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  • The Proceedings of the Conference on the Challenges of Contemporary Cell Biology Molecular Genetics, System Biology, Bioinformatics
    University of Lodz The Proceedings of the Conference on The Challenges of Contemporary Cell Biology Molecular Genetics, System Biology, Bioinformatics April 20 – 21, 2009 The Conference to Honor Professor Maria J. Olszewska on Her Jubilee Łódź University Press, 2009 Conference on The Challenges of Contemporary Cell Biology – April 20-21, 2009 Sponsors of the Conference 2 Conference on The Challenges of Contemporary Cell Biology – April 20-21, 2009 Patronage: Rector of the University of Lodz – Professor Włodzimierz Nykiel, Ph.D. Conference supported by Polish Ministry of Science and Higher Education Conference Organizers: The Committee on Cell Biology of Polish Academy of Sciences Institute of Physiology, Cytology, and Cytogenetics, University of Lodz The Lodz Branch of the Polish Academy of Sciences Organizing Committee: Chairman: Andrzej K. Kononowicz – University of Lodz Vice-Chairman: Elżbieta Wyroba – The Committee on Cell Biology of Polish Academy of Sciences Members: Maria Kwiatkowska – University of Lodz Jerzy Kawiak – Editor of Advances in Cell Biology (Postępy Biologii Komórki) Barbara Gabara – University of Lodz Mirosław Godlewski – University of Lodz Jacek Jurczakowski – The Lodz Branch of the Polish Academy of Sciences Kazimierz Marciniak – University of Lodz Janusz Maszewski – University of Lodz Maria Skłodowska – University of Lodz Scientific Committee: Maria Kwiatkowska – University of Lodz Jerzy Kawiak – Editor of Advances in Cell Biology (Postępy Biologii Komórki) Andrzej K. Kononowicz – University of Lodz Janusz Maszewski – University of Lodz Conference Office: Ewa Mikołajczyk-Zając – University of Lodz Violetta Macioszek – University of Lodz Katarzyna Hnatuszko-Konka – University of Lodz (Book cover and Conference website design) Tomasz Kowalczyk – University of Lodz Department of Genetics and Plant Molecular Biology and Biotechnology Faculty of Biology and Environmental Protection University of Lodz S.
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  • Guava (Psidium Guajava L.) Leaves: Nutritional Composition, Phytochemical Profile, and Health-Promoting Bioactivities
    foods Review Guava (Psidium guajava L.) Leaves: Nutritional Composition, Phytochemical Profile, and Health-Promoting Bioactivities Manoj Kumar 1 , Maharishi Tomar 2, Ryszard Amarowicz 3,* , Vivek Saurabh 4 , M. Sneha Nair 5, Chirag Maheshwari 6, Minnu Sasi 7, Uma Prajapati 4, Muzaffar Hasan 8, Surinder Singh 9, Sushil Changan 10 , Rakesh Kumar Prajapat 11, Mukesh K. Berwal 12 and Varsha Satankar 13 1 Chemical and Biochemical Processing Division, ICAR—Central Institute for Research on Cotton Technology, Mumbai 400019, India; [email protected] 2 ICAR—Indian Grassland and Fodder Research Institute, Jhansi 284003, India; [email protected] 3 Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Tuwima 10 Str., 10-748 Olsztyn, Poland 4 Division of Food Science and Postharvest Technology, ICAR—Indian Agricultural Research Institute, New Delhi 110012, India; [email protected] (V.S.); [email protected] (U.P.) 5 Department of Nutrition and Dietetics, Faculty of Allied Health Sciences, Manav Rachna International Institute of Research and Studies, Faridabad 121004, Haryana, India; [email protected] 6 Department of Agriculture Energy and Power, ICAR—Central Institute of Agricultural Engineering, Bhopal 462038, India; [email protected] 7 Division of Biochemistry, ICAR—Indian Agricultural Research Institute, New Delhi 110012, India; [email protected] 8 Agro Produce Processing Division, ICAR—Central Institute of Agricultural Engineering, Citation: Kumar, M.; Tomar, M.; Bhopal 462038, India; [email protected] 9 Amarowicz, R.; Saurabh, V.; Nair, Dr. S.S. Bhatnagar University Institute of Chemical Engineering and Technology, Panjab University, Chandigarh 160014, India; [email protected] M.S.; Maheshwari, C.; Sasi, M.; 10 Division of Crop Physiology, Biochemistry and Post-Harvest Technology, ICAR—Central Potato Research Prajapati, U.; Hasan, M.; Singh, S.; Institute, Shimla 171001, India; [email protected] et al.
