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GAIN A NEW PERSPECTIVE

JULY 6-9, 2015 » BOSTON

PROGRAM BOOK PLATINUM SPONSOR TABLE OF CONFERENCE CONTENTS OVERVIEW PAGE 4 EVENT HIGHLIGHTS PAGE

5 HOTEL MAP PAGES 6 FEATURED SPEAKERS PAGES

7 AGENDA PAGES

8-15 TECHNICAL BREAKOUT SESSIONS PAGES 16-18

SPONSORS PAGES 19-21 CONFERENCE EVENT OVERVIEW HIGHLIGHTS DESTINATION STATION: NASA’s International Space Station Program national awareness campaign and traveling exhibit is making a stop in Boston during the 2015 ISS R&D Conference. elcome! The 2015 ISS R&D Conference is your connection to the Destination Station promotes research opportunities, educates communities about activities on the International latest innovations, breakthroughs and discoveries onboard the Space Station, and communicates the real and potential International Space Station. We’ve brought together the leading impacts of space station activity on our everyday lives. W Stop by the registration desk for more information. minds in scientific research from commercial and academic communities. The fourth annual conference focuses on new discoveries in microgravity in a range of focus areas including life sciences, physical sciences, technology development and remote sensing. ISS 3D DISPLAY: REGISTRATION: Your conference registration Explore the International Space Station like you’ve fee includes all sessions, continental breakfasts, never seen it before. Stop by Floor 4 to gain a new breaks and receptions, and two of the three hosted perspective on the space station with this hands-on exhibit that offers 360-degree internal and external lunches. The keynote luncheon featuring CNN’s views of the space station. Rachel Crane is an additional $50.00; see the registration desk on Floor 4 to inquire if space is still available. If you have any questions during the conference, please visit the registration desk to speak with the conference staff. GAIN A NEW PERSPECTIVE» BOSTON BADGES: Keep your badge displayed during JULY 7-9, 2015 “ASK AN ISS EXPERT” EXHIBIT: the conference to access all the venues. CASIS and NASA have developed a brand-new inter- active exhibit to connect conference attendees to a PLATINUM SPONSOR: APP: Be sure to download our free conference network of space experts. The Ask An ISS Expert exhibit, located on Floor 4, is your one-stop shop for resources, app to reference agenda times, locations and information and key contacts. Have an innovative idea? session descriptions quickly. Search “ISSRDC” Looking to learn more about hardware? Curious about within your app store. the space station’s research capabilities? Stop by the Ask an ISS Expert exhibit today and chat with a team of experts that support the ISS National Laboratory. SOCIAL: Follow us on for conference updates and announcements, and be sure to use #ISSRDC to join the conversation.

CASIS: @iss-casis NASA: @ www.issconference.org AAS: @astrosociety MARKETPLACE EXHIBITS: Make valuable connections in the marketplace exhibit area. CASIS and NASA have partnered with experienced companies that provide the specialized services you’ll HOSTS need to get your science to International Space Station, and many of these companies will have representatives on-hand to talk and answer your questions during ISS R&D Conference.

www.astronautical.org www.nasa.gov www.iss-casis.org JULY 7-9, 2015 » BOSTON 5 HOTEL CHAD ANDERSON: Managing Director, Space Angels Network FEATURED MAP ISS 3D DISPLAY JEFF BINGHAM: Former Senior Adviser, SPEAKERS FOURTH FLOOR US Senate Commerce, Science and Transportation Committee FLOOR 4 FRANK L. CULBERTSON: Executive Vice President and President, Space NANTUCKET Systems Group, Orbital ATK HYANNIS YARMOUTH VINEYARD

PROVINCE- MARY LYNNE DITTMAR: President, TOWN

ORLEANS FAL- Dittmar Associates MOUTH MARYBETH EDEEN: Manager, ISS SALON K SALON A Research Integration Office, NASA

TRIUM A WILLIAM H. GERSTENMAIER: AREA Associate SALON J SALON B ELON MUSK Administrator, Human Exploration SALON G SALON F SALON E CEO and Lead Designer of and Operations, NASA JANICE L. HESS: President, Teledyne SALON I SALON C SpaceX; Product Architect Brown Engineering Segment, and CEO of Tesla Motors; President, Engineered Systems, Chairman of SolarCity SALON H SALON D Teledyne Technologies Inc. GREG JOHNSON: President and Executive Director, CASIS

JEFF MANBER: Managing Director, “ASK AN NanoRacks LLC FEATURED SESSIONS, ISS EXPERT” ANGUS G. MCQUILKEN: Vice President LUNCHEONS EXHIBIT for Communications and Marketing, Massachusetts Life Sciences Center REGISTRATION DAVID MILLER: Chief Technologist, NASA RACHEL CRANE CNN Digital Correspondent DAVA NEWMAN: Deputy MARKETPLACE EXHIBITS, Administrator, NASA THIRD FLOORNETWORKING RECEPTIONS NASA ASTRONAUTS FLOOR 3 STEPHAN RECKIE: Managing Director, Angelus Funding SPONSOR BREAKFASTS JULIE ROBINSON: Chief Scientist, (INVITE ONLY) International Space Station CADY Program, NASA COLEMAN KEN SAVIN: Director of Innovation, SAM SCIMEMI: Director for Eli Lilly International Space Station, Human Exploration and Operations Mission Directorate, NASA HQ SUNITA JOHN SHANNON: International Space WILLIAMS Station Program Manager, Boeing MARK SIRANGELO: Executive Vice President, Sierra Nevada Corporation Space Systems KAREN NYBERG ELLEN STOFAN: Chief Scientist, NASA

MICHAEL T. SUFFREDINI: Manager, International Space Station TECHNICAL BREAKOUT SESSIONS OPENING RECEPTION Program, NASA JULY 7-9, 2015 » BOSTON 7 MONDAY, JULY 6

3:00 – 6:00 PM Registration Open AGENDA AT AGENDA 4:30 – 6:00 PM New User Workshop A GLANCE DAY 1 6:00 – 8:00 PM Opening Reception MONDAY, JULY 6 TUESDAY, JULY 7 TIME EVENT ROOM, FLOOR 7:00 – 8:00 AM Registration, Continental Breakfast & Networking 3:00 – 6:00 PM Registration Open Atrium Foyer • 4 8:00 – 8:15 AM Welcome & Opening Remarks 4:30 – 6:00 PM New User Workshop Berkeley • 3 8:15 – 8:45 AM An ISS Welcome, Michael T. Suffredini

