DÜZCE UNIVERSITY Specialization Studies 2016-2018
Prof. Dr. Nigar Demircan Çakar Rector of Düzce University 12.12.2018 Content (I) 1. Regional Development-Oriented Mission Differentiation 2. Specialization in Health and Environment 3. Initial Studies 4. Specialization in Health: Traditional and Complementary Medicine Cultivation of medicinal plants Beekeeping and bee products Cultivation of medicinal mushrooms Product development activities GTT Polyclinic activities 5. Specialization in Environment: Recycling of Agricultural Wastes Obtainment sustainable material from agricultural wastes Nanocellulose production Nanolignin production Content (II)
6. Physical Structure 7. Projects funded by our University 8. Education and Training Activities 9. Intellectual and Industrial Property 10. Academic Studies 11. 2019… 12. Expected Revenue 13. National and Local Media…
1. Regional Development Oriented Mission Differentiation
With the cooperation of the Council of Higher Education and the Ministry of Development, the program Regional Development-Oriented Mission Differentiation and Specialization was launched for the universities established after 2006 in order to increase the contributions of universities to the region where they are located and to encourage them to specialize in certain areas. In the 2016-2017 Academic Opening Ceremony, the President of the Republic was elected by the five pilot universities, including our university. 2. Specialization in Health and Environment
Health: Traditional and Complementary Medicine
SPECIALIZATION
Environment: Recycling of Agricultural Wastes 3. Initial Studies: Propagation and Informative Meetings
Cumayeri Cilimli Kaynasli Akcakoca Yigilca
Provincial Council Bogaziçi Gumusova Golyaka Musiad In May 2017 the program was introduced in Düzce city center and in all districts, The regional development model by Traditional and Complementary Medicine was explained. 4. Specialization in Health: Traditional and Complementary Medicine Why Traditional and Complementary Medicine?
Since our university was included in the program, the social, technological, economic and environmental factors of our region and the effects of these factors on the university were examined with internal and external stakeholders.
As a result of the evaluations, the natural resources of Düzce and different plant species were found to be a good source for Traditional and Complementary Medicine.
Furthermore, the fact that our university has an academic staff and an important infrastructure that can start to work in this field has played a role in the selection of this area.
Because of the factors such as active participation of local people in the production of materials to be used in Traditional and Complementary Medicine studies, proximity to the metropolises of Ankara and Istanbul, low competitiveness in the fields of modern medicine, etc., Traditional and Complementary Medicine is the most appropriate option in the field of health. Search for Cooperation
Zeytinburnu Medical Bezmialem University Farma Chemicals World Medicine Nobel Pharmaceuticals Plants Garden Phytotherapy Center
Bolu Regional Prof. Dr. İbrahim SBS Bio Solutions Aksu Vital Naturin Directorate of Forestry Saraçoğlu
Studies has been carried out to cooperate with companies and institutions operating in different fields. Villages Visits
Visits were made Koprubasi Elmacik Cinarduzu Ugurlu to the volunteer villages and the program framework and activities to be Dilaver Hemsin Beyoren Saridere carried out within the scope of the program were planned.
