TABLE OF CONTENTS

MISSION STATEMENT 1 DIRECTOR’S STATEMENT 2 ORGANIZATIONAL CHART 4 CENTER FOR SCIENCE AND ENGINEERING PARTNERSHIPS 5 CENTER FOR SCIENTIFIC COMPUTING 12 FACULTY USERS 14 MULTI-USER FACILITIES 15 MICROFLUIDICS LAB 17 BIOLOGICAL NANOSTRUCTURES LABORATORY 19 NANOSTRUCTURES CLEANROOM FACILITY 21 LOW TEMPERATURE CHARACTERIZATION FACILITY 22 SMALL BUSINESS INCUBATOR PROGRAM 23 CHALLENGE GRANT PROGRAM 26 ELINGS PRIZE FELLOWSHIP PROGRAM 49 FUNDING SUMMARY 2016-2017 53 AWARD ADMINISTRATION 54 FACILITY MAPS 76 77 Building Location Map 77 PUBLICATIONS 78 2016-2017 STATISTICAL SUMMARY 88 ADVISORY COMMITTEE AND STAFFING 90 Advisory Committee 90 Administrative Staff 90 Center for Science and Engineering Partnership Staff 90 Technical Staff 90 PRINCIPAL INVESTIGATORS 91 MISSION STATEMENT

MISSION STATEMENT The mission of the NanoSystems Institute is to foster knowledge and understanding of by serving as a center for scientific research breakthroughs where disciplinary boundaries disappear. This overarching objective stems from its partnership with UCLA; its role as a Governor Gray Davis Institute for Science and Innovation (ISI); as well as a valuation of nanoscale science as the vanguard of scientific and economic progress. UCSB / UCLA Partnership The California NanoSystems Institute (CNSI) is an integrated research facility with locations at UCSB and UCLA. CNSI members represent a multi-disciplinary team of some of the world's preeminent scientists from the life and physical sciences, engineering, and medicine. The work at CNSI-UCSB focuses on three targeted areas of nanosystems-related research: Biotechnology; Energy Efficiency; and Information Technology. By combining the resources, expertise, and facilities, CNSI endeavors to encourage university collaboration with industry and to enable the rapid commercialization of discoveries in nanoscience and nanotechnology. Visionary Investment As a Governor Gray Davis Institute for Science and Innovation (ISI), CNSI builds on a visionary investment in future education, research, and technological resources, seeded and supported by the State of California. CNSI also builds upon the existing collaborative strengths of its on- campus participants, and seeks new alliances with industry, universities, and national laboratories. The vision of the CNSI is to establish a coherent and distinctive organization that serves California and the nation, embedded on the UCSB and UCLA campuses. The CNSI is a world-class intellectual and physical environment—a collaborative center that will generate ideas, discoveries, and the talent that will continue to fuel innovation in nanosystems. Science and the Economy In the 21st century, both science and the economy will require technological discoveries in the control of nanometer scale structure and functions, where the top-down approach of electronics manufacture converges with the bottom-up assembly principles of biology. CNSI has chosen to focus on the scientific and technological richness of new advances made possible by the integration of engineered nanoscale building blocks into complex systems. Major Breakthroughs CNSI anticipates the centrality of nanoscale technologies as the major source of scientific breakthroughs in this new millennium. An understanding of how to manipulate, control, and manufacture at the nanometer scale will drive innovation at the highest levels. The rewards of such understanding lie in the formation of engineered materials with exceptional strength, elasticity, sensitivity, and intelligence. Control of materials at the nanometer scale will ensure the creation of compact, complex, and multifunctional systems at the macro-scale, dramatically augmenting the current capabilities of communication, computation, medical therapy, and environmental remediation.

CNSI Annual Report - 2016-2017 Fiscal Year 1

DIRECTOR’S STATEMENT

DIRECTOR’S STATEMENT

CNSI continues to work with campus-wide stakeholders to leverage the combined strengths of nanoscience and nanotechnology research at UC Santa Barbara to foster a world-leading nexus of research, education, and translational activities. To increase campus-wide engagement and collaboration, the CNSI leadership has devoted considerable effort during the 2016-2017 academic year to identify and develop strategic initiatives in (1) Research, (2) Shared Resources and Facilities, (3) Entrepreneurship, and (4) Education, Outreach, and Workforce Development.

Research The long standing strength of CNSI in grant management and proposal submission has significantly impacted numerous key initiatives within the broad Science and Engineering effort at UCSB. During FY 2016-2017, 44 extramural awards representing over $25 million in funding was administered, impacting over 70 Principal Investigators. To further catalyze collaborative research and the development of junior faculty, CNSI has continued to refine and invest in the Challenge Grants program which is a long-term partnership with Dr. Meredith Murr and the UCSB Office of Research. The ultimate aim is to incubate large-scale research centers within CNSI and to allow campus researchers to compete on a national stage for these high profile, multi-PI grants. Unlike traditional seed-research funds, the Challenge Grant programs focus on creating collaborative interactions and preliminary results which allow faculty teams to be well positioned for highly competitive, high impact funding such as NSF Science and Technology Centers, NIH U01s, or DOE Energy Frontier Research Centers. During the past year we launched the Challenge Grant New Partnerships Program which is designed to fill a significant need at UCSB for catalyzing new interdisciplinary collaborations that may require preliminary data needed to apply for a collaborative research grant. These awards support direct costs of up to $50,000 over a period of 12 months, and successful teams can apply for a follow-up Program Development Challenge Grant. Four initial New Partnership Awards involving 8 PIs (4 of whom are Assistant Professors) were initiated this year and we have continued to invest in more mature collaborative projects through the award of three new Program Development Grants in 2017. To illustrate the success of the overall Challenge Grant scheme in FY 2016-17, PIs submitted 15 funding proposals to government agencies and foundations for a requested total of over $35 million with 4 proposals being funded this year including a $1.625 million grant from the American Diabetes Association and a $500,000 grant from the Juvenille Diabetes Research Foundation.

Shared Resources and Facilities CNSI continues to provide mission-critical, open-access shared facilities for UCSB and the wider California research community. Success in funding applications and significant investment in CNSI Annual Report - 2016-2017 Fiscal Year 2

DIRECTOR’S STATEMENT

new equipment has allowed all CNSI facilities to increase their impact across all of campus. Over 10 major pieces of new equipment were installed this year with particular highlights being two successful MRI proposals leading to the acquisition of a state-of-the-art high-performance computer cluster and a unique RAMAN microscope system, the latter being the first such system at UCSB. The combined shared resources at CNSI have served more than 700 users from over 20 departments and ORUs resulting in 100+ publications citing support from CNSI facilities. The Center for Scientific Computing (jointly operated with the Materials Research Laboratory) continues to be the de facto high performance computing center at UCSB and is providing an expanding leadership role on campus and within the greater UC system. Entrepreneurship

The most important entrepreneurial activities within CNSI this year were focused on implementing California legislation AB2664 and the expansion of dedicated wet-laboratory and office space for UCSB affiliated start-up companies. AB2664 will allow the relocation of these activities to a larger space in Elings Hall, installation of additional fume hoods, and the construction of supporting office space. Construction is expected to be completed by the end of 2017. As part of AB2664, CNSI will also create a Makerspace multi-user facility with funds being leveraged to purchase a suite of equipment that will enable teams to rapidly create prototype products. In 2017, CNSI again partnered with TMP to sponsor three prizes in the New Venture Competition. In addition to the Virgil Elings Prize of $5,000, CNSI sponsored a $5,000 People’s Choice award, and the top technology-driven company in the competition was offered a 3- month incubator membership. Education, Outreach, and Workforce Development The Center for Science and Engineering Partnerships (CSEP) continues to have a major effect on numerous single-PI and multi-PI research programs at UCSB. By offering scientific training through undergraduate research opportunities, scholarships, bridge programs, industry internships, and mentoring/networking initiatives, CSEP engaged with ~10,000 students this year and provides professional preparation and career transition for more than 2000 UCSB undergraduate, PhD and postdoctoral research trainees each year. The CNSI Education and Outreach programs mentor and train a diverse group of young scientists to become leaders in academia, industry, or government while extending University impact by building meaningful relationships with Californians beyond the UC system. This can be easily recognized by the breadth of CSEP engagements - 120+ faculty from 25 campus departments coupled with 170+ industry representatives. In total, 17 education initiatives and 13 evaluation and tracking projects are encompassed in the CSEP portfolio, while partnering with faculty on 37 new proposals to Federal and State Agencies, and Private Foundations occurred this year. Additionally, CSEP-led components of the SEED SB project funded by AB2664 include a needs assessment project to collect feedback from the Tri-Counties entrepreneur community, a stories project creating advice films by entrepreneurs, and more programming to meet the needs of current and future entrepreneurs on our campus.

CNSI Annual Report - 2016-2017 Fiscal Year 3

ORGANIZATIONAL CHART

ORGANIZATIONAL CHART

Craig Hawker Director CNSI Advisory CommiYee Javier Read de Alaniz, Megan Valen:ne, Stephen Wilson Associate Directors

Tal Margalith Holly Woo Execu:ve Director of Assistant Director Technology

Center for Science and Engineering Financial Services Partnerships (CSEP) Administra:ve Services Research Services

Eva Deloa M. Ofelia Aguirre Jessica Ajao Dave Bothman Financial Manager Director Contracts and Grants Microfluidics Lab

Theodore Thomas Financial Analyst Lee Sawyer Wendy Ibsen Marissa Guillen Cleanroom Associate Director Admin. Analyst

Daniel Daniels Lubi Lenaburg Purchasing Coordinator Jen Smith Evalua:on and Assessment Manager Jessica Henry Biological Events & Visitors/Admin Nanostructures Lab Analyst Arica Lubin Lynne Leininger Professional Financial Assistant Development Bob Hanson Sonya Perez Building Manager Academic Personnel Maria Napoli Community College

Paul Weakliem Center for Scien:fic Ellie Sciaky Compu:ng Evalua:on Coordinator

Stephanie Mendes Undergraduate Research

Samantha Davis Undergraduate Research

CNSI Annual Report - 2016-2017 Fiscal Year 4

CENTER FOR SCIENCE AND

ENGINEERING PARTNERSHIPS

CENTER FOR SCIENCE AND ENGINEERING PARTNERSHIPS

INTRODUCTION The Center for Science and Engineering Partnerships (CSEP) represents a one-stop resource for many UCSB scientists and engineers for the design, facilitation and evaluation of broader impact and workforce development components for national centers and individual PI research/education proposals to government agencies. CSEP also provides infrastructure for consultation and resources to expand current, and develop new, STEM initiatives with a priority on integrating programs that aim to broaden the diversity of students who pursue a STEM career. The current CSEP portfolio of education programs and services are managed by a staff of seven Academic Coordinators and one administrative assistant. From July 1, 2016 to June 30, 2017, CSEP provided educational programming for 9,600+ K-12 and community members, 30+ community college students, 730+ UCSB undergraduate and 1,400+ graduate students and postdoctoral scholars. These initiatives engaged 120+ faculty from 25 campus departments and 170+ industry representatives to serve as directors, instructors, mentors, speakers and advocates for 17 education initiatives and 13 evaluation and tracking projects.

Consultation with Faculty CSEP’s strength is our ability to build strategic partnerships that leverage and strengthen our infrastructure, with a focus on shared benefits that also increase visibility and value for our partners. Our extensive network and expertise enable us to serve as an effective institutional resource, providing faculty and research institutes a broader reach through well-established program models and assessment tools. By maintaining a diverse and robust suite of programs that align with timely institutional and funding agency goals, we are able to respond to the needs of new projects that require the ability to adapt existing infrastructure to novel ideas. A special focus on evaluation offers campus partners a distinctive mechanism to meet funding agency requirements for data collection and analysis about short and longer-term broader impacts of science, technology, engineering, and mathematics (STEM) partnerships. Over the last reporting period CSEP provided varying levels of support to faculty on 37 proposals to Federal and State Agencies, and Private Foundations. Please see included table following the “Communication and Calendar” section.

Highlights of CSEP partnerships with Faculty partners Following are several examples from the current reporting period that highlight new curriculum and training paradigms, along with novel outreach components, that engage faculty, researchers, students and community members alike.

K12 and Community Programming CSEP’s School for Scientific Thought (SST) teamed up with the IEEE Photonics Society Chapter at UCSB to create a short course on the “Physics of lasers and light” taught during Fall 2016 and Winter 2017, by graduate student chapter members in Electrical & Computer Engineering: Eric Stanton, Philip Chan, Kareem Hamdy, Takako Hirokawa, Warren Jin, Victoria Rosborough. Overall, 40 students in grades 9-12 participated in this enrichment course from UCSB Partnership Schools and the local area. Graduate student instructors received training and mentoring in science communication and curriculum development. Funding for the course was through an IEEE Photonics Society award and the national Manufacturing USA initiative via AIM Photonics West Coast Headquarters at UCSB.

CNSI Annual Report - 2016-2017 Fiscal Year 5

CENTER FOR SCIENCE AND

ENGINEERING PARTNERSHIPS

The IEEE Photonics Society Chapter Outreach committee partnered with Industry Liason Demis John, 8th grade Science Teacher Marilyn Garza, and CSEP’s Family Ultimate Science Exploration (FUSE) to create a new program activity “Color Mixing” as part of the Manufacturing USA initiative. Over 1,500 8th grade students and their family members participating in this activity at 5 Santa Barbara County Junior High Schools. Graduate student volunteers received training in communicating science to the public. The activity was shared at the Optical Fiber Conference (OFC) in Los Angeles on March 31, 2017, along with a “Free space laser communications” lesson developed as part of the SST “Physics of lasers and light” course.

Program website: http://csep.cnsi.ucsb.edu/programs/fuse

Press Releases: The Current article and video: http://www.news.ucsb.edu/2016/017362/sharing-passion-science The Current article: http://www.news.ucsb.edu/2016/017410/girl-power Daily Nexus article: http://dailynexus.com/2016-11-28/inspiring-photonics- for-the-future/

The SST and FUSE projects are led by CSEP Associate Director Ms. Wendy Ibsen, with support from Professor John Bowers and AIM Photonics for the SST laser course and FUSE color activity as part of the national Manufacturing USA Photonics Initiative.

CNSI Annual Report - 2016-2017 Fiscal Year 6

CENTER FOR SCIENCE AND

ENGINEERING PARTNERSHIPS

PIPELINES The Problem-based Initiatives for Powerful Engagement and Learning In Naval Engineering and Science (PIPELINES) is a collaborative project of University of California Santa Barbara (UCSB) and the Naval Facilities Engineering Command Navy Engineering and Expeditionary Warfare Center (NAVFAC EXWC) at Port Hueneme. The PIPELINES program is an 8-week immersive experience, where teams of undergraduate students compete in finding the most innovative and effective design solutions to real- world Naval engineering and science design projects. Interns attend weekly meetings, special seminars, and sharpen their problem-solving and entrepreneurial skills through a course on Applied Creativity and Innovation.

Impact: A number of projects developed over the summer have laid the groundwork for further evaluation to be pursued by EXWC. This accomplishment is notable given the short (8-week) duration of the program. For instance, both the designs developed for “Design of a Boarding System for LARC-V A1/A2 Vehicles” and “NetZero CLUs: An Automated Solar Panel Cleaning System” will be implemented into a functional prototype for further operational evaluation. The decision-making tool developed as part of the project “Renewable Energy Integration Tool” will be included in the NAVFAC Microgrid Design and Reference Guide. Program website: http://pipelines-csep.cnsi.ucsb.edu/

PIPELINES is workforce development initiative led by CSEP’s Dr. Maria Napoli as project PI and faculty partners such as Bob York in the Technology Management Program (TMP) and Brad Paden in the Department of Mechanical Engineering at UCSB, along with NAVFAC EXWC at the Port Hueneme Naval Base.

CNSI Annual Report - 2016-2017 Fiscal Year 7

CENTER FOR SCIENCE AND

ENGINEERING PARTNERSHIPS

SEED SB SEED-SB is a new campus-wide initiative at UCSB designed to support innovation and entrepreneurship. It stems from a CA State "Innovation and Entrepreneurship Expansion" Initiative - AB2664 - that provided each UC campus with catalyst funds to bolster infrastructure that aids in launching new entrepreneurs and technologies. At UCSB this is translating into things such as the Technology Incubator and Maker Space at CNSI, TMP's Garage Incubator at the Mosher Alumni House, and proof of concept grants from Bren School and the Office of Technology and Industry Alliances. It's also supporting CSEP- led components that include a needs assessment project to collect feedback from local entrepreneurs, a stories project creating advice films by entrepreneurs, and more programming to meet the needs of current and future entrepreneurs on our campus.

Within the initiative, CSEP is leading a needs assessment project on the Tri-Counties entrepreneur community that, in partnership with CNSI, TMP, Bren, and the Office of Technology and Industry Alliances, is informing the implementation of expanded mentorship and professional development activities. CSEP is also focused on representing the diversity among entrepreneurs through short advice films, and increased networking and professional development opportunities for UCSB trainees. Winter and Spring 2017 quarter efforts resulted in 15+ entrepreneur assessment interviews, 3 advice films, and 6 events that served over 300 graduate students, postdocs, faculty and researchers at UCSB and included 26 entrepreneur and industry professionals. The programming was diverse and brought new discussions and partnerships to our campus community such as: STEAM (a.k.a. How to Combine Every Thing You Love and Call it Work) by Keri Kukral, Founder & CEO, RAW SCIENCE TV; and a series on the NSF I-Corps and Innovation Node-Los Angeles where NSF Program Director for I-Corps, Steve Konsek, informed the campus about the I-Corps funding opportunities, and IN-LA instructors, Melihe Taciroglu and Azar Nazeri, brought an intensive training workshop to potential I-Corps applicants at UCSB. The AB2664 funding is January 2017 to December 2019.

The SEED SB project is led by Dr. Tal Margalith at CNSI and Dave Adornetto at TMP, along with Sherylle Englander at TIA, Emily Cotter from Bren, CSEP Associate Director Dr. Arica Lubin and Evaluation Program Manager Dr. Lubella Lenaburg. CSEP resources leveraged include the Professional Development Series (PDS) for graduate students and postdocs, along with extensive evaluation expertise.

Art of Science

CNSI Annual Report - 2016-2017 Fiscal Year 8

CENTER FOR SCIENCE AND

ENGINEERING PARTNERSHIPS

In science, as in art, the practitioner pursues moments of discovery when observations become greater than the sum of their parts and begin to reveal an untold story. The Art of Science initiative recognizes the creative and experimental nature of science and challenges UCSB researchers to visually communicate the beauty inherent to scientific investigations. Visualizing these discoveries connects scientists, artists, and the community at large. The Art of Science initiative encourages researchers to express the joy of scientific discovery through aesthetics.

The 4th annual competition received 56 submissions from UCSB undergraduates, graduates, and postdoctoral researchers. There were over 6,000 votes cast throughout the community for the Art of Science Competition.

Program website: http://art-csep.cnsi.ucsb.edu/

Press Releases: Promotional Art of Science Video: https://youtu.be/EVI6ARQDfYE The Current article: http://www.news.ucsb.edu/2017/017794/you-are-so-beautiful Daily Nexus article: http://dailynexus.com/2017-04-20/research-discoveries-lead-to-art-of-science- competition/

Exhibitions: Santa Barbara Museum of Art (SBMA) - April 27-May 9, 2017 SBMA Artists Reception held April 27, 5:30-7PM https://www.facebook.com/events/117194558839550/ UCSB Library - July 28, 2017-January 25, 2018 https://events.ucsb.edu/event/art-of-science-2017/

The Art of Science is part of Professor Jon Schuller’s NSF CAREER award outreach component. This partnership leverages CSEP’s Professional Development Series (PDS) for graduate students and postdocs under the supervision of CSEP Associate Directors Dr. Arica Lubin and Ms. Wendy Ibsen.

CNSI Annual Report - 2016-2017 Fiscal Year 9

CENTER FOR SCIENCE AND

ENGINEERING PARTNERSHIPS

Evaluation Services Over the past decade, CSEP has served as a unique campus resource to help STEM faculty with the design and implementation of appropriate evaluation plans. Over the past 2 years, the demand for evaluation services has significantly increased, both in quantity and scope of projects with short 2-day projects to multi-year initiatives. Other universities have also sought services from CSEP, as we have developed a strong reputation among faculty partners.

To accommodate the dynamic and diverse evaluation needs of our campus and external partners, we have recently developed a recharge model for evaluation to simplify the process for all partners. This reporting period, CSEP Evaluation Services developed evaluation plans for 14 UCSB proposals that span small NSF AISL projects to the campus NSF MRSEC. Currently, we are evaluating 10 UCSB and 2 external projects that span multiple departments, center and partners, including the American Physical Society (APS) and the University of Washington.

Communication and Calendar CSEP has been building capacity to share events, promote activities, recruit participants, and build relationships through the use of social media. We promote current initiatives, as well as current and former student success. Currently, we are promoting the Art of Science exhibit on display at the UCSB Library through January 28, 2018. Please visit and join our various media outlets to learn more about our programming and participants.

Facebook: @CSEP.UCSB Twitter: @CSEP_UCSB Instagram: @csep_ucsb YouTube: https://www.youtube.com/user/UCSBcsep/playlists

For questions regarding our various media outlets, please contact CSEP Associate Director Ms. Wendy Ibsen.

