About the Cover:

Laboratory Directed Research and Development 2010 proj- ects depicted on the back and front covers (left to right): “New Algorithms to Scale Domain Decomposition Up to BlueGene Architectures,” David Hysom (08-ERD-014); “Strain-Rate Effects on Plasticity and Defects,” James Hawreliak (08-ERD-033); “High- Temperature Thermal X-Radiation Sources at Short-Pulse ,” Marilyn Schneider (08-ERD-024); “Collection of Refractory Debris from the National Ignition Facility for Stewardship- Relevant Measurements,” Dawn Shaughnessy (09-ERD-026); “The Advance of Uncertainty Quantification Science,” Richard Klein (10-SI-013); “Precision Mono-Energetic Gamma-Ray Science for NNSA Missions,” Christopher Barty (09-SI-004); “Advanced Computational and Experimental Analysis of Plasma Equations of State and Transport,” Brian Wilson (08-ERD-027); “Advanced Rare-Event Detectors for Nuclear Science and Security,” Adam Bernstein (10-SI-015); “Coupling Advanced Cryo-Electron Microscopy with High-Performance Computing to Resolve Biomolecular Function,” Felice Lightstone (09-ERD-009); and “Modern Finite Elements for Lagrangian Hydrodynamics,” Tzanio Kolev (09-ERD-034).

UCRL-TR-113717-10 Disclaimer Available to DOE and DOE contractors from the Office of Scientific and Technical Information This document was prepared as an account of work spon- P.O. Box 62 sored by an agency of the United States Government. Neither Oak Ridge, TN 37831 the United States Government, Lawrence Livermore National Security, LLC, nor any of their employees, makes any warranty, Prices available from (423) 576-8401 express or implied, or assumes any legal liability or responsibility http://www.osti.gov/bridge/ for the accuracy, completeness, or usefulness of any information, apparatus, product, or process disclosed, or represents that its use Available to the public from the would not infringe privately owned rights. Reference herein to any National Technical Information Service specific commercial products, process, or service by trade name, U.S. Department of Commerce trademark, manufacturer, or otherwise, does not necessarily 5285 Port Royal Rd. constitute or imply its endorsement, recommendation, or favoring Springfield, VA 22161 by the United States Government or Lawrence Livermore National http://www.ntis.gov/ Security, LLC. The views and opinions of authors expressed herein do not necessarily state or reflect those of the United States or Government or Lawrence Livermore National Security, LLC, and shall not be used for advertising or product endorsement Lawrence Livermore National Laboratory purposes. Technical Information Department Digital Library This work was performed under the auspices of the U.S. https://library-ext.llnl.gov/ Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344. Acknowledgments

The Laboratory Directed Research and Development Program extends its sincere appreciation to the principal investigators of fiscal year 2010 projects for providing the content of the annual report and to the publications team. The program also thanks the following members of the Institutional Science and Technology Office for their many contributions to this publication: Barbara Jackson, administrator; Nancy Campos, database manager; Steve McNamara, computer specialist; and Kristen Croteau, resource manager. We extend particular thanks to Judith Kammeraad, who successfully directed the LDRD Program in 2010, as well as for the two previous years.

Scientific Editors: Kenneth Jackson, Paul Chrzanowski, Rob Sharpe

Publication Editors: Jeffrey Sketchley, Paul Kotta

Proofreader: Karen Kline

Publication Designer: Lucy Dobson Acknowledgments

LDRD FY10 ANNUAL REPORT i Director’s Statement

The Laboratory Directed Research and Development (LDRD) Program, authorized by Congress in 1991 and administered by the Institutional Science and Technology Office at Lawrence Livermore, is our prima