DOCSLIB.ORG

Colorectal Liver Metastases: Current Management and Future Perspectives

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Colorectal Liver Metastases: Current Management and Future Perspectives World Journal of W J C O Clinical Oncology Submit a Manuscript: https://www.f6publishing.com World J Clin Oncol 2020 October 24; 11(10): 761-808 DOI: 10.5306/wjco.v11.i10.761 ISSN 2218-4333 (online) REVIEW Colorectal liver metastases: Current management and future perspectives Jack Martin, Angelica Petrillo, Elizabeth C Smyth, Nadeem Shaida, Samir Khwaja, HK Cheow, Adam Duckworth, Paula Heister, Raaj Praseedom, Asif Jah, Anita Balakrishnan, Simon Harper, Siong Liau, Vasilis Kosmoliaptsis, Emmanuel Huguet ORCID number: Jack Martin 0000- Jack Martin, Raaj Praseedom, Asif Jah, Anita Balakrishnan, Simon Harper, Siong Liau, Vasilis 0001-9545-0298; Angelica Petrillo Kosmoliaptsis, Emmanuel Huguet, Department of Surgery, Addenbrookes Hospital, NIHR 0000-0001-5489-5733; Elizabeth C Comprehensive Biomedical Research and Academic Health Sciences Centre, Cambridge Smyth 0000-0002-4667-1817; Nadeem University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, United Kingdom Shaida 0000-0002-6843-7458; Samir Khwaja 0000-0002-2481-6800; HK Angelica Petrillo, Department of Precision Medicine, Division of Medical Oncology, University Cheow 0000-0002-2334-3597; Adam of Campania "L. Vanvitelli", Napoli 80131, Italy, & Medical Oncology Unit, Ospedale del Duckworth 0000-00028664-4987; Mare, 80147 Napoli Italy Paula Heister 0000-0001-7207-869X; Raaj Praseedom 0000-0001-9541- Elizabeth C Smyth, Department of Oncology, Addenbrookes Hospital, NIHR Comprehensive 6356; Asif Jah 0000-0001-5541-1550; Biomedical Research and Academic Health Sciences Centre, Cambridge University Hospitals Anita Balakrishnan 0000-0001-6406- NHS Foundation Trust, Cambridge CB2 0QQ, United Kingdom 6066; Simon Harper 0000-0001-6016- 8049; Siong Liau 0000-0001-5155- Nadeem Shaida, Samir Khwaja, Department of Radiology, Addenbrookes Hospital, NIHR 4300; Vasilis Kosmoliaptsis 0000- Comprehensive Biomedical Research and Academic Health Sciences Centre, Cambridge 0001-7298-1387; Emmanuel Huguet 0000-0001-5816-5308. University Hospitals NHS Foundation Trust, Cambridge CB22 0QQ, United Kingdom Author contributions: Martin J HK Cheow, Department of Nuclear Medicine, Addenbrookes Hospital, NIHR Comprehensive designed the structure of the Biomedical Research and Academic Health Sciences Centre, Cambridge University Hospitals overall manuscript and authored NHS Foundation Trust, Cambridge CB2 0QQ, United Kingdom text in all sections; Petrillo A and Adam Duckworth, Paula Heister, Department of Pathology, Addenbrookes Hospital, NIHR Smyth EC authored text in the Comprehensive Biomedical Research and Academic Health Sciences Centre, Cambridge chemotherapy sections; Shaida N University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, United Kingdom authored text in the interventional radiology sections; Khwaja S Corresponding author: Emmanuel Huguet, BSc, DPhil, FRCS, MBChB, Surgeon, Surgical authored text in imaging sections; Oncologist, University Department of Surgery, Addenbrookes Hospital, NIHR Comprehensive Cheow H authored text in the Biomedical Research and Academic Health Sciences Center, Cambridge University Hospitals nuclear medicine section; NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, United Kingdom. Duckworth A and Heister P [email protected] authored text in the pathology section; Praseedom R, Jah A, Balakrishnan A, Harper S, Liau S Abstract and Kosmoliaptsis V authored text The liver is the commonest site of metastatic disease for patients with colorectal in the surgery sections; Huguet E cancer, with at least 25% developing colorectal liver metastases (CRLM) during designed the structure of the the course of their illness. The management of CRLM has evolved into a complex overall manuscript and authored field requiring input from experienced members of a multi-disciplinary team text in all sections. All authors WJCO https://www.wjgnet.com 761 October 24, 2020 Volume 11 Issue 10 Martin J et al. Colorectal liver metastase have read and approved the final involving radiology (cross sectional, nuclear medicine and interventional), manuscript. Oncology, Liver surgery, Colorectal surgery, and Histopathology. Patient management is based on assessment of sophisticated clinical, radiological and Conflict-of-interest statement: All biomarker information. Despite