterology in transformation of Bacillus subtilis" Work Experience: 1970-73 Research Assistant, Department of Genetics, Stanford University School of Medicine; Advisor: Dr. Joshua Lederberg 1976-78 NIH Postdoctoral Fellow, Department of Neurobiology, Stanford University, School of Medicine; Advisor: Dr. Eric M. Shooter 1978-80 Muscular Dystrophy Association Postdoctoral Fellow, Department of Neurobiology, Harvard Medical School, Boston, Massachusetts; Advisor: Dr. Edward A. Kravitz 1980-86 Assistant Professor, Section of Neurobiology and Behavior, Cornell University, Ithaca, New York 1986-1992 Associate Professor, Section of Neurobiology and Behavior, Cornell University, Ithaca, New York 1986-87 Visiting Scientist, Laboratoire de Neurobiologie, Ecole Normale Superieure, Paris, France 1988-1991 Associate Chairman, Section of Neurobiology and Behavior, Cornell University, Ithaca, New York 1992-present Professor, Section of Neurobiology and Behavior, Cornell University, Ithaca, New York 1994 Visiting Professor, Department of Molecular and Cellular Physiology, Stanford University School of Medicine -
John G. Hildebrand
CURRICULUM VITAE 8/2014 John G. Hildebrand Department of Neuroscience Telephone: (520) 621-6626 College of Science, School of Mind, Brain & Behavior Fax: (520) 621-8282 University of Arizona Email: [email protected] PO Box 210077 Website: http://neurosci.arizona.edu/user/86 Tucson AZ 85721-0077 Spouse: Gail D. Burd, Ph.D. Education 1964 A.B. Harvard University (Biology – mentors: John Law & Konrad Bloch) 1966 Harvard Medical School, summer training program in general pathology 1969 Ph.D. Rockefeller University (Biochemistry – mentors: Leonard Spector & Fritz Lipmann) 1969-71 Postdoctoral Fellow, Harvard Medical School, Department of Neurobiology (mentor: Edward Kravitz) 1977 Cold Spring Harbor Laboratory course, Methods in Cellular Neurophysiology 1993 DNA Methods Course, University of Arizona Division of Biotechnology Employment Present Positions 2014-18 Foreign Secretary, U.S. National Academy of Sciences 2010-now Honors Professor, University of Arizona 1989-now Regents Professor, University of Arizona 1985-now Professor of Neuroscience, Chemistry & Biochemistry, Ecology & Evolutionary Biology, Entomology, and Molecular & Cellular Biology, University of Arizona Previous Positions 2009-13 founding Head, Dept. of Neuroscience (formerly ARL Div. Neurobiology), Univ. of Arizona 2010-12 Chairman, Executive Committee, UA School of Mind, Brain and Behavior 1986-97 Chairman, UA Committee on Neuroscience, University of Arizona 1985-2009 founding Director, Arizona Research Laboratories Division of Neurobiology, Univ. of Arizona 1981-86 -
Developing a 21St Century Neuroscience Workforce: Workshop Summary
This PDF is available from The National Academies Press at http://www.nap.edu/catalog.php?record_id=21697 Developing a 21st Century Neuroscience Workforce: Workshop Summary ISBN Sheena M. Posey Norris, Christopher Palmer, Clare Stroud, and Bruce M. 978-0-309-36874-2 Altevogt, Rapporteurs; Forum on Neuroscience and Nervous System Disorders; Board on Health Sciences Policy; Institute of Medicine 130 pages 6 x 9 PAPERBACK (2015) Visit the National Academies Press online and register for... Instant access to free PDF downloads of titles from the NATIONAL ACADEMY OF SCIENCES NATIONAL ACADEMY OF ENGINEERING INSTITUTE OF MEDICINE NATIONAL RESEARCH COUNCIL 10% off print titles Custom notification of new releases in your field of interest Special offers and discounts Distribution, posting, or copying of this PDF is strictly prohibited without written permission of the National Academies Press. Unless otherwise indicated, all materials in this PDF are copyrighted by the National Academy of Sciences. Request reprint permission for this book Copyright © National Academy of Sciences. All rights reserved. Developing a 21st Century Neuroscience Workforce: Workshop Summary DEVELOPING A 21ST CENTURY NEUROSCIENCE WORKFORCE WORKSHOP SUMMARY Sheena M. Posey Norris, Christopher Palmer, Clare Stroud, and Bruce M. Altevogt, Rapporteurs Forum on Neuroscience and Nervous System Disorders Board on Health Sciences Policy PREPUBLICATION COPY: UNCORRECTED PROOFS Copyright © National Academy of Sciences. All rights reserved. Developing a 21st Century Neuroscience Workforce: Workshop Summary THE NATIONAL ACADEMIES PRESS • 500 Fifth Street, NW • Washington, DC 20001 NOTICE: The workshop that is the subject of this workshop summary was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. -