8:45 – 10:00 AM A Conversation with Elon Musk 6:00 – 8:00 PM Opening Reception Atrium • 3

10:00 – 10:15 AM BREAK 10:15 – 11:30 AM International Space Station: Catalyst for the Future 11:30 – 1:00 PM Biomedical Advancements from Space-based Protein Crystal Growth NEW USER WORKSHOP FEATURED SPEAKER 1:00 – 2:15 PM Best of 2015 ISS Awards Ceremony and Lunch CADY COLEMAN, NASA ASTRONAUT 2:15 – 4:15 PM TECHNICAL BREAKOUT SESSIONS 4:15 – 4:30 PM BREAK NASA Astronaut Cady Coleman will join the New User Workshop 4:30 – 5:30 PM New Space: Funding New Ideas and Businesses in the Emerging Commercial Space Sector at ISS R&D Conference to highlight the exciting science and technology development projects that are being conducted on 5:30 – 7:30 PM Networking Reception the International Space Station. Coleman provides keen insight as WEDNESDAY, JULY 8 a veteran astronaut and as a key figure within NASA’s International

7:00 – 8:00 AM Registration, Continental Breakfast & Networking Space Station Program. She will offer a knowledgeable perspective on the increased capabilities of the space station to support innovative R&D 8:00 – 8:15 AM Welcome and what this means for new users. 8:15 – 9:30 AM The Evolving ISS Lab: Improvements to Enable New Research and Utilization

9:30 – 11:00 AM Viewpoints: Leveraging ISS to Enable LEO Commercialization

11:00 – 11:15 AM BREAK 11:15 – 12:30 PM Stem Cell Research: Impact on Therapeutics

11:15 – 12:30 PM Commercial Remote Sensing from the ISS NEW USER WORKSHOP 12:45 – 2:15 PM ISS User Innovation Keynote (featuring CNN’s Rachel Crane) This workshop is designed to connect and educate 2:15 – 4:15 PM TECHNICAL BREAKOUT SESSIONS prospective researchers, entrepreneurs and financiers 4:15 – 4:30 PM BREAK about the benefits, resources, and accessibility of using 4:30 – 6:00 PM Good Health: Translating Precision Medicine on the ISS National Lab to Human Wellness on Earth our nation’s only orbiting laboratory. In this engaging session, you’ll hear directly from R&D users, astronauts 6:30 – 8:00 PM Networking Reception and program leaders about the best ways to accelerate THURSDAY, JULY 9 your International Space Station (ISS) R&D initiatives. 7:00 – 8:00 AM Registration, Continental Breakfast & Networking Discover how to leverage the unique capabilities and microgravity environment of the ISS to support 8:00 – 8:15 AM Welcome research and business model development. 8:15 – 9:45 AM Beyond LEO: The Role of ISS in Support of Exploration Learn why new-to-space users are conducting innovative 9:45 – 10:00 AM BREAK research and technology development in space 10:00 – 11:00 AM Materials Science Research: Testing and Manufacturing in Space Review and discuss benefits of research and technology STEM on the ISS : How the ISS National Lab is Influencing Students and Educators in the Area of STEM demonstrations in microgravity 11:00 – 12:15 PM Education Get insight into the ISS mission, capabilities, and 12:30 – 2:15 PM Astronaut Keynote Address & Lunch development roadmap 2:15 – 4:15 PM TECHNICAL BREAKOUT SESSIONS Get connected to key access points for using the ISS National 4:30 – 5:30 PM Can Humans Survive 1,000 Days in Space? The Impact of ISS One Year Missions Laboratory via CASIS and NASA, as well as to conference mentors who will help you further engage with the ISS R&D community 5:30 – 5:45 PM Conference Closing Remarks JULY 7-9, 2015 » BOSTON 9

INTERNATIONAL SPACE STATION: AGENDA CATALYST FOR THE FUTURE In addition to being one of humankind’s greatest DAY 2 accomplishments, the International Space Station is an idea—a catalyst for the future, enabling the visions of nations, TUESDAY, JULY 7 scientists, explorers, industrialists and entrepreneurs. This panel TIME EVENT ROOM • FLOOR offers perspectives on the role of the ISS in realizing these visions, discussing such issues as: 7:00 – 8:00 AM Registration, Continental Breakfast & Networking Atrium Foyer • 4 The nature of international and commercial relationships 8:00 – 8:15 AM Welcome & Opening Remarks Salon F • 4 established throughout the ISS program 8:15 – 8:45 AM An ISS Welcome, Michael T. Suffredini Salon F • 4 The role of the ISS as a “first step” away from our home planet on the path of human exploration BIOMEDICAL ADVANCEMENTS FROM 8:45 – 10:00 AM A Conversation with Elon Musk Salon F • 4

Opportunities unleashed by the presence of a National SPACE-BASED PROTEIN CRYSTAL GROWTH Elucidating protein structures promises to unravel complexities 10:00 – 10:15 AM BREAK Lab onboard the ISS of human health and advance pharmaceutical development. 10:15 – 11:30 AM International Space Station: Catalyst for the Future Salon F • 4 SPEAKERS: Some proteins, however, have been difficult to crystallize • MARY LYNNE DITTMAR, PRESIDENT, DITTMAR ASSOCIATES in sufficient quality or quantity on Earth to permit structure Biomedical Advancements from Space-based determination. The benefits of microgravity for protein crystal 11:30 – 1:00 PM Salon F • 4 (MODERATOR) Protein Crystal Growth • WILLIAM GERSTENMAIER, NASA ASSOCIATE ADMINISTRATOR, growth offer a solution to these obstacles—the growth of HUMAN EXPLORATION AND OPERATIONS MISSION DIRECTORATE larger, more well-ordered crystals. This session will highlight 1:00 – 2:15 PM Best of 2015 ISS Awards Ceremony and Lunch Salons A-E • 4 • MARK SIRANGELO, CORPORATE VICE PRESIDENT, experiments that exploit the space environment for improved SIERRA NEVADA CORPORATION SPACE SYSTEMS crystal growth—toward the improved understanding of human TECHNICAL BREAKOUT SESSIONS* • ROB FERL, DIRECTOR FOR INTERDISCIPLINARY CENTER FOR disease and the acceleration of structure-based drug design. Biological Insights In Space Berkeley • 3 BIOTECHNOLOGY RESEARCH, UNIVERSITY OF SPEAKERS: • LARRY DELUCAS, DIRECTOR, CENTER FOR STRUCTURAL Living in Space Clarendon • 3 BIOLOGY, UNIVERSITY OF ALABAMA – BIRMINGHAM 2:15 – 4:15 PM (MODERATOR) Looking at Earth Dartmouth • 3 • YOSHIHIRO URADE, PROFESSOR, TSUKUBA UNIVERSITY • JOSEPH NG, PRESIDENT, IEXPRESS GENES Advances in Communications Exeter • 3 • PAUL REICHERT, ASSOCIATE PRINCIPAL SCIENTIST, Sensors and Components Fairfield • 3 MERCK LABORATORIES 4:15 – 4:30 PM BREAK