incomplete evidence in this very heterogeneous other authors have nothing to patient group, maximising resection of CRLM using all available techniques disclose. remains a key objective and provides the best chance of long-term survival and cure. To this end, liver resection is maximised by the use of downsizing Open-Access: This article is an chemotherapy, optimisation of liver remnant by portal vein embolization, open-access article that was associating liver partition and portal vein ligation for staged hepatectomy, and selected by an in-house editor and combining resection with ablation, in the context of improvements in the fully peer-reviewed by external functional assessment of the future remnant liver. Liver resection may safely be reviewers. It is distributed in carried out laparoscopically or open, and synchronously with, or before, accordance with the Creative colorectal surgery in selected patients. For unresectable patients, treatment Commons Attribution options including systemic chemotherapy, targeted biological agents, intra- NonCommercial (CC BY-NC 4.0) arterial infusion or bead delivered chemotherapy, tumour ablation, stereotactic license, which permits others to radiotherapy, and selective internal radiotherapy contribute to improve survival distribute, remix, adapt, build and may convert initially unresectable patients to operability. Currently evolving upon this work non-commercially, areas include biomarker characterisation of tumours, the development of novel and license their derivative works systemic agents targeting specific oncogenic pathways, and the potential re- on different terms, provided the emergence of radical surgical options such as liver transplantation. original work is properly cited and the use is non-commercial. See: htt Key Words: Colorectal; Cancer; Liver; Metastases; Management; Review p://creativecommons.org/licenses /by-nc/4.0/ ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. Manuscript source: Invited manuscript Core Tip: The management of colorectal liver metastases is a complex evolving field requiring input from an experienced multi-disciplinary team involving radiology (cross Received: February 27, 2020 sectional, nuclear medicine and interventional), Oncology, Liver surgery, Colorectal Peer-review started: February 27, surgery, and Histopathology. Patient management is based on clinical, radiological and 2020 biomarker information. Despite incomplete evidence in this very heterogeneous patient First decision: April 7, 2020 group, maximising resection of colorectal liver metastases using all available techniques Revised: May 14, 2020 remains a key objective and provides the best chance of long-term survival. For Accepted: August 31, 2020 unresectable patients, optimal systemic and locoregional chemotherapeutic, biological and Article in press: August 31, 2020 radiotherapeutic treatments improve survival, and may convert initially unresectable Published online: October 24, 2020 patients to operability. P-Reviewer: Fan H, Mikulic D, Romani A Citation: Martin J, Petrillo A, Smyth EC, Shaida N, Khwaja S, Cheow H, Duckworth A, Heister S-Editor: Zhang L P, Praseedom R, Jah A, Balakrishnan A, Harper S, Liau S, Kosmoliaptsis V, Huguet E. Colorectal liver metastases: Current management and future perspectives. World J Clin Oncol L-Editor: A 2020; 11(10): 761-808 P-Editor: Li JH URL: https://www.wjgnet.com/2218-4333/full/v11/i10/761.htm DOI: https://dx.doi.org/10.5306/wjco.v11.i10.761 INTRODUCTION Colorectal cancer (CRC) represents a major worldwide health care burden, as the second most common cancer diagnosed in women and third most common in men, and accounting for 10% of all annually diagnosed cancers and cancer-related deaths worldwide[1]. As result of improvements in detection through screening[2], better referral pathways[3], centralisation of services[4], effective primary surgery[5], development of systemic chemotherapy[6], biological agents[7], and understanding of tumour biology[8], survival rates following diagnosis have improved[9]. Nevertheless, at least 25%-50% of patients with CRC develop colorectal liver metastases (CRLM) during the course of their illness. From a historical perspective, the surgical management approach to CRLM has undergone a significant evolution. Starting from an era prior to the 1930s during which liver surgery for malignancy presented insurmountable challenges for technical and oncological reasons, tentative attempts at liver