A Clinical Study to See the Effect of Homoeopathic Medicines in Polycystic Ovarian Syndrome of Reproductive Age Group Between 12-45 Years
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International Journal of Health Sciences and Research Vol.10; Issue: 3; March 2020 Website: www.ijhsr.org Original Research Article ISSN: 2249-9571 A Clinical Study to See the Effect of Homoeopathic Medicines in Polycystic Ovarian Syndrome of Reproductive Age Group between 12-45 Years Priti Ashok.Malvekar1, Sameer S.Nadgauda2, Arun Bhargav Jadhav3 1Post Graduate, 2Assistant Professor, Department of Practice of Medicine, Homoeopathic medical college and Hospital, Dept. Of Postgraduate and Research Centre, Pune-Bangalore Highway, Katraj Dhankawadi, India. 3 Principal, Homoeopathic Medical College and Hospital, Dept. Of Postgraduate and research Centre, Pune- Bangalore Highway, Katraj-Dhankawadi, India. Corresponding Author: Sameer S.Nadgauda ABSTRACT Objective of the study -The present study was single arm, clinical study to determine the role of homoeopathic medicines in regulation of menstrual cycle.30 patient fulfilling the eligibility criteria enrolled in this study was underwent homoeopathic intervention, clinical evaluation and detailed menstrual history at baseline. Results- Out of 30 cases, 14 cases (46.66%) showed good improvement in cases of irregular menses, 21 cases (63.3 3%) showed good improvement in Complaints of acne and 25 cases(83.33%) showed good improvement in cases of health related quality of life related to PCOS. Conclusion-The Homoeopathic medicines showed significant improvement treating PCOS. From the analysis of the above results obtained it is obvious that Homoeopathic treatment is effective in Polycystic Ovarian Syndrome. Cases can be treated successfully by homoeopathic treatment. We should consider mental general and constitution of patient for most similar homoeopathic remedy. Life style modification along with homoeopathic treatment is effective in reducing signs and symptoms of PCOS. Keywords- Homoeopathy, Polycystic Ovaries, Menstrual Irregularity, Polycystic Ovarian Syndrome Questionnaire. INTRODUCTION ordinarily have many number of little cysts Polycystic Ovarian Syndrome around the edge of their ovaries. Polycystic otherwise called PCOS OR PCOD ovaries mean the ovaries containing [Polycystic Ovarian Disorder] is a typical countless blisters that are not greater than hormonal issue and a main source of female 8mm and grow a larger number of follicles infertility around the world. PCOS is consistently than ordinary ovaries. The additionally called as Stein-Leventhal growths are the egg containing follicles that Syndrome after two specialists who don't grow appropriately as a result of originally depicted it in 1935 [1] The hormone imbalance. A few females proceed Rotterdam 2003 criteria characterizes PCOS to create PCOS [Polycystic Ovarian as frequency of any two of 3 key criteria in Syndrome] which implies they have particular, oligoovulation and anovulation, different indications including polycystic hyperandrogenism and polycystic ovaries ovaries. PCOS might be heredity also. [PCO]. [2][3] Poly cystic Ovarian Syndrome Studies shows that ladies with family (PCOS) is a condition wherein females ancestry of polycystic ovaries are half International Journal of Health Sciences and Research (www.ijhsr.org) 43 Vol.10; Issue: 3; March 2020 Priti Ashok. Malvekar et.al. A clinical study to see the effect of homoeopathic medicines in polycystic ovarian syndrome of reproductive age group between 12-45 years bound to create PCOS.PCOS is seen as the Homeopathy directs the menses in most widely recognized explanation behind characteristic manner. Diminishes Hirsutism menstrual abnormalities in 4-12% of ladies (undesirable hairs) and builds the odds of of conceptive age [12-45 yrs. old]. [4][5] 5- considering. PCOS is the most widely 10% of ladies create PCOS during their recognized reason for anovulatory young or youngster bearing years. [6] infertility. There is absence of awareness in Worldwide PCOS influences up to 6-7% of the public about PCOS and its difficulties the populace. In any case, the pervasiveness like fruitlessness, diabetes type 2, explicit to the nation fluctuates widely. In cardiovascular sicknesses. Passionate India, the frequency of PCOS/PCOD is on prosperity issues are critical. [9,10] In the climb; about 35% of ladies experience Allopathy the medications ordinarily the ill effects of it. In 2014 examination led utilized for treatment in ladies with PCOS in Mumbai (independent) among 600 pre- are metformin which can bring down TSH adult young ladies detailed an expected levels and hypothyroidism. commonness of 22.5% when the finding There are scarcely any reports was finished utilizing Rotterdam criteria. showing the convenience of the Another examination was led by All India