Serotonin and Aggression: Insights Gained from a Lobster Model System and Speculations on the Role of Amine Neurons in a Complex Behavior
J Comp Physiol A (2000) 186: 221±238 Ó Springer-Verlag 2000 REVIEW E. A. Kravitz Serotonin and aggression: insights gained from a lobster model system and speculations on the role of amine neurons in a complex behavior Accepted: 27 November 1999 Abstract The amine serotonin has been suggested to well described by other investigators, may be related to play a key role in aggression in many species of animals, the behaviors we are examining. These speculations draw including man. Precisely how the amine functions, heavily from the organizational/activational roles pro- however, has remained a mystery. As with other im- posed for steroid hormones by Phoenix et al. (1959). portant physiological questions, with their large uniquely identi®able neurons, invertebrate systems oer Key words Amine neurons á Aggression á Lobster á special advantages for the study of behavior. In this ar- Neurohormone á Serotonin ticle we illustrate that principal with a description of our studies of the role of serotonin in aggression in a lobster Abbreviations 5,7-DHT 5,7 dihydroxytryptamine á model system. Aggression is a quanti®able behavior in 5HT serotonin á A1 ®rst abdominal ganglion á crustaceans, the amine neuron systems believed to be CHH crustacean hyperglycemic hormone á important in that behavior have been completely map- CNS central nervous system á ped, and key physiological properties of an important EPSPs excitatory post synaptic potentials á subset of these neurons have been de®ned. These results IPSPs inhibitory post-synaptic potentials á are summarized here, including descriptions of the LG lateral giant axon á MG medial giant axon á ``gain-setter'' role and ``autoinhibition'' shown by these OCT octopamine á T5 ®fth thoracic ganglion neurons. -
Modulating Male Aggression and Courtship: Detecting External Pheromonal and Nutritional Information
University of Montana ScholarWorks at University of Montana Graduate Student Theses, Dissertations, & Professional Papers Graduate School 2016 MODULATING MALE AGGRESSION AND COURTSHIP: DETECTING EXTERNAL PHEROMONAL AND NUTRITIONAL INFORMATION Jonathan C. Andrews University of Montana Follow this and additional works at: https://scholarworks.umt.edu/etd Let us know how access to this document benefits ou.y Recommended Citation Andrews, Jonathan C., "MODULATING MALE AGGRESSION AND COURTSHIP: DETECTING EXTERNAL PHEROMONAL AND NUTRITIONAL INFORMATION" (2016). Graduate Student Theses, Dissertations, & Professional Papers. 10931. https://scholarworks.umt.edu/etd/10931 This Dissertation is brought to you for free and open access by the Graduate School at ScholarWorks at University of Montana. It has been accepted for inclusion in Graduate Student Theses, Dissertations, & Professional Papers by an authorized administrator of ScholarWorks at University of Montana. For more information, please contact [email protected]. MODULATING MALE AGGRESSION AND COURTSHIP: DETECTING EXTERNAL PHEROMONAL AND NUTRITIONAL BY JONATHAN ANDREWS B.A. in Human Biology, University of Montana, Missoula 2006 B.A. in Psychology, University of Montana, Missoula (2009) Dissertation/Thesis Presented in partial fulfillment of the requirements for the degree of DOCTOR OF PHILOSOPHY in NEUROSCIENCE The University of Montana Missoula, MT December 2016 Approved by: Sandy Ross, Dean of The Graduate School Graduate School Sarah Certel, Advisor Department of Biological Sciences -
Mary B. Kennedy
BK-SFN-NEUROSCIENCE_V11-200147-Kennedy.indd 104 6/12/20 11:58 AM Mary B. Kennedy BORN: Pontiac, Michigan July 4, 1947 EDUCATION: St. Mary’s College, Notre Dame, IN Johns Hopkins University, Baltimore, MD APPOINTMENTS: Assistant Professor of Biology, California Institute of Technology (1981–1984) Associate Professor, California Institute of Technology (1984–1987) Associate Professor with tenure, California Institute of Technology (1987–1992) Professor of Biology, California Institute of Technology (1992–2002) Allen and Lenabelle Davis Professor of Biology, California Institute of Technology (2002–2020) Director of the Moore Center for Integrative Study of Cell Regulation, California Institute of Technology (2006–2012) HONORS AND AWARDS (SELECTED): McKnight Neuroscience Development Award (1984) Faculty Award for Women Scientists and Engineers, National Science Foundation (1991) Fellow of the American Association for the Advancement of