Yunusefendi Haciyakup Yesiltepe Dipsizgol Cooperations
Aksu Vital SBS Eğriçayır Bezmialem Mezopotamya Tarım
Aymnet Anatolia Botafarma Saraçoğlu
Melisa Madame Defne Mikrom Naturin Apimaye Seda Tarım Kozmetoloji Traditional and Complementary Medicine Activities
Medicinal / aromatic plant cultivation is carried out in and Medical Plant Breeding around our city, and beekeeping products and medicinal mushroom production are being Beekeeping and Bee Products carried out. In addition, herbal and bee products based health support Medicinal Mushroom Growing products are produced and the private sector cooperates in this field. Product Development It is aimed to increase the health tourism potential of the region with traditional and Applications complementary medicine applications. Medical Plant Breeding
To promote the cultivation of Medicinal-Aromatic Plants within the boundaries of Duzce; within In 2018, Medicinal Sage (Salvia the scope of the studies we have In accordance with the signed officinalis); Sugar Grass (Stevia); Mor carried out to increase the protocols, planting-planting was Reyhan (Ocimum basilicum); Kudret awareness of the local people carried out in approximately 250 Narı (Momordica charantia); Sprig of Virgin Mary (Silybium marianum); about alternative agricultural decare area. Castor Oil Plant (Ricinus communis) products, protocols were signed Seeds andFennel (Foeniculum with 22 farmers in 17 villages in vulgare) was harvested in the plant. Duzce province in 2017-2018. Medical Plant Breeding
Also planted 6 pieces, Asirantes On the other hand, [Anise; Aspen; Big Bear (Achyranthes bidentata Blume.); Paw; Grass; Çivit Otu; Black seed; Datura; In addition, in the fall of 2018, 20 Rosemary (Rosmarinus officinalis); Widow Avrat Weed; Ekinazy to; Ekinazy to; decares of Izmir (Origanum onites) Red-leaf sweet basil (Ocimum Artichoke; Linen; Red Flowering Thimble; were planted in Bolu province during basilicum L.); Lavender (Lavandula Coriander; Musk Flower; Water clove; the fall in Bolu Forestry Regional Medical Daisy / Bitter Daisy; Hairy Datura; Directorate. Planting-planting is planned intermedia); Misk Island Stream The Hyssop; Anatolian Sage; İzmir Kekiği; for Aynısefa (Calendula officinalis), Boz (Salvia sclarea); Şevketi Bostan Lemon grass; Son otu; Medical Mint; Ot (Marribium parviflorum), Medicinal (Cnicus benedictus) has also been Calendula; Breeding and testing of the Sage (Salvia officinalis) and Golden successful in the plant but has not herbaceous and herbaceous medicinal Weed (Helichrysum aernarium). yet been harvested. plant is also ongoing. Medical Plant Breeding
A harvest festival was held in With the gathering team of a local Hacıyakup village of Düzce province Behind that in our city with rich gathering company, trainings have on 4 September 2018. floristic structure; medicinal-aromatic been given by academicians of our plants such as Elderberry, Ivy, Rosehip, Thank to this harvesting festival, the university. As a result of the trainings Nettle, Ponytail, St. John's Wort, awareness has increased extremity related to the subject, medical Marshmallow, Mallow, Hibiscus, and in 2019, it is aimed to increase aromatic plant gathering will become Dandelion, Nervous Herb are widely the 250 decares of planted-sewn area a serious source of income for the available in nature. to 1000 decares and the decade to local population. 2000 decares. Harvest Festival
• The first Harvest Festival organized within the scope of the specialization activities was realized in Hacıyakup village of Gölyaka district of Düzce.
• In this way, an important awareness has been achieved in general in terms of dissemination of medicinal and aromatic plants.
• Immediately after the harvest festival, feedbacks from the farmers and the entrepreneurs have started to increase to work and invest in this issue. Beekeeping and Bee Products
Within the scope of Bee products (honey, our specialization propolis, pollen, royal works, a contract for jelly, bee venom) production and sale development and of propolis has been dissemination signed with SBS 22 activities are carried beekeepers. out in the region.
