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Study Publication Date: May 2000 Freedonia Study #1264 Price: $4,500 Pages: 218 World Amino Acids

World Amino Acids, a new study from The Freedonia Group, is designed to provide you with an in-depth analysis of the major trends in the world market for amino acids and the outlook for product segments and major markets -- critical information to help you with strategic planning.

This brochure gives you an indication of the scope, depth and value of Freedonia's new study, World Amino Acids. Ordering information is included on the back page of the brochure.

Brochure Table of Contents

Study Highlights ...... 2 Study Table of Contents and List of Tables and Charts ...... 4 Sample Pages and Tables from: Market Environment...... 6 World Demand ...... 7 Supply and Demand by Country & Region ...... 8 Industry Structure ...... 9 Company Profiles ...... 10 List of Companies Profiled ...... 11 Forecasting Methodology ...... 12 About the Company ...... 13 Advantages of Freedonia Reports ...... 13 About Our Customers ...... 14 Related Studies ...... 15 Ordering Information...... 16 Study Highlights World Highlights

• World demand for amino acids is projected to ad- vance 5.6 percent per annum to $7.5 billion in 2004.

• Animal feed additives are expected to be the leading category of products as livestock breeders around the globe seek to reduce input costs.

• Among products consumed by humans, trends toward healthier, active lifestyles, coupled with strong incentives promoting preventive medicine, will lead to an expanding market for dietary supplements and nutritional products containing amino acids.

• The Asia/Pacific region will continue to be the leader in amino acid production and consumption, largely due to the enormous size of the MSG market in that part of the world.

Industry Structure

• The global amino acids industry consists of large diversified companies, fine chemical producers with commanding positions in one or a few markets, and specialized firms that produce small-volume, value- added products for pharmaceuticals and other high- end markets.

* Amino acids are components that serve as ingredients • Leading players include Anjinomoto, Degussa-Huels, of animal feeds, foods and beverages, dietary supplements, Aventis, Novus International and Kyowa Hakko cosmetics and various specialized preparations (e.g., meal Kogyo; these five participants held slightly more than substitutes, enteral feeding preparations and parenteral nutri- tional solutions). Specific types examined include , 50 percent of the world market in 1999. methionine, glutamic acid and . Historical data (1989, 1994, 1999) and forecasts to 2004 and 2009 are provided for amino acids by type and end-use application. Trade data are provided on a regional basis. For the purposes of this study, the term “livestock” refers to cattle, swine and poultry.

World Amino Acids #1264 Freedonia Industry Study 2 Study Highlights World Amino Acids Demand by Region, 1999 (million dollars)

North America Europe 29.1% 20.7%

Other World 9.9%

Asia/Pacific 40.3%

World Amino Acids Demand by Product (million dollars) % Annual Growth Item 1994 1999 2004 2009 99/94 04/99

World Population (mil persons) 5180 5988 6337 6694 1.5 1.1 $ amino acids/capita 0.73 0.95 1.18 1.45 -- --

World GDP (bil US97$) 26801 35520 42180 50840 2.9 3.5 $ amino acids/000$ GDP 0.14 0.16 0.18 0.19 -- --

Amino Acids Demand 3775 5680 7455 9735 4.2 5.6

By Product: Sample Table Glutamic Acid 1540 1788 2130 2546 1.5 3.6 Methionine 838 1415 1797 2298 5.4 4.9 Lysine 484 737 1200 1800 4.3 10.2 Phenylalanine 461 696 853 1055 4.2 4.2 Other 452 1044 1475 2036 8.7 7.2

$/lb 1.26 1.22 1.28 1.34 -0.3 1.0 Amino Acids Demand (mil lbs) 2985 4665 5820 7240 4.6 4.5

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World Amino Acids #1264 Order form on last page 3 I. EXECUTIVE SUMMARY Table of Contents Summary Table ...... 3 II. MARKET ENVIRONMENT General ...... 4 Global Economic Overview ...... 5 Table - World Macroeconomic Outlook ...... 6 Tables and Charts are featured for each region and Economic Factors...... 6 country. Historical data and forecasts are presented Table - World Gross Domestic Product for 1994, 1999, 2004 and 2009. by Region & Country ...... 9 Demographic Trends ...... 10 Table - World Population by Region & Country ...... 11 Global Food & Beverage Industry Outlook ...... 12 Tables for each region and country, Table - World Food & Beverage Shipments ...... 15 the following series are covered: Global Agricultural Industry Overview...... 15 Table - Selected World Agricultural Indicators ...... 17 Global Outlook ...... 17 Population (million persons) Table - World Pharmaceutical Shipments ...... 19 $ amino acids/capita Global Specialty Nutritional Products Outlook ...... 20 Table - World Nutritional Product Shipments...... 21 Amino Acids Demand Dietary Supplements ...... 21 By Product: Other Specialty Nutritional Products ...... 22 Glutamic Acid Regulatory Considerations ...... 24 Methionine International Trade...... 27 Lysine Table - Amino Acids: International Trade ...... 29 Phenylalanine Market & Pricing Trends ...... 29 Other Table - World Amino Acids: Market & Pricing Trends ....31

