SLAMF6 Rabbit Pab

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Leader in Biomolecular Solutions for Life Science SLAMF6 Rabbit pAb Catalog No.: A10338 Basic Information Background Catalog No. The protein encoded by this gene is a type I transmembrane protein, belonging to the A10338 CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and Observed MW associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with 70kDa SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked Calculated MW lymphoproliferative patients. Alternative splicing results in multiple transcript variants 24kDa/37kDa encoding distinct isoforms. Category Primary antibody Applications WB Cross-Reactivity Human, Mouse, Rat Recommended Dilutions Immunogen Information WB 1:500 - 1:2000 Gene ID Swiss Prot 114836 Q96DU3 Immunogen Recombinant protein of human SLAMF6 Synonyms SLAMF6;CD352;KALI;KALIb;Ly108;NTB-A;NTBA;SF2000 Contact Product Information www.abclonal.com Source Isotype Purification Rabbit IgG Affinity purification Storage Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. Validation Data Western blot analysis of extracts of Jurkat cells, using SLAMF6 antibody (A10338) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. Western blot analysis of extracts of various cell lines, using SLAMF6 antibody (A10338) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 10s. Antibody | Protein | ELISA Kits | Enzyme | NGS | Service For research use only. Not for therapeutic or diagnostic purposes. Please visit http://abclonal.com for a complete listing of recommended products..

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Restimulation-Induced Apoptosis of T Cells Is Impaired in Patients with X-Linked Lymphoproliferative Disease Caused by SAP Deficiency
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