Nfap Policy Brief » October 2020
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Donna Strickland '89 (Phd), a Self-Described “Laser Jock,” Receives
Donna Strickland ’89 (PhD), a self-described “laser jock,” receives the Nobel Prize, along with her advisor, Gérard Mourou, for work they did at the Laboratory for Laser Energetics. By Lindsey Valich Donna Strickland ’89 (PhD) still recalls the visit she took to the On- tario Science Centre when she was a child growing up in the town of Guelph, outside Toronto. Her father pointed to a laser display. “ ‘Donna, this is the way of the future,’ ” Strickland remembers him telling her. Lloyd Strickland, an electrical engineer, along with Donna’s moth- er, sister, and brother, was part of the family that “continually sup- ported and encouraged me through all my years of education,” Donna Strickland wrote in the acknowledgments of her PhD thesis, “De- velopment of an Ultra-Bright Laser and an Application to Multi- Photon Ionization.” She was captivated by that laser display. And since then, she says, “I’ve always thought lasers were cool.” Her passion for laser science research and her commitment to be- ing a “laser jock,” as she has called herself, has led her across North America, from Canada to the United States and back again. But it’s the work that she did as a graduate student at Rochester in the 1980s that has earned her the remarkable accolade of Nobel Prize laureate. When Strickland entered the University’s graduate program in op- tics, laser physicists were grappling with a thorny problem: how could they create ultrashort, high-intensity laser pulses that wouldn’t de- stroy the very material the laser was used to explore in the first place? Working with former Rochester engineering professor Gérard Mourou, Strickland developed and made workable a method to over- come the barrier. -
Caso Relativamente Recente
Perché chiamiamo “fondamentale” la Cenerentola della ricerca? (di M. Brunori) Neanche nel Pnrr si trovano speranze di cambiamento e iniziative coraggiose per la ricerca di base. Ma nelle scienze della vita non sono rare le scoperte nate da progetti di ricerca curiosity driven che richiedono tempo per portare risultati Soci dell'Accademia dei Lincei. (a cura di Maurizio Brunori, Prof. emerito di Chimica e Biochimica, Sapienza Università di Roma, Presidente emerito della Classe di Scienze FMN dell’Accademia dei Lincei) Nelle scienze della vita non sono infrequenti le scoperte innovative nate da progetti di ricerca di base, iniziati per cercare di comprendere qualche importante proprietà di un essere vivente, misteriosa ma ovviamente necessaria se è stata conservata nel corso dell’evoluzione. Questi progetti sono quelli che si iniziano per curiosità intellettuale, ma richiedono libertà di iniziativa, impegno pluriennale e molto coraggio in quanto di difficile soluzione. Un successo straordinario noto a molti è quello ottenuto dieci anni fa da due straordinarie ricercatrici, Emmanuelle Charpentier e Jennifer Doudna; che a dicembre hanno ricevuto dal Re di Svezia il Premio Nobel per la Chimica con la seguente motivazione: “for the development of a new method for genome editing”. Nel 2018 in occasione di una conferenza magistrale che la Charpentier tenne presso l’Accademia Nazionale dei Lincei, avevo pubblicato sul Blog di HuffPost un pezzo per commentare l’importanza della scoperta di CRISPR/Cas9, un kit molecolare taglia-e-cuci che consente di modificare con precisione ed efficacia senza precedenti il genoma di qualsiasi essere vivente: batteri, piante, animali, compreso l’uomo. NOBEL PRIZE Nobel Chimica Non era mai accaduto che due donne vincessero insieme il Premio Nobel. -
Table of Contents (PDF)
