5.3 Student Safety, Wellness and Health Policies and Procedures

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5.3 Student Safety, Wellness and Health Policies and Procedures:

Physical HealthCare Services

Students on each campus are provided with a list of medical care facilities that are easily accessible to PCOM's campuses. The list of physicians, clinics, health care centers and hospitals is posted in the Student Handbook, on line on PCOM’s intranet (MyPCOM) and is also available in the Office of Student Affairs. Health records and inoculations/vaccinations required for enrollment in the DO program are managed by the Student Wellness Center. Flu shots are also provided. The PCOM Student Health Services model provides triage and referral for students (not student families) for acute physical and mental health problems. Students are referred to contracted providers for treatment. The Georgia and South Georgia Campuses have established relationships with physical and mental health providers to serve as providers of student health services to PCOM students. Through the MyPCOM Student Resources Tab all students can access a listing of both medical and psychiatric providers from on campus or off campus at all times.

The charge for treatment, labs, blood work, X-ray, etc. which are ordered is submitted to the student’s health insurance company for payment; charges not covered by insurance are the responsibility of the student. The student must show his or her medical insurance card at all visits, including Student Health provider office visits. For treatment in any Emergency Room, bills are sent to the student for all services provided. These bills are subsequently submitted to insurance for payment. For their protection, every PCOM student is required to carry insurance and encouraged to maintain a personal, local, primary care physician for preventive medicine and other routine health care.

PCOM requires that all students have health insurance and offers a group health insurance plan to its students, Health insurance coverage under this plan will end either when the student withdraws from school, takes a leave of absence without making special arrangements with the Bursar to pay premiums for coverage to continue, cancels during the “open enrollment” period by providing evidence of alternative comparable coverage or presents evidence of comparable insurance through another or on August 1 of the graduation year. Graduates may elect to end student group insurance earlier provided insurance from internship institution or other employer goes into effect; graduates may extend insurance for up to three months beyond August 1 by making special arrangements with the Office of Student Affairs.

HEALTH INSURANCE POLICY PCOM requires all students to be covered by health insurance. HEALTH SERVICES Students choosing to use any of PCOM’s affiliated health care services (either located on or off campus) must follow the same payment- for- service policies that are required of patients from the external community who utilize PCOM health care services. The medical practices accept most major insurance plans but must follow each plan equally for all patients. Please be sure to understand completely the specifics of your individual health insurance plan. WELLNESS SERVICES If you are on the Philadelphia Campus and not feeling well and would like to be seen by a physician affiliated with PCOM, feel free to contact the PCOM Family Medicine Office, located on the first floor of Rowland Hall to make an appointment. The phone number is (215) 871- 6380. Be sure to let the staff person know you are a PCOM student. You will be required to bring your medical insurance card with you to the appointment (this is not a free service). Georgia students please note the locations below. If you are feeling ill after hours or on the weekend and are in need of emergency services, you should go to the nearest hospital. RESOURCES AT OR NEAR THE CAMPUS PA Campus Lankenau Hospital at 100 Lancaster Avenue, Wynnewood, PA Phn: 610-658-6003 GA Campus Strickland Family Medicine Center at 665 Duluth Highway, Lawrenceville, GA Phn: 678-312-0400 South GA Campus Sterling Group Primary Care Clinic 6 Hospital Park, Moultrie, GA Phn: 229-985-3320 For additional resources on and off campus in both Pennsylvania and Georgia, please see the listing of physical health resources and hours on pcom.edu. INJURY DURING TRAINING ASSIGNMENTS In the event of an accident, injury, or other incident during a training assignment, the accident report procedure for the institution where the student is training must be followed. Without this record keeping, the student’s own health insurance coverage and/or PCOM's professional liability could be placed in jeopardy. In the event of an injury in a clinical or other training setting, such as a needle stick or splash, the student should report the incident to the supervisor of the clerkship and also to the Office of Student/Resident Medical Records immediately by calling 215-871-6420. The student is responsible for the cost of evaluating and treating the injury. The student’s personal health insurance plan will be billed by the provider. Students are responsible for all additional co-pays. Information about procedures relating to radiation and hazardous material exposures at training sites is contained on the PCOM website and in the institutional Health and Safety Manual. VACCINATIONS All students are required to complete all necessary health/physical examination forms and to have all immunizations and health-related records completed by the deadlines set by the Office of Student Wellness. Vaccinations are required, upon initial enrollment, for all students who have contact with patients, clients, school students or whose program requires laboratory instruction. Psychology students must document immunizations prior to the clinical component of the academic program. Students in the Organizational Development and Leadership programs are not required to document immunizations. Philadelphia College of Osteopathic Medicine Page 1 of 3 Policy and Procedure - Influenza Vaccination

Prepared by: Human Resources Approved by: }JJ-�� Effective Date: September 1, 2016 Revision Date: September 1, 2019

Title: Influenza Vaccination 2016 Policy: 2.90

Policy: Philadelphia College of Osteopathic Medicine requires influenza immunization on an annual basis for all personnel working or volunteering within a PCOM healthcare provider facility/department.

Purpose: The purpose of this policy is to protect patients, employees, family members and the community from influenza infection through annual immunization of all PCOM faculty, staff, students/trainees in clinical settings, clinical research personnel, contracted personnel who work in patient care areas, volunteers and persons with professional staff privileges or credentials.

Scope: For purposes of this policy, PCOM includes all healthcare centers and clinical sites on all campuses in Philadelphia and Georgia.

Procedures:

All Healthcare managers and supervisors are responsible for the enforcement of this policy requiring influenza immunization on an annual basis unless exemption has been granted as described below:

A. Annual Influenza Immunization:

1. All faculty and staff working in a PCOM health care provider facility must be immunized against influenza each year. This includes all personnel as defined under the scope and purpose of this policy.

2. Influenza vaccine is available free of charge to all PCOM employees.

The vaccination program is coordinated through the Wellness Program.

3. If faculty and staff and personnel covered by this policy are vaccinated through services other than PCOM (i.e. private physician office, public clinics) they must provide proof of immunization to their respective departments. Proof of immunization may include a physician's note, a receipt, or copy of consent.

B. Infection Control Procedures:

1. All personnel will be required to strictly adhere to respiratory hygiene and hand hygiene practices, as well as isolation precautions. Student Wellness Center Most Commonly asked Questions 1. What does “quantitative results” mean?

Quantitative lab results mean that the mandatory blood work (Hepatitis B, Rubella, Rubeola (Measles), Mumps, and Varicella) need a numeric value as a result.

2. Where can I get a discount lab slip from and where do I get blood work done on campus?

Philadelphia students contact Monica Jones at 215-871-6420 PCOM Georgia and South Georgia students contact Barri Dean at 678-225-7484 3. What is the two-step PPD procedure?

The two-step PPD procedure involves getting a PPD placed and getting it read 48-72 hours later (this is the first step). Two weeks later, you repeat the PPD placement and reading (second step). You will only need to get Two Step if required by affiliate.

4. If I do not have my childhood vaccine dates for (polio, Tdap or Varicella, can lab work act as a substitute?)

If you are unable to retrieve your childhood vaccines, you can get the titers needed to show immunity. This is very common with childhood polio vaccines.

5. If I need to get an updated vaccine (Hep B, MMR, Varicella, or TDAP) on campus, where can I go?

Philadelphia students contact Monica Jones at 215—871-6420

PCOM Georgia and South Georgia students contact Barri Dean at 678-225-7484

6. What is the Hep B waiver?

PCOM honors this waiver in the event of your Hep B results being negative or if you are unable to finish your series. If you complete the series and get a titer that is positive, the waiver is voided out.

7. What if I have a positive PPD reading?

You have to get a chest x-ray. A chest x-ray can be updated every2 to 3 years. 8. What is the difference between vaccines and blood titers?

Vaccines are given if blood work or titers come back with negative results. For example “If mumps is negative, you will need a MMR booster vaccine and the same with a Hep B, Varicella new vaccine are required and new lab work.

Can I have a PPD skin test done in Student Wellness and what’s the cost? Yes all Annual PPD and 2 step PPD are done in Student Wellness 9. Center A) Philadelphia students call Monica Jones 215-871-64 Georgia and South Georgia students B) 20 Can student call wellness Barri Dean provide at 678- lab225-7484 slip for Drug screen test? Each PCOM program has different requirements; you will need to ontact 10. student wellness for more information. A) c

Monica L. Jones

Coordinator of Student Wellness Center PCOM BLOODBORNE PATHOGEN INJURY PROCEDURE FOR STUDENTS

NEEDLE STICK/SPLASH

HOSPITAL SETTING The student is to follow the policy of that institution by:

1-going to the E.R. for immediate care (i.e. wound care PEP,labs) OR 2-going to Emp.Health Dept. /OHS of the institution for immediate care during normal work hours.

OFFICE SETTING At the time of a BLOODBORNE Pathogen injury, students should be given Immediate care, i.e.wound care, PEP, lab testing for him/herself.The”source”patient will have lab testing done in accordance with that State’s laws.

(Lab testing for PCOM students and “source” patient will include but NOT be limited to HIV, Hepatitis BS Ab, Hepatitis C Ab and any other lab deemed appropriate should PEP [Post exposure Prophylaxis] be recommended).

In all cases, Student Wellness should be notified of the injury<72 hrs.at (215)871-6420. In all cases a copy of incident report and lab work should be faxed to 215-871-6309

BILLING/GUARANTOR INFORMATION All fees related to the injury will be the responsibility of: Student’s Personal Health Insurance Students will be responsible for all additional co-pays.

______Sr.Vice President of Academic Affairs/Dean OFFICIAL COLLEGE POLICY

POLICY # 6.00 Policy Name: Formaldehyde Policy for PCOM Pregnant Individuals

Responsible Department: Occupational and Environmental Safety Effective Date: August 30, 2018 Last Revision: December 3, 2018

I. SCOPE:

It is the policy of the Philadelphia College of Osteopathic Medicine in coordination with the Occupational and Environmental Safety Department to provide the College community with a safe environment. The primary goal of the Formaldehyde Policy for PCOM Pregnant Individuals is to minimize employee and student exposure to formaldehyde. Formaldehyde is a colorless and flammable organic chemical with a strong odor. Formaldehyde is mixed in stock bottles of 37% to 40% to be used as a preservative and disinfectant. Formalin is a diluted stock, typically 3.7% to 4.0%. Formaldehyde is a potential human carcinogen. Exposure routes of formaldehyde can occur through inhalation, skin and eye contact. The target organs for formaldehyde are the skin, eyes and respiratory system. Pregnant PCOM individuals shall take extra precautions when working in areas where there is potential exposure to formaldehyde. These precautions include wearing appropriate personal protective equipment (PPE) such as respirators.

II. POLICY STATEMENT:

The purpose of this policy is to mitigate formaldehyde exposure for pregnant individuals by identifying a process to limit exposure and provide safety equipment.

HEALTH EFFECTS AND RISKS

 According to the National Cancer Institute, researchers have concluded that based on data from studies in people and from lab research, exposure to formaldehyde may cause leukemia in humans. Chronic exposure to formaldehyde and its solutions have been associated with cancers of the lung and nasal passageways as well.  Formaldehyde can irritate the eyes, nose, throat and respiratory system.  Exposure to formaldehyde can cause lacrimation and wheezing. Working with formaldehyde may increase chances of having fertility problems, birth defects or a miscarriage. Most work exposures to formaldehyde are unlikely to be high enough to enter breast milk. However, formaldehyde may enter breast milk at exposure levels that are found in some workplaces, such as anatomy and mortuary science laboratories. Formaldehyde has been shown to be teratogenic in laboratory animals but human studies have been inconclusive. A teratogen is an agent or factor than can disturb the development of an embryo or fetus. Limiting Exposure to Formaldehyde

 Limit exposure to formaldehyde as much as possible. Wear gloves, lab coats, and safety glasses to prevent contamination of skin or clothing. Wash hands at end of class or your shift.

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 Avoid contamination of personal items. Store bags and purses in the lockers provided. Use book stands attached to cadaver tables to hold dissection guides. Do not bring food or drink into the lab.  Suction excess fluids from the chest cavity with supplied basters. Do not allow formaldehyde containing liquids to puddle on the floor. Use absorbent pads to absorb formaldehyde.  Properly cover the cadaver after you finish. This will reduce the release of formaldehyde into the cadaver lab.  When not working with formaldehyde, avoid areas where formaldehyde is in use.  Avoid loitering and eating near areas where formaldehyde is present.

III. RESPONSIBILITY

All faculty, staff and students engaged in the use or handling of formaldehyde (including dissection of embalmed cadavers) are responsible for understanding all hazards associated with its use, and for using appropriate work practices, engineering controls and PPE.

The Principal Investigator (PI) or faculty member is responsible for confirming that his/her staff and students has been trained in the safe use and handling of formaldehyde. Use of formaldehyde is restricted to the specific staff members who have had training in proper use, handling and storage.

The Federal Pregnancy Discrimination Act

The Federal Pregnancy Discrimination Act prevents an institution from compelling a woman to disclose that she is pregnant, and it prevents her from being assigned to different tasks simply because she is pregnant. If a woman willingly informs the institution that she is pregnant then additional assessments, precautions or other accommodations can be implemented. Programs, departments and faculty will determine the extent to which a pregnant lab worker or lab student can be excused from lab requirements or what accommodations can be made.

What Can Be Done to Reduce or Eliminate Exposure While Pregnant

 If you are pregnant, become pregnant, or are breastfeeding and are working with formaldehyde or formaldehyde solutions, you must wear a respirator. Pregnant employees and students are only exempt from wearing a respirator if they receive a written recommendation from their physician indicating so.  Protect yourself by talking to your supervisor, faculty member or safety officer to find out the formaldehyde exposure levels in your workplace, and make sure that exposure limits are being followed.

o There is evidence that formaldehyde levels higher than 2 ppm can enter the milk of animals, but we do not know how likely this is for humans.

 These exposure limits were written for healthy non-pregnant workers, and might not protect an unborn baby. Consider talking to your supervisor, faculty member or safety

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officer about avoiding duties with formaldehyde exposure on a temporary basis during pregnancy.

 If you cannot avoid formaldehyde exposure during pregnancy or breastfeeding:

o Respirators are protective masks or hoods that you can wear to help you breathe cleaner air. There are many different types of respirators. PCOM provides half facepiece reusable respirators with formaldehyde/organic vapor cartridges. Many respirators are unlikely to cause difficulties for pregnant workers, but there are a few things to consider: . Some respirators must be fitted to your face to make a tight seal. Weight changes, including weight gained during pregnancy, can affect how a respirator fits. If a respirator does not fit correctly, it may not protect you. . Some respirators (like negative pressure respirators) make you work harder to breathe. Because pregnancy can also make women work harder to breathe, this can sometimes cause difficulties (particularly late in pregnancy).

If you wear a tight-fitting or negative pressure respirator, you should talk to your doctor and safety officer to make sure you can wear your respirator safely and correctly throughout pregnancy. Pregnant women who have difficulty with their normal respirators might be able to switch job duties temporarily so they don’t have to wear a respirator, or switch to a different kind of respirator, such as a powered air-purifying respirator (PAPR).

o Wear appropriate gloves when handling formaldehyde. Formaldehyde and other solvents can be absorbed through the skin. Formaldehyde can break through some of the most common types of gloves in 15 minutes or less. Gloves made from butyl rubber, neoprene rubber, or nitrile rubber are generally recommended. Latex rubber, natural rubber, polyethylene, or polyvinyl alcohol gloves are not recommended because they do not offer adequate protection against formaldehyde. Some chemicals can pass through, or permeate, gloves or other PPE very quickly. The companies that sell gloves and other PPE have chemical resistance guides that show how long a specific glove type or fabric will hold up to specific chemicals. Work with PCOM’s safety office to find the right gloves and other PPE. o If exposure cannot be avoided during pregnancy, respirators shall be worn to reduce the amount of certain chemicals that workers breathe in. Charcoal masks or surgical masks will not protect you from these chemicals. To be effective, respirators must be used correctly. o Wear safety glasses and lab coats. o Wash any formaldehyde off your skin and change your clothes after work. o Clean drips and spills quickly using formaldehyde neutralization pads or sheets. o Some activities will have higher exposures than others. For example, dissections of the chest and abdomen appear to have higher levels of formaldehyde exposure. o Remove formaldehyde-contaminated waste from the work area at the end of the anatomy course.

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Respiratory FIT Testing Information for Pregnant Individuals

If a student is pregnant, the student must wear a respirator.

For Philadelphia Campus Students:

For more information on FIT testing for respirator use, please contact the Occupational and Environmental Safety Department located at Rowland Hall, Suite 417. Additionally, the Occupational and Environmental Safety Department can be reached at (215) 871-6360 and (215) 871-6150 or by email at [email protected].

For Georgia Campus Students:

For more information on FIT testing for respirator use, please contact the Director of the Simulation Center (Suite 112), by telephone at (678) 225-7475.

For PCOM South Georgia Students:

For more information on FIT testing for respirator use, please contact the Director of the Simulation Center by telephone at 229-668-3110

For Philadelphia and Georgia Employees:

If an employee is pregnant, the employee must wear a respirator.

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Philadelphia College of Osteopathic Medicine

PCOM Philadelphia PCOM Georgia PCOM South Georgia

MEDICAL STUDENT DUTY HOURS AND FATIGUE MITIGATION

The accreditation standards for graduate medical education programs include restrictions on the duty hours of residents. Additionally, institutions are expected to promote a clinical learning environment in which duty hours are monitored and strategies exist to mitigate the effects of fatigue.

This policy is established to prepare PCOM students for the clinical schedules of clerkship and to address the impact of academic or clinical workload on medical student well‐being.

1. The goals of this policy are to:

a. Promote medical student understanding of duty hour restrictions, the rationale behind them, and the importance of adherence. b. Ensure that students receive information and education on fatigue, sleep deprivation, burnout, and other issues related to physical and psychological well‐being. c. Ensure that students receive education on fatigue management and mitigation strategies, as well as other ways to promote well‐being. d. Provide guidance as to duty hours on clerkship rotations

1. Education

a. PCOM students will receive information and education regarding the impact of sleep deprivation and fatigue, and strategies to better manage and mitigate these effects. b. Resources will be made available on fatigue and other mental health and well‐being topics throughout the curriculum. c. Prior to entering clerkship, PCOM students will receive information about duty hour restrictions that are associated with residency training programs and expectations for student work hours on clerkship rotations.

2. Medical student hours on clinical rotations

a. During clerkship, a student’s work schedule will be dependent upon their rotation assignment. Students should seek clarification of their schedule if there is any uncertainty about duty hours. b. Students may be scheduled for night and/or weekend shifts based on the work flow of the assigned rotation. Such assignments should be balanced to promoted the student’s education over service. c. While assigned clinical duties, rounds, and on‐site educational programs are considered part of the student’s work hours, activities such as independent study, reading for assignments, and preparing for COMAT examinations are not and should not be included in a tally of work hours. d. Students should be assigned to no more than 80 hours per week and should have at least one day off in every seven‐day period or two consecutive days of in every fourteen‐day period. Students who are scheduled for in‐house overnight call should be permitted to go home after eighteen to twenty‐four hours, and should not be scheduled more frequently than every third night. e. Students should have access to on‐site call room facilities if scheduled for overnight call in a hospital setting. f. Students will be expected to self‐monitor their assigned hours. If a student believes that he or she is being asked to exceed these duty hours during any clerkship rotation, he/she should immediately consult the Office of Undergraduate Clinical Education at the student’s home campus. All other matters related to duty hours should also be directed to the Office of Undergraduate Clinical Education at the student’s home campus.

Behavioral Wellness and Fatigue Mitigation Policies for PCOM Interns, Residents and Fellows (excerpted from 2018-19 PCOM Postgraduate Education Policy Manual)

Counseling, Medical and Psychological Support Services

If a Resident requires counseling, medical and or psychological support services the following procedure should be used:

1. Contact the Associate Dean for Graduate Medical Education, Supervisor or the Executive Director of PCOM MEDNet at 215-871-6690.

2. Counseling services will be provided by Carebridge 1-800-437-0911.

Learning and Working Environment (Duty Hours) The Institutional GMEC ensures that all GME programs are in compliance with the Accreditation Council for Graduate Medical Education requirements to monitor and limit resident duty hours and work environment. The GMEC recognizes that duty hours and work environment must be carefully planned and monitored to ensure sound academic and clinical education, patient safety, and resident well-being. The GMEC further ensures that each GME program establishes formal written policies governing resident duty hours.

Maximum Hours of Work per Week o Duty hours must be limited to 80 hours per week, averaged over a four week period, inclusive of all in-house call activities and all moonlighting.

Maximum Duty Period Length o Clinical and Educational work periods for residents must not exceed 24 hours or continuous, scheduled clinical assignments. o Up to 4 hours of additional time may be used for activities related to patient safety, such as providing effective transitions of care and/or resident education. o Resident physicians must not be assigned additional clinical responsibilities after 24 hours of continuous in-house duty. o In unusual circumstances, Resident physicians, on their own initiative, may remain beyond their scheduled period of duty to continue to provide care to a single patient. Justifications for such extensions of duty are limited to reasons of required continuity for a severely ill or unstable patient, academic importance of the events transpiring, or humanistic attention to the needs of a patient or family. Under those circumstances, the resident must: o Appropriately hand over the care of all other patients to the team responsible for their continuing care; and document the reasons for remaining to care for the patient in question and submit that documentation in every circumstance to the program director/DIO. o The program director must review each submission of additional service and track both individual resident and program-wide episodes of additional duty. o Programs must encourage resident physicians to use alertness management strategies in the context of patient care responsibilities.

Maximum In-House On-Call Frequency

Resident physicians must be scheduled for in-house call no more frequently than every third-night (when averaged over a four-week period).

Minimum Time Off Between Scheduled Duty Periods o Resident physicians (as defined by the Review Committee) should have 10 hours free of duty and must have 8 hours off between scheduled duty periods. They must have at least 14 hours free of duty after 24 hours of in-house call. o Resident physicians in the final years of education (as defined by the Review Committee) must be prepared to enter the unsupervised practice of medicine and care for patients over irregular or extended periods. o This preparation must occur within the context of the 80-hour, maximum duty period length, and one-day-off-in seven standards. While it is desirable that resident physicians in their final years of education have eight hours free of duty between scheduled duty periods, there may be circumstances (as defined by the Review Committee) when these resident physicians must stay on duty to care for their patients or return to the hospital with fewer than eight hours free of duty. o Circumstances of return-to-hospital activities with fewer than eight hours away from the hospital by resident physicians in their final years of education must be monitored by the program director/DIO.

Maximum Frequency of In-House Night Float

Resident physicians must not be scheduled for more than six consecutive nights of night float. (The maximum number of consecutive weeks of night float, and maximum number of months of night float per year may be further specified by the Review Committee).

Mandatory Free Time off of Duty

Resident physicians must be scheduled for a minimum of one day in seven free of duty every week (when averaged over four weeks). At-home call cannot be assigned on these free days.

Duty Hour Exceptions o The Program Director must follow the duty hour exception policy from the ACGME/AOA Manual on Policies and Procedures. o Exceptions that occur or granted are to be reported as a duty hour exception at the next GMEC meeting.

At-Home Call o Time spent in the hospital by resident physicians while on at-home call must count towards the 80-hour maximum weekly hour limit. The frequency of at-home call is not subject to the every-third-night limitation, and should not exceed every other night, but must satisfy the requirement for one-day-in-seven free of duty, when averaged over four weeks. o At-home call must not be as frequent or taxing as to preclude rest or reasonable personal time for each resident. o Resident physicians are permitted to return to the hospital while on at-home call to care for new or established patients. Each episode of this type of care, while it must be included in the 80-hour weekly maximum, will not initiate a new “off-duty period.”

The GMEC will require all programs to assess compliance to their duty hour policy on a weekly basis. Quarterly, each program will report to the Institutional GMEC documenting compliance to the duty hour policy.

Duty Hour Violations PCOM, the Sponsoring Institution, takes the ACGME’s policies very seriously since infractions could jeopardize patient safety, the institution’s accreditation status, and ultimately the accreditation status of all their programs. Therefore, any resident who knowingly violates the Duty Hour Policy will be dealt with by the respective Program Director. If a resident knowingly continues to violate the Duty Hour Policy, the Program Director/DIO can invoke other departmental sanctions and at any time may bring the issue before the GMEC for review and possible subsequent disciplinary action up to and including the resident’s dismissal from the program.

Time Sheets All trainees are required to document their duty hours each week in E-Value.

PCOM Health and Wellness There are added-value benefits available in order to ensure the health and wellness of you and your family. Work Life Services and Employee Assistance Program (EAP) PCOM is pleased to provide you with Work Life Services and an Employee Assistance Program though Carebridge Corporation. These services provide confidential consultations to help you successfully manage life’s challenges. Carebridge’s certified counselors are available 24/7 via face-to-face meetings or through convenient telephone consultations to assist you with issues such as: Health Advocate  Marital/family/parenting relationships Health Advocate is the leading health care advocacy and  Alcohol/drug problems assistance program nationwide. This benefit is available to you, your spouse, dependent children, parents and parents  Stress Management and fatigue mitigation -in-law. Health Advocate assists with services ranging from health care and insurance-related issues to providing one-on-  Depression and anxiety; grief and loss one support for improving your health and well-being.  Financial pressures Registered nurses, medical directors and benefits and claims specialists are available to help give you peace of mind in  Spousal/child/parent abuse navigating the health care system. Speak to a Health Advocate representative to:  Smoking cessation  Find the best doctors, dentist, hospitals, other health care  Locating child care providers providers anywhere in the country. To receive services, you will need to use code R5SAF. The  Expedite appointments including hard-to-reach code will be needed to register online via the Carebridge specialists; arranges for specialized treatments and tests. website ( www.myliferesource.com ) or when contacting the consultants on the telephone  Help resolve insurance claims; negotiate billing or (1-800-437-0911) payment arrangements.  Assist with eldercare such as finding adult daycare, assisted living and other related issues facing parents, Wellness Coaches USA parents-in-law. Wellness Coaches are available with expanded hours to  Obtain unbiased health information about complex provide confidential Personal Health Risk coaching directly in medical conditions to help you make informed decisions. your workplace. Your wellness coach is a certified wellness professional who can answer questions and offer coaching in  Assist in the transfer of medical records such as x-rays areas such as: and lab results.  Work with insurance companies to obtain appropriate  Exercise and fitness approvals for needed services.  Tobacco cessation  Help you make informed decisions with researching conditions and treatment options, and facilitate second  Stress Management and fatigue mitigation opinions.  Nutrition To reach a Health Advocate professional, call 1-866-695-  High blood pressure/heart disease 8622 or visit the website at www.HealthAdvocate.com for more information. Health Advocate can be accessed 24  Diabetes and sleep hours a day, 7 days a week. Normal business hours are Monday – Friday between 8 am and 9 pm EST. After hours They can also perform health metric testing for blood and during weekends, on call staff is always available for pressure, body composition and hydration, or assist with assistance with issues that need to be addressed during non- management of minor aches, pains or muscle soreness. business work hours. Allyson Heller (PA Campus) Please Note: Health Advocate does not replace medical 1-484-730-1944; [email protected] coverage. Joe Threats (GA Campus) 1-866-894-1300, ext. 180; [email protected]

16 IBC Health & Wellness Programs Once you are enrolled in a PCOM medical plan, there are additional benefits available to you and your eligible dependent(s) that are designed to encourage healthy behaviors. Exclusive discounts are also available on products and services to help improve your health and save you money. You must register to take advantage of these benefits by calling 800-ASK-BLUE or visiting the website at www.ibxpress.com and click on Health and Wellness. Healthy LifestylesSM Solutions Program  Personal Health Profile - Health risk assessments Enroll in Weight Watchers®, Weight Watchers® Online, or an members complete through the member portal that results approved weight management program at any network in a health analysis and personalized action plan. hospital.  Educational Videos - View short educational videos on any SM The Healthy Lifestyles Solutions Weight Management one of thousands of health topics. Program will reimburse you up to $150 for the cost of an approved weight management program. To get started:  Connections Health Management Programs - Provides members with an accurate, confidential and personalized  Sign up for an approved weight management program action plan to support physicians’ relationship with their  Attend the approved program patients and enhance their ability to provide evidence-based care.  Submit documentation and request your reimbursement  Nutrition Counseling - Members receive up to six visits a Log onto www.ibx.com/reimbursements and request your year—at no deductible—with a registered dietician to learn reimbursement by submitting proof of participation and how to eat a healthier diet. payment. Once all of your documentation is submitted, you can request your reimbursement to be paid by direct deposit  And much more or American Express rewards gift card. Tobacco Cessation Program Fitness Program Reimbursement No matter who you are, you can find a program that will give you You can get up to $150 back when you join a full-service the type of support and encouragement you need to kick the fitness center. Exercise regularly (120 times a year) at an habit. Receive up to $150 back when you complete your choice approved fitness center, record your workouts, and submit of proven tobacco cessation programs. Eligible programs your documentation for reimbursement. Reimbursements can include those that focus on behavior modification and provide be obtained by direct deposit or an American Express rewards frequent and regular support such as weekly meetings or gift card. telephone-based sessions. Other IBC Health & Wellness Resources You can work with your health care provider to determine which method is best for you. You may meet one-on-one with a IBC offers access to a variety of products and services to help provider, or choose a program that offers group support. Some you live a healthy lifestyle and manage your everyday life. You programs can even help you manage stress, avoid weight and your family members can obtain information on the gain, and overcome barriers to quitting. You can also choose a following programs: program offered by a network hospital in your area. Search for  IBC Health Coaches - IBC’s Health Coaches are registered a network hospital in your area at www.ibxpress.com or nurses available 24 hours a day, 7 days a week to help you contact our Health Resource Center at 1-800-ASK-BLUE for with your health needs and questions, whether it be for a more information. chronic condition or for assistance coordinating visits with doctors or specialists. Your PCOM dedicated health coaches As an IBC member, you are are Erin Cook (1-215-241-3062) and Nichole Getz (1-215- automatically eligible for Blue365. 365 241-4293). days a year, Blue365 is available to help  Stress Management - Receive a stress-relief bulletin. you make important decisions about your health and wellness. Simply log on to Blue365 from the ibxpress.com  Baby BluePrints - A maternity program designed to help you website and you will receive access to discounts, nutrition be healthy, confident, and comfortable throughout your and weight management programs, laser vision correction, pregnancy. parent and senior care, health travel and more.  24/7 Nurse Line - Members have access to speak with a registered nurse 24 hours a day, 7 days a week. Visit your member website at www.ibxpress.com to:  Achieve Well-Being - Personalized online tools and  Find a provider resources that help you achieve what’s important to you in  View claims a way that’s simple, easy, and fun.  Review your coverage details  View health & wellness programs 17 PCOM EMPLOYEE PROCEDURE FOR BLOODBORNE PATHOGEN INJURY

NEEDLE STICK/SPLASH

HOSPITAL SETTING Employee (i.e. Intern or Residents) is to follow the policy of that institution by:

1-going to the E.R. for immediate care (i.e. wound care PEP,labs) OR 2-going to Emp.Health Dept. /OHS of the institution for immediate care during normal work hours.

OFFICE SETTING At the time of a BLOODBORNE Pathogen injury, employee should be given Immediate care, i.e. wound care, PEP, lab testing for him/herself.The”source” patient will have lab testing done in accordance with that State’s laws.

(Lab testing for PCOM employee’s and “source” patient will include but NOT be limited to HIV, Hepatitis BS Ab, Hepatitis C Ab and any other labs deemed appropriated should PEP [Post Exposure Prophylaxis] be recommended).

In all cases, Student Wellness should be notified of the injury<72 hrs.at (215)871-6420. In all cases a copy of incident report and lab work should be faxed to 215-871-6309

BILLING/GUARANTOR INFORMATION All fees related to the injury will be the responsibility of PCOM PCOM/Risk Management 4190 City Avenue Philadelphia, Pa 19131 215-871-6609

______Sr.Vice President of Academic Affairs/Dean Director of Risk Management and Insurance The Philadelphia College of Osteopathic Medicine

Safety Manual

Occupational and Environmental Safety Department 4190 City Avenue Philadelphia, PA 19131 (215) 871-6360 [email protected] PCOM Safety Manual

Contents

Part 1 Introduction and Emergency Contacts Part 2 Worker’s Compensation Part 3a Plant Operations – Georgia Part 3b Plant Operations – Philadelphia Part 4 Student/Resident Medical Records Part 5 Security / Public Safety Part 6 Radiation Safety Part 7 Laser Safety Part 8 Health/Safety Issues for the Basic Sciences Appendix A: BSL-2 Guidelines Appendix B: BSL-2 Safety Checklist Part 9a Biomedical Waste Operating Plan – Georgia Part 10 Automated External Defibrillator (AED) Program Part 11 Exposure Control Plan Appendix A: Respirator Maintenance Part 12 Hazard Communication Program Part 13a Chemical Hygiene Plan – Georgia Part 13b Chemical Hygiene Plan – Philadelphia Part 13c Chemical Inventory Guidance Part 14 Formaldehyde Guidelines Appendix A: Health Effects and Risks Part 15 Mercury Spills Part 16 LAR Emergency Plan (Summary) Part 17a DOT Security Plan – Georgia Part 18 Confined Spaces Safety Program Part 19 Lockout/Tagout Program

Updated May 2017 Part 1. Introduction and Emergency Contacts

1. Principle of Safety. Philadelphia College of Osteopathic Medicine (PCOM) is committed to programs of accident and injury prevention and to compliance with relevant environmental, health, and safety laws and regulations. However, this commitment cannot be maintained without the cooperation and sense of responsibility of each employee (administrator, faculty, staff, intern, and resident) and student. Each person's area of work and expertise should not be considered an isolated microcosm distinct from the general, day-to-day functioning of PCOM at large. A safe and healthy Campus environment builds on the pillars of safe and healthy office, lecture room, and laboratory environments. In addition, committees perform vital functions linking both the local work environment with the Campuses at large, and the whole PCOM community with federal, state, local, and institutional programs. These committees (IACUC, IEHS, IRB, and Research) collectively provide information to the PCOM community about health and safety hazards, update and execute governmental rules and regulations, identify and correct potential and actual health and safety hazards, monitor the effectiveness of existing programs, and approve research proposals.

2. Application of Program Guidance. Philadelphia College of Osteopathic Medicine (PCOM) is committed to upholding high ethical standards and promoting compliance with applicable laws, rules and regulations in the conduct of all of its activities, whether performed in its role as Pennsylvania non-profit corporation, academic institution, employer, business entity or provider of health care services. The PCOM Occupational Health and Safety Program applies to PCOM Trustees, officers, Faculty, students and employees, including PCOM-affiliated physicians, physicians-in-training, physician assistants, nurses and other individuals involved in the provision of health care services (herein, Health Care Professionals), (collectively, the PCOM Community). This manual will be reviewed annually and updated if necessary.

1-1 Updated April 2017 Emergency Contacts – Philadelphia Campus:

PCOM Security Command Center 215-871-6351 or 6911 from on-campus telephones Director, Security and Public Safety 678-225-7517 Security Lieutenant 215-871-6326 Fire reporting 215-871-6351 or 6911 from on-campus telephones Spill reporting 215-871-6351 or 6911 from on-campus telephones

Crime reporting 215-871-6351 or 6911 from on-campus telephones Chief Occupational/Environmental Safety Officer 215-871-6360 or 215-871-6341 off- hours Environmental Health and Safety Specialist 678-225-7712

Chemical hood alarm reporting 215-871-6950

Emergency Contacts – PCOM Georgia:

PCOM Security Dispatcher 678-225-7451 or 2911 from on-campus telephones Director - Security and Public Safety 678-225-7517 Fire reporting 678-225-7451 or 2911 from on-campus telephones Crime reporting 678-225-7451 or 2911 from on-campus telephones

SECURITY EMERGENCY X3911 PCOM Security Desk X3290 Maintenance X7458 Plant Operations X2355 Police & Fire X9911

Emergency Contacts – PCOM South Georgia

SECURITY EMERGENCY 229-668-3290 or 3911 from on-campus telephone Fire Reporting 229-668-3290 or 3911 from on-campus telephone Crime Reporting 229-668-3290 or 3911 from on-campus telephone PCOM Security Desk X3290 Maintenance X6151 Plant Operations X6151 Police & Fire X9911

Rev. 10/2019

1-2 Violations reporting:

PCOM employees shall report safety violations and complaints to the employee’s supervisor, the Chief Environmental/Occupational Safety Officer and the Chief Compliance Officer.

PCOM students shall report safety violations and complaints to the Chair of the department, the Chief Environmental/Occupational Safety Officer and the Chief Compliance Officer.

PCOM employees and students shall report regulatory violations to the Chief Compliance Officer.

Violations and Complaints Anonymous Telephone Hotline: (877) 874-8416

1-3 Updated April 2017 Part 2. Worker’s Compensation

Title: WORKERS’ COMPENSATION Policy: 4.99

Policy: In compliance with state law, Philadelphia College of Osteopathic Medicine has established a Worker’s Compensation Program for employees who are injured in the course of performing their assigned job responsibilities. It is PCOM’s responsibility to provide and monitor complete medical treatment of the injury until the employee can return to work. The responsibility of PCOM includes, but is not limited to, initial emergency treatment, subsequent treatment by pre-established panel physicians, mandatory follow-up treatment as requested by the attending panel physicians or the Workers’ Compensation insurance carrier, development and assignment of a medically approved position, if available, and/or provisions for retraining. Job-related injuries and occupational illnesses are handled in accordance with the Pennsylvania Workers’ Compensation Act, 77 P.S. 1 et seq, as amended and the Pennsylvania Workers’ Compensation and Occupational Disease Act and the laws of the state of Georgia. The Risk Management Department is responsible for administering the program in both Pennsylvania and Georgia.

Purpose: To set forth the policy on Workers’ Compensation for all PCOM Employees.

Scope: Applies to all employees at PCOM, interns and residents.

Procedure:

1.0 Medical Treatment

1.1 If an employee is injured on the job, medical attention will be provided at once. The employee will immediately report any injury to his/her supervisor. In Philadelphia, the employee will be sent to WORKNET Occupational Medicine, 5800 Ridge Avenue, Suite 234, Philadelphia, PA 19128, for medical attention or the nearest hospital emergency room. The hours for WORKNET are 8:00a.m. to 4:30 p.m. Monday through Friday. In Georgia, the employee will be seen by a physician listed on the workers’ compensation carrier’s approved listing or the nearest hospital emergency room if required.

Updated April 2017 1.2 It is the responsibility of the employee to notify their supervisor who will complete an Employee Incident Report (available on Nucleus). The supervisor will submit a detailed written account of the injury. The report will include the date and time of the injury, what the employee was doing at the time, how the injury occurred and a statement from witnesses to the incident.

1.3 In all cases the supervisor or department head will notify the Risk Management Department within 24 hours of any employee injury, whether or not medical treatment was required. The Employee Incident Report from must also be provided to the Risk Management Department.

1.4 Every injured employee in Pennsylvania must sign and date the Workers’ Compensation Employee Notification and Medical Records Release Authorization forms following an injury and submit them to the Risk Management Department. Copies of these forms are attached to this policy or may be obtained from the Risk Management Department.

1.5 If the employee is admitted to a hospital, it will be to the service of a Panel Physician if possible. The attending physician in the Emergency Room must notify the Risk Management Department of the admittance as soon as possible.

1.6 In Philadelphia, WORKNET will examine, diagnose and treat the patient or refer them to an appropriate Panel Physician. WORKNET will also monitor, manage and coordinate the progress of the employee throughout the recovery process. This responsibility will include, but not be limited to periodic contact with the employee, panel physicians and the Risk Management Department.

A. The panel will include specialists in Orthopedics, Neurology, Surgery, Internal Medicine, Rehabilitation Medicine, Ophthalmology, Physical Therapy and Osteopathic Practices and Principles.

B. A list of current Panel Physicians appears at the end of this policy and is available on Nucleus, the Human Resources Department, the Risk Management Department and at various locations throughout the campus.

2-2 Updated April 2017 C. All new employees are given a list of Panel Physicians to be used in case of an on the job injury.

D. The Panel Physicians will provide medical treatment to an employee with a work related injury for the first ninety days (90) after being treated in either WORKNET or the Emergency Room. When an employee is treated by a Panel Physician during the first ninety days (90), all medical bills will be paid by the workers’ compensation carrier. After nine days (90), the employee can elect to be treated by his/her own personal physician, but must notify WORKNET and Risk Management within five (5) days of the first visit to personal physician.

E. A Panel Physician will see the employee within three days (3) when referred WORKNET.

F. The Panel Physician will submit a status report to WORKNET after each visit made by the employee within five (5) working days.

1.7 In Georgia, the approved insurance carrier physician will monitor, manage and coordinate the progress of the employee throughout the recovery process.

A. The insurance carrier will have a listing of participating specialists that will include Orthopedic, Neurology, Surgery, Internal Medicine, Rehabilitation Medicine, Ophthalmology, Physical Therapy and Osteopathic Practices and Principles.

B. A listing of current specialists may be found on the carrier’s website (www.mywcinfo.com) in the GA PCOM Administrative Offices or by contacting the Risk Management Department at 215-871-6609.

C. The approved Panel Physician will coordinate, manage and monitor the employee’s care throughout the duration of the treatment.

2.0 Reporting of Incident

2-3 Updated April 2017 The Risk Management Department will report each accident/injury to the Workers’ Compensation Insurance Company and/or third party administrator. The Risk Management Department will act as the liaison with the Workers’ Compensation Insurance Company and legal activities when necessary.

3.0 Employee Compensation

Compensation will be made to the injured employee according to the following schedule:

A. If an employee is sent home after incurring a work related injury the employee will receive wages for hours worked and earned time (sick time, personal days, vacation days etc.) for hours not worked that shift.

B. There is a 7-day waiting period in Pennsylvania and Georgia; therefore, a disability must exist for 7 days before wage loss compensation begins. If an employee is absent less than 8 days, sick time will be used in accordance with the sick time policy. If absent more than 7 days but less than 14 days, the first 7 days are paid through sick days and the 8th through the 13th will be paid by the insurance carrier. If an employee is absent more than 13 days, the insurance carrier will pay that employee from the first day of absence due to the work related injury. The employee in turn will be credited for any sick time that was used for the first 7 days. If the employee receives both sick time payment and Workers’ Compensation, the Payroll Department will deduct the sick time payments from the first pay check when the employee returns to work.

C. Employees will receive workers’ compensation wages according to the rate schedule set by PA and GA State Law.

4.0 Leave of Absence

A. After seven (7) consecutive days of absence, the employee must file for Medical Leave of Absence in accordance with the Human Resources’ Leave of Absence Policy. Leave of Absence requests must be handled by the department supervisor and Human Resources.

2-4 Updated April 2017 B. Employees injured on the job will maintain paid medical benefits from PCOM for a maximum of 6 months. All accrual vacation, sick and personal days are discontinued when an employee is placed on a leave of absence. After the 6 month period, the employee may remain on the Group Health Plan under the COBRA provisions. Employees will be notified by the Human Resources Department prior to the 6 month deadline.

5.0 Return to Work

All employees who have been injured on the job must receive clearance from the appropriate Panel Physician or their treating physician prior to returning to work.

2-5 Updated April 2017 2-6 PMA Management Corp. Updated April 2017 WORKERS’ COMPENSATION EMPLOYEE NOTIFICATION

Workers’ Compensation is designed to provide wage loss benefits and reimbursement for reasonable medical care for one who is injured on the job. Your employer shall provide payment for reasonable surgical and medical services, services rendered by physicians or other health care providers, medicines and supplies, as and when needed. Your employer, in compliance with the Workers’ Compensation Act, has posted a list of at least six (6) medical providers from which you are to select. You are to obtain treatment from one of the providers of your choice for ninety (90) days from the date of your first visit. If you are faced with an immediate medical emergency, you may secure assistance from the closest hospital, physician or other health care provider of your choice. If follow up treatment is needed, you must then seek treatment from a physician or other health care provider listed on your employer’s physician panel list for the first ninety (90) days from the date of your first treatment. If during the initial 90-day period you wish to change medical providers, you must once again re-visit your employer’s panel and select a new physician. If you do not seek treatment from a provider on the panel list for the initial 90 days following your first visit, your employer will not have to pay for the services rendered. If one of the listed providers recommends invasive surgery, you are entitled to a second opinion from a physician of your choice. Should your physician’s opinion differ, and you choose that opinion, the panel physician will abide by same for 90 days. After the initial 90-day period, if additional or continued treatment is needed, you may now choose to go to another physician or health care provider of your choice. Should you decide to change providers, you must notify your employer within five (5) days of your first visit with your new provider. Failure to notify your employer will relieve your employer of the responsibility for the payment of the services rendered if such services are determined to have been unreasonable or unnecessary. Any person who knowingly and with intent to defraud any insurance company or other person files an application for insurance or statement of claim containing any materially false information or conceals for the purpose of misleading, information concerning any fact material thereto commits a fraudulent insurance act, which is a crime and subjects such person to criminal and civil penalties. I hereby acknowledge that I have been informed of and understand my rights and duties under the Workers’ Compensation Act.

Employee signature Date

PMA Management Corp.

Page 2

WORKER’S COMPENSATION EMPLOYEE NOTIFICATION

Workers’ Compensation Information

(1) The workers' compensation law provides wage loss and medical benefits to employees who cannot work, or who need medical care, because of a work- related injury. (2) Benefits are required to be paid by your employer when self-insured, or through insurance provided by your employer. Your employer is required to post the name of the company responsible for paying workers' compensation benefits at its primary place of business and at its sites of employment in a prominent and easily accessible place, including, without limitation, areas used for the treatment of injured employees or for the administration of first aid. (3) You should report immediately any injury or work-related illness to your employer. (4) Your benefits could be delayed or denied if you do not notify your employer immediately. (5) If your claim is denied by your employer, you have the right to request a hearing before a workers' compensation judge. (6) The Bureau of Workers' Compensation cannot provide legal advice. However, you may contact the Bureau of Workers' Compensation for additional general information at: Bureau of Workers' Compensation, 1171 South Cameron Street, Room 103, Harrisburg, Pennsylvania 17104-2501; telephone number within Pennsylvania (800) 482-2383; telephone number outside of this Commonwealth (717) 772-4447; TTY (800) 362-4228 (for hearing and speech impaired only); www.state.pa.us, PA Keyword: workers comp.

