Representation of Such Veterans in the Examination Sample Was Not Very Different Rom That in the Interview Sample (Table 3.15)
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Chloracne: from Clinic to Research
DERMATOLOGICA SINICA 30 (2012) 2e6 Contents lists available at SciVerse ScienceDirect Dermatologica Sinica journal homepage: http://www.derm-sinica.com REVIEW ARTICLE Chloracne: From clinic to research Qiang Ju 1, Kuochia Yang 2, Christos C. Zouboulis 3, Johannes Ring 4, Wenchieh Chen 4,* 1 Department of Dermatology, Shanghai Skin Disease and STD Hospital, Shanghai, People’s Republic of China 2 Department of Dermatology, Changhua Christian Hospital, Changhua, Taiwan 3 Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Dessau, Germany 4 Department of Dermatology and Allergy, Technische Universität München, Munich, Germany article info abstract Article history: Chloracne is the most sensitive and specific marker for a possible dioxin (2,3,7,8-tetrachlorodibenzo-p- Received: Oct 31, 2011 dioxin) intoxication. It is clinically characterized by multiple acneiform comedone-like cystic eruptions Revised: Nov 9, 2011 mainly involving face in the malar, temporal, mandibular, auricular/retroauricular regions, and the Accepted: Nov 9, 2011 genitalia, often occurring in age groups not typical for acne vulgaris. Histopathology is essential for adefinite diagnosis, which exhibits atrophy or absence of sebaceous glands as well as infundibular Keywords: dilatation or cystic formation of hair follicles, hyperplasia of epidermis, and hyperpigmentation of aryl hydrocarbon receptor stratum corneum. The appearance of chloracne and its clinical severity does not correlate with the blood chloracne “ ” 2,3,7,8-tetrachlorodibenzo-p-dioxin levels of dioxins. Pathogenesis of chloracne remains largely unclear. An aryl hydrocarbon receptor - polyhalogenated aromatic hydrocarbons mediated signaling pathway affecting the multipotent stem cells in the pilosebaceous units is probably sebaceous gland the major molecular mechanism inducing chloracne. -
Compensation for Occupational Skin Diseases
ORIGINAL ARTICLE http://dx.doi.org/10.3346/jkms.2014.29.S.S52 • J Korean Med Sci 2014; 29: S52-58 Compensation for Occupational Skin Diseases Han-Soo Song1 and Hyun-chul Ryou2 The Korean list of occupational skin diseases was amended in July 2013. The past list was constructed according to the causative agent and the target organ, and the items of that 1 Department of Occupational and Environmental list had not been reviewed for a long period. The revised list was reconstructed to include Medicine, College of Medicine, Chosun University, Gwangju; 2Teo Center of Occupational and diseases classified by the International Classification of Diseases (10th version). Therefore, Environmental Medicine, Changwon, Korea the items of compensable occupational skin diseases in the amended list in Korea comprise contact dermatitis; chemical burns; Stevens-Johnson syndrome; tar-related skin diseases; Received: 19 December 2013 infectious skin diseases; skin injury-induced cellulitis; and skin conditions resulting from Accepted: 2 May 2014 physical factors such as heat, cold, sun exposure, and ionized radiation. This list will be Address for Correspondence: more practical and convenient for physicians and workers because it follows a disease- Han-Soo Song, MD based approach. The revised list is in accordance with the International Labor Organization Department of Occupational and Environmental Medicine, Chosun University Hospital, 365 Pilmun-daero, Dong-gu, list and is refined according to Korean worker’s compensation and the actual occurrence of Gwangju 501-717, Korea occupational skin diseases. However, this revised list does not perfectly reflect the actual Tel: +82.62-220-3689, Fax: +82.62-443-5035 E-mail: [email protected] status of skin diseases because of the few cases of occupational skin diseases, incomplete statistics of skin diseases, and insufficient scientific evidence. -
General Dermatology an Atlas of Diagnosis and Management 2007