January 12, 2016 u vol. 113 u no. 2 From the Cover E249 Drought impacts on California forests E172 Kinases and prostate cancer metastasis E229 Potassium channel and sour taste 262 Tuning protein reduction potential 380 Lipid target of autoreactive T cells Contents THIS WEEK IN PNAS Cover image: Pictured is a 3D image of 237 In This Issue the canopy water content (CWC) of trees in the Jasper Ridge Biological Preserve at Stanford University, with low and high LETTERS (ONLINE ONLY) water content shown in red and blue, respectively. Gregory P. Asner et al. E105 Is nitric oxide important for the diastolic phase of the lymphatic found that CWC decreased measurably contraction/relaxation cycle? for an estimated 10.6 million hectares of Michael J. Davis forest, containing up to 888 million large E106 Reply to Davis: Nitric oxide regulates lymphatic contractions trees, between 2011 and 2015, with 1 Christian Kunert, James W. Baish, Shan Liao, Timothy P. Padera, and Lance L. Munn million hectares experiencing greater E107 Lion populations may be declining in Africa but not as Bauer et al. suggest than 30% CWC loss. The results suggest Jason Riggio, Tim Caro, Luke Dollar, Sarah M. Durant, Andrew P. Jacobson, Christian Kiffner, that if drought conditions in California Stuart L. Pimm, and Rudi J. van Aarde continue, forests might undergo E109 Reply to Riggio et al.: Ongoing lion declines across most of Africa warrant substantial changes. See the article by urgent action Asner et al. on pages E249–E255. Image Hans Bauer, Guillaume Chapron, Kristin Nowell, Philipp Henschel, Paul Funston, Luke T. -
The 2016 Nobel Prize in Chemistry
Pure Appl. Chem. 2016; 88(10-11): 917–918 Editorial Hugh D. Burrows* and Richard M. Hartshorn* The 2016 Nobel Prize in Chemistry DOI 10.1515/pac-2016-2005 Keywords: Ben L. Feringa; Jean-Pierre Sauvage; J. Fraser Stoddart; Nobel Prize in Chemistry; 2016. Pure and Applied Chemistry warmly congratulates Jean-Pierre Sauvage (University of Strasbourg, France), Sir J. Fraser Stoddart (Northwestern University, Evanston, IL, USA), and Bernard (Ben) L. Feringa (Univer- sity of Groningen, the Netherlands) on their award of the 2016 Nobel Prize in Chemistry. The citation from the Royal Swedish Academy of Sciences states that the award is “for the design and synthesis of molecu- lar machines”. Their work encompasses a broad spectrum of Chemistry, from elegant synthetic studies of catenanes, rotaxanes and other formerly considered exotic molecules, through coordination chemistry, and electron transfer reactions, to molecular switches and rotors driven by light and other external sources. They have all participated actively in IUPAC endorsed meetings and conference series, including the IUPAC World Congress in Chemistry, IUPAC International Conferences on Organic Synthesis (ICOS), Physical Organic Chemistry (ICPOC), and Coordination Chemistry (ICCC), and IUPAC International Symposia on Macrocyclic Chemistry (ISMC), Organometallic Chemistry Directed Towards Organic Synthesis (OMCOS), Novel Aromatic Compounds (ISNA), Carbohydrate Chemistry (ICS), the Chemistry of Natural Products ISCNP), and Photo- chemistry. Pure Appl. Chem. publishes collections of papers based upon authoritative lectures presented at such IUPAC endorsed events, in addition to IUPAC Recommendations, and Technical Reports. We are very pleased to highlight the following publications from these three Nobel Laureates that have been published in Pure and Applied Chemistry as a result of their involvement in these conferences. -
書 名 等 発行年 出版社 受賞年 備考 N1 Ueber Das Zustandekommen Der
書 名 等 発行年 出版社 受賞年 備考 Ueber das Zustandekommen der Diphtherie-immunitat und der Tetanus-Immunitat bei thieren / Emil Adolf N1 1890 Georg thieme 1901 von Behring N2 Diphtherie und tetanus immunitaet / Emil Adolf von Behring und Kitasato 19-- [Akitomo Matsuki] 1901 Malarial fever its cause, prevention and treatment containing full details for the use of travellers, University press of N3 1902 1902 sportsmen, soldiers, and residents in malarious places / by Ronald Ross liverpool Ueber die Anwendung von concentrirten chemischen Lichtstrahlen in der Medicin / von Prof. Dr. Niels N4 1899 F.C.W.Vogel 1903 Ryberg Finsen Mit 4 Abbildungen und 2 Tafeln Twenty-five years of objective study of the higher nervous activity (behaviour) of animals / Ivan N5 Petrovitch Pavlov ; translated and edited by W. Horsley Gantt ; with the collaboration of G. Volborth ; and c1928 International Publishing 1904 an introduction by Walter B. Cannon Conditioned reflexes : an investigation of the physiological activity of the cerebral cortex / by Ivan Oxford University N6 1927 1904 Petrovitch Pavlov ; translated and edited by G.V. Anrep Press N7 Die Ätiologie und die Bekämpfung der Tuberkulose / Robert Koch ; eingeleitet von M. Kirchner 1912 J.A.Barth 1905 N8 Neue Darstellung vom histologischen Bau des Centralnervensystems / von Santiago Ramón y Cajal 1893 Veit 1906 Traité des fiévres palustres : avec la description des microbes du paludisme / par Charles Louis Alphonse N9 1884 Octave Doin 1907 Laveran N10 Embryologie des Scorpions / von Ilya Ilyich Mechnikov 1870 Wilhelm Engelmann 1908 Immunität bei Infektionskrankheiten / Ilya Ilyich Mechnikov ; einzig autorisierte übersetzung von Julius N11 1902 Gustav Fischer 1908 Meyer Die experimentelle Chemotherapie der Spirillosen : Syphilis, Rückfallfieber, Hühnerspirillose, Frambösie / N12 1910 J.Springer 1908 von Paul Ehrlich und S. -
