that are preferentially expressed in Type I cells Figure 4A

Rank Moltid 3'ACC Title #Cell_lines Variance PCC 1 GC17295 AA055114 PIK3R1 phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 22 0.023 0.774 2 GC15242 N89600 Homo sapiens cDNA: FLJ22300 fis, clone HRC04759.similar to Rabbit smooth muscle light chain kinase22 0.356 0.773 3 GC17179 AA041360 RIG regulated in glioma, DKK-3 (xenopus dick kopf ortholog) 22 0.086 0.766 4 GC16514 W92322 ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 22 0.04 0.761 5 GC11221 H16240 EST 22 0.049 0.761 6 GC17336 AA056228 ZDHHC7 zinc finger, DHHC domain containing 7 22 0.047 0.759 7 GC9826 AA047403 TPM1 1 (alpha) 22 0.207 0.74 8 GC16967 AA025392 DUSP3 dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) 22 0.046 0.739 9 GC12698 H24785 ESTs 20 0.136 0.735 10 GC12641 R54846 FGFR1 fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) 22 0.178 0.734 11 GC18963 AA040161 SNK serum-inducible kinase 22 0.319 0.732 12 GC15075 N73979 SCHIP1 schwannomin interacting 1 22 0.117 0.732 13 GC17213 AA046749 TPM1 tropomyosin 1 (alpha) 22 0.179 0.723 14 GC14991 N71362 TRIM3 tripartite motif-containing 3 22 0.115 0.72 15 GC14893 N72246 NIT2 Nit protein 2 22 0.029 0.719 16 GC14878 N71998 ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 22 0.226 0.719 17 GC11743 T50788 UGT2B15 UDP 2 family, polypeptide B15 20 0.347 0.713 18 GC18514 AA031453 KIAA0638 KIAA0638 protein 21 0.094 0.707 19 GC14063 N20008 Homo sapiens mRNA; cDNA DKFZp434E235 (from clone DKFZp434E235) 22 0.396 0.698 20 GC10945 R54594 ESTs 18 0.235 0.698 21 GC17207 AA046117 Homo sapiens, clone IMAGE:4798592, mRNA 22 0.06 0.695 22 GC19161 AA044574 CYR61 cysteine-rich, angiogenic inducer, 61 22 0.251 0.695 23 GC10430 AA055792 PTTG1IP pituitary tumor-transforming 1 interacting protein 22 0.047 0.695 24 GC10492 AA057701 GNAS GNAS complex 22 0.079 0.693 25 GC10555 T66144 FGFR1 fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) 22 0.233 0.689 26 GC13411 H95623 22 0.043 0.685 27 GC17874 W90070 TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 22 0.034 0.684 28 GC9849 AA047271 PARVA parvin, alpha 21 0.048 0.678 29 GC17063 AA027324 Homo sapiens cDNA FLJ25134 fis, clone CBR06934. 22 0.034 0.676 30 GC18611 AA034024 RAI14 retinoic acid induced 14 22 0.327 0.675 31 GC11284 H15557 DUSP3 dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) 22 0.048 0.67 32 GC19192 AA043215 LASP1 LIM and SH3 protein 1 22 0.03 0.669 33 GC10514 AA057721 ACTG1 , gamma 1 22 0.025 0.669 34 GC17723 W86749 CerCAM cerebral cell adhesion molecule 21 0.039 0.668 35 GC15402 N95201 Homo sapiens mRNA; cDNA DKFZp586D1122 (from clone DKFZp586D1122) 22 0.064 0.668 36 GC16092 W72904 KIAA0116 KIAA0116 protein 22 0.027 0.664 37 GC11908 T87071 PPP2R3A 2 (formerly 2A), regulatory subunit B'', alpha 20 0.162 0.662 38 GC10609 R17708 NDST1 N-deacetylase/N- (heparan glucosaminyl) 1 22 0.051 0.662 39 GC18188 AA011635 MGC14376 hypothetical protein MGC14376 22 0.154 