NEW SPACE: FUNDING NEW IDEAS New Space: Funding New Ideas and Businesses 4:30 – 5:30 PM Salons A-E • 4 AND BUSINESSES IN THE EMERGING in the Emerging Commercial Space Sector

COMMERCIAL SPACE SECTOR 5:30 – 7:30 PM Networking Reception Gloucester • 3 This session is designed to stimulate discussion about the capital investments and grants fueling the growth of “New *SEE PAGES 16-18 FOR TECHNICAL BREAKOUT DESCRIPTIONS Space” businesses. Investor capital is beginning to flow into the emerging commercial space sector as never before. Angel funds and networks are looking to seed new businesses, venture capital is turning an interested eye to the growing A CONVERSATION WITH ELON MUSK number of successful early stage space companies, and startup accelerators as well as public-private partnerships are driving ELON MUSK, CEO AND LEAD DESIGNER, SPACEX; money behind intriguing ideas for products and businesses in PRODUCT ARCHITECT AND CEO, TESLA MOTORS; CHAIRMAN, SOLARCITY commercial space. SPEAKERS: Join fellow researchers and space enthusiasts as Elon Musk, the transformative entrepreneur responsible for PayPal, Tesla Motors and SpaceX, addresses the audience as ISS R&D’s • STEPHAN RECKIE, MANAGING DIRECTOR, ANGELUS FUNDING (MODERATOR) featured keynote speaker. With this unique opportunity, attendees will hear from one of this generation’s most intriguing innovators about the future of space exploration and the • AMIR BLACHMAN, PRINCIPAL OF THE SPACE ANGELS NETWORK International Space Station. • SCOTT BAILEY, MANAGING DIRECTOR, MASS CHALLENGE • ANGUS MCQUILKEN, VICE PRESIDENT FOR COMMUNICATIONS AND MARKETING, MASSACHUSETTS LIFE SCIENCE CENTER

JULY 7-9, 2015 » BOSTON 11 understanding of fundamental stem cell biology limits our ability THE EVOLVING ISS LAB: to reliably differentiate stem cells into specific types of mature AGENDA IMPROVEMENTS TO ENABLE NEW cells with high yield and purity. A promising approach to filling these knowledge gaps is to study stem cells in microgravity. DAY 3

RESEARCH, AND UTILIZATION Experiments in true microgravity onboard the International Learn more about what the International Space Station Program is Space Station promise to produce even more robust results than WEDNESDAY, JULY 8 doing to fully develop the ISS into a world-renowned laboratory in the compelling preliminary findings from experiments on Earth space, enabling discoveries in science and technology that benefit TIME EVENT ROOM • FLOOR conducted primarily in simulated microgravity. This panel will life on Earth and the exploration of the universe. This session will discuss recent findings from both environments. 7:00 – 8:00 AM Registration, Continental Breakfast & Networking Atrium Foyer • 4 highlight four thrust areas—Integration Process Improvements, New Acquisition Strategies, Facility Upgrades and Operational SPEAKERS: 8:00 – 8:15 AM Welcome Salons E-F • 4 Updates—that are enabling increased utilization of ISS and new • NEAL PELLIS, DIRECTOR, DIVISION OF SPACE LIFE SCIENCES, UNIVERSITIES SPACE RESEARCH ASSOCIATION (MODERATOR) The Evolving ISS Lab: Improvements to entrepreneurial opportunities for private business to quickly 8:15 – 9:30 AM Salons E-F • 4 explore and test multiple business cases in a cost effective and • DR. CHUNHUI XU, ASSOCIATE PROFESSOR, EMORY UNIVERSITY Enable New Research and Utilization “terrestrial” timeframe. SCHOOL OF MEDICINE • ELIZABETH BLABER, POST-DOCTORAL FELLOW, NASA AMES 9:30 – 11:00 AM Viewpoints: Leveraging ISS to Enable LEO Commercialization Salons E-F • 4 SPEAKERS: • ROBERT SCHWARTZ, HUGH ROY AND LILLIE CRANZ CULLEN • MARYBETH EDEEN, MANAGER, ISS RESEARCH INTEGRATION DISTINGUISHED UNIVERSITY PROFESSOR, DEPARTMENT OF 11:00 – 11:15 AM BREAK OFFICE, NASA (MODERATOR) BIOLOGY AND BIOCHEMISTRY, UNIVERSITY OF • RYAN PROUTY, LEAD, REVOLUTIONIZE ISS FOR SCIENCE AND 11:15 – 12:30 PM Stem Cell Research: Impact on Therapeutics Salons E-F • 4 EXPLORATION (RISE) COMMERCIAL REMOTE SENSING FROM THE ISS 11:15 – 12:30 PM Commercial Remote Sensing from the ISS † Clarendon • 3 • DANA WEIGEL, MANAGER, ISS VEHICLE OFFICE, NASA As commercial remote sensing becomes more viable and • MIKE READ, MANAGER, ISS NATIONAL LAB OFFICE, NASA ISS becomes a more capable sensor host, CASIS, through its 12:45 – 2:15 PM ISS User Innovation Keynote (featuring CNN’s Rachel Crane) Salons E-F • 4 Good Earth Campaign, will seek opportunities for commercial, VIEWPOINTS: LEVERAGING ISS academic and government entities to evaluate remote sensing TECHNICAL BREAKOUT SESSIONS* technologies with commercial or humanitarian benefit. This TO ENABLE LEO COMMERCIALIZATION Drug Discovery and Delivery Berkeley • 3 NASA and its International Space Station partners currently technical session provides an interactive forum for those represent the primary suppliers as well as consumers of interested in applying or improving ISS as a remote sensing Plants and Omics in Space Clarendon • 3 services in Low Earth Orbit. However, NASA has a larger vision platform. Participants will have the opportunity to share 2:15 – 4:15 PM of sustained economic activity in LEO enabled by human inquiries and information with five companies who currently Developing Commercial Capabilities and Services Dartmouth • 3 spaceflight. Join the 4th Annual ISS R&D Conference for a manage or plan to develop remote sensing capabilities and Crew Research and Performance Exeter • 3 conversation with a spectrum of the space industry’s established infrastructure onboard the ISS. and emerging players, as we discuss how best to leverage the Technology Developments on ISS Fairfield • 3 ISS to enable a robust commercialization of LEO leading to GOOD HEALTH: THE IMPACT OF SPACE 4:15 – 4:30 PM sustainable economic activity before the ISS end of life. SCIENCE ON PRECISION MEDICINE BREAK SPEAKERS: We are entering the era of precision medicine, as researchers 4:30 – 6:00 PM Good Health: The Impact of Space Science on Precision Medicine Salons E-F • 4 • JEFF BINGHAM, FORMER SENIOR ADVISER, US SENATE and scientists levy new resources and collaborate to accelerate COMMERCE, SCIENCE AND TRANSPORTATION COMMITTEE progress towards improving human health globally. CASIS and 6:30 – 8:00 PM Networking Reception Gloucester • 3 (CO-MODERATOR) NASA are embarking on a new endeavor to improve human † • SAM SCIMEMI, DIRECTOR FOR INTERNATIONAL SPACE wellness: Campaign Good Health. Together, we are maximizing the THIS SESSION WILL RUN PARALLEL WITH THE STEM CELL SESSION STATION, HUMAN EXPLORATION AND OPERATIONS MISSION research capabilities of the ISS National Laboratory to gain greater *SEE PAGES 16-18 FOR TECHNICAL BREAKOUT DESCRIPTIONS DIRECTORATE – NASA HQ (CO-MODERATOR) insight into human diseases using human and animal model • JOHN SHANNON, ISS PROGRAM MANAGER, BOEING studies in space. Leaders from across industry and academia ISS USER INNOVATION KEYNOTE LUNCHEON • FRANK CULBERTSON, PRESIDENT, SPACE SYSTEMS GROUP, will provide an overview of the campaign, outline research and ORBITAL ATK technology development initiatives, and discuss how data shared RACHEL CRANE, CNN DIGITAL CORRESPONDENT