In the new season with These activities are Aksuvital, the carried out by the agreement for the Apiculture Research, production of propolis Development and between our Implementation Center beekeepers will be (DAGEM). realized in our control. Medicinal Mushroom Growing
With the studies in this scope, it In 4 villages, 7 farmers were given The production of oyster mushrooms is aimed to evaluate hazelnut training on Oyster Mushroom from the hazelnut green shells was green crusts (hard brown crusts (Pleurotus ostreatus) and 1 carried out successfully in a laboratory environment. which can burn from hazelnuts as farmer in 1 village for cultivation well as green crusts which can of Red Immortal Mushroom In addition, pilot-scale trials were also not be burned) as well as (Ganoderma luciudum) and successful.Laboratory scale trials of Shitake medical fungus have been production of medicinal farmers were encouraged to successful.The reproduction of the mushrooms which are of great produce. micelles of the red reishi mushroom importance in traditional and called immortality mushroom has been complementary medicine area. successfully completed and pilot scale trials with an enterprising peasant continue. Product Development: Basic Studies
Soft honeycomb softjel product studies from mad honey-forest rose honey
Product development studies including nettle, cinnamon and rosehip extract for diabetics
Hb FARMA company for the production of syrup for children, Senegal, Acacia, Rosehip, Carob, Ball oregano and marshmallow plants glliser water mixed extracts production
Investigation of Physicochemical and Phenolic Content, Volatile Compounds and Antimicrobial Properties for Determination of Medical Value of Honey Produced in Düzce
For AKSUVİTAL company Milk thistle ex. (Silymarin [80%]), Artichoke ex. (5% Cynarin), Vitex ex. (2% Vitexin), Grape seed ex. (polyphenols [90%]), Green tea Ex. (polyphenols [50%]), Hawthorn Ex. (2% Vitexins, 2% Hyperosides, 50% Flavonoids), Centranthus (valerenic acid [0.8%]), St. John’s wort ex. (0.3% Hypericins), Calendula ex.(80% Lutein) isolation optimization studies of the active ingredients in the same species plants Product Development: Animal Experiments
• Some product efficacy tests for product development activities at the Animal Experiments Application and Research Center of our University have been completed and still continue in some of them.
Product Development: Product Efficiency Tests Completed in Experimental Animals
The Effects of BOTAFARMA on Reproductive Morphology of Combo Fertilin Product
Investigation of the Effects of the use of Giant fennel (Ferula meifolia) and its Preparations on the Reproduction Morphology of AKSUVİTAL
Studies in this context are carried out under laboratory conditions in cell culture, in preclinical animals in experimental animals or in clinical tests in humans. In this way, traditional medicine is combined with modern medicine. Product Development: Ongoing Product Activity Tests in Experimental Animals
Investigation of Acute Systemic Toxicity of Investigation of Acute Systemic Toxicity of IST-GLIO (Nettle seed, wholemeal, thistle, IST-ARD (Juniper, Nettle Seed, Thistle, ginger, black cumin, turmeric, juniper fruit, Onion, Black Caraway, Ginger, Turmeric) thyme, fennel, anise, cassia and carnation) preparates of NATURIN preparates of NATURIN.
Investigation of Acute Systemic Toxicity of ARD-REM (Juniper Fruit, Overgrowth Investigation of Acute Systemic Toxicity of Seed, Ginger Rhizome Above Ground Part, DVD-ARD (Thistle seed, rosemary, Black Seed, Turmeric Rhizome, Fennel turmeric, juniper fruit, cattle, chicory) Fruit, Anise Fruit, Senna Leaf, Carnation preparates of NATURIN. Flower Seed) preparates of NATURIN.
Investigation of Acute Systemic Toxicity of ARDZ-REM (Juniper fruit, ginger rhizome, Investigation of Acute Systemic Toxicity of overgrowth, oregano aboveground parts, IST-REM (Stinging nettle, thistle, black turmeric rhizome, nigella, ocher, fennel cumin, ginger and turmeric) preparates of fruit, anise fruit, senna leaf, carnation NATURIN. flower bud) preparates of NATURIN. Product Development: Ongoing Product Activity Tests in Experimental Animals
Investigation of Acute Systemic Toxicity of Investigation of Acute Systemic Toxicity of KT-REM (Flax seed, nettle seed, REGULIN (Thistle extract, rosemary overgrowth seed, black seed, ginger extract, turmeric extract, juniper extract, rhizome, turmeric rhizome) preparates of marrow extract and chicory extract) NATURIN. preparates of NATURIN.