0.66 40 GC14225 N36415 CDA08 T-cell immunomodulatory protein 22 0.056 0.657 41 GC11926 T85295 Homo sapiens, clone IMAGE:4720228, mRNA 22 0.118 0.653 42 GC11385 H18455 LPAAT-delta lysophosphatidic acid acyltransferase-delta 22 0.085 0.651 43 GC12444 R78226 COL4A1 collagen, type IV, alpha 1 21 0.534 0.651 44 GC18538 AA031696 ENIGMA enigma (LIM domain protein) 22 0.043 0.651 45 GC9736 AA054747 TIP-1 Tax interaction protein 1 22 0.041 0.65 46 GC15013 N69529 BHMT betaine-homocysteine methyltransferase 22 0.076 0.645 47 GC14337 N63451 ESTs, Weakly similar to hypothetical protein FLJ20378 21 0.042 0.645 48 GC17927 AA002153 KIAA1029 synaptopodin 19 0.052 0.643 49 GC17221 AA047566 MYL4 myosin, light polypeptide 4, alkali; atrial, embryonic 22 0.068 0.643 50 GC18554 AA032067 ARHGAP1 Rho GTPase activating protein 1 22 0.024 0.643 51 GC10113 AA054564 COL4A1 collagen, type IV, alpha 1 21 0.259 0.642 52 GC12594 H04238 TNFRSF6 tumor necrosis factor receptor superfamily, member 6 22 0.094 0.641 53 GC10692 R41635 ZDHHC9 zinc finger, DHHC domain containing 9 22 0.046 0.639 54 GC11836 T62074 UGT2B7 UDP glycosyltransferase 2 family, polypeptide B7 20 0.505 0.639 55 GC17494 AA059205 PTPNS1 protein tyrosine phosphatase, non-receptor type substrate 1 22 0.349 0.638 56 GC12383 R68763 Homo sapiens full length insert cDNA YI37C01 22 0.183 0.637 57 GC18241 AA034018 FLJ20507 hypothetical protein FLJ20507 22 0.025 0.637 58 GC11862 T88822 ESTs 20 0.09 0.636 59 GC10308 AA053251 TMEPAI transmembrane, prostate androgen induced RNA 21 0.294 0.636 60 GC15779 W46835 FHL2 four and a half LIM domains 2 22 0.211 0.635 61 GC13123 R99596 22 0.147 0.634 62 GC18321 AA027850 DUSP3 dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) 22 0.045 0.632 63 GC12081 R02281 CSF1 colony stimulating factor 1 () 22 0.219 0.632 64 GC18539 AA031952 ESTs 22 0.034 0.629 65 GC14622 N71935 MPDZ multiple PDZ domain protein 21 0.069 0.629 66 GC9801 AA046642 PRKAG2 , AMP-activated, gamma 2 non-catalytic subunit 22 0.104 0.629 67 GC15789 W49563 Homo sapiens mRNA; cDNA DKFZp434E235 (from clone DKFZp434E235) 21 0.328 0.629 68 GC18798 AA037598 PEA15 phosphoprotein enriched in astrocytes 15 22 0.082 0.628 69 GC15807 W49786 LOC152009 hypothetical protein LOC152009 22 0.136 0.626 70 GC19195 AA043228 CNN3 calponin 3, acidic 22 0.215 0.625 71 GC9761 AA053331 FDPS farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)22 0.234 0.625 72 GC19034 AA044053 DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 22 0.033 0.625 73 GC17062 AA027319 ITM2B integral membrane protein 2B 22 0.031 0.624 74 GC10445 AA057727 ESTs, Highly similar to S03700 nonhistone chromosomal protein HMG-17 - human 21 0.176 0.624 75 GC10815 R43778 APEG1 nuclear protein, marker for differentiated aortic smooth muscle and down-regulated with vascular injury 22 0.161 0.623 76 GC19373 AA045174 Homo sapiens mRNA; cDNA DKFZp586B211 (from clone DKFZp586B211) 22 0.13 0.622 77 GC15996 W73776 PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 22 0.031 0.622 78 GC15822 W52273 HRB2 HIV-1 rev binding protein 2 22 0.118 0.62 79 GC10681 R05666 DP1 likely ortholog of mouse deleted in polyposis 1 22 0.062 0.62 80 GC13072 H52087 22 0.383 0.619 81 GC10682 R05668 SKD3 suppressor of potassium transport defect 3 22 0.045 0.619 82 GC15973 W69170 Homo sapiens cDNA FLJ31668 fis, clone NT2RI2004916. 