• JEFF MANBER, MANAGING DIRECTOR, NANORACKS LLC in precision medicine is accelerating groundbreaking disease • JANICE L. HESS, PRESIDENT, TELEDYNE BROWN ENGINEERING, research and addressing global health challenges on Earth. CNN’s Rachel Crane will explore how new users of the International Space Station are pushing SEGMENT PRESIDENT, ENGINEERED SYSTEMS, TELEDYNE SPEAKERS: the boundaries of both science and innovation to translate space station utilization into benefits TECHNOLOGIES INCORPORATED for Earth. Will new consumer products be developed from space-based research? How are major • JULIE ROBINSON, NASA’S (MODERATOR) players in the pharmaceutical industry leveraging the space station’s unique environments? How • ANITA GOEL, CHAIRMAN AND CEO, NANOBIOSYM STEM CELL RESEARCH: will 3D printing enable capabilities never before possible? Don’t miss this thought-provoking session • STEVEN R. STEINHUBL, DIRECTOR OF DIGITAL MEDICINE, that examines the unique possibilities enabled by the ISS National Laboratory. IMPACT ON THERAPEUTICS SCRIPPS TRANSLATIONAL SCIENCE INSTITUTE Stem cell biology has the potential to transform broad • JOAN A. MCGOWAN, DIRECTOR, DIVISION OF MUSCULOSKELETAL SPEAKERS: fields from discovery science to regenerative medicine. The DISEASES, NATIONAL INSTITUTES OF HEALTH • RACHEL CRANE, CNN (MODERATOR) application of stem cells for drug screening, patient-specific • MARK SHELHAMER, HUMAN RESEARCH PROGRAM CHIEF • KEN SAVIN, DIRECTOR OF INNOVATION, ELI LILLY disease modeling, and tissue-specific repair is dependent on SCIENTIST, NASA’S JOHNSON SPACE CENTER • JASON DUNN, CO-FOUNDER AND CHIEF TECHNOLOGY OFFICER, MADE IN SPACE a thorough understanding of the mechanisms that regulate • TIMOTHY YEATMAN, PRESIDENT, GIBBS RESEARCH INSTITUTE • GREG JOHNSON, PRESIDENT AND EXECUTIVE DIRECTOR, CASIS stem cell growth and differentiation. Currently, an incomplete AND DIRECTOR, GIBBS CANCER CENTER • JULIE ROBINSON, CHIEF SCIENTIST, INTERNATIONAL SPACE STATION PROGRAM, NASA JULY 7-9, 2015 » BOSTON 13 BEYOND LEO: THE ROLE OF ISS AGENDA IN SUPPORT OF EXPLORATION Beyond Low Earth Orbit, commercial capabilities and offerings DAY 4 will be needed—together with international collaboration and new relationships between government, constituents such THURSDAY, JULY 9 as international consortia, and industry partners—in order TIME EVENT ROOM • FLOOR to successfully address the challenges and promise of deep space exploration. This panel session will explore key questions 7:00 – 8:00 AM Registration, Continental Breakfast & Networking Atrium Foyer • 4 associated with international and commercial partnerships in STEM ON THE ISS: HOW THE ISS NATIONAL 8:00 – 8:15 AM Welcome Salons E-F • 4 support of exploration beyond LEO. LAB IS INFLUENCING STUDENTS AND EDU- SPEAKERS: 8:15 – 9:45 AM Beyond LEO: The Role of ISS in Support of Exploration Salons E-F • 4 • MARY LYNNE DITTMAR, PRESIDENT, DITTMAR ASSOCIATES CATORS IN THE AREA OF STEM EDUCATION 9:45 – 10:00 AM (MODERATOR) While space has always inspired student interest in science, BREAK technology engineering and mathematics (STEM), the • DAVA NEWMAN, DEPUTY ADMINISTRATOR, NASA 10:00 – 11:00 AM Materials Science Research: Testing and Manufacturing in Space Salons E-F • 4 International Space Station is an incredible platform to facilitate • ELLEN STOFAN, CHIEF SCIENTIST, NASA student scientific inquiry and experimentation, thus providing • DAVID MILLER, CHIEF TECHNOLOGIST, NASA STEM on the ISS : How the ISS National Lab is Influencing an authentic connection to space for students. Come learn 11:00 – 12:15 PM Salons E-F • 4 Students and Educators in the Area of STEM Education MATERIALS SCIENCE RESEARCH: about STEM education programs that are leveraging access to the space station to impact student communities across the 12:30 – 2:15 PM Astronaut Keynote Address & Lunch Salons E-F • 4 TESTING AND MANUFACTURING IN SPACE country—from the students themselves! As International Space Station experiments study new SPEAKERS: TECHNICAL BREAKOUT SESSIONS* materials, and with the station’s recent 3D printing capability, • JEFFREY BENNETT, FOUNDER, BIG KID SCIENCE (MODERATOR) more opportunities for manufacturing specific materials Space Biology Tools Berkeley • 3 • KATHY DUQUESNAY, EDUCATOR, DUCHESNE ACADEMY, CASIS in the microgravity environment are emerging. Currently, NATIONAL DESIGN CHALLENGE Cell and Microbiology in Space Clarendon • 3 most materials synthesis investigations on the ISS focus on • MATTHEW BROWN, EDUCATOR, LAKEWOOD HIGH SCHOOL, 2:15 – 4:15 PM understanding fundamental scientific phenomena. This panel NASA HUNCH Materials Manufacturing and Function in Space Dartmouth • 3 will address several questions related to this field. For example, • KELLYE VOIGT, COMMUNITY PROGRAM DIRECTOR FOR NORTH What is the future for potential larger scale manufacturing in CHARLESTON, STUDENT SPACEFLIGHT EXPERIMENTS PROGRAM STEM Programs and Processes Exeter • 3 space? Are there materials that can only be developed in space that would have significant terrestrial benefit? CAN HUMANS SURVIVE 1,000 DAYS Concepts for the Future Fairfield • 3 SPEAKERS: Can Humans Survive 1,000 Days in Space? 4:30 – 5:30 PM Salons E-F • 4 • CARL KIRKCONNELL, CASIS SCIENCE AND IN SPACE? THE IMPACT OF ISS The Impact of ISS One Year Missions TECHNOLOGY ADVISORY PANEL (MODERATOR) ONE YEAR MISSIONS 5:30 – 5:45 PM Conference Closing Remarks Salons E-F • 4 • JUD READY, ADJUNCT PROFESSOR, NASA has set a “horizon goal” of enabling the sustained SCHOOL OF MATERIALS SCIENCE AND ENGINEERING, presence of humans on Mars by the 2030s. Among the *SEE PAGES 16-18 FOR TECHNICAL BREAKOUT DESCRIPTIONS GEORGIA INSTITUTE OF TECHNOLOGY most compelling questions is, Can humans survive 1,000 • ALEXEI CHURILOV, SENIOR SCIENTIST, days in space? Currently the ISS hosts a growing multi- RADIATION MONITORING DEVICES, INC. faceted collection of exploration-based research focused • ALEKSANDAR OSTROGORSKY, PROFESSOR OF MECHANICAL AND on answering this key question. In addition, human activity MATERIALS ENGINEERING, ILLINOIS INSTITUTE OF TECHNOLOGY onboard the International Space Station is teaching us about ASTRONAUT KEYNOTE ADDRESS & LUNCH

