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Supplement 1A Steffensen Et Liver Wild-type Knockout C T C T 1 2 4 7 8 9 1 2 4 5 7 9 1 1 1 1 1 1 C C C T T T C C C T T T W W W W W W K K K K K K IMAGE:793166 RIKEN cDNA 6720463E02 gene IMAGE:1447421 ESTs, Weakly similar to ZF37 MOUSE ZINC FINGER PROTEIN 37 [M.musculus] IMAGE:934291 RIKEN cDNA 2810418N01 gene IMAGE:1247525 small EDRK-rich f2actor IMAGE:1449402 expressed sequence AW321064 IMAGE:1279847 ESTs IMAGE:518737 expressed sequence AW049941 IMAGE:860231 a disintegrin and metalloproteinase domain 17 IMAGE:642836 CD86 antigen IMAGE:1003885 phosphoribosyl pyrophosphate sy1nthetase IMAGE:524862 RIKEN cDNA 5730469D23 gene IMAGE:1264473 protein inhibitor of activat1ed STAT IMAGE:847035 RIKEN cDNA 4833422F06 gene IMAGE:374550 requiem IMAGE:976520 nuclear receptor coact4ivator IMAGE:1264311 Unknown IMAGE:976735 expressed sequence AI987692 IMAGE:976659 cathepsLin IMAGE:1477580 RIKEN cDNA 1600010J02 gene IMAGE:1277168 ribosomal protein, large, P1 IMAGE:524842 RIKEN cDNA 0710008D09 gene IMAGE:373019 split hand/foot delete1d gene IMAGE:404428 expressed sequence AI413851 IMAGE:619810 RIKEN cDNA 1700003F10 gene IMAGE:1749558 caspase 3, apoptosis related cysteine protease IMAGE:718718 RIKEN cDNA 2810003F23 gene IMAGE:819789 Unknown IMAGE:524474 ATP-binding cassette, sub-family A ABC1, member IMAGE:804950 Mus musculus, Similar to ribosomal protein S20, clone MGC:6876 IMAGE:2651405, mRNA, complete cds IMAGE:806143 gap junction membrane channel prot2ein beta IMAGE:1745887 expressed sequence AI836376 IMAGE:779426 RIKEN cDNA 5230400G24 gene IMAGE:1125615 Unknown IMAGE:535025 DNA segment, Chr 10, University of California at 1Los Angeles IMAGE:540395 proteasome prosome, macropain subunit, a6lpha type IMAGE:792016 Down syndrome critical regiocn gene IMAGE:536637 Unknown IMAGE:1259879 programmed cell 6death IMAGE:793037 ribosomal protein S5 IMAGE:1038936 ribosomal protein S7 IMAGE:988801 eukaryotic translation initiation factor 4A2 IMAGE:539903 E4F transcription f1actor IMAGE:403969 ribosomal protein L7 IMAGE:1276747 Unknown IMAGE:1066664 phosphodiesterase 8A IMAGE:902529 RIKEN cDNA 0910001K20 gene IMAGE:515271 ESTs IMAGE:865071 serine/arginine repetitive 1matrix IMAGE:387840 peroxiredo2xin IMAGE:1227243 peroxiredo2xin IMAGE:1004953 proteasome prosome, macropain subunit, 4beta type IMAGE:1209161 ribosomal protein L10A IMAGE:1125498 torsin family 1, mBember IMAGE:1193024 transcriptional regulator, SIN3B yeast IMAGE:538685 RIKEN cDNA 1500010B24 gene IMAGE:1037871 polyrC binding pr2otein IMAGE:1037829 Unknown IMAGE:517398 expressed sequence C79540 IMAGE:539693 transcription factor A, mitochondrial IMAGE:806050 expressed sequence N28169 IMAGE:1037547 RIKEN cDNA 1300003P13 gene IMAGE:523992 Unknown IMAGE:1005368 RIKEN cDNA 0610037M02 gene IMAGE:865319 RIKEN cDNA 4733401P19 gene IMAGE:791361 RIKEN cDNA 2610025M23 gene IMAGE:596277 zinc finger protein 103 IMAGE:1038497 sorting ne4xin IMAGE:1106517 Unknown IMAGE:536865 adenylosuccinate synthetase 2, non muscle IMAGE:540910 ESTs IMAGE:765554 catenin cadherin-associated protein, delta 2 neural plakophilin-related arm-repeat protein IMAGE:318345 ribosomal protein L12 IMAGE:523285 myotubularin related