PMA Management Corp. Updated April 2017

Temporary Prescription Services

Attention Injured Worker • On your first visit, please give this notice to any pharmacy listed below to expedite the processing of your approved workers’ compensation prescriptions. (Based on the established parameters by your employer.) • Questions or need assistance locating a participating pharmacy: Call the Express Scripts Contact Center at 800-897-9470.

Atencion Trabajador Lesionado: • Este formulario de identificación para servicios temporales de prescripción de recetas por compensación del trabajador DEBERÁ SER PRESENTADO a su farmacéutico al surtir su(s) receta(s) inicial(es). • Si tiene cualquier duda o necesita localizar una farmacia participante, por favor contacte al área de Atención a Clientes de Express Scripts, en el teléfono 800-897-9470.

Attention Supervisor: Please complete the following information for the injured worker.

Express Scripts Employee Information ID #: SSN to be presented to the pharmacy at the time prescription is filled First M Last Date of Injury: / / Mailing Address MM/DD/CCYY

Group #: KVQA Street Address or PO Box City State Zip Employee Date of Birth: / / Employer Name MM/DD/CCYY

Attention Pharmacist • Express Scripts administers this workers’ compensation prescription program. Follow the steps below to submit a claim. • For assistance, call the Express Scripts Contact Center at 888-786-9640. Pharmacy Processing Steps Step 1 Enter bin number 003858 Step 2 Enter processor control A4 Step 3 Enter the group number as it appears above (KVQA) Step 4 Enter the injured worker’s 9 digit ID# Step 5 Enter first name & last name Step 6 Enter the injured worker’s date of injury (enter in PA field in the format ccyymmdd)

Participating Pharmacy Chains A & P Coborn's Food City Major Value Randalls Target Acme Pharmacy Costco Food Lion Marsh Drugs Rite Aid Texas Oncology Srvs Albertson’s Cub Fred's Medic Discount Rosauers The Pharm Albertson’s/Acme CVS Gemmel Medicap Rx Express Thrifty White Albertson’s/Osco D&W Giant Medistat RXD Times Albertson’s/Sav-On Dahl's Giant Eagle Meijer Safeway Tom Thumb Amerisource Bergen Dierbergs Giant Foods Minyard Sam’s Club Tops Anchor Pharmacies Discount Drugmart Hannaford NCS HealthCare Sav-On Ukrop's Arrow Doc's Drugs Harris Teeter Neighborcare Save Mart United Drugs Aurora Dominicks H-E-B Network PharmaceuticalsSchnucks United Supermarkets Bartell Drugs Drug Emporium Hi-School Pharmacy Northeast Pharmacy ServicesScolari's Vons Bigg's Drug Fair Hy-Vee Osco Sedano Waldbaums Bi-Lo Drug Town Jewel/Osco P & C Food Markets Shaw's Walgreens’ Bi-Mart Drug World Kash n Karry Pamida Shop 'N Save Wal-Mart BJ’s Wholesale Club Eckerd Keltsch Park Nicollet Shopko Wegmans Brooks Econofoods Kerr Pathmark ShopRite Weis Brookshire Brothers EPIC Pharmacy Kmart Pavilions Snyder Winn Dixie Brookshire Grocery Network Knight Drugs Price Chopper Stop & Shop Bruno FamilyMeds Kroger Publix Sun Mart Carrs Farm Fresh LeaderNet (PSAO) Quality Markets Super Fresh Cash Wise Farmer Jack Longs Drug Store Raley's Super Rx NOTE: This form is not valid in the state of Ohio. For all other states, liability of a workers’ compensation claim is not assumed based on the dispensing of medication(s) to a patient. © 2011 Express Scripts, Inc. All Rights Reserved

NOTICE TO EMPLOYEES

Your employer has provided for the payment of benefits under the Workers’ Compensation Act of this State

IN CASE OF WORK-RELATED INJURY

• If you suffer a work-related injury, your employer or its insurance company must pay for reasonable surgical and medical services and supplies, orthopedic appliances and prostheses, including training in their use. • In order to ensure that your medical treatment will be paid for by your employer or the insurance company, you must immediately advise your supervisor of your injury and be treated by one of the licensed physicians or practitioners of the healing arts listed below:

DESIGNATED PHYSICIANS (Including address, telephone number, and area of medical specialty)

CLINICS WORKNET Occupational Medicine 5800 Ridge Avenue, Suite 234 Philadelphia, PA 19128 215-487-4540 (Hours: 8:00a.m. - 4:30p.m. (M-F) PHYSCIANS/SPECIALISTS

Mandarino, Michael J., MD Philadelphia Orthopedic Group OMM Department Orthopedic Surgery Orthopedic Surgery 4190 City Avenue, Suite 330 2832 Belmont Avenue 2 Bala Plaza, Suite IL-1 Philadelphia, PA 19131 Philadelphia, PA 19131 Bala Cynwyd, PA 19004 215-871-6425 215-878-1212 610-667-7712

Guagliardo, Joseph P., DO Lubeck, Joseph S., DO Parenti, Daniel J., DO PCOM-Surgery Neurology PCOM Intermed Associates Orthopedics 2 Bala Plaza, Suite IL-9 Internal Medicine 4190 City Avenue, Suite 509-R Bala Cynwyd, PA 19004 4190 City Avenue, Suite 330 Philadelphia, PA 19131 610-667-0278 Philadelphia, PA 19131 215-871-6942 215-871-6337

Russin, Simon R., DO Browngoehl, Laurie, MD Lesher, Amy RPT Ophthalmology Physical Medicine & Therapy Body Rebuilders 301 E. City Avenue, Suite 335 551 W. Lancaster Avenue Physical Therapy Bala, Cynwyd, PA 19004 Haverford, PA 19041 225 City Avenue, Suite 250 610-617-4164 610-527-8808 Bala Cynwyd, PA 19004 610-668-4055

OFFICIAL NOTICE

This business operates under the Georgia Workers' Compensation Law.

WORKERS MUST REPORT ALL ACCIDENTS IMMEDIATELYTO THE EMPLOYER BY ADVISING THE EMPLOYER PERSONALLY, AN AGENT, REPRESENTATIVE, BOSS, SUPERVISOR, OR FOREMAN. If a worker is injured at work, the employer shall pay medical and rehabilitation expenses within the limits of the law. In some cases the employer will also pay a part of the worker's lost wages. Work injuries and occupational diseases should be reported in writing whenever possible. The worker may lose the right to receive compensation if an accident is not reported within 30 days. The employer will supply free of charge, upon request, a form for reporting accidents and will also furnish, free of charge, information about workers' compensation. The employer will also furnish to the employee, upon request, copies of board forms on file with the employer pertaining to an employee's claim. A worker injured on the job must select a doctor from the list below. The minimum panel shall consist of at least four physicians, including an orthopedic surgeon with no more than two physicians from industrial clinics. Further, this panel shall include one minority physician, whenever feasible. (See Rule 201 for definition of minority physician). Effective January 1, 2002, the minimum panel shall consist of at least six physicians in addition to the requirements set forth above. The Board may grant exceptions to the required size of the panel where it is demonstrated that more than four physicians or groups of physicians are not reasonably accessible. One change of doctor, from the list, may be made without permission. Further changes require the permission of the employer or the State Board of Workers' Compensation. State Board of Workers' Compensation 270 Peachtree Street, N.W. Atlanta, Georgia 30303-1299 404-656-3818 or 1-800-533-0682 Http://www.ganet.orga/sbwc Choice Care Gwinnett Urgent Care, PC 6760 Jimmy Carter Blvd. 1300 Peachtree Industrial Blvd, # 4101 Norcross, GA 30071 Suwanee, Ga 30024 678-892-2000 770-831-5525 Dominion Orthopaedic Clinic Peachtree Orthopaedics 4235 Johns Creek Pkwy., Suite B 3870 Pleasant Hill Rd, Ste 100 Suwanee, GA 30024 Duluth, GA 30092 770-455-4009 404-355-0743 Resurgens Orthopaedics Thomas Eye Group 758 Old Norcross Rd Ste 100 1120 Peachtree Industrial Blvd Suite 101 Lawrenceville, GA 30046 Suwanee, GA 30024 770-962-4300 770-809-3366

Updated April 2017

EMPLOYEE INFORMATION – PLEASE TYPE OR PRINT (TO BE COMPLETED BY EMPLOYEE) NAME (LAST, FIRST, MIDDLE INITIAL)

EMPSOCIALL SEOCUYREITEY INCIDENT REPOMRTARITAL S TATUS BIRTH DATE HOME PHONE # OF DEPENDENTS UNDER 18

REGULAR WORK SCHEDULE TIME JOB TITLE DATE OF HIRE

CURRENT A DDRESS (STREET, CITY, STATE)

INCIDENT INFORMATION ADDRESS O F INCIDENT (STREET, CITY, STATE) DATE OF INCIDENT TIME OF INCIDENT

DESCRIBE H OW THE INCIDENT OCCURRED AND ANY RESULTING INJURY

LIST ANY EQ UIPMENT, MACHINERY, OR CONTRIBUTING FACTORS TO THE INCIDENT (PLEASE ONLY INCLUDE FACTUAL INFORMATION)

IDENTIFY PARTS OF BODY INJURED:

LIST OTHER EMPLOYEES INVOLVED OR WITNESSES

I AGREE THAT THE ABOVE IS TRUE, CORRECT, AND COMPLETE

EMPLOYEE’S SIGNATURE DATE TELEPHONE # SUPERVISOR’S REPORT SUPERVISOR S NAME DATE INCIDENT REPORTED DEPARTMENT

DID YOU WITNESS THE INCIDENT? NO YES DESCRIBE/COMMENTS: WHAT WAS THE EMPLOYEE DOING WHEN INJURED? (BE SPECIFIC, IDENTIFY TOOLS OR MATERIALS INVOLVED AND EXPLAIN HOW THEY WERE BEING USED)

HOW DID THE INJURY OCCUR? (DESCRIBE FULLY THE EVENTS RESULTING IN THE INJURY/ILLNESS. NAME ANY OBJECTS OR SUBSTANCES INVOLVED)

DID THE INJURY RESULT FROM MECHANICAL DEFECT? NO YES DESCRIBE/COMMENTS: DID THE INJ URY RESULT FROM AN UNSAFE ACT? NO YES DESCRIBE/COMMENTS:

WAS ACTIO N TAKEN TO PREVENT SIMILAR INCIDENTS? NO YES DESCRIBE/COMMENTS:

EMPLOYEE WAS REFERRED TO: EMERGENCY ROOM REFUSED TREATMENT

SUPERVISOR’S SIGNATURE DATE PHONE

MEDICAL INFORMATION EXAMINING PHYSICIAN: DATE

DIAGNOSIS:

Part 3a. Plant Operations - Georgia

The Plant Operations Department on PCOM’s Georgia campus consists of the following departments:

• Maintenance • Environmental Services • Security and Public Safety • Parking Services

The Security and Public Safety Departmental issues are addressed in Section 5 of the Safety Manual.

A. MAINTENANCE:

OBJECTIVE: The responsibilities of the Maintenance Department are to keep everything working properly including but not limited to: equipment, air conditioning, heating, etc. Preventative maintenance is performed throughout the entire facility. Emergency situations are addressed immediately.

Should any type of maintenance work need to be done, the requesting department must submit a School Dude Work Order. Should there be an immediate need for service, still submit a School Dude Work Order and then call the department at extension 7458.

If there is no answer on the departmental telephone, call the Associate Director, 215- 805-9050, who will then address your problem.

B. ENVIRONMENTAL SERVICES

OBJECTIVE: To maintain a clean and environmentally safe environment for all PCOM employees, students, physicians and visitors.

Should any environmental services be needed, call the departmental telephone extension of 7458. If there is no answer, leave a message. The messages are checked hourly.

Should there be an immediate need for service and no one is answering the departmental telephone, call the Associate Director, 215-805-9050, who will then address your problem. Performs special set ups for special occasions. These requests must be given to the Department, in writing, either by e-mail addressed to John Khan or by memo, at least one week prior to the set up. No requests will be taken verbally.

3a-1 Updated April 2017 C. PARKING SERVICES

OBJECTIVE: To maintain all parking areas, making certain the areas are clean and safe for all PCOM employees, students, physicians and visitors.

Should there be any problems with the parking equipment or parking in any areas, contact the Security Desk, extension 7451, who will relay the information to the appropriate personnel.

3a-2 Updated April 2017

Part 3b. Plant Operations - Philadelphia

The Plant Operations Department on PCOM’s Philadelphia campus consists of the following departments:

• Maintenance • Environmental Services • Security and Public Safety • Parking Services • Student Activity Center.

The Security and Public Safety Departmental issues are addressed in Part 5 of the Safety Manual.

A. MAINTENANCE:

Should any type of maintenance work need to be done, the requesting department must submit a School Dude Work Order. Should there be an immediate need for service, still submit an MP2 Work Order and then call the department at extension 6750.

If there is no answer on the departmental telephone, call the duty engineer on pager 5676, who will then address your problem.

B. ENVIRONMENTAL SERVICES

OBJECTIVE: To maintain a clean and environmentally safe environment for all PCOM employees, students, physicians and visitors.

Should any environmental services be needed, call the departmental telephone extension of 6750. If there is no answer, leave a message. The messages are checked hourly.

Should there be an immediate need for service and no one is answering the departmental telephone, call the Command Center at extension 6351, who will relay the information to the appropriate personnel. Should there be any hazardous/chemical spills, contact Security immediately at extension 6351. DO NOT HANDLE SPILLS YOURSELF. Environmental Services does not handle hazardous/chemical/infectious waste disposal.

3b-1 Updated April 2017

Environmental Services performs special set ups for special occasions. These requests must be given to the Department, in writing, either by e-mail addressed to Harriette Fine or by memo, at least one week prior to the set up. No requests will be taken verbally.

C. PARKING SERVICES

OBJECTIVE: To maintain all parking areas, making certain the areas are clean and safe for all PCOM employees, students, physicians and visitors.

Should there be any problems with the parking equipment or parking in any areas, contact the Command Center at extension 6351, who will relay the information to the appropriate personnel.

The Bursar's Office is responsible for parking registration. You must provide the make and model of the vehicle as well as the required deposit. These guidelines are in the Bursar's Office, Suite 203 in Rowland Hall.

3b-2 Updated April 2017 Part 4. Office of Student/Resident Medical Records

UNIVERSAL PRECAUTIONS / STANDARD PRECAUTIONS

See Part 11 (Exposure Control Plan) of the Safety Manual. .

RESPONSIBILITIES: The PCOM Office of Student/Resident Medical Records (OSRMR) will review policies and procedures relating to protection and prevention, including Standard Precautions, immunizations, engineering/work practice controls and personal protective equipment (PPE) at least every other year and revise as necessary. Department Heads are responsible for seeing that their employees have knowledge of and access to engineering, work practice controls and practice standards to eliminate or minimize employee exposure to blood and other potentially infectious materials. Department managers are responsible for implementing this plan in their areas. They are responsible for identifying new positions or tasks and procedures which involve occupational exposure and then adding these to their departmental lists.

TRAINING AND EDUCATION OF EMPLOYEES: All employees and students with occupational exposure to blood or OPIM receive training at orientation and at least annually thereafter via department heads or contact OSRMR for individual appointments.

PERSONNEL TUBERCULOSIS POLICY POLICY: All PCOM personnel will be screened for tuberculosis (TB) at the time of their Pre- Employment Physicals. HCWs with direct patient contact will be screened every six months (hospital-based) while office/clinic staffs are screened yearly. Frequency will be determined in conjunction with schedule for the most frequented affiliated sites.

SCOPE: This policy applies to ALL employees with patient contact and Medical staff from this point forward "employees" meaning HCWs.

POLICY INFORMATION: It is preferred that personnel be screened by the OSRMR. If personnel are screened by their personal physician, documentation of screening procedures and results must be provided to OSRMR for evaluation. Any employee with confirmed or suspected TB disease shall not return to work until TB is excluded or the person is on therapy and declared non-infectious.

4-1 Updated April 2017

Mantoux is the only method of testing approved by OSHA. OSRMR will set up an office visit so a medical evaluation for any employee/student with a positive PPD tests and/or conversion and will document the evaluation results in personnel medical files. An individual with a positive PPD test result need not be restricted from work unless he/she has signs and symptoms of active TB.

RESPONSIBILITIES: SWC is responsible for setting up evaluation of available particulate respirators (PRs) and outlining use guidelines. Department Heads are responsible for contacting OSRMR to set up all appointments. For assuring that employees have been qualitatively fit tested at the time of their Pre- Employment physical, any time a "new" type of respirator is introduced, or any dramatic weight loss/gain occurs. Each employee is responsible for wearing the appropriate PR for their area or task. Department Heads, for Interns and Residents, are responsible for assuring that their personnel comply with TB surveillance. OSRMR or PCOM pre-employment doctor is responsible for administering purified protein derivative (PPD) tests to HCWs at the time of employment annually at 6 month intervals, exposures and maintaining all records related to same. OSRMR will provide the Personal Respiratory Protection Equipment (PRPE) at the time of employment, conduct the Fit Test initially and each time the product changes, as required by OSHA. (All department heads/office managers will set up appointments with OSRMR for all new hires.) Annual training and education will be conducted by the department head/office manager. Assessment of risk of transmission of TB in PCOM's Health Care Centers (HCCs) will be determined by the Director of each Health Care Facility. All annual and semiannual PPD screening results will be documented in medical records.

4-2 Updated April 2017

PREGNANT WOMAN GUIDELINES

POLICY: Guidelines have been developed for the protection of PCOM employees who are or may be pregnant. Due to the nature of the education program at PCOM (rotation of our Interns, Residents and Medical Students), rotating PCOM employees/students are encouraged to familiarize themselves with the variations in these standards located in the Infection Control manuals of each hospital to which they rotate.

SCOPE: The policy applies to all PCOM Employees and Medical Students

POLICY INFORMATION: All personnel, especially female personnel who are or may be pregnant, should know their immune status with regard to the following diseases: • Rubella (German measles) • Varicella/Herpes Zoster (Chickenpox) • Rubeola (Measles) • Hepatitis B

Pregnancy itself does not constitute an increased risk for acquiring infectious diseases. It is usually not necessary to restrict pregnant personnel from caring for a patient with an infection or participating in research. Restriction from patient contact is based on history of immunity and not on pregnancy.

4-3 Updated April 2017

Location of PCOM Philadelphia Health Care Centers

1. Family Medicine at PCOM 4190 City Avenue/Medical Office Building Suite 100 Philadelphia, PA 19131 Phone: 215-871-6380 Fax: 215-871-6381

2. Family Medicine at PCOM 4190 City Avenue/Medical Office Building Suite 533 Philadelphia, PA 19131 Phone: 215-483-6380 Fax: 215-483-4414

3. PCOM's Cambria Healthcare Center 2100 W. Cambria Street Philadelphia, PA 19132 Phone: 215-578-3300 Fax: 215-578-3335

4. PCOM's Lancaster Avenue Healthcare Center 4148 Lancaster Avenue Philadelphia, PA 19104 Phone: 215-662-0119 Fax: 215-662-5339

4-4 Updated April 2017

Part 5. Security / Public Safety

Objectives: • To maintain a uniform standard of professionalism in the protection of the Philadelphia College of Osteopathic Medicine environment, inclusive of faculty, staff, students, visitors and their property. • To maintain a clean and environmentally safe environment for all employees, faculty, staff students and visitors.

Security-Organization and Duties: The Department of Security and Public Safety is located in the Rowland Hall Medical Office Building, Suite #232. The Director of Security and Public Safety is responsible for departmental administration.

Security Operations: PCOM security personnel maintain order on campus by educating the campus community on security concerns and by enforcing College procedures. PCOM security personnel do not have arrest powers, but consult with police authorities to gather information on criminal activity on campus and assess potential risks which may exist on or near the campus. Perpetrators are reported accordingly. All students and employees are issued an identification badge which they are encouraged to wear at all times. Visitors and out-patients are required to sign in at all times. On Saturdays and Sundays and at specific locations between the hours of 7:00 p.m. and 7:00 a.m., Mondays through Friday, students and employees are required to sign in. Entry to campus facilities, other than authorized visitor/guest areas is restricted unless clearance has been granted by individual administrators or by the Department of Security. Safety violations trigger an immediate request for corrective action.

Criminal activities and emergency situations are to be reported to the Security Department when they are observed. Criminal activities will be investigated and local law enforcement authorities will be notified as necessary. Alleged perpetrators will be apprehended and detained until the arrival of law enforcement personnel. Security personnel are not permitted to carry lethal or non-lethal weapons while on duty. Only appropriate government law officers are permitted to enter the campus armed.

5-1 Updated May 2017 Escort Service: At any time students and employees may call campus security and request escort service from any campus building to another building or the parking areas. Call security directly at extension 6351 and an officer will come to your location as soon as possible.

Crimes Can Be Reported to Police: In the event of a crime, students are strongly encouraged to contact PCOM security or, in extreme cases, to directly contact the Philadelphia Police. PCOM security department records all reported crimes that occur on campus. As required by the College and University Security Act of Pennsylvania, the College submits a crime report annually to the state police. In accord with Pennsylvania's College and University Information Act (Act 73) of 1988, PCOM submits an annual report of campus crime to the state police. In accordance with the federal Student Right to Know and Campus Security Act of 1990, PCOM will submit, upon request, a copy of this report to the Secretary of the U.S. Department of Education.

Training: The regulations of the Occupational Safety and Health Administration (OSHA) require that all employees are provided with appropriate training and information to assure that they are aware of potential hazards at the work place. An "Office Safety Check List" is provided on the next page. The Hazard Communication Program at PCOM attempts to provide appropriate response to the Hazard Communication Standards of OSHA. Training is offered at the employee orientation and when requested by any departments at PCOM.

5-2 Updated May 2017 Office Safety Checklist The following "checklist" items will contribute to a safe office environment: 1. Wear appropriate eye protection to avoid visual fatigue from extensive computer use.

2. Exercise hands and wrists periodically to avoid strain from extensive typing.

3. Avoid overreaching in order to prevent back strain. Stand up and stretch yourself.

4. Lift objects (boxes, etc.) properly to avoid back strain.

5. If using a portable space heater keep the area around it clear of any flammable objects.

6. When clearing jammed paper from electronic equipment (printers, photocopiers fax machines) be especially careful in preventing ' hand injury and burns.

7. Wires and cords from electronic equipment should be secured/taped to prevent falls.

8. Use of extension cords is discouraged, surge protectors (should have the U.L. Seal of Approval) should be used on all electronic equipment.

9. At the end of the day make sure that all empty coolers are turned off to prevent overheating and possible fire.

10. Make sure that any construction work is properly cordoned off to prevent injuries from falls or falling debris.

11. PROMPTLY REPORT ALL SPILLS OR OVERFLOWS TO SECURITY. SEE EMERGENCY PROCEDURES FOR PA AND GA CAMPUS.

5-3 Updated May 2017 EMERGENCY PROCEDURES – PA CAMPUS

This is your Emergency Procedures Manual. The document is a collaborative effort of the Security and Public Safety and Plant Operations.

In the event of a fire, accident, illness, or other emergency, the directions provided within will enable you to react appropriately and safety. All members of your staff should be familiar with these procedures. It is recommended that this information be posted in your work areas. Please note that in all emergency situations, the Security Department/Dispatcher must be notified.

This material has been prepared by the Philadelphia College of Osteopathic Medicine, Department of Security and Public Safety and The Philadelphia Fire Department.

Directory

Accident or Illness In the event of an accident or illness of an employee, student, or visitor in your area, we recommend that you: 1. Call PCOM Security Dispatcher at X6911 Give the dispatcher the following information: PCOM Security Emergency ...... X6911 PCOM Security Dispatcher ...... X6351 Plant Operations ...... X6750 Philadelphia Police & Fire ...... X9911

A. The College Address B. The Building and Suite number C. Any details available of the accident or illness 2. DO NOT try to move the injured or ill person. Simply try to make them comfortable until emergency help arrives.

Elevator Emergencies If you are a passenger in the elevator and it stops between floors, door fail to open, or elevator does not stop, etc., do the following: 1. REMAIN CALM - The elevator is stable and will not fall. 2. Use the telephone in the elevator and explain what problems you are having. Tell the security dispatcher which elevator you are in. 3. DO NOT try to force the elevator doors open. 4. Stay on the phone until Security arrives and follow their instructions. 5. Remember: you are not in any danger. 6. Never try to climb out of elevator.

5-4 Updated May 2017 7. In the case of a power failure, the emergency lighting will come on inside the elevator.

Power Failure

Should a power failure occur, call Security Dispatcher X6351 and Plant Operations X6750. It is recommended that you turn off all computer equipment. This will lessen the electrical load on circuits in the building when power is restored. An emergency generator system will provide the necessary power for emergency lighting in the stairwells and corridors. 1. Identify and assist those persons who may need special assistance in evacuating the building. A. It is suggested that wheelchair occupants or persons with mobility impairment should prepare for emergencies ahead of time. B. During an emergency, persons who need special assistance should move to the nearest stairwell and ask for assistance from others. C. If assistance is not immediately available, stay in the exit corridor and call for help. D. When Security or Rescue Personnel arrive they will first check the exit corridors and exit stairwells for trapped persons.

Evacuation When the fire alarm sounds and an evacuation are ordered, all personnel within the building will be instructed to evacuate the building: 1. DO NOT USE THE ELEVATORS - the elevators may be controlled by trained search teams or may be reserved for evacuation of handicapped persons. 2. Walk quickly - DO NOT RUN - to the nearest stairway exit. 3. Keep to the right - in single file - in halls and stairways, so that emergency personnel can gain access to the floor where the incident has been reported. Use handrails when proceeding downstairs. 4. Merge alternately when two groups meet at various floor landings. 5. If possible, provide assistance to any elderly or handicapped persons.

Evacuate to a safe distance from the building - AT LEAST 300 FEET AWAY FROM THE BUILDING. Flying glass or other debris is also cause for damage or injury. DO NOT LINGER IN THE VICINITY OF THE BUILDING. 1. Identify and assist those persons who may need special assistance in evacuating the building. A. It is suggested that wheelchair occupants or persons with mobility impairment should prepare for emergencies ahead of time. B. During an emergency, persons who need special assistance should move to the nearest stairwell and ask for assistance from others.

5-5 Updated May 2017 C. If assistance is not immediately available, stay in the exit corridor and call for help. D. When Security or Rescue Personnel arrive they will first check the exit corridors and exit stairwells for trapped persons.

In Case Of Fire For Fire inside Your Office 1. Call PCOM Security at X6911 2. Sound the building Fire Alarm by pulling the Manual Station as you exit the building will alert PCOM Security Personnel and not the Philadelphia Fire Department. These pull stations are located on each floor by the emergency exits.

A. Close all doors - leave unlocked (take your keys with you). B. DO NOT USE ELEVATORS -use stairwells to exit. (Stairwells are fire rated for 2 hours) 3. Do not try and extinguish the fire.

For Fire outside Your Office 1. Feel the door - if it is HOT, DO NOT OPEN IT. A. Call PCOM Security at X6911 - give them your exact location and describe what's burning and the situation. B. Seal the bottom of the door as best you can with cloth material to keep out smoke. C. Close as many doors between you and the fire as possible. 2. If the door is not hot - open it cautiously and be prepared to close it fast. 3. Walk to the nearest stairwell. A. DO NOT use elevators! B. Alert others. C. If there is smoke present, stay low. D. Walk down the stairwell - do not run - go up ONLY when downward movement is not safe. 4. Identify and assist those persons who may need special assistance in evacuating the building. 5. It is suggested that wheelchair occupants or persons with mobility impairment should prepare for emergencies ahead of time. 6. During an emergency, persons who need special assistance should move to the nearest stairwell and ask for assistance from others. 7. If assistance is not immediately available, stay in the exit corridor and call for help. 8. When Security or Rescue Personnel arrive they will first check the exit corridors and exit

5-6 Updated May 2017 stairwells for trapped persons. 9. Security, Plant Operations, Safety Coordinator, or the Philadelphia Fire Department will give you evacuation orders. If evacuated, move at least 300 feet from the building. PLAN AHEAD! KNOW ALL EXIT STAIRWELL LOCATIONS! DO NOT USE ELEVATORS!

Fire Extinguishers

DO NOT USE FIRE EXTINGUISHERS UNLESS YOU HAVE EXPERIENCE AND/OR TRAINING WITH THE PROPER USE OF THEM - Each floor has portable fire extinguishers located in the hallway by stairwell exit doors. If you ever need to depend on this equipment, make sure that you take time to learn its capabilities, limits, and basic operation. (These Fire Extinguishers are examined and recharged annually).

5-7 Updated May 2017 Emergency Procedures – GA Campus

This is your Emergency Hazard Communication Procedures Manual. The document is a collaborative effort of the Security and Public Safety and Plant Operations departments and was recently endorsed by the members of the Institutional Environmental Health and Safety Committee. In the event of a fire, accident, illness or other emergency, the directions provided within will enable you to react appropriately and safety. All members of your staff should be familiar with these procedures. It is recommended that this information be posted in your work areas. Please note that in all emergency situations, the Security Department/Dispatcher must be notified.

This material has been prepared by the Philadelphia College of Osteopathic Medicine, Philadelphia College of Osteopathic Medicine the Georgia Campus and the Department of Security and Public Safety.

Directory PCOM Security Emergency ...... X7451 Basic Science Lab Technician ...... X7567 School of Pharmacy Lab Technician………………… X2775 Anatomy Technician ...... X7477

Accident or Illness In the event of an accident or illness of an employee, student, or visitor in your area, we recommend that you: 1. Call PCOM Security Dispatcher at X7451 Give the dispatcher the following information: A. Your location B. Any details available of the accident or illness 2. DO NOT try to move the injured or ill person. Simply try to make them comfortable until emergency help arrives.

Power Failure Should a power failure occur, call Security Dispatcher X7451. It is recommended that you turn off all computer equipment. This will lessen the electrical load on circuits in the building when power is restored. An emergency generator system will provide the necessary power for emergency lighting in the corridors and lab spaces. 1. Identify and assist those persons who may need special assistance in evacuating the building. A. It is suggested that wheelchair occupants or persons with mobility impairment should prepare for emergencies ahead of time. B. During an emergency, persons who need special assistance should move to the nearest exit and ask for assistance from others. C. If assistance is not immediately available, stay in the exit corridor and call for help. D. When Security or Rescue Personnel arrive they will first check the exit corridors for trapped persons.

5-8 Updated May 2017

Evacuation When the fire alarm sounds and an evacuation is ordered, all personnel within the building will be instructed to evacuate the building:

1. Walk quickly - DO NOT RUN - to the nearest exit. 2. Keep to the right - in single file - in halls, so that emergency personnel can gain access to the floor where the incident has been reported. 3. If possible, provide assistance to any elderly or handicapped persons. Evacuate to a safe distance from the building - AT LEAST 300 FEET AWAY FROM THE BUILDING. Flying glass or other debris is also cause for damage or injury.

DO NOT LINGER IN THE VICINITY OF THE BUILDING.

In Case Of Fire

For Fire inside Your Office 1. Call PCOM Security at X7451 2. Sound the building Fire Alarm by pulling the Manual Station as you exit the building will alert PCOM Security Personnel. These pull stations are located by the emergency exits. A. Close all doors - leave unlocked (take your keys with you). 3. Do not try and extinguish the fire.

For Fire outside Your Office 1. Feel the door - if it is HOT, DO NOT OPEN IT. A. Call PCOM Security at X7451 - give them your exact location and describe what's burning and the situation. B. Seal the bottom of the door as best you can with cloth material to keep out smoke. C. Close as many doors between you and the fire as possible. 2. If the door is not hot - open it cautiously and be prepared to close it fast. 3. Walk to the nearest exit. A. Alert others. B. If there is smoke present, stay low. 4. Identify and assist those persons who may need special assistance in evacuating the building. 5. It is suggested that wheelchair occupants or persons with mobility impairment should prepare for emergencies ahead of time. 6. If assistance is not immediately available, stay in the exit corridor and call for help. 7. When Security or Rescue Personnel arrive they will first check the exit corridors for trapped persons. 8. Security, School Operations, Safety Coordinator or the Gwinnett Fire Department will give you evacuation orders. If evacuated, move at least 300 feet from the building. PLAN AHEAD! KNOW ALL EXITS!

5-9 Updated May 2017 Fire Extinguishers DO NOT USE FIRE EXTINGUISHERS UNLESS YOU HAVE EXPERIENCE AND/OR TRAINING WITH THE PROPER USE OF THEM - Each floor has portable fire extinguishers located in the hallway by stairwell exit doors. If you ever need to depend on this equipment, make sure that you take time to learn its capabilities, limits and basic operation. (These Fire Extinguishers are examined and recharged annually).

5-10 Updated May 2017 Part 6. Radiation Safety

Philadelphia College of Osteopathic Medicine Occupational and Environmental Safety Department

RADIATION SAFETY Radiation Safety Program: Consistent with regulations of the United States Nuclear Regulatory Commission, the Pennsylvania Department of Environmental Resources (PaDER), the United States Environmental Protection Agency (EPA), and the recommendations of the International Commission on Radiological Protection (ICRP), and the National Council on Radiation Protection and Measurements (NCRP), the Radiation Safety Office of the Philadelphia College of Osteopathic Medicine has a program for the control of radiation-producing machines. Elements of the radiation safety program and ensuing policies are included in the following sections of this document. Authorized users and other personnel that are involved with the use of radioactive material and radiation-producing machines should be familiar with this document The policies covered by this document are subject to change without notice. This document is subject to revision as Radiation Safety policies change. The most current copy of this document and copies of the PaDER license are available for inspection in the PCOM Occupational and Environmental Safety Department.

PCOM does not have a current license to possess, use, and store radioactive materials.

Radiation Safety Officer: The Radiation Safety Officer is responsible for implementation of the Radiation Safety Program at PCOM. In that capacity, the Radiation Safety Officer ensures that all activities involving x-ray producing machines and equipment capable of producing ionizing and non-ionizing electromagnetic radiation are performed in accordance with approved policies and regulatory requirements. The Radiation Safety Officer is authorized to stop an operation if, in the Radiation Safety Officer's judgment, the operation is in violation of PCOM radiation safety policies. Furthermore, the Radiation Safety Officer may require specific actions to assure compliance with PCOM policies and Federal and Pennsylvania regulations.

Responsibilities of the Radiation Safety Officer: • General surveillance of all radiation safety activities, including investigations of over exposures, accidents, spills, losses, thefts, unauthorized receipts, uses, transfers, disposals, and other deviations from approved radiation safety practices and implementation of corrective actions; • Evaluate equipment, physical facilities, operational techniques and procedures; • Recommend and evaluate personnel monitoring equipment, establish requirements for 6-1 Updated April 2017 bioassay and special monitoring procedures, and maintaining records of personnel exposure; • Assure that personnel who work in, or frequent areas where radiation producing equipment receive appropriate training; • Maintain oversight of disposal of radioactive waste and maintain required disposal records; • Actively participate in the PCOM IEHS Committee; • Ensure that all license commitments and regulatory requirements have been met; • Manage the operation of the PCOM Radiation Safety Office.

Radiation Safety Training: The personnel training program will be given to all personnel who work with or in the vicinity of radiation-producing machines. The training will be in the form of procedures manuals and private instruction. The training program will be of sufficient scope to ensure that all personnel including technical, clerical, housekeeping, and security personnel receive proper instruction in the items specified in applicable regulations: A. Areas where radiation-producing machines are used. B. Potential hazards associated with radiation-producing machines. C. Radiation Safety procedures appropriate to their respective duties. D. Pertinent State regulations. E. Their obligation to report unsafe conditions. F. Appropriate response to emergencies or unsafe conditions. G. Locations where the licensee has posted or made available notices, copies of pertinent licenses and license conditions (including applications and applicable correspondence).

Personnel will be properly instructed as follows:

A. Before assuming duties with or in the vicinity of radiation-producing machines. B. During annual refresher training. C. Whenever there is a significant change in duties, regulations, or the terms of the license. Please contact for further assistance:

Nate Pinkney Chief Occupational/Environmental Safety Officer office 215-871-6360 | cell 215-872-0174 | fax 215-871-6359 Email: [email protected]

Pamela Vu, MPH Occupational Safety Specialist office 215-871-6150 | fax 215-871-6359 Email: pamelavu@pcom

6-2 Updated April 2017 Part 7. Laser Safety

Philadelphia College of Osteopathic Medicine Occupational and Environmental Safety Department

LASER SAFETY Laser Safety Program: The Laser Safety Office of the Philadelphia College of Osteopathic Medicine has a program to control the use of laser producing devices. Elements of the laser safety program and ensuing policies are included in the following sections of this Policy Manual. Authorized users and other personnel that are involved with the use of laser producing equipment should be familiar with this Policy Manual. Copies of this manual shall be made available for all users. The policies covered by this manual are subject to change without notice. This manual is subject to revision as Laser Safety policies change.

Laser Energy Each laser system has its own unique set of optical properties, controls, and output characteristics. The majority of medical lasers are Class IV (surgical) or Class III (non-surgical) devices, which emit laser radiation considered hazardous to the skin and eye, and include dermatologic, ophthalmic, and some therapeutic lasers. “Cold lasers” are Class IV or Class III therapeutic lasers that use low-intensities or low levels of laser light. Class II lasers, such as HeNe (helium-neon) lasers, whose visible red radiation is used in aiming the invisible radiation of CO2 (carbon dioxide) and Nd:YAG (neodymium: yttrium-aluminum-garnet) lasers, present a hazard when viewed directly for extended periods or at regular intervals. Class I lasers, such as those used for positioning and alignment during radiographic examination and treatment, are not considered hazardous. The Center for Devices and Radiological Health (CDRH) of the Food and Drug Administration (FDA) and the Occupational Safety and Health Administration (OSHA) require all but Class I lasers to display warning labels alerting users to recommended protective measures, such as the use of laser safety eyewear (LSE). In addition, the American National Standard for the Safe Use of Lasers (ANSI Z136.1.) requires that, in a facility where lasers are used, a laser safety committee oversee selection, purchase, and use of lasers within the institution. It also requires that a laser safety officer be designated to monitor and enforce the safe use of lasers, determine laser hazards, and establish controls to mitigate those hazards — including the use of LSE. The laser safety officer’s directives should be rigorously followed by all personnel, including surgical and service staff.

7-1 Updated April 2017

Laser Safety Officer: The Laser Safety Officer (LSO) is responsible for implementation of the Laser Safety Program at PCOM. In that capacity, the Laser Safety Officer ensures at all activities involving laser producing equipment are performed in accordance with approved policies and regulatory requirements. The Laser Safety Officer is authorized to stop an operation if, in the Laser Safety Officer's judgment, the operation is in violation of PCOM laser safety policies. Furthermore, the Laser Safety Officer may require specific actions to assure compliance with PCOM policies and Federal and Pennsylvania regulations.

Responsibilities of the Laser Safety Officer: General surveillance of all laser safety activities, including investigations errors and implementation of corrective actions; Ensure that lasers are used only in controlled areas which are limited to essential personnel in proper personal protective equipment (PPE) Evaluate equipment, physical facilities, operational techniques and procedures; Assure that personnel who work in, or frequent areas where laser producing equipment is used, receive appropriate training; Prepare an annual report on the laser safety program; Actively participate in the PCOM IEHS committee.

Area Controls Lasers should be used only in controlled areas. Entry into the laser use area should be limited to essential personnel, who must don protective eye wear before entering during a laser procedure. Windows located in the laser-use area must be covered with material that is non-reflective and prevents light energy of the wavelength being used from escaping the room. Covering the windows also precludes any risk of harm to an outsider who might look into the laser-use area.

Various signs (e.g., standard laser hazard symbol) and signals should be employed to alert personnel that the laser is being used. During most procedures, the laser is being used only a fraction of the time. Within the laser-use area, an audible tone from the laser should alert staff of the imminent activation of the laser beam. Signs must be posted on all doors entering the laser- use area. Appropriate protective eyewear should be clearly marked and readily available outside the laser-use area.

7-2 Updated April 2017

Reflected Laser Energy To eliminate the risk of unintentional reflection of the laser beam, a thorough examination for reflective surfaces must be conducted on all materials and instruments that will be present during laser procedures, and reflective materials that might be in the laser’s path should be identified and replaced, modified, or covered. Sometimes, an instrument that appears non-reflective to the naked eye is, in fact, reflective to infrared radiation; special non-reflective instruments may be purchased and used for laser surgery.

Eye Protection Reports of eye damage invariably involve personnel not using protective eye wear. Protective eye wear with appropriate filtering capabilities and optical density is recommended. Spectacles with side shields should be worn by all personnel in the laser-use area whenever the laser is activated. Protective eye wear recommendations vary with the wavelength and the power density of the laser energy in use; for example, eye wear to filter the CO2 laser beam will be totally inadequate when the Nd:YAG laser is used. The American National Standards Institute (ANSI) Standard Z136.1 recommends light-tight goggles, but wearer discomfort, reduced visibility, fogging, and tunnel vision are common complaints. Comfort and peripheral vision outweigh the very remote possibility of damage to the eye by back reflection or side entrance of a stray beam. With side shields, properly fitted, lightweight laser-protective spectacles provide a good alternative to goggles if discomfort might result in their not being worn. Side shields made of the same material as the lenses allow good peripheral vision as well. Protective eye wear is selected with several parameters in mind: the laser’s wavelength or wavelength range, the filter’s optical density for that wavelength, and the laser’s power density. The optical density of the protective filters must be adequate to provide protection, but need not be so dark as to reduce visibility (i.e., greater optical density is not always better). When choosing protective filters, the required optical density is determined by the maximum irradiance to which the wearer is likely to be

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exposed. The supplier of the laser will be able to advise the user on proper eye wear selection. In cases of research lasers or lasers that have been altered from their original design, the laser safety officer will be responsible for determining specifications for appropriate eye wear. Protective spectacles should allow prolonged wear without eyestrain, even during detailed work.

Eye Protection during Surgery During microscopic and endoscopic laser surgery, automatic shutter systems place protective filters in the line of sight during laser operation. These shutters have, on occasion, failed, causing damage to the surgeon’s eyes. Except when special protocols have been established for specific surgical procedures, laser delivery through microscope optics does not preclude the need for protective eye wear for the rest of the staff, and surgeons using an endoscope with protective filters must wear a protective lens for the other eye. Misdirection of the beam due to disconnection of the articulated arm, a break in the fiber optic cable, or specular (mirror-like) reflection of the beam from a shiny surface (e.g., surgical instruments, flat-surface spectacles) could expose those nearby to hazardous laser energy.

Eye Examinations The World Health Organization (WHO) and ANSI recommend eye exams for all persons assigned to laser-use areas: one exam at the start of employment, to establish a baseline medical record, and another exam at the termination of employment. Some recommend regular examinations, but the WHO Working Group concluded that these exams may prove inconclusive since some lesions may not be detected even by experienced clinicians or may be indistinguishable from lesions due to other causes. Examinations are, however, recommended as part of all incident investigations whenever laser exposure is suspected.

Skin Damage The skin is also subject to injury by Class III and Class IV laser radiation, and injury may be more likely simply because the skin has a greater exposed surface area than the eye. Accidental exposure is painful but less likely to be disastrous than eye exposure. Depending on the length of the exposure, the energy density of the beam, and the color of the skin, damage varies from a localized reddening to charring of the exposed skin. The primary mechanism of tissue damage is thermal. Increasing temperature causes protein denaturation and tissue death, boiling of cellular components and vaporization of the cells, and burning of the dry tissue with char formation. These effects are largely exposure-time dependent. There have been no recommendations for laser-proof protective clothing, but non-target patient tissues should routinely be protected by saline-saturated dressings with consideration for sterile technique. To protect skin against

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exposure to laser plume and tissue debris, the usual surgical attire: gloves, gown (covering the arms), cap, and mask are recommended.

Personal Protection: Respirators Standard surgical masks, even when two are worn, are inadequate protection against laser plume inhalation. Special masks designed to filter particles as small as 0.3 µm are currently available, but they can hinder breathing and become less effective after extended use. In the absence of proper smoke evacuation, a tight-fitting mask known as a respirator, with filter pore sizes less than 0.12 µm is currently accepted as adequate protection against particles in the laser plume. However, a respirator can be bulky and uncomfortable to wear and is not favored by surgeons. In addition some of these masks filter gases. With the availability of smoke evacuators to control laser plume, the use of respirators during laser or ESU procedures may not be necessary.

Fire Prevention Fire prevention requires an awareness of the potential risks, the exercise of appropriate caution, and precise control of the laser beam. Fire can be started by the reflection of the beam as well as the direct beam itself; and some reflective surfaces can focus the beam, making it potentially more harmful. Strict safety protocols should be followed: • The laser should be in the standby mode at all times except when the hand piece or other delivery system is in the surgeon’s hand. • When in standby mode, do not allow the hot fiber tip to touch surgical drapes or any other flammable substances. • Make sure that pockets of combustion-supporting gases do not build up under surgical drapes

Fire Control When a fire occurs, immediate action on the part of staff will minimize injury to the patient and staff. A basin of sterile water or sterile saline and a syringe should be readily available to douse a small fire and to keep protective dressings wet (dry gauze and cottonoid sponges are readily ignited by the laser). Drapes or towels should be available to smother flames on the patient.

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Portable fire extinguishers should be mounted in convenient locations (e.g., by the door of each room) and personnel should be trained in proper technique.

Please contact for further assistance: Nate Pinkney Chief Occupational/Environmental Safety Officer office 215-871-6360 | cell 215-872-0174 | fax 215-871-6359 Email: [email protected]

Pamela Vu, MPH Occupational Safety Specialist office 215-871-6150 | fax 215-871-6359 Email: [email protected]

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Part 8. Health and Safety Issues for the Basic Sciences

PURPOSES: • To have day-to-day laboratory operations in conformity with PCOM policies and OSHA regulations • To have safety consciousness in laboratory practice • To facilitate the ordering, storing, handling, use, and disposal of chemicals and their wastes • To present information in the event of injury, spills, or emergencies • To impress on the need for incident reporting

SCOPE: This policy applies to all personnel (faculty, students, technicians, and technologists) who work in any capacity and for any length of time in the research laboratory.

Laboratory Dress Code: This dress code applies specifically to laboratory workers and does not supplant general dress codes and guidelines established by PCOM Human Resources or other PCOM departments.