Investigation of Acute Systemic Toxicity of ROMX (Juniper extract, ginger extract, hood extract, oregano extract, turmeric Effect of Propolis Extract on Ischemia- extract, black seed extract, fennel extract, Reperfusion Injury; The Role of Estrogen anise extract, senna leaf extract, clove extract) preparates of NATURIN.
The effect of hyperbaric oxygen therapy The Effect of Rhododendron Honey on on metabolic syndrome and insulin Grayanotoxin 3 in Experimental resistance proteins. Hypertension Model. Product Development: Products planned for human clinical trials
For NATURİN company; investigation of therapeutic effect on circulatory system diseases of For Aksuvital company; investigation of the effects ARD-REM (Juniper Fruit, Onion Seed, Ginger of giant fennel (Ferula meifolia) and its preparates Rhizome, Oregano Ground Part, Nigella Seed, on the number and morphology of sperm. Turmeric Rhizome, Fennel Fruit, Anise Fruit, Senna Leaf, Carnation Flower Seed) preparates.
For NATURİN company; investigation of For NATURİN company; investigation of the therapeutic effects against chest diseases of KT- effects of IST-REM (nettle, thistle, coriander, ginger REM (Flaxseed, nettle seed, rye seed, black caraway and turmeric) preparates on sperm quality. seed, ginger rhizome, turmeric rhizome) preparates.
For NATURİN company; investigation of For NATURİN company; investigation of therapeutic effects against chest diseases of therapeutic effects against chest diseases of REGULIN (Thistle extract, rosemary extract, MYGUARD (Thyme, Black Pepper and Ginger) turmeric extract, juniper extract, marrow extract preparates. and chicory extract) preparates. Product Development: Our brand (Boutique production) As Düzce University, product production activities are carried out with our own brand in order to produce model products in traditional and complementary medicine products. The brands to be used are determined by a
competition sponsored by Nobel
Pharmaceuticals. life
DU
life life
DU DU Düzce University Products: Creams
Herbal Cream Containing Nettle
Herbal Cream Herbal Cream Containing Containing Fennel Thyme
Herbal Cream Containing St. John's Wort
Herbal Cream Herbal Cream Containing Containing Lavander Hazelnut Papatya Özlü Bitkisel Krem, Herbal Cream Herbal Cream Containing Containing Esfand Chamomile Düzce University Products: Oils
Esfand Oil
Hazelnut Nettle Oil Oil
Thyme Oil
Lavander St. John's Oil Wort Oil
Fennel Oil Chamomile Oil Düzce University Products: Teas and Colognes
Chamomile Cologne Yellow Centaury Tea (St. John's Tea with Fennel + Wort + Fennel + Passionflower + Hawthorn Repor Ginger + Hibiscus)
Honeysuckle Cologne
Blackberry Cologne Apple Cologne
Licensing works of the products developed by the Ministry of Health are ongoing. In addition, we continue to work on the oil, cream and tea formulations of the new medicinal plants in our city. Applications: Outpatient Services Acupuncture
Hirudotherapy
Cup application
Ozone therapy
Mesotherapy
Phytotherapy
Apitherapy
Music Therapy
Hypnosis For Example… Standards…
Bee…
Direct selling…
Mushroom… Deal with buyers… R&D/Branding
First harvest…
Animal Experiments..
Seedlings from us..
Deal with farmers.. Activities Workshop on Quality and Standardization in Traditional and Complementary Medicine-I
In the first workshop held on 03.05.2018, a road map was prepared to be followed in order to establish standards in all stages of the process from product cultivation to the production and application of the final product. Workshop on Quality and Standardization in Traditional and Complementary Medicine-II
We organized the second one in Istanbul on 19.10.2018. Our aim is to ensure the establishment of standards of international quality in traditional and complementary medicine and to pioneer for this. 5. Specialization in Environment: Recycling of Agricultural Wastes Why Recycling of Agricultural Wastes?