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  • Phytopharmacological Overview of Psidium Guajava Linn
    Pharmacogn. J. Review Article A multifaceted peer reviewed journal in the field of Pharmacognosy and Natural Products www.phcogfirst.com/phcogj Phytopharmacological overview of Psidium guajava Linn. Vijaya Anand1, Manikandan2, Vijaya Kumar2, Sampath Kumar3, Pushpa4, Agaath Hedina1 1Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore–641 046, Tamil Nadu, INDIA. 2Department of Biochemistry, M.I.E.T. Arts and Science College, Tiruchirappalli–620 007, Tamil Nadu, INDIA. 3Department of Chemistry and Biosciences, SASTRA University, Kumbakonam–612 001, Tamil Nadu, INDIA. 4Department of Microbiology, Cauvery College for Women, Tiruchirappalli–620 018, Tamil Nadu, INDIA. ABSTRACT Psidium guajava Linn. possesses useful medicinal benefits. It has been recognized as the medicinally essential phytoconstituents, such as pheno- Corresponding author: lic, flavonoid and carotenoid. Numerous pharmacological investigation have Dr. A. Vijaya Anand, confirmed that the ability of this plant is to exhibit antimicrobial, antidia- Associate Professor and Head, Department of Human Genetics and betic, cardioprotective, neuroprotective, hepatoprotective, antioxidant and Molecular Biology, Bharathiar University, Coimbatore–641 046, anticancer activities and it supports the traditional uses. This is a compre- Tamil Nadu, INDIA. hensive of the phytoconstituents and pharmacological benefits. Mobile: +91 9842525830 Key words: Psidium guajava, Antimicrobial, Antidiabetic, Antioxidant, Hep- E-mail: [email protected] atoprotective, Anticancer. DOI: 10.5530/pj.2016.4.3 INTRODUCTION (9Z)-, (13Z)-, and (15Z)-lycopene, (all-E,3R)-beta-cryptoxanthin, (all- E, 3R)-rubixanthin, (all-E,3S,5R,8S)-cryptoflavin, (all-E,3R,3’R, 6’R)- Psidium guajava Linn. is commonly called guave, goyave in French; lutein, (all-E,3S,5R,6R,3’S,5’R,8’R)-, and (all-E,3S,5R,6R,3’S, 5’R,8’S)- guave, guavenbaum, in German; banjiro in Japanese; goiaba, in Portu- neochrome.9 Guavanoic acid, guavacoumaric acid, 2α-hydroxyursolic 1 gal; arac¸ guaiaba in Brazil; and guava in English.
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  • Karanja” Belonging to Family Leguminosae
    Int. J. Pharm. Sci. Rev. Res., 59(1), November - December 2019; Article No. 05, Pages: 22-29 ISSN 0976 – 044X Review Article The Review: Phytochemical and Bioactive Screening of “Karanja” belonging to family Leguminosae. Preethima G1*, Ananda V 1, D. Visagaperumal 1, Vineeth Chandy 1, Prashanthi P 2 1Department of Pharmaceutical chemistry, T. John College of Pharmacy, Bangalore, India. 2Department of Pharmacognosy, T. John College of Pharmacy, Bangalore, Karnataka, India. *Corresponding author’s E-mail: [email protected] Received: 10-09-2019; Revised: 22-10-2019; Accepted: 03-11-2019. ABSTRACT Traditional medicine consists of huge number of plants with different pharmacological and medicinal values. The bioactive molecules have been identified. Pongamia pinnata (Linn.) Pierre is one of the oldest plants with numerous properties, which is found all over the globe. It is commonly known as “Indian beech tree” and has been identified in Ayurvedic and Siddha system of medicines for the healing effect of human beings. Different parts of whole plant are used for treatment of various diseases including rheumatism, diarrhoea, gonorrhoea, whooping cough, leprosy and bronchitis. Extracts of the whole plant show significant anti- plasmodial, anti-ulcerogenic, anti-diarrhoeal, anti-inflammatory, anti-fungal, and analgesic activities. Its oil is used as a source of biodiesel. The present review paper was aimed to u0pdate the information of Pongamia pinnata with reference to its pharmacological properties, chemical constituents and its use as anti-urolithiatic agent for the treatment of Urolithiasis. Keywords: Pongamia pinata, Indian beech tree, Healing effect, Anti-urolithiatic agent, urolithiasis. INTRODUCTION four- to five-toothed, with a papilionaceous corolla.