CNSI Annual Report - 2016-2017 Fiscal Year 10

CENTER FOR SCIENCE AND

ENGINEERING PARTNERSHIPS

CSEP Program Development and Evaluation Support for Faculty July 1, 2016 to June 30, 2017

UCSB Proposals Funding Agency Program PI Outcome Service UCOP AB2664 Tal Margalith Funded Prog. dev., evaluation section, writing NSF AISL George Legrady Declined/asked to reapply Prog. dev. consulation and evaluation section writing NSF AISL Danielle Harlow Declined Evaluation section writing NSF NRT Susannah Scott Pending Evaluation section writing NSF NRT Barry Giesbrecht Pending Evaluation section writing NSF LSAMP BD Javier Read De Alaniz Funded Complete proposal DoD CRED Linda Petzold Pending Complete proposal NSF MRSEC Ram Seshadri Recommended for funding Evaluation section writing NIH ESTEEMED Karen Szumlinski Pending Complete proposal NSF REU John Bowers Declined Complete proposal NSF REU Gretchen Hofmann Funded Prog. dev. consulation and evaluation section writing NSF Tripods John Gilbert Declined Prog. dev. consultation and evaluation section writing USDA HIS Helene Gardner Pending Evaluation section writing USDA HIS Susannah Scott Pending Evaluation section writing DoD AIM-WFD John Bowers Funded Complete proposal DoD AIM-WFD John Bowers Funded Complete proposal DoD AIM-WFD John Bowers Pending Complete proposal Beckman Foundation Scholars Joel Rothman Pending Complete proposal NSF CAREER Yon Visell Pending Outreach component UCOP UC-HBCU Jon Schuller Pending Prog. dev. and evaluation consultation NSF CISE Mahnoosh Alizadeh Pending Broader impact component UCSB FOG grant Jennifer King NA Outreach partnership with CSEP NSF CCE STEM Glenn Beltz NA Outreach partnership with CSEP NSF CHS Yon Visell Declined Broader impact component NSF AAPF Miguel Daal/Ben Mazin Declined Prog. dev. consulation and outreach partnership NSF CHS Pradeep Sen Declined Broader impact component DoD HBCU/MSI Inst. Rolf Christoffersen NA Outreach partnership with CSEP UCOP UC-NL CRT Ania Jayich Declined Prog. dev. consultation and partnership UCOP UC-NL CRT David Weld Declined Prog. dev. consultation and partnership UCOP UC-HBCU Jerry Gibson Pending Prog. dev. consultation and partnership NIH IMSD Karen Szumlinski Pending Proposal data support NSF CSDM-B Javier Read De Alaniz Declined Broader impact component

Off Campus Proposals NSF Expeditions U Virginia/UCSB (Strukov) Pending Prog. dev. and evaluation section writing NSF INCLUDES AG-Bell Declined Evaluation section writing NSF PIRE Univ. of Pittsburg Funded Prog. dev. consultation and evaluation section writing NSF CCI U Michigan/UCSB (Read de Alaniz) Pending Prog. dev (ie Art of Science expansion to U. Michigan and Princeton) NSF IUSE American Physical Society Funded Evaluation section writing NA - information not available

CNSI Annual Report - 2016-2017 Fiscal Year 11

CENTER FOR SCIENTIFIC

COMPUTING

CENTER FOR SCIENTIFIC COMPUTING

The mission of the CSC is to enable teaching and research through the use of high performance computing.

Computing Equipment CSC operates the campus available 1,700 core cluster Knot with over 200 active users. CSC also operates two condo clusters (guild, braid) where PI’s buy nodes and CSC provides infrastructure and professional system administration of the clusters. The current cluster is 124 nodes (over 2,200 cores).

Staff

CSC is formally composed of staff from:

• California NanoSystems Institute (CNSI) – Paul Weakliem • Materials Research Lab (MRL) – Fuzzy Rogers • Enterprise Technology Services (ETS) – Burak Himmetoglu

Several staff from other units are involved on an informal basis.

CNSI Annual Report - 2016-2017 Fiscal Year 12

CENTER FOR SCIENTIFIC

COMPUTING

FY 2016/2017 overview

This past year was marked by continued growth in the condo cluster (from 104 to 124 compute nodes), and continued use of the now aging Knot (campus available) cluster. While in the first 6 months of 2017, there were 45 publications, not too far off the pace from the high of 104 in calendar year 2014. Since the formation of CSC, over 450 publications have acknowledged use of the facility, illustrating its impact on supporting campus research in a relatively short period of time. In addition, a number of advanced undergraduates have benefited from use of the system. CSC staff has continued to provide one on one and seminar style instruction on the use of the CSC systems and computational based research computing.

The condo clusters have continued to grow (from 104 to 124 compute nodes), including a purchase by a recently recruited COE faculty member.

Note that a table of these, and other, metrics is included in the ‘Facilities’ section. The CSC held a number of seminars and workshops, hosting software workshops, and several supercomputing workshops, including hosting the Scaling to the Petascale Institute, which was a national workshop with satellite locations around the world. There were only four satellite locations in California (Stanford, UCLA, LBNL, and UCSB). There were approximately four hundred participants worldwide, with fifteen UCSB researchers. In the fall quarter, we held a Fall Computing Series to introduce new users to the high-performance facilities available to UCSB researchers, both at CSC and the national centers.

CSC strongly believes in student development, and over the summer, CSC was one of the sponsors of the ‘GS^3’ (Graduate Simulations Seminar Series’) which is organized by graduate students in science and engineering for them to share their research with fellow students. This series encourages the students to present, learn, and interact with fellow students, furthering UCSB’s cross-disciplinary environment.

UCSB Principal Investigators whose groups have used more than 10,000 core*hours of time during the period July 2016-June 2017 on CSC clusters (campus available Knot cluster, and/or Condo clusters)

CNSI Annual Report - 2016-2017 Fiscal Year 13

CENTER FOR SCIENTIFIC

COMPUTING

FACULTY USERS

PI Primary Dept/ORU PI Primary Dept/ORU Atzberger Math Levi Materials Aue McFarland Chem. Engr Balents KITP Melack EEMB Bamieh Mech Engr Metiu Chemistry Bazan CPOS Mezic Mech Engr Beyerlein Mech Engr Nguyen CPOS Bibilashvili Physics Oakley EEMB Birnir Math Oono EEMB Bowers, M Chemistry Peters Chem. Engr Briggs EEMB Pollock Materials Brown Chemistry Proulx EEMB Brzezinski EEMB Rose ECE Campas Mech Engr Rupert Econ Chabinyc Materials Schuller ECE Chen Chemistry Segalman Chem. Engr Craig Physics Sen ECE DenBaars SSLEEC Seshadri MRL deVries, M Chemistry Shea Chemistry deVries, T Geog Shell Chem. Engr Ding Geog Sherwin Physics Espinoza Math Shraiman KITP Fisher Physics Srednicki Physics Ford Chemistry Steigerwald Econ Fredrickson MCCAM Stemmer MRL Funk ERI Turner, T EEMB Garcia-Cervera Math VanderVen Materials Hegarty Psych VandeWalle Materials Hofmann EEMB Wang PSTAT Husak ERI Wang, Y PSTAT Jayich Physics Weld Physics Ji Geology Xu Physics Kim MATP Yang CS Krintz CS Zhang, L Chemistry Leal Chem. Engr Zok Materials

CNSI Annual Report - 2016-2017 Fiscal Year 14

MULTI-USER FACILITIES

MULTI-USER FACILITIES

CNSI is a world-class hub for research ranging from bioengineering to physics to and chemistry. Our mission is to create a collaborative, closely integrated, and strongly interactive environment to advance nanosystems research and education and bring scientific and technological innovation into the economy and society.

CNSI Technical Staff (Left to Right): P. Weakliem, J. Smith, B. Himmetoglu, T. Margalith, B. Hanson, D. Bothman, L. Sawyer

One aspect of this mission is to provide researchers the tools and equipment necessary for them to conduct advanced research. CNSI manages a number of multi-user facilities (MUFs), overseen by lab managers experienced in operating shared facilities and able to train and guide research in key focus areas:

• Microfluidics Lab: Providing equipment and expertise in fabricating microfluidic devices.

• Biological Nanostructures Lab: Providing instrumentation and capability at the interface of life science and engineering, the capabilities include tissue culture and next-generation sequencing.

• Nanostructures Cleanroom Facility: Tool sets and processes complement research in the chemical and biological nanostructures labs, with additional capabilities in materials synthesis and photomask fabrication.

• Low Temperature Characterization Facility: Special purpose scientific apparatus and associated electronic components for measurement of superconducting quantum bits.

• The Center for Scientific Computing (jointly operated with the Materials Research Laboratory): Formed to promote the effective use of High Performance Computing in the research environment, the CSC provides a broad range of resources for campus researchers, including operation of the campus available 1,700 core cluster Knot.

CNSI Annual Report - 2016-2017 Fiscal Year 15

MULTI-USER FACILITIES

Additionally, Elings Hall houses multi-user facilities managed by the Materials Department, the Media Arts and Technology Department, and the Materials Research Laboratory:

• Allosphere Research Facility (MAT Department): Enabling the visualization, sonofication and exploration of complex multi-dimensional data to enable progress in a number of critical areas of science and engineering.

• Microscopy and Microanalysis Facility (Materials Department): Instruments for materials characterization include transmission electron microscopes, focused ion beam microscopes, field-emission scanning electron microscopes, atomic force microscopes, an atom probe field ion microscope and dedicated XPS and SIMS systems.

• Spectroscopy Facility (Materials Research Laboratory): The Spectroscopy facility of MRL is the home to the state-of-the-art magnetic resonance instruments in solution NMR, solid-state NMR, MRI, Rheo-NMR, PFG-Diffusion, DNP-NMR, and EPR.

• X-Ray Diffraction Facility (Materials Research Laboratory): Provides state-of-the-art x-ray diffraction tools for characterizing structural properties of a wide range of materials including metals and composites, polymers and biological materials, and electronic and optoelectronic materials.

METRICS

In the past year, these multi-user facilities have served more than 700 users from over 20 departments and ORUs:

MUF Int. Users PI Groups Dept’s/ORUs Ext. Groups Microfluidics 93 31 9 5 BNL 195 45 15 10 NCF 114 36 8 9 LTCF 18 1 1 1 CSC 290 75 24 0

CNSI Annual Report - 2016-2017 Fiscal Year 16

MULTI-USER FACILITIES

MICROFLUIDICS LAB

The CNSI Microfluidics Lab is a campus-wide resource for researchers who use custom-made microfluidic devices in their work. The lab currently has trained users from mechanical, electrical and chemical engineering; chemistry, biology, materials, physics, MRL, SSLEEC, and Media Arts and Technology. The lab also supports off-campus users who learn about the lab from on-campus colleagues. CNSI created the lab to support two distinct groups of researchers: experienced device fabricators who benefit from having a comprehensive tool set in one location, but just as importantly we want to serve researchers who have creative ideas about using novel microfluidic devices, but don’t have much experience making them. The lab also supports undergraduates working on course-related projects.

The lab has tools for making several different classes of microfluidic devices: cast PDMS, directly machined (laser and mill) polymer devices, and thermally molded polymer flow channels. CNC drills and mills are available for machining ports and vias in Silicon and glass using diamond tooling, and aligned punches are available for creating ports in polymers. The Microfluidic Lab also has tools for surface activation using ozone and vapor deposition of silanes. The lab supports custom-made bond aligning tools and microscopes for inspection. In partnership with the CNSI Cleanroom we also provide mask and mold making services – both etched Silicon and SU-8 molds are available. A high-resolution 3D printer and CNC mill are available for making molds, fixtures and experimental apparatus. The lab also has a full suite of optical microscopes for inspection.

The lab is housed in class 100,000 cleanroom space in Elings Hall, room 3430 and is available 24/7 via card key access. The lab is adjacent to the CNSI cleanroom and Biological Nanostructures Lab enabling multi-disciplinary research opportunities.

CNSI Annual Report - 2016-2017 Fiscal Year 17

MULTI-USER FACILITIES

FY 2016-17 Overview:

49 Training classes were conducted in the CNSI Microfluidics Lab last year. The Microfluidics Lab also supports undergraduate and graduate instruction. This year we supported about 20 students the following courses: ME189A,B,C, ME158, ME225MV, ECE189, ME/ECE141B.

Several new tools were added to the lab this year including:

• Diamond dicing saw

• Pressure casting chamber

• Droplet microfluidics work station

• Custom 3D printer for polymer characterization

• High-speed camera microscopy workstation

Lab users recognized Microfluidics Lab support for the research in 21 papers and talks (see Publications section).

CNSI Annual Report - 2016-2017 Fiscal Year 18

MULTI-USER FACILITIES

BIOLOGICAL NANOSTRUCTURES LABORATORY

The mission of the Biological Nanostructures Laboratory (BNL) is to provide high-value instruments and resources to support and enhance interdisciplinary research at the interface of life science and engineering. The instruments and capabilities in the BNL are organized into four different cores: Genetics, Analytical, Cell Culture, and Autoclave Cores. As a core research facility, the BNL serves the UC Santa Barbara research community and several local for-profit companies, including the CNSI Incubator labs.

The BNL Genetics Core includes two Illumina NGS sequencers, equipment for NGS library preparation, DNA/RNA sample preparation, and a Bio-Rad Droplet Digital PCR. The Analytical Core includes instruments used for nanoparticle characterization, fluorescence and absorbance measurements, as well as other commonly used instruments in molecular biology, including PCR thermal cyclers, equipment for bacterial cell culture, and BSL-2 lab space.

The BNL Cell Culture Core (previously known as the Tissue Culture Core) houses equipment used for mammalian cell culture. The BNL provides cell culture as a staff service for non-life science-trained researchers; this service has greatly expanded the type of experiments that can be done by non-life scientists at UCSB. The Autoclave Core consists of two steam sterilizers. The Autoclave Core supports the BNL Cell Culture and Analytical Cores by providing necessary sterilization and biohazardous waste decontamination, and provides an important decontamination role for research labs in Elings Hall and surrounding buildings, as it houses the only autoclave near these locations.

A full listing of Genetics Core, Analytical Core, and Cell Culture Core instruments can be found on the BNL webpage.

Metrics:

FY 2016-17 Genetics Analytical Cell Culture Total Number of researchers 55 167 21 195 Number of PI groups 15 38 8 45 Number of departments / ORUs 9 14 4 15 Number of external companies 1 8 1 10

CNSI Annual Report - 2016-2017 Fiscal Year 19

MULTI-USER FACILITIES

FY 2016-17 Overview: In FY 16/17, the BNL was used by 195 UCSB researchers from 45 research groups and 15 departments on campus. The total user base of the BNL was similar to the previous fiscal year, with an increase in Analytical Core and Cell Culture Core users, and a slight decrease in the number of Genetics Core users.

The BNL Genetics Core added an Illumina MiSeq DNA sequencer in FY 16/17, expanding the types of the sequencing projects the BNL can accommodate. In particular, the MiSeq is the most commonly used sequencer for metagenomics studies, due to its wide range of sequencing kits available. Also, added to the Genetics Core was a wet bench space for researchers to use for the preparation of Next Generation Sequencing (NGS) DNA libraries.

8 publications were published with data generated using the BNL facility (see Publications section).

Other Activities In early 2017, the BNL implemented a new scheduling and recharge software, Facilities Billing Software (FBS). FBS serves to centralize the BNL user database, instrument training and scheduling, tracking instrument and consumables use, and recharges and billing.

The BNL hosted several instrumentation seminars, bringing in speakers from vendors GE Biosciences, Illumina, Agilent, Takara/Clontech, and Bio-Rad. These informational seminars were very well received, and are useful to promote BNL instruments and capabilities to a wider audience. These seminars also serve to help determine the most desired instruments to bring into the lab, with the goal of providing the greatest benefit to the UCSB research community.

CNSI Annual Report - 2016-2017 Fiscal Year 20

MULTI-USER FACILITIES

NANOSTRUCTURES CLEANROOM FACILITY

The Nanofabrication Cleanroom Facility (NCF) is a shared recharge facility that houses a mix of traditional semi-conductor processing equipment, specialty deposition tools and a Material Synthesis Sore (MSC) that houses various types of crystal growth furnaces. Besides providing access to process equipment, the NCF offers mask writing and microfluidic master mold fabrication services that cater to the university’s research community as well as some external academic and non-academic entities.

Metrics:

FY 2016-17 NCF MSC Masks Molds Number of researchers 31 17 65 1 Number of PI groups 13 4 30 1 Number of departments / ORUs 8 3 8 1 Number of external companies/groups 4 0 9 7

FY 2016-17 Overview: The past year has seen the integration of a JSW AFTY solid- source electron cyclotron resonance (ECR) plasma deposition system, a Filmetrics reflectance, transmittance, and film thickness measurement tool, and a Tystar wet and dry oxidation tube furnace system. The NCF user base, in combination with the MSC user base, has seen a 31% increase from the previous fiscal year. This user base increase is mainly attributed to the new tools listed above. For the 2017-2018 fiscal year, the NCF will be adding a new triple Raman spectrometer which will help to diversify the user base by adding users from disciplines that the facility’s current tool set does not typically attract.

CNSI Annual Report - 2016-2017 Fiscal Year 21

MULTI-USER FACILITIES

LOW TEMPERATURE CHARACTERIZATION FACILITY

The Low Temperature Characterization Facility (LTCF) houses special-purpose scientific apparatus for measurement of superconducting quantum bits and their associated electronic components. The systems have been specially configured for wiring access and electronic instrumentation to perform specific high-fidelity and low-noise measurements of quantum devices. These systems are aimed at enhancing our knowledge of measuring quantum devices, giving students a broader understanding of the measurements and capabilities of these devices.

The LTCF offers the following equipment and services:

1) 2 wet dilution refrigerators: These cryostats require the use of the liquid nitrogen and liquid helium cryogens, whose cost is significant and included in the recharge rate. The refrigerators have a unique capability of allowing a large number of microwave connections to the mixing chamber plate. Included in the systems are electronics for the control of the superconducting qubits, as well as the appropriate interface software.

2) 1 dry dilution refrigerator: This cryostat has a closed cycle cryo-cooler, so that no liquid cryogens are need during operation. The capabilities and electronics are the same as for the wet dilution refrigerator.

3) 4 adiabatic demagnetization refrigerators: These cryostats have a base temperature about 3 times larger than the dilution refrigerators, and only stay cold for about 12 hours before needing to be recharged. They are primarily used to test materials and functionality for the superconducting devices. They are smaller and have reduced wiring capabilities, as appropriate for a test system. Included are control electronics and microwave measurements for vector network analysis.

4) 1 molecular beam epitaxy vacuum system: This vacuum system allows cleaning and growth of Aluminum films on a silicon or sapphire wafer at 1-10 torr vacuum conditions. The system has a load-lock entry system allowing wafers to be transferred into high vacuum in less than 6 hours. The wafer can be heated up to 1000C for cleaning and annealing purposes. The system has an Oxygen plasma cleaning system, an electron beam evaporator, quartz crystal monitor, and RHEED for surface analysis.

5) 1 wire bonder: This system allows wire bonds to be made from a chip to an external chip mount. It is set up for aluminum wires, as appropriate for superconducting systems, and has a deep access wedge for use in typical mounts

CNSI Annual Report - 2016-2017 Fiscal Year 22

SMALL BUSINESS INCUBATOR

PROGRAM

SMALL BUSINESS INCUBATOR PROGRAM

The CNSI Technology Incubator, in operation since May 2015, is designed to promote CNSI’s mission of bringing scientific and technological innovation into the economy and society and enable greater ties between the CNSI academic community and industry. The Incubator is physically located in Elings Hall, in close proximity to the CNSI Core Labs and the Materials Characterization Facilities, and is part of the broader UCSB Innovation and Entrepreneurship ecosystem that includes the Technology and Industrial Alliances (TIA) office, the Technology Management Program (TMP), the Eco-Entrepreneurship program at the Bren School, and the Center for Science and Engineering Partnerships (CSEP). Laboratory space, including chemical fume hoods, as well as separate office space, is available for lease by local technology-focused start-ups. The CNSI Incubator is one of the only wet-lab incubators on the Central Coast, and the only one of its type in Santa Barbara. The current facilities can accommodate 4-6 companies at full occupancy.

Metrics:

FY 2016-17 Active Companies 4 Companies leasing lab space 2 Companies leasing desk space 4 Alumni Companies 1

FY 2016-17 Update:

• In the past fiscal year, has expanded the benefits of Incubator membership by partnering with the Materials Research Laboratory (MRL) and the UCSB Nanofabrication Facility to offer qualified incubator companies access at reduced recharge rates. This complements similar access to the CNSI Multi-user Facilities – the microfluidics laboratory, the Nanostructures Cleanroom Facility, and the Biological Nanostructures Facility – and alleviates the need to add dedicated equipment to the Incubator while promoting the growth of UCSB’s facilities to the benefit of both UCSB researchers and entrepreneurs.

• In 2017, CNSI again partnered with TMP to sponsor three prizes to the finalists in the New Venture Competition. In addition to the Virgil Elings Prize of $5,000, CNSI sponsored a $5,000 People’s Choice award, and the top technology-driven company in the competition was offered a 3-month incubator membership.

CNSI Annual Report - 2016-2017 Fiscal Year 23

SMALL BUSINESS INCUBATOR

PROGRAM

• In March, the CNSI Incubator again co-sponsored (with the office of Technology and Industry Alliances) the Startup Village at the South Coast Innovation Awards hosted by the Pacific Coast Business Times. The Village showcased 30 promising spinout companies from Cal Poly San Luis Obispo, California Lutheran University, and UCSB, and attracted investors from the Central Coast and Los Angeles.

• As part of California legislation AB2664 – promoting the growth of infrastructure supporting innovation and entrepreneurship at each UC campus – CNSI is significantly expanding the footprint of the incubator facility, through relocation to a larger space in Elings Hall, installation of additional fume hoods, and the construction of supporting office space. Construction is expected to complete in the Fall of 2017, and the new incubator should be able to accommodate 6-8 companies.

• Also as part of AB2664, CNSI will create a Makerspace multi-user facility. Funds will be leveraged to purchase a suite of equipment that will enable teams to rapidly create prototype products. The Makerspace facility will complement capabilities in the CNSI microfluidics laboratory, the campus machine shops, and the undergraduate design labs, and will be set up as a recharge facility open to both campus and industrial users.

CNSI Annual Report - 2016-2017 Fiscal Year 24

SMALL BUSINESS INCUBATOR

PROGRAM

Active Member Companies:

Milo Sensors is developing the first, wearable, blood alcohol sensor. Team Milo won the CNSI Incubator prize for the top technology-driven company in the 2015 TMP NVC. Milo Sensors has seen tremendous Milo Sensors growth this year, rapidly expanding team and operations. Milo Sensors Joined CNSI Incubator: has leveraged the CNSI Incubator for wet lab & office space and access August 2015 to instrumentation to accelerate product development. In just the past 6 months, their first commercial product, PROOF™, a Fitbit-like wearable for reading blood alcohol content, has been featured in TechCrunch, Mashable, Digital Trends and BBC, and completely sold- out of units on Indiegogo.

