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Clinicopathological Features of Annular Elastolytic Giant Cell
Original Investigation / Özgün Araştırma Turk J Dermatol 2018;12:85-9 • DOI: 10.4274/tdd.3409 85 Hilal Kaya Clinicopathological Features of Annular Erdoğan, Deniz Arık*, Elastolytic Giant Cell Granuloma Patients Ersoy Acer, Evrim Yılmaz*, Anüler Elastolitik Dev Hücreli Granülom Zeynep Nurhan Hastalarının Klinikopatolojik Özellikleri Saraçoğlu Abstract Objective: Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous disease characterized by annular plaques. In this study, we aimed to describe the clinical and pathological features of the patients diagnosed with AEGCG. Methods: The demographic, clinical and pathological features of patients who diagnosed with AEGCG were recorded retrospectively. Results: Ten patients with AEGCG included in the study (nine females and one male). The mean age of the patients was 60±9.53 years. The mean duration of disease was 24.2±36.30 months. On dermatologic examination, multiple, well-demarcated, elevated borders and central atrophic erythematous annular plaques were seen in all patients. In the most of the patients (90%) lesions were on the sun-exposed regions. Six of the patients had accompanying diseases. Histopathologic examination of the punch biopsies revealed foreign body type multinucleated giant cells and lymphocytic cell infiltration in the dermis. There were intracellular elastic fiber fragments as sign of elastophagocytosis in the giant cells. Conclusion: AEGCG is a rare granulomatous disease which can accompany various diseases. There is debate on the terminology, classification and pathogenesis. Further studies are required to elucidate the unknowns. Keywords: Annular elastolytic giant cell granuloma, elastophagocytosis, granulomatous diseases, elastolysis, giant cell, granuloma annulare Eskişehir Osmangazi University Faculty of Medicine, Öz Department of Dermatology and Venereology, Amaç: Anüler elastolitik dev hücreli granülom (AEDHG), anüler plaklar ile karakterize, Eskişehir, Turkey nadir granülomatöz bir hastalıktır. -
(CD-P-PH/PHO) Report Classification/Justifica
COMMITTEE OF EXPERTS ON THE CLASSIFICATION OF MEDICINES AS REGARDS THEIR SUPPLY (CD-P-PH/PHO) Report classification/justification of medicines belonging to the ATC group D07A (Corticosteroids, Plain) Table of Contents Page INTRODUCTION 4 DISCLAIMER 6 GLOSSARY OF TERMS USED IN THIS DOCUMENT 7 ACTIVE SUBSTANCES Methylprednisolone (ATC: D07AA01) 8 Hydrocortisone (ATC: D07AA02) 9 Prednisolone (ATC: D07AA03) 11 Clobetasone (ATC: D07AB01) 13 Hydrocortisone butyrate (ATC: D07AB02) 16 Flumetasone (ATC: D07AB03) 18 Fluocortin (ATC: D07AB04) 21 Fluperolone (ATC: D07AB05) 22 Fluorometholone (ATC: D07AB06) 23 Fluprednidene (ATC: D07AB07) 24 Desonide (ATC: D07AB08) 25 Triamcinolone (ATC: D07AB09) 27 Alclometasone (ATC: D07AB10) 29 Hydrocortisone buteprate (ATC: D07AB11) 31 Dexamethasone (ATC: D07AB19) 32 Clocortolone (ATC: D07AB21) 34 Combinations of Corticosteroids (ATC: D07AB30) 35 Betamethasone (ATC: D07AC01) 36 Fluclorolone (ATC: D07AC02) 39 Desoximetasone (ATC: D07AC03) 40 Fluocinolone Acetonide (ATC: D07AC04) 43 Fluocortolone (ATC: D07AC05) 46 2 Diflucortolone (ATC: D07AC06) 47 Fludroxycortide (ATC: D07AC07) 50 Fluocinonide (ATC: D07AC08) 51 Budesonide (ATC: D07AC09) 54 Diflorasone (ATC: D07AC10) 55 Amcinonide (ATC: D07AC11) 56 Halometasone (ATC: D07AC12) 57 Mometasone (ATC: D07AC13) 58 Methylprednisolone Aceponate (ATC: D07AC14) 62 Beclometasone (ATC: D07AC15) 65 Hydrocortisone Aceponate (ATC: D07AC16) 68 Fluticasone (ATC: D07AC17) 69 Prednicarbate (ATC: D07AC18) 73 Difluprednate (ATC: D07AC19) 76 Ulobetasol (ATC: D07AC21) 77 Clobetasol (ATC: D07AD01) 78 Halcinonide (ATC: D07AD02) 81 LIST OF AUTHORS 82 3 INTRODUCTION The availability of medicines with or without a medical prescription has implications on patient safety, accessibility of medicines to patients and responsible management of healthcare expenditure. The decision on prescription status and related supply conditions is a core competency of national health authorities. -
Granuloma Annulare: Not As Simple As It Seems