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  • The Phytochemistry of Cherokee Aromatic Medicinal Plants
    medicines Review The Phytochemistry of Cherokee Aromatic Medicinal Plants William N. Setzer 1,2 1 Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA; [email protected]; Tel.: +1-256-824-6519 2 Aromatic Plant Research Center, 230 N 1200 E, Suite 102, Lehi, UT 84043, USA Received: 25 October 2018; Accepted: 8 November 2018; Published: 12 November 2018 Abstract: Background: Native Americans have had a rich ethnobotanical heritage for treating diseases, ailments, and injuries. Cherokee traditional medicine has provided numerous aromatic and medicinal plants that not only were used by the Cherokee people, but were also adopted for use by European settlers in North America. Methods: The aim of this review was to examine the Cherokee ethnobotanical literature and the published phytochemical investigations on Cherokee medicinal plants and to correlate phytochemical constituents with traditional uses and biological activities. Results: Several Cherokee medicinal plants are still in use today as herbal medicines, including, for example, yarrow (Achillea millefolium), black cohosh (Cimicifuga racemosa), American ginseng (Panax quinquefolius), and blue skullcap (Scutellaria lateriflora). This review presents a summary of the traditional uses, phytochemical constituents, and biological activities of Cherokee aromatic and medicinal plants. Conclusions: The list is not complete, however, as there is still much work needed in phytochemical investigation and pharmacological evaluation of many traditional herbal medicines. Keywords: Cherokee; Native American; traditional herbal medicine; chemical constituents; pharmacology 1. Introduction Natural products have been an important source of medicinal agents throughout history and modern medicine continues to rely on traditional knowledge for treatment of human maladies [1]. Traditional medicines such as Traditional Chinese Medicine [2], Ayurvedic [3], and medicinal plants from Latin America [4] have proven to be rich resources of biologically active compounds and potential new drugs.
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  • Phytochem Referenzsubstanzen
    High pure reference substances Phytochem Hochreine Standardsubstanzen for research and quality für Forschung und management Referenzsubstanzen Qualitätssicherung Nummer Name Synonym CAS FW Formel Literatur 01.286. ABIETIC ACID Sylvic acid [514-10-3] 302.46 C20H30O2 01.030. L-ABRINE N-a-Methyl-L-tryptophan [526-31-8] 218.26 C12H14N2O2 Merck Index 11,5 01.031. (+)-ABSCISIC ACID [21293-29-8] 264.33 C15H20O4 Merck Index 11,6 01.032. (+/-)-ABSCISIC ACID ABA; Dormin [14375-45-2] 264.33 C15H20O4 Merck Index 11,6 01.002. ABSINTHIN Absinthiin, Absynthin [1362-42-1] 496,64 C30H40O6 Merck Index 12,8 01.033. ACACETIN 5,7-Dihydroxy-4'-methoxyflavone; Linarigenin [480-44-4] 284.28 C16H12O5 Merck Index 11,9 01.287. ACACETIN Apigenin-4´methylester [480-44-4] 284.28 C16H12O5 01.034. ACACETIN-7-NEOHESPERIDOSIDE Fortunellin [20633-93-6] 610.60 C28H32O14 01.035. ACACETIN-7-RUTINOSIDE Linarin [480-36-4] 592.57 C28H32O14 Merck Index 11,5376 01.036. 2-ACETAMIDO-2-DEOXY-1,3,4,6-TETRA-O- a-D-Glucosamine pentaacetate 389.37 C16H23NO10 ACETYL-a-D-GLUCOPYRANOSE 01.037. 2-ACETAMIDO-2-DEOXY-1,3,4,6-TETRA-O- b-D-Glucosamine pentaacetate [7772-79-4] 389.37 C16H23NO10 ACETYL-b-D-GLUCOPYRANOSE> 01.038. 2-ACETAMIDO-2-DEOXY-3,4,6-TRI-O-ACETYL- Acetochloro-a-D-glucosamine [3068-34-6] 365.77 C14H20ClNO8 a-D-GLUCOPYRANOSYLCHLORIDE - 1 - High pure reference substances Phytochem Hochreine Standardsubstanzen for research and quality für Forschung und management Referenzsubstanzen Qualitätssicherung Nummer Name Synonym CAS FW Formel Literatur 01.039.
