PRODUCT DATA SHEET Bioworld Technology,Inc.

ETHE1 polyclonal antibody

Catalog: BS70132 Host: Rabbit Reactivity: Human,Mouse,Rat

BackGround: Purification&Purity: ETHE1 (ethylmalonic encephalopathy 1), also known as The antibody was affinity-purified from rabbit antiserum HSCO (hepatoma subtracted clone one ), is a 254 by affinity-chromatography using epitope-specific im- amino acid protein belonging to the metal- munogen and the purity is > 95% (by SDS-PAGE). lo-beta-lactamase superfamily and glyoxalase II family. Applications: Localizing to the cytoplasm, nucleus and WB 1:200 - 1:1000 matrix, ETHE1 is ubiquitously expressed and may func- Storage&Stability: tion in sulfide catabolism. ETHE1 binds two zinc ions per Store at 4°C short term. Aliquot and store at -20°C long subunit and interacts directly with RELA, preventing its term. Avoid freeze-thaw cycles. localization to the nucleus thus leading to suppressed Specificity: p53-induced apoptosis. The encoding ETHE1 maps ETHE1 polyclonal antibody detects endogenous levels of to human 19q13.31. Mutations to this gene ETHE1 protein. result in ethylmalonic encephalopathy, an infantile meta- DATA: bolic disorder characterized by high levels of ethylmalo- nic acid, neurodevelopmental delay and regression, re- current petechiae, acrocyanosis, and death within the first decade of life. Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide,

50% glycerol, pH7.2 Molecular Weight: Western blot analysis of extracts of various cells, using ETHE1 anti- ~ 28 kDa body. Swiss-Prot: Note: O95571 For research use only, not for use in diagnostic procedure.

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