Thomas Jefferson University Jefferson Digital Commons Department of Dermatology and Cutaneous Department of Dermatology and Cutaneous Biology Faculty Papers Biology 9-1-2010 Granuloma annulare: not as simple as it seems. Lawrence Charles Parish Thomas Jefferson University Joseph A. Witkowski University of Pennsylvania School of Medicine Follow this and additional works at: https://jdc.jefferson.edu/dcbfp Part of the Dermatology Commons Let us know how access to this document benefits ouy Recommended Citation Parish, Lawrence Charles and Witkowski, Joseph A., "Granuloma annulare: not as simple as it seems." (2010). Department of Dermatology and Cutaneous Biology Faculty Papers. Paper 76. https://jdc.jefferson.edu/dcbfp/76 This Article is brought to you for free and open access by the Jefferson Digital Commons. The Jefferson Digital Commons is a service of Thomas Jefferson University's Center for Teaching and Learning (CTL). The Commons is a showcase for Jefferson books and journals, peer-reviewed scholarly publications, unique historical collections from the University archives, and teaching tools. The Jefferson Digital Commons allows researchers and interested readers anywhere in the world to learn about and keep up to date with Jefferson scholarship. This article has been accepted for inclusion in Department of Dermatology and Cutaneous Biology Faculty Papers by an authorized administrator of the Jefferson Digital Commons. For more information, please contact: [email protected]. Granuloma Annulare: Not as simple as -
C.O.E. Continuing Education Curriculum Coordinator
CONTINUING EDUCATION All Rights Reserved. Materials may not be copied, edited, reproduced, distributed, imitated in any way without written permission from C.O. E. Continuing Education. The course provided was prepared by C.O.E. Continuing Education Curriculum Coordinator. It is not meant to provide medical, legal or C.O.E. professional services advice. If necessary, it is recommended that you consult a medical, legal or professional services expert licensed in your state. Page 1 of 199 Click Here To Take Test Now (Complete the Reading Material first then click on the Take Test Now Button to start the test. Test is at the bottom of this page) 5 hr. Nail Structure and Growth & TCSG Health and Safety Outline Why Study Nail Structure and Growth? • The Natural Nail • Nail Anatomy • Nail Growth • Know Your Nails Objectives After completing this section, you should be able to: C.O.E.• Describe CONTINUING the structure and composition of nails. EDUCATION • Discuss how nails grow. • Identify diseases and disorders of the nail All Rights Reserved. Materials may not be copied, edited, reproduced, distributed, imitated in any way without written permission from C.O. E. Continuing Education. The course provided was prepared by C.O.E. Continuing Education Curriculum Coordinator. It is not meant to provide medical, legal or professional services advice. If necessary, it is recommended that you consult a medical, legal or professional services expert licensed in your state. 1 CONTINUING EDUCATION All Rights Reserved. Materials may not be copied, edited, reproduced, distributed, imitated in any way without written permission from C.O. -
General Dermatology an Atlas of Diagnosis and Management 2007
An Atlas of Diagnosis and Management GENERAL DERMATOLOGY John SC English, FRCP Department of Dermatology Queen's Medical Centre Nottingham University Hospitals NHS Trust Nottingham, UK CLINICAL PUBLISHING OXFORD Clinical Publishing An imprint of Atlas Medical Publishing Ltd Oxford Centre for Innovation Mill Street, Oxford OX2 0JX, UK tel: +44 1865 811116 fax: +44 1865 251550 email: [email protected] web: www.clinicalpublishing.co.uk Distributed in USA and Canada by: Clinical Publishing 30 Amberwood Parkway Ashland OH 44805 USA tel: 800-247-6553 (toll free within US and Canada) fax: 419-281-6883 email: [email protected] Distributed in UK and Rest of World by: Marston Book Services Ltd PO Box 269 Abingdon Oxon OX14 4YN UK tel: +44 1235 465500 fax: +44 1235 465555 email: [email protected] © Atlas Medical Publishing Ltd 2007 First published 2007 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, without the prior permission in writing of Clinical Publishing or Atlas Medical Publishing Ltd. Although every effort has been made to ensure that all owners of copyright material have been acknowledged in this publication, we would be glad to acknowledge in subsequent reprints or editions any omissions brought to our attention. A catalogue record of this book is available from the British Library ISBN-13 978 1 904392 76 7 Electronic ISBN 978 1 84692 568 9 The publisher makes no representation, express or implied, that the dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up-to-date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. -