NEXT’s mission is to transform windows and glass facades into producers of low-cost, on-suite, renewable energy for buildings. NEXT windows can help dramatically reduce the carbon footprint of buildings. NEXT is leasing a desk in the Incubator office in order to NEXT Energy better interact with the UCSB research community. Joined CNSI Incubator: April 2016 The overarching goal for Laxmi Therapeutic Devices, Inc. is to develop a painless wearable continuous glucose monitor (CGM) that can be developed quickly, manufactured cost-effectively, and does not require calibration. Started in June 2016, the company has developed a novel method with which to sample glucose, and has relied on the CNSI incubator space for the development of an enzyme-based chemistry with which to sample unprecedented volumes of glucose accurately. Laxmi Therapeutics The company plans to build prototypes and perform feasibility testing Joined CNSI Incubator: in conjunction with the William Sansum Diabetes Center within the September 2016 next year.

bioProtonics magnetic resonance-based diagnostic paradigm, µTexture, dramatically extends the resolution limits of magnetic resonance imaging of biologic textures, enabling early stage clinical diagnoses. Over this past year, bioProtonics advanced its magnetic-resonance-- based technology, demonstrating ability to diagnose early stage disease bioProtonics in targeted pathologies. The company filed several patents, adding to Joined CNSI Incubator: its IP base. Towards validation of efficacy in an expanding range of January 2017 diseases, they have set up collaborations with key opinion leaders in various fields of engineering and medicine. The collaboration at UCSB with Jean Carlson’s Complex Systems group (http://web.physics.ucsb.edu/~complex/) has yielded much valuable information towards diagnostic optimization and determination of diagnostic sensitivity.

CNSI Annual Report - 2016-2017 Fiscal Year 25

CHALLENGE GRANT PROGRAM

CHALLENGE GRANT PROGRAM

Overview:

In support of the CNSI mission to foster interdisciplinary research across scientific disciplines, the CNSI Challenge Grants provide funding to promote the initiation of new large-scale and high-impact collaborations by CNSI faculty. These high-risk Challenge Grants are meant to:

§ Help UCSB faculty initiate and strengthen partnerships with academia and industry. § Increase flexibility and responsiveness to new research directions and opportunities. § Develop the next generation of scientific leaders at UCSB. § Incubate large multi-PI centers and programs within CNSI.

This year, the Challenge Grant program offered two funding mechanisms:

1) Program Development As with previous Challenge Grant rounds, these grants focus on enabling teams to strategically position themselves to compete for large center-scale funding. These awards are very flexible and may be used for a variety of purposes ranging from travel (to foster partnerships with institutions in academia or industry) to teaching relief (to provide time for multi-PI center proposal planning and preparation). These awards support direct costs of up to $50,000 over a period of 12 months for a maximum of $100,000 over two years.

2) New Partnerships These grants are focused on catalyzing new interdisciplinary collaborations within UCSB that may require a few key experiments to provide the preliminary data needed to apply for a collaborative research grant. We define new partnerships to be collaborations with no prior joint publications. These awards support direct costs of up to $50,000 over a period of 12 months, and successful teams can apply for a follow-up Program Development Challenge Grant.

In the past year, 2 calls for proposals have been issued and 7 projects have been funded out of a pool of 12 applications (3 Program Development Grants and 4 New Partnership Grants). Proposals were evaluated by a committee according to the following criteria: § Capabilities of the proposed team. § Plan for initiation and strengthening of partnerships. § Scientific and technical merit. § Potential for larger-scale funding / likelihood for long-term impact §

In the next year, we anticipate 2 additional funding rounds to initiate new Challenge Grant projects at UCSB.

CNSI Annual Report - 2016-2017 Fiscal Year 26

CHALLENGE GRANT PROGRAM

Metrics:

As of 6/30/17, there are 15 active grant programs (11 Program Development Grants and 4 New Partnership Grants). 4 programs ended in FY 2016-17.

FY 2016-17

Participants 50

Departments 11

Early-career faculty 7

External collaborators 11

Proposals submitted by CG teams 15

Proposed funding $35,958,336

Awards granted 4

Awarded funding $2,194,199

In FY 2016-17, Challenge Grant awardees submitted 15 funding proposals to government agencies and foundations for a requested total of $35,958,336. In this fiscal year, 4 proposals have been funded – Sumita Pennathur was awarded grants from the American Diabetes Association, the Juvenile Diabetes Research Foundation, and Angstrom Designs (STTR subaward), and Michelle O’Malley received a grant from the Air Force Research Laboratory.

CNSI Annual Report - 2016-2017 Fiscal Year 27

CHALLENGE GRANT PROGRAM

FY 2016-2017 ACTIVE GRANTS:

PROGRAM DEVELOPMENT GRANTS (New Programs for this Fiscal Year, represented in bold below)

• Engineering Well-Tailored Sensors and Actuators for Synthetic Materials • Seeding the Southern California Electrochemical Energy Storage Alliance • Bio-inspired High-Performance Information Processing • Next-Generation Computational Methods in Ship Hydrodynamics • Growing the California Institute for Quantum Emulation • Quantum Interfaces • Center for Adaptive Network Dynamics (CANDy) • Reconfigurable Photonic and Electronic Materials • Center for Recovering Chemical Resources and Energy from Waste Streams - NEW • Bio-Building Blocks for Advanced Materials (BBAM) - NEW • Center for Formulated, Functional Goos - NEW

NEW PARTNERSHIPS GRANTS

(New Programs for this Fiscal Year, represented in bold below)

• Large-scale Chip-Integrated Quantum Optic - NEW o Daniel Blumenthal and Ania Jayich

• Identifying and Characterizing Novel Un-Cultivatable Microbial Species Using Single-cell Genomics - NEW o Siddharth Dey and Michelle O’Malley

• Quantum Information and Energy: An Emerging Materials Nexus - NEW o Ram Seshadri and Kunal Mukherjee

• Organic Electronic Devices for Tactile Sensing in Soft Electronic Applications - NEW o Yon Visell and Thuc-Quyen Nguyen

CNSI Annual Report - 2016-2017 Fiscal Year 28

CHALLENGE GRANT PROGRAM

FY 2016-17 Update on Program Development Grants: Project: Bio-inspired High-Performance Information Processing

Start Date: February 1, 2015 PI: Dmitri Strukov, Professor of Electrical and Computer Engineering, UCSB Co-PIs: Yuan Xie, Professor of Electrical and Computer Engineering, UCSB; Konstantin Likharev, Professor of Physics and Neuroscience, Stony Brook University. Goal: Pursue a center focused on the fabrication and simulation of an artificial neural network using novel devices (memristors)

Synopsis: Building Artificial Neural Networks (ANNs) capable of matching the performance and functionality of biological counterparts in information processing remains one of the last grand challenges in computing. Bridging the performance gap between biology and today’s computers is especially timely given current technological trends, such as the exponentially growing sensor- and computer-generated data, and the emergence of new applications relying on such data, such as biomimetics and robotics. This project tackles this challenge in two parallel approaches. The first is the development of major components of hybrid circuits, such as memristors; their integration with conventional (CMOS) technology; and demonstration of hybrid-circuit-based ANNs. The second path focuses on understanding information processing of biological neural networks and replicating it in simulations.

Team Development: CRISP – Center for Research on Intelligent Storage and Processing-in-memory

East Coast Team (Kevin Skadron, Director) West Coast Team (Yuan Xie, Co-Director) UVA: Kevin Skadron UCSB: Yuan Xie UVA: Mircea Stan UCSB: Dmitri Strukov UVA: Samira Khan UCLA: Jason Cong Cornell: José Martínez UCLA: Song-Chun Zhu Cornell: Zhiru Zhang UCSC: Jishen Zhao PSU: Vijay Narayanan UCSD: Tajana Rosing PSU: Anand Sivasubramaniam UCSD: Steve Swanson Wisconsin: Jignesh Patel UCSD: Yuanyuan Zhou Wisconsin: Jing Li UCSD: Rob Knight Wisconsin: Kevin Eliceiri UW: Luis Ceze

Grant Applications: • NSF Expeditions in Computing, “Center for Nanoelectronic Neuromorphic Computation (CNNC)”, submitted January 18, 2017; proposal currently under consideration • Center for Research on Intelligent Storage and Processing-in-memory (CRISP) proposal submitted to SRC JUMP program on June 28, 2017

CNSI Annual Report - 2016-2017 Fiscal Year 29

CHALLENGE GRANT PROGRAM

Project: Engineering Well-Tailored Sensors and Actuators for Synthetic Materials

Start Date: April 1, 2015 PI: Javier Read de Alaniz, Assistant Professor of Chemistry and Biochemistry Co-PIs: Joseph Hooper, Assistant Professor of Physics, Naval Postgraduate School; Luciano F. Boesel, Group Leader, Empa: Swiss Federal Laboratories for Materials Science and Technology Goal: Build new collaborations to engineer “smart” polymers with the capability to sense their environment and to respond to that external stimulus via an active control mechanism

Synopsis: Materials of the future will require the capability to sense their environment and to respond to external stimuli via an active control mechanism (materials that mimic living systems and respond to their environment in order to repair themselves is one of the DOE’s Grand Challenges). Such functional materials have been made possible by the development of stimuli-responsive compounds that can be incorporated into polymers, and can subsequently be controlled by pH, light, electricity, or heat. Despite progress, reliability gaps in stimuli-responsive compounds such as poor stability under UV or oxygen, present a serious impediment to the design and development of new smart materials. The goal of this program is to design, study, and develop new stimuli-responsive systems based on the novel class of thermo- and photo-chromic material recently developed at UCSB. Potential applications range from fundamental studies to applied chemistry, from the visualizing and mapping of stress on everyday polymeric material to the development of transdermal drug delivery systems with adaptive properties.

Key Technical Achievements:

• Developed a modular method to access Donor-Acceptor-Stenhouse-Adduct (DASA)-polymer conjugates • Demonstrated their potential applications in rewritable data storage

CNSI Annual Report - 2016-2017 Fiscal Year 30

CHALLENGE GRANT PROGRAM

Team Development:

• Presented at MURI incubator on “Materials for Optomechanical Actuation”. This was sponsored by the Program Officers (Peter Morrison and Antti Makinen) for MURI Topic 20 and 21. • Established a MURI Team with Christopher Bardeen (UC Riverside), Todd Martinez (Stanford), Peter Palffy Muhoray (Kent University), Kaushik Bhattacharya (Caltech), Ryan Hayward (UMass Amherst). The overarching goal of this work is to use light to make mechanical work using photomechanical materials. • Established a MURI Team with Natalie Stingelin (Georgia Tech), Rachel Segalman (UCSB), Alberto Salleo (Stanford), Andrew Spakowitz (Stanford) and Christopher Ober (Cornell). The overarching goal of this work is to develop a Center for Responsive Multifunctional Super-Structured Materials Based on Hierarchical Assembled Polymer Architectures. • Pending grant application will be establishing a new collaboration with Megan Valentine.

Publications: • “Visible light-responsive DASA-polymer conjugates” ACS Macro Lett. 2017, 6, 738–742. One of the journal’s Top 20 most downloaded articles for the previous 30 days.

Grant Applications: • Submitted ICB grant (UCSB) with Megan Valentine “DASA-based photochromic materials for load-bearing applications: Emulating natures design light-addressable actuators. Under review • Submitted MURI proposal white paper for Topic 21 “Advanced Optical Materials that Create Force from Light,“ with Ryan Hayward (PI, UMass Amherst), Christopher Bardeen (Co-PI, UC Riverside), Todd Martinez (Co-PI, Stanford), Peter Palffy Muhoray (Co-PI, Kent University), Kaushik Bhattacharya (Co-PI, Caltech). Under review • Submitted MURI proposal white paper for Topic 20 “Materials for Smart Multifunctional Superstructures,” with Natalie Stingelin (PI; Georgia Tech), Rachel Segalman (Co-PI, UCSB), Alberto Salleo (Co-PI; Stanford), Andrew Spakowitz (Co-PI, Stanford), Christopher Ober (Co-PI, Cornell). Under review

CNSI Annual Report - 2016-2017 Fiscal Year 31

CHALLENGE GRANT PROGRAM

Project: Seeding the Southern California Electrochemical Energy Storage Alliance

Start Date: April 1, 2015 PIs: Ram Seshadri, Professor of Materials, UCSB; Anton Van der Ven, Professor of Materials, UCSB

Goal: Pool current expertise across SoCal to develop novel battery technology, positioning UCSB as a new research hub.

Synopsis: Energy storage is a research area whose time has come—particularly in California. Rapidly-expanding companies like Maxwell (the world’s leading supercapacitor company) and Tesla Motors are already based in California. In addition, Governor Brown’s pledge to have California generate 50% of its electrical power from renewables by 2030 suggests a huge and imminent need for stationary electrochemical storage. Despite widespread and untapped expertise at UCSB, there are currently no multi-PI grants at UCSB on the theme of electrochemical energy storage. Similarly, CNSI-UCLA and UCSD have battery electrochemistry experts who do not yet collaborate with the materials synthesis, characterization, and modeling expertise currently at UCSB. Through a series of workshops and student exchange grants, this program aims to coordinate the broader energy storage expertise across UCSB and neighboring universities by creating the Southern California Electrochemical Energy Storage Alliance, with an emphasis on novel electrode and electrolyte materials, and to establish multi-PI groups ready to pursue the next round of UCOP, DOE, and NSF funding calls. An industrial consortium modeled on UCSB’s Solid State Lighting and Energy Electronics Center is also a potential and reachable goal.

Key Technical Achievements: The team has developed (collaboration with Fred Wudl and Craig Hawker) a highly reversible polymer- based system for energy storage. A manuscript is in preparation. Data associated with this system is presented below.

CNSI Annual Report - 2016-2017 Fiscal Year 32

CHALLENGE GRANT PROGRAM

(a) Cyclic voltammetry of the new polymeric cathode material from 3.2 V to 0.75 V at a sweep rate of 0.1 mV/s. (b) Galvanostatic cycling with potential limitation (GCPL) at a rate of C/10 from 3.0V to 1.0V shown for 200 cycles. (c) Capacity for each cycle (charge and discharge) from GCPL increases through cycle 100 and maintains 150 mAh/g through 200 cycles. The error bar at cycle 100 represents the distribution of capacities observed over 10 different cells. (d) Coulombic efficiency, defined as charge divided by discharge capacity, hovers around 100% for all 200 cycles.

Team Development: The team has added Professor Sri Narayan (USC Chemistry) to the team and will soon have Dr. Kimberly See (Caltech, Chemistry) on as well. The next 1-day meeting is scheduled for October 24th.

Publications: • M. B. Preefer, B. Oschmann, C. J. Hawker, R. Seshadri, and F. Wudl, Crosslinked disulfide with high sulfur content mitigates polysulfide shuttle, yielding stable cycling in Li–S Cells (in preparation). • M. M. Butala, V. V. T. Doan-Nguyen, A. Lehner, C. Goebel, M. A. Lumley, S. Arnon, K. Wiaderek, O. Borkiewicz, K. Chapman, P. Chupas, M. Balasubramanian, and R. Seshadri, Local structure studies reveal the origin of capacity fade in the Li–CoS2 system (submitted). • M. M.Butala, M. Mayo, V. V. T. Doan-Nguyen, M. A. Lumley, C. Goebel, K. M. Wiaderek, O. J. Borkiewicz, K. W. Chapman, P. J. Chupas, M. Balasubramanian, G. Laurita, S. Britto, A. J. Morris, C. P. Grey, and R. Seshadri, Local structure evolution and modes of charge storage in secondary Li–FeS2 cells, Chem. Mater. 29 (2017) 3070–3082.

Grant Applications: The team is working with Brent Melot and Sri Narayan (USC) to submit an NSF-CCI grant in the next few months. An application with Toyota Research was not successful.

CNSI Annual Report - 2016-2017 Fiscal Year 33

CHALLENGE GRANT PROGRAM

Project: Next-Generation Computational Methods in Ship Hydrodynamics

Start Date: February 1, 2016 PIs: Frederic Gibou, Professor of Mechanical Engineering, UCSB; Paolo Luzzatto-Fegiz, Professor of Mechanical Engineering, UCSB

Goal: Assemble an expert team to successfully compete for an upcoming ONR MURI call for research on understanding the intricacies of ship movement through water

Synopsis: An improved understanding of ship hydrodynamics, including the mechanics of air entrainment and bubble wake, is critical to the US Navy. For example, bubble wake is the main source of ship vulnerability since a vessel can easily be located via satellite from its wake alone. Bubble formation is a complex phenomenon and an example of nanoscale dynamics influencing macroscale behaviors. The Office of Naval Research has recognized that without the development and validation of next-generation predictive computational methods, the understanding of multiscale phenomena relevant to ship hydrodynamics will remain elusive. Current modeling and computation strategies can take up to six months to execute. Prof. Gibou’s research is geared towards strategies that can be done in a matter of hours for complex geometries. Prof. Luzzatto-Fegiz’s work in experimental and theoretical fluid dynamics will be leveraged to validate the computations. The opportunities in the MURI call did not match the PIs’ expectations, and as such each PI participated in a separate, non-competing team. The PIs are actively looking at how to best redirect the CNSI Challenge Grant funding.

Key Technical Achievements: • The PIs have submitted to MURI opportunities – both funded. • The PIs have demonstrated the key role of surfactants in negating the effectiveness of superhydrophobic coatings for drag reduction on ship hulls. • The PIs are working to demonstrate the key features of a next-generation computational method for simulating surfactant-laden flows in naval applications.

Team Development: • Gibou’s team is led by K. Mahesh (U. ), and comprises: S. Ceccio (U. Michigan), J. Katz (J. Hopkins), P. M. Carrica (U. ), I. Siepmann (U. Minnesota), T. Sapsis (MIT), T. Colonius (Caltech). • Luzzatto-Fegiz’s team is led by I. Mezic (UCSB) and comprises S. Brunton (U. Washington), B. McKeon (Caltech), S. Revzen (U. Michigan), C. Rowley (Princeton), T. Sapsis (MIT), T. Colonius (Caltech) and Y. Kevrekidis (Princeton).

CNSI Annual Report - 2016-2017 Fiscal Year 34

CHALLENGE GRANT PROGRAM

Publications: • Reduced-order models for contaminated superhydrophobic surfaces for drag reduction. TEMPRANO-COLETO, LUZZATTO-FEGIZ & GIBOU. In progress. • Fully resolved simulations of contaminated superhydrophobic surfaces for drag reduction. TEMPRANO-COLETO, LUZZATTO-FEGIZ & GIBOU. In progress.

Grant Applications: • The PIs would like to discuss the possibility of refocusing the Grand Challenge grant towards submitting a proposal to the Keck foundation. The proposal would target the development of novel wind turbine designs, optimized for operating in large wind farms, which would seek order-of-magnitude increases in power output. This is an idea that is currently deemed too risky by other agencies (such as DoE), which are instead focusing on optimizing existing designs, but which the PIs believe would fit well within Keck’s portfolio.

CNSI Annual Report - 2016-2017 Fiscal Year 35

CHALLENGE GRANT PROGRAM

Project: Growing the California Institute for Quantum Emulation

Start Date: February 1, 2016 PI: David Weld, Professor of Physics, UCSB Co-PIs: Wes Campbell, Professor of Physics, UCLA; Sid Parameswaran, Professor of Physics, UCI; Congiun Wu, Professor of Physics, UCSD

Goal: Grow the scope of the California Institute for Quantum Emulation (CAIQuE) and to support its transition to a large-scale funded research collaboration.

Synopsis: Recently founded with support from a President’s Research Catalyst Award and matching funds from CNSI, the California Institute for Quantum Emulation (CAIQuE or IQE), aims to make the UC a world- leading consortium in the emerging field of quantum emulation. The institute draws together trapped- ion and ultracold-atom experimentalists from Berkeley, UCLA, UCSD, and UCSB with condensed-matter theorists from Berkeley, UCI, and UCSD. Scientifically, CAIQuE aims to develop a distinct UC brand of research in quantum emulation characterized by a deep integration of theoretical and experimental approaches. The initial scientific focus is on non-equilibrium quantum systems and topological bands. This program aims to grow the scope of the CAIQuE and to support its transition to a large-scale funded research collaboration. Seed funding from UCOP has already established a collaborative framework for IQE activities. The Challenge Grant funding will complement this through new activities such as an IQE summer school, an IQE Lectureship, and support for an IQE Postdoc, to raise the visibility of the IQE. The overarching goal is to build an ecosystem of the innovative research and educational activities that will form a part of a proposed Center, making a strong case for large-scale, long-term support, such as an MRPI Program grant, an NSF STC, a MURI, and possibly the new AFOSR quantum initiative.

Key Technical Achievements: • Implemented quantum chronoscope for simulation of ultrafast dynamics • Demonstrated interaction-driven stabilization of many-body Floquet state • Contributed to first observations of Floquet time crystals • Demonstrated coherent control of collective atomic spin oscillators

Left: Sub-cycle momentum response in quantum chronoscope. Right: Interaction-stabilized Floquet state in driven optical lattice.

CNSI Annual Report - 2016-2017 Fiscal Year 36

CHALLENGE GRANT PROGRAM

Team Development: • Andrea Young, UCSB • Andrew Jayich, UCSB • Dave Patterson, UCSB • Randy Hulet, Rice • Cory Dean, Columbia • Vincent Liu, Pitt • Jason Alicea, Caltech • Ehsan Khatami, San Jose State • Ben Lev, Stanford

Selected Publications: • Cavity-Assisted Measurement and Coherent Control of Collective Atomic Spin Oscillators, Kohler et al, Phys. Rev. Lett. 118, 63604 (2017). • Observation of a discrete time crystal, Zhang et al, Nature 543, 217 (2017). • Observation of discrete time-crystalline order in a disordered dipolar many-body system, Choi et al, Nature 543, 221 (2017). • Quantum Emulation of Extreme Non-equilibrium Phenomena with Trapped Atoms, Rajagopal et al, Ann. Phys. 529, 8 (2017). • Spectroscopy of a synthetic trapped ion qubit, Hucul et al. Accepted for publication in Phys. Rev. Lett. (2017). • Majorana surface modes of nodal topological pairings in spin-3/2 semi-metals, Yang et al, arXiv:1707.07261 (2017). • Interaction effects from the parity of N in SU(N) symmetric fermion lattice systems, Xu et al, arXiv:1707.01463 (2017).

Grant Applications: MURI: “Abelian Bridge to Non-Abelian Anyons in Ultracold Atoms and Graphene.” Awarded by the Army Research Office. Proposal and team development supported by this challenge grant.