22 0.22 0.619 83 GC18432 AA029097 LOC146784 hypothetical protein LOC146784 22 0.122 0.619 84 GC19094 AA044414 CALD1 caldesmon 1 22 0.31 0.618 85 GC18422 AA030056 DLC1 deleted in liver cancer 1 22 0.222 0.618 86 GC19310 AA046659 SERPINE1 (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 21 0.313 0.617 87 GC17122 AA040550 AMBP alpha-1-microglobulin/bikunin precursor 21 0.031 0.616 88 GC11882 T90749 ESTs 22 0.193 0.615 89 GC12154 R09550 SDC4 syndecan 4 (amphiglycan, ryudocan) 22 0.071 0.613 90 GC11911 T78450 ESTs 19 0.062 0.612 91 GC12004 T94848 ESTs 22 0.166 0.612 92 GC9970 AA047080 UGCG UDP-glucose ceramide 22 0.137 0.611 93 GC19319 AA046721 FLNA A, alpha (actin binding protein 280) 22 0.155 0.611 94 GC15965 W69630 MYL6 myosin, light polypeptide 6, alkali, smooth muscle and non-muscle 22 0.023 0.611 95 GC11243 H11983 NAV1 neuron navigator 1 22 0.278 0.61 96 GC15506 N94578 NIT2 Nit protein 2 22 0.354 0.61 97 GC14414 N46354 GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 18 0.081 0.61 98 GC14474 N47107 NEK6 NIMA (never in mitosis gene a)-related kinase 6 22 0.101 0.609 99 GC11386 H18456 ESTs 22 0.368 0.608 100 GC11896 T91987 ESTs 21 0.066 0.608 101 GC18506 AA031968 VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 22 0.094 0.607 102 GC11263 H14977 21 0.843 0.607 103 GC9719 AA045751 UBE2A ubiquitin-conjugating E2A (RAD6 homolog) 22 0.035 0.607 104 GC15795 W49494 KIAA0375 KIAA0375 gene product 21 0.072 0.607 105 GC16470 W96206 EXT1 exostoses (multiple) 1 22 0.027 0.606 106 GC12221 R22919 EST-YD1 EST-YD1 protein 22 0.049 0.606 107 GC14298 N34396 Homo sapiens cDNA FLJ13034 fis, clone NT2RP3001232. 22 0.085 0.606 108 GC12495 R81328 ESTs 22 0.034 0.604 109 GC18130 AA007361 PP1628 hypothetical protein PP1628 22 0.166 0.604 110 GC14075 N20199 MGC3178 thioredoxin related protein 22 0.093 0.602 111 GC12856 H50100 C14orf34 14 open reading frame 34 22 0.067 0.599 112 GC9774 AA058703 Homo sapiens cDNA FLJ30550 fis, clone BRAWH2001502. 22 0.346 0.598 113 GC14889 N67688 ESTs, Weakly similar to hypothetical protein FLJ20378 22 0.143 0.598 114 GC18235 AA033790 APOD apolipoprotein D 22 0.117 0.597 115 GC15251 N79566 PRICKLE2 prickle-like 2 (Drosophila) 21 0.193 0.597 116 GC17183 AA041260 FLJ20297 hypothetical protein FLJ20297 22 0.021 0.596 117 GC18479 AA031657 LOC51159 colon carcinoma related protein 22 0.181 0.596 118 GC15808 W48562 PTX3 pentaxin-related gene, rapidly induced by IL-1 beta 19 0.083 0.594 119 GC14720 N62311 MYOZ3 myozenin 3 22 0.021 0.594 120 GC17803 W88807 Homo sapiens cDNA FLJ34757 fis, clone NT2NE2001725. 