habitation, life support, and crew training and interaction SUNITA WILLIAMS, NASA ASTRONAUT during long-duration missions. This panel will explore many of the research areas addressing the 1,000 Days question. Astronauts Sunita Williams and Karen Nyberg will join the ISS R&D Conference for a special SPEAKERS: luncheon presentation. Both Sunita and Karen have lived and worked on the International • JAMES REUTHER, DEPUTY ASSOCIATE ADMINISTRATOR Space Station and have been instrumental in expanding the breadth OF PROGRAMS FOR THE SPACE TECHNOLOGY MISSION of investigations conducted in space. These incredible explorers will DIRECTORATE, NASA (MODERATOR) recount their time in space and discuss the significant contributions • JEFFREY DAVIS, DIRECTOR, HUMAN HEALTH AND of space research to humanity’s scientific understanding. Join us PERFORMANCE (HHP), NASA JOHNSON SPACE CENTER for this special event and gain an insightful perspective on the • MARK SHELHAMER, CHIEF SCIENTIST, NASA HUMAN RESEARCH importance of the ISS. PROGRAM (HRP) • GEORGY KARABADZHAK, HEAD OF SPACE EXPLORATION KAREN NYBERG, NASA ASTRONAUT COMPLEX, RUSSIAN FEDERAL SPACE AGENCY • BOB BAGDIGIAN, CHIEF, ENVIRONMENTAL CONTROL AND LIFE SUPPORT DEVELOPMENT BRANCH, NASA MARSHALL SPACE FLIGHT CENTER JULY 7-9, 2015 » BOSTON 15 TUESDAY, JULY 7 WEDNESDAY, JULY 8 TECHNICAL BIOLOGICAL INSIGHTS IN SPACE DRUG DISCOVERY AND DELIVERY Development of Miniature Mechatronic Platform for The Cloud-Aerosol Transport System (CATS): Overview of Remotely Tunable Nano Channel Implant for Controlled BREAKOUT SESSIONS Chemical and Biological Experimentation Aboard ISS a New Earth Science Capability on ISS Drug Delivery JOSE AVENDANO, Florida Institute of Technology MATTHEW MCGILL, NASA Goddard Space Flight Center ALESSANDRO GRATTONI, Department of Nano medicine, Enabling Commercial Earth Imaging and Hosted Payloads Houston Methodist Research Institute from the ISS with the Teledyne MUSES Facility Self-Assembly in Biology and the Origin of Life (SABOL): OCO-3 on ISS: Overview of Science Objectives and Status Cancer Diagnostic & Therapeutic Applications Developed MARK WHORTON, Teledyne Brown Engineering An Investigation into Alzheimer’s ANNMARIE ELDERING, JPL/Caltech From Microencapsulation Experiments on ISS Applications for Reducing Complexity and Increasing SAMUEL DURRANCE, Florida Institute of Technology Flying on ISS: RapidScat DENNIS MORRISON, NuVue Therapeutics, Inc. ISS Utilization Effects of ISS Spaceflight on Mammalian Immune Function HOWARD EISEN, Jet Propulsion Laboratory, California Electrolytic Gas Evolution at Microgravity KIRK WOELLERT, NanoRacks LLC MILLIE HUGHES-FULFORD, University of California San Institute of Technology Francisco and Northern California Institute for Research Windows on Earth: Stunning Photographs of Earth by the LAURENCE ALBERTS, Cam Med LLC CREW RESEARCH AND PERFORMANCE and Education Astronauts have Great Value for Science and Education Technology for Growing High-quality Protein Crystal in the Applying Canonical Correlation Analysis with Multiple A Genomics and Synthetic Biology ISS Platform to DANIEL BARSTOW, TERC, Inc International Space Station Imputation to a NASA High Dimensional/Small-n Data Set: Understand Radiation Biology HIROAKI TANAKA, Borrowing Strength from Multivariate Dat ADVANCES IN COMMUNICATIONS Confocal Science Inc. COREY NISLOW, University of British Columbia, Dept. of Attempts to Crystallize the Huntingtin Protein on the ISS ROBERT PLOUTZ-SNYDER, USRA / NASA Pharmaceutical Sciences Optical Payload for Lasercomm Science (OPALS) GWEN OWENS, Caltech Canadian Space Agency Contribution to ISS Research Using Yeast Mutants in Microgravity to Identify Mechanisms Operations Results of Anti-Cancer Drugs MATTHEW ABRAHAMSON, Jet Propulsion Laboratory, PLANTS AND OMICS IN SPACE DENIS CHARLEBOIS, Canadian Space Agency California Institute of Technology TIMOTHY HAMMOND, Dept. Veteran Affairs, Duke Univ. Schl The Journey of the Garden of ETON AMO EXPRESS: A Command and Control Experiment for Med; G. Washington Schl. Med From Remote Terrestrial Networks to Deep Space Comm- Crew Autonomy Onboard the International Space Station MARYANN LILLITH ADIA BULAWA, Chicks in Space LIVING IN SPACE unications—Delay Tolerant Networking Provides a