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  • The Pongam Tree, Unfit for Florida Landscaping, Has Multiple Practical Uses in Under-Developed Lands
    Proc. Fla. State Hort. Soc. 103:338-343. 1990. THE PONGAM TREE, UNFIT FOR FLORIDA LANDSCAPING, HAS MULTIPLE PRACTICAL USES IN UNDER-DEVELOPED LANDS Julia F. Morton come 6 to 14 in long; have 3 to 9 opposite, elliptic or obo- Morton Collectanea vate leaflets, 2 to 6 in long, pointed at the apex, dark- University of Miami green, glossy on the upper surface, paler, dull, with prom Coral Gables, FL 33124 inent veins on the underside. The strongly fragrant, pea- like flowers, V2 in long, may be white, pale-pink, or laven Additional index words. Pongamia pinnata, P. glabra, Derris der with purple calyx; are borne in axillary racemes to 10 indica. in long. The short-stalked pods, borne in great abundance 3 to 4 months after blooming, are somewhat almond- Abstract. The pong am tree, Pongamia pinnata (Linn.) Merr. (P. shaped, with a short, recurved beak at the apex. They are glabra Vent, nom Meg.) (7), grows wild on seashores and about lA in thick, II/2 to 2V2 in long, V4 to 1 V2 in wide; along inland waterways from India and Malaysia to northern bright-green and waxy when immature; light-brown when Australia, the Philippines and Polynesia. It was introduced mature and dry; leathery and durable; remain on the tree into Hawaii by Hillebrand in the 1860#s. The U.S. Department all year, are difficult to crush on the ground, creating a of Agriculture received seeds from Sri Lanka in 1910, from long-lasting litter. In the words of Cowen (26): "The Mauritius in 1911, from India in 1912, from Egypt in 1916, ground below is always covered with a crackling carpet." and from India in 1926.
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  • UHPLC-MS Chemical Fingerprinting and Antioxidant, Antiproliferative, and Enzyme Inhibition Potential of Gaultheria Pumila Berries
    H OH metabolites OH Article UHPLC-MS Chemical Fingerprinting and Antioxidant, Antiproliferative, and Enzyme Inhibition Potential of Gaultheria pumila Berries Carlos Fernández-Galleguillos 1, Luisa Quesada-Romero 2,*, Adrián Puerta 3, José M. Padrón 3 , Ernane Souza 4, Javier Romero-Parra 5 and Mario J. Simirgiotis 1,6,* 1 Instituto de Farmacia, Facultad de Ciencias, Universidad Austral de Chile, Campus Isla Teja, Valdivia 5090000, Chile; [email protected] 2 Facultad de Ciencias Para el Cuidado de la Salud, Universidad San Sebastián, Valdivia 5090000, Chile 3 BioLab, Instituto Universitario de Bio-Orgánica Antonio González (IUBO-AG), Universidad de La Laguna, 38206 La Laguna, Spain; [email protected] (A.P.); [email protected] (J.M.P.) 4 The Lloyd L. Gregory School of Pharmacy, Palm Beach Atlantic University, West Palm Beach, FL 33401, USA; [email protected] 5 Departamento de Química Orgánica y Fisicoquímica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Olivos 1007, Casilla 233, Santiago 6640022, Chile; [email protected] 6 Center for Interdisciplinary Studies on the Nervous System (CISNe), Universidad Austral de Chile, Valdivia 5090000, Chile * Correspondence: [email protected] (L.Q.-R.); [email protected] (M.J.S.); Tel.: +56-632632811 (L.Q.-R.) Citation: Fernández-Galleguillos, C.; Quesada-Romero, L.; Puerta, A.; Abstract: Gaultheria pumila (Ericaceae) (known as Chaura or Mutilla) is a Chilean native small Padrón, J.M.; Souza, E.; shrub that produces berry fruits consumed by local Mapuche people. In this study, the chemical Romero-Parra, J.; Simirgiotis, M.J. fingerprinting and antioxidant, enzyme inhibition, and antiproliferative activities of the berries UHPLC-MS Chemical Fingerprinting were investigated for the first time.