High agricultural potential
Obligation to convert agricultural wastes into value-added products
15 million tons of agricultural waste
Economics based on agriculture and forest products Industrial Waste Recovery
R & D and Pilot Production of Value R & D and Pilot Production of Value Added Chemical Product from Wastes Added Composite Material from Wastes
Eco Paint Insulation Material lignin Parquet Production Tannin Hazelnut Shell Filled Activated Carbon Polymeric Material Fuel Pellet Production Hmf Etc. Program activities
In Düzce around 100 thousand tonnes of Sustainable Material agricultural wastes being Production from in first place hazelnut Agricultural Wastes waste (hard shell and green bark together), come off each year. These Nanocellulose Production wastes are best evaluated only by burning. The conversion of these wastes to value-added Nanolignin Production products is based on. Cooperations
Divapan GP Holding Standard Profil
KAHRAMANMAR AŞ KAĞIT
KMK Paper Fibrobeton FİBRE BETON Sustainable Material Handling from Agricultural Wastes
A protocol was signed with the international GP-AMG company for Within the compost obtained from the production of charcoal, biochar the hazelnut giraffe, after the Organic manure was obtained from and activated carbon from hazelnut successful completion of the trials of the hazelnut giraffe. In addition, the shells. Trial production has started edible mushroom production, the trial studies for the use of hazelnut and the initial investment by the firm pilot scale production in the field shells for weeds were completed. has been started within the was also carried out successfully. boundaries of Gümüşova district of Düzce province. Nanocellulose and Nanolignin Production
Nanocellulose synthesis was With the KMK Paper Factory, a Divapan A.Ş., one of the important achieved by the hazelnut and wheat protocol was signed to improve the industrial enterprises of the region. A husk which is the main agricultural mechanical properties of the paper protocol was signed for the product of the region and whose and a TÜBİTAK 1505 project was reduction of formaldehyde use and a wastes could not be evaluated. adopted for this purpose and a TÜBİTAK 1505 project was Efforts for cooperation with industry project with a budget of 980.000 TL presented for this purpose and is for commercialization activities and was initiated. under evaluation. transformation are ongoing. Nanocellulose and Nanolignin Production
A KOSGEB R & D Innovation With Standard Profile, a Support Program application has protocol was signed to increase A protocol has been signed for the been made with the BALYEMEZ the UV resistance of sealing purpose of examining the use of company, which is on the scale products and a TÜBİTAK 1505 Standard Profiles instead of imported of SME, for the production of materials and a TÜBİTAK 1505 project was presented for this industrial products with the project has been submitted for this purpose and is in the evaluation proliferation of agricultural purpose and is under evaluation. phase. wastes. For Example...
Gümüşova investment…
Technopark: Project proposal
Support in the supply of hazelnut shell and agricultural waste
R&D and consulting from us...
Cooperation with GP AMG Activities 6. Physical Structure The 2500 m2 building, which is used for nuclear medicine activities in the lower floor of the University Hospital, has been designed as a practice and polyclinic area.
A 500 m2 independent block has been allocated within the faculty of Technology within the University for the recycling of agricultural wastes.
8 work package devices were procured for laboratory installation for the use of both centers and 7 work packages were completed.
For the planting and seedling of medicinal plants, a 300 m2 greenhouse cultivation area within the body of the Faculty of Forestry of our University has been allocated and appropriate revision has been started.
50,000 m2 of land was allocated in the village of Köprübaşı Ömer Efendi for trial plantations.