resection for malignancy were WJCO https://www.wjgnet.com 762 October 24, 2020 Volume 11 Issue 10 Martin J et al. Colorectal liver metastase made in the subsequent decades resulting in early reports establishing proof of principle that long term survival following resection of CRLM was possible[10,11]. These results were confirmed and emphasised by larger landmark studies firmly establishing liver surgery as a potentially curative treatment for CRLM[12,13]. The era since has been characterised by progress in understanding of tumour biology as well as surgical and oncological developments. These overlapping and interdependent factors have directed the modern management of CRLM to a multidisciplinary approach involving radiology (cross sectional, nuclear
Load more

Recommended publications
  • Aalseth Aaron Aarup Aasen Aasheim Abair Abanatha Abandschon Abarca Abarr Abate Abba Abbas Abbate Abbe Abbett Abbey Abbott Abbs
    BUSCAPRONTA www.buscapronta.com ARQUIVO 35 DE PESQUISAS GENEALÓGICAS 306 PÁGINAS – MÉDIA DE 98.500 SOBRENOMES/OCORRÊNCIA Para pesquisar, utilize a ferramenta EDITAR/LOCALIZAR do WORD. A cada vez que você clicar ENTER e aparecer o sobrenome pesquisado GRIFADO (FUNDO PRETO) corresponderá um endereço Internet correspondente que foi pesquisado por nossa equipe. Ao solicitar seus endereços de acesso Internet, informe o SOBRENOME PESQUISADO, o número do ARQUIVO BUSCAPRONTA DIV ou BUSCAPRONTA GEN correspondente e o número de vezes em que encontrou o SOBRENOME PESQUISADO. Número eventualmente existente à direita do sobrenome (e na mesma linha) indica número de pessoas com aquele sobrenome cujas informações genealógicas são apresentadas. O valor de cada endereço Internet solicitado está em nosso site www.buscapronta.com . Para dados especificamente de registros gerais pesquise nos arquivos BUSCAPRONTA DIV. ATENÇÃO: Quando pesquisar em nossos arquivos, ao digitar o sobrenome procurado, faça- o, sempre que julgar necessário, COM E SEM os acentos agudo, grave, circunflexo, crase, til e trema. Sobrenomes com (ç) cedilha, digite também somente com (c) ou com dois esses (ss). Sobrenomes com dois esses (ss), digite com somente um esse (s) e com (ç). (ZZ) digite, também (Z) e vice-versa. (LL) digite, também (L) e vice-versa. Van Wolfgang – pesquise Wolfgang (faça o mesmo com outros complementos: Van der, De la etc) Sobrenomes compostos ( Mendes Caldeira) pesquise separadamente: MENDES e depois CALDEIRA. Tendo dificuldade com caracter Ø HAMMERSHØY – pesquise HAMMERSH HØJBJERG – pesquise JBJERG BUSCAPRONTA não reproduz dados genealógicos das pessoas, sendo necessário acessar os documentos Internet correspondentes para obter tais dados e informações. DESEJAMOS PLENO SUCESSO EM SUA PESQUISA.
    [Show full text]
  • 39400 13-11 Legala
    Government Gazette Staatskoerant REPUBLIC OF SOUTH AFRICA REPUBLIEK VAN SUID-AFRIKA November Vol. 605 Pretoria, 13 2015 November No. 39400 PART 1 OF 2 LEGAL NOTICES A WETLIKE KENNISGEWINGS ISSN 1682-5843 N.B. The Government Printing Works will 39400 not be held responsible for the quality of “Hard Copies” or “Electronic Files” submitted for publication purposes 9 771682 584003 AIDS HELPLINE: 0800-0123-22 Prevention is the cure 2 No. 39400 GOVERNMENT GAZETTE, 13 NOVEMBER 2015 WARNING!!! To all suppliers and potential suppliers of goods to the Government Printing Works The Government Printing Works would like to warn members of the public against an organised syndicate(s) scamming unsuspecting members of the public and claiming to act on behalf of the Government Printing Works. One of the ways in which the syndicate operates is by requesting quotations for various goods and services on a quotation form with the logo of the Government Printing Works. Once the official order is placed the syndicate requesting upfront payment before delivery will take place. Once the upfront payment is done the syndicate do not deliver the goods and service provider then expect payment from Government Printing Works. Government Printing Works condemns such illegal activities and encourages service providers to confirm the legitimacy of purchase orders with GPW SCM, prior to processing and delivery of goods. To confirm the legitimacy of purchase orders, please contact: Renny Chetty (012) 748-6375 ([email protected]), Anna-Marie du Toit (012) 748-6292 ([email protected]) and Siraj Rizvi (012) 748-6380 ([email protected]) This gazette is also available free online at www.gpwonline.co.za STAATSKOERANT, 13 NOVEMBER 2015 No.