• Clothing worn by laboratory workers should be clean, neat and in good repair. • Clothing worn in the lab should provide protection to the skin in the event of a chemical splash or spill. This requires a long sleeved laboratory coat (buttoned closed) or a back closed gown. According to OSHA laboratory standards, personnel should not wear loose (e.g., dangling neckties, and overly large or ragged laboratory coats), skimpy (e.g., shorts, strapless, cropped or halter tops), or torn clothing. Short trousers or miniskirts are inappropriate laboratory attire because laboratory coats open in the front when a person sits thereby exposing the legs above the knees to potential spills. • Shoes should be fluid impermeable material, leather or synthetic, and should cover the entire foot. Shoes with open toes are unacceptable while in the lab. Because cloth shoes will absorb chemicals or infectious fluids, they are not recommended. • Avoid wearing contact lenses in the laboratory unless necessary.

………………………………………………………………………………………………… Eating and Drinking in the Lab: • Eating, drinking, chewing gum, applying cosmetics, taking medications, handling contact lenses or similar activities in laboratories may result in the accidental exposure to hazardous materials (chemical radiological, biological); therefore these activities are strictly prohibited in all PCOM laboratory spaces. • Persons must wash their hands after working with potentially hazardous materials and before leaving the laboratory. • Food must be stored outside the laboratory area in cabinets or refrigerators designated 8-1 Updated April 2017

and used for this purpose. ………………………………………………………………………………………………… Personal Protective Equipment: • Personal Protective Equipment (PPE) such as fluid resistant gowns, gloves, goggles, face masks, face shields should be available and are required when there is significant probability that potentially hazardous substances may be splashed on the worker. • Regardless of the reason for wearing them, contact lenses do not fulfill the personal protective equipment requirements for ocular safety when worn by individuals performing eye hazardous tasks. OSHA requires individuals who wear contact lenses in the workplace to combine them with appropriate industrial safety eyewear. ………………………………………………………………………………………………… Blood-borne pathogens: • All biological safety cabinets (hoods) are checked/maintained annually by an outside vendor. …………………………………………………………………………………………………. Chemical safety:

• Chemicals should be ordered for immediate use. Reserve supplies of acids, bases, and solvents may be stored according to the manufacturer’s recommendations or the expiration date on the label.

• Acids should be stored in a blue cabinet with inorganic acids placed on a shelf separate from organic acids. Solvents should be placed in a yellow cabinet. Solvent cabinets must be vented to the outside. Liquid bases may be stored under a chemical hood. • Chemical hoods are regularly checked/maintained by Plant Operations. Contact the Supervisor (6755) or Director (x6750 for PA campus and x7458 for GA campus), with any concerns/problems. • Information on the proper handling, use, safety, and disposal of chemicals is in the Safety Data Sheets (SDS). • Copies of appropriate SDS should be in the area of use and in the area of storage. Also, SDS copies used by all department personnel should be placed, bound, in a central accessible area. In addition, copies of all SDS should be sent to the Support Specialist for Plant Operations (x6750 for PA campus and x7458 for GA campus). • Once a year, usually in the fall or winter, updates for departmental chemicals lists are requested by the Support Supervisor for Plant Operations (x6750 for PA campus and x7458 for GA campus). Copies of the departmental chemicals lists should be retained in each laboratory, in a central accessible area, and sent to the Support Supervisor for Plant Operations. …………………………………………………………………………………………………. Disposal: • All used/unused chemicals must be disposed according to directions stated on SDS. • Hazardous chemicals and/or byproducts that cannot be disposed of on the premises are to be labeled and safely packaged centrally for annual pick-up usually in the winter. All

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departments are notified by Plant Operations (x6750 for PA campus) and (x7458 for GA campus), as to the date of pick-up. Prior to the removal of the chemicals, each department must submit to the Support Specialist for Plant Operations (x6750 for PA campus and x7458 for GA campus), a list specifying chemical or mixture name, quantity, container type, and place of storage. • Items in the Red bag and Sharps container may be retained in the laboratory for up to a maximum of 30 days. After this time the bags and containers, whether full or not, are to be disposed in a proper way. • For autoclaving, only use bags having a heat-sensitive symbol or wording that clearly states that the contents are "sterile". Place each cooled autoclaved bag into a separate black or brown trash bag for regular trash pick-up. …………………………………………………………………………………………………. Spills: Each department maintains one or more spill control centers. Chemical spills, must be promptly contained and absorbed. Therefore, a spill control center must have such items as universal pillows, disposable aprons, absorbing/neutralizing agents for acids, bases, solvents, and formaldehyde/paraformaldehyde, mercury storage containers, full-face respirator, safety goggles, and gloves. The absorbed material must be scooped up and placed into a plastic bag for regular trash disposal. Hazardous substance spills, regardless of type and amount, must be reported immediately to the PCOM Security Dispatcher, x6351 (PA Campus) and x7451 (GA Campus). …………………………………………………………………………………………….

Accidents: • Each laboratory should be equipped with arm-operated eyewash devices. Employees must know where the closest eyewash station is and how to get there with restricted vision. These are checked weekly in-house. • Each laboratory should have a fire extinguisher, inspected monthly in-house and serviced annually, that works against paper/wood, electrical, and oil fires. • Each department should have one deluge shower, located in the hallway or in a convenient laboratory. The location of the shower is marked by an outward projecting green-on-white sign. • At least one first-aid box must be strategically placed for all personnel. Usual use is for minor cuts, scrapes, and burns, requiring only antibiotic ointment and Band-Aid application. • In all cases, an Employee Incident Report form, from the department secretary, must be filled out and filed with Risk Management. …………………………………………………………………………………………………. Emergencies: • For non-life-threatening injuries, Student Wellness Center (6420) is located in room 311 in the Medical Office Building (from 8:00 am to 4:00 pm). • For a life-threatening injury/situation, Security should be notified at 6911. • In all cases, an Employee Incident Report form, from the department secretary, must be filled out and filed with Risk Management. 8-3 Updated April 2017

• Please alert Security as to any personnel working after normal hours. …………………………………………………………………………………………………. Training:

• Most of the contents of this Policy for Basic Science personnel can be communicated during annual safety seminars. • Specific training in the use of chemicals and animals in research should be acquired from specifically experienced/trained personnel. • Demonstration on the proper use of the autoclave will be performed on an as-needed basis. …………………………………………………………………………………………………. Record-keeping: • Each researcher should contribute to the maintenance of the laboratory chemicals list. A departmental chemicals list must be kept in a central area. • Each laboratory and storage area must have its complement of appropriate SDS. A copy of all SDS must be kept in a central area. • A record must be maintained in the form of a dated roster of attendees for each annual safety seminar. …………………………………………………………………………………………………. Responsibilities:

• The mentor of each laboratory must see that all laboratory personnel, before they start any research work, have a History/Physical on file at Student Health Services and an evaluation as to the need for the Hepatitis B vaccination series. • The laboratory mentor must procure the needed SDS for the laboratory. Copies must be used in the storage area, if applicable, in the central departmental area, and sent to the Chief Occupational/Environmental Safety Officer ([email protected]).

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Appendix A Philadelphia College of Osteopathic Medicine Occupational and Environmental Safety Department

Guidelines for Biosafety Level 2 Laboratory Facilities & Operations

Biosafety Level 2 (BSL-2):

Biosafety Level 2 builds upon BSL-1. BSL-2 is suitable for work involving agents that pose moderate hazards to personnel and the environment. It differs from BSL-1 in that 1) laboratory personnel have specific training in handling pathogenic agents and are supervised by scientists competent in handling infectious agents and associated procedures; 2) access to the laboratory is restricted when work is being conducted.

Prior to beginning research where BSL-2 materials (e.g., viruses, bacterium, and recombinant DNA) are used, approval of the Occupational & Environmental Safety Department is required.

Standard Microbiological Practices for BSL-2

Individuals who are responsible for supervising the laboratory must enforce the institutional policies that control access to the laboratory.

Individuals must wash their hands after working with potentially hazardous materials and before leaving the laboratory.

Eating, drinking, smoking, handling contact lenses, applying cosmetics, and storing food for human consumption must not be permitted in laboratory areas. Food must be stored outside the laboratory area in cabinets or refrigerators designated and used for this purpose.

Mouth pipetting is prohibited; mechanical pipetting devices must be used.

Policies for the safe handling of sharps, such as needles, scalpels, pipettes, and broken glassware must be developed and implemented. Whenever practical, laboratory supervisors should adopt improved engineering and work practice controls that reduce risk of sharps injuries. Precautions, including those listed below, must always be taken with sharp items including:

• Careful management of needles and other sharps are of primary importance. Needles must not be bent, sheared, broken, recapped, removed from disposable syringes, or otherwise manipulated by hand before disposal.

. Used disposable needles and syringes must be carefully placed in conveniently located puncture-resistant containers used for sharps disposal. . Non-disposable sharps must be placed in a hard walled container for transport to a processing area for decontamination, preferably by autoclaving.

• Broken glassware must not be handled directly. Instead, it must be removed using a brush and 8-5 Updated April 2017

dustpan, tongs, or forceps. Plastic ware should be substituted for glassware whenever possible.

Perform all procedures to minimize the creation of splashes and/or aerosols.

Decontaminate work surfaces after completion of work and after any spill or splash of potentially infectious material with appropriate disinfectant.

Decontaminate all cultures, stocks, and other potentially infectious materials before disposal using an effective method.

• Materials to be decontaminated outside of the immediate laboratory must be placed in a durable, leak proof container and secured for transport.

• Materials to be removed from the facility for decontamination must be packed in accordance with applicable local, state, and federal regulations.

A sign incorporating the universal biohazard symbol must be posted at the entrance to the laboratory when infectious agents are present. Posted information must include: the laboratory’s biosafety level, the supervisor’s name (or other responsible personnel), telephone number, and required procedures for entering and exiting the laboratory. Agent information should be posted in accordance with the institutional policy.

An effective integrated pest management program is required.

The laboratory supervisor must ensure that laboratory personnel receive appropriate training regarding their duties, the necessary precautions to prevent exposures, and exposure evaluation procedures. Personnel must receive annual updates or additional training when procedural or policy changes occur. Personal health status may impact an individual’s susceptibility to infection, ability to receive immunizations or prophylactic interventions. Therefore, all laboratory personnel and particularly women of child-bearing age should be provided with information regarding immune competence and conditions that may predispose them to infection. Individuals having these conditions should be encouraged to self- identify to the institution’s healthcare provider for appropriate counseling and guidance.

Special Practices

All persons entering the laboratory must be advised of the potential hazards and meet specific entry/exit requirements.

Laboratory personnel must be provided medical surveillance and offered appropriate immunizations for agents handled or potentially present in the laboratory.

Each institution must establish policies and procedures describing the collection and storage of serum samples from at-risk personnel.

A laboratory-specific biosafety manual must be prepared and adopted as policy. The biosafety manual must be available and accessible.

The laboratory supervisor must ensure that laboratory personnel demonstrate proficiency in standard and special microbiological practices before working with BSL-2 agents. 8-6 Updated April 2017

Potentially infectious materials must be placed in a durable, leak proof container during collection, handling, processing, storage, or transport within a facility. Laboratory equipment should be routinely decontaminated, as well as, after spills, splashes, or other potential contamination.

• Spills involving infectious materials must be contained, decontaminated, and cleaned up by staff properly trained and equipped to work with infectious material.

• Equipment must be decontaminated before repair, maintenance, or removal from the laboratory.

Incidents that may result in exposure to infectious materials must be immediately evaluated and treated according to procedures described in the laboratory biosafety safety manual. All such incidents must be reported to the laboratory supervisor. Medical evaluation, surveillance, and treatment should be provided and appropriate records maintained.

Animals and plants not associated with the work being performed must not be permitted in the laboratory.

All procedures involving the manipulation of infectious materials that may generate an aerosol should be conducted within a BSC or other physical containment devices.

Safety Equipment (Primary Barriers and Personal Protective Equipment)

Properly maintained BSCs (preferably Class II), other appropriate personal protective equipment, or other physical containment devices must be used whenever:

Procedures with a potential for creating infectious aerosols or splashes are conducted. These may include pipetting, centrifuging, grinding, blending, shaking, mixing, sonicating, opening containers of infectious materials, inoculating animals intranasally, and harvesting infected tissues from animals or eggs.

High concentrations or large volumes of infectious agents are used. Such materials may be centrifuged in the open laboratory using sealed rotor heads or centrifuge safety cups.

Protective laboratory coats, gowns, smocks, or uniforms designated for laboratory use must be worn while working with hazardous materials. Remove protective clothing before leaving for non-laboratory areas (e.g., cafeteria, library, administrative offices). Dispose of protective clothing appropriately, or deposit it for laundering by the institution. It is recommended that laboratory clothing not be taken home.

Eye and face protection (goggles, mask, face shield or other splatter guard) is used for anticipated splashes or sprays of infectious or other hazardous materials when the microorganisms must be handled outside the BSC or containment device. Eye and face protection must be disposed of with other contaminated laboratory waste or decontaminated before reuse. Persons who wear contact lenses in laboratories should also wear eye protection.

Gloves must be worn to protect hands from exposure to hazardous materials. Glove selection should be based on an appropriate risk assessment. Alternatives to latex gloves should be available. Gloves must not be worn outside the laboratory. In addition, BSL-2 laboratory workers should:

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• Change gloves when contaminated, integrity has been compromised, or when otherwise necessary. Wear two pairs of gloves when appropriate.

• Remove gloves and wash hands when work with hazardous materials has been completed and before leaving the laboratory.

• Do not wash or reuse disposable gloves. Dispose of used gloves with other contaminated laboratory waste. Hand washing protocols must be rigorously followed.

Eye, face and respiratory protection should be used in rooms containing infected animals as determined by the risk assessment.

Laboratory Facilities (Secondary Barriers)

Laboratory doors should be self-closing and have locks in accordance with the institutional policies.

Laboratories must have a sink for hand washing. The sink may be manually, hands-free, or automatically operated. It should be located near the exit door.

The laboratory should be designed so that it can be easily cleaned and decontaminated. Carpets and rugs in laboratories are not permitted.

Laboratory furniture must be capable of supporting anticipated loads and uses. Spaces between benches, cabinets, and equipment should be accessible for cleaning.

• Bench tops must be impervious to water and resistant to heat, organic solvents, acids, alkalis, and other chemicals.

• Chairs used in laboratory work must be covered with a non-porous material that can be easily cleaned and decontaminated with appropriate disinfectant.

Laboratory windows that open to the exterior are not recommended. However, if a laboratory does have windows that open to the exterior, they must be fitted with screens.

BSCs must be installed so that fluctuations of the room air supply and exhaust do not interfere with proper operations. BSCs should be located away from doors, windows that can be opened, heavily traveled laboratory areas, and other possible airflow disruptions.

Vacuum lines should be protected with High Efficiency Particulate Air (HEPA) filters, or their equivalent. Filters must be replaced as needed. Liquid disinfectant traps may be required.

An eyewash station must be readily available.

There are no specific requirements on ventilation systems. However, planning of new facilities should consider mechanical ventilation systems that provide an inward flow of air without recirculation to spaces outside of the laboratory.

HEPA filtered exhaust air from a Class II BSC can be safely re-circulated back into the laboratory

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environment if the cabinet is tested and certified at least annually and operated according to manufacturer’s recommendations. BSCs can also be connected to the laboratory exhaust system by either a thimble (canopy) connection or a direct (hard) connection. Provisions to assure proper safety cabinet performance and air system operation must be verified.

A method for decontaminating all laboratory wastes should be available in the facility (e.g., autoclave, chemical disinfection, incineration, or other validated decontamination method).

Emergency exposure procedures

Note: After any exposure to BSL-2 materials via skin, inhalation, ingestion, or eye contact the victim should immediately seek medical evaluation.

PCOM employees: All illnesses or injuries related to exposure to BSL-2 materials must be reported to PCOM’s Risk Management within 24 hours of occurrence. An Incident Report should be filled out as soon as possible.

Philadelphia employees receive treatment at: WORKNET Occupational Medicine 5800 Ridge Avenue, Suite 234 Philadelphia, PA 19128 (215) 487-4540

In Georgia, employees must be seen by a physician listed on the workers’ compensation carrier’s approved listing.

PCOM students: All illnesses related to exposure to BSL-2 materials must be reported to PCOM’s Student Wellness within 24 hours of occurrence. An Incident Report should be filled out as soon as possible.

Philadelphia students receive treatment at:

Advanced Urgent Care 5058 City Avenue Philadelphia, PA 19131 Phone: (215) 921-6369 or Any Advanced Urgent Care location

Georgia students receive treatment at:

Gwinnett Medical Center 1000 Medical Center Blvd. NW Lawrenceville, GA 30045 Phone: (678) 312-2920

Physicians Immediate Med 3425 Buford Drive Buford, GA 30519 Phone: (678) 546-0200 8-9 Updated April 2017

In case of a severe illness or injury, or after normal business hours, always seek treatment at the nearest hospital ER.

Individuals working in a BSL-2 environment shall maintain a copy of these guidelines, relevant BSL-2 Safety Data Sheets (SDSs), and a BSL-2 Self-Assessment Safety Checklist.

ACKNOWLEDGEMENT*:

I have read and understand these guidelines pertaining to the performance of duties involving the use of BSL-2 materials. I am aware of the risks involved and will take the necessary precautions when working with these materials.

SIGNATURE: ______

DATE: ______

*A separate acknowledgement must be signed by each individual working in a BSL-2 environment.

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Appendix A Philadelphia College of Osteopathic Medicine Occupational and Environmental Safety Department

Self-Assessment Safety Checklist for Biosafety Level 2 Laboratory Facilities & Operations

This form is intended to aid in assessing a laboratory as appropriate to perform BSL-2 studies.

Facility: ______

Address: ______

______

Room/Lab #: ______

Name of Primary Investigator: ______• This individual must be educated, trained and qualified to supervise and/or perform microbiological projects and maintain the criteria below. • Qualifications: (List or attach additional sheet if necessary. Qualifications should include significant course work in microbiology and/or significant related experience) ______I attest that I have the qualifications listed above (or attached).

SIGNATURE: ______DATE: ______

Name of Laboratory Supervisor: ______• This individual must be educated, trained and qualified to supervise and/or perform microbiological projects and maintain the criteria below. • Qualifications: (List or attach additional sheet if necessary. Qualifications should include significant course work in microbiology and/or significant related experience) ______

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I attest that I have the qualifications listed above (or attached).

SIGNATURE: ______DATE: ______

If you check any of the following boxes with “NO”, you must make appropriate modifications before you can classify the lab as a BSL-2 facility. Safety must be your primary concern.

Check the appropriate box for each statement:

1. Approval of the Occupational & Environmental Safety Department has been obtained for research where BSL-2 materials (e.g., viruses, bacterium, and recombinant DNA) are used. Yes No

2. Access to the laboratory is strictly limited when BSL-2 experiments are in progress. A sign should be placed on the door indicating BSL-2 experiments are in progress. When BSL-2 experiments are not in progress, BSL-2 materials are locked and the BSC and surrounding area is decontaminated. Yes No

3. Biological safety cabinets are certified annually, when cabinets are moved, or when HEPA filters are changed. Yes No

A. Standard Microbiological Practices

1. All personnel wash their hands after they handle viable materials and animals, after removing gloves, and before leaving the laboratory. Yes No

2. Eating, drinking, handling contact lenses, and applying cosmetics are forbidden in the laboratory. Yes No

3. Mouth pipetting is prohibited and only mechanical pipetting devices are used. Yes No

4. All procedures are performed to minimize the creation of splashes or aerosols. Yes No

5. Work surfaces are decontaminated with disinfectant when work is completed at the end of the day and after any spill of viable material. Yes No

6. All contaminated cultures, stocks, glassware, plastic ware and other biologically contaminated waste are treated as biohazardous material to be autoclaved. Yes No

7. Culture fluids and other contaminated liquid wastes are autoclaved or decontaminated with a suitable disinfectant before disposal. Yes No

8. Sharps are discarded in puncture-resistant sharps disposal containers and treated as medical waste according to the institution’s disposal policies. (Sharps include hypodermic syringes and needles, Pasteur pipettes, razor blades, contaminated broken glass and blood vials.) Yes No

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9. Materials to be decontaminated outside of the laboratory are placed in a durable, leak-proof container and closed for transport from the laboratory. Yes No

B. Special Practices

1. Persons who are at an increased risk of acquiring infection or for whom infection may be unusually hazardous (e.g., immunocompromised, immunosuppressed, pregnant) are not allowed to enter the laboratory when BSL-2 work is in progress. Yes No

2. The laboratory supervisor has developed an annually reviewed and updated BSL-2 Biosafety manual that is posted in the lab. Yes No

3. There is documentation that students are trained and made aware of hazards and appropriate precautions before working in the laboratory. Yes No

4. There are established policies and procedures which limit entrance to the lab to individuals who are advised of the potential hazards and are appropriately trained. Yes No

5. There is a hazard warning sign (e.g., biohazard warning symbol) posted on the access door to the laboratory. The sign should identify the Biosafety level, the name and the telephone number of the laboratory supervisor or other responsible person(s), special requirements and items prohibited, and personal protective equipment required for entry. Yes No

6. A biohazard symbol is placed on equipment (e.g., incubators, freezers) where biohazardous materials are used or stored. Yes No

7. Spills and accidents are immediately reported to the laboratory supervisor and an incident report submitted. Yes No

C. Safety Equipment (Primary Barriers)

1. Protective laboratory coats are worn while in the laboratory and then removed and left in the laboratory after use. These coats are never taken home for laundering. They are either disposed of or laundered by the school. Yes No

2. When required, suitable gloves (e.g., latex, nitrile, vinyl) are worn and appropriately disposed of after use. Yes No

D. Laboratory Equipment (Secondary Barriers)

1. The laboratory has a sink for hand washing. Yes No

2. The laboratory is designed so that it can be easily cleaned and decontaminated. (Carpets and rugs are not appropriate) Yes No

3. Bench tops are impervious to water and resistant to moderate heat, acids, alkalis, organic solvents and chemicals used to decontaminate the work surface. Yes No 8-13 Updated April 2017

4. The laboratory furniture is sturdy and capable of supporting anticipated loads and uses. Yes No

5. The spaces between benches, cabinets, and equipment are accessible for cleaning. Yes No

6. Storage space is adequate to hold supplies for immediate use and thus prevent clutter on bench tops and in aisles. Yes No

7. Long-term storage space is available outside of the laboratory. Yes No

8. Vacuum lines, if present, are protected with liquid disinfectant traps, or HEPA or hydrophobic filters. Yes No

9. If the laboratory has windows that are open, they are fitted with fly screens. Yes No

10. The laboratory doors are kept closed whenever work with biohazardous materials is conducted. Yes No

11. The laboratory is locked when not in use. Yes No

12. An autoclave is available. Yes No

13. An eyewash facility is readily available within the laboratory. Yes No

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Part 9a. Biomedical Waste Operating Plan - Georgia

FACILITY NAME: Philadelphia College of Osteopathic Medicine - Georgia Campus

TABLE OF CONTENTS

I. PURPOSE

II. TRAINING FOR PERSONNEL

III. DEFINITION, IDENTIFICATION, AND SEGREGATION OF BIOMEDICAL WASTE

IV. CONTAINMENT

V. LABELING

VI. STORAGE

VII. TRANSPORT

VIII. PROCEDURE FOR DECONTAMINATING BIOMEDICAL WASTE SPILLS

IX. CONTINGENCY PLAN

X. BRANCH OFFICES

XI. MISCELLANEOUS

ATTACHMENT A: BIOMEDICAL WASTE TRAINING OUTLINE

ATTACHMENT B: BIOMEDICAL WASTE TRAINING ATTENDANCE

ATTACHMENT C: PLAN FOR TREATMENT OF BIOMEDICAL WASTE

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I. PURPOSE The purpose of this Biomedical Waste Operating Plan is to provide guidance and describe requirements for the proper management of biomedical waste in our facility. Guidelines for management of biomedical waste are found in Chapter 391-3-4-.15 in the Rules and Regulations of the State of Georgia which are also included in this handbook.

II. TRAINING FOR PERSONNEL Biomedical waste training will be scheduled as required by the Rules and Regulations of the State of Georgia. Training sessions will detail compliance with this operating plan and with Chapter 391-3-4-.15. Training sessions will include all of the following activities that are carried out in our facility: . Definition and Identification of Biomedical Waste . Segregation . Storage . Labeling . Transport . Procedure for Decontaminating Biomedical Waste Spills . Contingency Plan for Emergency Transport . Procedure for Containment . Treatment Method Training for the activities that are carried out in our facility is outlined in Attachment A.

Our facility must maintain records of employee training. These records will be kept in the lab technician’s office. Training records will be kept for participants in all training sessions for a minimum of three (3) years and will be available for review by Department of Health (DOH) inspectors. An example of an attendance record is appended in Attachment B.

III. DEFINITION, IDENTIFICATION, AND SEGREGATION OF BIOMEDICAL WASTE Biomedical waste is any solid or liquid waste which may present a threat of infection to humans.

Items of sharps and non-sharps biomedical waste generated in this facility and the locations at which they are generated are:

. Small single use experimental needles (Lab Spaces 1, 2, 3 and SOP) . Cell culture waste (Lab 1, 2 and SOP) . Bacteria cell culture growth and plates (Lab 3 and SOP) . Small amounts of human tissues (Anatomy) . Soiled gloves and hand towels (Anatomy) . Strong acids and bases (Lab Hood space)

If biomedical waste is in a liquid or semi-solid form and aerosol formation is minimal, the waste may be disposed into a sanitary sewer system or into another system approved to receive such waste by the Department of Environmental Protection or the DOH.

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IV. CONTAINMENT Red bags for containment of biomedical waste will comply with the required physical properties. Our red bags are manufactured by • Maxxim Medical Our documentation of red bag construction standards is kept • Pass ASTMD1709-85, 165 Gram Dart Test Working staff can quickly get red bags at • All unused red bags are kept in the shared hallway by the autoclave in the bottom drawer Sharps will be placed into sharps containers at the point of origin. All animal carcasses and tissues will be stored in the freezer for current experiments. Filled red bags and filled sharps containers will be sealed at the point of origin. Red bags, sharps containers, and outer containers of biomedical waste, when sealed, will not be reopened in this facility. Ruptured or leaking packages of biomedical waste will be placed into a larger container without disturbing the original seal.

V. LABELING All sealed biomedical waste red bags and sharps containers will be labeled with this facility’s name and address prior to offsite transport. If a sealed red bag or sharps container is placed into a larger red bag prior to transport, placing the facility’s name and address only on the exterior bag is sufficient. Outer containers must be labeled with our transporter’s name, address, registration number, and 24-hour phone number.

VI. STORAGE When sealed, red bags, sharps containers, and outer containers will be stored in areas that are restricted through the use of locks, signs, or location. The 30-day storage time period will commence when the first non-sharps item of biomedical waste is placed into a red bag or sharps container, or when a sharps container that contains only sharps is sealed.

Indoor biomedical waste storage areas will be constructed of smooth, easily cleanable materials that are impervious to liquids. These areas will be regularly maintained in a sanitary condition. The storage area will be vermin/insect free. Outdoor storage areas also will be conspicuously marked with a six-inch international biological hazard symbol and will be secure from vandalism. Biomedical waste will be stored and restricted in the following manner: • Biomedical waste is taken care of right away for the lab spaces. All cell culture waste when it becomes full is autoclaved right away then thrown away. All bacteria plate growth when the container becomes full is autoclaved then thrown away. If something is produced that is not autoclaved, such as tissue, then, that material is transferred and placed into an approved biohazardous waste box located within the GA-PCOM Anatomy Lab. The biohazardous boxes are safely stored in a secure area until an approved biohazardous waste provider such as Stericycle and/or MCF Environmental Service, Inc. can respond and properly remove the waste. 9-3 Updated March 2017

VII. TRANSPORT We will negotiate for the transport of biomedical waste only with a DOH-registered company. If we contract with such a company, we will have on file the pick-up receipts provided to us for the last three (3) years. Transport for our facility is provided by:

• The following registered biomedical waste transporter: Stericycle Phone #: 404-362-9090 1924 Joy Lake Road Lake City, GA 30260 Registration #: 8153214 Manifests and/or removal logs maintained by: Jeff Seiple (x7477) and Alisia Curtis (x7560) MCF Environmental Services, Inc. Phone #: 770-593-9434 4319 Tanners Church Road Ellenwood, GA 30294 Registration #: 5112398 Manifests and/or removal logs maintained by: Jeff Seiple (x7477) and Alisia Curtis (x7560)

VIII. PROCEDURE FOR DECONTAMINATING BIOMEDICAL WASTE SPILLS • If a spill happens in the lab space, it is cleaned up with absorbency mats which are non-reactive with soap and water. Then bleach and ethanol are used to disinfect the floor and/or bench top. For anatomy simple spills are decontaminated by anti-bio soaps and water. For bigger spills (formaldehydes), they are neutralized with ammonia and then clean with anti-bio soaps and water. IX. CONTINGENCY PLAN If our registered biomedical waste transporter is unable to transport this facility’s biomedical waste, or if we are unable temporarily to treat our own waste, then the following registered biomedical waste transporter will be contacted:

To be placed in a locked room till pick up can be arranged. Signs in the normal pick up area would be placed to make sure that when pick up was continued the locked room would be checked.

X. BRANCH OFFICES The personnel at our facility work at the following branch offices during the days and times indicated:

1) Office name: N/A

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Office address: N/A Days of operation: N/A Hours of operation: N/A

XI. MISCELLANEOUS For easy access by all of our staff, a copy of this biomedical waste operating plan will be kept in the following place: • This biomedical waste operating plan will be kept in the safety manual in the Basic Science lab space.

The following items will be kept where indicated:

a. Current DOH biomedical waste permit/ exemption document #8153214 b. Current copy of Chapter 391-3-4.15 . Is located in this book following this report. c. Copies of biomedical waste inspection reports from last three (3) years . None at this time d. Transport log . N/A

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ATTACHMENT A: BIOMEDICAL WASTE TRAINING OUTLINE

Facility Name: Philadelphia College of Osteopathic Medicine - Georgia Campus

Trainer’s Name: Yan Wu

Outline:

Review the rules on disposal and proper locations of disposal of bio-hazardous waste Review the proper safety training on how to dispose of items Review the proper use of the autoclave and sharp containers Review spill cleanup (Chemicals, blood, etc.)

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Part 10. PCOM Automated External Defibrillator Program

The Philadelphia College of Osteopathic Medicine (PCOM) provides Automated External Defibrillators (AEDs) to make early defibrillation available to persons who experience sudden cardiac arrest at the following locations:

PCOM - Philadelphia, PA campus

PCOM Health Care Centers – Philadelphia, PA

PCOM - Suwanee, GA campus

Sullivan County Medical Center – LaPorte, PA

AEDs are intended for use by the general public. They will be located where they are readily available. AED wall mounts will be alarmed so that personnel in the vicinity of the AED will be notified whenever an AED is removed from its case. The AEDs will be located near telephones so that the responder can contact EMS.

See Appendix A for AED locations.

Philadelphia

Each use of an AED at PCOM shall be accompanied by a call to the PCOM Security Dispatcher at 6911 from Philadelphia PCOM locations. Give the security dispatcher the building and suite number, and details of the illness. The security dispatcher will immediately contact 9-1-1 and give the 9-1-1 operator the PCOM address, building, suite number, and details of the illness. The security dispatcher will designate someone available to meet and direct the EMS personnel upon their arrival.

Georgia

Each use of an AED at PCOM shall be accompanied by a call to the PCOM Security Dispatcher at 2911 from Georgia PCOM locations. Give the security dispatcher the building, suite number, and details of the illness. The security dispatcher will immediately contact 9-1-1 and give the 9-1-1 operator the PCOM address, building and suite number, and details of the illness. The security dispatcher will designate someone available to meet and direct the EMS personnel upon their arrival.

Refer to the instructions on the AED Quick Reference Card. Upon arrival of EMS personnel, relay the history of the incident. Patient jurisdiction will then be turned over to EMS personnel.

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LaPorte

Each use of an AED at shall be accompanied by a call to 9-1-1 from the LaPorte PCOM location. Give the 9-1-1 operator the address, suite number, and details of the illness. Someone will be designated to meet and direct the EMS personnel upon their arrival.

Refer to the instructions on the AED Quick Reference Card. Upon arrival of EMS personnel, relay the history of the incident. Patient jurisdiction will then be turned over to EMS personnel.

See Appendix B for a copy of the AED Quick Reference Card.

The PCOM Security Department will maintain weekly and monthly maintenance checklists for each AED, which will indicate their functional status.

See Appendix C and Appendix D for sample formats.

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APPENDICES INDEX:

Appendix A: AED Locations

Appendix B: AED Quick Reference Card

Appendix C: Sample AED Weekly Maintenance Log

Appendix D: Sample AED Monthly Maintenance Log

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Appendix A:

Philadelphia AED Locations

ID # 1: Rowland Hall; 4190 City Avenue; Philadelphia, PA 19131 Location: Main Lobby security desk

ID #2: Activity Center; 4190 City Avenue; Philadelphia, PA 19131 Location: Main Lobby across from security desk

ID # 3: Evans Hall; 4170 City Avenue; Philadelphia, PA 19131 Location: Main Lobby by Admissions (Room 120 Evans Hall)

ID #4: Levin Administration Building; 4180 City Avenue; Philadelphia, PA 19131 Location: First floor elevator hallway (through Chairman of the Board’s Office)

ID #5: Spare; 4190 City Avenue, Suite 232, Philadelphia, PA 19131 Location: Office of Director of Security and Public Safety

ID #6: Cambria HCC; 2100 W. Cambria Street; Philadelphia, PA 19132 Location: security desk

ID #7: Lancaster Division HCC; 4148 Lancaster Avenue; Philadelphia, PA 19104 Location: security desk

LaPorte AED Location

ID #8: Sullivan County Medical Center; Main and King Streets; Laporte, PA 18626 Location: on the counter behind the doctors’ center desk

Georgia AED Locations

ID #9: Location (1): front entrance; wall-mounted opposite the security desk

ID #10: Location (2): rear entrance; wall-mounted near Lactation / Meditation Rooms 4003 & 4004

ID #11: Location (3): 2601 Building; security desk

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Appendix B: AED Quick Reference Card for Philips FRx AED

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Appendix C: Sample AED Weekly Maintenance Log

Year: 20___ AED Weekly Maintenance Log Serial #: ______

(Complete a separate record for each AED)

Month Week 1 Week 2 Week 3 Week 4 Week 5

Date &  Date &  Date &  Date &  Date &  Initial Initial Initial Initial Initial Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

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Appendix D: AED Monthly Maintenance Log

Year: 20___ AED Monthly Maintenance Log Serial #: ______

(Complete a separate record for each AED)

Month Spare Spare Other Date Initials Comments Battery Pads accessories Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

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Part 11. PCOM Exposure Control Plan

Philadelphia College of Osteopathic Medicine Occupational and Environmental Safety Department

Developed by: Philadelphia College of Osteopathic Medicine Occupational & Environmental Safety Department

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POLICY

The Philadelphia College of Osteopathic Medicine (PCOM) is committed to providing a safe and healthful work environment for our entire staff. In pursuit of this goal, the following exposure control plan (ECP) is provided to eliminate or minimize occupational exposure to bloodborne pathogens in accordance with the Occupational Safety and Health Administration (OSHA) standard 29 CFR 1910.1030, "Occupational Exposure to Bloodborne Pathogens." Universal precautions will be utilized to prevent contact with blood or other potentially infectious materials. Under circumstances in which differentiation between body fluid types is difficult or impossible, all body fluids shall be considered potentially infectious materials.

The ECP is a key document to assist our organization in implementing and ensuring compliance with the standard, thereby protecting our employees. This ECP will be reviewed and updated at least annually and whenever necessary to reflect new or modified tasks and procedures which affect occupational exposure and to reflect new or revised employee positions with occupation exposure. This ECP includes: • Determination of employee exposure • Implementation of various methods of exposure control, including: o Universal precautions o Engineering and work practice controls o Personal protective equipment o Housekeeping • Hepatitis B vaccination • Post-exposure evaluation and follow-up • Communication of hazards to employees and training • Recordkeeping • Procedures for evaluating circumstances surrounding exposure incidents Implementation methods for these elements of the standard are discussed in the subsequent pages of this ECP.

PROGRAM ADMINISTRATION

PCOM’s Occupational & Environmental Safety Department is responsible for implementation of the ECP. The Occupational & Environmental Safety Department will maintain, review, and update the ECP at least annually, and whenever necessary to include new or modified tasks and procedures. The Occupational & Environmental Safety Department is located in Rowland Hall, Suite 307; Phone (215) 871-6360.

Those employees who are determined to have occupational exposure to blood or other potentially infectious materials (OPIM) must comply with the procedures and work practices outlined in this ECP.

The Occupational & Environmental Safety Department will confirm availability and

11-2 Updated March 2017 maintenance of all necessary personal protective equipment (PPE), engineering controls (e.g., sharps containers), labels, and red bags as required by the standard. The Occupational & Environmental Safety Department will ensure that adequate supplies of the aforementioned equipment are available in the appropriate sizes.

The Occupational & Environmental Safety Department will be responsible for ensuring that all medical actions required by the standard are performed and that appropriate employee health and OSHA records are maintained.

The Occupational & Environmental Safety Department will be responsible for training, documentation of training, and making the written ECP available to employees, OSHA, and National Institute for Occupational Safety and Health (NIOSH) representatives.

EMPLOYEE EXPOSURE DETERMINATION

The following is a list of all job classifications at our facility in which all employees have occupational exposure:

Health Care Workers: Responds to illnesses, accidents and injuries that involve exposure to human blood or other body fluids. Laboratory Animal Resources (LAR) Personnel: Works closely with animals and may be exposed to animal blood or other body fluids. Principal Investigators, Professors, Associate Professors, Assistant Professors, and Research Assistants: Conducts research that involves the use of human blood, unfixed tissue, or cell lines and handles laboratory instruments, utensils, etc. that may be contaminated with infectious materials. Workstudy Students: May work closely with employees (faculty and staff) who work closely with human blood, body fluids or animals. Maintenance Staff: Repairs and maintains facilities, equipment, and fixtures that may contain infectious materials. Security Staff: Responds to situations that may involve exposure to human blood or other body fluids. Activities Center Staff: Responds to situations that may involve exposure to human blood or other body fluids.

DEFINITIONS

Bloodborne Pathogens: Pathogenic microorganisms that are present in human blood and can cause disease in humans. These disease causing organisms can be found in all body fluids, unfixed tissue, cell lines and in situations where it is difficult or impossible to differentiate between body fluids and other materials.

Contamination: The presence of blood or other potentially infectious materials on an item or 11-3 Updated March 2017 surface.

Contaminated Sharps: Any contaminated object that can penetrate the skin including, but not limited to, needles, scalpels, broken glass, broken capillary tubes, and exposed ends of dental wires.

Decontamination: The use of physical or chemical means to remove, inactivate, or destroy bloodborne pathogens on a surface or item to the point where they are no longer capable of transmitting infectious particles and the surface or item is rendered safe for handling, use or disposal. Engineering Controls: Controls (e.g., sharps disposal containers, self-sheathing needles) that isolate or remove the bloodborne pathogens hazard from the workplace.

Exposure Incident: A specific eye, mouth, other mucous membrane, non-intact skin, or parenteral contact with blood or other potentially infectious materials that results from the performance of an employee's duties.

HBC: Hepatitis C Virus.

HBV: Hepatitis B Virus.

HIV: Human Immunodeficiency Virus.

Occupational Exposure: Reasonably anticipated skin, eye, mucous membrane, or parenteral contact with blood or other potentially infectious materials that may result from the performance of an employee's duties.

Parenteral: Piercing mucous membranes or the skin barrier through such events as needle sticks, human bites, cuts, and abrasions.

Personal Protective Equipment (PPE): is specialized clothing or equipment worn by an employee for protection against a hazard. General work clothing (e.g., uniforms, pants, shirts, or blouses) not intended to function as protection against a hazard is not considered to be personal protective equipment.

Regulated Waste: Liquid or semi-liquid blood or other potentially infectious materials; contaminated items that would release blood or other potentially infectious materials in a liquid or semi-liquid state if compressed; items that are caked with dried blood or other potentially infectious materials and are capable of releasing these materials during handling; contaminated sharps; and pathological and microbiological wastes containing blood or other potentially infectious materials.

Source Individual: Any individual, living or dead, whose blood or other potentially infectious materials may be a source of occupational exposure to the employee.

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Universal Precautions: Is an approach to infection control. According to the concept of Universal Precautions, all human blood and certain human body fluids are treated as if known to be infectious for HIV, HBV, and other bloodborne pathogens.

Work Practice Controls: Controls that reduce the likelihood of exposure by altering the manner in which a task is performed (e.g., prohibiting recapping of needles by a two-handed technique).

METHODS OF IMPLEMENTATION AND CONTROL

Universal Precautions All employees will utilize universal precautions.

Exposure Control Plan Employees covered by the bloodborne pathogens standard receive an explanation of this ECP during their initial training session. It will also be reviewed in their annual refresher training. All employees can review this plan at any time during their work shifts by contacting the Occupational & Environmental Safety Department or by contacting the responsible person at each PCOM facility. If requested, we will provide an employee with a copy of the ECP free of charge and within 15 days of the request.

The Occupational & Environmental Safety Department is responsible for reviewing and updating the ECP annually or more frequently if necessary to reflect any new or modified tasks and procedures that affect occupational exposure and to reflect new or revised employee positions with occupational exposure.

Engineering Controls and Work Practices Engineering controls and work practice controls will be used to eliminate or minimize employee exposure to bloodborne pathogens. The specific engineering controls and work practice controls used are listed below:

• Sharps disposal containers are inspected and maintained or replaced by the responsible person in the facility whenever necessary to prevent overfilling.

• PCOM will provide readily accessible hand washing sinks for employees use. Employees will be trained to wash their hands with soap and running water as soon as possible after any exposure and after removing personal protective equipment (PPE). When hand washing sinks are not possible, appropriate antiseptic hand cleanser will be provided.

• This facility identifies the need for changes in engineering controls and work practices through review of OSHA records, employee interviews, committee activities, etc.

• Eating, drinking, smoking, applying cosmetics or lip balm, and handling contact lenses are prohibited in work areas where there is a reasonable likelihood of occupational exposure. Food and drink will not be kept in refrigerators, freezers, shelves, cabinets or

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on countertops or bench tops where blood or other potentially infectious materials are present.

• We evaluate new procedures and new products regularly by periodically reviewing literature and supplier info. ______.

Both front-line workers and management officials are involved in this process.

The Occupational & Environmental Safety Department is responsible for ensuring that these recommendations are implemented.

PPE is provided to our employees at no cost to them. Training in the use of the appropriate PPE for specific tasks or procedures is provided by The Occupational & Environmental Safety Department.

The types of PPE available to employees are as follows:

• Gloves will be worn when there is potential for hand contact with blood or other potentially infectious materials and when handling or touching contaminated items or surfaces. Hypoallergenic gloves, glove liners, powderless gloves or other similar alternatives will be readily accessible to those employees who are allergic to the gloves normally provided.

• Face shields and marks in combination with eye protection devices, such as goggles or safety glasses with solid side shields will be worn whenever splashes, spray, spatter, or droplets of blood or other potentially infectious materials may be generated.

• Gowns, aprons, lab coats, clinic jackets or similar outer garments will be worn in occupational exposure situations. Surgical caps or hoods and/or shoe covers or boots will be worn in instances when gross contamination can reasonable by anticipated.

• PPE locations, which vary by facility, may be obtained from the PCOM Occupational & Environmental Safety Department. The PI for each research project is responsible for ensuring that PPE is available.

All employees using PPE must observe the following precautions: • Wash hands immediately or as soon as feasible after removing gloves or other PPE.

• Remove PPE after it becomes contaminated and before leaving the work area.

• Used PPE may be disposed of in biohazard waste containers.

• Wear appropriate gloves when it is reasonably anticipated that there may be hand 11-6 Updated March 2017

contact with blood or OPIM, and when handling or touching contaminated items or surfaces; replace gloves if torn, punctured or contaminated, or if their ability to function as a barrier is compromised.

• Utility gloves may be decontaminated for reuse if their integrity is not compromised; discard utility gloves if they show signs of cracking, peeling, tearing, puncturing, or deterioration.

• Never wash or decontaminate disposable gloves for reuse.

• Wear appropriate face and eye protection when splashes, sprays, spatters, or droplets of blood or OPIM pose a hazard to the eye, nose, or mouth.

• Remove immediately or as soon as feasible any garment contaminated by blood or OPIM, in such a way as to avoid contact with the outer surface.

Housekeeping Regulated waste is placed in containers which are closable, constructed to contain all contents and prevent leakage, appropriately labeled or color-coded, and closed prior to removal to prevent spillage or protrusion of contents during handling.

Contaminated needles and sharps are discarded immediately (or as soon as possible) in containers that are closable, puncture-resistant, leak proof on sides and bottoms, and appropriately labeled or color-coded. Sharps disposal containers must be easily accessible and as close as feasible to the immediate area where sharps are used. Contaminated needles and sharps will not be bent, recapped, or removed unless no alternative is feasible or that such action is required by a specific medical or dental procedure. Such bending, recapping, or needle removal must be accomplished through the use of a mechanical device.

DO NOT PICK UP NEEDLES WITH YOUR HANDS NEEDLES SHALL BE MOVED OR PICKED UP ONLY BY USING A MECHANICAL DEVICE OR TOOL (FORCEPS, PLIERS, BROOM AND DUST PAN)

Reusable sharps that are contaminated with blood or other potentially infectious materials will not be stored or processed in a way where employees will have to reach by hand into the containers where the sharps are.

All procedures involving blood or other potentially infectious materials will be performed in such a manner as to minimize splashing, spraying, spattering, and generation of droplets of these substances. Mouth pipetting/suctioning of blood or other potentially infectious materials is prohibited.

Specimens of blood or other potentially infectious materials will be placed in a container which prevents leakage during collection, handling, processing, storage, transport, or shipping. Containers used for storage, transport or shipping will be biohazard labeled and closed prior to

11-7 Updated March 2017 being stored, transported or shipped.

Containers, bins and pails (e.g., wash or emesis basins) are cleaned and decontaminated as soon as feasible after visible contamination.

Protective coverings, such as plastic wrap, aluminum foil, or imperviously-backed absorbent paper used to cover equipment and environmental surfaces will be removed and replaced when contaminated.

Broken glassware that may be contaminated is only picked up using mechanical means, such as a brush and dustpan.