An Atlas of Diagnosis and Management GENERAL DERMATOLOGY John SC English, FRCP Department of Dermatology Queen's Medical Centre Nottingham University Hospitals NHS Trust Nottingham, UK CLINICAL PUBLISHING OXFORD Clinical Publishing An imprint of Atlas Medical Publishing Ltd Oxford Centre for Innovation Mill Street, Oxford OX2 0JX, UK tel: +44 1865 811116 fax: +44 1865 251550 email: [email protected] web: www.clinicalpublishing.co.uk Distributed in USA and Canada by: Clinical Publishing 30 Amberwood Parkway Ashland OH 44805 USA tel: 800-247-6553 (toll free within US and Canada) fax: 419-281-6883 email: [email protected] Distributed in UK and Rest of World by: Marston Book Services Ltd PO Box 269 Abingdon Oxon OX14 4YN UK tel: +44 1235 465500 fax: +44 1235 465555 email: [email protected] © Atlas Medical Publishing Ltd 2007 First published 2007 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, without the prior permission in writing of Clinical Publishing or Atlas Medical Publishing Ltd. Although every effort has been made to ensure that all owners of copyright material have been acknowledged in this publication, we would be glad to acknowledge in subsequent reprints or editions any omissions brought to our attention. A catalogue record of this book is available from the British Library ISBN-13 978 1 904392 76 7 Electronic ISBN 978 1 84692 568 9 The publisher makes no representation, express or implied, that the dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up-to-date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. -
Mask-Induced Acne Flare During Coronavirus Disease-19. What Is It and How to Manage It?
Scientific Foundation SPIROSKI, Skopje, Republic of Macedonia Open Access Macedonian Journal of Medical Sciences. 2020 Oct 31; 8(T1):411-415. https://doi.org/10.3889/oamjms.2020.5388 eISSN: 1857-9655 Category: T1 - Thematic Issue “Coronavirus Disease (COVID-19)” Section: Narrative Review Article MASKNE: Mask-Induced Acne Flare During Coronavirus Disease-19. What is it and How to Manage it? Laura Pauline Kosasih Department of Dermatology, Cardiff University, Cardiff, Wales, United Kingdom Abstract Edited by: Mirko Spiroski The coronavirus disease (COVID)-19 is a global pandemic caused by severe acute respiratory syndrome (SARS)- Citation: Kosasih LP. MASKNE: Mask Induced Acne Flare During Coronavirus Disease-19. What is it and How to CoV-2. Due to the rapid spread of the disease, several measures have been proposed to mitigate its transmission, Manage it? Open Access Maced J Med Sci. 2020 Oct 31; including wearing a mask in certain circumstances. This new proposition leads to some novel skin adverse effects; 8(T1):411-415. one of them is acne flare. This particular outbreak has significantly affected people’s quality of life. In this minireview, https://doi.org/10.3889/oamjms.2020.5388 Keywords: Acne; MASKNE (Mask Acne); a brief current knowledge of SARS-CoV-2 and its related-acne-flare, or popularly called as mask-acne (MASKNE), Coronavirus Disease-19 are discussed. This review aims to provide some information that may be helpful in opting for the most suitable *Correspondence: Laura Pauline Kosasih, Department of Dermatology, Cardiff -
Canadian Clinical Practice Guideline on the Management of Acne (Full Guideline)
Appendix 4 (as supplied by the authors): Canadian Clinical Practice Guideline on the Management of Acne (full guideline) Asai, Y 1, Baibergenova A 2, Dutil M 3, Humphrey S 4, Hull P 5, Lynde C 6, Poulin Y 7, Shear N 8, Tan J 9, Toole J 10, Zip C 11 1. Assistant Professor, Queens University, Kingston, Ontario 2. Private practice, Markham, Ontario 3. Assistant Professor, University of Toronto, Toronto, Ontario 4. Clinical Assistant Professor, University of British Columbia, Vancouver, British Columbia 5. Professor, Dalhousie University, Halifax, Nova Scotia 6. Associate Professor, University of Toronto, Toronto, Ontario 7. Associate Clinical Professor, Laval University, Laval, Quebec 8. Professor, University of Toronto, Toronto, Ontario 9. Adjunct Professor, University of Western Ontario, Windsor, Ontario 10. Professor, University of Manitoba, Winnipeg, Manitoba 11. Clinical Associate Professor, University of Calgary, Calgary, Alberta Appendix to: Asai Y, Baibergenova A, Dutil M, et al. Management of acne: Canadian clinical practice guideline. CMAJ 2015. DOI:10.1503/cmaj.140665. Copyright © 2016 The Author(s) or their employer(s). To receive this resource in an accessible format, please contact us at [email protected]. Contents List of Tables and Figures ............................................................................................................. v I. Introduction ................................................................................................................................ 1 I.1 Is a Clinical Practice Guideline -
