PRODUCT DATA SHEET Bioworld Technology,Inc. ETHE1 polyclonal antibody Catalog: BS70132 Host: Rabbit Reactivity: Human,Mouse,Rat BackGround: Purification&Purity: ETHE1 (ethylmalonic encephalopathy 1), also known as The antibody was affinity-purified from rabbit antiserum HSCO (hepatoma subtracted clone one protein), is a 254 by affinity-chromatography using epitope-specific im- amino acid protein belonging to the metal- munogen and the purity is > 95% (by SDS-PAGE). lo-beta-lactamase superfamily and glyoxalase II family. Applications: Localizing to the cytoplasm, nucleus and mitochondrion WB 1:200 - 1:1000 matrix, ETHE1 is ubiquitously expressed and may func- Storage&Stability: tion in sulfide catabolism. ETHE1 binds two zinc ions per Store at 4°C short term. Aliquot and store at -20°C long subunit and interacts directly with RELA, preventing its term. Avoid freeze-thaw cycles. localization to the nucleus thus leading to suppressed Specificity: p53-induced apoptosis. The gene encoding ETHE1 maps ETHE1 polyclonal antibody detects endogenous levels of to human chromosome 19q13.31. Mutations to this gene ETHE1 protein. result in ethylmalonic encephalopathy, an infantile meta- DATA: bolic disorder characterized by high levels of ethylmalo- nic acid, neurodevelopmental delay and regression, re- current petechiae, acrocyanosis, and death within the first decade of life. Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Molecular Weight: Western blot analysis of extracts of various cells, using ETHE1 anti- ~ 28 kDa body. Swiss-Prot: Note: O95571 For research use only, not for use in diagnostic procedure. Bioworld Technology, Inc. Bioworld technology, co. Ltd. Add： 1660 South Highway 100, Suite 500 St. Louis Park, Add： No 9, weidi road Qixia District Nanjing, 210046, MN 55416,USA. P. R. China. Email: [email protected] Email: [email protected] Tel: 6123263284 Tel: 0086-025-68037686 Fax: 6122933841 Fax: 0086-025-68035151 .