Die Woche Spezial
In cooperation with DIE WOCHE SPEZIAL >> Autographs>vs.>#NobelSelfie Special >> Big>Data>–>not>a>big>deal,> Edition just>another>tool >> Why>Don’t>Grasshoppers> Catch>Colds? SCIENCE SUMMIT The>64th>Lindau>Nobel>Laureate>Meeting> devoted>to>Physiology>and>Medicine More than 600 young scientists came to Lindau to meet 37 Nobel laureates CAREER WONGSANIT > Women>to>Women: SUPHAKIT > / > Science>and>Family FOTOLIA INFLAMMATION The>Stress>of>Ageing > FLASHPICS > / > MEETINGS > FOTOLIA LAUREATE > CANCER RESEARCH NOBEL > LINDAU > / > J.>Michael>Bishop>and GÄRTNER > FLEMMING > JUAN > / the>Discovery>of>the>first> > CHRISTIAN FOTOLIA Human>Oncogene EDITORIAL IMPRESSUM Chefredakteur: Prof. Dr. Carsten Könneker (v.i.S.d.P.) Dear readers, Redaktionsleiter: Dr. Daniel Lingenhöhl Redaktion: Antje Findeklee, Jan Dönges, Dr. Jan Osterkamp where>else>can>aspiring>young>scientists> Ständige Mitarbeiter: Lars Fischer Art Director Digital: Marc Grove meet>the>best>researchers>of>the>world> Layout: Oliver Gabriel Schlussredaktion: Christina Meyberg (Ltg.), casually,>and>discuss>their>research,>or>their> Sigrid Spies, Katharina Werle Bildredaktion: Alice Krüßmann (Ltg.), Anke Lingg, Gabriela Rabe work>–>or>pressing>global>problems?>Or> Verlag: Spektrum der Wissenschaft Verlagsgesellschaft mbH, Slevogtstraße 3–5, 69126 Heidelberg, Tel. 06221 9126-600, simply>discuss>soccer?>Probably>the>best> Fax 06221 9126-751; Amtsgericht Mannheim, HRB 338114, UStd-Id-Nr. DE147514638 occasion>is>the>annual>Lindau>Nobel>Laure- Geschäftsleitung: Markus Bossle, Thomas Bleck Marketing und Vertrieb: Annette Baumbusch (Ltg.) Leser- und Bestellservice: Helga Emmerich, Sabine Häusser, ate>Meeting>in>the>lovely>Bavarian>town>of> Ute Park, Tel. 06221 9126-743, E-Mail: [email protected] Lindau>on>Lake>Constance. Die Spektrum der Wissenschaft Verlagsgesellschaft mbH ist Kooperati- onspartner des Nationalen Instituts für Wissenschaftskommunikation Daniel>Lingenhöhl> GmbH (NaWik). -
Chemical Synthesis
www.iupac2017.org Adriano D. Andricopulo Chairman of the IUPAC-2017 Organizing Committee Brazil: Key Figures and Facts • Brazil is Latin America's largest country (47% of the South America Continent) and the fifth largest country in the world • Population: 204 million people (the fifth most populous in the world ) • Language: Portuguese . Official currency: Brazilian Real (1.00 USD = R$ 3.12) • Brazil has the world’s ninth-largest economy and the largest in Latin America Brazil: Key Figures and Facts . São Paulo has the largest population, industrial complex, and economic production in Brazil . Population: 12 million people (45 million in SP state) . It is the largest city in South America, and the fifth largest in the world . São Paulo State is responsible for 40% of the Brazilian GDP . Climate: humid subtropical, temperatures in July: 12 and 22°C (54°F and 72°F) . Number of tourists in 2016: > 18 million WTC Events Center and Sheraton WTC Hotel are the most complete complex for events in Latin America Approximately 12,000 m² are available and divided into 60 flexible spaces Services: Parking Restaurants Banks Currency exchange Travel agency Pharmacies Hairdresser’s Stationery General Aspects - 9 Plenary Lectures, including 4 Noble Laureates - About 120 Sessions in 12 major themes - Several Keynote, Invited, Oral and Young Scientists Opening Ceremony Special Symposia Welcome Reception 3 Poster Sessions Half-day Social Program Gala Dinner Exhibition Plenary Lectures Sir J. Fraser Stoddart (Nobel Prize 2016) Department of Chemistry -
JACQUES DUBOCHET (75) Es Ist Derzeit Nicht Leicht, an Jacques Dubochet Heranzukom- Men
