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THAI MALENA A US009976180B2HA UNA ALTA KAMA NINA MITTE (12 ) United States Patent (10 ) Patent No. : US 9 , 976 , 180 B2 Hatchwell et al. (45 ) Date of Patent: May 22 , 2018 ( 54 ) METHODS FOR DETECTING A GENETIC 5 ,665 , 549 A 9 / 1997 Pinkel et al . 5 , 700 ,637 A 12 / 1997 Southern VARIATION IN SUBJECTS WITH 5 , 744 ,305 A 4 / 1998 Fodor et al . PARKINSONISM 5 ,776 ,434 A 7 / 1998 Purewal et al . 5 ,811 , 128 A 9 / 1998 Tice et al . (71 ) Applicant: Population Bio , Inc ., Melville , NY 5 , 814 ,344 A 9 / 1998 Tice et al . (US ) 5 ,820 , 883 A 10 / 1998 Tice et al . 5 ,837 , 832 A 11/ 1998 Chee et al. 5 ,853 , 763 A 12 / 1998 Tice et al. ( 72 ) Inventors : Eli Hatchwell , Winchester (GB ); Peggy 5 , 858 ,659 A 1 / 1999 Sapolsky et al. S . Eis , Fitchburg , WI (US ) 5 , 928 ,647 A 7 / 1999 Rock 5 , 942 ,252 A 8 / 1999 Tice et al. ( 73 ) Assignee: POPULATION BIO , INC ., Melville , 5 , 945 , 334 A 8 / 1999 Besemer et al . 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