Solution HOWARD STETSON, Teledyne Brown Engineering Morphometric and GFP Reporter Gene Observations from SUZANNE DAVIDSON, The Boeing Company Using Ophthalmic Resistivity Index Response to Applied the CARA (Characterizing Arabidopsis Root Attractions) ISS Onboard Virtual Reality Trainer (VRT) Force for Noninvasive ICP Monitoring: In Vivo Animal and Haptics-2: Preparing ISS for Advanced real-time Tele- Spaceflight Experiment EVELYN MIRALLES, L-3/NASA JSC/AIAA Human Testing operation Experiments between Space and Ground ANNA-LISA PAUL, University of Florida Improving Astronaut Performance of JEFF HAWKS, University of Nebraska-Lincoln ANDRÉ SCHIELE , European Space Agency & Delft University Transcriptomics Reveal Mechanical, ROS and Hypoxic ISS National Lab Research Tasks Using of Technology ® Development of A Plethysmography System to Assess the Stress Responses in Arabidopsis Grown in the the Juxtopia Context-Aware Mobile Physiology of Venous Return In Microgravity Conditions On the Development of Automated Orbit, Access and Microgravity Environment Mixed Reality Assistive Device Pointing Control for the SCAN Test Bed (CAMMRAD) ANGELO TAIBI, University of Ferrara SARAH SWANSON, University of Wisconsin - Madison DEAN SCHRAGE, Zin Technologies Inc. JAYFUS DOSWELL, Juxtopia Expression Profile Of Oxidative Stress Genes In Spaceflight GeneLab: “Omics” Data Systems for Translational Space TK6 Lymphoblast Experiences and Lessons Learned from Developing and Biology Research TECHNOLOGY Manifesting an Applied Research Project to the ISS DEVELOPMENTS ON ISS JINGHE MAO, Tougaloo College KAUSHIK CHAKRAVARTY, Logyx LLC MARTIN TSCHIRSCHWIT, JAMSS America, Inc (JAI) Highlights of United States Immune Modulation and Radiation Measurements for ISS/ Utilization of ISS for the Microbial Characterization: Department of Defense Spacex-3 Flight Radiation Experiment in Support of the SENSORS AND COMPONENTS Genomics, Proteomics, Pharmacomics, and Agronomics Space Test Program use of the UR-1 Project in Normal Human Lymphocytes Under Microgravity Some Assembly Required: Why and How the Amine International Space Station ALAMELU SUNDARESAN, Texas Southern University Swingbed Was Launched in Pieces Then Assembled On KASTHURI VENKATESWARAN, NASA - Jet Propulsion Laboratory JAMES MCLEROY, DoD Space Test Program Orbit for the First Time, Integrated, Tested, and Oper Bone Loss during Spaceflight: Available Models and DEVELOPING COMMERCIAL Lessons Learned from the RINGS Project: Counter-Measures MICHAEL WHITTEN, JETS contract, JSC CAPABILITIES AND SERVICES an Experiment Planning and Design JONATHAN MORRIS, Department of Evaluation of the Xsens Force Shoe On ISS Development Status of the Terrestrial Return Vehicle Framework for New Technology Advancement Orthopedic Surgery, Montefiore Medical ANDREA HANSON, NASA Johnson Space Center for Science and Engineering Sample Return from the ANDREW HILTON, MIT Center, Bronx, NY, USA International Space Station Wireless Leak Detector for International Space Station Robonaut 2: Building a Robot on the International LOOKING AT EARTH (WiLD-ISS) STEVE ALTEMUS, Intuitive Machines Space Station Limb-imaging Ionospheric ALI ABEDI, University of Maine ICE Cubes: International Commercial Experiment Cubes, CHARLES JOYCE, NASA/Oceaneering Space Systems and Thermospheric Extreme- Establishing a Fast-track, Low-cost Service for Small Integrated Ultra-Wideband Tracking and Carbon ultraviolet Spectrograph Experiments to the ISS Astrobee: Developing a Free Flying Robot for the Dioxide Sensing System Design for International (LITES) on the ISS International Space Station Space Station Applications TOM HOPPENBROUWERS, Space Applications Services NV/SA SUSANNA FINN, University of CHRIS PROVENCHER, SGT Inc. Enabling LEO Research for Commercial and Non- Massachusetts Lowell JIANJUN (DAVID) NI, MRI/JETS/NASA Johnson Space Center Government users, and Facilitating a Robust Commercial Technology Development on ISS for Satellite Servicing Using Small Business Funding to Develop a Universal Market on the International Space Station (ISS) and Exploration Battery Charger for ISS REGGIE SPIVEY, Teledyne Brown Engineering BENJAMIN REED, NASA Goddard Space Flight Center JOHN MERK, Aurora Flight Sciences JULY 7-9, 2015 » BOSTON 17

