Visualization of the earliest steps of gammadelta T cell development in the adult thymus. Prinz, I., Sansoni, A., Kissenpfennig, A., Ardouin, L., Malissen, M., & Malissen, B. (2006). Visualization of the earliest steps of gammadelta T cell development in the adult thymus. Nature Immunology, 7(9)(9), 995-1003. https://doi.org/10.1038/ni1371 Published in: Nature Immunology Document Version: Early version, also known as pre-print Queen's University Belfast - Research Portal: Link to publication record in Queen's University Belfast Research Portal General rights Copyright for the publications made accessible via the Queen's University Belfast Research Portal is retained by the author(s) and / or other copyright owners and it is a condition of accessing these publications that users recognise and abide by the legal requirements associated with these rights. Take down policy The Research Portal is Queen's institutional repository that provides access to Queen's research output. Every effort has been made to ensure that content in the Research Portal does not infringe any person's rights, or applicable UK laws. If you discover content in the Research Portal that you believe breaches copyright or violates any law, please contact
[email protected]. Download date:28. Sep. 2021 ARTICLES Visualization of the earliest steps of cd T cell development in the adult thymus Immo Prinz1, Amandine Sansoni1, Adrien Kissenpfennig1,2, Laurence Ardouin1, Marie Malissen1 & Bernard Malissen1 The checkpoint in cd cell development that controls successful T cell receptor (TCR) gene rearrangements remains poorly characterized. Using mice expressing a reporter gene ‘knocked into’ the Tcrd constant region gene, we have characterized many of the events that mark the life of early cd cells in the adult thymus.