    [Show full text]
  • Continuous Light on Tomato
    CONTINUOUS LIGHT ON TOMATO From Gene to Yield Aarón I. Vélez-Ramírez i Thesis committee Promotor Prof. Dr Harro J. Bouwmeester Professor of Plant Physiology Wageningen University Co-promotors Dr Wim van Ieperen Assistant professor, Horticulture and Product Physiology Wageningen University Dr Dick Vreugdenhil Associate professor, Laboratory of Plant Physiology Wageningen University Other members Prof. Dr Ton Bisseling, Wageningen University Prof. Dr Roberta Croce, VU University Amsterdam, The Netherlands Prof. Dr Gerrit T.S. Beemster, University of Antwerp, Belgium Dr. Ronald Pierik, Utrecht University, The Netherlands This research was conducted under the auspices of the Graduate School of Experimental Plant Sciences (EPS). ii CONTINUOUS LIGHT ON TOMATO From Gene to Yield Aarón I. Vélez-Ramírez Thesis submitted in fulfillment of the requirements for the degree of doctor at Wageningen University by the authority of the Rector Magnificus Prof. Dr M.J. Kropff, in the presence of the Thesis Committee appointed by the Academic Board to be defended in public on Friday 19 September 2014 at 11 a.m. in the Aula. iii Aarón I. Vélez Ramírez Continuous Light on Tomato. From Gene to Yield 214 pages PhD thesis, Wageningen University , Wageningen, NL (2014) With references, summaries in English and Dutch ISBN 978-94-6257-078-8 iv Contents Chapter 1 | 1 General Introduction. Continuous-light-induced injury in tomato: An old enigma 13 Chapter 2 | Plants under continuous light Chapter 3 | 29 Continuous light as a way to increase greenhouse tomato production:
    [Show full text]
  • Start Number Name Surname Team City, Country Time 11001 Tommy
    Start number Name Surname Team City, Country Time 11001 Tommy Frølund Jensen Kongens lyngby, Denmark 89:20:46 11002 Emil Boström Lag Nord Linköping, Sweden 98:19:04 11003 Lovisa Johansson Lag Nord Burträsk, Sweden 98:19:02 11005 Maurice Lagershausen Huddinge, Sweden 102:01:54 11011 Hyun jun Lee Korea, (south) republic of 122:40:49 11012 Viggo Fält Team Fält Linköping, Sweden 57:45:24 11013 Richard Fält Team Fält Linköping, Sweden 57:45:28 11014 Rasmus Nummela Rackmannarna Pjelax, Finland 98:59:06 11015 Rafael Nummela Rackmannarna Pjelax, Finland 98:59:06 11017 Marie Zølner Hillerød, Denmark 82:11:49 11018 Niklas Åkesson Mellbystrand, Sweden 99:45:22 11019 Viggo Åkesson Mellbystrand, Sweden 99:45:22 11020 Damian Sulik #StopComplaining Siegen, Germany 101:13:24 11023 Bruno Svendsen Tylstrup, Denmark 74:48:08 11024 Philip Oswald Lakeland, USA 55:52:02 11025 Virginia Marshall Lakefield, Canada 55:57:54 11026 Andreas Mathiasson Backyard Heroes Ödsmål, Sweden 75:12:02 11028 Stine Andersen Brædstrup, Denmark 104:35:37 11030 Patte Johansson Tiger Södertälje, Sweden 80:24:51 11031 Frederic Wiesenbach BB Dahn, Germany 101:21:50 11032 Romea Brugger BB Berlin, Germany 101:22:44 11034 Oliver Freudenberg Heyda, Germany 75:07:48 11035 Jan Hennig Farum, Denmark 82:11:50 11036 Robert Falkenberg Farum, Denmark 82:11:51 11037 Edo Boorsma Sint annaparochie, Netherlands 123:17:34 11038 Trijneke Stuit Sint annaparochie, Netherlands 123:17:35 11040 Sebastian Keck TATSE Gieäen, Germany 104:08:01 11041 Tatjana Kage TATSE Gieäen, Germany 104:08:02 11042 Eun Lee
    [Show full text]
  • 2022 NC National Qualifiers with Events As Of