The 50,000 m2 area located in the center of the settlement is planned as a Botanical Garden where plant planting will be made. 7. Projects funded by our University (I)
The Effect of Tranexamic Acid on Fracture Recovery after Closed Reduction and Internal Fixation in 1 Experimentally Generated Long Bone Fractures in Rats 1,891.68 2 The Effect of Nigella Sativa Oil in the Treatment of Early Osteoarthritis in Rabbits 6,002.80 Investigation of Production Possibilities of Lentinus Edoles (Shiitake) Mushroom from Some 3 Lignocellulosic Wastes in Düzce 14,240.80 4 Planting of Herbal Tea and Herbal Cream Using Some Plant Species Growing in Düzce Region 19,593.90 5 R&D Project for new Products with hazelnut 21,090.00 6 Effect of Hyperbaric Oxygen Therapy on Protein-Related Metabolic Syndrome and Insulin Resistance 19,693.64 7 Low Cost Mushroom Rearing Room Design and Production Trials 13,879.87 8 Slymarin Active Ingredient Extraction Process Optimization 18,200.00 9 Investigation of Propolis extracts as a preservative in syrups 18,400.00 10 Investigation of Demand for Musical Therapy in Düzce 17,988.00 11 Investigation of Medicinal and Aromatic Plants of Düzce in the Field of Specialization in Health 997,290.00 12 Medical Plant Extracted Hazelnut Paste Production 13,900.00 13 Synthesis and Application of Silica Based Affinity Columns for Purification of Taxane Molecules 13,900.00 14 Paint Preparation from Hazelnut Shells 13,900.00 The Effects of Shepherd's Pouch (Capsella Bursa-Pastoris) Plant Extract on Gender Hormones in 15 Rats 6,000.00 7. Projects funded by our University (II)
16 EPDM-Based Eco-Friendly Rubber Design 24,223.80 Regional Development Study: International Competitiveness and Meso-Level Clustering 17 296,791.13 Analysis of All Sectors Operating in Duzce Province The Surface Roughness and Wettability of Particleboard Produced from of Hydro 18 2,750.00 Thermally Treated Wheat Stalks Investigation of the effect of Rhododendron Honey on Molecular Changes of Rat Heart 19 27,870.00 Muscles by ATR-Fourier Transformation Infrared (FTIR) Spectroscopy Breeding and Selection of Yığılca Honey Bee Ecotype in terms of Some Behavior, Colony 20 128,723.00 Development and Yield Characteristics The Effect of Tranexamic Acid on Recovery in Osteochondral Lesions Treated with Non- 21 2,879.20 Cellized Matricular Scaffold in Rabbits Determination of AgNOR Protein Levels in Capsaicin Applied Human Prostate Cancer 22 7,500.00 Cell Line (PC3) Investigation of Physicochemical and Phenolic Content, Volatile Compounds and 23 20,975.00 Antimicrobial Properties for Determination of Medical Value of Honey Produced in Düzce Investigation of the Frequency of Application to Traditional and Complementary Medicine 24 25,000.00 Methods in Duzce Province The effect of propolis on gender-related myocardial ischemia-reperfusion injury; The Role 25 48,534.00 of Estrogen The Effect of Epigallocatechin Gallat (EGCG) on Liver Toxicity and Cotinine Levels in 26 13,974.92 Cigarette Smoke Mice TOTAL 1,795,191.74 8. Education and Training Activities
There are 8 PhD students in Natural There are 32 students in the and Cosmetic products in the beekeeping department and 62 in the 100/2000 Program conducted by the medical aromatic plants department. Council of Higher Education.
There are 26 doctoral students in Composite Materials Technology PhD program.