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  • Medicinal Uses, Phytochemistry and Pharmacology of Pongamia Pinnata (L.) Pierre: a Review
    Journal of Ethnopharmacology 150 (2013) 395–420 Contents lists available at ScienceDirect Journal of Ethnopharmacology journal homepage: www.elsevier.com/locate/jep Review Medicinal uses, phytochemistry and pharmacology of Pongamia pinnata (L.) Pierre: A review L.M.R. Al Muqarrabun a, N. Ahmat a,n, S.A.S. Ruzaina a, N.H. Ismail a, I. Sahidin b a Faculty of Applied Sciences, Universiti Teknologi MARA (UiTM), 40450 Shah Alam, Selangor, Malaysia b Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Haluoleo University (Unhalu), 93232 Kendari, Southeast Sulawesi, Indonesia article info abstract Article history: Ethnopharmacological relevance: Pongamia pinnata (L.) Pierre is one of the many plants with diverse Received 10 April 2013 medicinal properties where all its parts have been used as traditional medicine in the treatment and Received in revised form prevention of several kinds of ailments in many countries such as for treatment of piles, skin diseases, 19 August 2013 and wounds. Accepted 20 August 2013 Aim of this review: This review discusses the current knowledge of traditional uses, phytochemistry, Available online 7 September 2013 biological activities, and toxicity of this species in order to reveal its therapeutic and gaps requiring Keywords: future research opportunities. Pongamia pinnata Material and methods: This review is based on literature study on scientific journals and books from Fabaceae library and electronic sources such as ScienceDirect, PubMed, ACS, etc. Anti-diabetic Results: Several different classes of flavonoid derivatives, such as flavones, flavans, and chalcones, and Anti-inflammatory Karanjin several types of compounds including terpenes, steroid, and fatty acids have been isolated from all parts Pongamol of this plant.
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  • Analysis of the Binding and Interaction Patterns of 100 Flavonoids with the Pneumococcal Virulent Protein Pneumolysin: an in Silico Virtual Screening Approach
    Available online a t www.scholarsresearchlibrary.com Scholars Research Library Der Pharmacia Lettre, 2016, 8 (16):40-51 (http://scholarsresearchlibrary.com/archive.html) ISSN 0975-5071 USA CODEN: DPLEB4 Analysis of the binding and interaction patterns of 100 flavonoids with the Pneumococcal virulent protein pneumolysin: An in silico virtual screening approach Udhaya Lavinya B., Manisha P., Sangeetha N., Premkumar N., Asha Devi S., Gunaseelan D. and Sabina E. P.* 1School of Biosciences and Technology, VIT University, Vellore - 632014, Tamilnadu, India 2Department of Computer Science, College of Computer Science & Information Systems, JAZAN University, JAZAN-82822-6694, Kingdom of Saudi Arabia. _____________________________________________________________________________________________ ABSTRACT Pneumococcal infection is one of the major causes of morbidity and mortality among children below 2 years of age in under-developed countries. Current study involves the screening and identification of potent inhibitors of the pneumococcal virulence factor pneumolysin. About 100 flavonoids were chosen from scientific literature and docked with pnuemolysin (PDB Id.: 4QQA) using Patch Dockprogram for molecular docking. The results obtained were analysed and the docked structures visualized using LigPlus software. It was found that flavonoids amurensin, diosmin, robinin, rutin, sophoroflavonoloside, spiraeoside and icariin had hydrogen bond interactions with the receptor protein pneumolysin (4QQA). Among others, robinin had the highest score (7710) revealing that it had the best geometrical fit to the receptor molecule forming 12 hydrogen bonds ranging from 0.8-3.3 Å. Keywords : Pneumococci, pneumolysin, flavonoids, antimicrobial, virtual screening _____________________________________________________________________________________________ INTRODUCTION Streptococcus pneumoniae is a gram positive pathogenic bacterium causing opportunistic infections that may be life-threating[1]. Pneumococcus is the causative agent of pneumonia and is the most common agent causing meningitis.