International Journal of Scientific Research
ORIGINAL RESEARCH PAPER Volume-9 | Issue-1 | January-2020 | PRINT ISSN No. 2277 - 8179 | DOI : 10.36106/ijsr INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH TYPES AND VARIANTS OF ACNE Dermatology Shailee Patel ABSTRACT Acne occur when pores of skin are blocked with oil, dead skin, or bacteria. It can occur when excessive oil is produced by follicles, bacteria build up in pores, and dead skin cells accumulate in pores. All these problem contribute in development of pimple. Acne are majorly seen among teenagers but they can also occur in adults. There are varying from of acne, and their varying treatment. KEYWORDS 1.INTRODUCTION ulcerative colitis and Crohn's disease and syndromes, such as Acne is linked to the change in hormone level during puberty. Acne is a synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) and disorder that is seen worldwide. Acne is a disease of the teenagers but pyogenic arthritis, pyoderma gangrenosum, and acne (PAPA) can be seen even in newborn children and also adults. Age and gender syndromes. also play a very important role in onset of acne. Acne most commonly occur between the ages of 10-13 years. Girls have an earlier onset 3.4 Occupational Acne which easily contribute to the onset of puberty in girls than in boys. The Occupational acne is defined as development of acne-like lesions after disease severity in more in boys during the late adolescence. Acne exposure to occupational agents in persons not prone to develop acne mostly develops on areas of skin that have abundant oil glands, like the and who have not had acne before engaging in the said occupation. -
Acne Vulgaris
Seminar Acne vulgaris Hywel C Williams, Robert P Dellavalle, Sarah Garner Acne is a chronic infl ammatory disease of the pilosebaceous unit resulting from androgen-induced increased sebum Lancet 2012; 379: 361–72 production, altered keratinisation, infl ammation, and bacterial colonisation of hair follicles on the face, neck, chest, Published Online and back by Propionibacterium acnes. Although early colonisation with P acnes and family history might have important August 30, 2011 roles in the disease, exactly what triggers acne and how treatment aff ects the course of the disease remain unclear. DOI:10.1016/S0140- 6736(11)60321-8 Other factors such as diet have been implicated, but not proven. Facial scarring due to acne aff ects up to 20% of This publication has teenagers. Acne can persist into adulthood, with detrimental eff ects on self-esteem. There is no ideal treatment for been corrected. acne, although a suitable regimen for reducing lesions can be found for most patients. Good quality evidence on The corrected version fi rst comparative eff ectiveness of common topical and systemic acne therapies is scarce. Topical therapies including appeared at thelancet.com benzoyl peroxide, retinoids, and antibiotics when used in combination usually improve control of mild to moderate on January 27, 2011 acne. Treatment with combined oral contraceptives can help women with acne. Patients with more severe infl ammatory Centre of Evidence-Based Dermatology, Nottingham acne usually need oral antibiotics combined with topical benzoyl peroxide to decrease antibiotic-resistant organisms. University Hospitals NHS Oral isotretinoin is the most eff ective therapy and is used early in severe disease, although its use is limited by Trust, Nottingham, UK teratogenicity and other side-eff ects. -
Occupational Skin Disease C.J