Eradication of Staphylococcus Aureus and MRSA in the Nares: a Historical Perspective of the Ecological Niche, with Suggestions for Future Therapy Considerations
Advances in Microbiology, 2017, 7, 420-449 http://www.scirp.org/journal/aim ISSN Online: 2165-3410 ISSN Print: 2165-3402 Eradication of Staphylococcus aureus and MRSA in the Nares: A Historical Perspective of the Ecological Niche, with Suggestions for Future Therapy Considerations Eric Bornstein Nomir Medical Technologies, Woodmere, NY, USA How to cite this paper: Bornstein, E. (2017) Abstract Eradication of Staphylococcus aureus and MRSA in the Nares: A Historical Perspec- Nasal colonization with pathogenic bacteria continues to present challenges for tive of the Ecological Niche, with Sugges- patients undergoing surgical procedures, and for the physicians that treat them. tions for Future Therapy Considerations. Advances in Microbiology, 7, 420-449. Even as molecular medicine produces ever faster and improved data sets for cli- https://doi.org/10.4236/aim.2017.76034 nicians, it would benefit all medical personnel attempting to decolonize the nose to better understand the historical nasal decolonization data with specific refer- Received: April 28, 2017 ence to the ecological niche for these bacteria, as it has been recorded for more Accepted: June 12, 2017 Published: June 15, 2017 than a century. Much of the historical data points to the largest ecological niche for nasal Staphylococcus aureus as the vibrissae of the vestibulum nasi. A careful Copyright © 2017 by author and study shows that any topical antimicrobial preparation needs to successfully Scientific Research Publishing Inc. This work is licensed under the Creative penetrate the deepest recesses of these specialized nasal hair follicles, if decolo- Commons Attribution International nization is to be adequately accomplished. This review highlights the most rele- License (CC BY 4.0). -
Module Test № 1 on Dermatology
THE MINISTRY OF HEALTHCARE OF THE RUSSIAN FEDERATION FEDERAL STATE BUDGETARY EDUCATIONAL INSTITUTION OF HIGHER PROFESSIONAL EDUCATION PIROGOV RUSSIAN NATIONAL RESEARCH MEDICAL UNIVERSITY DEPARTMENT OF DERMATOVENEROLOGY Gaydina T.A., Dvornikov A.S., Skripkina P.A., Nazhmutdinova D.K., Heydar S.A., Arutunyan G.B., Pashinyan A.G. MODULE TEST №1 ON DERMATOLOGY FOR STUDENTS OF INSTITUTES OF HIGHER MEDICAL EDUCATION ON SPECIALTY THERAPEUTIC FACULTY DEPARTMENT OF DERMATOVENEROLOGY Moscow 2016 ISBN УДК ББК A21 Module test №1 on Dermatology for students of institutes of high medical education on specialty «Therapeutic faculty» department of dermatovenerology: manual for students for self-training//FSBEI HPE “Pirogov RNRMU” of the ministry of healthcare of the russian federation, M.: (publisher) 2016, 144 p. The manual is a part of teaching-methods on Dermatovenerology. It contains tests on Dermatology on the topics of practical sessions requiring single or multiple choice anser. The manual can be used to develop skills of students during practical sessions. It also can be used in the electronic version at testing for knowledge. The manual is compiled according to FSES on specialty “therapeutic faculty”, working programs on dermatovenerology. The manual is intended for foreign students of 3-4 courses on specialty “therapeutic faculty” and physicians for professional retraining. Authors: Gaydina T.A. – candidate of medical science, assistant of dermatovenerology department of therapeutic faculty Pirogov RNRMU Dvornikov A.S. – M.D., professor of dermatovenerology department of therapeutic faculty Pirogov RNRMU Skripkina P.A. – candidate of medical science, assistant professor of dermatovenerology department of therapeutic faculty Pirogov RNRMU Nazhmutdinova D.K. – candidate of medical science, assistant professor of dermatovenerology department of therapeutic faculty Pirogov RNRMU Heydar S.A. -
“A Clinical Study of Antimiasmatic Treatment on Patients with Haemorrhoids”