    North Carolina Senior Games Qualifiers for 2022 National Senior Games presented by Humana as of 12/31/2020 GFL LAST NAME FIRST NAME QUAL INTO ABBOTT DEKE Pickleball - Mens Doubles ABEL NORA Basketball - Womens ABERNATHY MIKE Softball - Mens ABSHER JUDY Table Tennis - Womens Doubles ABSHER JUDY Track & Field - Womens - 100M ABSHER JUDY Track & Field - Womens - 50M ACKERMAN LOUISE Road Race - Womens - 10K ACKERMAN LOUISE Road Race - Womens - 5K ADAMS DIANE Softball - Womens ADAMS JERRY Road Race - Mens - 10K ADAMS JERRY Road Race - Mens - 5K ADAMS JERRY Track & Field - Mens - 1,500M ADKINS WINDELL Bowling Preliminaries - Mens Doubles ADKINS WINDELL Bowling Preliminaries - Mens Singles AGARD BASIL Table Tennis - Mens Doubles AGNER MARY JO Swimming - Womens - 100Y Fly AGNER MARY JO Swimming - Womens - 100Y Free AGNER MARY JO Swimming - Womens - 100Y IM AGNER MARY JO Swimming - Womens - 200Y Fly AGNER MARY JO Swimming - Womens - 200Y Free AGNER MARY JO Swimming - Womens - 200Y IM AGNER MARY JO Swimming - Womens - 400Y IM AGNER MARY JO Swimming - Womens - 500Y Free AGNER MARY JO Swimming - Womens - 50Y Fly AGNER MARY JO Swimming - Womens - 50Y Free AGURS BENJAMIN Basketball - Mens AIKENS MIRIAM Bowling Preliminaries - Mixed Doubles AIKENS MIRIAM Bowling Preliminaries - Womens Singles AIKENS NORRIS Bowling Preliminaries - Mixed Doubles ALBRITTON BOB Road Race - Mens - 10K ALDRIDGE CHARLES Softball - Mens ALEXANDER DAVID Track & Field - Mens - Long Jump ALLEN DAVID Swimming - Mens - 100Y IM ALLEN DAVID Swimming - Mens - 50Y Back ALLEN DAVID Swimming - Mens - 50Y Free ALLEN GEORGE Softball - Mens ALLEN JOHN Basketball - Mens ALLEN JOHN Basketball - Mens ALLEN JOHN Softball - Mens ALLEN KIMBERLY Archery - Womens - Barebow Compound ALLEN KIMBERLY Archery - Womens - Barebow Recurve ALLEN MARK Tennis - Mixed Doubles Regardless of an athlete's age at the time of qualification, age division for the 2022 National Senior Games will be determined by the athlete’s age as of DECEMBER 31, 2022.
    [Show full text]
  • Zachary Steel
    MENTAL DISORDER AMONGST PEOPLE OF VIETNAMESE BACKGROUND: PREVALENCE, TRAUMA AND CULTURE Zachary Steel A thesis submitted in fulfilment of the requirements for the degree of Doctor of Philosophy School of Psychiatry Faculty of Medicine, University of New South Wales Sydney Australia June 2008 ii Abstract The role that culture and trauma plays in shaping mental health outcomes continues to dominate debate in the field of transcultural and post-conflict mental health. The broad aim of this thesis is to investigate key issues relevant to these two factors in relation to the Vietnamese. A meta-analysis of international epidemiological research indicated that countries of North and South East Asia appear to manifest low rates of mental disorder compared to English-speaking countries. A meta-regression analysis of research undertaken specifically with refugee and conflict-affected populations, confirmed a robust association between torture and general trauma and risk to mental disorder. The thesis then examines data from three population-based mental health surveys: 1,161 Vietnamese-Australian residents in the state of New South Wales; 3,039 Vietnamese resident in the Mekong Delta region of Vietnam; and 7,961 Australian-born persons drawn from a national survey. All surveys applied the Composite International Diagnostic Interview, with the Vietnamese surveys also applying the Phan Vietnamese Psychiatric Rating Scale, an indigenously-derived measure of mental disorder. The ICD-10 classification system yielded lowest rates amongst Vietnamese in the Mekong Delta, intermediate amongst Vietnamese in NSW; and highest rates amongst the Australian-born population. The Phan Vietnamese Psychiatric Rating Scale added a substantial number of cases in both Vietnamese samples.