Science (1991) Javits Neuroscience Investigator Award, National Institutes of Health (1992) Fellow of The American Academy of Arts and Sciences (2002) Fondation Ipsen Prize in Neuronal Plasticity (2006) Mary Kennedy is a pioneer in the elucidation of biochemical mechanisms underlying learning and memory. She was trained in traditional biochemistry, studying lipid metabolism in bacteria. After receiving her degree, she moved into the study of biochemical regulation in the nervous system and for the past 40 years, has studied control of synaptic plasticity in the postsynaptic spines of glutamatergic synapses. She first purified and studied calcium/calmodulin-dependent protein kinase II (CaMKII), showing that it is highly concentrated in the brain, particularly in the postsynaptic density, and becomes calcium- independent upon autophosphorylation, resulting in switch-like enzymatic behavior. She showed that CaMKII is a major target of calcium ion entering through N-methyl-D-aspartate (NMDA)-type glutamate receptors during induction of long-term potentiation. -
Curriculum Vitae RONALD MORGAN HARRIS-WARRICK William T
Curriculum Vitae RONALD MORGAN HARRIS-WARRICK William T. Keeton Professor in Biological Sciences Department of Neurobiology and Behavior Cornell University Biographical Data: Birthplace - Berkeley, California Birthdate - July 28, 1949 Citizenship - U.S.A. Marital status - Married, two children Education: B.A. Biological Sciences, Stanford University, 1970 Ph.D. Genetics, Stanford University School of Medicine, 1976 Thesis advisor: Dr. Joshua Lederberg; Title: "DNA segmentation and sequence heterology in transformation of Bacillus subtilis" Work Experience: 1970-73 Research Assistant, Department of Genetics, Stanford University School of Medicine; Advisor: Dr. Joshua Lederberg 1976-78 NIH Postdoctoral Fellow, Department of Neurobiology, Stanford University, School of Medicine; Advisor: Dr. Eric M. Shooter 1978-80 Muscular Dystrophy Association Postdoctoral Fellow, Department of Neurobiology, Harvard Medical School, Boston, Massachusetts; Advisor: Dr. Edward A. Kravitz 1980-86 Assistant Professor, Section of Neurobiology and Behavior, Cornell University, Ithaca, New York 1986-1992 Associate Professor, Section of Neurobiology and Behavior, Cornell University, Ithaca, New York 1986-87 Visiting Scientist, Laboratoire de Neurobiologie, Ecole Normale Superieure, Paris, France 1988-1991 Associate Chairman, Section of Neurobiology and Behavior, Cornell University, Ithaca, New York 1992-present Professor, Department of Neurobiology and Behavior, Cornell University, Ithaca, New York 1994 Visiting Professor, Department of Molecular and Cellular Physiology, -
Harvard University Program in Neuroscience
Harvard University Program in Neuroscience History of Enrollment in The Program in Neuroscience July 2016 Updated each July Nicholas Spitzer, M.D./Ph.D. B.A., Harvard College Entered 1966 * Defended May 14, 1969 Advisor: David Poer A Physiological and Histological Invesgaon of the Intercellular Transfer of Small Molecules _____________ Professor of Neurobiology University of California at San Diego Eric Frank, Ph.D. B.A., Reed College Entered 1967 * Defended January 17, 1972 Advisor: Edwin J. Furshpan The Control of Facilitaon at the Neuromuscular Juncon of the Lobster _______________ Professor Emeritus of Physiology Tus University School of Medicine Albert Hudspeth, M.D./Ph.D. B.A., Harvard College Entered 1967 * Defended April 30, 1973 Advisor: David Poer Intercellular Juncons in Epithelia _______________ Professor of Neuroscience The Rockefeller University David Van Essen, Ph.D. B.S., California Instute of Technology Entered 1967 * Defended October 22, 1971 Advisor: John Nicholls Effects of an Electronic Pump on Signaling by Leech Sensory Neurons ______________ Professor of Anatomy and Neurobiology Washington University Richard Mains, Ph.D. Sc.B., M.S., Brown University Entered 1968 * Defended April 24, 1973 Advisor: David Poer Tissue Culture of Dissociated Primary Rat Sympathec Neurons: Studies of Growth, Neurotransmier Metabolism, and Maturaon _______________ Professor of Neuroscience University of Conneccut Health Center Peter MacLeish, Ph.D. B.E.Sc., University of Western Ontario Entered 1969 * Defended December 29, 1976 Advisor: David Poer Synapse Formaon in Cultures of Dissociated Rat Sympathec Neurons Grown on Dissociated Rat Heart Cells _______________ Professor and Director of the Neuroscience Instute Morehouse School of Medicine Peter Sargent, Ph.D.