The Occupational & Environmental Safety Department is responsible for ensuring that warning labels are affixed or red bags are used as required if regulated waste or contaminated equipment is brought into the facility. Employees are to notify the Occupational & Environmental Safety Department if they discover regulated waste containers, refrigerators containing blood or OPIM, contaminated equipment, etc., without proper labels.

HEPATITIS B VACCINATION

The Occupational & Environmental Safety Department will provide training to employees on hepatitis B vaccinations, addressing safety, benefits, efficacy, methods of administration, and availability.

The hepatitis B vaccination series is available at no cost after initial employee training and within 10 days of initial assignment to all employees identified in the exposure determination section of this plan. Vaccination is encouraged unless: 1) documentation exists that the employee has previously received the series; 2) antibody testing reveals that the employee is immune; or 3) medical evaluation shows that vaccination is contraindicated.

However, if an employee declines the vaccination, the employee must sign a declination form. Employees who decline may request and obtain the vaccination at a later date at no cost. Documentation of refusal of the vaccination is kept at The PCOM Occupational & Environmental Safety Department.

Following the medical evaluation, a copy of the health care professional's written opinion will be obtained and provided to the employee within 15 days of the completion of the evaluation. It will be limited to whether the employee requires the hepatitis vaccine and whether the vaccine was administered.

POST-EXPOSURE EVALUATION AND FOLLOW-UP

Should an exposure incident occur, contact the Occupational & Environmental Safety 11-8 Updated March 2017

Department at the following number (215) 871-6360.

An immediately available confidential medical evaluation and follow-up will be conducted by a licensed health care professional). Following initial first aid (clean the wound, flush eyes or other mucous membrane, etc.), the following activities will be performed: • Document the routes of exposure and how the exposure occurred. • Identify and document the source individual (unless the employer can establish that identification is infeasible or prohibited by state or local law). • Obtain consent and make arrangements to have the source individual tested as soon as possible to determine HIV, HCV, and HBV infectivity; document that the source individual's test results were conveyed to the employee's health care provider. • If the source individual is already known to be HIV, HCV and/or HBV positive, new testing need not be performed. • Assure that the exposed employee is provided with the source individual's test results and with information about applicable disclosure laws and regulations concerning the identity and infectious status of the source individual (e.g., laws protecting confidentiality). • After obtaining consent, collect exposed employee's blood as soon as feasible after exposure incident, and test blood for HBV and HIV serological status • If the employee does not give consent for HIV serological testing during collection of blood for baseline testing, preserve the baseline blood sample for at least 90 days; if the exposed employee elects to have the baseline sample tested during this waiting period, perform testing as soon as feasible.

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ADMINISTRATION OF POST-EXPOSURE EVALUATION AND FOLLOW-UP

The Occupational & Environmental Safety Department ensures that health care professional(s) responsible for employee's hepatitis B vaccination and post-exposure evaluation and follow-up are given a copy of OSHA's bloodborne pathogens standard.

The Occupational & Environmental Safety Department ensures that the health care professional evaluating an employee after an exposure incident receives the following:

• a description of the employee's job duties relevant to the exposure incident route(s) of exposure • circumstances of exposure • if possible, results of the source individual's blood test • relevant employee medical records, including vaccination status

The Occupational & Environmental Safety Department provides the employee with a copy of the evaluating health care professional's written opinion within 15 days after completion of the evaluation.

PROCEDURES FOR EVALUATING THE CIRCUMSTANCES SURROUNDING AN EXPOSURE INCIDENT

The Occupational & Environmental Safety Department will review the circumstances of all exposure incidents to determine: • engineering controls in use at the time • work practices followed • a description of the device being used (including type and brand) • protective equipment or clothing that was used at the time of the exposure incident (gloves, eye shields, etc.) • location of the incident (O.R., E.R., patient room, etc.) • procedure being performed when the incident occurred • employee's training

The Occupational & Environmental Safety Department will record all percutaneous injuries from contaminated sharps in a Sharps Injury Log.

If revisions to this ECP are necessary, The Occupational & Environmental Safety Department will ensure that appropriate changes are made. (Changes may include an evaluation of safer devices, adding employees to the exposure determination list, etc.)

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EMPLOYEE TRAINING

All employees who have occupational exposure to bloodborne pathogens receive initial and annual training conducted by The Occupational & Environmental Safety Department.

All employees who have occupational exposure to bloodborne pathogens receive training on the epidemiology, symptoms, and transmission of bloodborne pathogen diseases. In addition, the training program covers, at a minimum, the following elements: • a copy and explanation of the OSHA bloodborne pathogen standard • an explanation of our ECP and how to obtain a copy • an explanation of methods to recognize tasks and other activities that may involve exposure to blood and OPIM, including what constitutes an exposure incident • an explanation of the use and limitations of engineering controls, work practices, and PPE • an explanation of the types, uses, location, removal, handling, decontamination, and disposal of PPE • an explanation of the basis for PPE selection • information on the hepatitis B vaccine, including information on its efficacy, safety, method of administration, the benefits of being vaccinated, and that the vaccine will be offered free of charge • information on the appropriate actions to take and persons to contact in an emergency involving blood or OPIM • an explanation of the procedure to follow if an exposure incident occurs, including the method of reporting the incident and the medical follow-up that will be made available • information on the post-exposure evaluation and follow-up that the employer is required to provide for the employee following an exposure incident • an explanation of the signs and labels and/or color coding required by the standard and used at this facility • an opportunity for interactive questions and answers with the person conducting the training session.

RECORDKEEPING

Training Records are completed for each employee upon completion of training. These documents will be kept for at least three years at The PCOM Occupational & Environmental Safety Department.

• The training records include: • the dates of the training sessions • the contents or a summary of the training sessions • the names and qualifications of persons conducting the training • the names and job titles of all persons attending the training sessions

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• Employee training records are provided upon request to the employee or the employee's authorized representative within 15 working days. Such requests should be addressed to the Occupational & Environmental Safety Department. • Medical Records

Medical records are maintained for each employee with occupational exposure in accordance with 29 CFR 1910.1020, "Access to Employee Exposure and Medical Records."

The Occupational & Environmental Safety Department is responsible for maintenance of the required medical records. These confidential records are kept in a secure location for at least the duration of employment plus 30 years.

Employee medical records are provided upon request of the employee or to anyone having written consent of the employee within 15 working days. Such requests should be sent to The Occupational & Environmental Safety Department.

OSHA Recordkeeping

An exposure incident is evaluated to determine if the case meets OSHA's Recordkeeping Requirements (29 CFR 1904). This determination and the recording activities are done by The Occupational & Environmental Safety Department.

Sharps Injury Log In addition to the 1904 Recordkeeping Requirements, all percutaneous injuries from contaminated sharps are also recorded in a Sharps Injury Log. All incidences must include at least: • date of the injury • type and brand of the device involved (syringe, suture needle) • department or work area where the incident occurred • explanation of how the incident occurred.

This log is reviewed as part of the annual program evaluation and maintained for at least five years following the end of the calendar year covered. If a copy is requested by anyone, it must have any personal identifiers removed from the report.

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HEPATITIS B VACCINE DECLINATION (MANDATORY)

I understand that due to my occupational exposure to blood or other potentially infectious materials I may be at risk of acquiring hepatitis B virus (HBV) infection. I have been given the opportunity to be vaccinated with hepatitis B vaccine, at no charge to myself. However, I decline hepatitis B vaccination at this time. I understand that by declining this vaccine, I continue to be at risk of acquiring hepatitis B, a serious disease. If in the future I continue to have occupational exposure to blood or other potentially infectious materials and I want to be vaccinated with hepatitis B vaccine, I can receive the vaccination series at no charge to me.

Signed: (Employee Name) ______Date: ______

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Appendix A

Maintenance Rule 170 Maintain respirators in a clean and reliable condition Important:

This section applies to employees who voluntarily use respirators only when maintenance is necessary to prevent the respirator from creating a hazard.

(1) Make sure respirators are kept, at no cost to the employee, clean, sanitary and in good working order.

(2) Clean and disinfect respirators as often as specified in Table 8 of this section.

Note: Use required cleaning and disinfecting procedures or the manufacturer’s procedures that: – Result in a clean and sanitary respirator; – Don’t damage the respirator; – Don’t harm the user. Automated cleaning and disinfecting are permitted. Cleaning and disinfecting may be done by a central facility as long as you make sure respirators provided are clean, sanitary, and function properly.

(3) Make sure respirators are assembled properly after cleaning or disinfecting.

Store respirators properly

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(1) Store respirators to protect them from all of the following: (a) Deformation of the face piece or exhalation valve (b) Sunlight or extreme temperatures or other conditions (c) Contamination such as dust or damaging chemicals (d) Excessive moisture.

Note: Use coffee cans, sealable plastic bags, or other suitable means of protection.

(2) Follow these additional requirements for emergency respirators: (a) Keep respirators accessible to the work area (b) Store respirators in compartments or with covers clearly marked as containing emergency respirators (c) Follow additional storage instructions from the respirator manufacturer (d) Store an adequate number of emergency respirators in each area where they may be needed.

Note: Emergency respirators include mouthpiece respirators and other respirators that are limited to escape-only use by their NIOSH certification.

Inspect and repair respirators

(1) Conduct respirator inspections as often as specified in Table 9.

(2) Make sure respirator inspections cover all of the following: (a) Respirator function (b) Tightness of connections (c) The condition of the face piece, head straps, valves, connecting tubes, and cartridge, canisters or filters (d) Pliability and deterioration of elastomeric parts (e) Maintenance of air or oxygen cylinders (f) Making sure SCBA air cylinders are at 90% of the manufacturer’s recommended pressure level (g) Proper functioning of SCBA regulators when air-flow is activated (h) Proper functioning of SCBA low-pressure warning devices when activated

(3) Certify inspections for emergency respirators by documenting the following: (a) Inspection date (b) Serial number of each respirator or other identifying information (c) Inspector’s name or signature (d) Inspection findings (e) Required action, if problems are found.

Note: When documenting inspections you may either: – Provide the information on a tag or label and attach it to the respirator compartment or 11-15 Updated March 2017

– Include the information in an inspection report stored in paper or electronic files accessible to employees.

(4) Repair or replace any respirator that isn’t functioning properly before the employee returns to a situation where respirators are required. If respirators fail inspection or aren’t functioning properly during use due to problems such as leakage, vapor or gas breakthrough, or increased breathing resistance all of the following apply:

(a) Do not permit such respirators to be used until properly repaired or adjusted (b) Use only NIOSH-certified parts (c) Make sure repairs and adjustments are made by appropriately trained individuals. Use the manufacturer or a technician trained by the manufacturer to repair or adjust reducing and admission valves, regulators, and warning devices on SCBAs or air-line respirators. (d) Follow the manufacturer’s recommendations and specifications for the type and extent of repairs.

(5) Use Table 9 to determine how often to inspect respirators.

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Please contact for further assistance: Nate Pinkney Chief Occupational/Environmental Safety Officer Office 215-871-6360 | fax 215-871-6359

Pamela Vu, MPH Occupational Safety Specialist Office 215-871-6150 | fax 215-871-6359

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Part 12. PCOM Hazard Communication Program

Philadelphia College of Osteopathic Medicine Occupational and Environmental Safety Department

POLICY

To ensure that information about the dangers of all hazardous chemicals used by the Philadelphia College of Osteopathic Medicine (PCOM) is known by all affected employees, the following hazardous information program has been established. Under this program, you will be informed of the contents of the OSHA Hazard Communication Standard (HCS), the hazardous properties of chemicals with which you work, safe handling procedures and measures to take to protect yourself from these chemicals. In order to ensure chemical safety in the workplace, information about the identities and hazards of the chemicals must be available and understandable to workers. OSHA’s HCS requires the development of the following information:

• Chemical manufacturers and importers are required to evaluate the hazards of the chemicals they produce or import, and prepare labels and safety data sheets (SDSs) to convey the hazard information to their downstream customers. • All employers with hazardous chemicals in their workplaces must have labels and SDSs for their exposed workers and train them to handle the chemicals appropriately.

The HCS is now aligned with the Globally Harmonized System of Classification and Labeling of Chemicals (GHS). This update to the HCS will deliver a common approach to classifying chemicals and communicating hazard information on labels and SDSs.

This program applies to all work operations in a PCOM facility where you may be exposed to hazardous chemicals under normal working conditions or during an emergency situation. All work units of this facility will participate in the Hazard Communication Program. Copies of the Hazard Communication Program are available in the (location) for review by any interested employee.

The PCOM Occupational/Environmental Safety Officer is the program coordinator, with overall responsibility for the program, including reviewing and updating this plan as necessary.

CONTAINER LABELING

The Occupational & Environmental Safety Department will verify that all containers received for use will be clearly labeled as to the contents, initial preparer, date of preparation, note the appropriate hazard warning, and list the manufacturer's name and address. 12-1 Updated March 2017

The Occupational & Environmental Safety Department shall appoint a responsible person in each section, who will ensure that all secondary containers are labeled with either an extra copy of the original manufacturer's label or with labels marked with the identity and the appropriate hazard warning. For help with labeling, contact the Occupational & Environmental Safety Department.

The Occupational & Environmental Safety Department will review PCOM’s labeling procedures annually and will update labels as required.

SAFETY DATA SHEETS (SDSs)

The Occupational & Environmental Safety Department is responsible for establishing and monitoring PCOM’s SDS program. He/she will ensure that procedures are developed to obtain the necessary SDSs and will review incoming SDSs for new or significant health and safety information. He/she will see that any new information is communicated to affected employees. SDSs will now have a specified 16-section format.

Copies of SDSs for all hazardous chemicals to which employees are exposed or are potentially exposed will be maintained. Each department may maintain their own SDS in a central location within the department.

SDSs will be readily available to all employees during each work shift. If an SDS is not available, contact the Occupational & Environmental Safety Department.

SDSs will be readily available to employees in each work area:

Master files of all SDSs will be maintained at the security front desk in Rowland Hall, Plant Operations, 2nd floor, Rowland Hall and in the Occupational & Environmental Safety Department, 2nd floor, Evans Hall.

EMPLOYEE TRAINING AND INFORMATION

The Occupational & Environmental Safety Officer is responsible for the Hazard Communication Program and will ensure that all program elements are carried out.

Everyone who works with or is potentially exposed to hazardous chemicals will receive initial training on the hazard communication standard and this plan before starting work. Each new employee will attend a health and safety orientation that includes the following information and training: • An overview of the OSHA hazard communication standard • The hazardous chemicals present at his/her work area • The physical and health risks of the hazardous chemicals • Symptoms of overexposure 12-2 Updated March 2017

• How to determine the presence or release of hazardous chemicals in the work area • How to reduce or prevent exposure to hazardous chemicals through use of control procedures, work practices, and personal protective equipment (PPE) • Steps PCOM has taken to reduce or prevent exposure to hazardous chemicals • Procedures to follow if employees are overexposed to hazardous chemicals • How to read labels and SDSs to obtain hazard information • Location of the SDS file and written Hazard Communication program

Prior to introducing a new chemical hazard into any section of PCOM, each employee in that section will be given information and training as outlined above for the new chemical hazard. Training formats may include audiovisuals, face-to-face by PI, interactive computer programs, one-on-one, classroom instruction, etc.

HAZARDOUS NON-ROUTINE TASKS

Periodically, employees are required to perform non-routine tasks that are hazardous. Examples of non-routine tasks are: confined space entry, tank cleaning, and painting reactor vessels. Prior to starting work on such projects, each affected employee will be given information by the Occupational & Environmental Safety Department about the hazardous chemicals he or she may encounter during such activity. This information will include specific chemical hazards, protective and safety measures the employee should use, and steps PCOM is taking to reduce the hazards, including ventilation, respirators, the presence of another employee (buddy systems), and emergency procedures.

INFORMING OTHER EMPLOYERS/CONTRACTORS

It is the responsibility of the Occupational & Environmental Safety Department to provide other employers and contractors with information about hazardous chemicals that their employees may be exposed to on a job site and suggested precautions for employees. It is the responsibility of the Occupational & Environmental Safety Department to obtain information about hazardous chemicals used by other employers to which employees of PCOM may be exposed.

Other employers and contractors will be provided with SDSs for hazardous chemicals generated by PCOM's operations.

In addition to providing a copy of an SDS to other employers, other employers will be informed of necessary precautionary measures to protect employees exposed to operations performed by PCOM.

Also, other employers will be informed of the hazard labels used by PCOM. If symbolic or numerical labeling systems are used, the other employees will be provided with information to understand the labels used for hazardous chemicals for which their employees may have exposure. 12-3 Updated March 2017

LIST OF HAZARDOUS CHEMICALS

A list of all known hazardous chemicals used by our employees should be maintained. This list includes the name of the chemical, the manufacturer, the work area in which the chemical is used, dates of use, and quantity used.

When new chemicals are received, this list is updated (including date the chemicals were introduced) within 30 days.

The hazardous chemical inventory is compiled and maintained by the PCOM Occupational & Environmental Safety Department and is available on myPCOM (my.pcom.edu).

PROGRAM AVAILABILITY

A copy of this program will be made available, upon request, to employees and their representatives. Contact the PCOM Occupational & Environmental Safety Department at (215) 871-6360.

CONTACTING OSHA

To report an emergency, file a complaint, or seek OSHA advice, assistance, or products, call (800) 321-OSHA or contact your nearest OSHA regional or area office listed at the end of this publication. The teletypewriter (TTY) number is (877) 889-5627.

You can also file a complaint online and obtain more information on OSHA federal and state programs by visiting OSHA's website at www.osha.gov.

------OSHA Regional Offices

Region III The Curtis Center 170 S. Independence Mall West Suite 740 West Philadelphia, PA 19106-3309 (215) 861-4900

Region IV Atlanta Federal Center 61 Forsyth Street SW, Room 6T50 Atlanta, GA 30303 (404) 562-2300

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Part 13a. Chemical Hygiene Plan - Georgia

Philadelphia College of Osteopathic Medicine Occupational and Environmental Safety Department

Please contact for further assistance:

Nate Pinkney Pamela Vu, MPH Chief Occupational/Environmental Safety Officer Occupational Safety Specialist office 215-871-6360 | fax 215-871-6359 office 215-871-6150 | fax 215-871-6359

Laboratory safety is an integral part of laboratory research and is essential to ensure that Philadelphia College of Osteopathic Medicine’s (PCOM) compliance with all applicable environmental, health and safety laws, regulations and requirements are maintained.

All labs using chemicals are required by OSHA to have a written safety plan (Chemical Hygiene Plan) in place for chemical workers. It is the responsibility of the PCOM Occupational and Environmental Safety Department to confirm that a complete Chemical Hygiene Plan is developed, implemented and shared with all their affected workers. When complete, add these templates to the “CHP” tab of your CHP binder. PCOM is committed to providing a healthy and safe work environment for their employees and students. The CHP describes the proper use and handling procedures to be followed by faculty, staff and students working with hazardous chemicals in the laboratories.

General Laboratory Information

Laboratory Supervisor: Handong Ma (x2775)

Laboratory Location(s) (Building /Rooms): Basic Science, lab space 1, 2 and 3, anatomy lab and School of Pharmacy (SOP) lab

Department Information Chemical Hygiene Officer: Jeff Seiple | Work Number: 678-225-7477 | Work Email: [email protected]

Department Safety Representative: Jeff Seiple, MBA, Vice-Chair (x7477), Xinyu (Eric) Wang, Ph.D., School of Pharmacy (x7365)

Location of Department Safety Bulletin Board: Hallway Bulletin Board immediately outside research labs

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Location of Building Emergency Assembly Points: Parking lots immediately in front of main entrance and parking lot outside back entrance

Georgia Campus: When exiting through any exits, proceed directly to 625 Old Peachtree Road, rear parking lot. When exiting through the main entrance, proceed directly to the left to the new parking lot. When exiting through the rear exits, proceed directly to 2601 Building parking lot. Wait for further instructions.

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Emergency Information

As applicable, please provide information regarding emergency procedures and equipment specific to the lab(s) under your control. Where applicable you may just reference the emergency contact information on your lab door placards.

• Evacuation procedures (e.g., close fire doors, secure certain equipment, etc.) • In case of a fire leave the lab and go straight out of the building.

• First-aid kit (e.g., location, contents, maintenance responsibility, etc.) • The 1st aid kit is located by the front lab door. It contains minor injury supplies. Whenever something is used from here even for minor injuries it should be reported. The first aid kit is checked every 3 months for supplies.

• Spill cleanup materials (e.g., location, contents, maintenance, procedures, etc.) • The spill cleanup kit is located in two locations. The 1st location by the front entrance of the labs’ space to the left of the 1st aid kit. This one contains the necessary supplies for oil or chemical spills. The other spill kit location is in the balance room. This location contains “Pig Mats” for liquid spills. They are super absorbent mats that are non-reactive and are recommended for easier liquid clean up. These both are checked every 3 months. • Each department maintains one or more spill control centers. Chemical spills must be promptly contained and absorbed. Therefore, a spill control center must have such items as universal pillows, disposable aprons, absorbing/neutralizing agents for acids, bases, solvents, and formaldehyde/paraformaldehyde, mercury storage containers, full-face respirator, safety goggles, and gloves. The absorbed material must be scooped up and placed into a plastic bag for regular trash disposal. Hazardous substance spills, regardless of type and amount, must be reported immediately to the PCOM Security Dispatcher. • In the case of a hazardous spill resulting from the usage of an eyewash station or safety shower, clean up spills that may have spilled onto the floor using spill cleanup materials.

• Laboratory monitors or alarms (e.g., operation, response, maintenance, etc.) • Labs 1, 2 and 3 all their incubators and freezers are on alarms. The hallway -85oC freezers are also on an alarm system. The system is a Sensaphone system that is programmed to call the lab technician and the main professor in charge of the lab that has the alarm alert.

Per campus policy, all significant injuries must be documented via the PCOM-GA Report of Injury to Employee/Student form as soon as possible – form available in your departmental office. This is necessary for potential reimbursement for personal medical costs or Worker’s Compensation Claims.

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Per campus policy, all fires must be reported to 9-911 immediately – even if the fire is out. This is particularly true if there is use of an extinguisher (must be replaced); an injury; or property damage.

Safety Data Sheets (SDS): Per OSHA, all lab chemical users must know: a) what an SDS is, b) SDS relevance to their health and safety, c) how to readily access them. These issues are all covered in the EH&S lab safety orientation program.

Labs are encouraged to maintain their own SDS for the hazardous chemicals they routinely use

Each lab space has its own SDS book that is updated on a regular basis. The security desk in the front of the school also has its own SDS book in case of a fire.

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Background: Standard Operating Procedures

Per the OSHA Standard, a complete CHP includes Standard Operating Procedures (SOP) to aid workers in minimizing chemical exposures in the lab. This is generally interpreted to mean SOPs for the following - not for all possible chemical operations:

• Operations involving what OSHA specifically designates as Particularly Hazardous Substances (PHS), namely, “Select” Carcinogens, Highly acute toxins, Reproductive toxins

• Other “high-hazard” chemical operations

Standard Operating Procedure: Use of “Particularly Hazardous Substances”

Per OSHA, Particularly Hazardous Substances (PHS) are “Select” Carcinogens, Reproductive Toxins and Highly Acute Toxins. Web-links to definitions and lists of these materials are below.

This generic PHS SOP is provided for use by campus labs. Lab supervisors are responsible for editing, or augmenting this generic SOP as necessary given their local usage conditions. If a particular procedure below cannot be feasibly followed, then alternative techniques that offer equivalent protection should be documented herein. While this broad SOP is for PHS as a whole, supervisors should develop SOPs for specific PHS, or classes of related PHS, if necessary for adequate worker safety.

Date of last revision to SOP: September 2012

a. Laboratory SOP

USE OF PARTICULARLY HAZARDOUS SUBSTANCES (PHS) “Select” Carcinogens - includes carcinogens which are further regulated by OSHA, e.g. formaldehyde, dichloromethane, benzene, cadmium compounds and arsenic compounds. • Cacodylic Acid Sodium Salt • Chloramphenicol • Chlora-san • Cobalt (II) Chloride Hexahydrate • DE CE CO • Dimethyl Sulfoxide (DMSO) • DRI CAV • Dry Wash II • Energized 36 • Ethidium Bromide Solution • Glutaraldehyde • Hydralazine HCl 13a-5 Updated March 2017

• Metasyn 35 • Nickel Chloride Hexahydrate • Nitrilotriacetic Acid • Phenytoin sodium • Streptozotocin • Triton 28 • Triton X-100 • Ultraviolet Radiation – Broad Spectrum • Viscerock

Reproductive toxins

. (+/-)-1-Phenyl-2,3-4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrobromide . (R)-(+)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3- benzazepine hydrochloride . (RS)-(+/-)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl) methyl]-2- methoxybenzamide . (S)-(-)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl) methyl]-2- methoxybenzamide . Cacodylic Acid Sodium Salt . Chloramphenicol . DE CE CO . Diazoxide . Dimethyl Sulfoxide (DMSO) . DRI CAV . Dry Wash II . Energized 36 . Ethylenediamine Tetraacetic Acid . Glutaraldehyde . Metasyn 35 . Nifedipine . Nitrilotriacetic Acid . Odorless . Streptomycin Sulfate . Streptozotocin . Sulfuric acid . Triton 28 . Trypan Blue Stain . Viscerock

13a-6 Updated March 2017

• (RS)-(+/-)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl) methyl]-2- methoxybenzamide • (S)-(-)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl) methyl]-2- methoxybenzamide • Cacodylic Acid Sodium Salt • Dimethyl Sulfoxide (DMSO) • Hydrochloric Acid • Sodium selenite

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1. Approval Required All individuals who have access to the lab space are required to go through a safety training program before using any of the chemicals and to observe a faculty member or research staff demonstrate their use while learning. 2. Personal Protective Equipment

It is recommended that all personnel entering the lab facilities wear personal eye protection, gloves, and mask. Additional PPE is available for those who choose to wear it (i.e., disposable gowns, shoe covers and hair bonnets).

It is mandatory to wear "all" PPE when working in or utilizing the BSLII areas. It is also necessary to attend the PPE training session prior to working in or utilizing these areas.

Shorts or short clothing are not acceptable laboratory work attire. Sandals and open-toed shoes are also not acceptable.

Gloves, freezer gloves, face shields, goggles, headphones, lab coats, and face masks are provided in every lab even when the dangerous chemicals are not present. Respirators are present in areas that require them.

Use of PHS shall, whenever feasible, employ the following:

• Protective eyewear such as approved safety glasses, goggles or face shields. The latter should be used when handling corrosives in large quantities (e.g. > 1 gallon).

• Lab coats, particularly when using PHS that are readily absorbed through the skin, or are corrosive to skin tissue.

• Lab gloves which are chemically-resistant to the particular material. Note that some common carcinogens such as dichloromethane and benzene readily permeate common lab gloves such as neoprene and nitrile. Disposable gloves shall be discarded after each use, immediately after known contact with a chemical carcinogen, and upon becoming visibly wet with either a chemical or biological material. See Appendix B for further details on the duration of glove usage when utilizing a certain chemical.

• All respirators, other than dust masks, must be issued and approved by EH&S to meet OSHA requirements (29 CFR 1910.134(c) (2) (ii)). Everyone using a respirator must go through proper training and read the safety manual section called “Respirators”. Training will and must cover proper uses, maintenance and storage of all respirators which are held within a working area. Supervisors must implement a program showing that routine maintenance is done in compliance with federal standards as listed in the above CFR and the manufacture of the respirator.

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3. Personnel Practices

• Pipetting: Mechanical pipetting aids will be used for all pipetting procedures. Mouth pipetting is prohibited.

• Autoclaves: Open autoclave doors slowly, standing to one side to prevent burns from steam. Wear heat resistant gloves when removing items in the autoclave. Do not attempt to open the door of an autoclave that still contains pressure in the chamber.

• Eating, drinking and smoking is prohibited in laboratory areas. Food may not be stored in laboratory refrigerators or cold rooms nor can it be heated in laboratory microwaves.

• Personal Hygiene: All personnel must wash hands after completing procedures involving biological or chemical materials. Furthermore, personnel must wash or shower areas of the body that came in direct contact with either biological or chemical materials.

• Housekeeping: Maintain good housekeeping habits. Do not allow aisles and work areas to become cluttered with chairs, stools, tables, boxes, etc. Aisles, especially exit aisles must be kept free of clutter at ALL times.

• Safety Equipment: Learn the location and use of fire extinguishers, fire blankets, water hoses, fire alarms, safety showers and eyewashes.

• Fume Hoods: Avoid inhaling chemical vapors and gases. Use fume hoods whenever possible. Do not store materials in fume hoods. Keep hoods clear and clean.

• Utilities: Set up experiments so that it is not necessary to reach through the assembly to turn water, gas or electricity on or off.

• Do not heat a closed system

• Use boiling chips when heating liquids to the boiling point

4. Engineering/Ventilation Controls

All fume hoods, biosafety cabinets and water system filters are checked on every year for prevention maintenance and recertification. • Volatile, or dust/aerosol-producing PHS must be used in a fume hood, glove box, ducted biosafety cabinet, or EH&S-evaluated snorkel exhaust. Use on the open bench is

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prohibited except when it is impractical (i.e. equipment will not fit in hood), in which case other controls (e.g. respirator) must be employed.

• When used outside of the above containment devices, containers must be sealed. Note that the use of volatile PHS such as formalin, dichloromethane and benzene on an open lab bench, in open containers, would probably result in worker exposures above the OSHA legal/safe limits for such materials.

5. Procedures to Maintain a Safe Environment

The Occupational and Environmental Safety Department conducts periodic laboratory inspections of each department, its physical facilities, equipment and hazards. The purpose of safety inspections is to identify and implement actions necessary to protect employees and students from injuries before they occur.

The safety inspections are formal and the findings are documented. Informal safety inspections are when a brief observation of an area is made and the findings or corrective actions may or may not be written down. After the Occupational and Environmental Safety Department conducts laboratory inspections, a report of the inspection is sent to the PI and laboratory manager for review. If there are recommendations for corrective actions, PI’s and laboratory managers must determine the corrective action.

6. Laboratory Injuries

In cases of inhalation, ingestion, dermal absorption and injection of chemicals or biologicals, initiate emergency procedures listed below and follow up with first aid measures. Have your supervisor complete an Employee Incident Report after the injury occurs.

• Eye Exposure: If chemicals or other hazardous materials (HAZMATS) get into the eyes, use an eye wash. Flush eyes with water for at least fifteen (15) minutes. Eyelids may have to be forcibly held open.

• Chemical Burns and Skin Absorption: For chemical burns and skin absorption of chemicals, flush affected areas with copious amounts of cool water or use the nearest safety shower.

• Inhalation/Ingestion/Asphyxiation: For incidents of inhalation, ingestion, asphyxiation or suffocation of/from toxic substances, eliminate the source of the problem if possible. In all cases, remove the person from the area and seek medical attention immediately.

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7. Any Special Chemical Handling, Storage, Cleanup or Disposal Requirements

a. Under the CHP law, an area must be designated for working with PHS. The designated area may be the entire laboratory, an area of the lab, or a device such as a laboratory hood. At GA-PCOM, the designated PHS work area is the entire laboratory, unless the supervisor specifies otherwise herein; either in general, or for a specific material or operation.

. PHS must be stored in completely-sealed containers. Although hood storage of chemicals is generally discouraged, volatile PHS can be stored in a fume hood if deemed necessary.

. Spills of PHS must be completely cleaned up. Spills that cannot be safely and completely handled by lab personnel must be reported to EH&S for assistance.

• The following materials are very hazardous. You should not clean them up yourself. -Aromatic amines -Hydrazine -Bromine -Organic Halides -Carbon disulfide -Nitriles -Cyanides -Nitro compounds -Ethers and other 1A flammable solvents

. Like all chemical wastes, disposal of PHS must be done through EH&S. No PHS, or other chemical wastes can go into the sewer system, trash or be allowed to freely evaporate.

. Hazardous chemicals and/or byproducts that cannot be disposed of on the premises are to be labeled and safely packaged centrally for annual pick-up usually in the winter. All departments are notified as to the date of pick-up. Prior to the removal of the chemicals, each department must submit to the technician disposing of the chemicals a list specifying chemical or mixture name, quantity, container type, and place of storage.

. Always confirm the proper labeling of containers with contents, concentration, manufacturer, handling precautions, and expiration date (especially in the case of unstable compounds).

. Never test chemicals by taste or odor. If in doubt, do not use an unlabeled chemical.

. Always keep in mind that acids are poured into water and NOT the other way around.

. Separate storage areas should be provided for “incompatible chemicals,” which may react and create a hazardous condition. For instance, some oxidizing acids (nitric, sulfuric, 13a-11 Updated March 2017

perchloric), when stored together with flammable solvents, can create a fire if the bottles are broken and there is contact of the two materials. Do not store chemicals by alphabetical listing. Store by acids, bases, salts, flammables, etc.

. Store cryogenic liquids such as: dry ice, liquid nitrogen, liquid helium, and any other liquefied gases in well-ventilated areas. Do not store these liquids in walk-in cold rooms because walk-in cold rooms are poorly ventilated. For example, the sublimation of dry ice will reduce the percentage of available oxygen.

8. Hazardous Chemical Materials

The following definitions have been extracted from the Code of Federal Regulations, Title 49- Transportion, Parts 100 to 177.

• Explosive: Any chemical compound, mixture, or device, the primary or common purpose of which is to function by explosion, i.e., with substantial instantaneous release of gas and heat is considered an explosive. Picric acid (in a dry state), sodium azide and ammonium trinitrate are in this class.

• Combustible Liquid: Any liquid with a flash point from 100°F to 200°F, except any mixture with one component or more with a flash point at 200°F or higher, that makes up at least 99% of the total volume of the mixture.

• Corrosive Material: Any liquid or solid that causes destruction of human skin tissue or a liquid that has a severe corrosion rate on steel, copper, aluminum or other metal used in supporting structures. Strong acids such as hydrochloric, nitric, sulfuric and hydrofluoric are included.

• Flammable Liquid: Any liquid with a flash point less than 100°F with the following exceptions: (i) A flammable liquid with a vapor pressure greater than 40 psi at 100°F, (ii) Any mixture with one component or more with a flash point of 100°F or higher that makes up at least 99% of the total volume of the mixture; and (iii) A water –alcohol solution containing 24% or less alcohol by volume if the remainder of the solution does not meet the definition of a hazardous material.

• Compressed Gas: Any material or mixture in a container with a pressure exceeding 40 psi at 70°F or a pressure exceeding 104 psi at 130°F; or any liquid flammable material with a vapor pressure exceeding 40 psi at 100°F.

• Flammable Gas: Any compressed gas meeting the requirements for lower flammability limit, flammability limit range, flame projection, or flame propagation criteria. Includes but is not limited to diazomethane, methylamines, acetylene, hydrocarbons and hydrogen.

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Oxygen and nitrous oxide, while not flammable, will support combustion.

• Nonflammable Gas: Any compressed gas other than a flammable compressed gas. Includes the inert gases (He, Ar, Ne, Kr), and nitrogen.

• Flammable Solid: Any solid material, other than an explosive, which is liable to cause fires through friction, absorption of moisture, spontaneous chemical changes, retained heat from manufacturing, or processing, or which can be ignited readily and when ignited burns so vigorously and so persistently as to create a serious transportation hazard. Includes pyrophoric compounds such as finely divided metals (calcium, titanium); metal hydrides (lithium aluminum hydride, sodium borohydride); diborane, calcium carbide, and sodium and potassium metals.

• Organic Peroxide: An organic compound containing the bivalent -0-0- structure and which may be considered a derivative of hydrogen peroxide where one or more of the hydrogen atoms have been replaced by organic radicals. Includes easily peroxidizable compounds like ethers (diethyl, isopropyl, dioxane, tetrahydroguran). Many of these pure solvents are shipped with peroxide inhibitors.

• Oxidizer: A substance such as chlorate, permanganate, inorganic peroxide, nitro carbonitrate, or a nitrate, that yields oxygen readily to stimulate the combustion of organic matter.

• Poisonous: Poisonous substances, in solid, liquid or gaseous form, which are known to be toxic to humans and pose a hazard to health during transportation; or which in the absence of adequate data on human toxicity, are presumed to be toxic to humans.

• Irritating Material: A liquid or solid substance which upon contact with fire or when exposed to air, gives off dangerous or intensely irritating fumes.

• Infectious Substance: A viable microorganism or its toxin which causes or may cause severe, disabling or fatal disease in humans or animals.

• Radioactive Material: Any material or combination of materials, that spontaneously emits ionizing radiation and which has a specific activity greater than 0.002 microcuries per gram.

(including a solid when wet with water) capable of causing significant damage to a transport vehicle or vessel from leakage during transportation. (iii) Materials which have other inherent characteristics not described above but which make them unsuitable for shipment, unless properly identified and prepared for transportation.

Flammable Liquids

Introduction:

In any fire or explosion occurring in a laboratory at PCOM, the severity of the fire will depend on the extent on the amount of flammable liquids in the area and how they are stored. This section establishes maximum amounts of flammable liquids for various laboratories and describes the types of containers to be used for various chemicals.

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Definitions of Flammable and Combustible Liquids:

Flammable: Class IA Flashpoint below 73oF (23oC) and boiling point below 100oF (38oC)

Class IB Flashpoint below 73oF (23oC) and boiling point at or above 100oF (38oC)

Class IC Flashpoint at or above 73oF (23oC) and below 100oF (38oC)

Combustible:

Class II Flashpoint at or above 100oF (38oC) and below 140oF (60oC)

Class III Flashpoint at or above 140oF (60oC) Storage

All flammable and combustible liquids not in use in a laboratory must be stored in approved storage cabinets or approved storage rooms. Special storage facilities must be provided for materials which have uniquely hazardous properties such as temperature- sensitivity, water-reactivity, or explosive materials.

Although OSHA and NFPA codes include information about flammable liquid storage cabinets, there are no requirements for venting these cabinets to the atmosphere. If, however, the owner decides to vent the cabinet, there are requirements which must be followed to ensure that venting of the cabinet does not create more problems than it solves. When the vent caps are removed from the cabinets, flame arrestors must be inserted. Then, metal ducting must be attached to the lower vent while the upper one is left open. The ducting must lead to an explosion proof blower/motor in order to exhaust the fumes to the atmosphere. Exhausting by diffusion is not considered adequate to provide a safe work environment.

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The storage of flammable liquids must be kept to a minimum. Generally speaking, no more than 10 gallons of flammable liquids should be stored outside flammable liquid storage cabinets or flammable liquid safety cans. Where provided, all flammable material should be returned to the flammable storage cabinet at the end of the day. Storage cabinets and cans should bear approved labels from UL (Underwriters Laboratories) or FM (Factory Mutual).

Flammable liquid storage in laboratories is regulated by the NFPA and the City of Philadelphia Fire Prevention Code. Evaluation of flammable liquid storage in your laboratory can be made by the Occupational and Environmental Safety Department.

Storage of chemicals other than flammable liquids and solids in flammable cabinets must be avoided since many chemicals (i.e. acids) can degrade the metal and ruin the integrity of the cabinet. This can result in the collapse of shelves and mixture of incompatible material resulting in a possible fire or release of toxic gases.

Dispensing:

• Dispensing of flammable or combustible liquids must be carried out under a fume hood or in an approved storage room.

• All drums containing flammable liquids for dispensing must be vented with approved safety bungs.

• Only drum pumps or self-closing faucets should be used.

• All drums and all equipment subject to static accumulation must be grounded.

• Dispensing should only be into approved containers, and any metal containers must be grounded to the drum.

• All ignition sources must be eliminated from the area.

• Good housekeeping standards should be maintained, and if possible, all combustible materials eliminated, particularly where flammable liquids are located.

• Portable fire extinguishing equipment must be provided such as portable dry chemical, foam, or carbon dioxide units.

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• Do not dispose flammable or combustible liquids into sinks or drains.

Disposal:

Department personnel should provide an accurate description of all chemical constituents within the waste container. Unknown chemicals present serious problems for the chemical waste management program. Waste management personnel cannot handle or dispose of unknown chemicals or chemical mixtures in a safe manner; therefore, analysis is required, which is very costly.

Peroxidizable Liquids

Peroxide formation in solvents and reagents has been responsible for many serious explosions in laboratories and, therefore, presents a potential hazard. Under normal storage conditions, some chemicals can form and accumulate peroxides which explode violently when shocked or heated. The following information is, therefore, designed to enable a worker to recognize peroxidizable compounds, to test for peroxides, and to handle them safely.

Recognition:

There are essentially 10 major structures that readily form peroxides. As determined from the literature, the first 6 have caused numerous explosions and the last 4 very few.

1. Ethers, acetyls;

2. Olefins with allylic hydrogen, chloro- and fluoro-olefins, terpenes, tetrahydronaphthalene

3. Dienes, vinyl cetylene;

4. Vinyl monomers including vinyl halides, acrylates, methacrylates, vinyl esters;

5. Alkali metals such as potassium

6. Alkali metal, alkoxides and amines such as sodamine;

7. Paraffinic and allyl aromatic hydrocarbons, particularly those with tertiary hydrogen;

8. Organometallics such as Grignard reagent;

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9. Aldehydes, ketones; anhydrous acetaldehyde (will undergo oxidation at 0oC or below; will undergo catalysis under ultraviolet light to form peracetic acid, which may react with more acetaldehyde to give the explosive acetaldehyde monomer acetate);

10. Ureas, amines, and lactams.

The more volatile the peroxidizable compound, the more likely that peroxides can be formed. Pure compounds are more subject to peroxide accumulation. Impurities may inhibit peroxide formation or catalyze their slow decomposition. Peroxide accumulation involves a balance between peroxide formation rate and degradation rate under the environment of a given compound. For example, certain highly reactive compounds such as organometallics accumulate peroxides at low temperatures because the peroxide degradation rate is slowed relative to formation rate. In contrast, less reactive compounds such as hydrocarbons or ethers are usually best kept at low temperature.

Purchase:

After making a chemical purchase, laboratory personnel should label all chemicals that are in the following lists with the date of purchase. When possible, commercial solvents should be purchased with peroxide inhibitors incorporated into them.

The chemicals below must be labeled as containing peroxides.

Group 1 (3 months) Group 3 (12 months)

Divinyl acetylene Acrylic acid Isopropyl ether Acrylonitrile Potassium metal Butadiene Sodium azide Chloroprene Vinylidene chloride Chlorotrifluoroethylene Methyl methacrylate Group 2 (6 months) Styrene Tetrafluoroethylene Acetal Vinyl acetate Cumene Vinyl acetylene Cyclohexene Vinyl chloride Diacetylene Vinyl pyridine Dicyclopentadiene Diethyl ether Dimethyl ether Dioxane Ethylene glycol dimethyl ether Glyme Methyl acetylene

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Methyl isobutyl ketone Methylcyclopentane Tetrahydrofuran Tetrahydronapthalene (Tetralin) Vinyl ethers

The peroxide hazard from Group 1 is derived solely from storage. Group 2 presents a peroxide hazard upon concentration (evaporation, etc.), and Group 3 is hazardous upon peroxide initiation during polymerization. When stored as a liquid, the peroxide forming potential of the Group 3 chemicals increases and certain of these monomers (especially butadiene, chloroprene and tetrafluorethylene) should then be considered as Group 1 compounds.

Storage:

• All peroxidizable compounds should be stored away from heat and light. Sunlight is an especially good promoter of peroxidation.

• Peroxidizable liquids should be stored in metal cans if possible. Particular care should be given to ensure good closure of storage containers. Whenever possible, store peroxidizable compounds (except certain inhibited vinylmonomers) under a nitrogen atmosphere.

• All containers with peroxidizable chemicals should be protected from physical damage and ignition sources.

• Group 1 materials, those which accumulate peroxides to a hazardous level simply on storage, must be evaluated for peroxide content at least every three months after opening. They should be re-dated if safe or disposed of in an approved manner if the peroxide level is high.

• Group 2 and Group 3 materials should not be stored for longer than twelve months after opening unless shown by a suitable test not to have accumulated peroxide. Discretion must be used with respect to storage after opening. Should it be desirable to retain Group 2 or 3 materials which give a positive test for peroxide, the material must be treated to remove the peroxide, rebottled, and the label re-dated.

• Quantities of uninhibited vinyl monomers greater than 500 g. should not be stored for longer than 24 hours. For storage in excess of 24 hours, quantities of vinyl monomers greater than 10 g. should be inhibited with a suitable inhibitor. The name and quantity of the inhibitor should be indicated on the label. Storage of less than 10 g. of an inhibited vinyl monomer for longer than a 24-hour period should be done only with discretion.

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• When handling peroxidizable compounds stored in cylinders, care must be taken to ensure that the cylinders are maintained free of air.

• All peroxidizable liquids, whether open or not, should never be used or stored beyond the expiration date printed on the container.

Ethyl Ether

Storage and Quantity:

A laboratory should never keep more than a total of 3 lb. (1.4 kg) of individually dated containers of ethyl ether on hand. Ether should not be stored near acids or caustics, particularly anhydrous nitric acid. Ether can react slowly with oxygen to form explosive peroxides. The rate of formation depends upon the particular ether and storage conditions. When not in use, ether should be stored in flammable liquid storage cabinets or explosion proof refrigerators.

Required Safe Practices:

• Use the grade of ether designed for the procedure. Do not use anhydrous ether unless the procedure requires it.

• Lab shelf storage must be in approved safety cans. Newly acquired cans of ether should be dated and kept no longer than 6 months after opening and never beyond the expiration date printed on the container.

• Lab personnel must wear personal protective equipment (including eye protection).

• Ether spills can be absorbed with a wet sponge or paper towel. The wet material must be placed in a fume hood for vapor evaporation.

• When ether is transferred to another container, the new container must be properly labeled. The new container should not be glass.

• For disposal of large quantities of ether, call the Occupational and Environmental Safety Department at extension 6360.

Hazards:

Ether has a relatively low toxicity, especially in the context of laboratory use. However, it is extremely flammable with a flashpoint of -45oC.

CO2, ABC, or BC dry powder fire extinguishers are to be used in areas with ether.

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Good general ventilation is required. The Occupational and Environmental Safety Department should be contacted to determine adequacy of local ventilation in areas in which ether is used.

9. Safe Handling of Carcinogens, Mutagens, and Teratogens

General Information:

• Chemical carcinogens, mutagens, and teratogens are used in many laboratories at PCOM. In order to protect both the workers and the community from health hazards associated with the use of these substances, each cancer-causing compound must be recognized as a carcinogen and handled with the appropriate precautions.