p1rotein IMAGE:335326 amelogenin IMAGE:524176 carbohydrate sulfotrans2ferase IMAGE:535262 expressed sequence C87006 IMAGE:865421 RIKEN cDNA 1110021D01 gene IMAGE:1382673 eukaryotic translation initiation factor 3, subunit 2 beta, 36kD IMAGE:963268 mannose-P-dolichol utilization1 defect IMAGE:1005605 ESTs, Weakly similar to AF069992 1 LIM domain interacting RING finger protein [M.musculus] IMAGE:822470 ethanol indu6ced IMAGE:976890 isocitrate dehydrogenase 2 NADP+, mitochondrial IMAGE:515500 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c sub1unit 9, isoform IMAGE:535906 5, 10-methenyltetrahydrofolate synthetase IMAGE:550898 proteasome prosome, macropain subunit, a7lpha type IMAGE:1004778 Unknown IMAGE:977312 spastic paraplegia 4 homolog human IMAGE:658891 Wnt inhibitory fa1ctor IMAGE:1004045 RIKEN cDNA 1110036B12 gene IMAGE:520661 phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide IMAGE:1281405 vascular endothelial zinc 1finger IMAGE:778524 RIKEN cDNA 5930415H02 gene IMAGE:524664 palate, lung, and nasal epithelium expressed transcript IMAGE:872984 RIKEN cDNA 2700038I16 gene IMAGE:653189 RIKEN cDNA 1300018J18 gene IMAGE:778523 adaptor-related protein complex 2, beta 1 subunit IMAGE:976761 RIKEN cDNA 4430402G14 gene IMAGE:1005899 actin-like IMAGE:1222999 thioredo1xin IMAGE:1261464 RIKEN cDNA 3110001O07 gene IMAGE:644118 CD163 antigen IMAGE:1149166 ESTs IMAGE:518883 cytochrome P450, 4a14 IMAGE:575780 ESTs IMAGE:865415 Mus musculus TOB3 mRNA, complete cds IMAGE:477770 mitochondrial ribosomal protein L17 IMAGE:1382734 ESTs IMAGE:1134592 bone morphogenic protein receptor, type II serine/threonine kinase IMAGE:1383858 ESTs, Weakly similar to YAE6_YEAST HYPOTHETICAL 13.4 KD PROTEIN IN ACS1-GCV3 INTERGENIC REGION [S.cerevisiae] IMAGE:635786 ESTs IMAGE:1001397 UDP-glucose ceramide glucosyltransferase-like IMAGE:959756 Unknown IMAGE:988484 Mus musculus, clone MGC:31290 IMAGE:4219375, mRNA, complete cds IMAGE:520320 RIKEN cDNA 5031401C21 gene IMAGE:522797 RIKEN cDNA 5031422I09 gene IMAGE:313842 ESTs IMAGE:520613 esterase 10 IMAGE:539629 COP9 constitutive photomorphogenic homolog, subunit 5 Arabidopsis thaliana IMAGE:987831 phenylalkylamine Ca2+ antagonist emopamil binding protein IMAGE:1382651 COP9 constitutive photomorphogenic homolog, subunit 2 Arabidopsis thaliana IMAGE:523133 RIKEN cDNA 5830455K21 gene IMAGE:638441 platelet derived growth factor, B polypeptide IMAGE:1137247 expressed sequence AW210570 IMAGE:619232 RIKEN cDNA 2010013M14 gene IMAGE:976859 ribosomal protein S17 IMAGE:636517 ganglioside-induced differentiation-associat3ed-protein IMAGE:1038921 procollagen, type V, 2alpha IMAGE:1068060 expressed sequence AW559012 IMAGE:571219 Unknown IMAGE:870901 mannose receptor, C1 type IMAGE:1111102 SH3 domain pro3tein IMAGE:418564 axin2 IMAGE:426212 expressed sequence AI425999 IMAGE:621671 RIKEN cDNA 1110007A04 gene IMAGE:865208 heat shock 10 kDa protein 1 chaperonin 10 IMAGE:1276978 hemochromatosis IMAGE:765294 interferon-g induced GTPase IMAGE:1193486 signal transducer and activator of tran1scription IMAGE:776163 expressed sequence C85356 IMAGE:681449 proteasome prosome, macropain 26S subunit, n4on-ATPase, IMAGE:1005857 prosaposin IMAGE:748650 carbonic anhydrase 