NoBelpreis TexT Mathias Plüss Bilder anoush abrar JACQUES DUBOCHET (75) Es ist derzeit nicht leicht, an Jacques Dubochet heranzukom- men. Ist man aber einmal bei ihm, so hat man ihn ganz für aus dem Waadtland ist ein Mensch wie du sich. Nicht nur lässt er sich keine Sekunde ablenken – er inte- und ich. Und gerade darum vielleicht ressiert sich auch für sein Gegenüber. Er pflegt Kolleginnen der ungewöhnlichste Nobelpreisträger, und Kollegen aus allen möglichen Disziplinen zu sich zum Essen einzuladen und mit Fragen zu löchern. Zu mir sagt er, den man sich vorstellen kann. als wir auf dem Weg zur Metro in Lausanne sind: «Und was Mit unserem Autor hat er eine kleine sind Sie für ein Mensch?» Zugfahrt gemacht. Dubochet ist 1942 in Aigle VD geboren. Er wuchs im Wal- lis und im Waadtland auf. In der Schule hatte er Mühe, konn- te aber dank verständnisvoller Lehrer die Matura machen. Er studierte Physik und wechselte dann zur Biologie. Die Statio- nen seiner Karriere waren Lausanne, Genf, Basel, Heidel- berg. Von 1987 bis 2007 war er Professor für Biophysik an der Universität Lausanne. Er ist mit einer Basler Künstlerin ver- heiratet und hat zwei erwachsene Kinder. Auch nach seiner Emeritierung engagiert er sich weiterhin: zum Beispiel im von ihm entwickelten Studienprogramm «Biologie und Ge- sellschaft», aber auch als Lokalpolitiker der SP an seinem Wohnort Morges VD. 4747 — — 20172017 DASDAS MAGAZIN MAGAZIN N° N° 20 «ICH VERSTEHE NICHTS VON CHEMIE» 4747 — — 20172017 DASDAS MAGAZIN MAGAZIN N° N° In der Schule Probleme, heute Nobelpreisträger: Jacques Dubochet aus Morges VD. Anfang Oktober gab das Stockholmer Nobelpreiskomitee be- … auch Luc Montagnier, der Entdecker des Aids-Vi- kannt, dass Jacques Dubochet den Chemie-Nobelpreis 2017 rus, entwickelte sehr bizarre Ideen. -
DONNA STRICKLAND, PH.D. Professor, University of Waterloo
DONNA STRICKLAND, PH.D. Professor, University of Waterloo Donna Strickland is a professor in the Department of Physics and Astronomy at the University of Waterloo and is one of the recipients of the Nobel Prize in Physics 2018 for developing chirped pulse amplification with Gérard Mourou, her PhD supervisor at the time. They published this Nobel-winning research in 1985 when Strickland was a PhD student at the University of Rochester in New York state. Together they paved the way toward the most intense laser pulses ever created. The research has several applications today in industry and medicine — including the cutting of a patient’s cornea in laser eye surgery, and the machining of small glass parts for use in cell phones. Strickland was a research associate at the National Research Council Canada, a physicist at Lawrence Livermore National Laboratory and a member of technical staff at Princeton University. In 1997, she joined the University of Waterloo, where her ultrafast laser group develops high-intensity laser systems for nonlinear optics investigations. Strickland was named a Companion of the Order of Canada. She is a recipient of a Sloan Research Fellowship, a Premier’s Research Excellence Award and a Cottrell Scholar Award. She received the Rochester Distinguished Scholar Award and the Eastman Medal from the University of Rochester. Strickland served as the president of the Optical Society (OSA) in 2013 and is a fellow of OSA, the Royal Society of Canada, and SPIE (International Society for Optics and Photonics). She is an honorary fellow of the Canadian Academy of Engineering as well as the Institute of Physics. -
Nobel Laureates Endorse Joe Biden
Nobel Laureates endorse Joe Biden 81 American Nobel Laureates in Physics, Chemistry, and Medicine have signed this letter to express their support for former Vice President Joe Biden in the 2020 election for President of the United States. At no time in our nation’s history has there been a greater need for our leaders to appreciate the value of science in formulating public policy. During his long record of public service, Joe Biden has consistently demonstrated his willingness to listen to experts, his understanding of the value of international collaboration in research, and his respect for the contribution that immigrants make to the intellectual life of our country. As American citizens and as scientists, we wholeheartedly endorse Joe Biden for President. Name Category Prize Year Peter Agre Chemistry 2003 Sidney Altman Chemistry 1989 Frances H. Arnold Chemistry 2018 Paul Berg Chemistry 1980 Thomas R. Cech Chemistry 1989 Martin Chalfie Chemistry 2008 Elias James Corey Chemistry 1990 Joachim Frank Chemistry 2017 Walter Gilbert