• A wide variety of compounds have been found to be carcinogenic for experimental animals. In some instances, these compounds have been identified as potential human carcinogens. In other cases, the compounds are suspected of being human carcinogens, although definitive scientific evidence does not currently exist. All compounds that cause cancer in any species must be regarded as potentially hazardous to humans.

• Several references on carcinogens are available from the Occupational and Environmental Safety Department. Several organizations compile lists on carcinogens including the International Agency for Cancer Research (IRAC) Monographs, the National Institute of Occupational Safety and Health (NIOSH), and the National Toxicology Program (NTP) Annual Report on Carcinogens.

• When possible, non-carcinogenic substances should be substituted for chemical carcinogens. If substitution is not possible, care must be taken to avoid exposure through inhalation, ingestion, and absorption through the skin.

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Below are listed some of the types of chemicals that are known to have carcinogenic, mutagenic, and/or teratogenic health effects. The hazard will depend on the specific substance and concentration being used.

Acetamide 2,4-DichloropHenol Lithium chloride Aniline hydrochloride Diphenylamine Methyl ethyl ketone Benzene Ethidium bromide Nickel(ous) ammonium sulfate Benzidine Ethylene dichloride Nickel(ous) chloride Cadmium chloride Ferric oxide Nickel(ous) sulfate Cadmium nitrate Formaldehyde Phenol Carbon tetrachloride Isoamyl alcohol 1-Propyl alcohol Chloroform Isobutyl alcohol Pyrogallic acid Chromic acetate Kerosene Salicyclamide Chromic acid Lauric acid Sodium chromate Colchicine Lead acetate Sodium dichromate Dichloromethane Lead chloride Tannic acid 1,2-Dichlorobenzene Lead nitrate Thioacetamide

Chemical Review and Approval:

The Occupational Health and Safety Administration requires special consideration be given to work involving particularly hazardous chemicals. At PCOM, research involving the use of carcinogens, mutagens and other toxins is reviewed by the Occupational and Environmental Safety Department.

10. Chemical Waste Disposal

Most laboratories using chemicals in their activities will produce chemical wastes requiring regulated disposal. At PCOM, the Occupational and Environmental Safety Department has responsibility for the safe and legal management of hazardous chemical wastes. A multifaceted program has been developed to accomplish this goal. The procedures outlined in this section are designed to promote: (i) safe handling of wastes to prevent spills and other accidents, (ii) an efficient disposal process for all concerned, and (iii) compliance with all applicable regulations governing hazardous wastes. Regulatory Overview:

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PCOM must comply with a variety of environmental legislation. The most comprehensive set of regulations governing hazardous waste management and disposal was promulgated in 1980 by the Environmental Protection Agency (EPA) as the Resource Conservation and Recovery Act (RCRA) and its later amendments. The Pennsylvania Department of Environmental Protection has authorization to administer and enforce these regulations in Pennsylvania. These regulations serve primarily to designate which wastes are hazardous, as well as how they must be handled, stored, disposed or recycled.

Waste Definitions:

The RCRA regulations include a list of several hundred chemicals which are specifically designated as hazardous wastes. This list includes most common solvents, many reagents, acids, toxic substances, and other industrial and/or laboratory chemicals. Since such a list could never include all possible hazardous wastes, there are four general characteristics used to define non-listed materials as hazardous wastes. These characteristics are ignitable, corrosive, toxic, and reactive. Most chemical wastes generated in a laboratory setting can be considered hazardous in one form or another and should be treated as such. If there is any question regarding the handling of a chemical waste, even if considered non- hazardous, call the Occupational and Environmental Safety Officer in the Occupational and Environmental Safety Department for assistance.

Ignitable

This category refers to solvents with a flash point of less than 60oC. Typical ignitable solvents used in labs include alcohols (methanol, isopropanol, etc.), aliphatic hydrocarbons (pentane, hexane), ketones (acetone, MEK), and aromatic compounds such as benzene, toluene, and xylene.

Corrosive

As described in the EPA Regulations, this group of chemicals includes acids of pH less than 2, and bases of pH greater than 12.5. Local regulations prohibit disposal of materials with a pH less than 6 and greater than 9 to the sewer. Small quantities of acids and bases may be neutralized in the laboratory.

Toxic

This is a very broad category which refers to chemicals which may be injurious to human health through inhalation, ingestion, or skin contact. Typical laboratory wastes which are included in the toxic category are metals, stains, and DNA extraction chemicals. Other toxic materials include pesticides and carcinogens.

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Reactive

Chemicals in this category are either inherently unstable, or upon contact with other materials react violently or release toxic gases. Typical reactive materials which may be part of a laboratory's waste stream are cyanide compounds, strong oxidizers such as potassium permanganate and perchloric acid, metallic sodium and potassium, picric acid, butyl lithium, old ethers which may have formed peroxides, and explosive salts such as sodium azide. Reactive materials must be treated with extreme caution to protect not only the personnel in the laboratory, but also those who handle and package the material for its disposal process. Because of the considerable cost associated with disposal of reactive wastes, purchase volumes should be minimized and in-house reduction techniques should be explored to render reactives less hazardous prior to entering the disposal route. Laboratories generating a reactive chemical waste stream must have these materials collected regularly to prevent large quantities from accumulating.

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Specific materials which cannot be put into laboratory drains under any circumstances include:

• Solids large enough to plug lines

• Combustible, flammable or explosive wastes

• Wastes which are toxic or inhibitory to biological waste treatment

• Large quantities of water insolubles which may settle and plug lines

• Highly reactive materials (i.e., strong oxidizers such as phosphorous oxychloride)

• Radioactive materials • Carcinogenic agents or suspected carcinogens

• Corrosive wastes that cannot be neutralized

• RCRA listed wastes

Ethidium Bromide Waste

Ethidium bromide(EtBr) is a potent mutagen used as a fluorescent stain for visualizing nucleic acids in life sciences research. Proper management of EtBr waste is important. The following guidelines are offered for various waste streams containing EtBr.

Aqueous Solutions of EtBr

Aqueous solutions containing less than 10 µg/ml EtBr may be disposed to the sanitary sewer. Solutions containing greater than 10 µg/ml EtBr must either be surrendered to the Chemical Waste Program before disposal to the sanitary sewer. Solutions can also be filtered using any of the commercially available EtBr filter units. The filtered material must then be placed into the Chemical Waste Program.

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Acrylamide and Agarose Gels Containing EtBr

All gels containing EtBr are to be surrendered to the Chemical Waste Program.

Alcohol Solutions of EtBr

Combined EtBr and alcohol solutions are flammable. Therefore, regardless of the concentration of EtBr, all of this material must be surrendered to the Chemical Waste Program.

Lab ware contaminated with EtBr

Contaminated lab ware includes needles and syringes, test tubes, pipettes, etc. Depending upon the type of waste that you generate, follow the appropriate procedures for those materials using the 10 µg/ml rule previously applied. Those items with less than 10 µg/ml EtBr can essentially be disposed without regard to the EtBr. (i.e. sharps into sharps containers, glass into glass disposal boxes, etc ) All lab ware with greater than 10 µg/ml EtBr contamination will need to be decontaminated then disposed accordingly or, if not inactivated, surrendered to the Chemical Waste Program in an acceptable container.

11. Laboratory Procedures

Planning

Before an experiment or research project begins, some consideration should be given to what types of chemical wastes the process will produce. Segregation of wastes that follow different disposal routes is an important component of an efficient disposal process. Before generation of the waste begins, the laboratory must have proper containers and labels. The laboratory should also have someone designated as the person responsible for coordinating collection of the wastes.

Waste Minimization

Each researcher has a legal responsibility as well as a moral obligation to make every reasonable effort to minimize the hazardous waste volume generated by his/her laboratory. This can be accomplished by several methods such as miniaturization of the experimental process, avoidance of unnecessary experiments, and a change to using biodegradable chemical products or “greener” alternatives. Researchers should also document their waste minimization strategies with the Occupational and Environmental Safety Department.

Labeling

waste containers is also important while the material is still in the laboratory. It aids in the proper segregation of different waste types and helps to prevent lab personnel from inadvertently mixing incompatibles together in the same waste container. The third major purpose for a properly labeled container dictates the correct disposal route to be followed after collection. A label which reads "waste solvents" or "organic waste" is not useful. Wastes labeled as such or not labeled at all are refused until sufficient analysis is performed to properly characterize the material.

Materials collected for disposal must be prepared as follows:

• Materials must be identified with labels stating contents, lab contact, and phone number. • Waste solvents which are compatible must be in either 5 gallon poly carboy containers or in glass jugs of not more than one gallon capacity. All containers must have a screw-type closure (no corks or plugs).

• Miscellaneous laboratory reagents must be in strong, tight containers and must have a positive- type closure in good condition (no corks or plugs).

• Waste acids cannot be mixed and must also be in glass jugs of not more than one gallon capacity. They too must have a screw-type closure (no corks or plugs).

Laboratory Relocation/Chemical Moves:

Occasionally laboratories will relocate to another building on campus. Moving companies contracted by the University will not move chemicals. The transporting of hazardous materials is regulated by the Department of Transportation (DOT). Anyone offering for transport, packaging or transporting hazardous materials must do so under the requirements contained in the Code of Federal Regulations Chapter 49. Individuals/companies who violate these regulations can be held liable and are subject to fines/imprisonment. Therefore, contact the Occupational and Environmental Safety Officer for assistance in moving chemicals to a new location on campus.

12. Hazard Communication

Under Pennsylvania and OSHA regulations, all employees have a right to know the potential toxic effects of the substances to which they are potentially exposed. Employees must receive education and training regarding toxic materials prior to being assigned to work with them. No employee is to work with a material until he or she has been made familiar with the hazards and is comfortable working with it.

Supply Chain Management requests Safety Data Sheets (SDSs) from the manufacturer or supplier at the time chemicals are ordered. The manufacturer forwards the SDS to the Occupational and Environmental Safety Department, where they are maintained in a reference library. In addition, each laboratory is required to have SDSs available for the hazardous chemicals used in their lab.

These SDSs can also be obtained through MSDSonline®. Any questions about the use of this service or about Safety Data Sheets can be directed to the Occupational and Environmental Safety

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Department.

SDSs contain detailed information about chemicals and are to be reviewed PRIOR to working with any hazardous chemical for the first time. Any employee who has a question regarding hazardous material may contact the Occupational and Environmental Safety Department for information and assistance.

13. The OSHA Laboratory Standard

In 1990, the Occupational Safety & Health Administration (OSHA) enacted “Occupational Exposure to Hazardous Chemicals in Laboratories”, a regulation known commonly as the “Laboratory Standard.” This federal law requires employers to take measures to safeguard employees against exposures to hazardous chemicals in laboratories. If you meet the definition of “laboratory” under the standard, you are covered and must meet the requirements listed below.

OSHA defines “laboratory” as a facility where the laboratory use of hazardous chemicals occurs. It is a workplace where relatively small quantities of hazardous chemicals are in use on a non- production basis.

REQUIREMENTS:

Employee Exposure Determination

An employee’s exposure to a hazardous chemical must be measured if there is reason to believe that exposure levels routinely exceed an action level or permissible exposure limit (PEL).

Chemical Hygiene Plan

The employer must develop and implement a written Chemical Hygiene Plan (CHP). It must cover practices, policies, and procedures for protection against hazardous chemical exposure and must be available to ALL employees and volunteers.

Employee Training and Information

It is the responsibility of each employer to provide its employees with education and training regarding potentially toxic materials. The employer must provide employees with information and training to ensure that they are aware of the hazards of the chemicals present in their work areas. This information must be provided at the time of the employee’s initial assignment to a work area where hazardous chemicals are present and prior to assignments involving new exposure potentials. There must be documentation that training was provided. The following items must be addressed as part of the education program:

Employees must be informed of:

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• the contents of the Laboratory Standard. • location and availability of the CHP. • PELs for hazardous chemicals used in the lab. • signs and symptoms associated with exposures to hazardous chemicals. • location and availability of Safety Data Sheets (SDS).

Employees must be trained on:

• methods to detect the presence or release of a hazardous chemical used in the lab. • physical and health hazards of chemicals in the work area. • procedures to protect themselves against exposure to hazardous chemicals. • details of the employer’s written CHP.

Medical Consultation and Examination

Employees must be given the opportunity to receive medical attention whenever (i) they exhibit signs or symptoms related to hazardous chemical exposure; (ii) monitoring reveals that action levels or PELs are routinely exceeded; or (iii) an incident or spill results in the likelihood of an exposure to the employee. Medical evaluation must be provided by the employer at no cost to the employee.

Hazard Identification

Labels on containers of chemicals must not be defaced or removed. SDSs must be made available to laboratory employees. In addition, all bottles within the work place must be labeled as the original bottle is labeled OR with the product identifier and words, pictures, symbols, or combination thereof which provide at least general information regarding the hazards of the chemical, and which, in conjunction with the other information immediately available to the employee under the hazard communication program, will provide employees with the specific information regarding the physical and health hazards of the hazardous chemical. No abbreviations are permitted. (For example, a bottle may not be labeled just as “Base;” it also must be labeled with the ingredients. Also, using an abbreviation such as “NaOH” is not permitted; it must be written out as “Sodium Hydroxide.”) SDSs must be made available to laboratory employees.

Respirator Use

When the risk of employee respiratory exposure to potentially hazardous chemical substances exists, attempts to minimize employee exposure should be made through engineering controls, i.e. local exhaust ventilation, chemical fume hood. If such measures are not available or feasible, the use of personnel protective respiratory equipment may be necessary. Before any employee can wear a respirator they must contact the Occupational and Environmental Safety Department to achieve compliance to OSHA’s Respiratory Protection Standard (CFR 1910.134).

Where respirators are necessary to maintain exposure levels below the PEL, the employer must provide them at no cost to the employee.

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14. Safety Data Sheets (SDS)

Federal regulations require chemical manufacturers to provide specific safety information on their chemical products to anyone who purchases them. This information is communicated through a

standardized information sheet(s) called a Safety Data Sheet, otherwise known as a SDS. SDSs may vary in appearance depending upon the manufacturer; however, all must contain the following 16 sections:

1. Identification 2. Hazard(s) identification 3. Composition/information on ingredients 4. First-aid measures 5. Fire-fighting measures 6. Accidental release measures 7. Handling and storage 8. Exposure controls/personal protection 9. Physical and chemical properties 10. Stability and reactivity 11. Toxicological information 12. Ecological information 13. Disposal Considerations 14. Transport information 15. Regulatory information 16. Other information, including date of preparation or last revision

SDSs are a valuable source of information to laboratory staff working with hazardous chemicals. SDSs should be reviewed prior to working with the chemical(s) for the first time and periodically as needed. Copies of SDS’s can be obtained from the Occupational and Environmental Safety Department. The SDS may be kept either on the computer or in a binder within the laboratory, which is immediately accessible to any laboratory personnel.

Note: Whenever a new chemical is ordered at PCOM, the manufacturer forwards the SDS to the Occupational and Environmental Safety Department. All SDSs are kept on file and are readily accessible to anyone who requests safety information on a particular chemical.

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Appendix A: EPA List of Hazardous Wastes

EPA Hazardous Waste # Chemical abstracts # Substance P023 107-20-0 Acetaldehyde, chloro- P002 591–08–2 Acetamide, N-(aminothioxomethyl)- P057 640–19–7 Acetamide, 2-fluoro- P058 62–74–8 Acetic acid, fluoro-, sodium salt P002 591–08–2 1-Acetyl-2-thiourea P003 107–02–8 Acrolein P070 116–06–3 Aldicarb P203 1646–88–4 Aldicarb sulfone. P004 309–00–2 Aldrin P005 107–18–6 Allyl alcohol P006 20859–73–8 Aluminum phosphide (R,T) P007 2763–96–4 5-(Aminomethyl)-3-isoxazolol P008 504–24–5 4-Aminopyridine P009 131–74–8 Ammonium picrate (R) P119 7803–55–6 Ammonium vanadate P099 506–61–6 Argentate(1-), bis(cyano-C)-, potassium P010 7778–39–4 Arsenic acid H3AsO4 P012 1327–53–3 Arsenic oxide As2O3 P011 1303–28–2 Arsenic oxide As2O5 P011 1303–28–2 Arsenic pentoxide P012 1327–53–3 Arsenic trioxide P038 692–42–2 Arsine, diethyl- P036 696–28–6 Arsonous dichloride, phenyl- P054 151–56–4 Aziridine P067 75–55–8 Aziridine, 2-methyl- P013 542–62–1 Barium cyanide P024 106–47–8 Benzenamine, 4-chloro- P077 100–01–6 Benzenamine, 4-nitro- P028 100–44–7 Benzene, (chloromethyl)- P042 51–43–4 1,2-Benzenediol, 4-[1-hydroxy-2- (methylamino)ethyl]-, (R)- P046 122–09–8 Benzeneethanamine, alpha,alpha-dimethyl- P014 108–98–5 Benzenethiol P127 1563–66–2 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, methylcarbamate. P188 57–64–7 Benzoic acid, 2-hydroxy-, compd. with (3aS- cis)-1,2,3,3a,8,8a- hexahydro-1,3a,8- trimethylpyrrolo[2,3-b ]indol-5- P001 81–81–2 2H-1-Benzopyran -2-one, 4-hydroxy -3-(3 -oxo - 1-phenylbutyl)-, & salts, when present at concentrations greater than P028 100–44–7 Benzyl chloride P015 7440–41–7 Beryllium powder P017 598–31–2 Bromoacetone

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P018 357–57–3 Brucine P045 39196–18–4 2-Butanone, 3,3-dimethyl-1-(methylthio)-O- [methylamino)carbonyl]oxime P021 592–01–8 Calcium cyanide P021 592–01–8 Calcium cyanide Ca(CN)2 P189 55285–14–8 Carbamic acid, [(dibutylamino)- thio]methyl-, 2,3-dihydro-2,2- dimethyl- 7-benzofuranyl ester. P191 644–64–4 Carbamic acid, dimethyl-, 1-[(dimethylamino)carbonyl]- 5- methyl-1H- pyrazol-3-yl ester. P192 119–38–0 Carbamic acid, dimethyl-, 3-methyl-1- (1- methylethyl)-1H- pyrazol-5-yl ester. P190 1129–41–5 Carbamic acid, methyl-, 3-methylphenyl ester. P127 1563–66–2 Carbofuran. P022 75–15–0 Carbon disulfide P095 75–44–5 Carbonic dichloride P189 55285–14–8 Carbosulfan. P023 107–20–0 Chloroacetaldehyde P024 106–47–8 p-Chloroaniline P026 5344–82–1 1-(o-Chlorophenyl)thiourea P027 542–76–7 3-Chloropropionitrile P029 544–92–3 Copper cyanide P029 544–92–3 Copper cyanide Cu(CN) P202 64–00–6 m-Cumenyl methylcarbamate. P030 Cyanides (soluble cyanide salts), not otherwise specified P031 460–19–5 Cyanogen P033 506–77–4 Cyanogen chloride P033 506–77–4 Cyanogen chloride (CN)Cl P034 131–89–5 2-Cyclohexyl-4,6-dinitrophenol P016 542–88–1 Dichloromethyl ether P036 696–28–6 Dichlorophenylarsine P037 60–57–1 Dieldrin P038 692–42–2 Diethylarsine P041 311–45–5 Diethyl-p-nitrophenyl phosphate P040 297–97–2 O,O-Diethyl O-pyrazinyl phosphorothioate P043 55–91–4 Diisopropylfluorophosphate (DFP) P004 309–00–2 1,4,5,8-Dimethanonaphthalene, 1,2,3,4,10,10-hexachloro- 1,4,4a,5,8,8a,- P060 465–73–6 1,4,5,8-Dimethanonaphthalene, 1,2,3,4,10,10-hexachloro- 1,4,4a,5,8,8a- hexahydro- 13a-32 Updated March 2017

P037 60–57–1 2,7:3,6-Dimethanonaphth[2,3-b]oxirene, 3,4,5,6,9,9-hexachloro- 1a,2,2a,3,6,6a,7,7a- octahydro- P051 72–20–8 2,7:3,6-Dimethanonaphth [2,3-b]oxirene, 3,4,5,6,9,9 -hexachloro- 1a,2,2a,3,6,6a,7,7a - octahydro- P044 60–51–5 Dimethoate P046 122–09–8 alpha,alpha-Dimethylphenethylamine P191 644–64–4 Dimetilan. P047 534–52–1 4,6-Dinitro-o-cresol, & salts P048 51–28–5 2,4-Dinitrophenol P020 88–85–7 Dinoseb P085 152–16–9 Diphosphoramide, octamethyl- P111 107–49–3 Diphosphoric acid, tetraethyl ester P039 298–04–4 Disulfoton P049 541–53–7 Dithiobiuret P185 26419–73–8 1,3-Dithiolane-2-carboxaldehyde, 2,4- dimethyl-, O- [(methylamino)- carbonyl]oxime P050 115–29–7 Endosulfan P088 145–73–3 Endothall P051 72–20–8 Endrin P051 72–20–8 Endrin, & metabolites P042 51–43–4 Epinephrine P031 460–19–5 Ethanedinitrile P194 23135–22–0 Ethanimidothioc acid, 2-(dimethylamino)-N- [[(methylamino) carbonyl]oxy]-2-oxo-, methyl ester. P066 16752–77–5 Ethanimidothioic acid,N- [[(methylamino)carbonyl]oxy]-, methyl ester P101 107–12–0 Ethyl cyanide P054 151–56–4 Ethyleneimine P097 52–85–7 Famphur P056 7782–41–4 Fluorine P057 640–19–7 Fluoroacetamide P058 62–74–8 Fluoroacetic acid, sodium salt P198 23422–53–9 Formetanate hydrochloride. P197 17702–57–7 Formparanate. P065 628–86–4 Fulminic acid, mercury(2+) salt (R,T) P059 76–44–8 Heptachlor P062 757–58–4 Hexaethyl tetraphosphate 13a-33 Updated March 2017

P116 79–19–6 Hydrazinecarbothioamide P068 60–34–4 Hydrazine, methyl- P063 74–90–8 Hydrocyanic acid P063 74–90–8 Hydrogen cyanide P096 7803–51–2 Hydrogen phosphide P060 465–73–6 Isodrin P192 119–38–0 Isolan. P202 64–00–6 3-Isopropylphenyl N-methylcarbamate. P007 2763–96–4 3(2H)-Isoxazolone, 5-(aminomethyl)- P196 15339–36–3 Manganese, bis(dimethylcarbamodithioato- S,S -, ) P196 15339–36–3 Manganese dimethyldithiocarbamate. P092 62–38–4 Mercury, (acetato-O)phenyl- P065 628–86–4 Mercury fulminate (R,T) P082 62–75–9 Methanamine, N-methyl-N-nitroso- P064 624–83–9 Methane, isocyanato- P016 542–88–1 Methane, oxybis[chloro- P112 509–14–8 Methane, tetranitro- (R) P118 75–70–7 Methanethiol, trichloro- P198 23422–53–9 Methanimidamide, N,N-dimethyl-N -[3- [[(methylamino)- carbonyl]oxy]phenyl]-, monohydrochloride. P197 17702–57–7 Methanimidamide, N,N-dimethyl-N -[2- methyl-4- [[(methylamino)carbonyl]oxy]phenyl]- P050 115–29–7 6,9- P050 115–29–7 6,9-Methano-2,4,3- benzodioxathiepin, 6,7,8,9,10,10-hexachloro- 1,5,5a,6,9,9a- P059 76–44–8 4,7-Methano-1H-indene, 1,4,5,6,7,8,8 - heptachloro-3a,4,7,7a- tetrahydro P199 2032–65–7 Methiocarb. P066 16752–77–5 Methomyl P068 60–34–4 Methyl hydrazine P064 624–83–9 Methyl isocyanate P069 75–86–5 2-Methyllactonitrile P071 298–00–0 Methyl parathion P190 1129–41–5 Metolcarb P128 315–8–4 Mexacarbate P072 86–88–4 alpha-Naphthylthiourea

13a-34 Updated March 2017

P073 13463–39–3 Nickel carbonyl P073 13463–39–3 Nickel carbonyl Ni(CO)4, (T-4)- P074 557–19–7 Nickel cyanide P074 557–19–7 Nickel cynaide Ni(CN)2 P075 54–11–5 Nicotine, & salts P076 10102–43–9 Nitric oxide P077 100–01–6 p-Nitroaniline P078 10102–44–0 Nitrogen dioxide P076 10102–43–9 Nitrogen oxide NO P078 10102–44–0 Nitrogen oxide NO2 P081 55–63–0 Nitroglycerine (R) P082 62–75–9 N-Nitrosodimethylamine P084 4549–40–0 N-Nitrosomethylvinylamine P085 152–16–9 Octamethylpyrophosphoramide P087 20816–12–0 Osmium oxide OsO4, (T-4)- P087 20816–12–0 Osmium tetroxide P088 145–73–3 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid P194 23135–22–0 Oxamyl. P089 56–38–2 Parathion P034 131–89–5 Phenol, 2-cyclohexyl-4,6-dinitro- P048 51–28–5 Phenol, 2,4-dinitro- P047 534–52–1 Phenol, 2-methyl-4,6-dinitro-, & salts P020 88–85–7 Phenol, 2-(1-methylpropyl)-4,6-dinitro- P009 131–74–8 Phenol, 2,4,6-trinitro-, ammonium salt (R) P128 315–18–4 Phenol, 4-(dimethylamino)-3,5-dimethyl-, methylcarbamate (ester) P199 2032–65–7 Phenol, (3,5-dimethyl-4-(methylthio)-, methylcarbamate P202 64–00–6 Phenol, 3-(1-methylethyl)-, methyl carbamate P201 2631–37–0 Phenol, 3-methyl-5-(1-methylethyl)-, methyl carbamate P092 62–38–4 Phenylmercury acetate P093 103–85–5 Phenylthiourea P094 298–02–2 Phorate P095 75–44–5 Phosgene P096 7803–51–2 Phosphine

13a-35 Updated March 2017

P041 311–45–5 Phosphoric acid, diethyl 4-nitrophenyl ester P039 298–04–4 Phosphorodithioic acid, O,O-diethyl S-[2- (ethylthio)ethyl]ester P094 298–02–2 Phosphorodithioic acid, O,O-diethyl S-[ethylthio)methyl]ester P044 60–51–5 Phosphorodithioic acid, O,O-dimethyl S-[2- (methylamino)-2- oxoethyl] ester P043 55–91–4 Phosphorofluoridic acid, bis(1-methylethyl) ester P089 56–38–2 Phosphorothioic acid, O,O-diethyl O-(4- nitrophenyl) ester P040 297–97–2 Phosphorothioic acid, O,O-diethyl O-pyrazinyl ester P097 52–85–7 Phosphorothioic acid,O-[4- [(dimethylamino)sulfonyl]phenyl] O,O- dimethyl ester P071 298–00–0 Phosphorothioic acid, O,O,-dimethyl O-(4- nitrophenyl) ester P204 57–47–6 Physostigmine. P188 57–64–7 Physostigmine salicylate P110 78–00–2 Plumbane, tetraethyl- P098 151–50–8 Potassium cyanide P098 151–50–8 Potassium cyanide K(CN) P099 506–61–6 Potassium silver cyanide P201 2631–37–0 Promecarb P070 116–06–3 Propanal, 2-methyl-2-(methylthio)-,O- [(methylamino)carbonyl]oxime P203 1646–88–4 Propanal, 2-methyl-2-(methyl-sulfonyl)-, O- [(methylamino)carbonyl] oxime P101 107–12–0 Propanenitrile P027 542–76–7 Propanenitrile, 3-chloro- P069 75–86–5 Propanenitrile, 2-hydroxy-2-methyl- P081 55–63–0 1,2,3-Propanetriol, trinitrate (R) P017 598–31–2 2-Propanone, 1-bromo- P102 107–19–7 Propargyl alcohol P003 107–02–8 2-Propenal P005 107–18–6 2-Propen-1-ol P067 75–55–8 1,2-Propylenimine P102 107–19–7 2-Propyn-1-ol P008 504–24–5 4-Pyridinamine P075 54–11–5 Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S)-, & salts P204 57–47–6 Pyrrolo[2,3-b]indol-5-ol, 1,2,3,3a,8,8a- hexahydro-1,3a,8- trimethyl-,methylcarbamate (ester), (3aS-cis)-

13a-36 Updated March 2017

P114 12039–52–0 Selenious acid, dithallium(1+) salt P103 630–10–4 Selenourea P104 506–64–9 Silver cyanide P104 506–64–9 Silver cyanide Ag(CN) P105 26628–22–8 Sodium azide P106 143–33–9 Sodium cyanide P106 143–33–9 Sodium cyanide Na(CN) P108 57–24–9 Strychnidin-10-one, & salts P018 357–57–3 Strychnidin-10-one, 2,3-dimethoxy- P108 57–24–9 Strychnine, & salts P115 7446–18–6 Sulfuric acid, dithallium(1+) salt P109 3689–24–5 Tetraethyldithiopyrophosphate P110 78–00–2 Tetraethyl lead P111 107–49–3 Tetraethyl pyrophosphate P112 509–14–8 Tetranitromethane (R) P062 757–58–4 Tetraphosphoric acid, hexaethyl ester P113 1314–32–5 Thallic oxide P113 1314–32–5 Thallium oxide Tl2O3 P114 12039–52–0 Thallium(I) selenite P115 7446–18–6 Thallium(I) sulfate P109 3689–24–5 Thiodiphosphoric acid, tetraethyl ester P045 39196–18–4 Thiofanox P049 541–53–7 Thioimidodicarbonic diamide [(H2N)C(S)]2NH P014 108–98–5 Thiophenol P116 79–19–6 Thiosemicarbazide P026 5344–82–1 Thiourea, (2-chlorophenyl)- P072 86–88–4 Thiourea, 1-naphthalenyl- P093 103–85–5 Thiourea, phenyl- P185 26419–73–8 Tirpate P123 8001–35–2 Toxaphene P118 75–70–7 Trichloromethanethiol P119 7803–55–6 Vanadic acid, ammonium salt P120 1314–62–1 Vanadium oxide V2O5 P120 1314–62–1 Vanadium pentoxide

13a-37 Updated March 2017

P084 4549–40–0 Vinylamine, N-methyl-N-nitroso- P001 81–81–2 Warfarin, & salts, when present at concentrations greater than 0.3% P205 137–30–4 Zinc, bis(dimethylcarbamodithioato-S,S -, ) P121 557–21–1 Zinc cyanide P121 557–21–1 Zinc cyanide Zn(CN)2 P122 1314–84–7 Zinc phosphide Zn3P2, when present at concentrations greater than 10% (R,T) P205 137–30–4 Ziram. U394 30558–43–1 A2213 U001 75–07–0 Acetaldehyde (I) U034 75–87–6 Acetaldehyde, trichloro- U187 62–44–2 Acetamide, N-(4-ethoxyphenyl)- U005 53–96–3 Acetamide, N-9H-fluoren-2-yl- U240 94–75–7 Acetic acid, (2,4-dichlorophenoxy)-, salts & esters U112 141–78–6 Acetic acid ethyl ester (I) U144 301–04–2 Acetic acid, lead(2+) salt U214 563–68–8 Acetic acid, thallium(1+) salt see 93-76-5 Acetic Acid, (2,4,5-trichlorophenoxy)- F027 U002 67–64–1 Acetone (I) U003 75–05–8 Acetonitrile (I,T) U004 98–86–2 Acetophenone U005 53–96–3 2-Acetylaminofluorene U006 75–36–5 Acetyl chloride (C,R,T) U007 79–06–1 Acrylamide U008 79–10–7 Acrylic acid (I) U009 107–13–1 Acrylonitrile U011 61–82–5 Amitrole U012 62–53–3 Aniline (I,T) U136 75–60–5 Arsinic acid, dimethyl- U014 492–80–8 Auramine U015 115–02–6 Azaserine U365 2212–67–1 H-Azepine-1-carbothioic acid, hexahydro-, S- ethyl ester. U010 50–07–7 Azirino[2 -a]indole,3:3,4]pyrrolo[1,2-4,7- dione, 6-amino-8- [[(aminocarbonyl)oxy]methyl]-

13a-38 Updated March 2017

U280 101–27–9 Barban U278 22781–23–3 Bendiocarb U364 22961–82–6 Bendiocarb phenol U271 17804–35–2 Benomyl U157 56–49–5 Benz[j]aceanthrylene, 1,2-dihydro-3-methyl- U016 225–51–4 Benz[c]acridine U017 98–87–3 Benzal chloride U192 23950–58–5 Benzamide, 3,5-dichloro-N-(1,1-dimethyl-2- propynyl)- U018 56–55–3 Benz[a]anthracene U094 57–97–6 Benz[a]anthracene, 7,12-dimethyl- U012 62–53–3 Benzenamine (I,T) U014 492–80–8 Benzenamine, 4,4 -carbonimidoylbis[N,N- dimethyl- U049 3165–93–3 Benzenamine, 4-chloro-2-methyl-, hydrochloride U093 60–11–7 Benzenamine, N,N-dimethyl-4-(phenylazo)- U328 95–53–4 Benzenamine, 2-methyl- U353 106–49–0 Benzenamine, 4-methyl- U158 101–14–4 Benzenamine, 4,4 -methylenebis[2-chloro- U222 636–21–5 Benzenamine, 2-methyl-, hydrochloride U181 99–55–8 Benzenamine, 2-methyl-5-nitro- U019 71–43–2 Benzene (I,T) U038 510–15–6 Benzeneacetic acid, 4-chloro-alpha-(4- chlorophenyl)-alpha- hydroxy-, ethyl ester U030 101–55–3 Benzene, 1-bromo-4-phenoxy- U035 305–03–3 Benzenebutanoic acid, 4-[bis(2- chloroethyl)amino]- U037 108–90–7 Benzene, chloro- U221 25376–45–8 Benzenediamine, ar-methyl- U028 117–81–7 1,2-Benzenedicarboxylic acid, bis(2- ethylhexyl) ester U069 84–74–2 1,2-Benzenedicarboxylic acid, dibutyl ester U088 84–66–2 1,2-Benzenedicarboxylic acid, diethyl ester U102 131–11–3 1,2-Benzenedicarboxylic acid, dimethyl ester U107 117–84–0 1,2-Benzenedicarboxylic acid, dioctyl ester U070 95–50–1 Benzene, 1,2-dichloro- U071 541–73–1 Benzene, 1,3-dichloro- U072 106–46–7 Benzene, 1,4-dichloro- U060 72–54–8 Benzene, 1,1 -(2,2-dichloroethylidene)bis[4- chloro- 13a-39 Updated March 2017

U017 98–87–3 Benzene, (dichloromethyl)- U223 26471–62–5 Benzene, 1,3-diisocyanatomethyl- (R,T) U239 1330–20–7 Benzene, dimethyl- (I,T) U201 108–46–3 1,3-Benzenediol U127 118–74–1 Benzene, hexachloro- U056 110–82–7 Benzene, hexahydro- (I) U220 108–88–3 Benzene, methyl- U105 121–14–2 Benzene, 1-methyl-2,4-dinitro- U106 606–20–2 Benzene, 2-methyl-1,3-dinitro- U055 98–82–8 Benzene, (1-methylethyl)- (I) U169 98–95–3 Benzene, nitro- U183 608–93–5 Benzene, pentachloro- U185 82–68–8 Benzene, pentachloronitro- U020 98–09–9 Benzenesulfonic acid chloride (C,R) U020 98–09–9 Benzenesulfonyl chloride (C,R) U207 95–94–3 Benzene, 1,2,4,5-tetrachloro- U061 50–29–3 Benzene, 1,1 -(2,2,2-trichloroethylidene)bis[4- chloro- U247 72–43–5 Benzene, 1,1-(2,2,2-trichloroethylidene)bis[4- methoxy- U023 98–07–7 Benzene, (trichloromethyl)- U234 99–35–4 Benzene, 1,3,5-trinitro- U021 92–87–5 Benzidine U202 81–07–2 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide, & salts U278 22781–23–3 1,3-Benzodioxol-4-ol, 2,2-dimethyl-, methyl carbamate U364 22961–82–6 1,3-Benzodioxol-4-ol, 2,2-dimethyl-, U203 94–59–7 1,3-Benzodioxole, 5-(2-propenyl)- U141 120–58–1 1,3-Benzodioxole, 5-(1-propenyl)- U367 1563–38–8 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl- U090 94–58–6 1,3-Benzodioxole, 5-propyl- U064 189–55–9 Benzo[rst]pentaphene U248 181–81–2 2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo- 1-phenyl-butyl)-, & salts, when present at concentrations of 0.3% or U022 50–32–8 Benzo[a]pyrene U197 106–51–4 p-Benzoquinone U023 98–07–7 Benzotrichloride (C,R,T) U085 1464–53–5 2,2 -Bioxirane

13a-40 Updated March 2017

U021 92–87–5 [1,1 -Biphenyl]-4,4 -diamine U073 91–94–1 [1,1 -Biphenyl]-4,4 -diamine, 3,3 -dichloro- U091 119–90–4 [1,1 -Biphenyl]-4,4 -diamine, 3,3 -dimethoxy- U095 119–93–7 [1,1-Biphenyl]-4,4 -diamine, 3,3 -dimethyl- U401 97–74–5 Bis(dimethylthiocarbamoyl) sulfide. U400 120–54–7 Bis(pentamethylene)thiuram tetrasulfide. U225 75–25–2 Bromoform U030 101–55–3 4-Bromophenyl phenyl ether U128 87–68–3 1,3-Butadiene, 1,1,2,3,4,4-hexachloro- U172 924–16–3 1-Butanamine, N-butyl-N-nitroso- U031 71–36–3 1-Butanol (I) U159 78–93–3 2-Butanone (I,T) U160 1338–23–4 2-Butanone, peroxide (R,T) U053 4170–30–3 2-Butenal U074 764–41–0 2-Butene, 1,4-dichloro- (I,T) U143 303–34–4 2-Butenoic acid, 2-methyl-, 7-[[2,3-dihydroxy- 2-(1- methoxyethyl)-3-methyl-1- oxobutoxy]methyl]- U031 71–36–3 n-Butyl alcohol (I) U392 2008–41–5 Butylate. U136 75–60–5 Cacodylic acid U032 13765–19–0 Calcium chromate U372 10605–21–7 Carbamic acid, 1H-benzimidazol-2-yl, methyl ester U271 17804–35–2 Carbamic acid, [1-[(butylamino)carbonyl]-1H- benzimidazol-2- yl]-, methyl ester. U375 55406–53–6 Carbamic acid, butyl-, 3-iodo-2-propynyl ester U280 101–27–9 Carbamic acid, (3-chlorophenyl)-, 4-chloro-2- butynyl ester U238 51–79–6 Carbamic acid, ethyl ester U178 615–53–2 Carbamic acid, methylnitroso-, ethyl ester U373 122–42–9 Carbamic acid, phenyl-, 1-methylethyl ester U409 23564–05–8 Carbamic acid, [1,2-phenylenebis (iminocarbonothioyl)]bis-, dimethyl ester U097 79–44–7 Carbamic chloride, dimethyl- U379 136–30–1 Carbamodithioic acid, dibutyl, sodium salt. U277 95–06–7 Carbamodithioic acid, diethyl-, 2-chloro-2- propenyl ester U381 148–18–5 Carbamodithioic acid, diethyl-, sodium salt. U383 128–03–0 Carbamodithioic acid, dimethyl, potassium salt

13a-41 Updated March 2017

U382 128–04–1 Carbamodithioic acid, dimethyl-, sodium salt. U376 144–34–3 Carbamodithioic acid, dimethyl-, tetraanhydrosulfide with orthothioselenious acid U378 51026–28–9 Carbamodithioic acid, (hydroxymethyl)methyl- , monopotassium salt U384 137–42–8 Carbamodithioic acid, methyl-, monosodium salt U377 137–41–7 Carbamodithioic acid, methyl,- monopotassium salt U389 2303–17–5 Carbamothioic acid, bis(1-methylethyl)-, S- (2,3,3-trichloro-2- propenyl) ester U392 2008–41–5 Carbamothioic acid, bis(2-methylpropyl)-, S- ethyl ester U391 1114–71–2 Carbamothioic acid, butylethyl-, S-propyl ester U386 1134–23–2 Carbamothioic acid, cyclohexylethyl-, S-ethyl ester U390 759–94–4 Carbamothioic acid, dipropyl-, S-ethyl ester U387 52888–80–9 Carbamothioic acid, dipropyl-, S- (phenylmethyl) ester U385 1929–77–7 Carbamothioic acid, dipropyl-, S-propyl ester U114 111–54–6 Carbamodithioic acid, 1,2-ethanediylbis-, salts & esters U062 2303–16–4 Carbamothioic acid, bis(1-methylethyl)-, S- (2,3-dichloro-2- propenyl) ester U279 63–25–2 Carbaryl U372 10605–21–7 Carbendazim U367 1563–38–8 Carbofuran phenol U215 6533–73–9 Carbonic acid, dithallium(1+) salt U033 353–50–4 Carbonic difluoride U156 79–22–1 Carbonochloridic acid, methyl ester (I,T)

13a-42 Updated March 2017

U047 91–58–7 beta-Chloronaphthalene U048 95–57–8 o-Chlorophenol U049 3165–93–3 4-Chloro-o-toluidine, hydrochloride U032 13765–19–0 Chromic acid H2CrO4, calcium salt U050 218–01–9 Chrysene U393 137–29–1 Copper, bis(dimethylcarbamodithioato-S,S’)-, U393 137–29–1 Copper dimethyldithiocarbamate. U051 Creosote U052 1319–77–3 Cresol (Cresylic acid) U053 4170–30–3 Crotonaldehyde U055 98–82–8 Cumene (I) U246 506–68–3 Cyanogen bromide (CN)Br U386 1134–23–2 Cycloate. U197 106–51–4 2,5-Cyclohexadiene-1,4-dione U056 110–82–7 Cyclohexane (I) U129 58–89–9 Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3beta,4alpha,5alpha,6beta)- U057 108–94–1 Cyclohexanone (I) U130 77–47–4 1,3-Cyclopentadiene, 1,2,3,4,5,5-hexachloro- U058 50–18–0 Cyclophosphamide U240 94–75–7 2,4-D, salts & esters U059 20830–81–3 Daunomycin U366 533–74–4 Dazomet. U060 72–54–8 DDD U061 50–29–3 DDT U062 2303–16–4 Diallate U063 53–70–3 Dibenz[a,h]anthracene U064 189–55–9 Dibenzo[a,i]pyrene U066 96–12–8 1,2-Dibromo-3-chloropropane U069 84–74–2 Dibutyl phthalate U070 95–50–1 o-Dichlorobenzene U071 541–73–1 m-Dichlorobenzene U072 106–46–7 p-Dichlorobenzene U073 91–94–1 3,3 -Dichlorobenzidine

13a-43 Updated March 2017

U074) 764–41–0 1,4-Dichloro-2-butene (I,T) U075 75–71–8 Dichlorodifluoromethane U078 75–35–4 1,1-Dichloroethylene U079 156–60–5 1,2-Dichloroethylene U025 111–44–4 Dichloroethyl ether U027 108–60–1 Dichloroisopropyl ether U024 111–91–1 Dichloromethoxy ethane U081 120–83–2 2,4-Dichlorophenol U082 87–65–0 2,6-Dichlorophenol U084 542–75–6 1,3-Dichloropropene U085 1464–53–5 1,2:3,4-Diepoxybutane (I,T) U108 123–91–1 1,4-Diethyleneoxide U028 117–81–7 Diethylhexyl phthalate U395 5952–26–1 Diethylene glycol, dicarbamate U086 1615–80–1 N,N -Diethylhydrazine U087 3288–58–2 O,O-Diethyl S-methyl dithiophosphate U088 84–66–2 Diethyl phthalate U089 56–53–1 Diethylstilbesterol U090 94–58–6 Dihydrosafrole U091 119–90–4 3,3 -Dimethoxybenzidine U092 124–40–3 Dimethylamine (I) U093 60–11–7 p-Dimethylaminoazobenzene U094 57–97–6 7,12-Dimethylbenz[a]anthracene U095 119–93–7 3,3 -Dimethylbenzidine U096 80–15–9 alpha,alpha-Dimethylbenzylhydroperoxide (R) U097 79–44–7 Dimethylcarbamoyl chloride U098 57–14–7 1,1-Dimethylhydrazine U099 540–73–8 1,2-Dimethylhydrazine U101 105–67–9 2,4-Dimethylphenol U102 131–11–3 Dimethyl phthalate U103 77–78–1 Dimethyl sulfate U105 121–14–2 2,4-Dinitrotoluene U106 606–20–2 2,6-Dinitrotoluene U107 117–84–0 Di-n-octyl phthalate

13a-44 Updated March 2017

U108 123–91–1 1,4-Dioxane U109 122–66–7 1,2-Diphenylhydrazine U110 142–84–7 Dipropylamine (I) U111 621–64–7 Di-n-propylnitrosamine U403. 97–77–8 Disulfiram. U390 759–94–4 EPTC. U041 106–89–8 Epichlorohydrin U001 75–07–0 Ethanal (I) U404 121–44–8 Ethanamine, N,N-diethyl- U174 55–18–5 Ethanamine, N-ethyl-N-nitroso- U155 91–80–5 1,2-Ethanediamine, N,N-dimethyl-N -2- pyridinyl-N -(2- thienylmethyl)- U067 106–93–4 Ethane, 1,2-dibromo- U076 75–34–3 Ethane, 1,1-dichloro- U077 107–06–2 Ethane, 1,2-dichloro- U131 67–72–1 Ethane, hexachloro- U024 111–91–1 Ethane, 1,1 -[methylenebis(oxy)]bis[2-chloro- U117 60–29–7 Ethane, 1,1 -oxybis-(I) U025 111–44–4 Ethane, 1,1 -oxybis[2-chloro- U184 76–01–7 Ethane, pentachloro- U208 630–20–6 Ethane, 1,1,1,2-tetrachloro- U209 79–34–5 Ethane, 1,1,2,2-tetrachloro- U218 62–55–5 Ethanethioamide U226 71–55–6 Ethane, 1,1,1-trichloro- U227 79–00–5 Ethane, 1,1,2-trichloro- U410 59669–26–0 Ethanimidothioic acid, N,N’- [thiobis[(methylimino)carbonyloxy]]bis-, dimethyl U394 30558–43–1 Ethanimidothioic acid, 2-(dimethylamino)-N- hydroxy-2-oxo-, methyl ester. U359 110–80–5 Ethanol, 2-ethoxy- U173 1116–54–7 Ethanol, 2,2 -(nitrosoimino)bis- U395 5952–26–1 Ethanol, 2,2 -oxybis-, dicarbamate. U004 98–86–2 Ethanone, 1-phenyl- U043 75–01–4 Ethene, chloro- U042 110–75–8 Ethene, (2-chloroethoxy)- U078 75–35–4 Ethene, 1,1-dichloro-