    [Show full text]
  • Nummer 26/10 18 Augustus 2010 Nummer 26/10 1 18 Augustus 2010
    Nummer 26/10 18 augustus 2010 Nummer 26/10 1 18 augustus 2010 Inleiding Introduction Hoofdblad Patent Bulletin Het Blad de Industriële Eigendom verschijnt op de The Patent Bulletin appears on the 3rd working derde werkdag van een week. Indien NL day of each week. If the Netherlands Patent Octrooicentrum op deze dag is gesloten, wordt de Office is closed to the public on the above verschijningsdag van het blad verschoven naar de mentioned day, the date of issue of the Bulletin is eerstvolgende werkdag, waarop Octrooicentrum the first working day thereafter, on which the Nederland is geopend. Het blad verschijnt alleen in Office is open. Each issue of the Bulletin consists electronische vorm. Elk nummer van het blad bestaat of 14 headings. uit 14 rubrieken. Bijblad Official Journal Verschijnt vier keer per jaar (januari, april, juli, Appears four times a year (January, April, July, oktober) in electronische vorm via de website van NL October) in electronic form on the website of the Octrooicentrum. Het Bijblad bevat officiële Netherlands Patent Office. The Official Journal mededelingen en andere wetenswaardigheden contains announcements and other things worth waarmee NL Octrooicentrum en zijn klanten te maken knowing for the benefit of the Netherlands Patent hebben. Office and its customers. Abonnementsprijzen per (kalender)jaar: Subscription rates per calendar year: Hoofdblad en Bijblad: verschijnt gratis in Patent Bulletin and Official Journal: free of electronische vorm op de website van NL charge in electronic form on the website of
    [Show full text]
  • Government Gazette Staatskoerant REPUBLIC of SOUTH AFRICA REPUBLIEK VAN SUID-AFRIKA
    Government Gazette Staatskoerant REPUBLIC OF SOUTH AFRICA REPUBLIEK VAN SUID-AFRIKA September Vol. 627 Pretoria, 8 2017 September No. 41098 PART 1 OF 2 LEGAL NOTICES A WETLIKE KENNISGEWINGS ISSN 1682-5843 N.B. The Government Printing Works will 41098 not be held responsible for the quality of “Hard Copies” or “Electronic Files” submitted for publication purposes 9 771682 584003 AIDS HELPLINE: 0800-0123-22 Prevention is the cure 2 No. 41098 GOVERNMENT GAZETTE, 8 SEPTEMBER 2017 IMPORTANT NOTICE: THE GOVERNMENT PRINTING WORKS WILL NOT BE HELD RESPONSIBLE FOR ANY ERRORS THAT MIGHT OCCUR DUE TO THE SUBMISSION OF INCOMPLETE / INCORRECT / ILLEGIBLE COPY. NO FUTURE QUERIES WILL BE HANDLED IN CONNECTION WITH THE ABOVE. Table of Contents LEGAL NOTICES BUSINESS NOTICES • BESIGHEIDSKENNISGEWINGS Gauteng ....................................................................................................................................... 13 Eastern Cape / Oos-Kaap ................................................................................................................. 14 Free State / Vrystaat ........................................................................................................................ 15 KwaZulu-Natal ................................................................................................................................ 15 Mpumalanga .................................................................................................................................. 16 Western Cape / Wes-Kaap ...............................................................................................................