CNSI Annual Report - 2016-2017 Fiscal Year 37

CHALLENGE GRANT PROGRAM

Project: Quantum Interfaces

Start Date: July 1, 2016 PIs: Ania Jayich, Professor of Physics, UCSB; David Weld, Professor of Physics, UCSB

Goal: Secure funding for a large-scale “Quantum Interfaces” program, with its hub at CNSI.

Synopsis: Quantum technologies promise to usher in major advances in fields ranging from information processing to medical imaging, and both governments and industry have recently intensified funding in the field. With the increased focus on quantum technologies has come a push for truly practical realizations. The quantum interfaces between elements (e.g. photons, atoms, solid-state spins, superconducting qubits) are the focus of the proposed research program. A central challenge of quantum technology is that the functionality enabled by interfaces is unavoidably accompanied by surface-mediated decoherence. Decoherence, in which a quantum element transitions into a classical state through uncontrolled interactions with the environment, is the fundamental obstacle to the realization of useful quantum technologies. A program of research focused directly on quantum interfaces has potential to enhance fundamental understanding of decoherence processes and surface physics while also unlocking new applications and abilities for hybrid quantum devices. Challenge Grant funding will be used to build up strength in key areas that will be crucial in making a large collaborative grant proposal competitive. A “New Directions in Quantum Interfaces” workshop will enable building connections and collaborations with the leaders in related fields. PIs will also leverage domestic and international travel funds to develop links with key theory collaborators and program managers, funding to help produce a strong record of preliminary collaborative results to support a final proposal, and teaching relief to provide time for the development of competitive collaborative proposals to federal agencies. Targeted funding sources include a MURI, a large-scale DARPA grant, an MRPI program grant, and possibly an anticipated federal initiative in quantum technologies.

Key Technical Achievements: • Initial operation of proof-of-concept apparatus (Figure 2). • Deposited lithium atoms on diamond with NV centers residing 5 nm below the surface. Calibrated lithium deposition rates.

a b

Figure 2: Quantum interfaces proof-of-concept apparatus. A) vacuum chamber mounted atop confocal microscope, b) Lithium atomic dispensers inside the vacuum chamber glowing as lithium is evaporated and deposited onto the diamond.

CNSI Annual Report - 2016-2017 Fiscal Year 38

CHALLENGE GRANT PROGRAM

Team Development: • Chris Lutz, IBM: expert on STM with adsorbed atoms, seminar Sep 14 • Nathalie de Leon, Princeton: diamond surface-mediated decoherence and surface preparation, seminar Aug 23 • Jeff Thompson, Princeton: atom-photon interfaces, seminar Aug 24 • Dan Blumenthal, UCSB: photonic interfaces • Vishal Agarwal, Indian Institute of Technology, DFT calculations of adsorbate atoms on diamond surfaces

A quantum interface between an NV center (white) below diamond

Industrial Connections: surface and several proximal • Presented Quantum Interfaces work to Samsung, who was interested in various quantum technology developments (Aug 17). Plan to submit a proposal to the Samsung GRO program after discussions with Samsung representatives attending.

Grant Applications: • CNSI Challenge Grant, Large-scale, chip-integrated quantum optic communications and interconnects, funded • Keck, Active Quantum Surfaces, under review at UCSB • White paper was submitted to the ARO/LPS Cross Quantum Technology Systems call. WP was rejected because it was beyond the scope of the program. However, ideas were encouraged to be submitted to the ARO’s basic research program, which we plan to do. • Planned October 11 visit to DC to visit program managers at AFOSR (Grace Metcalfe) and NSF (Alex Cronin).

CNSI Annual Report - 2016-2017 Fiscal Year 39

CHALLENGE GRANT PROGRAM

Project: Center for Adaptive Network Dynamics (CANDy)

Start Date: July 1, 2016 PI: Jean Carlson, Professor of Physics, UCSB Co-PIs: Megan Valentine, Professor of Mechanical Engineering, UCSB; Cheryl Briggs, Professor of Ecology, Evolution, and Marine Biology, UCSB; Yasamin Mostofi, Professor of Electrical and Computer Engineering, UCSB

Anchor member: Linda Petzold, Professor of Computer Science, UCSB

Goal: To develop the teaming, research thrusts, and infrastructure needed to successfully propose a new Center for Adaptive Network Dynamics.

Synopsis: The Challenge Grant will be leveraged to lay a foundation for a new UCSB Center for Adaptive Network Dynamics (CANDy) in preparation for the anticipated 2017 NSF STC funding call. Interplay and manipulation of dynamic mechanisms guiding adaptation within and between constituents in a population will serve as a unifying theme across three thrusts - Biological Systems, Ecological Systems, and Neurological Systems. Each thrust focuses on the role of dynamics and feedback operating over multiple length and time scales to control the behavior of complex, interconnected networks. Overarching themes include adaptive signaling, architectures and protocols for cyber-physical coordination and control, self-assembly, and resilience. In the long term, these discussions should seed breakthrough discoveries in health sciences, environmental protection, social response systems, threat management, and operations research.

The PIs plan to form teams of faculty from UCSB and partner institutions in order to develop the research, education, and infrastructure plan required of an STC proposal. The PIs anticipate applying for several MURI awards within the first year and to a large center-scale call (NSF STC) in Year 2.

Team Development: (1) Workshop on Adaptive Networks, UCSB, December 5-6, 2016 https://candy.cnsi.ucsb.edu/meeting/candy-workshop-uc-santa-barbara-december-2016

(2) Workshop on Adaptive Networks, Princeton, May 18-19, 2017 https://candy.cnsi.ucsb.edu/meeting/candy-workshop2

• Princeton was identified as a partner for the planned STC submission. • Princeton Leads: Naomi Leonard and Corina Tarnita. • Numerous skype meetings occurred during this project period, culminating in the Workshop on Adaptive Networks held in Princeton May 18-19, 2017, with Carlson, Briggs, Petzold, and Valentine in attendance from UCSB.

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CHALLENGE GRANT PROGRAM

• The goal of this workshop was to bring together a select group of Princeton faculty from a range of departments and research fields to interact through brief presentations and informal discussions to facilitate potential collaborations and catalyze new and transformative research in this area. • The Princeton group was joined by CANDy PI’s from UCSB (physics, biology, engineering, computer science) with the ultimate goal of identifying opportunities, challenges, and collaborations that provide the framework for a collaborative proposal uniting Princeton and UC Santa Barbara to establish a nationally-funded Center for Adaptive Network Dynamics (CANDy).

• The team aims to explore the role of dynamics and feedback operating over multiple length and time scales to control the behavior of complex, interconnected systems/networks, with an emphasis on biological, ecological, social and technological systems. Overarching themes include self-organization, emergence and resilience, physical adaptive structures, adaptive signaling, disease and the adaptive immune system, social networks and decision making.

(3) Bi-Weekly CANDy Lunch Meetings Spring Quarter (10-15 participants per event): As follow up to the December Workshop on Adaptive Network Dynamics at UCSB, the team held a series of bi-weekly lunches focusing on collaborations and teaming in topical areas involving Adaptive Network Dynamics. The lunches were scheduled for every other Friday, from 11:30-1:30 in 3001 Elings Hall, starting on April 7th and ending on June 2nd, excluding May 19, due to the Princeton Workshop.

Each meeting was organized around a topic, with informal presentations and brainstorming. A list of topics and organizers is given below. A slide presentation was assembled for each meeting. The goal of these lunches was to discuss themes, challenges, technical approaches, and case studies with the highest potential for impact within each of the complementary thrusts of the Center for Adaptive Network Dynamics. Participants were encouraged to attend all of the meetings, not just those in their specific discipline, in order to develop links between thrusts of the center. Schedule and organizers: • April 7 (11:30-1:30, 3001 Elings Hall) : Network Neuroscience (Petzold and Carlson) • April 21 (11:30-1:30, 3001 Elings Hall): Ecological Networks (Briggs and Carlson) • May 5 (11:30-1:30, 3001 Elings Hall): Materials and Biomaterials (Valentine) • May 18-19: CANDy Collaboration Workshop at Princeton • June 2 (11:30-1:30, 3001 Elings Hall): Technological Networks (Mostafi)

(4) Additional group meetings and collaborations between team members, including but not limited to: Carlson & Simpson, Carlson & Goard, Carlson & Petzold, Carlson & Marden, Petzold & Carlson & Jacobs, Valentine & Foster.

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CHALLENGE GRANT PROGRAM

Grant Applications: (1) MURI White Paper submitted • Lead PI: Carlson, Co-I’s: Petzold, Doyle, Sejnowski, Castro, Peterson • Title: Coevolutionary dynamics in multilayer architectures: A multiscale approach to prevention of and recovery from mental health disorders • MURI Topic 6: Coevolution of Neural, Cognitive, and Social Networks: Mind-Body-Community Connections • FOA-N00014-17-S-F006

(2) NSF-Simons MathBioSys funding opportunity explored as a center opportunity with Princeton. • RFP for for NSF-Simons Research Centers for Mathematics of Complex Biological Systems http://www.nsf.gov/pubs/2017/nsf17560/nsf17560.htm • Carlson and Petzold attended Webinar. The call is not well suited to our team. (3) NIH U01 Research Project—Cooperative Agreements: PAR-15-085: Predictive Multiscale • Models for Biomedical, Biological, Behavioral, Environmental, and Clinical Research. • LOI Submitted for September 2017 submission: Multiscale Network Neuroscience linking sex hormones, brain changes, and cognition across the lifespan.

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CHALLENGE GRANT PROGRAM

Project: Reconfigurable Photonic and Electronic Materials

Start Date: July 1, 2016 PI: Michael Gordon, Professor of Chemical Engineering, UCSB Co-PIs: Jon Schuller, Professor of Electrical and Computer Engineering, UCSB; Dan Morse, Professor of Molecular, Cellular, and Developmental Biology, UCSB

Goal: Develop new proposals and whitepapers targeted to MURI and other Center-level programs within the theme of reconfigurable photonic and electronic materials.

Synopsis: The need for reconfigurable photonic and electronic materials underpins many recently announced DOE and DOD research programs. A recent DOE roundtable on Neuromorphic Computing and upcoming AFOSR workshop on Reconfigurable Electronics further echo the potential for transformative technological breakthroughs enabled by basic science research into reconfigurable materials and devices. The breadth of potential applications (e.g., neuromorphic computing, programmable photonic devices, adaptive and self-regulating sensors, electromagnetic lenses, beam steering, antennas, directed energy transfer, and evolutionary bio-mimicking machines) reflects the promise of reconfigurable materials and the importance of assembling interdisciplinary research teams that can attack a single problem from diverse directions.

The PIs will leverage the Challenge Grant funds to meet with program managers at the DOE and DOD agencies to cultivate scientific relationships to ultimately identify and assist in defining future MURI funding initiatives. The PIs will also host a number of workshops at UCSB to pull in collaborators and down-select between funding targets. Lastly, the Challenge Grant funds will be used for teaching relief taken to run the workshops and prepare the grant proposals.

Key Technical Achievements: • Gordon talks: 'Moth eye-based, graded index surface treatments to control reflection' (Invited) TMS Annual Meeting, Mar. 2017; 'Engineering nanostructures for photonics, energy, and materials characterization', U. Wash. Chem. Eng. Seminar, Mar. 2017; 'Bio-inspired photonics' (Invited) MEET Colloquium, UT-El Paso, May 2017; IEEE Photonics Society Workshop, UCSB, May 2017. • Morse & postdoc presented papers on Reconfigurable Biophotonic Proteins at the Asia-Pacific Marine Biotechnology Symposium, Honolulu, May, 2017; the IEEE Photonics Society Workshop, UCSB, May, 2017; and the Gordon Conference on Proteins, in Holderness, New Hampshire, June, 2017. In each, Morse pitched the upcoming CNSI-sponsored workshop. • Gordon made contact with new collaborators Drs. Neil Murphy and John Jones at AFRL. • Gordon/Morse will visit AFRL Photonics Branch in Oct. 2017 to discuss collaboration with Murphy/Jones + Structured Optical Materials and Processes Team on 'Tunable mixed-valent and plasmonic materials for tunable optical absorption and reflection'. • Schuller presented on 'Widely tunable semiconductor Mie resonators for reconfigurable metasurfaces' at the US-Israel Metamaterials Workshop. • Schuller established new collaboration Prof. Koby Scheuer from Tel Aviv University, in preparation for joint AFOSR/MAFAT (Isreaeli funding agency) proposal call.

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CHALLENGE GRANT PROGRAM

• Schuller helped organize team and White Paper for 2017 MURI Topic #17 • Gordon/Morse working on dielectric / lattice plasmon architecture (Figure) for tunable reflection: nanofabrication + FDTD simulations.

Si

SiO 2 d

d glass Au / Al Si

Wavelength [nm] Example HCP dielectric post array (formed by colloidal lithography) on SiO2/Au/glass, with SEM image of pattern transfer and FDTD simulations of optical behavior / tunability in the near IR region.

Team Development: • New collaborators at UCSB: Steve DenBaars (Matl.), Shuji Nakamura (Matl.), Craig Montel (MCDB), Deborah Fygenson (Physics), Stephen Wilson (Matl.), Suzanne Stemmer (Matl.) • Dr. Neil Murphy, Project Scientist, Photonic Materials Branch, AFRL • Dr. John Jones, Sr. Materials Engineer, Photonic Materials Branch, AFRL • Prof. Ramana Chintalapalle, Mechanical Engineering, UTEP • David Gorsich, Transportation Research, Development & Engineering Center (TARDEC), U.S. Army • Prof. Koby Scheuer, Electrical Engineering, Tel Aviv University • Lenny Rome (CNSI-UCLA), Gary Ren (DOE Molecular Foundry), Zhao Qin (MIT) • Maria Diaz Garcia, Physics, U. of Alicante; Gordon and Morse currently collaborating on organic materials for distributed feedback laser applications and tunable sensors. • Gordon and Morse initiating discussions with Anand Sampath (ARL-SEDD, Dir. of GaN research) and Ken Jones (ARL-SEDD) about GaN platforms. • Joseph Tischler (Naval Research Labs), Yuri Kivshar (Australian National University), Stephanie Law (University of Delaware), Thomas Taubner (Aachen University)

Selected Publications: • C.D. Pynn, L. Chan, F. Lora Gonzalez, A. Berry, D. Hwang, H. Wu, T. Margalith, D. Morse, S.P. Denbaars, and M.J. Gordon, Enhanced light extraction from free-standing InGaN/GaN light emitters using bio-inspired backside surface structuring, Optics Express 25(14) 15778-15785 (2017). • R. Levenson, D. DeMartini and D.E. Morse (2017). Molecular mechanism of reflectin’s tunable biophotonic control: Opportunities and limitations for new optoelectronics. Applied Physics Lett. (in press). • L. Chan, E.A. DeCuir, R. Fu, D.E. Morse, and M.J. Gordon, Biomimetic nanostructures in ZnS and ZnSe provide broadband anti-reflectivity, J. Optics (submitted Jun 17). • L. Chan, D.E. Morse, and M.J. Gordon, Moth eye-inspired improved detectors & LEDs, (invited review), Bioinspiration and Biomimetics, submitting 30 Aug 17.

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CHALLENGE GRANT PROGRAM

• P.P. Iyer, M. Pendharkar, C.J. Palmstrom, and J.A. Schuller, Ultrawide Thermal Free-Carrier Tuning of Dielectric Antennas Coupled to Epsilon-Near-Zero Substrates, Nature Comm. (accepted). • T. Lewi, H. Evans, N.A Butakov, and J.A. Schuller, Ultrawide Thermo-Optic Tuning of PbTe Meta- atoms, Nano Lett. 17, 3940 (2017).

Grant Applications: • ARO; Firefly-inspired Brighter Light for Increased Energy Independence; Gordon, Morse, DenBaars, Nakamura; pending. • ARO, Radical, New Rattlesnake-Inspired Paradigm for IR Detection; Montel, Morse, Gordon; pending. • ARO; Bio-inspired Nano-Emitters for Printed, Low Power Displays; Gordon, Morse, DenBaars, Nakamura, Margalith; not funded. • AFOSR/MAFAT; Dynamically Reconfigurable Metasurfaces Using MEMS Actuators; pending. • AFOSR; Functional Optoelectronic Heterostructures (MURI), not invited to submit full proposal.

CNSI Annual Report - 2016-2017 Fiscal Year 45

CHALLENGE GRANT PROGRAM

Project: Center for Recovering Chemical Resources and Energy from Waste Streams

Start Date: February 1, 2017 PI: Susannah Scott, Professor of Chemistry and Chemical Engineering, UCSB Co-PIs: Mahdi Abu-Omar, Professor of Chemistry and Chemical Engineering, UCSB; Sangwon Suh, Professor, Bren School of Environmental Science and Management, UCSB

Goal: Develop the research thrusts and assemble the team for the creation of a Center focused on transforming polymers, agricultural and food waste to valuable chemicals, specialty fuels, and materials.

Synopsis: Sustainable manufacturing will require a shift from cradle-to-grave thinking towards cradle-to-cradle recycling. Already widely practiced for metals, this Challenge Grant aims to extend this concept to organic materials via chemical disassembly, separation, and upgrading. The target organic waste streams are those containing synthetic and naturally-occurring macromolecules, notably, polymers, lignocellulosic agricultural wastes, and food waste. Problems of waste will be tackled through development of sustainable catalytic and biological transformation technologies to recover valuable chemicals and fuels from agricultural and food waste as well as synthetic polymers. Examples of the intended uses for the recycled chemicals include specialty fuels (such as jet and diesel), lubricants, surfactants, and novel materials. A multi-disciplinary team that includes experts in molecular synthesis, catalysis science, separations, bio- and microbial transformations, chemical engineering, polymer science, and life cycle analysis (LCA) will be assembled in order to compete in the NSF Science and Technology Center (STC) funding call expected in 2018.

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CHALLENGE GRANT PROGRAM

Project: Bio-Building Blocks for Advanced Materials (BBAM)

Start Date: February 1, 2017 PI: Rachel Segalman, Professor of Chemical Engineering and Materials, UCSB Co-PIs: Glenn Fredrickson, Professor of Chemical Engineering and Materials, UCSB; Michael Doherty, Professor of Chemical Engineering, UCSB; Michelle O’Malley, Professor of Chemical Engineering, UCSB; Craig Hawker, Professor of Chemistry and Materials, UCSB

Goal: Leverage recent DOE investments in synthetic biology and materials science to develop a Center focused on unique high performance polymers derived from microbially-produced monomers.

Synopsis: Over the last 10 years, DOE Biological and Environmental Research (BER) Division has invested heavily in the development of synthetic biology tools while a broader community has questioned the limits of biosynthesis in terms of both molecular sophistication (for high value targets) and scale (for biofuels). Polymers are a unique target as the largest revenue segment of the commodity chemicals market at about 33 percent of the basic chemicals dollar value. More importantly, monomers represent a class of chemicals where the sophistication of biology in making unique asymmetric and chiral structures can be utilized to design materials with superior properties. Consumer-facing companies are seeking to offer products and packaging that can be seen and advertised as “sustainable” or “green,” while chemical and materials companies that supply polymer resins, coatings, adhesives, and packages to these companies - their customers - would like to provide a broad range of sustainable offerings. This Challenge Grant will exploit the powerful new tools of synthetic biology to create building blocks from sugar sources that are unique and inaccessible via conventional synthetic routes. These building blocks will then be used in homopolymerizations, copolymerizations or to modify existing materials leading to thermoplastic and thermoset polymer resins with improved and/or new performance. A team combining expertise in synthetic biology with polymer synthesis, characterization, theory, and critically, process design and economics will tackle this problem and apply for DOE and NSF funding.

CNSI Annual Report - 2016-2017 Fiscal Year 47

CHALLENGE GRANT PROGRAM

Project: Center for Formulated, Functional Goos

Start Date: July 1, 2017 PI: Todd Squires, Professor of Chemical Engineering and Materials, UCSB Co-PI: Patrick Spicer, Associate Professor of Chemical Engineering, University of New South Wales, Australia

Goal: Create an educational center focused on multifunctional formulated material that serves both industrial and academic participants and can lead to sponsored research on projects of direct interest to industry.

Synopsis: Multifunctional formulated materials, such as shampoos, drilling muds, paints, vaccines, and yogurts, are produced and exploited across a wide range of industries: from consumer products, foods, oil & gas production and development, pharmaceuticals, specialty chemicals, agriculture, biotechnology and biomaterials, household and construction materials. The technologists responsible for these multifunctional materials have science or engineering backgrounds. No discipline, however, actually teaches the conceptual design of formulated chemical products. Consequently, product design in industry often advances in a conservative fashion, with new products developed through small changes to existing recipes.

The long-term goal of this Challenge Grant is to bridge the academic/industrial divide in the formulated products and soft materials space; and to therefore establish UCSB as a central nexus of expertise, interaction, and inspiration in this realm. Envisioned is a center that supports a variety of activities, including: (i) technical short-courses for industry professionals and Ph.D. students and postdocs, in the area of soft materials and formulated product design; (ii) promoting technical exchanges and internships, between academia and industry; (iii) building industrial-academic relationships that may result in sponsored research.

CNSI Annual Report - 2016-2017 Fiscal Year 48

ELINGS FELLOWSHIP PROGRAM

ELINGS PRIZE FELLOWSHIP PROGRAM

A cornerstone of the California NanoSystems Institute (CNSI) is the international Elings Prize Postdoctoral Fellowships in Science, designed to bring the best and brightest scientists and engineers to UCSB. These fellowships have proven to be extremely successful with over 100 applicants per year in experimental nanoscience covering all areas of the physical sciences, biology and engineering. The fellowships are designed as a bridge between a traditional post- doctoral fellowship and an independent research position, providing an annual salary of $60,000 for a minimum of two years, along with benefits and $5,000 in research funds. The following Elings Fellows were supported during the 2016-2017 fiscal year:

REVITAL KAMINKER Revital was born in Israel and carried out her undergraduate studies in chemistry at Tel Aviv University (B.Sc., cum laude, 2006). She received her M.Sc. (2009) and Ph.D. (2014) from the Weizmann Institute of Science, where she worked with Professor Milko E. van der Boom on molecule-based assemblies on solid surfaces and in soft matter. She collaborated with the Nitschke group from the University of Cambridge on the formation of surface-confined helicates. Revital joined CNSI as an Elings Fellow in July 2014 and is working in the research group of Professor Craig Hawker.