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  • Redalyc.Reactivity Indexes and O-H Bond Dissociation Energies of A
    Journal of the Mexican Chemical Society ISSN: 1870-249X [email protected] Sociedad Química de México México Pérez-González, Adriana; Rebollar-Zepeda, Aida Mariana; León-Carmona, Jorge Rafael; Galano, Annia Reactivity Indexes and O-H Bond Dissociation Energies of a Large Series of Polyphenols: Implications for their Free Radical Scavenging Activity Journal of the Mexican Chemical Society, vol. 56, núm. 3, julio-septiembre, 2012, pp. 241-249 Sociedad Química de México Distrito Federal, México Available in: http://www.redalyc.org/articulo.oa?id=47524533003 How to cite Complete issue Scientific Information System More information about this article Network of Scientific Journals from Latin America, the Caribbean, Spain and Portugal Journal's homepage in redalyc.org Non-profit academic project, developed under the open access initiative J. Mex. Chem. Soc. 2012, 56(3), 241-249 ArticleReactivity Indexes and O-H Bond Dissociation Energies of a Large Series of Polyphenols: Implications ©for 2012, their SociedadFree Radical Química de México241 ISSN 1870-249X Reactivity Indexes and O-H Bond Dissociation Energies of a Large Series of Polyphenols: Implications for their Free Radical Scavenging Activity Adriana Pérez-González, Aida Mariana Rebollar-Zepeda, Jorge Rafael León-Carmona, and Annia Galano∗ Departamento de Química. Universidad Autónoma Metropolitana-Iztapalapa. San Rafael Atlixco 186, Col. Vicentina. Iztapalapa. C. P. 09340. México D. F. México. [email protected] To Professor José Luis Gázquez Mateos for being a great example and a constant motivation. We sincerely thank him for sharing his kindness and knowledge with all of us. Received September 19, 2011; accepted February 20, 2012 Abstract. Several chemical descriptors have been evaluated for thirty Resumen.
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  • Ep 3138585 A1
    (19) TZZ¥_¥_T (11) EP 3 138 585 A1 (12) EUROPEAN PATENT APPLICATION (43) Date of publication: (51) Int Cl.: 08.03.2017 Bulletin 2017/10 A61L 27/20 (2006.01) A61L 27/54 (2006.01) A61L 27/52 (2006.01) (21) Application number: 16191450.2 (22) Date of filing: 13.01.2011 (84) Designated Contracting States: (72) Inventors: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB • Gousse, Cecile GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO 74230 Dingy Saint Clair (FR) PL PT RO RS SE SI SK SM TR • Lebreton, Pierre Designated Extension States: 74000 Annecy (FR) BA ME •Prost,Nicloas 69440 Mornant (FR) (30) Priority: 13.01.2010 US 687048 26.02.2010 US 714377 (74) Representative: Hoffmann Eitle 30.11.2010 US 956542 Patent- und Rechtsanwälte PartmbB Arabellastraße 30 (62) Document number(s) of the earlier application(s) in 81925 München (DE) accordance with Art. 76 EPC: 15178823.9 / 2 959 923 Remarks: 11709184.3 / 2 523 701 This application was filed on 29-09-2016 as a divisional application to the application mentioned (71) Applicant: Allergan Industrie, SAS under INID code 62. 74370 Pringy (FR) (54) STABLE HYDROGEL COMPOSITIONS INCLUDING ADDITIVES (57) The present specification generally relates to hydrogel compositions and methods of treating a soft tissue condition using such hydrogel compositions. EP 3 138 585 A1 Printed by Jouve, 75001 PARIS (FR) EP 3 138 585 A1 Description CROSS REFERENCE 5 [0001] This patent application is a continuation-in-part of U.S.
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