13a-45 Updated March 2017

U079 156–60–5 Ethene, 1,2-dichloro-, (E)- U210 127–18–4 Ethene, tetrachloro- U228 79–01–6 Ethene, trichloro- U112 141–78–6 Ethyl acetate (I) U113 140–88–5 Ethyl acrylate (I) U238 51–79–6 Ethyl carbamate (urethane) U117 60–29–7 Ethyl ether (I) U114 111–54–6 Ethylenebisdithiocarbamic acid, salts & esters U067 106–93–4 Ethylene dibromide U077 107–06–2 Ethylene dichloride U359 110–80–5 Ethylene glycol monoethyl ether U115 75–21–8 Ethylene oxide (I,T) U116 96–45–7 Ethylenethiourea U076 75–34–3 Ethylidene dichloride U118 97–63–2 Ethyl methacrylate U119 62–50–0 Ethyl methanesulfonate U407 14324–55–1 Ethyl Ziram U396 14484–64–1 Ferbam U120 206–44–0 Fluoranthene U122 50–00–0 Formaldehyde U123 64–18–6 Formic acid (C,T) U124 110–00–9 Furan (I) U125 98–01–1 2-Furancarboxaldehyde (I) U147 108–31–6 2,5-Furandione U213 109–99–9 Furan, tetrahydro-(I) U125 98–01–1 Furfural (I) U124 110–00–9 Furfuran (I) U206 18883–66–4 Glucopyranose, 2-deoxy-2-(3-methyl-3- nitrosoureido)-, DU20 18883–66–4 D-Glucose, 2-deoxy-2-[[(methylnitrosoamino)- carbonyl]amino]- 6 U126 765–34–4 Glycidylaldehyde U163 70–25–7 Guanidine, N-methyl-N -nitro-N-nitroso- U127 118–74–1 Hexachlorobenzene U128 87–68–3 Hexachlorobutadiene U130 77–47–4 Hexachlorocyclopentadiene

13a-46 Updated March 2017

U131 67–72–1 Hexachloroethane U132 70–30–4 Hexachlorophene U243 1888–71–7 Hexachloropropene U133 302–01–2 Hydrazine (R,T) U086 1615–80–1 Hydrazine, 1,2-diethyl- U098 57–14–7 Hydrazine, 1,1-dimethyl- U099 540–73–8 Hydrazine, 1,2-dimethyl- U109 122–66–7 Hydrazine, 1,2-diphenyl- U134 7664–39–3 Hydrofluoric acid (C,T) U134 7664–39–3 Hydrogen fluoride (C,T) U135 7783–06–4 Hydrogen sulfide U135 7783–06–4 Hydrogen sulfide H2S U096 80–15–9 Hydroperoxide, 1-methyl-1-phenylethyl- (R) U116 96–45–7 2-Imidazolidinethione U137 193–39–5 Indeno[1,2,3-cd]pyrene U375 55406–53–6 3-Iodo-2-propynyl n-butylcarbamate U396 14484–64–1 Iron, tris(dimethylcarbamodithioato-S,S -, ) U190 85–44–9 1,3-Isobenzofurandione U140 78–83–1 Isobutyl alcohol (I,T) U141 120–58–1 Isosafrole U142 143–50–0 Kepone U143 303–34–4 Lasiocarpine U144 301–04–2 Lead acetate U146 1335–32–6 Lead, bis(acetato-O)tetrahydroxytri- U145 7446–27–7 Lead phosphate U146 1335–32–6 Lead subacetate U129 58–89–9 Lindane U163 70–25–7 MNNG U147 108–31–6 Maleic anhydride U148 123–33–1 Maleic hydrazide U149 109–77–3 Malononitrile U150 148–82–3 Melphalan U151 7439–97–6 Mercury U384 137–42–8 Metam Sodium. U152 126–98–7 Methacrylonitrile (I, T) 13a-47 Updated March 2017

U092 124–40–3 Methanamine, N-methyl- (I) U029 74–83–9 Methane, bromo- U045 74–87–3 Methane, chloro- (I, T) U046 107–30–2 Methane, chloromethoxy- U068 74–95–3 Methane, dibromo- U080 75–09–2 Methane, dichloro- U075 75–71–8 Methane, dichlorodifluoro- U138 74–88–4 Methane, iodo- U119 62–50–0 Methanesulfonic acid, ethyl ester U211 56–23–5 Methane, tetrachloro- U153 74–93–1 Methanethiol (I, T) U225 75–25–2 Methane, tribromo- U044 67–66–3 Methane, trichloro- U121 75–69–4 Methane, trichlorofluoro- U036 57–74–9 4,7-Methano-1H-indene, 1,2,4,5,6,7,8,8- octachloro-2,3,3a,4,7,7a- hexahydro- U154 67–56–1 Methanol (I) U155 91–80–5 Methapyrilene U142 143–50–0 1,3,4-Metheno-2H-cyclobuta[cd]pentalen-2- one, 1,1a,3,3a,4,5,5,5a,5b,6- U247 72–43–5 Methoxychlor U154 67–56–1 Methyl alcohol (I) U029 74–83–9 Methyl bromide U186 504–60–9 1-Methylbutadiene (I) U045 74–87–3 Methyl chloride (I,T) U156 79–22–1 Methyl chlorocarbonate (I,T) U226 71–55–6 Methyl chloroform U157 56–49–5 3-Methylcholanthrene U158 101–14–4 4,4 -Methylenebis(2-chloroaniline) U068 74–95–3 Methylene bromide U080 75–09–2 Methylene chloride U159 78–93–3 Methyl ethyl ketone (MEK) (I,T) U160 1338–23–4 Methyl ethyl ketone peroxide (R,T) U138 74–88–4 Methyl iodide U161 108–10–1 Methyl isobutyl ketone (I)

13a-48 Updated March 2017

U162 80–62–6 Methyl methacrylate (I,T) U161 108–10–1 4-Methyl-2-pentanone (I) U164 56–04–2 Methylthiouracil U010 50–07–7 Mitomycin C U365 2212–67–1 Molinate U059 20830–81–3 5,12-Naphthacenedione, 8-acetyl-10-[(3- amino-2,3,6-trideoxy)- alpha-L-lyxo- hexopyranosyl)oxy]-7,8,9,10- U167 134–32–7 1-Naphthalenamine U168 91–59–8 2-Naphthalenamine U026 494–03–1 Naphthalenamine, N,N -bis(2-chloroethyl)- U165 91–20–3 Naphthalene U047 91–58–7 Naphthalene, 2-chloro- U166 130–15–4 1,4-Naphthalenedione U236 72–57–1 2,7-Naphthalenedisulfonic acid, 3,3 -[(3,3 - dimethyl[1,1’- biphenyl]-4,4’-diyl)bis(azo)bis[5- amino-4- U279 63–25–2 1-Naphthalenol, methylcarbamate U166 130–15–4 1,4-Naphthoquinone U167 134–32–7 alpha-Naphthylamine U168 91–59–8 beta-Naphthylamine U217 10102–45–1 Nitric acid, thallium(1+) salt U169 98–95–3 Nitrobenzene (I,T) U170 100–02–7 p-Nitrophenol U171 79–46–9 2-Nitropropane (I,T) U172 924–16–3 N-Nitrosodi-n-butylamine U173 1116–54–7 N-Nitrosodiethanolamine U174 55–18–5 N-Nitrosodiethylamine U176 759–73–9 N-Nitroso-N-ethylurea U177 684–93–5 N-Nitroso-N-methylurea U178 615–53–2 N-Nitroso-N-methylurethane U179 100–75–4 N-Nitrosopiperidine U180 930–55–2 N-Nitrosopyrrolidine U181 99–55–8 5-Nitro-o-toluidine U193 1120–71–4 1,2-Oxathiolane, 2,2-dioxide U058 50–18–0 2H-1,3,2-Oxazaphosphorin-2-amine,N,N- bis(2- chloroethyl)tetrahydro-, 2-oxide U115 75–21–8 Oxirane (I,T) 13a-49 Updated March 2017

U126 765–34–4 Oxiranecarboxyaldehyde U041 106–89–8 Oxirane, (chloromethyl)- 2 123–63–7 Paraldehyde U391 1114–71–2 Pebulate. U183 608–93–5 Pentachlorobenzene U184 76–01–7 Pentachloroethane U185 82–68–8 Pentachloronitrobenzene (PCNB) See 87–86–5 Pentachlorophenol F027 U161 108–10–1 Pentanol, 4-methyl- U186 504–60–9 1,3-Pentadiene (I) U187 62–44–2 Phenacetin U188 108–95–2 Phenol U048 95–57–8 Phenol, 2-chloro- U039 59–50–7 Phenol, 4-chloro-3-methyl- U081 120–83–2 Phenol, 2,4-dichloro- U082 87–65–0 Phenol, 2,6-dichloro- U089 56–53–1 Phenol, 4,4 -(1,2-diethyl-1,2-ethenediyl)bis-, (E)- U101 105–67–9 Phenol, 2,4-dimethyl- U052 1319–77–3 Phenol, methyl- U132 70–30–4 Phenol, 2,2 -methylenebis[3,4,6-trichloro- U411 114–26–1. Phenol, 2-(1-methylethoxy)-, methylcarbamate.

U170 100–02–7 Phenol, 4-nitro- See 87–86–5 Phenol, pentachloro- F027 See 58–90–2 Phenol, 2,3,4,6-tetrachloro- F027 See 95-95-4 Phenol, 2,4,5-trichloro- F027 See 88–06–2 Phenol, 2,4,6-trichloro- F027 U150 148–82–3 L-Phenylalanine, 4-[bis(2-chloroethyl)amino]- U145 7446–27–7 Phosphoric acid, lead(2+) salt (2:3) U087 3288–58–2 Phosphorodithioic acid, O,O-diethyl S-methyl ester U189 1314–80–3 Phosphorus sulfide (R) U190 85–44–9 Phthalic anhydride

13a-50 Updated March 2017

U191 109–06–8 2-Picoline U179 100–75–4 Piperidine, 1-nitroso- U400 120–54–7 Piperidine, 1,1 -(tetrathiodicarbonothioyl)-bis- U383 128–03–0 Potassium dimethyldithiocarbamate U378 51026–28–9 Potassium n-hydroxymethyl- n-methyldithiocarbamate U377 137–41–7 Potassium n-methyldithiocarbamate U192 23950–58–5 Pronamide U194 107–10–8 1-Propanamine (I,T) U111 621–64–7 1-Propanamine, N-nitroso-N-propyl- U110 142–84–7 1-Propanamine, N-propyl- (I) U066 96–12–8 Propane, 1,2-dibromo-3-chloro- U083 78–87–5 Propane, 1,2-dichloro- U149 109–77–3 Propanedinitrile U171 79–46–9 Propane, 2-nitro- (I,T) U027 108–60–1 Propane, 2,2 -oxybis[2-chloro- U193 1120–71–4 1,3-Propane sultone See 93–72–1 Propanoic acid, 2-(2,4,5-trichlorophenoxy)- F027 U235 126–72–7 1-Propanol, 2,3-dibromo-, phosphate (3:1) U140 78–83–1 1-Propanol, 2-methyl- (I,T) U002 67–64–1 2-Propanone (I) U007 79–06–1 2-Propenamide U084 542–75–6 1-Propene, 1,3-dichloro- U243 1888–71–7 1-Propene, 1,1,2,3,3,3-hexachloro- U009 107–13–1 2-Propenenitrile U152 126–98–7 2-Propenenitrile, 2-methyl- (I,T) U008 79–10–7 2-Propenoic acid (I) U113 140–88–5 2-Propenoic acid, ethyl ester (I) U118 97–63–2 2-Propenoic acid, 2-methyl-, ethyl ester U162 80–62–6 2-Propenoic acid, 2-methyl-, methyl ester (I,T) U373 122–42–9 Propham U411 114–26–1 Propoxur U387 52888–80–9 Prosulfocarb U194 107–10–8 n-Propylamine (I,T)

13a-51 Updated March 2017

U083 78–87–5 Propylene dichloride U148 123–33–1 3,6-Pyridazinedione, 1,2-dihydro- U196 110–86–1 Pyridine U191 109–06–8 Pyridine, 2-methyl- U237 66–75–1 2,4-(1H,3H)-Pyrimidinedione, 5-[bis(2- chloroethyl)amino]- U164 56–04–2 4(1H)-Pyrimidinone, 2,3-dihydro-6-methyl-2- thioxo- U180 930–55–2 Pyrrolidine, 1-nitroso- U200 50–55–5 Reserpine U201 108–46–3 Resorcinol U202 81–07–2 Saccharin, & salts U203 94–59–7 Safrole U204 7783–00–8 Selenious acid U204 7783–00–8 Selenium dioxide U205 7488–56–4 Selenium sulfide U205 7488–56–4 Selenium sulfide SeS2 (R,T) U376 144–34–3 Selenium, tetrakis(dimethyldithiocarbamate) U015 115–02–6 L-Serine, diazoacetate (ester) See 93–72–1 Silvex (2,4,5-TP) F027 U379 136–30–1 Sodium dibutyldithiocarbamate. U381 148–18–5 Sodium diethyldithiocarbamate U382 128–04–1 Sodium dimethyldithiocarbamate U206 18883–66–4 Streptozotocin U103 77–78–1 Sulfuric acid, dimethyl ester U277 95–06–7 Sulfallate U189 1314–80–3 Sulfur phosphide (R) See 2,4,5-T 2,4,5-T F027 U402 1634–02–2 Tetrabutylthiuram disulfide U207 95–94–3 1,2,4,5-Tetrachlorobenzene U208 630–20–6 1,1,1,2-Tetrachloroethane U209 79–34–5 1,1,2,2-Tetrachloroethane U210 127–18–4 Tetrachloroethylene See 58–90–2 2,3,4,6-Tetrachlorophenol F027

13a-52 Updated March 2017

U213 109–99–9 Tetrahydrofuran (I) U401 97–74–5 Tetramethylthiuram monosulfide U214 563–68–8 Thallium(I) acetate U215 6533–73–9 Thallium(I) carbonate U216 7791–12–0 Thallium(I) chloride U216 7791–12–0 Thallium chloride Tlcl U217 10102–45–1 Thallium(I) nitrate U366 533–74–4 2H-1,3,5-Thiadiazine- 2-thione, tetrahydro- 3,5-dimethyl- U218 62–55–5 Thioacetamide U410 59669–26–0 Thiodicarb. U153 74–93–1 Thiomethanol (I,T) U244 137–26–8 Thioperoxydicarbonic diamide [(H2N)C(S)]2S2, tetramethyl- U402 1634–02–2 Thioperoxydicarbonic diamide, tetrabutyl U403 97–77–8 Thioperoxydicarbonic diamide, tetraethyl U409 23564–05–8 Thiophanate-methyl U219 62–56–6 Thiourea U244 137–26–8 Thiram U220 108–88–3 Toluene U221 25376–45–8 Toluenediamine U223 26471–62–5 Toluene diisocyanate (R,T) U328 95–53–4 o-Toluidine U353 106–49–0 p-Toluidine U222 636–21–5 o-Toluidine hydrochloride U389 2303–17–5 Triallate U011 61–82–5 1H-1,2,4-Triazol-3-amine U227 79–00–5 1,1,2-Trichloroethane U228 79–01–6 Trichloroethylene U121 75–69–4 Trichloromonofluoromethane See 2,4,5- 2,4,5-Trichlorophenol F027 Trichlorophenol See 88–06–2 2,4,6-Trichlorophenol F027 U404 121–44–8 Triethylamine. U234 99–35–4 1,3,5-Trinitrobenzene (R,T) U182 123–63–7 1,3,5-Trioxane, 2,4,6-trimethyl-

13a-53 Updated March 2017

U235 126–72–7 Tris(2,3-dibromopropyl) phosphate U236 72–57–1 Trypan blue U237 66–75–1 Uracil mustard U176 759–73–9 Urea, N-ethyl-N-nitroso- U177 684–93–5 Urea, N-methyl-N-nitroso- U385 1929–77–7 Vernolate U043 75–01–4 Vinyl chloride U248 81–81–2 Warfarin, & salts, when present at concentrations of 0.3% or less U239 1330–20–7 Xylene (I) U200 50–55–5 Yohimban-16-carboxylic acid, 11,17- dimethoxy-18- [(3,4,5-trimethoxybenzoyl)oxy]-,methyl ester, U407 14324–55–1 Zinc, bis(diethylcarbamodithioato-S,S’)- U249 1314–84–7 Zinc phosphide Zn3P2, when present at concentrations of 10% or less

13a-54 Updated March 2017

Appendix B: Glove Selection Chart The times listed below are average breakthrough times for each type of glove, i.e. the minimum time that it will take for a given chemical compound to break through the glove material.

Chemical Name Nitrile PVC Neoprene Butyl Comments Acetic Acid, Glacial 4.5 hr 3 hr 7 hr NR Acetone NR NR 10 min > 17 hr Acetonitrile 30 min NR 30 min > 8 hr Ammonium Hydroxide, > 8 hr 4 hr > 6 hr NR

Aniline 72 min 3 hr 35 min > 8 hr Benzene 9 min 13 min 16 min 31 min Carbon Disulfide 20 min NR NR < 4min Carbon Tetrachloride 2.5 hr 25 min 31 min NR Chloroform NR 10 min 12 min NR Chromic Acid, 50% 4 hr NR NR NR Dichloroethane 16 min NR 33 min 2 hr Dimethyl Formamide 35 min NR 10 min > 8 hr Ethanol > 8 hr 1 hr 1.5 hr NR Ethyl Ether 64 min 14 min 10 min 8 min Formaldehyde, 37% > 8 hr 80 min 2 hr 16 hr Hexane > 8 hr 29 min 39 min 4 min Hydrochloric Acid, conc. > 8 hr NR > 8 hr NR Isopropanol > 8 hr 2.5 hr 1.5 hr NR Methylene Chloride NR NR 6 min 20 min Methyl Ethyl Ketone (MEK) > 24 hr 12 min 22 min > 6 hr Nitric Acid, conc. NR NR 2 hr NR Phenol > 8 hr 2.5 hr 3 hr > 20 hr Sodium Hydroxide, 50% > 8 hr NR > 8 hr NR Sulfuric Acid, conc. NR 3 hr 3 hr NR Tetrahydrofuran NR NR NR NR use PVA Trichloroethane 90 min 52 min 27 min NR Toluene 10 min 19 min 6 min 21 min Xylene 75 min 23 min 23 min NR Key: PVA = Polyvinyl Alcohol, a special-use glove that provides good protection against many solvents, but

13a-55 Updated March 2017

dissolves in water! Therefore, it is not recommended for general laboratory use.

NR = Not Recommended

• Latex gloves do not provide adequate protection from most chemicals

• Remember that no glove is good for an indefinite period of time.

• Check gloves after each use for degradation, tears, punctures, or swelling.

• If there is any question regarding the glove's integrity, discard it.

• Wash and dry gloves thoroughly after each use. Appendix C: Chemical Storage-Incompatible Chemicals Certain hazardous chemicals should not be mixed or stored with other chemicals because a severe reaction can take place or an extremely toxic reaction product can result. The label and SDS will contain information on incompatibilities. The following table contains examples of incompatible chemicals:

CHEMICAL KEEP OUT OF CONTACT WITH Acetic Acid Chromic acid, nitric acid hydroxyl compounds, ethylene, glycol, perchloric acid, peroxides, permanganates

Acetone Concentrated nitric and sulfuric acid mixtures Acetylene Chlorine, bromine, copper, fluorine, silver, mercury Alkali Metals Water, carbon tetrachloride or other chlorinated hydrocarbons, carbon dioxide, the halogens Ammonia, anhydrous Mercury, chlorine, calcium hypochlorite, iodine, bromine, hydrofluoric acid Ammonium Nitrate Acids, metal powders, flammable liquids, chlorates, nitrites, sulfur, finely divided organic or combustible materials Aniline Nitric acid, hydrogen peroxide Arsenical materials Any reducing agent Azides Acids Bromine Same as chlorine Calcium Oxide Water Carbon (activated) Calcium hypochlorite, all oxidizing agents Carbon tetrachloride Sodium Chlorates Ammonium salts, acids, metal powders, sulfur, finely divided organic or combustible materials Chromic Acid Acetic acid, naphthalene, camphor, glycerin, turpentine, alcohol, flammable liquids in general Chlorine Ammonia, acetylene, butadiene, butane, methane, propane (or other petroleum gases), hydrogen, sodium carbide, turpentine, benzene, finely divided metals

13a-56 Updated March 2017

Chlorine Dioxide Ammonia, methane, phosphine, hydrogen sulfide Copper Acetylene, hydrogen peroxide Cumene Hydroperoxide Acids, organic or inorganic Cyanides Acids Flammable liquids Ammonium nitrate, chromic acid, hydrogen peroxide, nitric acid, sodium peroxide, halogens Hydrocarbons Fluorine, chlorine, bromine, chromic acid, sodium peroxide Hydrocyanic Acid Nitric acid, alkali Hydrofluoric Acid Ammonia, aqueous or anhydrous Hydrogen Peroxide Copper, chromium, iron, most metals or thei salts, alcohols, acetone, Hydrogen Sulfide Fuming nitric acid, oxidizing gases, acetylene, ammonia Hypochlorites Acids, activated carbon Iodine Acetylene, ammonia (aqueous or anhydrous), hydrogen Mercury Acetylene, fulminic acid, ammonia Nitrates Sulfuric acid Nitric acid (concentrated) Acetic acid, aniline, chromic acid, hydrocyanic acid, hydrogen Nitrites Acids Nitroparaffins Inorganic bases, amines Oxalic Acid Silver, mercury Oxygen Oils, grease, hydrogen; flammable liquids, solids, or gases Perchloric acid Acetic anhydride, bismuth and its alloys, alcohol, paper, wood Peroxides, organic Acids (organic or mineral), avoid friction, store cold Phosphorus (white) Air, oxygen, alkalies, reducing agents Potassium Carbon tetrachloride, carbon dioxide, water Potassium Chlorate Sulfuric and other acids Potassium Glycerine, ethlylene glycol, benzaldehyde, sulfuric acid Selenides Reducing agents Silver Acetylene, oxalic acid, tartaric acid, ammonium compounds Sodium Carbon tetrachloride, carbon dioxide, water Sodium nitrite Ammonium nitrate and other ammonium salts Sodium Peroxide Ethyl or methyl alcohol, glacial acetic acid, acetic anhydride, Sulfides Acids Sulfuric Acid Potassium chlorate, potassium perchlorate, potassium Tellurides Reducing agents

13a-57 Updated March 2017

Training Record: Lab-Specific Chemical Hygiene Plan

The following individuals have reviewed and understood the preceding Lab-specific Chemical Hygiene Plan.

Laboratory Manager: ___Handong Ma______

Name

Chief Research and Science Officer

Research Officer

Chair, Dept. of Basic Sciences

Chair, Dept. of Pharmaceutical Sciences

Division of Research Assistant

Safety Committee Member

Manager of Research Lab, Anatomical Coordinator/Director of Anatomical Donor Services and/or Anatomy Lab Coordinator

13a-58 Updated March 2017

Part 13b. Chemical Hygiene Plan - Philadelphia

Philadelphia College of Osteopathic Medicine Occupational and Environmental Safety Department

Please contact for further assistance:

Nate Pinkney Chief Occupational/Environmental Safety Officer office 215-871-6360 | fax 215-871-6359

Pamela Vu, MPH Occupational Safety Specialist office 215-871-6150 | fax 215-871-6359

All labs using chemicals are required by OSHA to have a written Chemical Hygiene Plan (CHP) in place for chemical workers. It is the responsibility of the PCOM Occupational and Environmental Safety Department to confirm that a complete Chemical Hygiene Plan is developed and implemented. It is the responsibility of each lab supervisor/PI to ensure that the completed plan is shared with all their affected workers. PCOM is committed to providing a healthy and safe work environment for their employees and students. The CHP describes the proper use and handling procedures to be followed by faculty, staff and students working with hazardous chemicals in the laboratories.

General Laboratory Information

Laboratory Locations: Evans Hall, floors 3, 4, 5, 6, and basement

Department Information

Chemical Hygiene Officer: Scott Little, PhD | Work Number: 215-871-6882 | Work Email: [email protected]

13b-1 Updated March 2017

Location(s) of Building Emergency Assembly Points:

Philadelphia Campus: In the event of an evacuation, Rowland Hall or Activities Center should follow the evacuation maps posted inside the building. Once outside, proceed directly to the 2nd level of Parking Garage. Those in Evans Hall or Levin Administration Building should follow the evacuation maps posted inside the building. Once outside, proceed directly to the Circle. Wait for further instructions.

13b-2 Updated March 2017

Emergency Information

• Evacuation procedures • In case of a fire leave the lab and go straight out of the building.

• First-aid kit • First aid kits are located in every laboratory and office of Evans Hall and every suite in Rowland Hall. They contain minor injury supplies. Whenever something is used from a first aid kit even for minor injuries it should be reported. First aid kits are checked every 3 months for supplies.

• Spill cleanup materials • Spill cleanup kits are located on every floor of Evans Hall. The kits contain the necessary supplies for oil or chemical spills. Spill cleanup kits are checked every 3 months. • Chemical spills must be promptly contained and absorbed. Therefore, a spill control center must have such items as universal pillows, disposable aprons, absorbing/neutralizing agents for acids, bases, solvents, and formaldehyde/paraformaldehyde, mercury storage containers, full-face respirator, safety goggles, and gloves. The absorbed material must be scooped up and placed into a plastic bag for regular trash disposal. Hazardous substance spills, regardless of type and amount, must be reported immediately to the PCOM Security Dispatcher by dialing 215- 871-6351 • In the case of a hazardous spill resulting from the usage of an eyewash station or safety shower, clean up spills that may have spilled onto the floor using spill cleanup materials.

• Laboratory monitors or alarms • Incubators and freezers are on alarms.

All significant injuries must be documented via the Employee Incident Report form (available on Nucleus) as soon as possible. This is necessary for potential reimbursement for personal medical costs, or Worker’s Compensation Claims.

All fires must be reported to 9-911 immediately – even if the fire is out. This is particularly true if there is use of an extinguisher (must be replaced); an injury; or property damage.

Safety Data Sheets (SDS): Per OSHA, all lab chemical users must know: a) what an SDS is, b) SDS relevance to their health and safety, c) how to readily access them.

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Labs are encouraged to maintain their own SDS for the hazardous chemicals they routinely use.

Each lab area has its own SDS book that is updated on a regular basis. The security desk also has its own SDS book in case of a fire.

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Background: Standard Operating Procedures

• Operations involving what OSHA specifically designates as Particularly Hazardous Substances (PHS), namely, “Select” Carcinogens, Highly acute toxins, Reproductive toxins

• Other “high-hazard” chemical operations

Standard Operating Procedure: Use of “Particularly Hazardous Substances”

Per OSHA, Particularly Hazardous Substances (PHS) are “Select” Carcinogens, Reproductive Toxins and Highly Acute Toxins. Web-links to definitions and lists of these materials are below.

Date of last revision to SOP: August 2013

1. Laboratory SOP

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Reproductive toxins

• (+/-)-1-Phenyl-2,3-4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrobromide • (R)-(+)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3- benzazepine hydrochloride • (RS)-(+/-)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl) methyl]-2- methoxybenzamide • (S)-(-)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl) methyl]-2- methoxybenzamide • Cacodylic Acid Sodium Salt • Chloramphenicol • DE CE CO • Diazoxide • Dimethyl Sulfoxide (DMSO) • DRI CAV • Dry Wash II • Energized 36 • Ethylenediamine Tetraacetic Acid • Glutaraldehyde • Metasyn 35 • Nifedipine • Nitrilotriacetic Acid • Odorless • Streptomycin Sulfate • Streptozotocin • Sulfuric acid • Triton 28 • Trypan Blue Stain • Viscerock

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Highly acute toxins • Acetic Acid Glacial • Acetylcholine Chloride • (+/-)-1-Phenyl-2,3-4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrobromide • (R)-(+)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3- benzazepine hydrochloride • (RS)-(+/-)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl) methyl]-2- methoxybenzamide • (S)-(-)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl) methyl]-2- methoxybenzamide • Cacodylic Acid Sodium Salt • Dimethyl Sulfoxide (DMSO) • Hydrochloric Acid • Sodium selenite • Sodium Selenite

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1. Approval Required

All individuals who have access to the lab space are required to go through a safety training program before using any of the chemicals and to observe a faculty member or research staff demonstrate their use while learning.

2. Personal Protective Equipment

It is mandatory to wear "all" PPE when working in or utilizing the BSLII areas. It is also necessary to attend the PPE training session prior to working in or utilizing these areas.

Shorts or short clothing are not acceptable laboratory work attire. Sandals and open-toed shoes are also not acceptable.

It is mandatory to wear "all" PPE when working in or utilizing BSLII areas. It is also necessary to attend the PPE training session prior to working in or utilizing these areas.

Use of PHS shall, whenever feasible, employ the following:

• Protective eyewear such as approved safety glasses, goggles or face shields. The latter should be used when handling corrosives in large quantities (e.g. > 1 gallon). Eye washes are required in all laboratories where any corrosive chemicals are used.

• Lab coats with fully fastened buttons, particularly when using PHS that are readily absorbed through the skin, or are corrosive to skin tissue.

• All respirators, other than dust masks, must be issued and approved by the Occupational and Environmental Safety Department to meet OSHA requirements (29 CFR 1910.134(c) (2) (ii)). Everyone using a respirator must go through proper training and read the appropriate safety manual sections covering respirators. Training will and must cover proper uses, maintenance and storage of all respirators which are held within a working area. Supervisors must implement a program showing that routine maintenance is done in compliance with federal standards as listed in the above CFR and the manufacture of the respirator. 13b-8 Updated March 2017

3. Personnel Practices

• Pipetting: Mechanical pipetting aids will be used for all pipetting procedures. Mouth pipetting is prohibited.

• Eating, drinking and smoking is prohibited in laboratory areas. Food may not be stored in laboratory refrigerators or cold rooms nor can it be heated in laboratory microwaves.

• Safety Equipment: Learn the location and use of fire extinguishers, fire blankets, water hoses, fire alarms, safety showers and eyewashes.

• Fume Hoods: Avoid inhaling chemical vapors and gases. Use fume hoods whenever possible. Do not store materials in fume hoods. Keep hoods clear and clean.

• Utilities: Set up experiments so that it is not necessary to reach through the assembly to turn water, gas or electricity on or off.

• Do not heat a closed system

• Use boiling chips when heating liquids to the boiling point

4. Engineering/Ventilation Controls

All fume hoods, biosafety cabinets and water system filters are checked annually for prevention, maintenance and recertification.

• Volatile, or dust/aerosol-producing PHS must be used in a fume hood, glove box, ducted biosafety cabinet, or snorkel exhaust. Use on the open bench is prohibited except when it is impractical (i.e. equipment will not fit in hood), in which case other controls (e.g. respirator) must be employed.

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5. Procedures to Maintain a Safe Environment

6. Laboratory Injuries

• Eye Exposure: If chemicals or other hazardous materials (HAZMATS) get into the eyes, use an eye wash station. Flush eyes with water for at least fifteen (15) minutes. Eyelids may have to be forcibly held open.

• Chemical Burns and Skin Absorption: For chemical burns and skin absorption of chemicals, flush affected areas with copious amounts of cool water or use the nearest safety shower.

7. Any Special Chemical Handling, Storage, Cleanup or Disposal Requirements

Nearly all chemicals are poisonous to the human body to some degree. Flammable liquids, exothermic reactions, unstable materials, toxic and corrosive materials play a large part in causing injuries. Accidents and the resultant injuries in laboratories can be severe. The suggestions below will help in preventing chemically related accidents.

a. The CHP requires that an area must be designated for working with PHS. The designated area may be the entire laboratory, an area of the lab, or a device such as a laboratory hood. At PCOM, the designated PHS work area is the entire 13b-10 Updated March 2017

laboratory, unless the supervisor specifies otherwise herein; either in general, or for a specific material or operation.

• PHS must be stored in completely-sealed containers. Although hood storage of chemicals is generally discouraged, volatile PHS can be stored in a fume hood if deemed necessary.

• Always ensure the proper labeling of containers with contents, concentration, manufacturer, handling precautions, and expiration date (especially in the case of unstable compounds).

• Never test chemicals by taste or odor. If in doubt, do not use an unlabeled chemical.

• Always keep in mind that acids are poured into water and NOT the other way around.

• Spills of PHS must be completely cleaned up. Spills that cannot be safely and completely handled by lab personnel must be reported to PCOM Plant Operations and the PCOM Occupational and Environmental Safety Department for assistance.

• Like all chemical wastes, disposal of PHS must be done through PCOM Plant Operations and the Occupational and Environmental Safety Department. No PHS, or other chemical wastes can go into the sewer system, trash or be allowed to freely evaporate. In general, well-diluted acids and bases (between pH 6 and 9) can be flushed directly down the drain with plenty of water.

• Hazardous chemicals and/or byproducts that cannot be disposed of on the premises are to be labeled and safely packaged centrally for annual pick-up usually in the winter. All departments are notified as to the date of pick-up. Prior to the removal of the chemicals, each department must submit to the assistant disposing of the chemicals a list specifying chemical or mixture name, quantity, container type, and place of storage.

• Separate storage areas should be provided for “incompatible chemicals,” which may react and create a hazardous condition. For instance, some oxidizing acids (nitric, sulfuric, perchloric), when stored together with flammable solvents, can create a fire if the bottles are broken and there is contact of the two materials. Do not store chemicals by alphabetical listing. Store by acids, bases, salts, flammables, etc.

• Store cryogenic liquids such as: dry ice, liquid nitrogen, liquid helium, and any other liquefied gases in well-ventilated areas. Do not store these liquids in walk-in cold rooms because walk-in cold rooms are poorly ventilated. For example, the sublimation of dry ice will reduce the percentage of available oxygen.

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The following definitions have been extracted from the Code of Federal Regulations, Title 49- Transportion, Parts 100 to 177.

• Nonflammable Gas: Any compressed gas other than a flammable compressed gas. Includes the inert gases (He, Ar, Ne, Kr), and nitrogen.

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• Oxidizer: A substance such as chlorate, permanganate, inorganic peroxide, nitro carbonitrate, or a nitrate, that yields oxygen readily to stimulate the combustion of organic matter.

• Irritating Material: A liquid or solid substance which upon contact with fire or when exposed to air, gives off dangerous or intensely irritating fumes.

• Infectious Substance: A viable microorganism or its toxin which causes or may cause severe, disabling or fatal disease in humans or animals.

• Radioactive Material: Any material or combination of materials, that spontaneously emits ionizing radiation and which has a specific activity greater than 0.002 microcuries per gram.

• Miscellaneous Hazardous Material: Any material that does not meet the definition of any other hazard class mentioned but may still pose a hazard during transportation of the material. This class includes: (i) Materials which have an anesthetic, irritating, noxious, toxic, or other similar property and which can cause extreme annoyance or discomfort to passengers and crew in the event of leakage during transportation. (ii) Materials (including a solid when wet with water) capable of causing significant damage to a transport vehicle or vessel from leakage during transportation. (iii) Materials which have other inherent characteristics not described above but which make them unsuitable for shipment, unless properly identified and prepared for transportation.

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Flammable Liquids

Introduction:

Definitions of Flammable and Combustible Liquids:

Flammable: Class IA Flashpoint below 73oF (23oC) and boiling point below 100oF (38oC)

Class IB Flashpoint below 73oF (23oC) and boiling point at or above 100oF (38oC)

Class IC Flashpoint at or above 73oF (23oC) and below 100oF (38oC)

Combustible:

Class II Flashpoint at or above 100oF (38oC) and below 140oF (60oC)

Class III Flashpoint at or above 140oF (60oC) Storage

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Dispensing:

• Dispensing of flammable or combustible liquids must be carried out under a fume hood or in an approved storage room.

• All drums containing flammable liquids for dispensing must be vented with approved safety bungs.

• Only drum pumps or self-closing faucets should be used.

• All drums and all equipment subject to static accumulation must be grounded.

• Dispensing should only be into approved containers, and any metal containers must be grounded to the drum.

• All ignition sources must be eliminated from the area.

• Good housekeeping standards should be maintained, and if possible, all combustible materials eliminated, particularly where flammable liquids are located.

• Portable fire extinguishing equipment must be provided such as portable dry chemical, foam, or carbon dioxide units.

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• Do not dispose flammable or combustible liquids into sinks or drains.

Disposal:

Peroxidizable Liquids

Recognition:

There are essentially 10 major structures that readily form peroxides. As determined from the literature, the first 6 have caused numerous explosions and the last 4 very few.

1. Ethers, acetyls;

2. Olefins with allylic hydrogen, chloro- and fluoro-olefins, terpenes, tetrahydronaphthalene

3. Dienes, vinyl cetylene;

4. Vinyl monomers including vinyl halides, acrylates, methacrylates, vinyl esters;

5. Alkali metals such as potassium

6. Alkali metal, alkoxides and amines such as sodamine;

7. Paraffinic and allyl aromatic hydrocarbons, particularly those with tertiary hydrogen;

8. Organometallics such as Grignard reagent;

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10. Ureas, amines, and lactams.

Purchase:

The chemicals below must be labeled as containing peroxides.

Group 1 (3 months) Group 3 (12 months)

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Methyl isobutyl ketone Methylcyclopentane Tetrahydrofuran Tetrahydronapthalene (Tetralin) Vinyl ethers

Storage:

• All peroxidizable compounds should be stored away from heat and light. Sunlight is an especially good promoter of peroxidation.

• All containers with peroxidizable chemicals should be protected from physical damage and ignition sources.

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• When handling peroxidizable compounds stored in cylinders, care must be taken to ensure that the cylinders are maintained free of air.

• All peroxidizable liquids, whether open or not, should never be used or stored beyond the expiration date printed on the container.

Ethyl Ether

Storage and Quantity:

Required Safe Practices:

• Use the grade of ether designed for the procedure. Do not use anhydrous ether unless the procedure requires it.

• Lab personnel must wear personal protective equipment (including eye protection).

• Ether spills can be absorbed with a wet sponge or paper towel. The wet material must be placed in a fume hood for vapor evaporation.

• When ether is transferred to another container, the new container must be properly labeled. The new container should not be glass.

• For disposal of large quantities of ether, call the Occupational and Environmental Safety Department at extension 6360.

Hazards:

Ether has a relatively low toxicity, especially in the context of laboratory use. However, it is extremely flammable with a flashpoint of -45oC.

CO2, ABC, or BC dry powder fire extinguishers are to be used in areas with ether.

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Good general ventilation is required. The Occupational and Environmental Safety Department should be contacted to determine adequacy of local ventilation in areas in which ether is used.

9. Safe Handling of Carcinogens, Mutagens, and Teratogens

General Information:

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Chemical Review and Approval:

10. Chemical Waste Disposal

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Waste Definitions:

Ignitable

Corrosive

Toxic

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Reactive

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Specific materials which cannot be put into laboratory drains under any circumstances include:

• Solids large enough to plug lines

• Combustible, flammable or explosive wastes

• Wastes which are toxic or inhibitory to biological waste treatment

• Large quantities of water insolubles which may settle and plug lines

• Highly reactive materials (i.e., strong oxidizers such as phosphorous oxychloride)

• Radioactive materials • Carcinogenic agents or suspected carcinogens

• Corrosive wastes that cannot be neutralized

• RCRA listed wastes

Ethidium Bromide Waste

Aqueous Solutions of EtBr

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Acrylamide and Agarose Gels Containing EtBr

All gels containing EtBr are to be surrendered to the Chemical Waste Program.

Alcohol Solutions of EtBr

Combined EtBr and alcohol solutions are flammable. Therefore, regardless of the concentration of EtBr, all of this material must be surrendered to the Chemical Waste Program.

Lab ware contaminated with EtBr

11. Laboratory Procedures

Planning

Waste Minimization

Labeling

Complete and accurate labeling of chemical waste containers is absolutely essential. A properly labeled bottle serves several vital purposes. The primary purpose is safety. Personnel who handle dozens of waste containers collected each week must be able to protect themselves by taking precautions which are commensurate with the hazards of the materials being handled. Labeling of waste containers is also important while the material is still in the laboratory. It aids in the proper segregation of different waste types and helps to prevent lab personnel from inadvertently mixing

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incompatibles together in the same waste container. The third major purpose for a properly labeled container dictates the correct disposal route to be followed after collection. A label which reads "waste solvents" or "organic waste" is not useful. Wastes labeled as such or not labeled at all are refused until sufficient analysis is performed to properly characterize the material.

Materials collected for disposal must be prepared as follows:

• Miscellaneous laboratory reagents must be in strong, tight containers and must have a positive- type closure in good condition (no corks or plugs).

• Waste acids cannot be mixed and must also be in glass jugs of not more than one gallon capacity. They too must have a screw-type closure (no corks or plugs).

Laboratory Relocation/Chemical Moves:

12. Hazard Communication

These SDSs can also be obtained through MSDSonline®. Any questions about the use of this service or about Safety Data Sheets can be directed to the Occupational and Environmental Safety Department.

assistance.

13. The OSHA Laboratory Standard

REQUIREMENTS:

Employee Exposure Determination

An employee’s exposure to a hazardous chemical must be measured if there is reason to believe that exposure levels routinely exceed an action level or permissible exposure limit (PEL).

Chemical Hygiene Plan

Employee Training and Information

Employees must be informed of:

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Employees must be trained on:

Medical Consultation and Examination

Hazard Identification

Respirator Use

Where respirators are necessary to maintain exposure levels below the PEL, the employer must provide them at no cost to the employee.