JOHN LABRAM John was born in Bath, United Kingdom, and received his undergraduate degree in Physics from the University of Warwick in 2008. He received his Ph.D. from Imperial College London in Experimental Solid State Physics in 2011. During his Ph.D. John studied ambipolar organic field-effect transistors under the supervision of Professor Thomas Anthopoulos. Between 2011 and 2013 John took a break from academia and worked for the Royal Bank of Scotland as a currency-options trader. John joined CNSI as an Elings Fellow in November 2014 to work in the research group of Professor Michael Chabinyc.

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ELINGS FELLOWSHIP PROGRAM

LISA KOZYCZ Lisa was born and raised in Ontario, where she received her B.S. with Honours in Chemistry from Queens University in 2010. Her undergraduate thesis focused on tertiary amines for use as switchable hydrophilicity solvents that could be applied to the recycling of polystyrene foam. As a graduate student at the University of Toronto, Lisa extended her interest in earth-friendly research, co-founding the Green Chemistry Initiative – proposing and advancing eco-responsible practices inside and outside the lab, in an effort to reduce waste production and energy consumption. Lisa completed her Ph.D. in polymer and materials chemistry under the supervision of Prof. Dwight Seferos, designing new block and statistical thiophene copolymers with optimal energy levels to use in organic solar cells in 2015. Lisa joined the Chabinyc group upon her arrival in October 2015.

VICKY DOAN-NGUYEN Vicky was born in Vietnam, and she received her B.S. in 2006 from Yale, double-majoring in both Chemistry and Women’s Studies. Since then, she has remained an active advocate for women in science. At Penn, she served as the Chair of the Penn Graduate Women in Science and Engineering, and teaches material science as part of a summer program geared towards high school girls. In 2013, Vicky interned for the White House Office of Science and Technology, conducting research and analysis of STEM education policy, as well as the impact of high- performance computing on science industry. Vicky completed her Ph.D. in 2015 from the University of Pennsylvania, focusing on the synthesis, structural characterization, and functional testing of transition metal, metal phosphide, and metal oxide nanomaterials for applications in fuel conversion, electrocatalysis, and optical switching. Vicky joined CNSI in July 2015 to work with the Seshadri group at UCSB and Bruce Dunn at UCLA.

AMILA ARIYARATNE At the age of 4, Amila moved to Sri Lanka from Texas. In 2009, he received his B.Sc. in Physics from the University of Peradeniya. Amila completed his Ph.D. at UCLA under the supervision of Prof. Giovanni Zocchi in experimental molecular biophysics in 2015. As a grad student, Amila collaborated with the Mayans group at the University of Liverpool on mechanical control of the protein Twitchin kinase using DNA springs and with Prof. Elisha Moses at the Weizmann Institute on introducing artificially controllable ion channels to cultured neurons. Amila joined the Jayich group in August 2015.

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ELINGS FELLOWSHIP PROGRAM

ATHINA ANASTASAKI Born in Greece, Athina graduated from the University of Athens in 2011 with 1st Class Honours in Chemistry. Under the supervision of Marinos Pitsikalis, she developed her independent undergraduate research project into her first publication. In 2013, Athina received the EPSRC Transatlantic fellowship, which enabled her to conduct research at the University of Pennsylvania. She completed her Ph.D. entitled “Shining a Light on Copper Mediated Living Radical Polymerization: Maximizing End-Group Fidelity” in 2014 at the University of Warwick as part of the Haddleton polymer group. Before joining CNSI, Athina served as a joint research fellow with Monash University in Australia. Athina joined the Hawker research group in January 2016.

ERIC SPANTON Eric grew up in the Chicago area and then received his B.S. in engineering physics from the University of Illinois at Urbana-Champaign (2010). He then received his Ph.D. in physics from Stanford University (2016) for work completed in Kam Moler's group doing low- temperature magnetic imaging of complex oxide heterostructures, prospective 2D topological insulators, and induced superconductivity in semiconductor nanowires. Eric joined the research group of Andrea Young in July 2016.

DORIV KNOP Doriv was born and raised in Israel. She is married and has two daughters. Doriv carried out her undergraduate studies in Biochemistry and Food Science at the Hebrew University of Jerusalem (B.Sc.Agr. as magna cum laude, 2008) as well as her M.Sc. (Biotechnology, 2011) and Ph.D. (2016) under the direction of Prof. Yitzhak Hadar and Prof. Oded Yarden on the ligninolytic system of the white rot fungus, Pleurotus ostreatus. She joined Michelle O'Malley’s lab in the Department of Chemical Engineering and CNSI at UCSB in 2016. At UCSB, she is working on characterizing cellulosomes, which are powerful biomass-degrading machines made by anaerobic fungi. The main goal of her research is to illuminate the structure and function of these multi-enzyme complexes, and transfer lignocellulose-degrading abilities to industrially relevant microbes to produce sustainable chemicals.

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ELINGS FELLOWSHIP PROGRAM

ELINGS PRIZE FELLOWSHIP ALUMNI:

Elings Prize Fellow Year Current Position Employer Department of Chemistry John Franck 2009 Assistant Professor University of Syracuse Institute for Quantum Computing Matteo Mariantoni 2009 Assistant Professor University of Waterloo, Canada Corporate Innovation Division Jason Spruell 2009 Principal Scientist Eastman Chemical Company Nanoscale Science and Technology Division Abram Falk 2010 Research-Staff Member IBM Department of Chemistry and Chemical Biology Brett Fors 2011 Assistant Professor Department of Physics and Astronomy Adam Hauser 2012 Assistant Professor University of Department of Environmental Science and Engineering Himanshu Mishra 2013 Assistant Professor King Abdullah University of Science and Technology Department of Chemistry Zachary M. Hudson 2014 Assistant Professor University of British Columbia, Vancouver Department of Electrical and Computer Engineering John G. Labram 2014 Assistant Professor University of Oregon Institute of Technology Lisa Kozycz 2015 Grants Officer University of Ontario Department of Materials Science Engineering Vicky Doan-Nguyen 2015 Assistant Professor The Ohio State University

CNSI Annual Report - 2016-2017 Fiscal Year 52

FUNDING SUMMARY

FUNDING SUMMARY 2016-2017

Contracts and Grants

50 Proposals Submitted

~$25.4M Total Value of Contracts and Grants Administered

$ 18M Federal (DoD, NIH, NSF, etc.) $2.9M Other Non-Profit (Foundation) $4.3M Industry

~$5.8M Contracts and Grants Incremental Funding Received

44 Awards

28 Agencies

62 Principal Investigators

18 Departments

Gifts/Endowments

$556.9K Research Gifts

$370.4K Unrestricted Gifts and Endowments

CNSI Annual Report - 2016-2017 Fiscal Year 53

AWARDS ADMINISTERED

AWARD ADMINISTRATION

AIR FORCE Nanoscale Probe of Magnetism Based on Artificial Atoms in Diamond 09/01/2013-08/31/2018 Award #: FA9550-13-1-0198 $800,000

PI: Ania Jayich, Physics

The goal of the work proposed is the construction of a scanning magnetometer capable of detecting single spins with ~ 1 nanometer spatial resolution. This tool will have a significant impact on a broad range of fields, including basic physics, materials science, classical and quantum computation, and biology. The magnetic sensing element is a nitrogen-vacancy (NV) color center in diamond, an impurity that acts like a solid-state atom. The scanning NV magnetometer will be used as a local, nanoscale probe of magnetism in materials of technological relevance: multiferroics and single molecule magnets. We will also combine local electric field sensing with local magnetic field sensing in the same probe, opening a window into interplay of spin and charge in condensed matter systems. By addressing materials issues and identifying and inimizing decoherence mechanisms, the sensitivity of the magnetometer will be continually improved towards along-term goal of magnetic resonance imaging of single nuclei for structural determination of biological molecules.

Quantum Memories in Photon - Atomic - Solid-State Systems (QuMPASS) 11/01/2011-04/30/2017 Award #: FA9550-12-1-0004 $7,500,000

PI: David Awschalom, Physics Co-PI(s): Ania Jayich, Physics

Dramatic recent advances in realizing the critical enabling concepts of quantum information science (QIS) in atomic and solid state systems has provided the characteristics of long-term coherence and entanglement of qubit ensembles. Atoms within appropriate traps or cavities have the advantage of uniquely defined transition energies, insensitivity to environment, and long coherence times. Solid state systems have the advantage of higher oscillator strength, scalability and potential large-scale replication, but face greater challenges in decoherence. We propose a revolutionary hybrid quantum memory system that incorporates the long coherence times of atomic qubits and the high-speed quantum operations and scalability of solid-state qubits with the‘quantum wiring’ afforded by photonic qubits to achieve scalable circuits with fast gate operations and reliable quantum memory. The team will implement scalable uantum circuits by integrating micro-and nanoscopic optical networks with emitters (atomic or solid-state) to achieve quantum functionality.

QuMPASS will develop the systems architecture and engineer the light-matter interactions for a hybrid quantum memory incorporating both atoms and NV centers as the stationary qubits, linked by high quality solid state optical cavities that will transduce the quantum information from stationary qubits to CNSI Annual Report - 2016-2017 Fiscal Year 54

AWARDS ADMINISTERED

photons in a compact, on-chip footprint. These photons, through fibers and on-chip waveguides, will form a photonicus linking spatially-separated multipartite memories. A critical development goal of the QuMPASS plan is ‘atom buses’: nano-fiber optical traps that serve as a nanoscale interface between atomic and solid state memories, cavities and devices. We will integrate high quality diamond nanocrystals with high -Q photonic crystals and resonators using advanced positioning procedures, create strongly confining, versatile optical potentials for neutral atomic localization within nanometersof lithographically patterned optical structures, tailor color center spectra and micro-photonic wavelength conversion to realize the photonic interface, use high-bandwidth modulation for real-time reconfiguration of optical circuits (on-chip multiplexing and resonator switching), and fabricate microscopic optical elements for optical field transport, including input and output from high-Q resonators.

Scanning Magnetometry of Low Dimensional Electronic Systems 05/01/2016-04/30/2019 Award #: FA9550-16-1-0252 $289,506

PI: Andrea Young, Physics

Understanding electronic and thermal transport and magnetic and superconducting structure at the nanoscale is essential for the development of new functionalities derived from novel material platforms and device architectures. Rapidly advancing progress in materials synthesis and device fabrication challenge existing experimental measurement techniques, demanding ever greater versatility, throughput, and sensitivity. Techniques capable of measuring multiple physical quantities, in situ, on the nanoscale are of particular value. We propose the design and construction of a cryogenic scanning probe microscope for topographic, thermal, and magnetic imaging, based on a scanning nanoscale Superconducting QUantum Interference Device (SQUID) fabricated on the tip of a pulled quartz pipette. Our next generation nano-SQUID-on-tip (nSOT) microscope will bring unique capabilities to bear on topological states of matter, magnetic systems, and electronic devices by combining sub-single spin sensitivity, sub-m K thermal sensitivity, and <50 nm nanometer spatial resolution in a cryogenic (300mK-7K), high magnetic field (0-2T) environment. nSOT microscopy already far outstrips conventional scanning magnetometers along most metrics, and no other microscopy technique offers ultra-sensitive magnetometry and thermometry in a comparable regime of temperatures and magnetic fields. The proposed instrument is expected to enhance capabilities through the integration of topographic feedback, provide higher spatial resolution imaging and higher sensitivity to sample temperature, current, and magnetization. We will use the microscope to probe topological edge currents in 2D layered materials, perform precision thermal measurements of neutral mode transport in magnetic systems, and correlate magnetic structure and transport in low dimensional magnetic electron systems.

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Electrically Reconfigurable Infrared III-V Phased Array Metasurfaces 09/30/2016-09/29/2019 Award #: FA9550-16-1-0393 $130,000

PI: Jon Schuller, ECE

The possibility of engineering electromagnetic phase at subwavelength dimensions has led to “metasurfaces” that provide unprecedented control of electromagnetic waves. The ability to electrically tune this phase would unlock the potential of metasurfaces and establish disruptive new paradigms in reconfigurable optics. The objective of this proposal is to construct first-ever fully reconfigurable metasurfaces by exploiting voltage-controlled, free-carrier based tuning of mid-infrared resonances in III-V semiconductor resonators. The approach is to (1) grow InAs-based heterojunction devices capable of order unity and larger refractive index modulations across micron length scales; (2) demonstrate ultra-wide wavelength tuning of individual micron-scale “Mie resonators” using high spatial resolution infrared spectroscopy; and (3) design and demonstrate low-loss electrically reconfigurable phased-array metasurfaces with high diffraction efficiency. The central challenge of making 2π-reconfigurable metasurfaces is the need for very large refractive index modulation (Δn≥1) due to the subwavelength scale of the underlying resonators. This proposal aims to solve this technical challenge through free- carrier based tuning of Indium Arsenide and Indium Antimonide mid-infrared permittivities (ε) between 16-1. Electrically tunable resonators will exploit unique forward-biased heterojunction devices to swing carrier concentrations between 1017 and 1018 cm-3 across large widths in ways that cannot be achieved with typical device architectures. These investigations will thus explore extreme frontiers of the physics and engineering of free-carrier refraction effects and advance understanding of fundamental optical antenna and metasurface concepts. The advent of reconfigurable metasurfaces based on the approaches described here would enable new classes of programmable optics and unprecedented control of electromagnetic beam-forming.

AMERICAN DIABETES ASSOCIATION

Untethering diabetes through innovative engineering 01/01/2017-12/31/2017 Award #: 1-17-VSN-18 $325,000

PI: Sumita Pennathur, Mechanical Engineering

Achievement of good glucose control in patients with diabetes depends on frequent self-monitoring of blood glucose values and appropriate insulin adjustment and administration. Avoiding such control can result in hypo- and hyperglycemia and life-threatening diabetic ketoacidosis. Therefore, it is not surprising that there exists a plethora of research focused on the effective daily and continuous glucose monitoring; over 100 different technologies have attempted to go to market. Despite this enormous effort, only two continuous glucose monitors (CGMs) have achieved FDA approval and commercial realization in the last 27 years (Dexcom and Medtronic, Inc.). Still worse, because of the painful, invasive, cumbersome (e.g., require calibration) nature of these devices, they are utilized by only 10% of the Type 1 patients. All approaches to CGM have also repeatedly failed in terms of the sensitivity

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required for real-time insulin dosing. Therefore, the PI proposes to leverage her combined strengths of MEMS, microfluidics and bio-sensing to fabricate painless, continually actuated microneedles for CGM. This solution will allow for a facile, painless, disposable patch that can be adopted by not only the Type I community, but also Type 2 diabetes as well as pre-diabetics, truly achieving the goal of good glucose control for all. Given her past accomplishments in both microfluidics and microfabrication, this ADA Visionary award affords the springboard she needs launch into a new path.

ANGSTROM DESIGNS (NASA STTR PHASE II) NASA STTR Phase II Proposal: LED-based Lab Solar Simulator 12/17/2014-12/31/2017 Award #: NASA STTR UCSB 091714-UCSB02 $225,000

PI: Sumita Pennathur, Mechanical Engineering

During Phase II, Professor Pennathur and her research team will further assist with extensive LED and system testing, scientific input/oversight, and identification of commercialization opportunities within the research and academic communities. UCSB will perform testing and provide guidance and support for application science, research, design and analysis.

Modular, Embedded Sensor Network 06/10/2016-12/09/2017 Award #: NASA STTR UCSB – 061016 – UCSB 003 $38,000

PI: Sumita Pennathur, Mechanical Engineering

In this work, I will be providing technical guidance at all levels, particularly in the areas of energy harvesting and nano-sensors. In addition, our group will initiate and collaborate to research and fabricate advanced sensors of interest to NASA. Specifically, we will use our expertise in MEMS and actuation to develop individually actuated sensors that will sense a variety of environmental aspects that are relevant to NASA, such as temperature, chemical signatures, and aerosols.

ARMY RESEARCH OFFICE Alkaline Earth Quantum Gas Microscope for High- Resolution Imaging of Ultracold Strontium 08/15/2015-11/14/2016 Award #: W911NF-15-1-0436 $199,439

PI: David Weld, Physics

Two of the most exciting recent developments in atomic physics have been the advent of quantum gas microscopy and the production of degenerate alkaline earth gases. Single-lattice-site-resolved quantum

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gas microscopy has allowed unprecedented insight into the behavior of controllable quantum systems, but to date has been demonstrated in very few experiments, all using rubidium. In parallel with these advances, ultracold atomic physics has expanded beyond the first column of the periodic table to alkaline earth species such as strontium and ytterbium, opening up new horizons for the investigation of exotic quantum phases, simulation of complex materials, and quantum sensing. This proposal is for an instrument which will combine both these break-throughs: a quantum gas microscope for high- resolution studies of ultracold alkaline earth atoms. The instrument will be added to the ultracold strontium apparatus which is the subject of our existing AFOSR YIP grant FA9550-12-1-0305, and will significantly enhance its research capabilities, while opening up new possibilities for our investigations of nonequilibrium quantum dynamics (funded by ARO PECASE award W911NF-14-1-0154) and tunable quasiperiodic quantum systems (funded by ONR award N000141410805). The precision and control inherent in single-site resolution will enable rapid progress towards and beyond the goals of all three projects, including production and characterization of novel quantum fluids, detection and manipulation of edge states in cold atom quasicrystals, and high-spacetime-resolution studies of dynamical quantum phenomena. Furthermore, the instrument will enable new experiments not currently possible with any apparatus. Because the assembly, installation, and operation of this novel instrument will be performed largely by graduate students and postdocs, the alkaline earth quantum gas microscope will also give rise to unique research-related educational opportunities for scientists in training at UCSB.

Nonequilibrium Dynamics with Ultracold Atoms 05/12/2014-05/11/2018 Award #: W911NF-14-1-0154 $700,000

PI: David Weld, Physics

Predicting and controlling the behavior of non-equilibrium many-body quantum systems is a major challenge of modern physics. In addition to having fundamental importance for quantum statistical physics, advances in the understanding of non-equilibrium quantum dynamics have potential applications to phenomena in a broad range of fields, from materials science to quantuminformation. Existing theoretical and experimental tools for addressing many-body systems far from equilibrium are limited. Due to their experimentally accessible timescales and exquisite controllability in both space and time, optically trapped ultra cold atomic gases are an ideal context in which to study many-body non- equilibrium dynamics in the quantum regime. We propose to develop and demonstrate an experimental platform enabling a broad range of fundamental experiments in non-equilibrium many-body quantum dynamics. We will use ultra- cold lithium atoms in dynamically configurable optical traps to investigate two broad classes of non- equilibrium phenomena: quantum quenches and driven systems. Proposed experiments include a demonstration of dynamic stabilization and quantum chaos in a modulated optical lattice, measurement of quench dynamics in one- and two-component systems, experimental tests of the eigenstate thermalization hypothesis, and development of driving techniques for the preparation of topologically nontrivial states.

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Towards Synthetic Nonabelions in Graphene Heterostructures 08/17/2016-08/16/2018 Award #: W911NF-16-1-0482 $200,000

PI: Andrea Young, Physics

The goal of this proposal is to use graphene heterostructures as a platform for engineering nonabelian defect states, including Majorana and parafermion bound states.

Graphene heterostructures are an ideal system to pursue synthetic nonabelions, providing viable routes to realizing all of the requirements for engineering, detecting, and manipulating Majorana and parafermion bound states (MBSs and PBSs) at current levels of technology. Two major experimental challenges prevent the immediate realization of MBS and PBSs in graphene heterostructures: lack of a complete phase diagram of integer- and fractional-quantum Hall states in bilayer (BL) and double layer (DL) systems most promising for engineering nonabelian defects, and insufficient understanding of the physics of QH interfaces, the tailoring of which forms the basis for all synthetic parafermion proposals. Our approach is to: • Classify the electronic phases of graphene double layers using a novel thermodynamic technique (year 1-2) • Control superconducting proximity effects (year 1), interlayer tunneling (year 1-2), and symmetry breaking in helical edge state (year 1), using MBS detection as a benchmark (year 2) • Combine these results to enable parafermion detection in graphene bilayers and double layers (year 3).

HBCU/MI Acquisition of UV/Vis/Raman Spectroscopy and Imaging Instrumentation for Physics and Engineering Research 08/01/2016-07/31/2018 Award #: W911NF-16-1-0427 $499,652

PI: Andrea Young, Physics Co-PI: Michael Gordon, Chemical Engineering

Acquisition of UV/Vis/Raman spectroscopy and imaging instrumentation for chemical and structural characterization of materials. The proposed facility will contribute to the research and development of next-generation materials for electronic devices, medical diagnostics, energy storage and harvesting, and surface protection that are relevant to the Army and DoD. Within the UCSB campus alone, impacted DoD-funded research ranges from basic (TLR 1) investigations of the optoelectronic properties new two-dimensional heterostructures to antireflective coatings undergoing testing in collaboration with ARL (TRL 5/6). Moreover, the facility will provide an important educational tool and training venue for undergraduate, graduate, and post- doctoral students through its incorporation into coursework on light-matter interactions and materials characterization. The facility will become part of the Materials Research Facilities Network (MRFN), a collaborative effort focused on increasing the visibility and usage of analytical and computational CNSI Annual Report - 2016-2017 Fiscal Year 59

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instrument centers. The MRFN particularly emphasizes access by MSI partners, with the purpose of attracting more students to graduate research and improving retention through access to state-of- the-art facilities. MRFN users typically submit short proposals requesting access to instrumentation, techniques, and highly skilled staff. Undergraduates will be recruited through existing programs administered by the MRL. These programs target undergraduate stud ents from underrepresented groups in STEM fields from various institutions (research/teaching universities, community colleges, and junior colleges) throughout California and the US.

ARMY RESEARCH LABORATORY

3a: Microbial Consortia and Biofilms Workshop 01/27/2017-09/26/2017 Award #: W911NF-17-1-0085 $30,000

PI: Michelle O’Malley, Chemical Engineering

This proposal requests funding for a workshop on Microbial Consortia & Biofilms to be held on the UC- Santa Barbara campus March 16-17, 2017. Funding for the workshop will enable approximately 15-25 academic participants to join in discussion with government researchers about the current state-of-the- art of this field, gaps in knowledge, and opportunities for technology development as applied to areas of research interest for the US Army. Together, participants will brainstorm the development of new tools that interrogate natural systems to direct the assembly of synthetic consortia and biofilms for bioproduction. This meeting will integrate expertise from those currently working in the field with perspective from PIs from different fields (e.g. tissue engineering, materials science) to broaden the range of tools considered. The outcomes of this workshop will be captured in a publication highlighting discussion topics and technology solutions, that will be publicly available to the scientific community.