“A CLINICAL STUDY OF ANTIMIASMATIC TREATMENT ON PATIENTS WITH HAEMORRHOIDS” A DISSERTATION SUBMITTED IN PARTIAL FULFILLMENT OF THE REQUIREMENT FOR THE AWARD OF THE DEGREE OF DOCTOR OF MEDICINE IN HOMOEOPATHY: M.D. (HOM.) IN ORGANON OF MEDICINE AND HOMOEOPATHIC PHILOSOPHY By Dr. DIVYA PUSHPARAJ UNDER THE GUIDANCE OF Dr. MANOJ NARAYAN V., M.D. (HOM.) PROFESSOR DEPARTMENT OF ORGANON OF MEDICINE & HOMOEOPATHIC PHILOSOPHY SARADA KRISHNA HOMOEOPATHIC MEDICAL COLLEGE, KULASEKHARAM, TAMILNADU. SUBMITTED TO THE TAMILNADU Dr. MGR MEDICAL UNIVERSITY, CHENNAI. 2019 ENDORSEMENT BY THE HEAD OF THE DEPARTMENT AND THE INSTITUTION This is to certify that the dissertation entitled, “A CLINICAL STUDY OF ANTIMIASMATIC TREATMENT ON PATIENTS WITH HAEMORRHOIDS” is a bonafide work carried out by Dr. DIVYA PUSHPARAJ, a student of M.D. (Hom.) in the DEPARTMENT OF ORGANON OF MEDICINE AND HOMOEOPATHIC PHILOSOPHY in SARADA KRISHNA HOMOEOPATHIC MEDICAL COLLEGE under the supervision and guidance of Prof. Dr. MANOJ NARAYAN V., M.D. (Hom.), PROFESSOR, DEPT. OF ORGANON OF MEDICINE & HOMOEOPATHIC PHILOSOPHY in partial fulfilment of the regulations for the award of the Degree of DOCTOR OF MEDICINE (HOMOEOPATHY) in ORGANON OF MEDICINE AND HOMOEOPATHIC PHILOSOPHY. This work conforms to the standards prescribed by THE TAMILNADU DR. MGR MEDICAL UNIVERSITY, CHENNAI. This has not been submitted in full or part for the award of any degree or diploma from any University. Dr. M. MURUGAN, M.D. (HOM.) Dr. N. V. SUGATHAN, M.D. (HOM.) Professor & Head, Principal Department of Organon of Medicine & Homoeopathic Philosophy Place: Kulasekharam Date: CERTIFICATE BY THE GUIDE This is to certify that the dissertation entitled, “A CLINICAL STUDY OF ANTIMIASMATIC TREATMENT ON PATIENTS WITH HAEMORRHOIDS” is a bonafide work of Dr. -
Steroid-Induced Rosacealike Dermatitis: Case Report and Review of the Literature
CONTINUING MEDICAL EDUCATION Steroid-Induced Rosacealike Dermatitis: Case Report and Review of the Literature Amy Y-Y Chen, MD; Matthew J. Zirwas, MD RELEASE DATE: April 2009 TERMINATION DATE: April 2010 The estimated time to complete this activity is 1 hour. GOAL To understand steroid-induced rosacealike dermatitis (SIRD) to better manage patients with the condition LEARNING OBJECTIVES Upon completion of this activity, dermatologists and general practitioners should be able to: 1. Explain the clinical features of SIRD, including the 3 subtypes. 2. Evaluate the multifactorial pathogenesis of SIRD. 3. Recognize the importance of a detailed patient history and physical examination to diagnose SIRD. INTENDED AUDIENCE This CME activity is designed for dermatologists and generalists. CME Test and Instructions on page 195. This article has been peer reviewed and approved Einstein College of Medicine is accredited by by Michael Fisher, MD, Professor of Medicine, the ACCME to provide continuing medical edu- Albert Einstein College of Medicine. Review date: cation for physicians. March 2009. Albert Einstein College of Medicine designates This activity has been planned and imple- this educational activity for a maximum of 1 AMA mented in accordance with the Essential Areas PRA Category 1 Credit TM. Physicians should only and Policies of the Accreditation Council for claim credit commensurate with the extent of their Continuing Medical Education through the participation in the activity. joint sponsorship of Albert Einstein College of This activity has been planned and produced in Medicine and Quadrant HealthCom, Inc. Albert accordance with ACCME Essentials. Dr. Chen owns stock in Merck & Co, Inc. Dr. Zirwas is a consultant for Coria Laboratories, Ltd, and is on the speakers bureau for Astellas Pharma, Inc, and Coria Laboratories, Ltd. -
Common Dermatological Conditions