14. Safety Data Sheets (SDS)

Federal regulations require chemical manufacturers to provide specific safety information on their chemical products to anyone who purchases them. This information is communicated through a

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Appendix A: EPA List of Hazardous Wastes

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P045 39196–18–4 2-Butanone, 3,3-dimethyl-1-(methylthio)-O- [methylamino)carbonyl]oxime P021 592–01–8 Calcium cyanide P021 592–01–8 Calcium cyanide Ca(CN)2 P189 55285–14–8 Carbamic acid, [(dibutylamino)- thio]methyl-, 2,3-dihydro-2,2- dimethyl- 7-benzofuranyl ester. P191 644–64–4 Carbamic acid, dimethyl-, 1-[(dimethylamino)carbonyl]- 5- methyl-1H- pyrazol-3-yl ester. P192 119–38–0 Carbamic acid, dimethyl-, 3-methyl-1- (1- methylethyl)-1H- pyrazol-5-yl ester. P190 1129–41–5 Carbamic acid, methyl-, 3-methylphenyl ester. P127 1563–66–2 Carbofuran. P022 75–15–0 Carbon disulfide P095 75–44–5 Carbonic dichloride P189 55285–14–8 Carbosulfan. P023 107–20–0 Chloroacetaldehyde P024 106–47–8 p-Chloroaniline P026 5344–82–1 1-(o-Chlorophenyl)thiourea P027 542–76–7 3-Chloropropionitrile P029 544–92–3 Copper cyanide P029 544–92–3 Copper cyanide Cu(CN) P202 64–00–6 m-Cumenyl methylcarbamate. P030 Cyanides (soluble cyanide salts), not otherwise specified P031 460–19–5 Cyanogen P033 506–77–4 Cyanogen chloride P033 506–77–4 Cyanogen chloride (CN)Cl P034 131–89–5 2-Cyclohexyl-4,6-dinitrophenol P016 542–88–1 Dichloromethyl ether P036 696–28–6 Dichlorophenylarsine P037 60–57–1 Dieldrin P038 692–42–2 Diethylarsine P041 311–45–5 Diethyl-p-nitrophenyl phosphate P040 297–97–2 O,O-Diethyl O-pyrazinyl phosphorothioate P043 55–91–4 Diisopropylfluorophosphate (DFP) P004 309–00–2 1,4,5,8-Dimethanonaphthalene, 1,2,3,4,10,10-hexachloro- 1,4,4a,5,8,8a,- P060 465–73–6 1,4,5,8-Dimethanonaphthalene, 1,2,3,4,10,10-hexachloro- 1,4,4a,5,8,8a- hexahydro- P037 60–57–1 2,7:3,6-Dimethanonaphth[2,3-b]oxirene, 3,4,5,6,9,9 -hexachloro- 1a,2,2a,3,6,6a,7,7a- octahydro-

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P051 72–20–8 2,7:3,6-Dimethanonaphth [2,3-b]oxirene, 3,4,5,6,9,9-hexachloro- 1a,2,2a,3,6,6a,7,7a- octahydro- P044 60–51–5 Dimethoate P046 122–09–8 alpha,alpha-Dimethylphenethylamine P191 644–64–4 Dimetilan. P047 534–52–1 4,6-Dinitro-o-cresol, & salts P048 51–28–5 2,4-Dinitrophenol P020 88–85–7 Dinoseb P085 152–16–9 Diphosphoramide, octamethyl- P111 107–49–3 Diphosphoric acid, tetraethyl ester P039 298–04–4 Disulfoton P049 541–53–7 Dithiobiuret P185 26419–73–8 1,3-Dithiolane-2-carboxaldehyde, 2,4- dimethyl-, O- [(methylamino)- carbonyl]oxime P050 115–29–7 Endosulfan P088 145–73–3 Endothall P051 72–20–8 Endrin P051 72–20–8 Endrin, & metabolites P042 51–43–4 Epinephrine P031 460–19–5 Ethanedinitrile P194 23135–22–0 Ethanimidothioc acid, 2-(dimethylamino)-N- [[(methylamino) carbonyl]oxy]-2-oxo-, methyl ester. P066 16752–77–5 Ethanimidothioic acid,N- [[(methylamino)carbonyl]oxy]-, methyl ester P101 107–12–0 Ethyl cyanide P054 151–56–4 Ethyleneimine P097 52–85–7 Famphur P056 7782–41–4 Fluorine P057 640–19–7 Fluoroacetamide P058 62–74–8 Fluoroacetic acid, sodium salt P198 23422–53–9 Formetanate hydrochloride. P197 17702–57–7 Formparanate. P065 628–86–4 Fulminic acid, mercury(2+) salt (R,T) P059 76–44–8 Heptachlor P062 757–58–4 Hexaethyl tetraphosphate P116 79–19–6 Hydrazinecarbothioamide P068 60–34–4 Hydrazine, methyl- P063 74–90–8 Hydrocyanic acid

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P063 74–90–8 Hydrogen cyanide P096 7803–51–2 Hydrogen phosphide P060 465–73–6 Isodrin P192 119–38–0 Isolan. P202 64–00–6 3-Isopropylphenyl N-methylcarbamate. P007 2763–96–4 3(2H)-Isoxazolone, 5-(aminomethyl)- P196 15339–36–3 Manganese, bis(dimethylcarbamodithioato- S,S -, ) P196 15339–36–3 Manganese dimethyldithiocarbamate. P092 62–38–4 Mercury, (acetato-O)phenyl- P065 628–86–4 Mercury fulminate (R,T) P082 62–75–9 Methanamine, N-methyl-N-nitroso- P064 624–83–9 Methane, isocyanato- P016 542–88–1 Methane, oxybis[chloro- P112 509–14–8 Methane, tetranitro- (R) P118 75–70–7 Methanethiol, trichloro- P198 23422–53–9 Methanimidamide, N,N-dimethyl-N -[3- [[(methylamino)- carbonyl]oxy]phenyl]-, monohydrochloride. P197 17702–57–7 Methanimidamide, N,N-dimethyl-N -[2- methyl-4- [[(methylamino)carbonyl]oxy]phenyl]- P050 115–29–7 6,9- P050 115–29–7 6,9-Methano-2,4,3- benzodioxathiepin, 6,7,8,9,10,10-hexachloro- 1,5,5a,6,9,9a- P059 76–44–8 4,7-Methano-1H-indene, 1,4,5,6,7,8,8 - heptachloro-3a,4,7,7a- tetrahydro P199 2032–65–7 Methiocarb. P066 16752–77–5 Methomyl P068 60–34–4 Methyl hydrazine P064 624–83–9 Methyl isocyanate P069 75–86–5 2-Methyllactonitrile P071 298–00–0 Methyl parathion P190 1129–41–5 Metolcarb P128 315–8–4 Mexacarbate P072 86–88–4 alpha-Naphthylthiourea P073 13463–39–3 Nickel carbonyl P073 13463–39–3 Nickel carbonyl Ni(CO)4, (T-4)- P074 557–19–7 Nickel cyanide P074 557–19–7 Nickel cynaide Ni(CN)2 P075 54–11–5 Nicotine, & salts

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P076 10102–43–9 Nitric oxide P077 100–01–6 p-Nitroaniline P078 10102–44–0 Nitrogen dioxide P076 10102–43–9 Nitrogen oxide NO P078 10102–44–0 Nitrogen oxide NO2 P081 55–63–0 Nitroglycerine (R) P082 62–75–9 N-Nitrosodimethylamine P084 4549–40–0 N-Nitrosomethylvinylamine P085 152–16–9 Octamethylpyrophosphoramide P087 20816–12–0 Osmium oxide OsO4, (T-4)- P087 20816–12–0 Osmium tetroxide P088 145–73–3 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid P194 23135–22–0 Oxamyl. P089 56–38–2 Parathion P034 131–89–5 Phenol, 2-cyclohexyl-4,6-dinitro- P048 51–28–5 Phenol, 2,4-dinitro- P047 534–52–1 Phenol, 2-methyl-4,6-dinitro-, & salts P020 88–85–7 Phenol, 2-(1-methylpropyl)-4,6-dinitro- P009 131–74–8 Phenol, 2,4,6-trinitro-, ammonium salt (R) P128 315–18–4 Phenol, 4-(dimethylamino)-3,5-dimethyl-, methylcarbamate (ester) P199 2032–65–7 Phenol, (3,5-dimethyl-4-(methylthio)-, methylcarbamate P202 64–00–6 Phenol, 3-(1-methylethyl)-, methyl carbamate P201 2631–37–0 Phenol, 3-methyl-5-(1-methylethyl)-, methyl carbamate P092 62–38–4 Phenylmercury acetate P093 103–85–5 Phenylthiourea P094 298–02–2 Phorate P095 75–44–5 Phosgene P096 7803–51–2 Phosphine P041 311–45–5 Phosphoric acid, diethyl 4-nitrophenyl ester P039 298–04–4 Phosphorodithioic acid, O,O-diethyl S-[2- (ethylthio)ethyl]ester P094 298–02–2 Phosphorodithioic acid, O,O-diethyl S-[ethylthio)methyl]ester P044 60–51–5 Phosphorodithioic acid, O,O-dimethyl S-[2- (methylamino)-2- oxoethyl] ester P043 55–91–4 Phosphorofluoridic acid, bis(1-methylethyl) ester P089 56–38–2 Phosphorothioic acid, O,O-diethyl O-(4- nitrophenyl) ester

13b-34 Updated March 2017

P040 297–97–2 Phosphorothioic acid, O,O-diethyl O-pyrazinyl ester P097 52–85–7 Phosphorothioic acid,O-[4- [(dimethylamino)sulfonyl]phenyl] O,O- dimethyl ester P071 298–00–0 Phosphorothioic acid, O,O,-dimethyl O-(4- nitrophenyl) ester P204 57–47–6 Physostigmine. P188 57–64–7 Physostigmine salicylate P110 78–00–2 Plumbane, tetraethyl- P098 151–50–8 Potassium cyanide P098 151–50–8 Potassium cyanide K(CN) P099 506–61–6 Potassium silver cyanide P201 2631–37–0 Promecarb P070 116–06–3 Propanal, 2-methyl-2-(methylthio)-,O- [(methylamino)carbonyl]oxime P203 1646–88–4 Propanal, 2-methyl-2-(methyl-sulfonyl)-, O- [(methylamino)carbonyl] oxime P101 107–12–0 Propanenitrile P027 542–76–7 Propanenitrile, 3-chloro- P069 75–86–5 Propanenitrile, 2-hydroxy-2-methyl- P081 55–63–0 1,2,3-Propanetriol, trinitrate (R) P017 598–31–2 2-Propanone, 1-bromo- P102 107–19–7 Propargyl alcohol P003 107–02–8 2-Propenal P005 107–18–6 2-Propen-1-ol P067 75–55–8 1,2-Propylenimine P102 107–19–7 2-Propyn-1-ol P008 504–24–5 4-Pyridinamine P075 54–11–5 Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S)-, & salts P204 57–47–6 Pyrrolo[2,3-b]indol-5-ol, 1,2,3,3a,8,8a- hexahydro-1,3a,8- trimethyl-,methylcarbamate (ester), (3aS-cis)- P114 12039–52–0 Selenious acid, dithallium(1+) salt P103 630–10–4 Selenourea P104 506–64–9 Silver cyanide P104 506–64–9 Silver cyanide Ag(CN) P105 26628–22–8 Sodium azide P106 143–33–9 Sodium cyanide P106 143–33–9 Sodium cyanide Na(CN) P108 57–24–9 Strychnidin-10-one, & salts

13b-35 Updated March 2017

P018 357–57–3 Strychnidin-10-one, 2,3-dimethoxy- P108 57–24–9 Strychnine, & salts P115 7446–18–6 Sulfuric acid, dithallium(1+) salt P109 3689–24–5 Tetraethyldithiopyrophosphate P110 78–00–2 Tetraethyl lead P111 107–49–3 Tetraethyl pyrophosphate P112 509–14–8 Tetranitromethane (R) P062 757–58–4 Tetraphosphoric acid, hexaethyl ester P113 1314–32–5 Thallic oxide P113 1314–32–5 Thallium oxide Tl2O3 P114 12039–52–0 Thallium(I) selenite P115 7446–18–6 Thallium(I) sulfate P109 3689–24–5 Thiodiphosphoric acid, tetraethyl ester P045 39196–18–4 Thiofanox P049 541–53–7 Thioimidodicarbonic diamide [(H2N)C(S)]2NH P014 108–98–5 Thiophenol P116 79–19–6 Thiosemicarbazide P026 5344–82–1 Thiourea, (2-chlorophenyl)- P072 86–88–4 Thiourea, 1-naphthalenyl- P093 103–85–5 Thiourea, phenyl- P185 26419–73–8 Tirpate P123 8001–35–2 Toxaphene P118 75–70–7 Trichloromethanethiol P119 7803–55–6 Vanadic acid, ammonium salt P120 1314–62–1 Vanadium oxide V2O5 P120 1314–62–1 Vanadium pentoxide P084 4549–40–0 Vinylamine, N-methyl-N-nitroso- P001 81–81–2 Warfarin, & salts, when present at concentrations greater than 0.3% P205 137–30–4 Zinc, bis(dimethylcarbamodithioato-S,S -, ) P121 557–21–1 Zinc cyanide P121 557–21–1 Zinc cyanide Zn(CN)2 P122 1314–84–7 Zinc phosphide Zn3P2, when present at concentrations greater than 10% (R,T) P205 137–30–4 Ziram. U394 30558–43–1 A2213 U001 75–07–0 Acetaldehyde (I)

13b-36 Updated March 2017

U034 75–87–6 Acetaldehyde, trichloro- U187 62–44–2 Acetamide, N-(4-ethoxyphenyl)- U005 53–96–3 Acetamide, N-9H-fluoren-2-yl- U240 94–75–7 Acetic acid, (2,4-dichlorophenoxy)-, salts & esters U112 141–78–6 Acetic acid ethyl ester (I) U144 301–04–2 Acetic acid, lead(2+) salt U214 563–68–8 Acetic acid, thallium(1+) salt see 93-76-5 Acetic Acid, (2,4,5-trichlorophenoxy)- F027 U002 67–64–1 Acetone (I) U003 75–05–8 Acetonitrile (I,T) U004 98–86–2 Acetophenone U005 53–96–3 2-Acetylaminofluorene U006 75–36–5 Acetyl chloride (C,R,T) U007 79–06–1 Acrylamide U008 79–10–7 Acrylic acid (I) U009 107–13–1 Acrylonitrile U011 61–82–5 Amitrole U012 62–53–3 Aniline (I,T) U136 75–60–5 Arsinic acid, dimethyl- U014 492–80–8 Auramine U015 115–02–6 Azaserine U365 2212–67–1 H-Azepine-1-carbothioic acid, hexahydro-, S- ethyl ester. U010 50–07–7 Azirino[2 -a]indole,3:3,4]pyrrolo[1,2-4,7- dione, 6-amino-8- [[(aminocarbonyl)oxy]methyl]- U280 101–27–9 Barban U278 22781–23–3 Bendiocarb U364 22961–82–6 Bendiocarb phenol U271 17804–35–2 Benomyl U157 56–49–5 Benz[j]aceanthrylene, 1,2-dihydro-3-methyl- U016 225–51–4 Benz[c]acridine U017 98–87–3 Benzal chloride U192 23950–58–5 Benzamide, 3,5-dichloro-N-(1,1-dimethyl-2- propynyl)- U018 56–55–3 Benz[a]anthracene U094 57–97–6 Benz[a]anthracene, 7,12-dimethyl- U012 62–53–3 Benzenamine (I,T) U014 492–80–8 Benzenamine, 4,4 -carbonimidoylbis[N,N- dimethyl- 13b-37 Updated March 2017

U049 3165–93–3 Benzenamine, 4-chloro-2-methyl-, hydrochloride U093 60–11–7 Benzenamine, N,N-dimethyl-4-(phenylazo)- U328 95–53–4 Benzenamine, 2-methyl- U353 106–49–0 Benzenamine, 4-methyl- U158 101–14–4 Benzenamine, 4,4 -methylenebis[2-chloro- U222 636–21–5 Benzenamine, 2-methyl-, hydrochloride U181 99–55–8 Benzenamine, 2-methyl-5-nitro- U019 71–43–2 Benzene (I,T) U038 510–15–6 Benzeneacetic acid, 4-chloro-alpha-(4- chlorophenyl)-alpha- hydroxy-, ethyl ester U030 101–55–3 Benzene, 1-bromo-4-phenoxy- U035 305–03–3 Benzenebutanoic acid, 4-[bis(2- chloroethyl)amino]- U037 108–90–7 Benzene, chloro- U221 25376–45–8 Benzenediamine, ar-methyl- U028 117–81–7 1,2-Benzenedicarboxylic acid, bis(2- ethylhexyl) ester U069 84–74–2 1,2-Benzenedicarboxylic acid, dibutyl ester U088 84–66–2 1,2-Benzenedicarboxylic acid, diethyl ester U102 131–11–3 1,2-Benzenedicarboxylic acid, dimethyl ester U107 117–84–0 1,2-Benzenedicarboxylic acid, dioctyl ester U070 95–50–1 Benzene, 1,2-dichloro- U071 541–73–1 Benzene, 1,3-dichloro- U072 106–46–7 Benzene, 1,4-dichloro- U060 72–54–8 Benzene, 1,1 -(2,2-dichloroethylidene)bis[4- chloro- U017 98–87–3 Benzene, (dichloromethyl)- U223 26471–62–5 Benzene, 1,3-diisocyanatomethyl- (R,T) U239 1330–20–7 Benzene, dimethyl- (I,T) U201 108–46–3 1,3-Benzenediol U127 118–74–1 Benzene, hexachloro- U056 110–82–7 Benzene, hexahydro- (I) U220 108–88–3 Benzene, methyl- U105 121–14–2 Benzene, 1-methyl-2,4-dinitro- U106 606–20–2 Benzene, 2-methyl-1,3-dinitro- U055 98–82–8 Benzene, (1-methylethyl)- (I) U169 98–95–3 Benzene, nitro- U183 608–93–5 Benzene, pentachloro- U185 82–68–8 Benzene, pentachloronitro-

13b-38 Updated March 2017

U020 98–09–9 Benzenesulfonic acid chloride (C,R) U020 98–09–9 Benzenesulfonyl chloride (C,R) U207 95–94–3 Benzene, 1,2,4,5-tetrachloro- U061 50–29–3 Benzene, 1,1 -(2,2,2-trichloroethylidene)bis[4- chloro- U247 72–43–5 Benzene, 1,1 -(2,2,2-trichloroethylidene)bis[4- methoxy- U023 98–07–7 Benzene, (trichloromethyl)- U234 99–35–4 Benzene, 1,3,5-trinitro- U021 92–87–5 Benzidine U202 81–07–2 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide, & salts U278 22781–23–3 1,3-Benzodioxol-4-ol, 2,2-dimethyl-, methyl carbamate U364 22961–82–6 1,3-Benzodioxol-4-ol, 2,2-dimethyl-, U203 94–59–7 1,3-Benzodioxole, 5-(2-propenyl)- U141 120–58–1 1,3-Benzodioxole, 5-(1-propenyl)- U367 1563–38–8 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl- U090 94–58–6 1,3-Benzodioxole, 5-propyl- U064 189–55–9 Benzo[rst]pentaphene U248 181–81–2 2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo- 1-phenyl-butyl)-, & salts, when present at concentrations of 0.3% or U022 50–32–8 Benzo[a]pyrene U197 106–51–4 p-Benzoquinone U023 98–07–7 Benzotrichloride (C,R,T) U085 1464–53–5 2,2 -Bioxirane U021 92–87–5 [1,1-Biphenyl]-4,4 -diamine U073 91–94–1 [1,1 -Biphenyl]-4,4 -diamine, 3,3 -dichloro- U091 119–90–4 [1,1 -Biphenyl]-4,4 -diamine, 3,3 -dimethoxy- U095 119–93–7 [1,1 -Biphenyl]-4,4 -diamine, 3,3 -dimethyl- U401 97–74–5 Bis(dimethylthiocarbamoyl) sulfide. U400 120–54–7 Bis(pentamethylene)thiuram tetrasulfide. U225 75–25–2 Bromoform U030 101–55–3 4-Bromophenyl phenyl ether U128 87–68–3 1,3-Butadiene, 1,1,2,3,4,4-hexachloro- U172 924–16–3 1-Butanamine, N-butyl-N-nitroso- U031 71–36–3 1-Butanol (I) U159 78–93–3 2-Butanone (I,T) U160 1338–23–4 2-Butanone, peroxide (R,T) U053 4170–30–3 2-Butenal U074 764–41–0 2-Butene, 1,4-dichloro- (I,T)

13b-39 Updated March 2017

U143 303–34–4 2-Butenoic acid, 2-methyl-, 7-[[2,3-dihydroxy- 2-(1- methoxyethyl)-3-methyl-1- oxobutoxy]methyl]- U031 71–36–3 n-Butyl alcohol (I) U392 2008–41–5 Butylate. U136 75–60–5 Cacodylic acid U032 13765–19–0 Calcium chromate U372 10605–21–7 Carbamic acid, 1H-benzimidazol-2-yl, methyl ester U271 17804–35–2 Carbamic acid, [1-[(butylamino)carbonyl]-1H- benzimidazol-2- yl]-, methyl ester. U375 55406–53–6 Carbamic acid, butyl-, 3-iodo-2-propynyl ester U280 101–27–9 Carbamic acid, (3-chlorophenyl)-, 4-chloro-2- butynyl ester U238 51–79–6 Carbamic acid, ethyl ester U178 615–53–2 Carbamic acid, methylnitroso-, ethyl ester U373 122–42–9 Carbamic acid, phenyl-, 1-methylethyl ester U409 23564–05–8 Carbamic acid, [1,2-phenylenebis (iminocarbonothioyl)]bis-, dimethyl ester U097 79–44–7 Carbamic chloride, dimethyl- U379 136–30–1 Carbamodithioic acid, dibutyl, sodium salt. U277 95–06–7 Carbamodithioic acid, diethyl-, 2-chloro-2- propenyl ester U381 148–18–5 Carbamodithioic acid, diethyl-, sodium salt. U383 128–03–0 Carbamodithioic acid, dimethyl, potassium salt U382 128–04–1 Carbamodithioic acid, dimethyl-, sodium salt. U376 144–34–3 Carbamodithioic acid, dimethyl-, tetraanhydrosulfide with orthothioselenious acid U378 51026–28–9 Carbamodithioic acid, (hydroxymethyl)methyl- , monopotassium salt U384 137–42–8 Carbamodithioic acid, methyl-, monosodium salt U377 137–41–7 Carbamodithioic acid, methyl,- monopotassium salt U389 2303–17–5 Carbamothioic acid, bis(1-methylethyl)-, S- (2,3,3-trichloro-2- propenyl) ester U392 2008–41–5 Carbamothioic acid, bis(2-methylpropyl)-, S- ethyl ester U391 1114–71–2 Carbamothioic acid, butylethyl-, S-propyl ester U386 1134–23–2 Carbamothioic acid, cyclohexylethyl-, S-ethyl ester U390 759–94–4 Carbamothioic acid, dipropyl-, S-ethyl ester U387 52888–80–9 Carbamothioic acid, dipropyl-, S- (phenylmethyl) ester U385 1929–77–7 Carbamothioic acid, dipropyl-, S-propyl ester U114 111–54–6 Carbamodithioic acid, 1,2-ethanediylbis-, salts & esters U062 2303–16–4 Carbamothioic acid, bis(1-methylethyl)-, S- (2,3-dichloro-2- propenyl) ester

13b-40 Updated March 2017

U279 63–25–2 Carbaryl U372 10605–21–7 Carbendazim U367 1563–38–8 Carbofuran phenol U215 6533–73–9 Carbonic acid, dithallium(1+) salt U033 353–50–4 Carbonic difluoride U156 79–22–1 Carbonochloridic acid, methyl ester (I,T)

U033 353–50–4 Carbon oxyfluoride (R,T) U211 56–23–5 Carbon tetrachloride U034 75–87–6 Chloral U035 305–03–3 Chlorambucil U036 57–74–9 Chlordane, alpha & gamma isomers U026 494–03–1 Chlornaphazin U037 108–90–7 Chlorobenzene U038 510–15–6 Chlorobenzilate U039 59–50–7 p-Chloro-m-cresol U042 110–75–8 2-Chloroethyl vinyl ether U044 67–66–3 Chloroform U046 107–30–2 Chloromethyl methyl ether U047 91–58–7 beta-Chloronaphthalene U048 95–57–8 o-Chlorophenol U049 3165–93–3 4-Chloro-o-toluidine, hydrochloride U032 13765–19–0 Chromic acid H2CrO4, calcium salt U050 218–01–9 Chrysene U393 137–29–1 Copper, bis(dimethylcarbamodithioato-S,S’)-, U393 137–29–1 Copper dimethyldithiocarbamate. U051 Creosote U052 1319–77–3 Cresol (Cresylic acid) U053 4170–30–3 Crotonaldehyde U055 98–82–8 Cumene (I) U246 506–68–3 Cyanogen bromide (CN)Br U386 1134–23–2 Cycloate. U197 106–51–4 2,5-Cyclohexadiene-1,4-dione U056 110–82–7 Cyclohexane (I) U129 58–89–9 Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3beta,4alpha,5alpha,6beta)- U057 108–94–1 Cyclohexanone (I)

13b-41 Updated March 2017

U130 77–47–4 1,3-Cyclopentadiene, 1,2,3,4,5,5-hexachloro- U058 50–18–0 Cyclophosphamide U240 94–75–7 2,4-D, salts & esters U059 20830–81–3 Daunomycin U366 533–74–4 Dazomet. U060 72–54–8 DDD U061 50–29–3 DDT U062 2303–16–4 Diallate U063 53–70–3 Dibenz[a,h]anthracene U064 189–55–9 Dibenzo[a,i]pyrene U066 96–12–8 1,2-Dibromo-3-chloropropane U069 84–74–2 Dibutyl phthalate U070 95–50–1 o-Dichlorobenzene U071 541–73–1 m-Dichlorobenzene U072 106–46–7 p-Dichlorobenzene U073 91–94–1 3,3 -Dichlorobenzidine U074) 764–41–0 1,4-Dichloro-2-butene (I,T) U075 75–71–8 Dichlorodifluoromethane U078 75–35–4 1,1-Dichloroethylene U079 156–60–5 1,2-Dichloroethylene U025 111–44–4 Dichloroethyl ether U027 108–60–1 Dichloroisopropyl ether U024 111–91–1 Dichloromethoxy ethane U081 120–83–2 2,4-Dichlorophenol U082 87–65–0 2,6-Dichlorophenol U084 542–75–6 1,3-Dichloropropene U085 1464–53–5 1,2:3,4-Diepoxybutane (I,T) U108 123–91–1 1,4-Diethyleneoxide U028 117–81–7 Diethylhexyl phthalate U395 5952–26–1 Diethylene glycol, dicarbamate U086 1615–80–1 N,N -Diethylhydrazine U087 3288–58–2 O,O-Diethyl S-methyl dithiophosphate U088 84–66–2 Diethyl phthalate U089 56–53–1 Diethylstilbesterol U090 94–58–6 Dihydrosafrole

13b-42 Updated March 2017

U091 119–90–4 3,3 -Dimethoxybenzidine U092 124–40–3 Dimethylamine (I) U093 60–11–7 p-Dimethylaminoazobenzene U094 57–97–6 7,12-Dimethylbenz[a]anthracene U095 119–93–7 3,3 -Dimethylbenzidine U096 80–15–9 alpha,alpha-Dimethylbenzylhydroperoxide (R) U097 79–44–7 Dimethylcarbamoyl chloride U098 57–14–7 1,1-Dimethylhydrazine U099 540–73–8 1,2-Dimethylhydrazine U101 105–67–9 2,4-Dimethylphenol U102 131–11–3 Dimethyl phthalate U103 77–78–1 Dimethyl sulfate U105 121–14–2 2,4-Dinitrotoluene U106 606–20–2 2,6-Dinitrotoluene U107 117–84–0 Di-n-octyl phthalate U108 123–91–1 1,4-Dioxane U109 122–66–7 1,2-Diphenylhydrazine U110 142–84–7 Dipropylamine (I) U111 621–64–7 Di-n-propylnitrosamine U403. 97–77–8 Disulfiram. U390 759–94–4 EPTC. U041 106–89–8 Epichlorohydrin U001 75–07–0 Ethanal (I) U404 121–44–8 Ethanamine, N,N-diethyl- U174 55–18–5 Ethanamine, N-ethyl-N-nitroso- U155 91–80–5 1,2-Ethanediamine, N,N-dimethyl-N -2- pyridinyl-N -(2- thienylmethyl)- U067 106–93–4 Ethane, 1,2-dibromo- U076 75–34–3 Ethane, 1,1-dichloro- U077 107–06–2 Ethane, 1,2-dichloro- U131 67–72–1 Ethane, hexachloro- U024 111–91–1 Ethane, 1,1 -[methylenebis(oxy)]bis[2-chloro- U117 60–29–7 Ethane, 1,1 -oxybis-(I) U025 111–44–4 Ethane, 1,1 -oxybis[2-chloro- U184 76–01–7 Ethane, pentachloro- U208 630–20–6 Ethane, 1,1,1,2-tetrachloro-

13b-43 Updated March 2017

U209 79–34–5 Ethane, 1,1,2,2-tetrachloro- U218 62–55–5 Ethanethioamide U226 71–55–6 Ethane, 1,1,1-trichloro- U227 79–00–5 Ethane, 1,1,2-trichloro- U410 59669–26–0 Ethanimidothioic acid, N,N’- [thiobis[(methylimino)carbonyloxy]]bis-, dimethyl U394 30558–43–1 Ethanimidothioic acid, 2-(dimethylamino)-N- hydroxy-2-oxo-, methyl ester. U359 110–80–5 Ethanol, 2-ethoxy- U173 1116–54–7 Ethanol, 2,2 -(nitrosoimino)bis- U395 5952–26–1 Ethanol, 2,2 -oxybis-, dicarbamate. U004 98–86–2 Ethanone, 1-phenyl- U043 75–01–4 Ethene, chloro- U042 110–75–8 Ethene, (2-chloroethoxy)- U078 75–35–4 Ethene, 1,1-dichloro- U079 156–60–5 Ethene, 1,2-dichloro-, (E)- U210 127–18–4 Ethene, tetrachloro- U228 79–01–6 Ethene, trichloro- U112 141–78–6 Ethyl acetate (I) U113 140–88–5 Ethyl acrylate (I) U238 51–79–6 Ethyl carbamate (urethane) U117 60–29–7 Ethyl ether (I) U114 111–54–6 Ethylenebisdithiocarbamic acid, salts & esters U067 106–93–4 Ethylene dibromide U077 107–06–2 Ethylene dichloride U359 110–80–5 Ethylene glycol monoethyl ether U115 75–21–8 Ethylene oxide (I,T) U116 96–45–7 Ethylenethiourea U076 75–34–3 Ethylidene dichloride U118 97–63–2 Ethyl methacrylate U119 62–50–0 Ethyl methanesulfonate U407 14324–55–1 Ethyl Ziram U396 14484–64–1 Ferbam U120 206–44–0 Fluoranthene U122 50–00–0 Formaldehyde U123 64–18–6 Formic acid (C,T) U124 110–00–9 Furan (I)

13b-44 Updated March 2017

U125 98–01–1 2-Furancarboxaldehyde (I) U147 108–31–6 2,5-Furandione U213 109–99–9 Furan, tetrahydro-(I) U125 98–01–1 Furfural (I) U124 110–00–9 Furfuran (I) U206 18883–66–4 Glucopyranose, 2-deoxy-2-(3-methyl-3- nitrosoureido)-, DU20 18883–66–4 D-Glucose, 2-deoxy-2-[[(methylnitrosoamino)- carbonyl]amino]- 6 U126 765–34–4 Glycidylaldehyde U163 70–25–7 Guanidine, N-methyl-N -nitro-N-nitroso- U127 118–74–1 Hexachlorobenzene U128 87–68–3 Hexachlorobutadiene U130 77–47–4 Hexachlorocyclopentadiene U131 67–72–1 Hexachloroethane U132 70–30–4 Hexachlorophene U243 1888–71–7 Hexachloropropene U133 302–01–2 Hydrazine (R,T) U086 1615–80–1 Hydrazine, 1,2-diethyl- U098 57–14–7 Hydrazine, 1,1-dimethyl- U099 540–73–8 Hydrazine, 1,2-dimethyl- U109 122–66–7 Hydrazine, 1,2-diphenyl- U134 7664–39–3 Hydrofluoric acid (C,T) U134 7664–39–3 Hydrogen fluoride (C,T) U135 7783–06–4 Hydrogen sulfide U135 7783–06–4 Hydrogen sulfide H2S U096 80–15–9 Hydroperoxide, 1-methyl-1-phenylethyl- (R) U116 96–45–7 2-Imidazolidinethione U137 193–39–5 Indeno[1,2,3-cd]pyrene U375 55406–53–6 3-Iodo-2-propynyl n-butylcarbamate U396 14484–64–1 Iron, tris(dimethylcarbamodithioato-S,S -, ) U190 85–44–9 1,3-Isobenzofurandione U140 78–83–1 Isobutyl alcohol (I,T) U141 120–58–1 Isosafrole U142 143–50–0 Kepone U143 303–34–4 Lasiocarpine U144 301–04–2 Lead acetate

13b-45 Updated March 2017

U146 1335–32–6 Lead, bis(acetato-O)tetrahydroxytri- U145 7446–27–7 Lead phosphate U146 1335–32–6 Lead subacetate U129 58–89–9 Lindane U163 70–25–7 MNNG U147 108–31–6 Maleic anhydride U148 123–33–1 Maleic hydrazide U149 109–77–3 Malononitrile U150 148–82–3 Melphalan U151 7439–97–6 Mercury U384 137–42–8 Metam Sodium. U152 126–98–7 Methacrylonitrile (I, T) U092 124–40–3 Methanamine, N-methyl- (I) U029 74–83–9 Methane, bromo- U045 74–87–3 Methane, chloro- (I, T) U046 107–30–2 Methane, chloromethoxy- U068 74–95–3 Methane, dibromo- U080 75–09–2 Methane, dichloro- U075 75–71–8 Methane, dichlorodifluoro- U138 74–88–4 Methane, iodo- U119 62–50–0 Methanesulfonic acid, ethyl ester U211 56–23–5 Methane, tetrachloro- U153 74–93–1 Methanethiol (I, T) U225 75–25–2 Methane, tribromo- U044 67–66–3 Methane, trichloro- U121 75–69–4 Methane, trichlorofluoro- U036 57–74–9 4,7-Methano-1H-indene, 1,2,4,5,6,7,8,8- octachloro-2,3,3a,4,7,7a- hexahydro- U154 67–56–1 Methanol (I) U155 91–80–5 Methapyrilene U142 143–50–0 1,3,4-Metheno-2H-cyclobuta[cd]pentalen-2- one, 1,1a,3,3a,4,5,5,5a,5b,6- U247 72–43–5 Methoxychlor U154 67–56–1 Methyl alcohol (I) U029 74–83–9 Methyl bromide U186 504–60–9 1-Methylbutadiene (I) U045 74–87–3 Methyl chloride (I,T)

13b-46 Updated March 2017

U156 79–22–1 Methyl chlorocarbonate (I,T) U226 71–55–6 Methyl chloroform U157 56–49–5 3-Methylcholanthrene U158 101–14–4 4,4 -Methylenebis(2-chloroaniline) U068 74–95–3 Methylene bromide U080 75–09–2 Methylene chloride U159 78–93–3 Methyl ethyl ketone (MEK) (I,T) U160 1338–23–4 Methyl ethyl ketone peroxide (R,T) U138 74–88–4 Methyl iodide U161 108–10–1 Methyl isobutyl ketone (I) U162 80–62–6 Methyl methacrylate (I,T) U161 108–10–1 4-Methyl-2-pentanone (I) U164 56–04–2 Methylthiouracil U010 50–07–7 Mitomycin C U365 2212–67–1 Molinate U059 20830–81–3 5,12-Naphthacenedione, 8-acetyl-10-[(3- amino-2,3,6-trideoxy)- alpha-L-lyxo- hexopyranosyl)oxy]-7,8,9,10- U167 134–32–7 1-Naphthalenamine U168 91–59–8 2-Naphthalenamine U026 494–03–1 Naphthalenamine, N,N -bis(2-chloroethyl)- U165 91–20–3 Naphthalene U047 91–58–7 Naphthalene, 2-chloro- U166 130–15–4 1,4-Naphthalenedione U236 72–57–1 2,7-Naphthalenedisulfonic acid, 3,3 -[(3,3 - dimethyl[1,1’- biphenyl]-4,4’-diyl)bis(azo)bis[5- amino-4- U279 63–25–2 1-Naphthalenol, methylcarbamate U166 130–15–4 1,4-Naphthoquinone U167 134–32–7 alpha-Naphthylamine U168 91–59–8 beta-Naphthylamine U217 10102–45–1 Nitric acid, thallium(1+) salt U169 98–95–3 Nitrobenzene (I,T) U170 100–02–7 p-Nitrophenol U171 79–46–9 2-Nitropropane (I,T) U172 924–16–3 N-Nitrosodi-n-butylamine U173 1116–54–7 N-Nitrosodiethanolamine U174 55–18–5 N-Nitrosodiethylamine U176 759–73–9 N-Nitroso-N-ethylurea

13b-47 Updated March 2017

U177 684–93–5 N-Nitroso-N-methylurea U178 615–53–2 N-Nitroso-N-methylurethane U179 100–75–4 N-Nitrosopiperidine U180 930–55–2 N-Nitrosopyrrolidine U181 99–55–8 5-Nitro-o-toluidine U193 1120–71–4 1,2-Oxathiolane, 2,2-dioxide U058 50–18–0 2H-1,3,2-Oxazaphosphorin-2-amine,N,N- bis(2- chloroethyl)tetrahydro-, 2-oxide U115 75–21–8 Oxirane (I,T) U126 765–34–4 Oxiranecarboxyaldehyde U041 106–89–8 Oxirane, (chloromethyl)- 2 123–63–7 Paraldehyde U391 1114–71–2 Pebulate. U183 608–93–5 Pentachlorobenzene U184 76–01–7 Pentachloroethane U185 82–68–8 Pentachloronitrobenzene (PCNB) See 87–86–5 Pentachlorophenol F027 U161 108–10–1 Pentanol, 4-methyl- U186 504–60–9 1,3-Pentadiene (I) U187 62–44–2 Phenacetin U188 108–95–2 Phenol U048 95–57–8 Phenol, 2-chloro- U039 59–50–7 Phenol, 4-chloro-3-methyl- U081 120–83–2 Phenol, 2,4-dichloro- U082 87–65–0 Phenol, 2,6-dichloro- U089 56–53–1 Phenol, 4,4 -(1,2-diethyl-1,2-ethenediyl)bis-, (E)- U101 105–67–9 Phenol, 2,4-dimethyl- U052 1319–77–3 Phenol, methyl- U132 70–30–4 Phenol, 2,2 -methylenebis[3,4,6-trichloro- U411 114–26–1. Phenol, 2-(1-methylethoxy)-, methylcarbamate.

U170 100–02–7 Phenol, 4-nitro- See 87–86–5 Phenol, pentachloro- F027 See 58–90–2 Phenol, 2,3,4,6-tetrachloro- F027 See 95-95-4 Phenol, 2,4,5-trichloro- F027

13b-48 Updated March 2017

See 88–06–2 Phenol, 2,4,6-trichloro- F027 U150 148–82–3 L-Phenylalanine, 4-[bis(2-chloroethyl)amino]- U145 7446–27–7 Phosphoric acid, lead(2+) salt (2:3) U087 3288–58–2 Phosphorodithioic acid, O,O-diethyl S-methyl ester U189 1314–80–3 Phosphorus sulfide (R) U190 85–44–9 Phthalic anhydride U191 109–06–8 2-Picoline U179 100–75–4 Piperidine, 1-nitroso- U400 120–54–7 Piperidine, 1,1 -(tetrathiodicarbonothioyl)-bis- U383 128–03–0 Potassium dimethyldithiocarbamate U378 51026–28–9 Potassium n-hydroxymethyl- n-methyldithiocarbamate U377 137–41–7 Potassium n-methyldithiocarbamate U192 23950–58–5 Pronamide U194 107–10–8 1-Propanamine (I,T) U111 621–64–7 1-Propanamine, N-nitroso-N-propyl- U110 142–84–7 1-Propanamine, N-propyl- (I) U066 96–12–8 Propane, 1,2-dibromo-3-chloro- U083 78–87–5 Propane, 1,2-dichloro- U149 109–77–3 Propanedinitrile U171 79–46–9 Propane, 2-nitro- (I,T) U027 108–60–1 Propane, 2,2 -oxybis[2-chloro- U193 1120–71–4 1,3-Propane sultone See 93–72–1 Propanoic acid, 2-(2,4,5-trichlorophenoxy)- F027 U235 126–72–7 1-Propanol, 2,3-dibromo-, phosphate (3:1) U140 78–83–1 1-Propanol, 2-methyl- (I,T) U002 67–64–1 2-Propanone (I) U007 79–06–1 2-Propenamide U084 542–75–6 1-Propene, 1,3-dichloro- U243 1888–71–7 1-Propene, 1,1,2,3,3,3-hexachloro- U009 107–13–1 2-Propenenitrile U152 126–98–7 2-Propenenitrile, 2-methyl- (I,T) U008 79–10–7 2-Propenoic acid (I) U113 140–88–5 2-Propenoic acid, ethyl ester (I) U118 97–63–2 2-Propenoic acid, 2-methyl-, ethyl ester

13b-49 Updated March 2017

U162 80–62–6 2-Propenoic acid, 2-methyl-, methyl ester (I,T) U373 122–42–9 Propham U411 114–26–1 Propoxur U387 52888–80–9 Prosulfocarb U194 107–10–8 n-Propylamine (I,T) U083 78–87–5 Propylene dichloride U148 123–33–1 3,6-Pyridazinedione, 1,2-dihydro- U196 110–86–1 Pyridine U191 109–06–8 Pyridine, 2-methyl- U237 66–75–1 2,4-(1H,3H)-Pyrimidinedione, 5-[bis(2- chloroethyl)amino]- U164 56–04–2 4(1H)-Pyrimidinone, 2,3-dihydro-6-methyl-2- thioxo- U180 930–55–2 Pyrrolidine, 1-nitroso- U200 50–55–5 Reserpine U201 108–46–3 Resorcinol U202 81–07–2 Saccharin, & salts U203 94–59–7 Safrole U204 7783–00–8 Selenious acid U204 7783–00–8 Selenium dioxide U205 7488–56–4 Selenium sulfide U205 7488–56–4 Selenium sulfide SeS2 (R,T) U376 144–34–3 Selenium, tetrakis(dimethyldithiocarbamate) U015 115–02–6 L-Serine, diazoacetate (ester) See 93–72–1 Silvex (2,4,5-TP) F027 U379 136–30–1 Sodium dibutyldithiocarbamate. U381 148–18–5 Sodium diethyldithiocarbamate U382 128–04–1 Sodium dimethyldithiocarbamate U206 18883–66–4 Streptozotocin U103 77–78–1 Sulfuric acid, dimethyl ester U277 95–06–7 Sulfallate U189 1314–80–3 Sulfur phosphide (R) See 2,4,5-T 2,4,5-T F027 U402 1634–02–2 Tetrabutylthiuram disulfide U207 95–94–3 1,2,4,5-Tetrachlorobenzene U208 630–20–6 1,1,1,2-Tetrachloroethane

13b-50 Updated March 2017

U209 79–34–5 1,1,2,2-Tetrachloroethane U210 127–18–4 Tetrachloroethylene See 58–90–2 2,3,4,6-Tetrachlorophenol F027 U213 109–99–9 Tetrahydrofuran (I) U401 97–74–5 Tetramethylthiuram monosulfide U214 563–68–8 Thallium(I) acetate U215 6533–73–9 Thallium(I) carbonate U216 7791–12–0 Thallium(I) chloride U216 7791–12–0 Thallium chloride Tlcl U217 10102–45–1 Thallium(I) nitrate U366 533–74–4 2H-1,3,5-Thiadiazine- 2-thione, tetrahydro- 3,5-dimethyl- U218 62–55–5 Thioacetamide U410 59669–26–0 Thiodicarb. U153 74–93–1 Thiomethanol (I,T) U244 137–26–8 Thioperoxydicarbonic diamide [(H2N)C(S)]2S2, tetramethyl- U402 1634–02–2 Thioperoxydicarbonic diamide, tetrabutyl U403 97–77–8 Thioperoxydicarbonic diamide, tetraethyl U409 23564–05–8 Thiophanate-methyl U219 62–56–6 Thiourea U244 137–26–8 Thiram U220 108–88–3 Toluene U221 25376–45–8 Toluenediamine U223 26471–62–5 Toluene diisocyanate (R,T) U328 95–53–4 o-Toluidine U353 106–49–0 p-Toluidine U222 636–21–5 o-Toluidine hydrochloride U389 2303–17–5 Triallate U011 61–82–5 1H-1,2,4-Triazol-3-amine U227 79–00–5 1,1,2-Trichloroethane U228 79–01–6 Trichloroethylene U121 75–69–4 Trichloromonofluoromethane See 2,4,5- 2,4,5-Trichlorophenol F027 Trichlorophenol See 88–06–2 2,4,6-Trichlorophenol F027 U404 121–44–8 Triethylamine.

13b-51 Updated March 2017

U234 99–35–4 1,3,5-Trinitrobenzene (R,T) U182 123–63–7 1,3,5-Trioxane, 2,4,6-trimethyl- U235 126–72–7 Tris(2,3-dibromopropyl) phosphate U236 72–57–1 Trypan blue U237 66–75–1 Uracil mustard U176 759–73–9 Urea, N-ethyl-N-nitroso- U177 684–93–5 Urea, N-methyl-N-nitroso- U385 1929–77–7 Vernolate U043 75–01–4 Vinyl chloride U248 81–81–2 Warfarin, & salts, when present at concentrations of 0.3% or less U239 1330–20–7 Xylene (I) U200 50–55–5 Yohimban-16-carboxylic acid, 11,17- dimethoxy-18- [(3,4,5-trimethoxybenzoyl)oxy]-,methyl ester, U407 14324–55–1 Zinc, bis(diethylcarbamodithioato-S,S’)- U249 1314–84–7 Zinc phosphide Zn3P2, when present at concentrations of 10% or less

13b-52 Updated March 2017

Chemical Name Nitrile PVC Neoprene Butyl Comments Acetic Acid, Glacial 4.5 hr 3 hr 7 hr NR Acetone NR NR 10 min > 17 hr Acetonitrile 30 min NR 30 min > 8 hr Ammonium Hydroxide, > 8 hr 4 hr > 6 hr NR

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Key:

PVA = Polyvinyl Alcohol, a special-use glove that provides good protection against many solvents, but dissolves in water! Therefore, it is not recommended for general laboratory use.

NR = Not Recommended

• Latex gloves do not provide adequate protection from most chemicals

• Remember that no glove is good for an indefinite period of time.

• Check gloves after each use for degradation, tears, punctures, or swelling.

• If there is any question regarding the glove's integrity, discard it.

CHEMICAL KEEP OUT OF CONTACT WITH Acetic Acid Chromic acid, nitric acid hydroxyl compounds, ethylene, glycol, perchloric acid, peroxides, permanganates

13b-54 Updated March 2017

Chlorine Ammonia, acetylene, butadiene, butane, methane, propane (or other petroleum gases), hydrogen, sodium carbide, turpentine, benzene, finely divided metals Chlorine Dioxide Ammonia, methane, phosphine, hydrogen sulfide Copper Acetylene, hydrogen peroxide Cumene Hydroperoxide Acids, organic or inorganic Cyanides Acids Flammable liquids Ammonium nitrate, chromic acid, hydrogen peroxide, nitric acid, sodium peroxide, halogens Hydrocarbons Fluorine, chlorine, bromine, chromic acid, sodium peroxide Hydrocyanic Acid Nitric acid, alkali Hydrofluoric Acid Ammonia, aqueous or anhydrous Hydrogen Peroxide Copper, chromium, iron, most metals or thei salts, alcohols, acetone, Hydrogen Sulfide Fuming nitric acid, oxidizing gases, acetylene, ammonia Hypochlorites Acids, activated carbon Iodine Acetylene, ammonia (aqueous or anhydrous), hydrogen Mercury Acetylene, fulminic acid, ammonia Nitrates Sulfuric acid Nitric acid (concentrated) Acetic acid, aniline, chromic acid, hydrocyanic acid, hydrogen Nitrites Acids Nitroparaffins Inorganic bases, amines Oxalic Acid Silver, mercury Oxygen Oils, grease, hydrogen; flammable liquids, solids, or gases Perchloric acid Acetic anhydride, bismuth and its alloys, alcohol, paper, wood Peroxides, organic Acids (organic or mineral), avoid friction, store cold Phosphorus (white) Air, oxygen, alkalies, reducing agents Potassium Carbon tetrachloride, carbon dioxide, water Potassium Chlorate Sulfuric and other acids Potassium Glycerine, ethlylene glycol, benzaldehyde, sulfuric acid Selenides Reducing agents Silver Acetylene, oxalic acid, tartaric acid, ammonium compounds Sodium Carbon tetrachloride, carbon dioxide, water Sodium nitrite Ammonium nitrate and other ammonium salts Sodium Peroxide Ethyl or methyl alcohol, glacial acetic acid, acetic anhydride, Sulfides Acids Sulfuric Acid Potassium chlorate, potassium perchlorate, potassium Tellurides Reducing agents

13b-55 Updated March 2017

Part 13c. Chemical Inventory Guidance

Philadelphia College of Osteopathic Medicine Occupational and Environmental Safety Department

CHEMICAL INVENTORY GUIDANCE A chemical inventory should be readily accessible to all laboratory personnel along with a Safety Data Sheet (SDS) for each chemical. Chemical Owners must maintain their chemical inventories in the PCOM Chemical Inventory Database.

• All laboratories and other work areas are required to maintain a complete inventory of all chemicals including the types, quantities and locations where these chemicals are being stored and used at the College. The inventory is a yearly average of what is in the lab at any one time. If the quantity of a chemical is continuously fluctuating due to use, estimate on the higher end to ensure it is not underestimated.

• Chemical inventories should be conducted on at least a yearly basis. Personnel should be looking at the physical condition of primary and secondary containers. Chemicals should be inspected for signs of decomposition, such as discoloration, turbidity, caking, moisture in dry chemicals, particulates in liquids, and pressure buildup. However, as new chemicals are received, the inventory in the database should be updated to include them.

• Updating of chemical inventories and Safety Data Sheets (SDSs) is an ongoing task. As new chemicals or updated SDSs for existing chemicals are received, the corresponding chemical inventory must be updated. At the same time, the PCOM Safety Data Sheet web-based database must be checked to ensure the SDS is available.