ARNOLD AND MABEL BECKMAN FOUNDATION

Developing Biomimetic Antibiotics via Siderophore Inspired Self-Assembling Polymers (SInAPs) 09/01/2016-08/31/2017 Award #: SB160162 $61,755

PI: Abigail Knight, CNSI

This award is a Postdoctoral Fellowship.

Aim 1: Bioinspired metal-induced self-assembly of polymeric nanomaterials. The development of a bioinspired materials platform, which changes morphology in the presence of metal ions.

Aim 2: Rational design and evaluation of antibiotic SInAPs. The design and evaluation of a SInAPs system that mimics the

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BIOSOLAR

Bio-Inspired Redox-Active-Polyelectrolytes (RPE) 07/01/2014-10/17/2016 Award #: SB140157 $375,402

PI: Alan Heeger, Chemistry & Physics

We propose a research program for polymer-based supercapacitors and batteries employing interpenetrating polymer-networks to give stable polymer-electrodes with very high charge-storage capacity. The network consists of an electron-conducting polymer and a highly–capacitive redox- polymer. Inspired by nature we propose a novel kind of bio-Redox-Polyelectrolytes (RPE) which structure is similar to that of polystyrene PSS. We expect high cycling-stability and lowered self- discharge rates when using the novel RPE.

DOD ADVANCED RESEARCH PROJECTS AGENCY (DARPA) Encode-Sort-Decode (ESD): Integrated System for Discovery of Non-Natural Affinity Reagents 09/01/2014-08/31/2017 Award #: N66001-14-2-4055 $2,751,673

PI: Craig Hawker, Chemistry & Materials

There has been significant investment in the past two decades for generating synthetic affinity reagents that surpass monoclonal antibodies in affinity and specificity for binding to their target molecules. In particular, the use of non-natural polymers offer the exciting possibility that these reagents could be more stable, economical and offer functionalities that cannot be achieved with natural polymers. Unfortunately, the progress in using non-DNA coded polymers, such as non-natural amino acids and peptoids through combinatorial chemistry has faced significant challenges. This is readily apparent from the fact that typical reagents generated from such combinatorial approaches have yielded molecules with Kd’s in the low micro-molar range, which are far inferior to monoclonal antibodies. The overall goal of our project is to develop an advanced integrated system to rapidly generate heterobivalent peptoid reagents (HPR’s) that can bind to target molecules with superior affinity and specificity than monoclonal antibodies, offer unprecedented stability and can be economically scaled up to gram quantities. To achieve these challenging goals, our system (called ESD-Encode-Sort-Decode) combines innovations and expertise from multiple disciplines.

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GOOGLE, INC.

Quantum Information Processing with Xmon Qubits 08/28/2014-08/27/2017 Award #: PO251948 $3,724,952

PI: John Martinis, Physics

This research project aims to characterize and test fabrication technology for wiring crossovers using airbridges, to be used on A1 qubits on Silicon wafers. It will entail performing various experiments in the UCSB cleanroom, testing elements with high reliability and low amounts of defects. The research also includes testing resonator devices for energy loss from the crossovers, building a model if required to correlate the loss to imperfections in the airbridge. Finally, the research is expected to incorporate these airbridges in superconducting qubit devices, testing them for energy loss and dephasing decoherence effects.

JUVENILE DIABETES RESEARCH FOUNDATION Fundamental assessment of a MEMS-based pump for intraperitoneal delivery of concentrated insulin 08/01/2016-07/31/2018 Award #: 1-SRA-2016-294-S-B $499,998

PI: Sumita Pennathur, Mechanical Engineering

This objective of this work is to provide a scientific foundation for using a new formulation of highly concentrated insulin (needed for a long term implantable pump) in a silicon-based MEMS (microelectromechanical) pumping mechanism with unprecedented dose resolution and size as an enabling technology for a small, fully implanted intraperitoneal (IP) artificial pancreas. To provide the scientific foundation, we have three equally important but distinct aims, 1) to establish baseline properties needed for the concentrated insulin (U1000, provided by Thermalin) to ensure long-term stability for IP insulin delivery, 2) to establish baseline properties needed for a MEMS pump, and 3) to assess the performance of the pump with this highly concentrated insulin. Specifically, to establish baseline properties for concentrated insulin inside the MEMS pump, we will first look at the stability of insulin over long times, to determine whether it will form aggregates. Aggregates are known to change the behavior of fluid flow in small conduits, so we hypothesize that aggregates of insulin forming will have detrimental consequences to the fluid flow inside a MEMS pump, and thus, pump performance. Therefore, we will perform studies using workhorse as well as new novel microfluidic methods to fundamentally study the formation of insulin aggregates over time. This will be through a combination of fluorescence techniques (for example, tagging the insulin with a fluorescent marker and watching the aggregates grow identified by a change in fluorescence intensity), or novel microscopy techniques (for example, focusing on the insulin, and performing time-lapse measurements with a new type of microscope built in the Pennathur laboratory that can measure when nanometer size objects form near a surface). Novel methods in the Pennathur lab will certainly help achieve this objective of understanding the concentrated insulin performance over time, and may also shed light into why and

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how insulin aggregates form. Next, we aim to perform tests with the MEMS pump, geometries of which will be provided to us by a large MEMS manufacturer. Here, we will test the pump for leaks using a variety of different geometries and pressures. Through these studies, we aim to find the limits of the pump in terms of operating pressures and flow rates, as well as determine whether such a system will be robust enough to withstand the human body. Finally, we will perform studies with concentrated insulin within the MEMS pump to make sure that there is no corrosion or long-term damage on the MEMS pump due to the insulin.

NATIONAL INSTITUTES OF HEALTH, CHILD HEALTH & HUMAN DEVELOPMENT

Biomechanics of gastrulation in zebrafish 07/01/2015-06/30/2017 Award #: 5R21HD084285-02 $410,698

PI: Otger Campas-Rigau, Mechanical Engineering

This exploratory research promises to reveal how Toddler signaling affects the differential forces generated by mesendodermal cells during ingression and migration, linking for the first time a molecular pathway controlling morphogenetic movements to the biomechanical properties that ultimately drive cell migration. We believe this study will provide a framework to understand how signaling events guide cell migrations via the spatiotemporal control of tissue and cell biomechanics.

NATIONAL INSTITUTES OF HEALTH, GENERAL MEDICAL SCIENCES UC Santa Barbara MARC Program: Bridges to Biomedical Research Careers 06/01/2015-05/31/2018 Award #: 5T34GM113848 $699,024

PI: Joel Rothman, MCDB

We propose a two-phased “Bridges to Biomedical Research Careers (BBRC)” program to enhance retention, and matriculation into PhD and MD/PhD programs, of underrepresented (UR) and disadvantaged students interested in pursuing careers in biomedical research. Nationwide, and at UC Santa Barbara, the greatest loss of UR students from STEM fields occurs during the first two years. Consequently, the first phase of the BBRC program will begin with a two-week summer bridge program and continued academic year support for 28 incoming freshmen each year of this five-year program that includes: tutoring in calculus, chemistry and physics; a mentoring network of peers, graduate students and faculty; and an introduction to research course called the “Practice of Science.” This will synergize with an HHMI-supported program emphasizing active learning courses and peer-to-peer learning communities. As they build community, and become aware of how their major fits into various research and career opportunities, students will be prepared to further develop as researchers through the next

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phase of the BBRC: the two-year MARC scholars program. Five top students will be selected as MARC scholars for each year of this program. In addition to acquiring extensive research experience, they will grow their leadership skills through various professional opportunities such as presenting at conferences, serving as mentors for lower division students, and developing a team-based community service project in the service -learning course “Science for the Common Good”. Although only five students from each cohort will receive MARC Scholarships, the other students in each group will be well- prepared to apply for other synergistic research internship programs available at our campus including UCLEADS and CAMP. Through the MARC U*STAR program our long-term goals are to: a) Enhance an institutional culture where students are immersed into a cohesive social, academic and research community which nurtures their success; b) Cultivate students’ confidence and skills that enable them to matriculate into and succeed in PhD or MD/PhD programs; c) Enable students to see how their studies are related to their broader interests and career goals, thereby providing motivation for their continued efforts; and d) Seed a lasting shift in the institutional culture to create a more inclusive environment for our entire campus community. UCSB is on track to become the first in the Association of American Universities (AAU) to reach Hispanic Serving Institution (HSI) status, putting UCSB on a short list of prominent research-intensive institutions serving a large number of Hispanic undergraduates. As such, we will have many eligible applicants to PhD and MD/PhD programs and success of this program will serve as a model for other similar R-1 institutions.

NATIONAL SCIENCE FOUNDATION

CAREER: An Integrated Approach to Neuron Mechanics: Deciphering the Functional, Mechanical, and Structural Interactions Between Microtubules and Actin 04/01/2013-03/31/2018 Award #: 1254893 $410,000

PI: Megan Valentine, Mechanical Engineering

Although prior experiments have probed isolated aspects of neuron biomechanics there have been few –if any– systematic efforts to understand the interconnectivity of the cell motility and axonal transport machinery, severely limiting our understanding of neurons as functional cellular systems. Using a suite of custom imaging and microscale manipulation tools, we will determine how the interactions between the microtubule and actin cytoskeletons control the functional and mechanical properties of neurons.

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CAREER: Enabling Efficient Non-Linearities in Biomechanical Simulations 02/01/2013-01/31/2018 Award #: 1253948 $508,658

PI: Theodore Kim, Media Arts and Technology

Great strides have been made in efficiently simulating biomechanical phenomena such as the flexing of a human bicep or fluid flow through an artery. However, the speed of existing methods still preclude their use in many transformative applications. At the macro scale, high-quality, interactive humans have yet to be achieved, but would revolutionize virtual surgery, and fundamentally change the use of digital actors in film and media. At the micro scale, the efficient simulation of flexible red blood cell-like structures in plasma flow would facilitate the design of cancer-treating micro-particles. If such systems are to be efficiently captured, the non-linearities that emerge as the problem complexities increase must be addressed. The scientific question we ask is: how can we efficiently compute the non-linearities that arise in complex biomechanical systems? A classic approach is spatially hierarchical methods, which usually yield speedups of roughly an order of magnitude. However, more drastic speedups are needed to enable the applications described above. We propose to investigate projected physics methods, which can yield speedups of three to six orders of magnitude, and are well-suited to biomechanical problems at multiple scales. These methods usually have trouble incorporating non-linearities, but our preliminary results suggest that efficient new algorithms can be devised. Our research will be driven by the two previously mentioned applications.

CAREER: Mechanical Control of single spins for sensing and quantum information processing 09/01/2014-08/31/2019 Award #: 1352660 $360,000

PI: Ania Jayich, Physics

This CAREER project will probe the fundamental interactions between a miniscule quantum object, a single electron spin, and the macroscopic motion of billions of atoms moving in unison, a phonon. The single spin is a nitrogen vacancy (NV) center in diamond: a model quantum system with atom-like properties that are uniquely accessible and controllable. The coupling between these two elements is mediated by deformations of the diamond lattice, i.e., strain, and is poorly understood. With its exquisite sensitivity, the NV center can be used as nanoscale quantum probe of spin-mechanical coupling; furthermore, harnessing this coupling could enable advances in NV-based quantum metrology and quantum information processing. NV centers are excellent magnetic sensors. Enhancements in their sensitivity through coupling to phonons could ultimately lead to nanoscale magnetic resonance imaging. In a hybrid quantum system comprising spins and phonons, phononic channels can mediate spin-spin interactions over long distances and provide a means for generating entanglement between NV spin qubits, a prerequisite for quantum information processing. Finally this juxtaposition of two systems existing at vastly different size scales enables fundamental explorations of macroscopic quantum mechanics and decoherence at the interface of quantum and classical worlds.

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CAREER: Origins and Applications of Optical Anisotropies in Organic Photonics 05/01/2015-04/30/2020 Award #: 1454260 $332,063

PI: Jon Schuller, ECE

Organic materials used in photonic devices often self-assemble into highly oriented morphologies, leading to huge optical anisotropies. The objective of this proposal is to elucidate the origins and applications of these anisotropies. The approach is to (1) develop new optical methods for characterizing anisotropies based on resolving the photon momentum vector; (2) identify distinct temporal and spectral signatures of intra- and inter-molecular luminescence; (3) quantify absorption anisotropies that challenge currently prevailing models of organic optical constants; and (4) integrate oriented organics with photovoltaic light-trapping architectures that exploit anisotropies to enhance thin-film absorption.

CAREER: Correlated Topological States in van der Waals Bilayers 06/01/2017-05/31/2022 Award #: 1654186 $159,368

PI: Andrea Young, Physics

The proposed work will implement novel fabrication and electrical measurement techniques to create a comprehensive phase diagram of twisted van der Waals (vdW) bilayers. The focus is on the search for new correlated topological phases hosting edge states. The results will test theoretical concepts at the intersection of symmetry, topology and electronic interactions, and form the basis for future engineering of electronic devices based on mesoscopic control of boundary modes. The PI’s group has developed a unique measurement technique capable of determining layer-resolved thermodynamic quantities in bilayers without the need for layer specific contact, allowing layer polarization to be unambiguously and quantitatively determined. This technique will be applied to twist-angle controlled vdW bilayers consisting of grapheme and transition metal dichalcogenides to realize new electronic systems based on spin, valley, and layer symmetries. These versatile systems present an excellent opportunity to exploit edge state electornic structure in an experimental setting where multiple observable quantities can measured, allowing tests of theoretical understanding of the interplay between internal degrees of freedom and topological order in the fractional quantum Hall effect and mesoscopic engineering of symmetry protected edge states in electronic devices.

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EAGER: Layer Resolved Capacitance in Graphene Bilayers 07/01/2016-06/30/2017 Award #: 1636607 $105,430

PI: Andrea Young, Physics

This EAGER proposal aims to leverage our recently developed technique for direct capacitive detection of charge order in van der Waals bilayers to classify the phase diagram of correlated topological states in these versatile heterostructures. This technique, proposed by the PI several years ago, has just been implemented at UCSB and is yielding impressive results that promise to solve long-outstanding questions in correlated electron physics of bilayer grapheme as well as other bilayer systems. It is appropriate for EAGER due to the timeliness of the results already being produced, which promise to shed light on a competitive area. The capacitive detection technique will be combined with novel twist angle controlled fabrication to create a comprehensive phase diagram of graphene bilayers, focusing on the interplay between bulk order and edge states. The results will test theoretical concepts at the intersection of symmetry, topology and electronic interactions, and form the basis for future engineering of electronic devices based on mesoscopic control of boundary modes. These versatile systems present an excellent opportunity to exploit edge state electronic structure in an experimental setting where multiple observable quantities can measured, allowing tests of theoretical understanding of the interplay between internal degrees of freedom and topological order in the fractional quantum Hall effect and mesoscopic engineering of symmetry protected edge states in electronic devices.

Cracking the Color Code of DNA-stabilized Metal

Nanoclusters with Rapid Optical Array Characterization and Machine Learning 09/15/2013-03/31/2018 Award #: DMR-1309410 $315,000

PI: Elisabeth Gwinn, Physics

The aim of this project is to combine computational machine learning tools with trategic data from fast, array format optical characterization to discover and develop a versatile new class of photonic nanomaterial: fluorescent, DNA-stabilized, few-atom metal nanoclusters, or “DNA-mNC”. DNA-mNCs based on silver clusters are already beginning to be used in innovative imaging, molecular logic, and selective sensor applications. The recent discovery of copper-based DNA-mNCs suggests that the formation of fluorescent clusters in DNA hosts may generalize to other coinage metals.

This project aims to “crack the code” for the sequence characteristics that govern the properties of DNA- mNCs, by applying machine learning to much larger, strategically selected data sets. The data will be acquired by robotic synthesis and rapid array optical characterization of Ag, Cu and Pt-based DNA-mNCs. Strand selection will leverage the knowledge of DNA-AgNCs developed in the PI's prior work.

The specific project goals are to: 1) Significantly increase the ability to predict DNA sequences and synthesis parameters that result in chemically stable, fluorescent DNA-mNCs with a desired color. 2) Gain understanding of the sequence motifs that code for DNA-mNC properties.

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I-Corps: Colorimetric sensors for the detection of volitile amine 11/01/2016-01/31/2018 Award #: 1661642 $50,000

PI: Read de Alaniz, Chemistry

The goal of this project is to evaluate the commercial feasibility of a colorimetric indicator for meat and seafood freshness. Specifically, the proposed project will perform customer discovery research within the food production, packaging, and retail markets, resulting in a definition of the market focus, the specifications for a minimally viable product, and a commercialization plan.

Complexity of Simulating Quantum Adiabatic Optimization by Quantum Monte Carlo Methods 09/01/2013-08/31/2016 Award #: 1314969 $250,000

PI: Willem van Dam, Computer Science

The PI proposes to investigate the question how well Quantum Monte Carlo (QMC) algorithms succeed in efficiently simulating the evolution of Quantum Adiabatic Optimization (QAO) algo-rithms in the setting where the Hamiltonians of the latter do not cause the minus-sign problem for the Quantum Monte Carlo algorithm. As Quantum Monte Carlo algorithms are, in fact, classical algorithms, this question therefore tries to determine to which extend Quantum Adiabatic Opti-mization (which is a proper quantum algorithm) will be able to outperform classical computation. The assumed absence of the sign problem refers to an important subclass of all possible quantum adiabatic Algorithms.

Strengths and Weaknesses of Simulated Quantum Annealing 09/01/2016-08/31/2019 Award #: 1620843 $200,000

PI: Willem van Dam, Computer Science

We propose to investigate in a rigorous manner the computational power of algorithms that simulate the quantum mechanical process of annealing. We will pay special attention to the ability or inability of quantum Monte Carlo algorithms in finding the ground state in settings where quantum adiabatically these states are found efficiently. It is sometimes claimed that quantum adiabatic optimization will be superior to classical optimization as it is able to quantum tunnel through barriers to find the global minimum of cost functions. There is however also recent evidence that path integral Monte Carlo algorithms are able to efficiently simulate this behavior. As part of this project we will analyze if the power of QMC tunneling is indeed identical to that of QAO tunneling. A situation where QMC seems to fail in simulating quantum adiabatic systems is in the presence of so-called ’topological obstructions’. We aim to investigate to which extend one can adjust QMC algorithms to overcome such obstructions. A third topic of research concerns the possibility of designing a black-box problem that can be solved efficiently using stoquastic adiabatic computation but that provably does not have an efficient classical simulation.

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Design of Tough Resilient Gels using Adhesive Rigid-rod Polymers 07/15/2014-06/30/2018 Award #: 1410985 $380,000

PI: Megan Valentine, Mechanical Engineering

This project will establish the fundamental structure-property relationships in adhesive rigid rod polymer networks using a model system of microtubules, extremely stiff protein-based polymers bonded by protein-based crosslinkers. Crosslinker kinetics and adhesion strength will be modulated through recombinant protein engineering to determine through experimentation how specific molecular features impact materials properties. In particular, this work will determine how stress propagates in adhesive networks, how crosslinker compliance and unbinding influence network response, and how dynamic changes in filament length influence stress relaxation.

Role of Motor/Cargo Attachment Mechanics in Collective Kinesin Transport 12/01/2013-11/30/2016 Award #: 1329722 $256,000

PI: Megan Valentine, Mechanical Engineering Co-PI(s): Otger Campas-Rigau, Mechanical Engineering

The goal of this proposal is to establish how the mobility of molecular motors at the surface of the cargos they transport affects their ability to cooperate and successfully move cargos. This study will address a serious limitation of the current in vitro approaches in which single kinesin motors are immobilized on plastic beads in a manner that is very different from that of vesicular cargos in cells, in which motors are attached to lipids or protein complexes that are mobile within the fluid lipid membrane. The mechanical properties of the cargo and the motor mobility at its surface are very important, as they have been shown to affect critically the ability of motors to cooperate and generate the necessary forces to move the cargo. Thus, although we now have an exceptionally good understanding of how individual motor proteins move in vitro, in many cases it has not been possible to leverage these results to understand biologically-relevant transport. In the proposed research, we will bridge this gap by developing a novel biomimetic cargo system consisting of phospholipid-stabilized oil droplets coated with kinesin motors via mobile linkages that freely diffuse at the interface. Unlike lipid vesicles, the droplets can be optically trapped and/or imaged with fluorescence microscopy, enabling a wide range of biophysical measurements, as shown in our preliminary studies. Additionally, we have exquisite control over cargo size, motor protein surface density and phospholipid interfacial rheology, as well as the mechanical and catalytic properties of the recombinantly-expressed motor proteins themselves. This provides an unprecedented opportunity to systematically test the effects of these parameters on cargo transport and kinesin dynamics, and will markedly improve our understanding of the role of interfacial mechanics in controlling cargo motions in cells.

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CHS: Small: ETouch - Amplifying the Sense of Touch 09/01/2015-08/31/2018 Award #: 1623459 $499,650

PI: Yon Visell, ECE; Media Arts & Technology

The overarching goal of this project is to create knowledge and technology for tactile sensing and feedback, in order to realize an electronic glove that will enhance touch perception by electronically amplifying tactile sensations, greatly extending the limits of normal human haptic (touch) perception. This will enable its wearer to feel touched objects with heightened sensitivity, and to discern fine levels of detail in surfaces, objects, or tissues. This will be accomplished through the design and fabrication of new soft computing technologies for capturing, processing, and reproducing touch sensations felt with the hand, in the form of strain and vibration signatures of skin-object contact.

This project will be executed through work in three main research areas (RA): RA1: Tactile sensing and computational analysis: Design and fabrication of novel devices and methods for contact-induced strain and vibration sensing of hand-object contact during palpation and grasping. RA2: Distributed actuation and control: Design, fabrication, and control of distributed soft tactile actuators capable of reproducing contact-induced signatures of skin-object contact; Calibration and real- time control. RA3: Real-time touch amplicication: Wearable instrumentation for real-time enhancement of touch during free hand movement and grasping. Evaluation of enhanced perceptual performance.