Postgraduate Medical Journal (1989) 65, 374- 380 Postgrad Med J: first published as 10.1136/pgmj.65.764.374 on 1 June 1989. Downloaded from Occupational Medicine Occupational skin disease C.J. Stevenson Department ofOccupational Health and Hygiene, University ofNewcastle upon Tyne, Newcastle upon Tyne, UK. Introduction Diagnosis ofoccupational skin disease It is opportune to discuss occupational skin disorders Early diagnosis depends upon awareness of the pos- since recently a 'Save your Skin' Campaign has been sibility that a presenting dermatosis can be occupa- undertaken in the United Kingdom by the Employ- tional in origin. Sometimes the dermatosis is quite ment Advisory Service of the Health and Safety specific for exposure to a chemical, for example the Executive to increase the awareness of employers and lichenoid dermatosis seen in persons working with employees of the need to prevent skin problems in colour developers.3 Sometimes the dermatosis is a industry.' This was justified because skin disorders lookalike of a non-occupational disorder, such as caused by substances at work are the most common vitiligo, and sometimes we are faced with contact occupational health problem. dermatitis which could equally well be due to an Contact dermatitis (eczematous dermatitis of offending substance in the domestic environment. It is predominantly exogenous aetiology) is the com- important to realise that the environment is constantly monest form of occupational skin disease. However, changing and new processes are being introduced. For other occupational skin disorders occur, often presen- example, grass cutting by strimmers is now known to ting to physicians of different disciplines, for example cause a distinctive phytophotodermatosis in some infectious conditions, occupational skin cancer, individuals.4 copyright. -
Acne and Related Conditions
Rosanne Paul, DO Madeline Tarrillion, DO Miesha Merati, DO Gregory Delost, DO Emily Shelley, DO Jenifer R. Lloyd, DO, FAAD American Osteopathic College of Dermatology Disclosures • We do not have any relevant disclosures. Cleveland before June 2016 Cleveland after June 2016 Overview • Acne Vulgaris • Folliculitis & other – Pathogenesis follicular disorders – Clinical Features • Variants – Treatments • Rosacea – Pathogenesis – Classification & clinical features • Rosacea-like disorders – Treatment Acne vulgaris • Pathogenesis • Multifactorial • Genetics – role remains uncertain • Sebum – hormonal stimulation • Comedo • Inflammatory response • Propionibacterium acnes • Hormonal influences • Diet Bolognia et al. Dermatology. 2012. Acne vulgaris • Clinical Features • Face & upper trunk • Non-inflammatory lesions • Open & closed comedones • Inflammatory lesions • Pustules, nodules & cysts • Post-inflammatory hyperpigmentation • Scarring • Pitted or hypertrophic Bolognia et al. Dermatology. 2012. Bolognia et al. Dermatology. 2012. Acne variants • Acne fulminans • Acne conglobata • PAPA syndrome • Solid facial edema • Acne mechanica • Acne excoriée • Drug-induced Bolognia et al. Dermatology. 2012. Bolognia et al. Dermatology. 2012. Bolognia et al. Dermatology. 2012. Bolognia et al. Dermatology. 2012. Acne variants • Occupational • Chloracne • Neonatal acne (neonatal cephalic pustulosis) • Infantile acne • Endocrinological abnormalities • Apert syndrome Bolognia et al. Dermatology. 2012. Bolognia et al. Dermatology. 2012. Acne variants • Acneiform -
(12) United States Patent (10) Patent No.: US 7,359,748 B1 Drugge (45) Date of Patent: Apr
USOO7359748B1 (12) United States Patent (10) Patent No.: US 7,359,748 B1 Drugge (45) Date of Patent: Apr. 15, 2008 (54) APPARATUS FOR TOTAL IMMERSION 6,339,216 B1* 1/2002 Wake ..................... 250,214. A PHOTOGRAPHY 6,397,091 B2 * 5/2002 Diab et al. .................. 600,323 6,556,858 B1 * 4/2003 Zeman ............. ... 600,473 (76) Inventor: Rhett Drugge, 50 Glenbrook Rd., Suite 6,597,941 B2. T/2003 Fontenot et al. ............ 600/473 1C, Stamford, NH (US) 06902-2914 7,092,014 B1 8/2006 Li et al. .................. 348.218.1 (*) Notice: Subject to any disclaimer, the term of this k cited. by examiner patent is extended or adjusted under 35 Primary Examiner Daniel Robinson U.S.C. 154(b) by 802 days. (74) Attorney, Agent, or Firm—McCarter & English, LLP (21) Appl. No.: 09/625,712 (57) ABSTRACT (22) Filed: Jul. 26, 2000 Total Immersion Photography (TIP) is disclosed, preferably for the use of screening for various medical and cosmetic (51) Int. Cl. conditions. TIP, in a preferred embodiment, comprises an A6 IB 6/00 (2006.01) enclosed structure that may be sized in accordance with an (52) U.S. Cl. ....................................... 600/476; 600/477 entire person, or individual body parts. Disposed therein are (58) Field of Classification Search ................ 600/476, a plurality of imaging means which may gather a variety of 600/162,407, 477, 478,479, 480; A61 B 6/00 information, e.g., chemical, light, temperature, etc. In a See application file for complete search history. preferred embodiment, a computer and plurality of USB (56) References Cited hubs are used to remotely operate and control digital cam eras. -