This guidance is provided by the PCOM Occupational and Environmental Safety Department. It applies mainly to laboratory workers at PCOM and does not supplant guidelines established by other PCOM departments.

13c-1

Part 14. Formaldehyde Guidance

Philadelphia College of Osteopathic Medicine Occupational and Environmental Safety Department

Guidelines for Safe Use of Formaldehyde

Formaldehyde

Formaldehyde is an organic chemical usually used in a water solution as a preservative and disinfectant. Formaldehyde is used as preservative in a liquid solution that is 37% formaldehyde by weight generally inhibited with 6-12% methyl alcohol. At this concentration, the solution is called formalin. Formaldehyde is a colorless, flammable chemical that has a strong odor. Formaldehyde is a potential human carcinogen. Exposure routes of formaldehyde can occur through inhalation, skin and eye contact. The target organs for formaldehyde are the eyes and respiratory system.

Exposure Limits

The Occupational Safety and Health Administration’s (OSHA) permissible exposure limit (PEL) is an 8-hour time-weighted average (TWA) of 0.75 parts per million (ppm) and a short-term exposure limit (STEL) of 2 ppm. A TWA is used to calculate a workers’ daily exposure to a hazardous substance (such as chemicals, dust, fumes, mists, gases or vapors) or agent (such as occupational noise), averaged to an 8-hour workday, taking into account the average levels of the substance or agent and the time spent in the area. A STEL is the acceptable average exposure over a short period of time, usually 15 minutes as long as the TWA is not exceeded.

Health Effects and Risks

• According to the National Cancer Institute, researchers have concluded that based on data from studies in people and from lab research, exposure to formaldehyde may cause leukemia in humans. Chronic exposure to formaldehyde and its solutions have been associated with cancers of the lung and nasal passageways as well. • Formaldehyde can irritate the eyes, nose, throat and respiratory system. • Exposure to formaldehyde can cause lacrimation and wheezing. • Working with formaldehyde may increase chances of having fertility problems, birth defects or a miscarriage. Most work exposures to formaldehyde are unlikely to be high enough to enter breast milk. However, formaldehyde may enter breast milk at exposure levels that are found in some workplaces, such as anatomy and mortuary science laboratories. • Formaldehyde has been shown to be teratogenic in laboratory animals but human studies have been inconclusive. A teratogen is an agent or factor than can disturb the development of an embryo or fetus.

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The Federal Pregnancy Discrimination Act

What Can Be Done to Reduce or Eliminate Exposure While Pregnant

• If you are pregnant, become pregnant, or are breastfeeding and are working with formaldehyde or formaldehyde solutions, you should consult with your physician for their recommendation. • Protect yourself by talking to your supervisor, faculty member or safety officer to find out the formaldehyde exposure levels in your workplace, and make sure that exposure limits are being followed. o There is evidence that formaldehyde levels higher than 2 ppm can enter the milk of animals, but we do not know how likely this is for humans. • These exposure limits were written for healthy non-pregnant workers, and might not protect an unborn baby. Consider talking to your supervisor, faculty member or safety officer about avoiding duties with formaldehyde exposure on a temporary basis during pregnancy. • If you cannot avoid formaldehyde exposure during pregnancy/breastfeeding: o Wear appropriate gloves when handling formaldehyde. Formaldehyde and other solvents can be absorbed through the skin. Formaldehyde can break through some of the most common types of gloves in 15 minutes or less. Gloves made from butyl rubber, neoprene rubber, or nitrile rubber are generally recommended. Latex rubber, natural rubber, polyethylene, or polyvinyl alcohol gloves are not recommended because they do not offer adequate protection against formaldehyde. Some chemicals can pass through, or permeate, gloves or other PPE very quickly. The companies that sell gloves and other PPE have chemical resistance guides that show how long a specific glove type or fabric will hold up to specific chemicals. Work with your company’s safety office or a company that sells PPE to find the right gloves and other PPE. o If exposure cannot be avoided during pregnancy, respirators can be worn to reduce the amount of certain chemicals that workers breathe in. Charcoal masks or surgical masks will not protect you from these chemicals. To be effective, respirators must be used correctly. Talk to your doctor and your employer if you think you might need to use a respirator. o Respirators are protective masks or hoods that you can wear to help you breathe cleaner air. There are many different types of respirators. Many respirators are unlikely to cause difficulties for pregnant workers, but there are a few things to consider:

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. Some respirators must be fitted to your face to make a tight seal. Weight changes, including weight gained during pregnancy, can affect how a respirator fits. If a respirator does not fit correctly, it may not protect you. . Some respirators (like negative pressure respirators) make you work harder to breathe. Because pregnancy can also make women work harder to breathe, this can sometimes cause difficulties (particularly late in pregnancy). If you wear a tight-fitting or negative pressure respirator, we suggest talking to your doctor and safety office to make sure you can wear your respirator safely and correctly throughout pregnancy. Pregnant women who have difficulty with their normal respirators might be able to switch job duties temporarily so they don’t have to wear a respirator, or switch to a different kind of respirator that doesn’t fit tightly to the face or make it more difficult to breathe. o Wear safety glasses and chemical aprons. o Wash any formaldehyde off your skin and change your clothes after work. o Open windows and doors, and use external ventilation systems to reduce the concentration of vapors in the room. o Clean drips and spills quickly using formaldehyde neutralization pads or sheets. o If you are working with tissues, cadavers, or animal specimens preserved using formalin, rinse the specimen in water to remove excess formalin before beginning dissection. Keep the formalin solution under a chemical fume hood or in another room while in the lab. o Some activities will have higher exposures than others. For example, dissections of the chest and abdomen appear to have higher levels of formaldehyde exposure. o Remove formaldehyde-contaminated waste from the work area and place it in sealed, labeled containers.

Responsibility

All faculty, staff and students engaged in the use or handling of formaldehyde (including dissection of embalmed cadaver) are responsible for understanding all hazards associated with its use, and for using appropriate work practices, engineering controls and personal protective equipment (PPE).

The Principle Investigator (PI) or faculty member is responsible for ensuring that his/her staff and students has been trained in the safe use and handling of formaldehyde. Use of formaldehyde is restricted to the specific staff members who have had training in proper use, handling and storage.

Training

Prior to conducting any work with formaldehyde, individuals will be trained to recognize the health hazards associated with formaldehyde, use appropriate engineering controls and use proper personal protective equipment (PPE).

Individuals working with formaldehyde shall receive a copy of these guidelines and Safety Data Sheets (SDSs) for formaldehyde. 14-3 Updated March 2017

Limiting Exposure to Formaldehyde

• Limit exposure to formaldehyde as much as possible. Limit physical contact with the cadaver and released liquids. Wear gloves, lab coat, safety glasses and shoe covers to prevent contamination of skin or clothing. Remove shoe covers and wash hands at end of class. • Avoid contamination of personal items. Store bags, purses in the lockers provided. Use book stands to hold dissection guide. Do not bring food or drink into the lab. • Suction excess fluids from the chest cavity with the supplied pump. Do not allow formaldehyde containing liquids to puddle on the floor. Absorb puddles with paper towels. Dispose of paper towels in the lidded trash container. Make sure the lid of the drain bucket located under the dissection table is closed. • Properly cover the cadaver after you finish. This will reduce the release of formaldehyde into the cadaver lab. • When not working with formaldehyde, avoid areas where formaldehyde is in use. • If possible, increase the distance between the source of exposure to formaldehyde and yourself. • Avoid loitering and eating near areas where formaldehyde is present.

Procedure

• Respirator use shall be permitted under the following circumstances: o During the interval necessary to install or implement feasible engineering and work practice controls. o In work situations where feasible engineering or work practice controls are not yet sufficient to reduce exposure below PEL/STEL. o In work situations where engineering controls and work practice controls are not feasible. o In emergencies where exposure could exceed PEL/STEL.

Whenever respirator use is required, employees and students shall be provided with an appropriate approved respirator at no cost and shall use it properly. The respirator selected shall reduce air-borne concentration of formaldehyde inhaled by the employee or student to at or below the TWA or STEL.

• Personal protective equipment (PPE) such as lab coats, gloves, goggles, face shields appropriate for use with formaldehyde, shall be provided at no cost to employees and students. The Supervisor shall ensure that employees and students: o Use appropriate PPE when working with formaldehyde. o Avoid contact of the eyes and skin with liquids containing one (1%) percent or greater formaldehyde by the use of chemical protective clothing made of material impervious to formaldehyde. o Use non-latex gloves, such as nitrile or butyl when handling HCHO.

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o Do not reuse PPE and clothing that has become contaminated with formaldehyde before it is cleaned or laundered. o Store contaminated equipment and clothing in containers labeled as: o Do not take home equipment or clothing contaminated with formaldehyde o Are trained properly before handling or removing formaldehyde contaminated clothing. o Are provided a room to change contaminated clothing, if needed. o Have access to working eyewash and emergency showers and are trained to use them in case of emergency. o Any person, who launders, cleans, or repairs HCHO contaminated clothing or equipment shall be informed of formaldehyde’s potentially harmful effects and procedures to safely handle such material.

Housekeeping

• The workplace shall be maintained clean and free from formaldehyde contaminated debris. • Formaldehyde contaminated debris and waste resulting from spills or other activities shall be placed for disposal in sealed container bearing label warning formaldehyde’s presence and its hazards. • Employees and students involved in clean up or maintenance should be informed about the hazards associated with formaldehyde exposure during such activities.

Hazard Communication

• All provisions of this program shall be enforced in all laboratories where formaldehyde is used. • Hazard warning labels that identify if the product contains formaldehyde shall be placed on the containers. • Labels shall inform users of “Potential Cancer Hazard”. • SDSs shall be made accessible to employees and students, when requested. • SDSs should be reviewed and updated, periodically

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ACKNOWLEDGEMENT:

I have read and understand these guidelines pertaining to the performance of duties involving potential exposure to formaldehyde. I am aware of the risks involved and will take the necessary precautions when working with formaldehyde.

SIGNATURE: ______

DATE: ______

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Appendix A Health Effects and Risks from Exposure to Formaldehyde

• Exposure to formaldehyde can cause lacrimation and wheezing.

• Working with formaldehyde may increase chances of having fertility problems, birth defects or a miscarriage. Most work exposures to formaldehyde are unlikely to be high enough to enter breast milk. However, formaldehyde may enter breast milk at exposure levels that are found in some workplaces, such as anatomy and mortuary science laboratories.

• Formaldehyde has been shown to be teratogenic in laboratory animals but human studies have been inconclusive. A teratogen is an agent or factor than can disturb the development of an embryo or fetus.

Limit exposure to formaldehyde as much as possible

• Limit physical contact with the cadaver and released liquids. Wear gloves, lab coat, safety glasses and shoe covers to prevent contamination of skin or clothing. Remove shoe covers and wash hands at end of class. • Avoid contamination of personal items. Store bags, purses in the lockers provided. Use book stands to hold dissection guide. Do not bring food or drink into the lab. • Suction excess fluids from the chest cavity with the supplied pump. Do not allow formaldehyde containing liquids to puddle on the floor. Absorb puddles with paper towels. Dispose of paper towels in the lidded trash container. Make sure the lid of the drain bucket located under the dissection table is closed. • Properly cover the cadaver after you finish. This will reduce the release of formaldehyde into the cadaver lab. • When not working with formaldehyde, avoid areas where formaldehyde is in use. • If possible, increase the distance between the source of exposure to formaldehyde and yourself. • Avoid loitering and eating near areas where formaldehyde is present.

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Please contact the Occupational and Environmental Safety Department located in Rowland Hall, Suite 307 for additional information at:

Extension: x6360 or x6150 Email: [email protected]

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Part 15. Mercury Spills: Cleanup and Safety

Philadelphia College of Osteopathic Medicine Occupational and Environmental Safety Department

All mercury spills shall be reported to the PCOM Occupational and Environmental Safety Department (x6360). Always call for assistance on how to properly clean up a mercury spill.

This document contains basic clean-up instructions for small liquid mercury spills. Table 1 has regional contacts and state guidelines for mercury spill management.

Mercury is toxic to the human nervous system. The developing brains of fetuses and infants are especially sensitive to mercury’s toxic effects. Mercury can be particularly hazardous because it can be easily absorbed through the lungs and into the bloodstream. Exposure to mercury vapors can occur when mercury products (such as thermometers and sphygmomanometers) are broken. Even very small amounts of mercury (several drops) may raise air concentrations to levels that may be harmful to human health.

Elemental mercury is a shiny liquid, silver-white in color and has many useful properties. It is the only metal that is liquid at room temperature. Mercury combines easily with other metals, is a good conductor of electricity and expands and contracts evenly with temperature changes. As a result, mercury has been used in many medical and industrial products such as thermometers and sphygmomanometers. Elemental mercury when spilled at room temperature can break up into small droplets and evaporate to form mercury vapor. The higher the room temperature the more mercury vapors will be released. Mercury vapors are also heavier than air and may linger in higher concentrations at the site of the spill.

CAUTIONS! NEVER touch mercury with bare hands. NEVER use a vacuum cleaner on a mercury spill, it will cause vaporization. NEVER use a broom to cleanup a mercury spill; it will cause the mercury to break up into smaller beads which will be difficult to collect. NEVER put mercury waste down the drain, in the trash or incinerator. NEVER use household cleaners to cleanup mercury spills.

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STEPS IN MERCURY SPILL CLEAN-UP

1. EVACUATE THE SPILL AREA: If people were in the room when the spill occurred, be sure that their shoes, clothing, and other articles have not been splashed with mercury before they leave the room. If mercury has contaminated any clothing or articles, remove these items from the person and place them in a plastic bag. Keep everyone else out of the spill area to prevent tracking. Keep the mercury from spreading into cracks, crevices, floor drains or onto sloped or porous surfaces, which are difficult to clean. If necessary, use masking tape or duct tape to make a vertical "fence" around the mercury droplets and confine them to a limited area for clean-up. If you cannot find the spilled mercury, consider the entire room contaminated and call for professional assistance.

2. LOWER the TEMPERATURE by turning down the thermostat. The cooler the temperature, the less mercury vapors will be released into the air. Mercury vapors are odorless and colorless.

3. TURN OFF CENTRAL VENTILATING OR AIR CONDITIONING SYSTEMS that could circulate air from the spill area to other parts of the building.

4. CLOSE INTERIOR DOORS leading to other rooms, but VENTILATE THE ROOM WITH THE SPILL TO THE OUTDOORS by opening windows and any exterior doors. Place fans, facing out, in open windows or doors to speed up ventilation, for 2 days if possible.

5. ASSEMBLE CLEAN-UP SUPPLIES: The following items may be helpful for safely cleaning up a small mercury spill. Assemble as many of them as you have. Remember that if the item comes in contact with mercury during the clean-up, it will have to be disposed of as hazardous waste: - Latex or rubber gloves - Goggles - Two small pieces of stiff paper or cardboard (not corrugated) with at least one straight edge, such as index cards or playing cards - Damp paper towels - Wide mouth plastic container with a lid - Airtight, sealable plastic bags - Garbage bags - Flashlight - Eyedropper - Tape – masking, duct, regular office – types & brands work differently, try many - Tweezers - Sulfur or zinc powder

Mercury spill kits with many of the items listed above are available from most laboratory and safety supply dealers. A mercury spill kit should be kept on the premises wherever mercury instruments are used. 15-2 Updated March 2017

6. DRESS APPROPRIATELY: Remove all jewelry from hands and wrists so the mercury does not bond to the metals. Change into old clothes and shoes that can be safely discarded if they become contaminated. Put on rubber gloves and goggles, if you have them.

Never use a vacuum cleaner to clean up mercury! Vacuum cleaners, even with filters, are not adequately filtered to remove mercury. Also they heat up and will spread mercury vapors. Once a vacuum has been contaminated with mercury, it will release mercury each time it is used; the only sure way to avoid spreading the contamination is to discard the vacuum cleaner.

Never use a broom on a mercury spill! It will contaminate the broom and only scatter the mercury droplets, making them harder to find and pick up.

Never pour mercury down the drain! You will contaminate your plumbing or your local sewage treatment plant. Never use household cleaning products because they may react violently with the mercury, releasing toxic gases.

7. PICK UP ALL VISIBLE MERCURY DROPLETS: For cleaning mercury from smooth, hard surfaces: If the mercury spill involves glass pieces, such as from a glass mercury thermometer, broken fluorescent or other mercury vapor containing lamps, or a glass ampoule from a mercury thermostat, use the tweezers to safely pick up any broken glass, placing the glass in the plastic container. Use the 2 pieces of stiff paper to push the mercury beads together and then scoop them up. Place the beads in the plastic container. (Alternatively, you can use a rubber squeegee and dust pan to collect the mercury beads, but you must dispose of these contaminated items afterwards.) Use an eyedropper to pick up the beads you can’t get with the cardboard. Hold the eyedropper almost parallel with the floor, or it will not work very well. Clear the eyedropper by gently squeezing the contents onto a damp paper towel. If you do not have an eyedropper, press the sticky side of the wide tape to the remaining beads. (Note: Tape only works on small beads of mercury, not large droplets.) When you think you’ve picked up all the mercury, shine a flashlight (at many different, low angles) on the area to find any remaining mercury beads or glass. Light will reflect off the mercury beads and glass helping you to locate them . For cleaning mercury from a carpet, rug or fabric: If the mercury spilled on a wall-to- wall carpet, cut out a section of the carpeting a bit larger than the mercury containing area to ensure that all the mercury is captured or call for assistance; see the contact information in Table 1.

For small rugs and other pieces of fabric, fold or roll the surface so that the mercury contaminated area is trapped inside. Place the contaminated rug or fabric in a sealable, plastic bag. If a sealable bag is not available or feasible to use, double- or triple-wrap

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the contaminated fabric in plastic trash bags. If the mercury spilled on a piece of fabric- covered furniture, call for assistance; see Table 1 for contacts.

8. SPRINKLE “FLOWERS OF SULFUR” (ELEMENTAL SULFUR IN POWDER FORM) OR FINE POWDER ZINC, if available, ON THE SPILL SITE: This will bind any remaining mercury. Apply over hard-to-reach areas, such as cracks and crevices, to bind the mercury and halt the release of mercury vapors. Afterwards, collect the powder with a moist paper towel and dispose of as mercury waste. Take care not to inhale sulfur powder and beware that it may permanently stain carpeting, clothing and furniture.

9. PLACE THE BROKEN PRODUCT AND ALL MATERIALS USED TO CLEAN UP THE MERCURY IN SEALABLE PLASTIC CONTAINERS OR AIRTIGHT, SEALABLE BAGS: This includes the cards, paper towels, eyedroppers, tweezers, and other equipment used to clean up the spill. Place the plastic containers or bags inside a second plastic container or bag to provide additional containment protection. Seal each bag or tighten each lid securely so that liquid and vapors will be contained. Consult Table 1 for disposal instructions in your state. If your state has a program for disposal of this type of waste, label the packages “Mercury Waste, Hazardous” and store in a secure place and in a ventilated area if possible until proper disposal can be arranged.

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AFTER YOU HAVE CLEANED UP THE SPILL:

1. CONTINUE VENTILATING the room or spill zone with outside air for a minimum of two days, if feasible. Fans to the outside will assist the ventilation. Now that the spill has been cleaned up, there is no longer a need to minimize vaporization by lowering the room temperature; warming the area during ventilation, if practical, will help dissipate any remaining mercury vapors more rapidly.

2. WASH HUMANS AND ANIMALS THAT CAME INTO CONTACT WITH MERCURY using soap and a paste of water and “flowers of sulfur,” if available. Afterwards, thoroughly rinse the area. Dispose of all clothing that may have come in contact with the mercury as mercury waste. NEVER PLACE MERCURY CONTAMINATED FABRICS IN A WASHING MACHINE or DRYER!

3. REPLACE THE BROKEN MERCURY DEVICE WITH A NON-MERCURY ALTERNATIVE. The best way to protect yourself from mercury exposure is to prevent spills from occurring.

4. TESTING RESIDUAL MERCURY: If you are uncertain about whether most of the spilled mercury was recovered and the room is frequented by small children or pregnant women, it may be wise to have the area tested for residual mercury in the air using a portable Jerome Meter or Lumex Mercury Analyzer. Some state environmental agencies have this capability. See Table 1 for state-specific contacts.

By federal law, manufacturing, educational and service facilities must report mercury spills greater than one pound (two tablespoons) to the proper authority. Therefore, a spill of this magnitude should be considered very serious. Some states advise getting professional assistance on spills that are greater than a few drops. If the mercury spill is on a porous surface such as a carpet, or if the mercury droplets are widely dispersed in a room, it would also be wise to call for professional assistance immediately. See Table 1 for a summary of states’ reporting requirements and assistance guidance for mercury spills.

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Table 1: Professional Assistance and Reporting Instructions

State Liquid Mercury Spill Guidelines Pennsylvania Contact the Department of Environmental Protection, (800) 541-2050, www.dep.state.pa.us Georgia Contact the Environmental Protection Division, Georgia Department of Natural Resources, Pollution Prevention Assistance Division, (404) 363-7026, (404) 651-5120

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Part 16. LAR Emergency Plan (Summary)

Philadelphia College of Osteopathic Medicine Occupational and Environmental Safety Department

Summary: The LAR Emergency Plan is a self-contained supplement to the PCOM EMERGENCY PREPAREDNESS GUIDELINES. It describes the steps to be taken in case of a disaster which may disturb the health and/or safety of personnel engaged in animal activities at PCOM. The likely disasters that could occur include floods, fire, smoke, and major power failures, but other unanticipated events are possible.

The entire Plan may be found in the complete PCOM Safety Manual on my.pcom.edu.

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Part 17a. DOT Security Plan for PCOM-GA Campus

• Control access to hazardous materials and keep a strict inventory. Lock laboratory doors when the room is unoccupied and maintain control of hazardous materials and wastes. Such control is typically maintained through use of locking freezers, flammable cabinets or other laboratory storage equipment. Limit access to labs by unauthorized personnel.

o This is fulfilled through having locked flammable cabinets with written lists of chemicals outside each cabinet. Each cabinet is separated by acids, bases, liquids, solids, oxidizers and reducers. On the outside of the lab, an inclusive chemical list with the location of each chemical is posted. The hazardous chemicals (determined by their NFPA rating) are all stored in our flammable cabinets and listed at the top of the main chemical listing. These lists are updated every 6 months and the keys are located in a locked room and on the lab technician’s key ring. The locked room is only accessible by people who have completed the lab safety training.

• If you solicit the transportation of hazardous materials by an outside party (courier, air freight company, etc.), verify the identity of the driver before releasing the materials. Make sure the shipment is properly packaged and labeled prior to releasing.

o Pharmacy must call the DOT Hazardous Materials Information Center (1-800- 467-4922) with packaging information before shipping blood components.

• When transporting hazardous materials across campus, minimize exposure to classrooms, offices, and other public areas by taking less populated paths or roads. Never leave hazardous materials unattended while in transit.

o This school has a back hallway that is not open to the public that the labs are allowed to use to bring in shipments that they receive from companies.

• Report suspicious incidents or events involving hazardous materials or storage areas. Make sure your staff and coworkers are aware of security procedures.

o We have a small number of people that are allowed to be in the lab space and all of these people are required to do safety training before being allowed to work in the lab. Security also patrols every hour (this is documented by Security).

• Promptly report any missing hazardous materials to the police.

o Any incidence of missing chemicals must be reported to campus security who would then in turn report to the main campus in Philadelphia for processing. We have security cameras posted outside of the labs which can be pulled up on the main campus for investigation.

17a-1 Updated March 2017 Part 18. Confined Spaces Safety Program

Philadelphia College of Osteopathic Medicine Occupational and Environmental Safety Department

Confined Spaces Safety Program SCOPE: The purpose of the Philadelphia College of Osteopathic Medicine’s (PCOM) Confined Spaces Safety Program is to protect employees, contractors and students against the hazards involved in confined spaces. Further, this procedure establishes the controls and responsibilities for entering, working in, and exiting confined spaces while complying with OSHA CFR 1910.146. This program covers all PCOM employees, contractors and students on campus who are required to enter confined spaces that may potentially contain hazardous atmospheres or conditions. A workplace evaluation has determined that the following locations are Confined Spaces:

• All manholes on campus • All pits for incoming water services • All elevator pits • All freezer rooms • All IT rooms PCOM employees and students will not enter manholes on campus, pits for incoming water services and elevator pits. Only contractors will be entering these confined spaces. It is the responsibility of Plant Operations when hiring contractors to confirm that contractors have their own confined spaces safety program. PCOM employees and students will only enter freezer rooms in order to pick up and drop off biological samples in the freezers. Any work on the samples will not take place in the freezer rooms. Freezer rooms are not considered permit required confined spaces. PCOM employees will only enter IT rooms to perform servicing duties. Routine IT office duties shall not take place in IT rooms. DEFINITIONS: Confined Space – a confined space has limited or restricted means of entry or exit, is large enough for an employee to enter and perform assigned work, and is not designed for continuous occupancy by the employee. Acceptable entry conditions – the conditions that must exist in a permit space to allow entry and to confirm that employees involved with a permit-required confined space entry can safely enter into and work within the space.

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Attendant – an individual stationed outside one or more permit spaces who monitors authorized entrants and who performs all attendant’s duties assigned in the employer’s permit space program. Authorized entrant – an employee who is authorized by the employer to enter a permit space. Entry – the action by which a person passes through an opening into a permit-required confined space. Entry includes ensuing work activities in that space and is considered to have occurred as soon as any part of the entrant’s body breaks the plane of an opening into the space. Entry permit – the written or printed document that is provided by the employer to allow and control entry into a permit space. Entry supervisor – the person (such as the employer, foreman, or crew chief) responsible for determining if acceptable entry conditions are present at a permit space where entry is planned, for authorizing entry and overseeing entry operations, and for terminating entry as required by this section. Hazardous Atmosphere – an atmosphere that may expose employees, contractors or students to the risk of death, incapacitation, interfere with an individual’s ability to escape unaided from a space, or cause acute illness from one or more of the following causes: Flammable gases, vapors or mists in excess of five percent (5%) of its Lower Explosion Limit (LEL). Atmospheric oxygen concentrations below 19.5% or above 23.5%$. Atmospheric concentrations of any substance that could meet or exceed the permissible exposure limit (PEL) as prescribed by the Occupational Safety & Health Administration’s (OSHA) standards. Any other atmospheric condition that is immediately dangerous to life or health (IDLH). Immediately dangerous to life or health (IDLH) – any condition that poses an immediate or delayed threat to life or that would cause irreversible adverse health effects or that would interfere with an individual’s ability to escape unaided from a permit space. Isolation – the process by which a permit space is removed from service and completely protected against the release of energy and material into the space by such means as: blanking or blinding; misaligning or removing sections of lines, pipes or ducts; a double block and bleed system; lockout or tagout of all sources of energy; or blocking or disconnecting all mechanical linkages. Non-Permit Confined Space – a Confined Space which does not contain or have the potential to contain a “Hazardous Atmosphere” or any hazard capable of causing death or serious physical harm. Permit Required Confined Space (PRCS) – a Confined Space that has one or more of the following characteristics:

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• Contains or has the potential to contain a “Hazardous Atmosphere” • Contains a material with the potential for engulfment of an entrant • Has an internal configuration such that an entrant could be trapped or asphyxiated by inwardly converging walls, or a floor which slopes downward and tapers to a smaller cross-section • Contains any other recognized serious safety or health hazard Any space meeting the above definition will be entered by permit only. CLASSIFICATION: Confined spaces may be classified into two categories 1. Open-topped enclosures with depths that restrict the natural movement of air (e.g., degreasers, pits, selected types of tanks and excavations), and 2. Enclosures with limited openings for entry and exit (e.g., sewers, tanks, freezer rooms and silo). RESPONSIBILITIES: The Chief Occupational/Environmental Safety Officer:

• Shall confirm that PCOM personnel maintain compliance with the Confined Spaces Safety Program • Shall confirm that only trained employees assume roles and perform work in confined spaces in accordance with this program • Confirms that an annual review of the overall effectiveness of the Confined Spaces Program is conducted • Train employees for confined space operations Assistant Director Plant Operations & Entry Supervisors:

• Are responsible for initiating and controlling this procedure on shift. • Confirm that the proper procedures for isolating all energy sources are followed and that all energy sources have been controlled. • Confirm inspection of work in spaces to adhere to procedures • Be trained to be aware of hazards of the space to be entered, and signs, symptoms, and consequences of exposure and specific space control procedures • Execute all requirements of this instruction before work begins within a confined space • Authorize entry into a confined space when acceptable entry conditions have been met • Confirm that all personnel entering and leaving the confined space are accounted for Entrants:

• Be trained to know the hazards that may be faced during entry, including information on the mode, signs or symptoms and consequences of the exposure. • Communicate with the attendant as necessary to enable the attendant to alert entrants of the need to evacuate the space as required by this instruction and for attendant to be able to monitor status of entrants. 18-3 Updated April 2017

• Alert the attendant whenever: o The entrant recognizes any warning sign or symptom of exposure to a dangerous situation or o The entrant detects a prohibited condition • Exit from the confined space as quickly as possible whenever: o Order to evacuate is given by the attendant or the entry supervisor. o The entrant recognizes any warning sign or symptom of exposure to a dangerous situation, or the entrant detects a prohibited condition or an evacuation alarm is activated. Attendants:

• Be trained to know the hazards that may be faced during entry, including information on the mode, signs or symptoms and consequences of exposure • Be aware of the possible behavioral effects of hazardous exposure in authorized entrants • Continuously maintain an accurate count of authorized entrants in the permit space and confirm that the means used to identify authorized entrants in the permit under this procedure is accurate • Remain outside the permit space during entry operations until relieved by another attendant. Attendants shall never monitor more than one Confined Space. • Communicate with authorized entrants as necessary to monitor entrant status and to alert entrant of the need to evacuate the space if conditions warrant. • Initiate onsite rescue procedures and if necessary, summon additional rescue and other emergency rescue services when self-rescue is not possible. • Perform no duties that might interfere with his/her ability to monitor and protect the authorized entrants. • Monitor activities inside and outside the space to determine if it is safe for entrants to remain in the space. • Warn unauthorized persons to stay away and advise those who may have entered the permit space that they must leave. • Inform authorized entrants, Assistant Director Plant Operations and Entry Supervisor of unauthorized persons. GENERAL INFORMATION: General Rules:

• When practical, all permit required confined spaces shall be permanently marked. A sign shall be installed at each opening of the permit required confined space. Signs should contain the following text or similar language:

DANGER – PERMIT REQUIRED CONFINED SPACE DO NOT ENTER

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Spaces not permanently marked (ex. manholes) shall be posted with a portable sign when access to the spaces is required.

• All confined spaces where there is an opening that can easily be walked into (floor openings, manhole openings, etc.) shall have a physical barrier (guardrail, gate, etc). • When required, isolating energy sources to the confined space shall be performed in accordance with PCOM’s Lockout/Tagout Program. • If “hot work” conditions exist, precautions shall be taken in accordance with PCOM’s Hot Work Operations Safety Program. Cylinders of compressed gases are never permitted in a confined space. • No smoking is permitted in a Confined Space or near the entrance/exit area. • Portable electrical equipment used in Confined Spaces, which have wet surfaces, shall be supplied power through a ground fault interrupter or be battery powered.

Confined Space Personnel - The following individuals are required when entry into a PRCS is necessary. Employees shall receive the appropriate level of training before entry into the Confined Space is permitted. Note: An attendant can also act as an entry supervisor if properly trained.

• Assistant Director Plant Operations/Entry Supervisor • Attendant • Entrant(s) PROCEDURE: Confined Space Entry Permit

• Before entry is authorized, the entry supervisor shall document the safety measures taken in order to enter the PRCS by preparing a Confined Space Entry Permit. Before entry begins, the entry supervisor identified on the permit shall complete and sign the entry permit to authorize entry. Acceptable entry conditions must be met in order for entry to be authorized. • The completed permit shall be made available at the time of entry to all authorized entrants, by posting it at the entry portal or by any other equally effective means; so that the entrants can confirm that pre-entry preparations have been completed. • The duration of the permit may not exceed the time required to complete the assigned task, the job identified on the permit or one work shift. • The entry supervisor shall terminate entry and cancel the entry permit when: o The entry operations covered by the entry permit have been completed or o A condition that is not allowed under the entry permit arises in or near the permit space. • Canceled entry permits shall be retained, by the Occupational/Environmental Safety Department for at least one year to facilitate the review of the PRCS program. Any

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problems encountered during an entry operation shall be noted on the pertinent permit so that appropriate revisions to the program can be made.

Entry Procedures Prior to entry into a confined space, The Entry Supervisor will conduct a job review to discuss the safe entry procedures with the personnel involved. The required equipment will be assembled and instructions will be conveyed to those involved in the entry; procedures will be discussed; and hazards, which may be encountered, will be explained. The Confined Space Hazard Evaluation contained in Attachment A must be reviewed and the acceptable entry conditions must be met in order for entry to be authorized:

• Specifying acceptable entry conditions, • Isolating the permit space, • Purging, flushing, or ventilating the permit space as necessary to eliminate or control atmospheric hazards, • Providing pedestrian, vehicle, or other barriers as necessary to protect entrants from external hazards and • Verifying that conditions in the permit space are acceptable for entry throughout the duration of an authorized entry.

Retrieval and rescue equipment is required for entry into the permit required confined spaces. The use of a harness is not required if it will create a greater hazard to the wearer. CONTRACTORS: At a minimum, contractors must follow the requirements of OSHA’s Confined Space requirements PCOM will provide contractors: information on all PRCS to be entered and the potential hazards associated with the Confined Space. Contractor employees must be trains in confined space entry. Contractors that are required to enter a Confined Space must attest that their employees have been trained in accordance with 29 CFR 1910.146. PCOM’s Contractor Representative will communicate to the contractor, the requirements of this program and potential hazards they may encounter inside the confined space and the surrounding area. Contractor training should be documented. PCOM will coordinate efforts any time an employee and a contractor(s) employee(s) are simultaneously entering a space. If multiple contractors/employees are going to be occupying the same area, the following shall take place:

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• A pre-job briefing shall be conducted involving all pertinent work groups. This briefing shall include the requirement of a separate air monitoring and permitting for each contractor, means to prohibit unauthorized/accidental entry, known hazards associated with the space, means to abate those hazards, and procedures for emergency response. • A review of PCOM’s Lockout/Tagout Program and requirements for its use. • Identification of Assistant Director Plant Operations, Attendants and Entrants. • Means of communication among work groups, including signaling for evacuation. • A collective debriefing among all work groups at the closing of each permit day. CONFINED SPACE RESCUE: In the event of an emergency of any type in the confined space, entrants in the space shall evacuate as quickly as possible. Injured employees are encouraged to use self-rescue when applicable. If rescue from within the confined space is required, the attendant should immediately call PCOM Security at 215-871-6911 or 911 from a cell phone. Inform PCOM Security or 911 phone operator the location, type of confined space and the hazards associated with the space. After a rescue response is confirmed, the attendant shall notify their supervisor or the Occupational and Environmental Safety Department located in Suite 307 Rowlands Hall or by dialing extension x6360 or x6150. Under no circumstances will a Confined Space Attendant enter a confined space during rescue. Their responsibility is to ensure that the rescue team arrives at the correct location and receives all information regarding the confined space and the circumstances surrounding the need for rescue. Rescue personnel shall follow their own procedures for confined space entry. TRAINING: All personnel involved with confined space activities shall receive training consistent with their duties. Employees will receive training in order to acquire the understanding, knowledge and skills necessary for the safe performance of the duties assigned under this program. Training shall be provided to each affected employee that may be designated as an entrant or attendant:

• Before the employee is first assigned duties • Before there is a change in assigned duties • Whenever there is a change in confined space operations which presents a hazard to an employee who has not been previously trained and • Whenever the employer has reason to believe that there are deviations from the confined space entry procedures or that there are inadequacies in the employee’s knowledge or use of these procedures. • The training shall establish employee proficiency in the duties required and shall introduce new or revised procedures, as necessary, for compliance.

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Training content shall include:

• Duties of Assistant Director Plant Operations and Entry Supervisor, Entrants and Attendants • PCOM’s Confined Spaces Program • Hazards of Confined Spaces • Use of Air Monitoring Equipment • Use of ventilation equipment • Emergency Action and Rescue Procedures • Confined Space Entry Equipment, including Personal Protective Equipment • Requirements of 29 CFR 1910.146 Permit Required Confined Spaces DOCUMENTATION:

• Training documentation shall be kept for all affected employees. Training rosters shall indicate the employee’s name, date, level of training (supervisor, entrant, attendant). The Occupational/Environmental Safety Department shall maintain all training records • The Confined Space Procedure will be reviewed annually or when PCOM has reason to believe that measures taken may not protect employees or contractors that enter a space

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Part 19. Lockout/Tagout Safety Program

Philadelphia College of Osteopathic Medicine Occupational and Environmental Safety Department

LOCKOUT/TAGOUT SAFETY PROGRAM Scope: The Lockout/Tagout (LOTO) program is designed for employees to place machinery, equipment or systems that are capable of causing injury by energizing, unexpected starting or releasing stored energy into a safe condition and that the safe condition is maintained for the duration of the task. This program applies to all Philadelphia College of Osteopathic Medicine employees. Effective hazardous energy control procedures will protect all workers potentially exposed to unexpected energizing or release of stored energy that could cause injury to employees during the servicing or maintenance of machines, equipment or systems, as well as while working on or near exposed de-energized electrical conductors and parts of electrical equipment. The LOTO standard applies to general industry employment and covers the servicing and maintenance of machines and equipment in which the unexpected start-up or the release of stored energy could cause injury to employees. The LOTO procedure meets the requirements specified by the Occupational Safety and Health Administration (OSHA) 29 CFR 1910.147, Control of Hazardous Energy (LOTO); 29 CFR 1910.333, Lockout/Tagout Electrical Safe Work Practices; and 1926.417, Lockout and Tagging of Circuits, as they relate to the control of hazardous energy sources. Definitions:

Affected Employee- An employee whose job requires him/her to operate or use a machine, equipment or system on which servicing or maintenance is being performed under LOTO or whose job requires him or her to work in an area in which such servicing or maintenance is being performed.

Authorized Employee- A person who either applies the locks and tags on machines, equipment and systems or works under the protection of LOTO in order to perform servicing or maintenance on that machine or equipment. This person has completed the mandatory training to be qualified as an Authorized Employee. Only an authorized employee installs and removes his or her own lock(s) and tag(s) as required by this program.

Authorized Locks and Tags - These are locks and tags that are used to ensure the safety of the authorized employees performing servicing and maintenance of machines, equipment or systems. Servicing or maintenance may not begin until these devices are applied to the energy isolation device(s). These locks and tags shall not be used for any other purpose. The locks shall be

19-1 Updated April 2017 singularly keyed and the authorized employees shall retain the keys to individual locks. The print and format of tags shall be standardized and will warn against hazardous conditions if the machine, equipment or system is energized. The tag shall read “Danger – Do Not Operate” and will have black lettering with a white background. The tag will have an unlocking strength of at least 50 pounds. Locks and tags will identify the authorized employee applying the devices. Only an authorized employee may perform service or maintenance work on the machine, equipment or system.

Energy Source - Any source of hazardous energy or materials. Energy sources include, but are not limited to; electrical, mechanical, hydraulic, pneumatic, chemical, radiation, and thermal energies, as well as various forms of potential energy such as that stored in springs, compressed gases, or in suspended objects (gravitational).

Double Block and Bleed - The closure of a line, duct, or pipe by closing and locking and tagging two in-line valves and by opening and locking/tagging a drain or vent in the line between the two closed valves.

Energy Isolation Device - A device that prevents the transmission or release of hazardous energy or hazardous materials. Examples include, but are not limited to; restraint blocks, electrical circuit breakers, disconnect switches, slide gates, slip blinds, or line valves. For lockout/tagout purposes, isolating devices that provide visible indication of the device’s position are desirable.

Lockout Device - A device that utilizes a positive means such as a lock, either keyed or combination type, to hold an energy-isolating device in a safe position to prevent the energizing of a machine, equipment or system. Other lockout devices include dead ends (blanks), bolted slip blinds, valve hand wheel covers, and chains/lock. All locks require a Danger Tag.

Lockout/Tagout (LOTO) - Installation of lock(s) and tag(s) on the Energy Isolation Devices to ensure that the task can be performed safely. The lock(s) and tag(s) ensure that the Energy Isolating Device(s) and the machine, equipment or system they isolate and/or control, cannot be operated until the lock(s) and tag(s) are removed.

Other Employees - Employees whose work operations are or may be in an area where energy control procedures are utilized.

Safe Condition Check (Verification of De-energizing) - The inspection or test of a machine, equipment or system performed by the Authorized Employee to ensure that the hazardous energy or materials are controlled to prevent injury or accident. Note: This is an essential element of all energy control programs and procedures, which ensures the safety of all potentially exposed personnel.

Maintenance and/or Construction - Workplace activities such as maintenance inspections, construction, installing, setting up, modifying, adjusting, and maintaining and or servicing machines, equipment or systems. These activities include lubrication, cleaning, or un-jamming of

19-2 Updated April 2017 machines or equipment and making adjustments or tool changes, where the employee may be exposed to the unexpected energizing or start-up of the equipment or release of hazardous energy. This applies to all personnel regardless of job title; (i.e., operator, maintenance, electrician, etc.)

Tag - A “Danger – Do Not Operate” Tag, which can be securely fastened to an energy isolating device with an unlocking strength of 50 pounds, to indicate that the energy isolating device and the machine, equipment or system being controlled cannot be operated until the tag is removed. Tags are essentially warning devices affixed to energy isolating devices and do not provide the physical restraint of a lock.

Supervisor – One who has the responsibility of overseeing lockout/tagout activities.

Responsibilities:

The Chief Occupational/Environmental Safety Officer and the Chief Compliance Officer - is responsible for approving and enforcing compliance with this procedure.

Supervisors - are responsible for initiating and controlling this procedure. Ensure that the proper procedures for isolating all energy sources have been implemented. Identify personnel required to complete Penn’s Control of Hazardous Energy (Lockout/Tagout) training.

Authorized Employees - are responsible for isolating all energy sources to a machine, equipment or system and ensuring a safe condition before work is performed. Inspects machine, equipment or system to ensure that all energy has been isolated, energy dissipated and installs authorized locks & tags.

Procedure:

The procedure for apply LOTO devices at PCOM are as follows:

1. Notify affected employees of shutdown

2. Prepare for shutdown (i.e. locks, tags, ladders, tools)

3. Shutdown the machine, equipment or service

4. Apply the LOTO device

5. Render safe all stored or residual energy (i.e. depressurize)

6. Verify the isolation and de-energization of the machine, equipment or service

7. Log LOTO devices that exceed your shift in the PCOM, Critical Equipment Area Log

19-3 Updated April 2017 Removal of Locks and Tags:

The procedure for removing locks and tags at PCOM are as follows:

1. Notify affected employees the machine, equipment, or service is being restored

2. Inspect the work area to confirm that non-essential items have been removed and that machine, equipment or service components are intact and capable of operating properly

3. Remove locks and tags and return machine, equipment or service to operation

4. Verify all aspects of machine, equipment or service is operating properly

5. Return locks and tags to LOTO station

6. Log LOTO device removal in the PCOM, Critical Equipment Area Log

Contractors:

PCOM and the outside contractor must inform each other of their respective control of LOTO procedures. The responsibility for training outside contractor employees lies with their employer. PCOM shall ensure that its employees understand and comply with the restrictions and prohibitions of the outside employer’s LOTO program. Prior to the contractor performing work, a designated point of contact will be made within the contractor’s organization for the purpose of interfacing and coordinating the control of LOTO procedures.

LOTO Periodic Inspections:

• PCOM shall perform an annual review of its LOTO program and procedures for confirming that the requirements of 29 CFR 1910.147 (The Control of Hazardous Energy [lockout/tagout] are being met). A written report shall be made documenting inspection findings, results, and as appropriate any corrective actions taken for LOTO program deficiencies. • Periodic inspections of PCOM’s LOTO Program and procedures shall be conducted at least annually. • Periodic inspections shall be scheduled and documented in writing. • A person trained as an authorized employee must perform the periodic inspection. The representative may not review any LOTO task that they currently have responsibility for. The representative must review the procedures being implemented by and under the control of other authorized employees. The inspection shall include a review of each authorized employee’s responsibilities under the program and related procedures. • An inspection of various LOTO tasks that have been closed out will be inspected to verify that they have been properly completed and closed out. • Active control of LOTO tasks will be visually verified to confirm that all locks and tags are in place. The required LOTO documents will be verified to have been prepared in accordance with PCOM’s LOTO Program.

19-4 Updated April 2017 • If during the inspection a discrepancy or procedural inadequacy is found, steps shall be taken immediately to determine the reason for, and the corrective action necessary to remedy the discrepancy. • Discrepancies or noncompliance with PCOM’s LOTO Program and procedures will be corrected as soon as possible but no later than 60 days from the date of identification. The appropriate individuals shall be retrained if a discrepancy or inadequacy is identified. Personnel LOTO Training:

• Employees shall be trained so that they understand the purpose and function of the LOTO program and procedures. Employees shall also be trained so that they understand the purpose, contents and requirements of 29 CFR 1910.147, The Control of Hazardous Energy (Lockout/Tagout). • Authorized Employees shall receive training in the recognition of sources of hazardous energy, the types and magnitude of hazardous energy and the means and methods of isolation and control. • Affected Employees shall be instructed in the purpose and use of the PCOM’s LOTO Program. • Other Employees shall be instructed about PCOM’s LOTO Program and about the prohibition against attempting to restart equipment, machines or systems that have been locked and tagged out of service. • Employee retraining will be conducted when there are changes in job assignment; machines, equipment or processes; or in PCOM’s LOTO Program and procedures. Retraining will also be conducted when a periodic inspection of the effectiveness of this procedure reveals inadequacies in employee knowledge or performance. • A record of all training and retraining shall be maintained. PCOM utilizes computer- based training modules annually for employees.

Recordkeeping:

The Chief Occupational/Environmental Safety Officer will maintain LOTO Program training records and periodic inspections on file.

Conclusion:

PCOM locks, hasps and tags are located in Central Plant at the designated LOTO station. Locks are color coded red. Tags are designated “DANGER DO NOT OPERATE.” These procedures provide the tools necessary to work safely around hazardous energy sources. All employees and contractors must follow these procedures to prevent injuries.

Contact the Chief Occupational/Environmental Safety Officer at email: occ-env- [email protected]

19-5 Updated April 2017