CPS: Breakthrough: From Whole-Hand Tactile Imaging to Interactive Simulation 09/01/2015-12/31/2017 Award #: 1628831 $408,330

PI: Yon Visell, ECE; Media Arts & Technology

The main objective of this project is to realize wearable technologies that make it possible to touch, feel, and manipulate computationally simulated objects using the whole hand. The project will create new methods for imaging complex tactile stimuli, consisting of movement-dependent skin strain and contact induced surface waves propagating in skin, and will model the dependence of these signals of hand movements and grasping. The resulting advances will be employed in wearable, whole hand interfaces that will employ surface wave and skin strain feedback to supply haptic feedback to the hand during interaction with real or computational objects, for application to virtual and augmented reality. The project is organized around three main research areas (RA):

RA1: Measurement of whole-hand mechanical stimuli and grasping kinematics at high spatial, temporal resolution; RA2: Data-driven modeling of stimulus propagation, subspace pattern analysis, and sensorimotor contingencies; and RA3: Engineering and perceptual evaluation of novel wearable haptic interfaces for whole hand interaction.

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OFFICE OF NAVAL RESEARCH Quasiperiodicity, Interactions, and Topology in Tunable Quantum Materials 07/15/2014-05/14/2018 Award #: N00014-14-1-0805; N00014-16-1-2225 $586,300

PI: David Weld, Physics

Quasiperiodicity is at the root of numerous important phenomena in condensed matter physics, from the quantum Hall effect to topological insulators to quasicrystals. However, the complex interplay of strong interactions and quasiperiopdicity in quantum systems remains poorly under- stood. This work aims to realize the first fully tunable quasicrystalline quantum material. This artificial material, consisting of ultracold lithium atoms in one-dimensional quasiperiodic optical traps, is predicted to exhibit fractal quantum Hall energy spectra, nontrivial topological states, and special quasicrystalline excitations known as phasons. Experiments on this model system will provide insight into the effect of strong interactions on topological phases, quantum Hall states, and electron-phason coupling in quasicrystals. These experiments will have navally-relevant implications for the control of transport in low- dimensional electronic systems and the design of next-generation quasiperiodic materials.

Problem-based Initiatives for Powerful Engagement and Learning In Naval Engineering and Science (PIPELINES) 10/01/2015-09/30/2018 Award #: N00014-15-1-2438 $443,907

PI: Maria Teresa Napoli, ICB/CSEP Co-PI(s): Diana Jaleh Arya, The Gevirtz School of Education; Bradley Paden, Mechanical Engineering

The Problem-based Initiatives for Powerful Engagement and Learning In Naval Engineering and Science (PIPELINES) program aims to create engineering and science design experiences that engage undergraduate students to Navy Science, Technology, Engineering and Mathematics (STEM) careers and personnel. PIPELINES’s overarching goal is to increase the number of veterans and underrepresented Community College (CC) students, who major in STEM-related subjects and wish to pursue a civil career in the Navy. More specifically, PIPELINES’s goals are to: G1) promote CC veteran and minority students’ proficiency in STEM-related fields to secure their successful transfer to 4-year institutions and degree completion; G2) increase the number of veterans and other underrepresented CC students in STEM disciplines and Naval careers in particular; G3) train a new generation of STEM and Naval professionals, who think critically, communicate effectively, and are able to creatively and innovatively address social and professional challenges; and G4) investigate the factors affecting veteran and minority students’ participation and academic success in STEM, with the goal of identifying and reinforcing practices that support success.

These goals will be accomplished through three program elements: 1) the well-established approach of experiential learning, made possible by our collaboration with the Naval Facilities Engineering Command, Navy Engineering and Expeditionary Warfare Center (NAVFAC EXWC) at Port Hueneme, California. We will engage student participants in real-world Navy STEM problems, and guide them

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through pathways toward Navy STEM employment (Goal 1, 2, 3); 2) an ethnographic exploration that will make visible STEM-related thinking with particular emphasis on science and engineering applications. Supports for and constraints on students’ (especially veteran students’) progress toward engineering degrees will be foregrounded in this ethnographic approach (Goal 1, 2, 4); and 3) an Applied Innovation and Creativity (AIC) course that uses the entrepreneurship model to support students in developing creativity, innovation, and the ability to execute a plan (Goal 1, 2, 3). PIPELINES is a partnership between the Center for Science and Engineering Partnership (CSEP) at the University of California Santa Barbara (UCSB), and NAVFAC EXWC at Port Hueneme.

ROBERT W. DEUTSCH FOUNDATION

The Robert W. Deutsch Foundation Graduate Fellowships 09/01/2013-08/31/2017 Award #: SB140030 $1,001,051

PI: Joann Kuchera-Morin, Music; Media Arts & Technology

The Deutsch Fellows will be embarking on research in software and content development regarding the AlloSphere Research Facility working on both scientific visualization and multimodal representation of big and complex data as well as information visualization and multimodal representation of abstract and complex information, eventually integrating the techniques into a general purpose computational tool. Proof of concept research will focus on materials, quantum mechanics, fluid dynamics, genomics, abstract information and mathematics for the arts and sciences.

Software and hardware system development for the AlloSphere expanding to video walls, desk top and mobile devices will be accomplished while building the computational platform through the proofs of concept.

UC BERKELEY (BASF) Synthesis of Anti-Oxidation Ag Nanowires via Wet Chemistry 04/01/2016-09/30/2017 Award #: 00009154 $166,848

PI: Galen Stucky, Chemistry

The primary goal of this work is to develop new synthesis methods and recipes to create high- performance and long-term stable Ag nanowires as transparent conductors.

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AWARDS ADMINISTERED

UC BERKELEY (UC OFFICE OF THE PRESIDENT)

UC Network Of Sensors for Exotic physics (UC NOSE) 01/01/2016-12/31/2017 Award #: 00009156 $95,922

PI: Ania Jayich, Physics

We propose a massively parallel, multiplexed detection scheme for exotic physics (axions/chameleons/5th forces/etc). In this scheme, a large array of diamond cantilevers can be fabricated on a single chip (Fig. 2(a)) and the motion of each one can be read out using standard interferometric readout8 imaged onto a multipixel CCD camera. Highly sensitive broadband detection is made possible by designing each cantilever to have a slightly different frequency than the others. Higher order flexural modes extend the frequency detection range even further. The proposed frequency range is from ~ kHz up to several 100 MHz. Importantly, this scheme simultaneously probes almost the entire predicted range of the axion particle.

Simultaneous measurements performed at the various NOSE nodes allow for important correlation measurements. With an expected axion Q-factor of 106 and a speed of 10-3 * c, the distance between UCSB and UCB is comparable to the expected coherence length of the axion field and hence correlations will allow for enhanced detection capabilities, and background noise .

UC MULTICAMPUS RESEARCH PROGRAMS AND INITIATIVES (MRPI) UC Consortium for Vascular Mechanics and Mechanobiology 01/01/2017-12/31/2018 Award #: MRI-17-454791 $150,000

PI: Megan Valentine, Mechanical Engineering

We propose to form a consortium of biologists and engineers to investigate how blood vessels know when to grow and shrink, and how can we control these decisions to fight human diseases such as macular degeneration, cardiovascular disease and cancer. Cells in blood vessels experience many mechanical stimuli: fluid stresses at the vessel wall, tension/compression as the heart beats, stresses at the interfaces between neighboring cells and the matrix surrounding them. We know forces play important roles in vascular growth and maintenance, but the ways by which mechanical signals are sensed, processed and converted to biological outputs are not understood. And since these signals are typically generated and processed deep within tissues, manipulation and analysis is nearly impossible.

Thus, to answer this fundamental question, we need new specialized engineering tools to measure cell forces and mechanics, and new biological systems that allow in situ manipulation of living vessels. Our team has exactly the expertise and tools needed to succeed, including a model organism with completely untapped potential for discovery: the marine organism Botryllus schlosseri. Botryllus grows abundantly off the CA coast and we have recently shown it offers unexpected, unique advantages in studying vascular mechanics and signaling. This proposal will both provide new ocean-derived resources

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AWARDS ADMINISTERED

to UC while expanding its already considerable strength in vascular disease and engineering in completely new directions. This combination will provide extraordinary opportunities for training, discovery and innovation, and improved health outcomes to the citizens of CA.

Here, we propose collaborative research projects among the founding consortium members to dissect how cells sense and react to mechanical signals. We will identify reagents and conditions that enhance or suppress responses to better understand how vessels grow and shrink in the context of health and disease. We will provide coupled training in engineering and biology to graduate and undergraduate students, and anticipate that this work will lead to conference presentations, publications, intellectual property development, and future funding opportunities. At the same time, we will expand our consortium to leverage unique CA resources and tackle even more complex questions in human biology through a large-scale Systemwide effort on Vascular Mechanics and Mechanobiology.

California Institute for Quantum Emulation 01/01/2015-12/31/2017 Award #: CA-15-327861 $299,726

PI: David Weld, Physics

We propose to use a MRPI planning grant to explore and develop the groundwork for a UC-wide collaborative effort called the California Institute for Quantum Emulation (CAIQuE). The initial collaboration team encompasses experimental efforts in ions, atoms, and molecules at Berkeley, UCSD, UCLA, and UCSB, and theory groups at UC Irvine, UCSD, and Berkeley. Scientific goals include direct emulation of nonequilibrium quantum systems, tests of quantum thermalization, and tunable quantum simulation of topologically nontrivial materials. Progress toward these goals will generate possible new research directions for UC investigators in fields ranging from materials science to quantum computing. A truly collaborative approach to quantum simulation will put the UC system, and California, at the forefront of this fundamentally and technologically important field.

UC SAN DIEGO (UC MRPI) Tunable Quantum Materials 01/01/2015-12/31/2017 Award #: MR-15-328528 $225,000

PI: Jon Schuller, ECE

Prof. Schuller and his graduate student (Nikita Butakov) will undertake a program constructing electromagnetic metamaterials from "Quantum Tunable Materials" (particularly Vanadium Oxide). The Schuller group will work with thin-films provided by other members of the proposal team. Nanostructures will be fabricated in the UCSB cleanroom using both photolithography and e-beam lithography tools. Infrared electromagnetic properties will be characterized by a custom FTIR micro- spectrometer system located in the Schuller lab. Visible, and Near-IR micro-spectroscopy studies will be performed with a home-built system also located in the Schuller lab. Complementary electromagnetics simulations will accompany the experiments, using both commercial (Lumerical, COMSOL) and custom (Mie theory) software. The graduate student will participate in both experimental (spectroscopy & fabrication) and theoretical efforts. The PI will supervise the graduate student and also perform theoretical investigations.

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AWARDS ADMINISTERED

THE WOLF MUSEUM OF EXPLORATION AND INNOVATION (MOXI)

Participatory Research and Content Engagement Community STEAM Educational Pilot 04/01/2016-06/30/2017 Award #: SB160124 $250,849

PI: Joann Kuchera-Morin, Music; Media Arts & Technology

The AlloSphere Research Group proposes to test curved screen and flat screen technology in the MOXI media theater space to determine which is most effective in creating a unique visual and interactive engagement for community citizen artists-scientists. The ARG will temporarily install the display and test and temporarily install requisite projectors, speakers, and interactive devices (joysticks, kinects, ipads, etc.) to facilitate an interactive and educational demonstration of technology and content. ARG will seek MOXI’s input on the most appropriate tools for MOXI audience interaction.

The ARG will test and demonstrate content, such as the Hydrogen- Like Atom, the Knot, the Tree, and the Mandebulb Equation for the community on the media theater system. The ARG will also also make available the videos—The Human Body Fly Through and the Multi-Centered Hydrogen Bond on the system. The use of the space and temporary installation and demonstration of this content is not only consistent with the university’s public service mission, but it is vital to engaging the community and it also serves to advance the ARGs research on system deployment and interactivity in varying environments.

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FACILITY MAPS

FACILITY MAPS

First Floor Map

Second Floor Map

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FACILITY MAPS

Third Floor Map

Building Location Map

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PUBLICATIONS

PUBLICATIONS CNSI fosters collaborative research across disciplines with both its facilities and administrative resources. The following list reflects articles that acknowledge or affiliate with CNSI, BNL, CSC, or funding sources administered by CNSI, published during fiscal year 2016-2017.

1. Agarwal, V. and H. Metiu, Oxygen Vacancy Formation on α-MoO3 Slabs and Ribbons. Journal of Physical Chemistry C, 2016. 120: p. 19252-19264.

2. Anastasaki, A., et al., End group modification of poly(acrylates) obtained via ATRP: a user guide. Polymer Chemistry, 2017. 8(4): p. 689-697.

3. Arya, D.J. and M.N. Balos, The benefits of ethnographic research in exploring new intervention in STEM higher education programs.

4. Aue, D.B.D.H., The Application of Computational Chemistry to Problems in Mass Spectrometry. 2017.

5. Banerjee, A., J. Lee, and S. Mitragotri, Intestinal mucoadhesive devices for oral delivery of insulin. Bioengineering & Translational Medicine, 2016. 1(3): p. 338-346.

6. Banerjee, A., et al., Role of nanoparticle size, shape and surface chemistry in oral drug delivery. J Control Release, 2016. 238: p. 176-185.

7. Bjaalie, L., et al., Band alignments between SmTiO3, GdTiO3, and SrTiO3. Journal of Vacuum Science & Technology A, 2016. 34: p. 061102.

8. Bjaalie, L., et al., Metal versus insulator behavior in ultrathin SrTiO 3-based heterostructures. Physical Review B, 2016. 94: p. 035115-6.

9. Bocarsly, J.D., et al., A Simple Computational Proxy for Screening Magnetocaloric Compounds. Chemistry of Materials, 2017. 29: p. 1613-1622.

10. Boden, S., et al., A process to fabricate fused silica nanofluidic devices with embedded electrodes using an optimized room temperature bonding technique. Applied Physics Letters, 2017. 110(18): p. 181605.

11. Bradley, D., et al., Resetting predator baselines in coral reef ecosystems. Scientific Reports, 2017. 7.

12. Brady, L.T. and W. van Dam, Spectral-gap analysis for efficient tunneling in quantum adiabatic optimization. Physical Review A, 2016. 94(3): p. 032309.

13. Brady, L.T. and W. van Dam, Discrepancies between asymptotic and exact spectral-gap analyses of quantum adiabatic barrier tunneling. Physical Review A, 2017. 95(5): p. 052350.

14. Brown, S.J., et al., Morphology-dependent optical anisotropies in the n-type polymer P(NDI2OD-T2). Physical Review B, 2016. 94(16): p. 165105.

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PUBLICATIONS

15. Butala, M.M., et al., Local Structure Evolution and Modes of Charge Storage in Secondary Li-FeS2 Cells. Chemistry of Materials, 2017. 29(7): p. 3070-3082.

16. Campas, O. A toolbox to explore the mechanics of living embryonic tissues. in Seminars in cell & developmental biology. 2016. Elsevier.

17. Canabal, J.A., et al., Dispersion Kernels for Water Wave Simulation. Acm Transactions on Graphics, 2016. 35(6): p. 202.

18. Chen, M.-H., et al., Effects of strain on the stability of tetragonal ZrO 2. Physical Review B, 2016. 94: p. 054108.

19. Choi, S., et al., Observation of discrete time-crystalline order in a disordered dipolar many-body system. Nature, 2017. 543(7644): p. 221-225.

20. Coleman, M.S., et al., Convective quenching of field reversals in accretion disc dynamos. Monthly Notices of the Royal Astronomical Society, 2017. 467: p. 2625-2635.

21. Coleman, M.S.B., et al., Dwarf nova outbursts with magnetorotational turbulence. Monthly Notices of the Royal Astronomical Society, 2016. 462: p. 3710-3726.

22. Collino, R.R., et al., Deposition of ordered two-phase materials using microfluidic print nozzles with acoustic focusing. Extreme Mechanics Letters, 2016. 8: p. 96-106.

23. Csordas, A.T., et al., High-Throughput Discovery of Aptamers for Sandwich Assays. Anal Chem, 2016. 88(22): p. 10842-10847.

24. Dally, R., et al., Floating zone growth of α-Na 0.90 MnO 2 single crystals. Journal of Crystal Growth, 2017. 459: p. 203-208.

25. Das, S., et al., Molecularly Smooth Self-Assembled Monolayer for High-Mobility Organic Field-Effect Transistors. Nano Letters, 2016. 16: p. 6709-6715.

26. Das, T. and J.A. Schuller, Dark modes and field enhancements in dielectric dimers illuminated by cylindrical vector beams. Physical Review B, 2017. 95: p. 201111.

27. Das, T. and J.A. Schuller, Dark modes and field enhancements in dielectric dimers illuminated by cylindrical vector beams. Physical Review B, 2017. 95(20): p. 201111.

28. de Rutte, J., et al., Channel deformation in electrokinetic micro/nanofluidic systems. 2016.

29. DeCrescent, R.A., et al., Model-blind characterization of thin-film optical constants with momentum- resolved reflectometry. Opt Express, 2016. 24(25): p. 28842-28857.

30. Del Bonis-O'Donnell, J.T., et al., A universal design for a DNA probe providing ratiometric fluorescence detection by generation of silver nanoclusters. Nanoscale, 2016. 8(30): p. 14489-96.

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PUBLICATIONS

31. Delaney, K.T. and G.H. Fredrickson, Recent Developments in Fully Fluctuating Field-Theoretic Simulations of Polymer Melts and Solutions. Journal of Physical Chemistry B, 2016. 120: p. 7615-7634.

32. Delaney, K.T. and G.H. Fredrickson, Theory of polyelectrolyte complexation-Complex coacervates are self-coacervates. The Journal of Chemical Physics, 2017. 146: p. 224902.

33. DeMartini, D.G., et al., A cohort of new adhesive proteins identified from transcriptomic analysis of mussel foot glands. Journal of The Royal Society Interface, 2017. 14: p. 20170151.

34. Detrixhe, M. and F. Gibou, Hybrid Massively Parallel Fast Sweeping Method for Static Hamilton- Jacobi Equations. Journal of Computational Physics, 2016. 322: p. 199-223.

35. Discekici, E.H., et al., Light-Mediated Atom Transfer Radical Polymerization of Semi-Fluorinated (Meth)acrylates: Facile Access to Functional Materials. J Am Chem Soc, 2017. 139(16): p. 5939-5945.

36. Discekici, E.H., et al., Dual-pathway chain-end modification of RAFT polymers using visible light and metal-free conditions1. Chem. Commun, 2017. 53: p. 1888-1891.

37. Do, T.N. and Y. Visell, Stretchable, Twisted Conductive Microtubules for Wearable Computing, Robotics, Electronics, and Healthcare. Sci Rep, 2017. 7(1): p. 1753.

38. Doan-Nguyen, V.V.T., et al., Molybdenum Polysulfide Chalcogels as High-Capacity, Anion-Redox- Driven Electrode Materials for Li-Ion Batteries. Chemistry of Materials, 2016. 28(22): p. 8357-8365.

39. Eschmann, N.A., et al., Signature of an aggregation-prone conformation of tau. Scientific Reports, 2017. 7: p. 44739.

40. Evans, H.A., et al., Mono- and Mixed-Valence Tetrathiafulvalene Semiconductors (TTF)BiI4 and (TTF)4BiI6 with 1D and 0D Bismuth-Iodide Networks. Inorg Chem, 2017. 56(1): p. 395-401.

41. Fabini, D.H., et al., Main-Group Halide Semiconductors Derived from Perovskite: Distinguishing Chemical, Structural, and Electronic Aspects. Inorg Chem, 2017. 56(1): p. 11-25.

42. Fabini, D.H., et al., Dynamic Stereochemical Activity of the Sn2+ Lone Pair in Perovskite CsSnBr3. Journal of the American Chemical Society, 2016. 138: p. 11820-11832.

43. Fleischmann, C., et al., Direct Access to Functional (Meth)Acrylate Copolymers Through Transesterification with Lithium Alkoxides. Journal of Polymer Science Part a-Polymer Chemistry, 2017. 55(9): p. 1566-1574.

44. Fong, F.Y., et al., In Vitro Selection of pH-Activated DNA Nanostructures. Angew Chem Int Ed Engl, 2016. 55(49): p. 15258-15262.

45. Ford, M.J., et al., Carrier-Selective Traps: A New Approach for Fabricating Circuit Elements with Ambipolar Organic Semiconductors. Advanced Electronic Materials, 2017. 3(3).

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PUBLICATIONS

46. Forman, C., et al., Semipolar (202̅1) III-Nitride P-Down LEDs with in situ anneal to reduce the Mg memory effect. Journal of Crystal Growth, 2017. 464: p. 197-200.

47. Friedrich, L., et al., Acoustic control of microstructures during direct ink writing of two-phase materials. Sensors and Actuators A: Physical, 2017.

48. Friedrich, L., et al. Scaling Relationships for Direct Ink Writing with Acoustic Focusing. in TMS 2017 146th Annual Meeting & Exhibition Supplemental Proceedings. 2017. Springer.

49. Fronk, S.L., et al., Effect of chiral 2-ethylhexyl side chains on chiroptical properties of the narrow bandgap conjugated polymers PCPDTBT and PCDTPT. Chemical Science, 2016. 7: p. 5313-5321.

50. Ganguly, P., N.F. van der Vegt, and J.-E. Shea, Hydrophobic Association in Mixed Urea-TMAO Solutions. Journal of Physical Chemistry Letters, 2016. 7: p. 3052-3059.

51. Garcia, E.S., C.L. Tague, and J.S. Choate, Uncertainty in carbon allocation strategy and ecophysiological parameterization influences on carbon and streamflow estimates for two western US forested watersheds. Ecological Modelling, 2016. 342: p. 19-33.

52. Garcia, M. and S. Pennathur, Inertial particle dynamics in the presence of a secondary flow. Physical Review Fluids, 2017. 2(4): p. 042201.

53. Garrison, J.R., R.V. Mishmash, and M.P.A. Fisher, Partial breakdown of quantum thermalization in a Hubbard-like model. Phys. Rev. B, 2017. 95: p. 054204.

54. Goiri, J.G. and A. Van der Ven, Phase and structural stability in Ni-Al systems from first principles. Physical Review B, 2016. 94: p. 14.

55. Goldhaber, D. and R. Startz, On the Distribution of Worker Productivity: The Case of Teacher Effectiveness and Student Achievement. Statistics and Public Policy, 2016. 4.