22 0.143 0.594 121 GC10102 AA054510 NRIP1 interacting protein 1 21 0.224 0.592 122 GC18423 AA030058 HSOBRGRP leptin receptor gene-related protein 22 0.113 0.592 123 GC16862 AA024819 PTPRF protein tyrosine phosphatase, receptor type, F 22 0.056 0.592 124 GC11900 T91043 AXL AXL receptor tyrosine kinase 22 0.162 0.59 125 GC18869 AA039340 ANXA4 annexin A4 22 0.143 0.59 126 GC14599 N64806 Homo sapiens mRNA; cDNA DKFZp761M0223 (from clone DKFZp761M0223) 22 0.085 0.59 127 GC18481 AA031660 FLJ36090 hypothetical protein FLJ36090 22 0.105 0.589 128 GC16099 W72569 NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 22 0.343 0.589 129 GC12214 R21832 MGC20235 hypothetical protein MGC20235 22 0.428 0.589 130 GC18588 AA033633 P164RHOGEF Rho-specific guanine-nucleotide exchange factor 164 kDa 22 0.063 0.589 131 GC12540 H01822 ESTs 20 0.132 0.589 132 GC17780 W90037 DUSP1 dual specificity phosphatase 1 22 0.174 0.589 133 GC17799 W88650 RCL putative c-Myc-responsive 22 0.167 0.589 134 GC9846 AA044804 ESTs, Highly similar to hypothetical protein FLJ10350 22 0.031 0.588 135 GC12634 R53619 FLJ21079 hypothetical protein FLJ21079 22 0.239 0.588 136 GC15826 W52295 FGF2 fibroblast growth factor 2 (basic) 22 0.349 0.586 137 GC9724 AA054721 ZYX zyxin 22 0.058 0.586 138 GC11891 T91121 APOB apolipoprotein B (including Ag(x) antigen) 20 0.033 0.585 139 GC15201 N78799 NAV1 neuron navigator 1 22 0.143 0.583 140 GC19072 AA044261 ESTs, Highly similar to ITB1_HUMAN Integrin beta-1 precursor (Fibronectin receptor beta subunit) (CD29) (Integrin22 VLA-40.161 beta subunit)0.582 141 GC14187 N34799 FLJ23306 hypothetical protein FLJ23306 22 0.138 0.582 142 GC12487 H01302 RPS4X ribosomal protein S4, X-linked 22 0.062 0.582 143 GC13200 H61552 C3orf6 open reading frame 6 22 0.022 0.581 144 GC14968 N69299 HPS3 Hermansky-Pudlak syndrome 3 22 0.032 0.58 145 GC15256 N90929 ESTs 22 0.045 0.579 146 GC18472 AA031646 NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa 22 0.184 0.578 147 GC13333 H77597 MT1H metallothionein 1H 22 0.127 0.578 148 GC16103 W72468 FAM13A1 family with sequence similarity 13, member A1 22 0.323 0.578 149 GC18691 AA035398 ALEX2 armadillo repeat protein ALEX2 20 0.403 0.577 150 GC17562 W80373 21 0.089 0.577 151 GC16854 AA024510 DFNA5 deafness, autosomal dominant 5 22 0.08 0.576 152 GC11013 R60766 GNA12 guanine nucleotide binding protein () alpha 12 22 0.027 0.576 153 GC18878 AA039584 NAV3 neuron navigator 3 21 0.163 0.576 154 GC14433 N48319 BCAR3 breast cancer anti-estrogen resistance 3 22 0.191 0.575 155 GC13345 H74077 ITM2B integral membrane protein 2B 22 0.034 0.575 156 GC17333 AA056022 CSPG2 2 (versican) 22 0.516 0.575 157 GC18452 AA031314 PGRMC2 progesterone receptor membrane component 2 22 0.031 0.575 158 GC10581 R39221 MAPK10 mitogen-activated protein kinase 10 21 0.074 0.572 159 GC15059 N74406 BRP44L brain protein 44-like 22 0.035 0.572 160 GC18469 AA031651 LPIN2 lipin 2 22 0.084 0.572 161 GC9783 AA046420 CGI-48 CGI-48 protein 22 