Produced: 13/01/2017 Common Dermatological Conditions Dr Alvin Chong Senior Lecturer Dr Catherine Scarff Senior Lecturer Dr Laura Scardamaglia Clinical Senior Lecturer Produced: 13/01/2017 Learning objectives: Describe the common features of • Eczema variants and psoriasis • Acne and rosacea • Scabies • Understand the principles of investigation and treatment for common dermatological problems Produced: 13/01/2017 Case: A 22 year old student presents with 3 months of worsening rash. Not responding to 1% hydrocortisone cream. Produced: 13/01/2017 Erythematous, ill defined, scaly, patches in flexures Produced: 13/01/2017 Diagnosis: Atopic eczema Produced: 13/01/2017 Atopic Eczema • Genetic predisposition Clinical features (Family history) • Itchy ++ • Atopic triad • Erythematous - Asthma • Diffuse - Hayfever • Flexural- thinnest skin - Eczema • Worse in winter (dry) • Worse in summer (heat) Produced: 13/01/2017 Atopic Eczema Model Genetic Predisposition Environmental -Filaggrin mutation- Triggers Leads to reduced barrier •Irritants (soaps etc) function •Allergy •Heat •Infection (Staph.) •“Itch-scratch cycle” •Stress and anxiety 1. Palmer et al Nat. Genet. 38,441-6 Eczema Produced: 13/01/2017 Atopic eczema in an infant Produced: 13/01/2017 3 year old girl, eczema since infancy Produced: 13/01/2017 35 year old man with longstanding eczema mainly of the flexures. Produced: 13/01/2017 Lichenification: The result of chronic rubbing and scratching Produced: 13/01/2017 Eczema Variants Produced: 13/01/2017 Discoid Eczema • Eczema in annular disc -
Painful Penile Indurations and Homoeopathy
Dr. Rajneesh Kumar Sharma Painful Penile MD (Homoeopathy) Indurations and Homoeopathy Painful Penile Indurations and Homoeopathy Painful Penile Indurations and Homoeopathy © Dr. Rajneesh Kumar Sharma BSc, BHMS, MD (Homoeopathy), DI (Hom) London, hMD (UK) etc. Homoeo Cure & Research Institute NH 74, Moradabad Road, Kashipur (Uttaranchal) INDIA, Pin- 244713 Ph. 05947- 260327, 9897618594 [email protected], [email protected] www.cureme.org.in, www.treatmenthomeopathy.com, www.homeopathyworldcommunity.com Contents Introduction ................................................................................................................................................... 2 Anatomy ......................................................................................................................................................... 2 Glans ........................................................................................................................................................... 2 Corpus cavernosum ................................................................................................................................ 2 Corpus spongiosum ................................................................................................................................. 2 Urethra ........................................................................................................................................................ 2 Peyronie Disease ......................................................................................................................................... -
Krok 2. Medicine
Sample test questions Krok 2 Medicine () Терапевтичний профiль 2 1. A 25-year-old woman has been A. Transfer into the inpatient narcology suffering from diabetes mellitus since she department was 9. She was admitted into the nephrology B. Continue the treatment in the therapeutic unit with significant edemas of the face, arms, department and legs. Blood pressure - 200/110 mm Hg, C. Transfer into the neuroresuscitation Hb- 90 g/L, blood creatinine - 850 mcmol/L, department urine proteins - 1.0 g/L, leukocytes - 10-15 in D. Compulsory medical treatment for the vision field. Glomerular filtration rate - alcoholism 10 mL/min. What tactics should the doctor E. Discharge from the hospital choose? 5. After eating shrimps, a 25-year-old man A. Transfer into the hemodialysis unit suddenly developed skin itching, some areas B. Active conservative therapy for diabetic of his skin became hyperemic or erupted into nephropathy vesicles. Make the diagnosis: C. Dietotherapy D. Transfer into the endocrinology clinic A. Acute urticaria E. Renal transplantation B. Hemorrhagic vasculitis (Henoch-Schonlein purpura) 2. A 59-year-old woman was brought into the C. Urticaria pigmentosa rheumatology unit. Extremely severe case D. Psoriasis of scleroderma is suspected. Objectively she E. Scabies presents with malnourishment, ”mask-like” face, and acro-osteolysis. Blood: erythrocytes 6. A 25-year-old woman complains of fatigue, - 2.2 · 109/L, erythrocyte sedimentation rate - dizziness, hemorrhagic rashes on the skin. 40 mm/hour. Urine: elevated levels of free She has been presenting with these signs for a · 12 oxyproline. Name one of the most likely month.