By Country/Region III. WORLD DEMAND General ...... 32 + net exports World Amino Acids Demand by Region ...... 32 Table - World Amino Acids Demand by Region ...... 35 Amino Acid Shipments Chart - World Amino Acids Demand by Region, 1999 ..... 36 $/lb. World Amino Acids Demand by Type ...... 36 Amino Acids Demand (million lbs.) Table - World Amino Acids Demand by Type ...... 37 Chart - World Amino Acids Demand by Type, 1999 ...... 37 % Country/Region Demand Glutamic Acid ...... 38 World Amino Acids Demand (million $) Table - World Glutamic Acid Demand ...... 40 Methionine ...... 41 Table - World Methionine Demand ...... 44 Lysine ...... 44 Table - World Lysine Demand...... 47 Phenylalanine ...... 47 Table - World Phenylalanine Demand ...... 49 Other ...... 49 Table - World Other Amino Acids Demand ...... 53 World Amino Acids Demand by Market ...... 53 Table - World Amino Acids Demand by Market ...... 54 Chart - World Amino Acids Demand by Market, 1999 .... 55 Food & Beverage ...... 55 Table - Amino Acids: World Food & Beverage Demand .... 57

World Amino Acids #1264 Freedonia Industry Study 4 Animal Feed ...... 57 Products ...... 115 Table - Amino Acids: World Animal Feed Demand ...... 60 Suppliers ...... 117 Pharmaceuticals & Nutraceuticals ...... 60 Indonesia ...... 118 Table - Amino Acids: World Pharmaceutical Products ...... 119 & Nutraceutical Demand ...... 63 Suppliers ...... 121 Other ...... 63 Japan ...... 121 Table - Amino Acids: World Demand Products ...... 122 in Other Markets...... 66 Suppliers ...... 124 South Korea ...... 124 IV. NORTH AMERICA Products ...... 125 General ...... 67 Suppliers ...... 126 United States ...... 69 Thailand ...... 127 Products ...... 70 Products ...... 129 Suppliers ...... 72 Suppliers ...... 130 Canada ...... 74 Taiwan ...... 130 Products ...... 75 Products ...... 131 Suppliers ...... 76 Suppliers ...... 132 Mexico ...... 77 Vietnam ...... 133 Products ...... 78 Products ...... 134 Suppliers ...... 79 Suppliers ...... 135 Australia ...... 136 V. EUROPE Products ...... 137 General ...... 81 Suppliers ...... 138 Germany ...... 83 Other Asia/Pacific ...... 139 Products ...... 85 Products ...... 140 Suppliers ...... 86 Suppliers ...... 142 France ...... 87 Products ...... 88 VII. OTHER WORLD Suppliers ...... 89 General ...... 143 United Kingdom...... 90 Latin America ...... 144 Products ...... 91 Products ...... 146 Suppliers ...... 93 Suppliers ...... 148 Italy ...... 94 Africa/Mideast ...... 149 Products ...... 95 Products ...... 150 Suppliers ...... 96 Suppliers ...... 151 Spain ...... 98 Products ...... 99 VIII. INDUSTRY STRUCTURE Suppliers ...... 100 General ...... 153 Switzerland ...... 101 Market Share ...... 154 Products ...... 102 Chart - Global Amino Acids Market Share, 1999 ...... 156 Suppliers ...... 103 Marketing & Distribution Factors ...... 156 Other Western Europe ...... 103 Research & Development ...... 158 Products ...... 105 Requirements ...... 159 Suppliers ...... 106 Competitive Strategies ...... 160 Eastern Europe ...... 107 Licensing & Related Agreements ...... 162 Products ...... 108 Table - Selected Cooperative Agreements ...... 163 Suppliers ...... 109 Mergers & Acquisitions ...... 166 Table - Selected Acquisitions & Divestitures ...... 167 VI. ASIA/PACIFIC Table - Amino Acids Sales by Company, 1999...... 168 General ...... 111 Company Profiles ...... 168-218 China ...... 113

World Amino Acids #1264 Order form on last page 5 Market Environment

The Market Environment Section discusses key indicators that drive demand for amino acids, including regulatory considerations, the outlook for specialty nutritional products and Freedonia’s uniquely developed MARKET ENVIRONMENT macroeconomic indicators. Dietary Supplements This information provides you with an understanding and an analysis of the Dietary supplements are a distant second to fortified foods and beverages among all specialty nutritionals. Nevertheless, they warrant their own discussion vis-a-vis climate in which the global amino amino acids because of the opportunities they present for amino acid manufactur- acids industry operates and helps you ers and marketers. build your market strategy to sustain long-term growth. Classified as over-the-counter drugs, homeopathic remedies or alternative medicines, combined global demand for supplemental dietary preparations will reach $31 billionSAMPLE in 2004, up PAGE over eleven percent annually from 1999. Growth will partially reflect an increasing number of individuals with above normal vitamin, mineral and nutrient requirements. More significantly, the rapidly rising popularity of herbal medicines for disease prevention and treatment will greatly broaden overall opportunities. Intensifying competition among suppliers, downward pricing pressures and the tightening of government regulations will inhibit dietary supplements from achieving even faster demand growth worldwide.