Chemistry 1980 John B. Goodenough Chemistry 2019 Alan Heeger Chemistry 2000 Dudley R. Herschbach Chemistry 1986 Roald Hoffmann Chemistry 1981 Brian K. Kobilka Chemistry 2012 Roger D. Kornberg Chemistry 2006 Robert J. Lefkowitz Chemistry 2012 Roderick MacKinnon Chemistry 2003 Paul L. Modrich Chemistry 2015 William E. Moerner Chemistry 2014 Mario J. Molina Chemistry 1995 Richard R. Schrock Chemistry 2005 K. Barry Sharpless Chemistry 2001 Sir James Fraser Stoddart Chemistry 2016 M. Stanley Whittingham Chemistry 2019 James P. Allison Medicine 2018 Richard Axel Medicine 2004 David Baltimore Medicine 1975 J. Michael Bishop Medicine 1989 Elizabeth H. Blackburn Medicine 2009 Michael S. -
Ripples in Spacetime
editorial Ripples in spacetime The 2017 Nobel prize in Physics has been awarded to Rainer Weiss, Barry C. Barish and Kip S. Thorne “for decisive contributions to the LIGO detector and the observation of gravitational waves”. It is, frankly, difficult to find something original to say about the detection of gravitational waves that hasn’t been said already. The technological feat of measuring fluctuations in the fabric of spacetime less than one-thousandth the width of an atomic nucleus is quite simply astonishing. The scientific achievement represented by the confirmation of a century-old prediction by Albert Einstein is unique. And the collaborative effort that made the discovery possible — the Laser Interferometer Gravitational-Wave Observatory (LIGO) — is inspiring. Adapted from Phys. Rev. Lett. 116, 061102 (2016), under Creative Commons Licence. Rainer Weiss and Kip Thorne were, along with the late Ronald Drever, founders of the project that eventually became known Barry Barish, who was the director Last month we received a spectacular as LIGO. In the 1960s, Thorne, a black hole of LIGO from 1997 to 2005, is widely demonstration that talk of a new era expert, had come to believe that his objects of credited with transforming it into a ‘big of gravitational astronomy was no interest should be detectable as gravitational physics’ collaboration, and providing the exaggeration. Cued by detections at LIGO waves. Separately, and inspired by previous organizational structure required to ensure and Virgo, an interferometer based in Pisa, proposals, Weiss came up with the first it worked. Of course, the passion, skill and Italy, more than 70 teams of researchers calculations detailing how an interferometer dedication of the thousand or so scientists working at different telescopes around could be used to detect them in 1972. -
The Nobel Prize in Chemistry 2013 the Royal Swedish Academy of Sciences Has Decided to Award the Nobel Prize in Chemistry for 2013 To
PRESSMEDDELANDE Press release 9 October 2013 The Nobel Prize in Chemistry 2013 The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry for 2013 to Martin Karplus Michael Levitt Arieh Warshel Université de Strasbourg, France and Stanford University School of Medicine, University of Southern California, Harvard University, Cambridge, MA, USA Stanford, CA, USA Los Angeles, CA, USA “for the development of multiscale models for complex chemical systems” The computer — your Virgil in the world of atoms Chemists used to create models of molecules This year’s Nobel Laureates in chemistry took the best using plastic balls and sticks. Today, the modelling from both worlds and devised methods that use both is carried out in computers. In the 1970s, Martin classical and quantum physics. For instance, in simu- Karplus, Michael Levitt and Arieh Warshel laid the lations of how a drug couples to its target protein in foundation for the powerful programs that are used the body, the computer performs quantum theoretical to understand and predict chemical processes. calculations on those atoms in the target protein that Computer models mirroring real life have become interact with the drug. The rest of the large protein is crucial for most advances made in chemistry today. simulated using less demanding classical physics. Chemical reactions occur at lightning speed. In a fraction Today the computer is just as important a tool for of a millisecond, electrons jump from one atomic nucleus chemists as the test tube. Simulations are so realistic to the other. Classical chemistry has a hard time keeping that they predict the outcome of traditional experiments.