0.025 0.571 162 GC11515 H29581 STMN4 -like 4 22 0.235 0.569 163 GC11382 H17912 SPAG9 sperm associated antigen 9 22 0.03 0.569 164 GC16215 W79783 PACSIN2 protein kinase C and casein kinase substrate in neurons 2 22 0.034 0.569 165 GC13305 H69879 ESTs 19 0.124 0.568 166 GC16530 AA009987 COL18A1 collagen, type XVIII, alpha 1 21 0.128 0.568 167 GC18770 AA057170 ADAMTS1 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1 21 0.272 0.568 168 GC13353 H84205 EST 22 0.039 0.568 169 GC17493 AA059198 FLJ10652 hypothetical protein FLJ10652 21 0.16 0.568 170 GC12522 H01502 HFE hemochromatosis 22 0.047 0.567 171 GC12431 R76888 GLIPR1 GLI pathogenesis-related 1 (glioma) 22 0.163 0.567 172 GC14091 N21401 HSOBRGRP leptin receptor gene-related protein 22 0.073 0.566 173 GC11875 T90222 Homo sapiens cDNA FLJ12220 fis, clone MAMMA1001082. 18 0.169 0.566 174 GC18343 AA028007 FBXL2 F-box and leucine-rich repeat protein 2 22 0.06 0.564 175 GC16111 W73890 Homo sapiens cDNA FLJ39389 fis, clone PLACE6003621. 21 0.189 0.563 176 GC13958 N26836 SLC22A4 solute carrier family 22 (organic cation transporter), member 4 22 0.104 0.563 177 GC18600 AA033582 DOC1 downregulated in ovarian cancer 1 21 0.063 0.562 178 GC10914 R51727 ESTs, Weakly similar to hypothetical protein FLJ20378 22 0.038 0.561 179 GC14152 N27159 INHBA inhibin, beta A (activin A, activin AB alpha polypeptide) 20 0.156 0.56 180 GC14366 N66121 FLJ22167 hypothetical protein FLJ22167 22 0.103 0.56 181 GC12215 R21877 FLJ20727 hypothetical protein FLJ20727 21 0.364 0.56 182 GC18723 AA035186 Homo sapiens mRNA; cDNA DKFZp686M1629 (from clone DKFZp686M1629) 22 0.036 0.559 183 GC15238 N78771 HMGCS2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) 22 0.025 0.559 184 GC12535 H00657 ESTs 22 0.112 0.557 185 GC18107 AA004839 NNMT nicotinamide N-methyltransferase 22 0.606 0.557 186 GC11277 H16591 VCAM1 vascular cell adhesion molecule 1 21 0.668 0.556 187 GC17298 AA055243 FAD104 FAD104 22 0.077 0.555 188 GC17696 W86506 22 0.072 0.555 189 GC19158 AA044277 Homo sapiens cDNA FLJ90031 fis, clone HEMBA1001390, weakly similar to Mus musculus polymerase I-transcript22 release0.097 factor mRNA.0.554 190 GC18477 AA031595 AMPD3 adenosine monophosphate deaminase (isoform E) 22 0.331 0.554 191 GC14079 N20213 MAP1B -associated protein 1B 22 0.317 0.554 192 GC16836 AA025310 THBS3 thrombospondin 3 22 0.125 0.553 193 GC12126 R08017 JUN v-jun sarcoma virus 17 oncogene homolog (avian) 20 0.067 0.553 194 GC19312 AA046660 EST 22 0.138 0.553 195 GC14210 N35886 JUB jub, ajuba homolog (Xenopus laevis) 22 0.133 0.552 196 GC17417 AA057431 TRPM1 transient receptor potential cation channel, subfamily M, member 1 22 0.028 0.552 197 GC16606 AA013396 ESTs 22 0.116 0.552 198 GC17005 AA026608 ACTA1 actin, alpha 1, 22 0.02 0.551 199 GC17411 AA054630 TLE1 -like enhancer of split 1 (E(sp1) homolog, Drosophila) 22 0.024 0.551 200 GC18391 AA029224 PICALM phosphatidylinositol binding clathrin assembly protein 22 0.023 0.55