Homeopathic treatment. Symptomatic just Institutions of Medical Science(AIIMS) it as ultrasonological improvement in PCOS. was discovered that one out of four females Yet, more investigations are required with experience the ill effects of PCOS. appropriate thoroughness. The Respondent population right now to the conceptive age bunch 12-48 MATERIAL AND METHODS years. Most noteworthy number of sufferers Study setting – A clinical study was carried was the understudy classification with out on with detail case study and follow up 21.27% of them experiencing the Disorder. in Bharati Vidyapeeth Medical Foundation’s This demonstrates more young ladies Homoeopathic Hospital, OPD, IPD and with increasingly inclined to hormonal the help of senior Homoeopathic physicians. imbalance. [7] PCOS Present with different Total 30 patients of Reproductive age group level of Symptoms like sporadic, rare between 12-45 yrs. who were suffering from periods inside 3 or 4years of beginning polycystic ovarian syndrome. (PCOS) was discharge lighter overwhelming during enrolled for the study which fulfils the case period, weight gain, and unnecessary hair definition & inclusion /exclusion criteria growth to changing degrees on face, chest, those who were participated willingly in and lower midriff. Moderate stomach research. Since it is a time bound study, inconvenience during periods, skin subject attending, Bharati Vidyapeeth inflammation, and over the top skin Medical Foundation Homoeopathic development on neck or in armpit Hospital, peripheral O.P.D. and various additionally called as acanthosis nigricans. rural and urban camps series. Bone pain [arthralgia] and male pattern Study design – A prospective clinical trial baldness [alopecia], stoppage, flauntulence, interventional single arm single blind and heartburn. Polycystic ovarian disorder method. Study was carried out at Bharati (PCOS) Divided essentially into two types. Vidyapeeth Medical Foundation [8] 1. Insulin Resistant (IR) PCOS. 2. Non- Homoeopathic Hospital, peripheral OPD, Insulin Resistant PCOS. Various rural & urban camp series, OPD, The main cause of PCOS lies in the IPD from 20192020 (Approximately 25 hormonal aggravation. Homeopathy weeks).minimum 30 Cases was selected redresses the hormonal aggravation and which fulfils the case definition & inclusion brings harmony, without the danger of and exclusion criteria those who reaction. It is anyway basic to take participated willingly in the research. Data homeopathic treatment for PCOS. collection was done through Rotterdam International Journal of Health Sciences and Research (www.ijhsr.org) 44 Vol.10; Issue: 3; March 2020 Priti Ashok. Malvekar et.al. A clinical study to see the effect of homoeopathic medicines in polycystic ovarian syndrome of reproductive age group between 12-45 years 2003 criteria as per ASRM (American remedy is already available in the society of reproductive medicine) & Homoeopathic literature, well proved on ESHRE (European society of human healthy human beings and is harmless, reproduction and embryology) guidelines. having no side effects. Intervention Inclusion criteria- inclusion criteria for the Patients fulfilling the eligibility criteria was study are: 1) Female aged 12-45years. 2) enrolled to receive the homoeopathic Oligomenorrhoea (intermenstrual period of intervention. Medicine was given in 30C, more than 35 days for 3 consecutive cycles/ 200C or 1M, LM potency as per the amenorrhea for more than 3 months (2 years prescribing totality. The medicines were after menarche) 3) 3) ultrasound findings of repeated depending on the potency and polycystic ovaries. [11] 4) Clinical evidence complaints of the patient in accordance with of hirsutism (Ferriman score 8 and above) the principles of homoeopathy. [12] and/ or acne (acne global severity scale score 1 and above) [13] 5) Body Mass Index Selection of tool – (BMI) 23 and above. 6) Females who are Drug was acquired from standard pharmacy diagnosed with PCOS. 7) Patient who (SBL Uttarakhand) & was stored as per willing to give written informed consents rules of Homeopathic Pharmacopoeia. for research participation. Medicines was stored in Bharati Vidyapeeth Homoeopathic Pharmacy, Katraj, Pune- Exclusion criteria – 1) Patient with other 411043.Liquid was stored in amber colour systemic illnesses (DM, Cushing syndrome, glass bottle kept in dark place, under hyperprolactenemia. 2) untreated hypo or appropriate temperature, away from hyperthyroidism. 3) Adrenal hyperplasia sunlight& humidity condition. Freshly and adrenal tumour4) ovarian tumour. 5) prepared powder dose was used for Hyperthecosis. 6) History of intake of drugs dispensing purpose. Log no. & Batch no. aldactone/ metformin or history of oral was maintained. contraceptive pills (OCP) use or intake of drugs known to interfere with carbohydrate Brief of procedures- metabolism