TECHNICAL PREMIER BREAKOUT SESSIONS MATERIALS MANUFACTURING SPONSORS AND FUNCTION IN SPACE 3-D Printed Ultem 9085 Onboard the ISS PLATINUM THURSDAY, JULY 9 SEAN CHRISTENSEN, NASA SPHERES Made In Space Update on Additive Manufacturing aboard ISS SPACE BIOLOGY TOOLS BOEING: Boeing is the world’s largest aerospace company and the leading manufacturer HASTI AFSARIFARD, Business Development Associate of commercial jetliners and defense, space and security systems. A top U.S. exporter, the NASA’s Rodent Research Project on ISS: Validation of company supports airlines and U.S. and allied government customers in 150 countries. Boeing a New Platform for Conducting Biomedical and Basic ISS experiment for Study Friction and Wear products and tailored services include commercial and military aircraft, satellites, weapons, Research into the Consequences of Long Duration MARAT BRONOVETS, Institute for Problems in Mechanics electronic and defense systems, launch systems, advanced information and communication systems, and performance-based logistics and training. RUTH GLOBUS, NASA Ames Research Center Ras Labs-CASIS-ISS Synthetic Muscle Experiment: Flight-Tested Hardware Options Currently Available to Resistance to Radiation GOLD Support Fruit Fly Science Missions on ISS LENORE RASMUSSEN, Ras Labs MATTHEW LERA, NASA Ames Research Center/FILMSS Effect of 1.5 Years of Ram, Wake, Zenith and Nadir Space ORBITAL ATK: A global leader in aerospace and defense technologies, Orbital ATK designs, builds and delivers space, defense and aviation-related systems to customers around the world, WetLab-2: Providing Quantitative PCR Capabilities on ISS Exposure on the Tensile Properties of Teflon both as a prime contractor and also as a merchant supplier. The company’s main products MACARENA PARRA, Logyx LLC/Ames Research Center KIM DE GROH, NASA Glenn Research Center include launch vehicles and related propulsion systems; satellites and associated components and services; composite aerospace structures; tactical missiles, subsystems and defense The ISS Bone Densitometer for Rodent Research STEM PROGRAMS AND PROCESSES electronics; and precision weapons, armament systems and ammunition. JOHN VELLINGER, Techshot, Inc. Columbus Eye, Earth Guardian, Flying Classroom, Aktion 42 and Others: DLR’s Educational Activities during Zero Gravity Mass Measurement Device SILVER Alexander Gerst’s Mission to the ISS JOHN WETZEL, Orbital Technologies Corporation (ORBITEC) JOHANNES WEPPLER, German Aerospace Center (DLR) FEDEX: With its diverse portfolio of transportation, e-commerce, and business solutions, CELL AND MICROBIOLOGY IN SPACE Does Vermicomposting in a Cosed System Have the Same FedEx Corporation’s air, ground and sea networks cover more than 220 countries and OSTEO-4: Osteocytes and Mechanotransduction Efficiency in Microgravity as it Does on Earth? territories. FedEx Space Solutions provides shipping and packaging solutions for the satellite and space-driven technology industries, maximizing efficiency and safeguarding the delivery of PAOLA DIVIETI PAJEVIC, Boston University and SHANNA ATZMILLER, Bell Middle School critical assets for remote sensing, scientific and biomedical research, defense applications and Massachusetts General Hospital Centaurus Micro-Gravitational Experiment: A Framework microspace platforms and communications. Microgravity Enhances Osteoclast Activity Revealed by for Student-Led Experiments Aboard the ISS, as Presented 2 Months-rearing of Medaka Fish in ISS from a Student’s Perspective SILVER AKIRA KUDO, Tokyo Institute of Technology BRYAN MCCARTY, Centaurus High School & CASIS SIERRA NEVADA CORPORATION: In 25 years of experience, Sierra Nevada Conversion of Adipogenic Mesenchymal Stem Cells into NanoRacks LLC NanoLabs a Proven Low Cost Method to Corporation’s Space Systems has participated in over 400 successful space missions through Mature Cardiac Myocytes Get Student Microgravity Science Experiments into Space the delivery of over 4,000 systems, subsystems and components. The company’s four lines of CLIFFORD DACSO, Baylor College of Medicine and Back Within the School Year innovative, responsive and cost-effective products range from spacecraft actuators to hybrid DAN SALDANA, Valley Christian High School of San Jose rocket technologies, and from Internet-controlled microsatellites to the winged and piloted MicroRNA Expression Profile and DNA Damage Response orbital commercial spacecraft Dream Chaser®. in Cultured Human Fibroblasts in Space CONCEPTS FOR THE FUTURE HONGLU WU, NASA Johnson Space Center The “Bishop” Airlock: NanoRacks Commercial Space SILVER Characterizing Phenotypic and Gene Expression Changes Station Airlock A joint venture of Lockheed Martin and The Boeing in E. coli Challenged with Antibiotics during Spaceflight MICHAEL LEWIS, NanoRacks, LLC UNITED LAUNCH ALLIANCE: Company, the United Launch Alliance provides reliable, cost-efficient space launch services for LUIS ZEA, University of Colorado, Boulder NASA’s XHab Project: Design of an Inflatable Airlock the U.S. government—including the Department of Defense, NASA and other organizations. Prototype for Astronaut EVA The company has successfully delivered more than 90 satellites to orbit, providing critical DARREN HITT, capabilities for troops in the field, aiding meteorologists in tracking severe weather, enabling University of Vermont GPS navigation, and unlocking the mysteries of our solar system. ISS Demonstrations for the Commercialization of Low Earth Orbit Enterprises MEDIA KENT KATTERHEINRICH, Flexible Composites Inc. Exploring New Lagrangian Cyclers to Enhance Science: SPACENEWS: Dedicated to covering the business and politics of the global space industry, Communications with CubeSat Technology SpaceNews is a privately owned multimedia company headquartered in Alexandria, Virginia, with staff and correspondents around the world. SpaceNews was founded in 1989 as a weekly PEDRO LLANOS, Embry-Riddle Aeronautical University business-to-business newspaper, which remains a must-read for thousands of government and Magnetic Reconnection Propulsion: The ISS as a Test Bed industry space professionals. for Advanced Deep-Space Technology DAVID CHESNY, Florida Institute of Technology JULY 7-9, 2015 » BOSTON 19 MARKETPLACE AIRBUS DS SPACE SYSTEMS, INC.: Airbus DS Space Systems has a distinguished history of providing external payload carriers, payload integration services, software SPONSORS engineering, and flight simulation / training solutions to NASA and the international aerospace community. ADSH has evolved into a trusted supplier of commercial hardware and services designed to help unlock the commercial and scientific potential of Low Earth Orbit and beyond.