56. Gotrik, M.R., et al., Advancements in Aptamer Discovery Technologies. Acc Chem Res, 2016. 49(9): p. 1903-10.

57. Guo, H. and X. Yang, Polynomial preserving recovery for high frequency wave propagation. Journal of Scientific Computing, 2017. 71: p. 594-614.

58. Gutekunst, W.R., et al., Practical Chain-End Reduction of Polymers Obtained with ATRP. Macromolecular Chemistry and Physics, 2017.

59. Haitjema, C.H., et al., A parts list for fungal cellulosomes revealed by comparative genomics. Nat Microbiol, 2017. 2: p. 17087.

60. Hemmer, J.R., et al., Tunable Visible and Near Infrared Photoswitches. J Am Chem Soc, 2016. 138(42): p. 13960-13966.

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PUBLICATIONS

61. Himmetoglu, B., Tree based machine learning framework for predicting ground state energies of molecules. Journal of Chemical Physics, 2016. 145: p. 9.

62. Huang, D., et al., Dynamically reconfigurable integrated optical circulators. Optica, 2017. 4: p. 23-30.

63. Huang, D., et al., Electrically Driven and Thermally Tunable Integrated Optical Isolators for Silicon Photonics. IEEE Journal of Selected Topics in Quantum Electronics, 2016. 22: p. 4403408.

64. Hyatt, K., et al., Many-body localization in the presence of a small bath. Physical Review B, 2017. 95: p. 035132.

65. Iyer, P.P., M. Pendharkar, and J.A. Schuller, Electrically Reconfigurable Metasurfaces Using Heterojunction Resonators. Advanced Optical Materials, 2016.

66. Jayich, A.M., X. Long, and W.C. Campbell, Direct Frequency Comb Laser Cooling and Trapping. Physical Review X, 2016. 6(4): p. 041004.

67. Johnson, K.M. and G.E. Hofmann, A transcriptome resource for the Antarctic pteropod Limacina helicina antarctica. Marine Genomics, 2016. 28: p. 25-28.

68. Joswiak, M.N., M.F. Doherty, and B. Peters, Critical length of a one-dimensional nucleus. Journal of Chemical Physics, 2016. 145: p. 6.

69. Kang, Y., et al., Fundamental limits on the electron mobility of ß-Ga2O3. Journal of Physics: Condensed Matter, 2017. 29: p. 234001.

70. Karam, P.R., A. Dukhin, and S. Pennathur, Optimal MEMS device for mobility and zeta potential measurements using DC electrophoresis. Electrophoresis, 2017. 38(9-10): p. 1245-1250.

71. Kim, B., et al., Aggregation of Chameleon Peptides: Implications of a-Helicity in Fibril Formation. Journal of Physical Chemistry B, 2016. 120: p. 5874-5883.

72. Kim, S., et al., Order-disorder transition in thin films of horizontally-oriented cylinder-forming block copolymers: thermal fluctuations vs. preferential wetting. Soft Matter, 2016. 12: p. 5915-5925.

73. Kirchhofer, N.D., et al., A Ferrocene-Based Conjugated Oligoelectrolyte Catalyzes Bacterial Electrode Respiration. Chem, 2017. 2: p. 240-257.

74. Ko, J.S., et al., Na2Ti3O7 Nanoplatelets and Nanosheets Derived from a Modified Exfoliation Process for Use as a High-Capacity Sodium-Ion Negative Electrode. Acs Applied Materials & Interfaces, 2017. 9(2): p. 1416-1425.

75. Kohler, J., et al., Cavity-Assisted Measurement and Coherent Control of Collective Atomic Spin Oscillators. Phys Rev Lett, 2017. 118(6): p. 063604.

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PUBLICATIONS

76. Krishnaswamy, K., et al., First-principles analysis of electron transport in BaSnO 3. Physical Review B, 2017. 95: p. 205202.

77. Kristoffersen, H.H., et al., Stability of V2O5 Supported on Titania in the Presence of Water, Bulk Oxygen Vacancies, and Adsorbed Oxygen Atoms. The Journal of Physical Chemistry C, 2017. 121: p. 8444-8451.

78. Labram, J.G., et al., Charge transport in a two-dimensional hybrid metal halide thiocyanate compound. Journal of Materials Chemistry C, 2017. 5(24): p. 5930-5938.

79. Lamontagne, L.K., et al., The Role of Structural and Compositional Heterogeneities in the Insulator- to-Metal Transition in Hole-Doped APd3O4 (A= Ca, Sr). Inorganic Chemistry, 2017. 56: p. 5158-5164.

80. Lee, D., et al., Topical Review: Spins and mechanics in diamond. Journal of Optics, 2017. 19(3): p. 033001.

81. Lee, K.W., et al., Strain Coupling of a Mechanical Resonator to a Single Quantum Emitter in Diamond. Physical Review Applied, 2016. 6(3): p. 034005.

82. Levine, Z.A. and J.-E. Shea, Simulations of disordered proteins and systems with conformational heterogeneity. Current Opinion in Structural Biology, 2017. 43: p. 95-103.

83. Lewi, T., et al., Ultrawide Thermo-Optic Tuning of PbTe Meta-atoms. Nano Letters, 2017.

84. Lewi, T., et al. Widely tunable infrared semiconductor Mie resonators. in Proc. SPIE 9918, Metamaterials, Metadevices, and Metasystems. 2016. San Diego, CA: SPIE.

85. Li, B., et al., Assemblies of Microfluidic Channels and Micropillars Facilitate Sensitive and Compliant Tactile Sensing. Ieee Sensors Journal, 2016. 16(24): p. 8908-8915.

86. Liu, E.E., et al., Ligand-Induced Variations in Symmetry and Structural Dimensionality of Lead Oxide Carboxylates. Crystal Growth & Design, 2017. 17: p. 1574-1582.

87. Liu, J., K.T. Delaney, and G.H. Fredrickson. Optimized phase field models in confinement: fast and accurate simulations of directed self-assembly. in SPIE Advanced Lithography. 2017. International Society for Optics and Photonics.

88. Loessberg-Zahl, J., et al., (Almost) Stationary Isotachophoretic Concentration Boundary in a Nanofluidic Channel Using Charge Inversion. Analytical Chemistry, 2016. 88(12): p. 6145-6150.

89. Luo, Y., et al., Improved self-assembly of poly (dimethylsiloxane-b-ethylene oxide) using a hydrogen- bonding additive. Journal of Polymer Science Part A: Polymer Chemistry, 2016. 54(14): p. 2200-2208.

90. Lyons, J.L. and C.G. Van de Walle, Computationally predicted energies and properties of defects in GaN. NPJ Computational Materials, 2017. 3: p. 1.

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PUBLICATIONS

91. Mage, P., et al., Closed-loop control of circulating drug levels in live animals. Nature Biomedical Engineering, 2017. 1: p. 0070.

92. Martin, J.M., et al., Statistical field theory description of inhomogeneous polarizable soft matter. Journal of Chemical Physics, 2016. 145: p. 154104.

93. McDearmon, B., et al., Synthesis of a versatile pentacyclic building block for organic electronics. Journal of Polymer Science Part A: Polymer Chemistry, 2017. 55: p. 2618-2628.

94. McIntosh, C., et al., Olive oil density characterization through microfluidic detection using acoustic signatures (MIDAS). Analytical Methods, 2016. 8(42): p. 7673-7677.

95. Miao, M., et al., Inner-shell chemistry under high pressure. Japanese Journal of Applied Physics, 2017. 56: p. 05-10.

96. Miao, M.-S., et al., Quasimolecules in Compressed Lithium. Angewandte Chemie, 2017. 129: p. 992- 995.

97. Myers, B.A., A. Ariyaratne, and A.C.B. Jayich, Double-Quantum Spin-Relaxation Limits to Coherence of Near-Surface Nitrogen-Vacancy Centers. Phys Rev Lett, 2017. 118(19): p. 197201.

98. Natarajan, A.R. and A. Van der Ven, First-principles investigation of phase stability in the Mg-Sc binary alloy. Physical Review B, 2017. 95: p. 214107.

99. Natarajan, A.R. and A. Van der Ven, A unified description of ordering in HCP Mg-RE alloys. Acta Materialia, 2017. 124: p. 620-632.

100. Niu, J., et al., Engineering live cell surfaces with functional polymers via cytocompatible controlled radical polymerization. Nat Chem, 2017. 9(6): p. 537-545.

101. Oschmann, B., et al., Effects of Tailored Dispersity on the Self-Assembly of Dimethylsiloxane- Methyl Methacrylate Block Co-Oligomers. Acs Macro Letters, 2017. 6(7): p. 668-673.

102. Page, Z.A., et al., A di-tert-butyl acrylate monomer for controlled radical photopolymerization. Journal of Polymer Science Part A: Polymer Chemistry, 2017. 55(5): p. 801-807.

103. Page, Z.A., et al., Novel Strategy for Photopatterning Emissive Polymer Brushes for Organic Light Emitting Diode Applications. ACS Cent Sci, 2017. 3(6): p. 654-661.

104. Pan, L., et al., Phase diagram of the frustrated asymmetric ferromagnetic spin ladder. The European Physical Journal B, 2017. 90: p. 105.

105. Peelaers, H., M.L. Chabinyc, and C.G. Van de Walle, Controlling n-Type Doping in MoO3. Chemistry of Materials, 2017. 29: p. 2563-2567.

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PUBLICATIONS

106. Peng, X.F., S.P. Gilmore, and M.A. O'Malley, Microbial communities for bioprocessing: lessons learned from nature. Current Opinion in Chemical Engineering, 2016. 14: p. 103-109.

107. Pintus, P., et al., Microring-based Optical Isolator and Circulator with Integrated Electromagnet for Silicon Photonics. Journal of Lightwave Technology, 2017.

108. Qu, H., et al., Rapid and Label-Free Strategy to Isolate Aptamers for Metal Ions. ACS Nano, 2016. 10(8): p. 7558-65.

109. Radin, M.D. and A. Van der Ven, Stability of Prismatic and Octahedral Coordination in Layered Oxides and Sulfides Intercalated with Alkali and Alkaline-Earth Metals. Chemistry of Materials, 2016. 28: p. 7898-7904.

110. Rajan, N.K., et al., A simple microfluidic aggregation analyzer for the specific, sensitive and multiplexed quantification of proteins in a serum environment. Biosens Bioelectron, 2016. 77: p. 1062-9.

111. Ruhe, Z.C., et al., CdiA Effectors Use Modular Receptor-Binding Domains To Recognize Target Bacteria. Mbio, 2017. 8(2): p. e00290-17.

112. Saha, K., Photoinduced Chern insulating states in semi-Dirac materials. Physical Review B, 2016. 94(8): p. 081103.

113. Sen, A.D.J.P. and T. Kim, Compressing Fluid Subspaces.

114. Serwane, F., et al., In vivo quantification of spatially varying mechanical properties in developing tissues. Nat Methods, 2017. 14(2): p. 181-186.

115. Shi, N., et al., Diffusiophoretic Focusing of Suspended Colloids. Phys Rev Lett, 2016. 117(25): p. 258001.

116. Siouri, F.M., et al., Excited State Dynamics of 6-Thioguanine. The Journal of Physical Chemistry A, 2017.

117. Slagle, K., et al., Out-of-time-order correlation in marginal many-body localized systems. Physical Review B, 2017. 95: p. 165136.

118. Stock, P., et al., Unraveling Hydrophobic Interactions at the Molecular Scale Using Force Spectroscopy and Molecular Dynamics Simulations. ACS nano, 2017. 11: p. 2586-2597.

119. Su, G.M., et al., First-Principles Predictions of Near-Edge X-ray Absorption Fine Structure Spectra of Semiconducting Polymers. The Journal of Physical Chemistry C, 2017. 121: p. 9142-9152.

120. Tailor, H.D., et al., Impact of nitrogen and carbon on defect equilibrium in ZrO 2. Acta Materialia, 2016. 117: p. 286-292.

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PUBLICATIONS

121. Tang, X., et al., Partitioned Similarity Search with Cache-Conscious Data Traversal. ACM Transactions on Knowledge Discovery from Data (TKDD), 2017. 11: p. 34.

122. Teng, Y., D.I.W. Levin, and T. Kim, Eulerian Solid-Fluid Coupling. Acm Transactions on Graphics, 2016. 35(6): p. 200.

123. Tree, D.R., et al., A multi-fluid model for microstructure formation in polymer membranes. Soft Matter, 2017. 13: p. 3013-3030.

124. Truong, N.P., et al., Surfactant-free RAFT emulsion polymerization using a novel biocompatible thermoresponsive polymer. Polymer Chemistry, 2017. 8(8): p. 1353-1363.

125. Tsai, C.L., K.T. Delaney, and G.H. Fredrickson, Genetic Algorithm for Discovery of Globally Stable Phases in Block Copolymers. Macromolecules, 2016. 49: p. 6558-6567.

126. Ulrich, S., et al., Visible Light-Responsive DASA-Polymer Conjugates. Acs Macro Letters, 2017. 6(7): p. 738-742.

127. Vinckeviciute, J., M.D. Radin, and A. Van der Ven, Stacking-sequence changes and Na ordering in layered intercalation materials. Chemistry of Materials, 2016. 28: p. 8640-8650.

128. Wang, J., et al., Multiparameter Particle Display (MPPD): A Quantitative Screening Method for the Discovery of Highly Specific Aptamers. Angew Chem Int Ed Engl, 2017. 56(3): p. 744-747.

129. Wang, M., et al., Hole Mobility and Electron Injection Properties of D-A Conjugated Copolymers with Fluorinated Phenylene Acceptor Units. Advanced Materials, 2017. 29.

130. Wang, S.M., et al., Ultrafast photo-induced dynamics across the metal-insulator transition of VO2. Epl, 2017. 118(2).

131. Wang, W., A. Janotti, and C.G. Van de Walle, Phase transformations upon doping in WO3. The Journal of Chemical Physics, 2017. 146: p. 214504.

132. Wei-Cheng, L. and W. Congjun, Microscopic Theory of the Thermodynamic Properties of Sr3Ru2O

7. Chinese Physics Letters, 2016. 33(03): p. 37201-037201.

133. Weston, L., et al., Acceptor doping in the proton conductor SrZrO 3. Physical Chemistry Chemical Physics, 2017. 19: p. 11485-11491.

134. Whitfield, R., et al., Universal Conditions for the Controlled Polymerization of Acrylates, Methacrylates, and Styrene via Cu(0)-RDRP. J Am Chem Soc, 2017. 139(2): p. 1003-1010.

135. Xulvi-Brunet, R., et al., Computational analysis of fitness landscapes and evolutionary networks from in vitro evolution experiments. Methods, 2016. 106: p. 86-96.

136. Yan, L., et al., Architecture and coevolution of allosteric materials. Proceedings of the National

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PUBLICATIONS

Academy of Sciences, 2017: p. 201615536.

137. Yu, D., S.C. Feinstein, and M.T. Valentine, Effects of wild type tau and disease-linked tau mutations on microtubule organization and intracellular trafficking. J Biomech, 2016. 49(8): p. 1280- 1285.

138. Zhang, J., et al., Observation of a discrete time crystal. Nature, 2017. 543(7644): p. 217-+.

139. Zhu, Z., H. Peelaers, and C.G. Van de Walle, Hydrogen intercalation in MoS 2. Physical Review B, 2016. 94: p. 085426.

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STATISTICAL SUMMARY

2016-2017 STATISTICAL SUMMARY

1. Academic personnel engaged in research: a. Faculty 56 b. Professional Researchers (including Visiting) 3 c. Project Scientists 2 d. Specialists 7 e. Postdoctoral Scholars/Postgraduate Researchers 30 f. CSEP Faculty Participants 120+

2. Graduate Students: a. Employed on contracts and grants 67 b. Employed on other sources of funds 46 c. Participating through assistantships/traineeships 50 d. Fellowships and non-payroll e. CSEP graduate student and postdoc participants 1,400+

3. Undergraduate Students: a. Employed on contracts and grants 19 b. Employed on other sources of funds 40 c. CSEP program participants 730+

4. Participation from outside UCSB: a. Academics (without Salary Academic Visitors) 3 b. CSEP K-12 and community participants 9,600+ c. CSEP community college students 30+ d. Other – High School Students 9,600+ e. Other – Industry Speakers/Mentors/Volunteers 170+ e. Other – Professionals On and Off-Campus 150+

5. Staff (Univ. & Non-Univ. Funds): a. Technical 6 b. Administrative/Clerical 9 c. Academic Coordinators 8

6. Seminars, symposia, workshops, & events sponsored 381

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STATISTICAL SUMMARY

7. Proposals Submitted 50

8. Number of different awarding agencies engaged 26

9. Number of extramural awards administered 44

10. Dollar value of extramural awards administered $25,350,211

11. Number of Principal Investigators 70

12. Dollar value of other project awards $1,210,000

13. Number of other projects administered 1

14. Total base budget for the year (as of June 30, 2017) $2,591,387

15. Dollar value of intramural support $456,811

16. Dollar value of awards for year $5,784,967

17. Total assigned square footage in CNSI 64,221

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ADVISORY COMMITTEE AND

STAFFING

ADVISORY COMMITTEE AND STAFFING

Advisory Committee Alferness, Rod Dean, College of Engineering Hawker, Craig Director, CNSI Incandela, Joseph Vice Chancellor for Research Margalith, Tal Executive Director of Technology, CNSI Read de Alaniz, Javier Associate Director, CNSI Valentine, Megan Associate Director, CNSI Wilson, Stephen Associate Director, CNSI Wiltzius, Pierre Dean of Science, College of Letters & Science Woo, Holly Assistant Director , CNSI

Administrative Staff Ajao, Jessica Contracts and Grants Analyst Daniels, Daniel R. Purchasing Coordinator Deloa, Eva Financial Manager Guillén, Marissa Special Projects Analyst Henry, Jessica Events and Visitor Coordinator/Administrative Analyst Kang, Susan N. Administrative Assistant to Professor Heeger Leininger, Lynne Financial Assistant Perez, Sonya M. Academic Personnel Coordinator Thomas, Theodore E. Financial Analyst Woo, Holly L. Assistant Director

Center for Science and Engineering Partnership Staff Aguirre, M. Ofelia CSEP Director Davis, Samantha Undergraduate Research Programs Coordinator Ibsen, Wendy S. CSEP Associate Director Lenaburg, Lubi Evaluation and Assessment Program Manager Lubin, Arica A. Professional Development Program Manager Mendes, Stephanie Early Research Experiences Coordinator Napoli, Maria T. Community College Programs Coordinator Sciaky, Ellie Evaluation Coordinator

Technical Staff Bothman, David Peter Microfluidics Lab Manager Smith, Jen Biological Nanostructures Lab Manager Hanson, Robert K. Building Manager Margalith, Tal Executive Director of Technology Sawyer, Randal L. Cleanroom Manager Weakliem, Paul C. Information Technology Director

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PRINCIPAL INVESTIGATORS

PRINCIPAL INVESTIGATORS

Last Name First Name Title Home Department Abu-Omar Mahdi Professor Chemistry and Biochemistry Aguirre M. Ofelia Director, CSEP CNSI Arya Diana Assistant Professor Gevirtz School of Education Atzberger Paul Professor Mathematics Awschalom David Professor Physics Brown Frank Professor Chemistry and Biochemistry Butler Alison Professor Chemistry and Biochemistry Campas-Rigau Otger Assistant Professor Mechanical Engineering Carlson Jean Professor Physics Castellanos Mario Executive Director Office of Education Partnerships Chabinyc Michael Professor Materials De Tomaso Anthony Associate Professor Molecular, Cellular and Dev. Biology Doherty Michael Professor Chemical Engineering Doyle Adele Assistant Researcher Neuroscience Research Institute Ford Peter Professor Chemistry and Biochemistry Fredrickson Glenn Professor Materials; Chemical Engineering Garcia-Cervera Carlos Professor Mathematics Gibou Frederic Professor Mechanical Engineering Gordon Michael Associate Professor Chemical Engineering Gwinn Elisabeth Professor Physics Harlow Danielle Associate Professor Gevirtz School of Education Hawker Craig Professor Chemistry and Biochemistry & Materials Heeger Alan Professor Chemistry and Biochemistry & Physics Holden Patricia Professor Bren School of Env. Science & Mgmt. Jayich Ania Professor Physics Keller Arturo Professor Bren School of Env. Science & Mgmt. Khankhel Aimal Graduate Student Biomolecular Sci and Engineering Kim Theodore Assistant Professor Media Arts and Technology Knight Abigail Postdoc CNSI Kosik Kenneth Professor Molecular, Cellular and Dev. Biology Kuchera-Morin Joann Professor Music; Media Arts & Technology Legrady George Professor Media Arts & Technology Program Little Raymond Professor Chemistry and Biochemistry Martinis John Professor Physics Napoli Maria Academic Coordinator CNSI O'Malley Michelle Assistant Professor Chemical Engineering Paden Bradley Professor Mechanical Engineering

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PRINCIPAL INVESTIGATORS

Last Name First Name Title Home Department Pennathur Sumita Associate Professor Mechanical Engineering Plantinga Andrew Professor Bren School of Env. Science & Mgmt. Read de Alaniz Javier Associate Professor Chemistry and Biochemistry Rothman Joel Professor Molecular, Cellular and Dev. Biology Schuller Jon Assistant Professor Electrical and Computer Engineering Scida Karen Postdoc CNSI Scott Susannah Professor Chemical Engineering Seshadri Ram Professor Materials Sherwood Tim Professor Computer Science Stemmer Susanne Professor Materials Strukov Dmitri Professor Electrical and Computer Engineering Stucky Galen Professor Chemistry and Biochemistry Suh Sangwon Associate Professor Bren School of Env. Science & Mgmt. Susko Tyler Lecturer PSOE Mechanical Engineering Szumlinski Karen Professor Psychological and Brain Sciences Valentine David Professor Department of Earth Science Valentine Megan Associate Professor Mechanical Engineering van Dam Willem Associate Professor Computer Science Van de walle Christian Professor Materials Electrical and Computer Engineering; Visell Yon Assistant Professor Media Arts & Technology Weld David Assistant Professor Physics Wilson Stephen Associate Professor Materials Xie Yuan Professor Electrical and Computer Engineering York Robert Professor Electrical and Computer Engineering Young Andrea Assistant Professor Physics

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