    [Show full text]
  • Surname Name No Date 20S 30S 40S 50S 60S 70S 80S 90S 00S 10S 2Ink
    Surname Name No Date 20s 30s 40s 50s 60s 70s 80s 90s 00s 10s 2Ink [public artist] Olckers (2013) Abbott Graham Altschuler (2008) Altschuler (2008) Abbott Sara Campbell (1997) Abels Fabian Grunebaum & Grunebaum & (2012) (2012) Abraham Vuyani The Brett Kebble Art Awards (2004) ABRAMS Lionel (b. 1931; d.) Alexander (1974), Van Zyl (2008) Martienssen (1966), Berman (1975), Alexander & (1990), Scholtz (2007), Law- Fransen (1982), Berman (1983), Scholtz (2007) Scholtz (2007) Viljoen (2008a) Van Zyl (2008) Yntema (1970), Berman (1975) Acocks John (b. 1911; d. 1979) Coetzee & (2014) Weinberg (2015) Coetzee & (2014) Coetzee & (2014) Acton Jeremy Grunebaum & (2012) Adams Albert (b.1930) Alexander (1974), Willemse (2000) Siebrits (2003d), Van Robbroeck Pissarra (2011) Grosvenor (1995) FNB Joburg Art Fair Law-Viljoen (2008a) Stevenson (2005b), (2011) (2010), Subiros (2007), Carman (2010), Van Robbroeck (2011) Adams Fuad Essers & (2016) Adams Hassiem Maurice (1995) Adams Igshaan FNB Joburg Art Fair (2015), Adams John Stretton (2012) Adams Shelley (b.1952) Campbell (1997) Adams Tamsyn Grundlingh (2005) Adamson Val Gutberlet & (2012) Danby & (1995), Brown (2004) Brown (2004) Aeby-Zini Doris Cape Town Triennial (1991) Afrapix [collective] The Poster Book Collective (1991), Miescher & (2004), Seidman (2007), Africa Courtney Weinberg (2015) African Institute of Art [collective] Till (1995) (Funda Art Centre) Aggenbach Sanell (b. 1975) Edmunds (2002), The Borman (2011), Brett Kebble Art FNB Joburg Art Fair Awards (2003), (2011), FNB Joburg Lamprecht (2003), Art Fair (2013), Grundlingh (2005), Pather (2007), Gruber & (2007), FNB Joburg Art Fair (2008), FNB Joburg Art Fair (2009), FNB Joburg Art Fair (2010), Borman (2012) AI [collective] Olckers (2013) Aikman Jake FNB Joburg Art Fair FNB Joburg Art Fair (2008), FNB Joburg Art (2011), FNB Joburg Fair (2009), SMAC Art Fair (2013), (2009), FNB Joburg Art Fair (2010), AINSLIE Bill (b.
    [Show full text]
  • ANNUAL REPORT 2018 Institute of Ion Beam Physics and Materials Research
    ANNUAL REPORT 2018 Institute of Ion Beam Physics and Materials Research HZDR-097 Wissenschaftlich-Technische Berichte HZDR–097 Annual Report 2018 Institute of Ion Beam Physics and Materials Research Editors J. Fassbender, M. Helm, P. Zahn Cover Picture The cover picture illustrates an artistic arrangement of two-dimensional compositional maps (hexagons) from GaAs / InAlAs / InGaAs core / shell / shell nanowire cross-sections. The different colors correspond to different group-III elements (blue for gallium, red for indium, and cyan for aluminum) as measured by energy-dispersive X-ray spectroscopy in scanning transmission electron microscopy mode. The pattern of hexagons is a repetitive reproduction of three different compositional maps. The large lattice-mismatch between the thin core (approximately 25 nm in diameter) and the shells causes the development of tensile hydrostatic strain up to 7 % in the core. In that way, we can tune the bandgap of the GaAs core in a very wide range, rendering these nanowires suitable for photonic devices across the near-infrared range, including telecom photonics at 1.3 and 1.55 μm. The fact that the nanowires grow epitaxially on Si substrates could enable in the future the monolithic integration of GaAs-based devices in Si-CMOS circuits. Two dark-field optical microscopy images of randomly dispersed nanowires (removed from their substrate) are also illustrated. The nanowire length is approximately 2 μm. Image: © HZDR / L. Balaghi, R. Hübner, E. Dimakis For further information see: Balaghi, L. et al., Widely tunable GaAs bandgap via strain engineering in core/shell nanowires with large lattice mismatch, Nature Communications 10, 2793 (2019) Many thanks for providing material and for technical assistance to: S.