Epidemiology of Acne Vulgaris (Excluding Acne Rosacea, Infantile Acne, Acne Inversa)
K. Bhate Centre of Evidence Based Dermatology University of Nottingham Overview Background Objectives and Method Findings Incidence Natural history Morbidity Socioeconomic impact Overview - 2 Genetics Ethnicity Diet Sunlight Hygiene Smoking Obesity Stress Infection One or two others.. Conclusion Background Epidemiology Incidence Prevalence Age, sex, social class Ethnic group and geography Natural history Risk factors for disease occurrence or progression Why is it important? Objective To provide a comprehensive review on the Epidemiology of Acne vulgaris (excluding acne rosacea, infantile acne, acne inversa) Baseline for future work Provocation trial Cohort study Methods Medline database (in process and other non-indexed citations 1946-present) Embase 1974 to the end of January 2012 NHS Evidence Acne vulgaris with epidemiology, aetiology, cause, prevalence, incidence, cost, pharmacoeconomics, socioeconomic, natural history, race, ethnicity, morbidity, quality of life, geography, family size, severity, excoriation, obesity, overweight, pathogenesis, washing, sweat, cleanse, sun, sunlight, light, diet, dairy, milk, GI, high GI, glycaemic/glycemic index, chocolate, hygiene, smoking, prevention, climate, environment, obesity, infection, Propionibacterium acnes (P. acnes), stress, picking, chloracne, drugs and medicine. Truncation to expand upon suffices No use of additional limits No pre-specified criteria for study exclusion or inclusion Results and Outcome Measures 173 papers included! Outcome measures How common is acne? All people between 15 and 17 15-20% classified as moderate to severe Prevalence data and 1996 census data - prevalence rate in 12-24 year olds 50% of 10 and 11 year old have more than 10 comedones and almost 80% of 8.5-12.2 year old had a degree of acne How long does acne last? Pre-pubertal children tend to have non-inflammatory acne – no sebum therefore no P. -
Chloracne and Hyperpigmentation Caused by Exposure to Hazardous Aryl Hydrocarbon Receptor Ligands
International Journal of Environmental Research and Public Health Review Chloracne and Hyperpigmentation Caused by Exposure to Hazardous Aryl Hydrocarbon Receptor Ligands Masutaka Furue 1,2,3,* and Gaku Tsuji 1,2 1 Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashiku, Fukuoka 812-8582, Japan; [email protected] 2 Research and Clinical Center for Yusho and Dioxin, Kyushu University, Maidashi 3-1-1, Higashiku, Fukuoka 812-8582, Japan 3 Division of Skin Surface Sensing, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashiku, Fukuoka 812-8582, Japan * Correspondence: [email protected]; Tel.: +81-92-642-5581; Fax: +81-92-642-5600 Received: 21 October 2019; Accepted: 2 December 2019; Published: 3 December 2019 Abstract: Dioxins and dioxin-like compounds are environmental pollutants that are hazardous to human skin. They can be present in contaminated soil, water, and air particles (such as ambient PM2.5). Exposure to a high concentration of dioxins induces chloracne and hyperpigmentation. These chemicals exert their toxic effects by activating the aryl hydrocarbon receptor (AHR) which is abundantly expressed in skin cells, such as keratinocytes, sebocytes, and melanocytes. Ligation of AHR by dioxins induces exaggerated acceleration of epidermal terminal differentiation (keratinization) and converts sebocytes toward keratinocyte differentiation, which results in chloracne formation. AHR activation potently upregulates melanogenesis in melanocytes by upregulating the expression of melanogenic enzymes, which results in hyperpigmentation. Because AHR-mediated oxidative stress contributes to these hazardous effects, antioxidative agents may be potentially therapeutic for chloracne and hyperpigmentation.