KENTUCKY SPACE/SPACE TANGO: Focused primarily on the entrepreneurial space marketplace, Space Tango’s capabilities and experience involve CubeSat class and BIOSERVE SPACE TECHNOLOGIES: Located at the University of Colorado other micro-satellites and subsystems, satellite ground operations, space platform design Boulder, BioServe Space Technologies has over 28 years of experience designing, building and testing and development of novel technology and experiments for the International and flying microgravity life science research and hardware on over 50 space flight missions. Space Station (ISS). Space Tango is committed to a highly collaborative business strategy BioServe has a full suite of space flight certified hardware available for use by its customers and works closely with a number of other companies, universities and organizations. and partners. Past partners include pharmaceutical and biotechnology companies as well as universities and NASA-funded researchers.

LOCKHEED MARTIN: Headquartered in Bethesda, Md., Lockheed Martin is a global security and aerospace company that employs about 112,000 people worldwide and is The Boy Scouts of America BOY SCOUTS OF AMERICA NATIONAL FOUNDATION: principally engaged in the research, design, development, manufacture, integration and National Foundation is responsible for developing the relationships, long-term partnerships and sustainment of advanced technology systems, products and services. financial support needed to create better futures for the 2.5 million young men and women in scouting. The Boy Scouts are proud to be working to improve STEM literacy and career awareness through our sponsorship of innovative strategies like the CASIS ISS Design Challenge.

MASSACHUSETTS LIFE SCIENCES CENTER: The Massachusetts Life Sciences Center (MLSC) is an investment agency that supports life sciences innovation, CSS-DYNAMAC: Since 1995, CSS-Dynamac has provided science support to over research, development and commercialization. Charged with implementing a ten-year, 170 payloads bound for space. Located at Space Florida’s Space Life Sciences Laboratory, $1-billion, state-funded investment initiative designed to create jobs and support advances CSS-Dynamac provides services and laboratory space to support the entire research cycle. that improve health and well-being, the MLSC offers the nation’s most comprehensive set Services include preflight science activities, science-to-hardware integration, preparation of incentives and collaborative programs targeted to the life sciences ecosystem. for installation of research into launch vehicle, ground control activities, and post-flight activities for experiments returning from spaceflight. NANORACKS: NanoRacks, formed in 2009, provides commercial hardware and services for the U.S. National Laboratory onboard the International Space Station (ISS) via a Space Act ECLIPTIC ENTERPRISES CORPORATION: Ecliptic Enterprises Corporation is the Agreement with NASA. The company’s customer base—which includes ESA, DLR, NASA, Planet Labs, world’s leading supplier of rugged video systems for use on rockets, spacecraft and in other Urthecast, Space Florida, NCESSE, and Virgin Galactic—has propelled NanoRacks into a leadership extreme environments. Founded in 2001, Ecliptic applies its extensive experience in the design, position in understanding the emerging commercial market for Low Earth Orbit utilization. analysis, assembly, testing and operations of aerospace systems and subsystems. From the big picture to the details, Ecliptic knows its business.

TECHSHOT, INC.: For more than 25 years, Techshot has been developing complex payloads for microgravity research professionals. Our devices have flown aboard parabolic- ELI LILLY: Founded in 1876 by Colonel Eli Lilly, a man committed to creating high- flight aircraft, sub-orbital rockets, space shuttles, the SpaceX Dragon and the International quality medicines that meet real needs, Eli Lilly is still passionate about making life Space Station. From experiment ideation, to hardware development, to crew training and better for individuals, communities, and the world around us. The company employs mission support, Techshot is your one-stop spaceflight integration/implementation partner. approximately 41,000 Lilly employees worldwide, and more than 8,000 are engaged in research and development at facilities located in six countries.

TELEDYNE BROWN ENGINEERING: Teledyne Brown has more than 30 years of expertise in the entire payload operations and physical and analytical integration process— from FISH & RICHARDSON: One of the world’s premier intellectual property and litigation concept development to hardware fabrication, software development, and on-orbit science firms, Fish & Richardson works with clients to protect and enforce intellectual property rights operations. Areas of technical expertise and services include physical and analytical payload globally. Our office in Munich, Germany serves clients’ needs throughout Europe, and our integration, hardware development and manufacturing, on-orbit operations and remote Earth extensive network of relationships with counsel around the world ensures we are ready to sensing from the MUSES platform. provide comprehensive IP services in virtually any jurisdiction.

ZIN TECHNOLOGIES: With over 60 years of experience, ZIN Technologies has engineered, designed, analyzed, fabricated, verified and operated over 225 NASA HNu PHOTONICS: Incorporated in 2006, HNu Photonics is a cutting-edge science space flight payloads, using numerous launch vehicles and logging thousands of hours of and technology company based in Maui, Hawaii. The focus of the company is renewable operations in space. ZIN provides services in systems design, development, engineering energy, defense photonics, specialized optics, and medical imaging technologies, with and integration, testing and evaluation, modeling and simulation for the full life-cycle of commercial, scientific and military applications. HNu has made major breakthroughs aerospace hardware and software. in solar energy generation and medical technology, including a revolutionary form of microscopy with broad clinical, scientific and even forensic applications.

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