The Council of Higher Education (YÖK) has been made a proposal for the establishment of the Faculty of Pharmacy, which is of vital importance in terms of the existing infrastructure of the University, R&D studies in the field of medicine and the development of herbal, bee products and medicinal fungicides-based health support products. Field Training
• Medicinal and aromatic plant trainings: Medication plant sowing, maintenance, harvest training to all farmers signed contract, • Training of Oyster Mushroom (Pleurotus ostreatus) to 7 farmers in 4 villages and Red Immortality Mushroom (Ganoderma luciudum) training to 1 farmer in 1 village, • Beekeeping and bee resin production trainings in Akçakoca, Yığılca, Cumayeri and Kaynaşlı districts of Düzce province, • Beekeeping and production of royal jelly training for beekeepers in Yığılca district,
And many more training has been given... 9. Intellectual and Industrial Property… Capsaicin Production from Pepper Wastes - Patent Application was realized. Chromatography purification of bakkatin III compound obtained from hazelnut green bark - Patent Application was realized. Chromatography purification of taxane compounds obtained from hazelnut leaves - Patent Application was realized. Protective activity of capsaicin on DNA – Patent Application was realized. Preparation of microcellulose and nanocellulose by Enzymatic Pretreatment from KRAFT Dough - Patent Application was realized. Paper Production from Kraft and Kraft - NABH4 Pastes supported by Micro / Nanocellulose - Patent Application was realized. Use of Ozonated Hazelnut Oil as DNA Protector – Patent Application was realized. Paint production from hazelnut shells – It was decided to make Patent Application in Düzce University Invention Commission. Hazelnut Paste Production with Medical Herbal Extracts – It was decided to make Patent Application in Düzce University Invention Commission. Chromatographic purification process of taxane compounds from hazelnut hard shell - It was decided to make Patent Application in Düzce University Invention Commission. Agricultural, Industrial Waste Additive and Polyurethane Filled Panel - It was decided to make Patent Application in Düzce University Invention Commission. Chromatographic purification process of taxane compounds from hazelnut green bark - It was decided to make Patent Application in Düzce University Invention Commission. 10. Academic Studies (I) Theses The effects of extract of the Shepherd's bag (Capsella bursa-pastoris) on the sex hormones in rats An Ethnobotanical Survey in Çilimli district of Düzce province Investigation of Some Medical Plants Widely Cultivated in Duzce in Terms of Anatomical Properties, Essential Oil Contents and Heavy Metal Accumulation Anatomical, morphological and palynological studies on some Salvia L. (Lamiaceae) taxa distributed around Sakarya province Ethnobotanical Researches in Yigilca (Duzce) Region Skin Absorption of Amanita Phalloides Toxin Alpha Amanitine in Mice Investigation of physicochemical and phenolic content, volatile compounds and antimicrobial properties of honey produced in Düzce Comparison of bee venom content obtained from A.m. anatolliaca and A.m. caucasica honey bees
10. Akademic Studies (II) Theses A study to investigate the production of cream from bee venom Investigation of the Biological Activities of Some Edible Wild Plants The Effect of Using Ozonia, Barrier Cream and Coconut Oil on Dermatitis in Children 0-24 Months The Effect of Milk with Honey, Karadut Syrup on Bleeding, Pain and Wound Healing in Children Undergoing Adenotonsillectomy Evaluation of Efficacy of Aroma Massage (Stinging-Ginger) and Ice Application on Pain in Patients with Knee Osteoarthritis The Effects of Aromatherapy and Hand Massage Applications on Pain and Stress Levels in Arterio-Venous Fistula Cannulation Traditional and Complementary Medicine Applications of Premenstrual Syndrome Women Determination of Resistance of Herbicides of Heifers (Conyza spp.) Ozonation of Non-Refined Hazelnut Oil and Investigation of Physical, Chemical and Biological Activity Determination of extraction conditions of taxa from hazelnut leaf Purification of paclitaxel from hazelnut shell Determination of Extraction Conditions for Paclitaxel in Hazelnut Shell Ozonation of Refined Hazelnut Oil and Investigation of Physical, Chemical and Biological Activity 10. Akademic Studies (III) Publications Altundag Cakir, E., 2017. “A Comprehensive Review on Ethnomedicinal Utilization of Gymnospermae in Turkey”. Eurasian Journal of Forest Science, 