    [Show full text]
  • 165 the Meeting Was Called to Order by Board Secretary Mr. Michael C
    Minutes of the Organization Meeting of the Monroe Township Board of Education held on May 11, 2011 at the Monroe Township High School. 165 The meeting was called to order by Board Secretary Mr. Michael C. Gorski at 7:00 p.m. ATTENDANCE BOARD MEMBERS PRESENT Ms. Amy Antelis Mr. Marvin I. Braverman Mr. Ken Chiarella Mr. Lew Kaufman Mr. Mark Klein Ms. Kathy Kolupanowich Mr. John Leary Mr. Louis C. Masters Mr. Ira Tessler BOARD MEMBER ABSENT None JAMESBURG BOARD MEMBER REPRESENTATIVE PRESENT Ms. Patrice Faraone STUDENT BOARD MEMBERS PRESENT None STUDENT BOARD MEMBERS ABSENT Ms. Reena Dholakia Mr. Jonathan Kim STAFF Dr. Kenneth R. Hamilton, Superintendent of Schools Mr. Michael C. Gorski, Business Administrator/Board Secretary Mr. Jeff Gorman, Assistant Superintendent of Schools MEMBERS OF THE PUBLIC/STAFF – 94 Minutes of the Organization Meeting of the Monroe Township Board of Education held on May 11, 2011 at the Monroe Township High School. 166 After the Pledge of Allegiance and roll call, the Board Secretary read the following statement: In accordance with the provisions of the New Jersey Open Public Meetings Law, the Monroe Township Board of Education has caused notice of this meeting to be published by having the date, time and place thereof posted May 6, 2011: 1. At all Schools, 2. Home News Tribune, 3. Cranbury Press, and 4. Filed with the Clerk of the Municipality. ELECTION RESULTS 1. Mr. Gorski announced that the candidates that won a position on the Board of Education were Ms. Amy Antelis, Mr. Ken Chiarella, and Ms. Kathy Kolupanowich A computer printout of the 2011/12 Annual School Election results is attached to the official set of minutes.
    [Show full text]
  • 2402 a MOMOLI Fausto 9601 AABO Tom Erik 14405 AAL Stephen 9602
    2402 A MOMOLI Fausto 9601 AABO Tom Erik 14405 AAL Stephen 9602 AALBERS Marcel 9603 AALDERINK Bernard 2403 AALST Bas 9604 AALST Janno 17400 AALST VAN Jos 9605 AANDEWIEL Dave 9606 AARON Gibney 2404 AARON Saturley 9607 AARON PIPER Aaron 9608 AARTS Bart 13847 AARTS Frank 9609 AARTS Noël 9610 AARTS Stefan 9612 AARTSEN Gerben 9611 AARTSEN Bas 5001 AASER Knut 5002 AASLUND Stein 9613 ABEELE Michael 5003 ABELOOS Dirk 2405 ABEN Wilfried 15001 ABEN Rudi 9614 ABLITT Nicholas 9615 ABMA Margje 9616 ABMA Piet 9617 ABMA Roy 9444 ABRAHAM Jo 1 ACHLEITNER Florian 9305 ACHTEN Robin 9618 ACHTERBERG Hans 15002 ACHTERGAELE Maxim 2 ACHTERGAELE Ruben 5004 ACKAERT Luc 5005 ACKE Stefaan 17401 ACKLAM David 13860 ACKX Sylvain 5006 ACOE Marc 5008 ADAM Nathalie 5007 ADAM Jeroen 15003 ADAM Jo 9620 ADAM Morris 9621 ADAM Witherington 9619 ADAM Cadle 9622 ADAM Werney 2206 ADAMS Danny 17016 ADAMS Lieven 9623 ADAMS Laura 5009 ADÁN Pinto 17402 ADELAARS Patrick 9624 ADEMA Bert 9625 ADITYA BHASKAR Aditya 14388 ADLINGTON Nick 9626 ADRIAANSEN Arjan 9627 ADRIAANSEN Teun 5010 ADRIAENS Tim 3 ADRIAENSEN Bart 17007 ADRIAENSEN Philippe 9628 ADRIAENSEN Theo 4 ADRIAENSENS Guy 9451 ADRIAENSSENS Sven 17041 ADRIAENSSENS Yannick 9629 ADRIAN O Neill 9630 ADRIAN WALSH Adrian 9398 ADYNS Leslie 9631 AECKERLIN Ree 5011 AELBRECHT Luc 5012 AELBRECHT Stefaan 5 AELBRECHT Geert 18123 AELBRECHT Kris 6 AELBRECHT Hans 7 AELTERMAN Peter 5013 AELTERMAN Wim 5014 AELVOET Matthias 5015 AERDEN Luc 13949 AERNOUTS Paul 17017 AERTGEERTS Bjorn 17087 AERTS Karl 17096 AERTS Ben 16703 AERTS Luc 8805 AERTS Ivan 15007
    [Show full text]