5a, mitochondrial IMAGE:535029 poly A polymerase alpha IMAGE:934399 phosphatidic acid phosphatase type 2B IMAGE:1092978 apolipoprotein A-V IMAGE:790431 solute carrier family 22 organic cation transpor5ter, member IMAGE:719964 peroxisome proliferative activated receptor, gamma, 1coactivator IMAGE:517569 RIKEN cDNA 1300004O04 gene IMAGE:1345705 dipeptidylpepti4dase IMAGE:1227633 carboxyleste3rase IMAGE:1332649 zinc finger prolifer1ation IMAGE:520056 expressed sequence AU015315 IMAGE:516646 Mus musculus, Similar to hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/aetnaosyel -tCroiefnuznycmtei oAn ahly dprrotein, beta subunit, clone MGC:7126 IMAGE:3158015, mRNA, complete cds IMAGE:517625 solute carrier family 2 facilitated glucose transpor4ter, member IMAGE:1384125 proline rich protein expressed in brain IMAGE:524388 Unknown IMAGE:523990 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial IMAGE:1092244 cytochrome P450, 4a10 IMAGE:518930 Unknown IMAGE:368571 L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain IMAGE:722501 transducin-like enhancer of split 3, homolog of Drosophila Espl IMAGE:717625 Fc receptor, IgE, low affinity II, alpha polypeptide IMAGE:335781 actinin al2pha IMAGE:1384169 flavin containing monooxy1genase IMAGE:774928 aristaless related homeobox gene Drosophila IMAGE:907211 Mus musculus, Similar to F-box only protein 21, clone MGC:28066 IMAGE:3709413, mRNA, complete cds IMAGE:1227434 expressed sequence AA409584 IMAGE:1262735 2-hydroxyphytanoyl-CoA lyase IMAGE:2101335 carnitine palmitoyltrans2ferase IMAGE:524966 Unknown IMAGE:1495918 tumor protein D521-like IMAGE:642511 complement component 1, q subcomponent binding protein IMAGE:988764 GTP cyclohydro1lase IMAGE:583033 expressed sequence AW124722 IMAGE:313629 Mus musculus, clone MGC:18730 IMAGE:3980676, mRNA, complete cds IMAGE:350310 RAR-related orphan receptor alpha IMAGE:836320 SEC23A S. cerevisiae IMAGE:678570 RIKEN cDNA 2610039E05 gene IMAGE:679213 ESTs IMAGE:352598 RIKEN cDNA 5730405D16 gene IMAGE:959635 calpain 10 IMAGE:642415 RIKEN cDNA 1700026N20 gene IMAGE:720884 ESTs, Weakly similar to T25148 hypothetical protein VT23B5.2 - Caenorhabditis elegans [C.elegans] IMAGE:933700 cellular repressor of E1A-stimulated genes IMAGE:1227154 proteasome prosome, macropain subunit, a3lpha type IMAGE:1429281 zinc finger protein, subfam4ily 1A, IMAGE:1005904 RIKEN cDNA 3010027G13 gene IMAGE:908565 expressed sequence AI834976 IMAGE:1384195 cytochrome P450, subfamily IV B, pol1ypeptide IMAGE:935589 Williams-Beuren syndrome chromosome region 14 homolog human IMAGE:1247426 RIKEN cDNA 1110018O12 gene IMAGE:902193 death-associated k2inase IMAGE:313248 3-hydroxy-3-methylglutaryl-Coenzyme A lyase IMAGE:1383654 ESTs, Weakly similar to G02273 LIV-1 protein [H.sapiens] IMAGE:1150770 annexin A5 IMAGE:847445 RIKEN cDNA 1500031O19 gene IMAGE:1139752 expressed sequence AI118514 IMAGE:640707 RIKEN cDNA 6330414G21 gene IMAGE:1149658 clathrin, light polypeptide Lca IMAGE:403259 huntingtin-associated p1rotein IMAGE:989093 eukaryotic translation initiation factor 4A1 IMAGE:1107314 RIKEN cDNA 0610038L10 gene IMAGE:944309 ESTs, Highly similar to JC5511 TATA-binding protein-associated
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