5(1): 35-47. Kutlu L., Erim Özdoğan A., Altundağ Çakır E., 2018. Archaeobotanical Studies at Sumaki Hoyuk (Batman, Turkey) in 2014. Eurasian Journal of Forest Science, 6(2): 26-34. A. Bahadir, A. Ceyhan, O. Oz Girgin, B. Yalcın, M. Ulger, T.M. Ozyazgan, A. Yay. ‘‘The protective effects of Curcumin and Beta Carotene on Cisplatin-induced cardiotoxicity: An experimental rat model’’. Anadolu Kardiyoloji Dergisi, 19(3): 213-221, 2018, DOI:10.14744/AnatolJCardiol.2018.53059. İ. YILMAZ, E. KAYA, K. O. YAYKAŞLI, and Y. TÜRKER, “Sıçanlarda intravenöz uygulanan deli bal toksinigrayanotoksin III ün doza bağımlı kardiyak etkileri,” Journal of Dr Behcet Uz Children s Hospital, vol. 7, no. 2, pp. 121–128, Jul. 2017. A. TEKİNSOY, S. ORBAY YASLI, A. SARITAŞ, H. GÜNEŞ, E. KAYA, and F. TURAN SÖNMEZ, “Analysis of Mad Honey Grayanotoksin Cases Admitted to Duzce University School of Medicine Emergency Department,” Open Journal of Emergency Medicine, vol. 5, no. 1, pp. 13–24, Jan. 2017. M. ALPAY, G. DÜLGER, and E. KARABACAK, “Antioxidant Antimicrobial and Antitumoral Effects of Stachys annua L subsp annua var annua in Comperative Cancer Profiles ,” Indian Journal of Medical Research and Pharmaceutical Science, vol. 4, no. 12, pp. 68–74, Dec. 2017. • Our university's specialization studies were shared at the international congress titled “4th International Turkic World Conference on Chemical Sciences and Technologies (ITWCCST 2018)” held in Kyiv, Ukraine. • We represented our country at the conference on Regional Contribution of Universities organized by the Council of Europe in Dublin on 4-5 October 2018. 11. And 2019…
The company's contracts have Renovation of the already reached 22, A total of 1000 building for traditional The cultivation of and we are and complementary decares of trial mushroom from continuing our medicine applications will production will be Beekeeping activities be completed. This hazelnut bark in the efforts to complete completed by will be continued. building will be a full- villages will be 35 contracts this continuing the study fledged practice area with carried out. year. Infrastructure- bedside services and of plant sowing. device purchase laboratories in traditional procedures will be complementary medicine. completed. 11. And 2019…
In order to conduct clinical research in Renewal of the A minimum of 30 Traditional and The blood pressure- Pre-clinical (in-vitro product area allocated Complementary lowering capsule and in-vivo) studies development will be for our Center Medicine production from in Traditional and completed in the for the Recovery applications, andromedotoxine, Complementary product range of application will be which has no of Agricultural Medicine will be medicinal herbal tea, made for a clinical economic value, will Waste Industry continued. oils, creams and trial center license be completed. capsules. will be to the Ministry of completed. Health. 11. And 2019…
Regional income has In the case of Efteni At least 5 more been started to be Investment in Hotel is allocated to Our efforts to R&D projects provided within the the region will our university, it will determine the related to traditional scope of medicinal be our main center standards of every medicine plant cultivation, be made more in the city for our stage of traditional applications will be beekeeping and bee effective in the Traditional Medicine medicine will be initiated. products, medical recovery of applications under continued through At least 10 R&D and mushroom the roof of Health working groups. P&D projects will be cultivation and P&D, agricultural Tourism. launched in 2019. especially in health wastes. tourism revenues. Workshops MELENİS Medical and aromatic plant training workshop VILLAGE: Model Village
Library (Köprü Başı) Product processing workshop
Cosmetics production workshop Training Hall
Showroom and sales area Food production workshop
Medicinal and Agricultural waste aromatic plants Beekeeping and recovery workshop apiculture area sowing area 12. Expected Revenue
Source of Revenue for the Region Amount (TL)
Health Tourism Revenue 90,000,000
Traditional and Complementary Medicine Service 10,000,000 Revenue Medical Product Development Revenue (Medicinal 40,000,000 plant, beekeeping, etc.) Revenue from production of composite material from 75,000,000 agricultural wastes Revenue from chemical waste production from 100,000,000 agricultural wastes Traditional and Complementary Medicine Training 7,000,000 Revenue Other Training Revenue 700,000
TOTAL 322,700,000 13. National and Local Media …