Several other factors will impact the dietary supplements market, including:

• heightened health consciousness among aging populations in industrialized nations

• increased interest in self treatment and preventive medicine in countries where health is being pared

• an expanding base of products that are perceived to be beneficial

• entry into the market of large pharmaceutical companies with brandname

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World Amino Acids #1264 Freedonia Industry Study 6 World Demand

The World Demand Section highlights WORLD DEMAND the global amino acid market over the past ten years and summarizes contrib- Animal Feed uting growth factors. Demand for amino acids in animal feed formulations is projected to grow 6.5 This information helps you: percent per annum to 2.4 billionSAMPLE pounds in 2004,PAGE valued billion. Over the next decade, revenues in this segment will be accounted for almost entirely by methionine, lysine, threonine and, to a lesser extent, tryptophan. Other amino • Focus your sales and marketing acids are less likely to penetrate this market due to high pricing and/or ready efforts on high growth areas. availability in livestock diets. Healthy gains by the four existing additives will be attributable to agronomic advantages to farmers seeking to reduce input costs, as well as by legislative mandates in industrialized countries calling for reductions in • Propose new areas for development livestock nitrogen excretion.

The world animal feed additives market for amino acids is closely tied to global livestock inventories, primarily those of swine and poultry. Although pork consumption is expected to remain stagnant or increase slightly, poultry demand -- broilers, adult chickens and turkeys -- is projected to post strong gains in the coming years, as health consciousness permeates additional world markets and prompts a reduction in the consumption of red meat. This trend should be particularly beneficial to methionine and lysine demand, as these two amino acids are the first and second limiting amino acids, respectively, for poultry.

Amino acid-based feed consumption is expected to experience its strongest growth in Western economies where technologically oriented farms have flourished (e.g., the US);World in many Methioninecases, such farms Demand are run by large, corporate enterprises. Nevertheless, adoption of amino acid feed additives will not be limited to North Item America and Western Europe;1989 Argentina, 1994 for example, 1999 is characterized 2004 2009 by family- owned farms, but has a tradition of embracing novel technologies and is expected Livestock Inventories*to be (mil among head) the significant12084 consumers 14738 of methionine, 15832 lysine 19200 and threonine. 23300 $ methionine/000 head 69.3 75.2 89.4 93.6 98.6 SAMPLE TABLE Methionine Demand (mil $) 838 1108 1415 1797 2298

$/lb 1.47 1.44 1.43 1.39 1.38 Methionine Demand (mil lbs) 571 769 989 1289 1669

% methionine 22.2 25.9 24.9 24.1 23.6 Amino Acids Demand (mil $) 3775 4280 5680 7455 9735

*poultry and swine

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World Amino Acids #1264 Order form on last page 7 Supply & Demand by Country & Region

The Countries Sections analyze supply and demand trends and consider the EUROPE threats and opportunities in each France - Suppliers country and region.

EUROLYSINE is the leading lysine supplier to the French market. The company is a wholly ownedSAMPLE subsidiary of AjinomotoPAGE and has an annual lysine capacity of approximately 120 million pounds at its plant in Amines, France.

Degussa, one of the major methionine suppliers to the French market, manufac- tures methionine at its plant in Ham, France; the company’s Fine Chemicals group offers such specialtyASIA/PACIFIC amino acids as L-proline, L-serine, DL-valine and D- phenylalanine through its Rexim (France) subsidiary. In November 1999, Degussa-Huels announced plans to expand Rexim’s Ham facility; this $22 million Indonesia - Products project will raise Rexim’s capacity for specialty amino acids as well as synthesis. Aventis also supplies methionine to the French market; it is the only is by far the major amino acid product sold in the manufacturer to offer both liquid (RHODIMET AT88) and dry (RHODIMET Indonesian market, with combined capacities exceeding 500 million pounds; NP99) formulations of methionine to the global livestock market. Aventis is back- however, Indonesian MSG exports have been rising at a significantly faster rate integrated to acrolein, a critical intermediate in methionine production. than domestic consumption, indicative of the fact that the Indonesian MSG market is relatively mature vis-a-vis markets in other parts of the Asia/Pacific region, OtherLatin fine chemical America: companies Amino participate Acids in theDemand French market by Type as well, supplying many of which import MSG in quantity from Indonesia (e.g., Taiwan, Cambodia, the pharmaceutical and cosmetic (million markets. dollars) Isochem, for example, SNPE’s Singapore). pharmaceuticals and active ingredients subsidiary, inaugurated a cGMP (good manufacturing practices) plant at Toulouse, France, for multistage production, The Indonesian MSG industryItem has continued to make advances, despite the 1989 1994 1999 2004 2009 primarily of amino acids in April 2000. setbacks associated with the Asian financial crisis of the late 1990s. Indonesia’s principal advantage in MSG has been the country’s ready access to molasses, the major raw material used in Latinthe America ofPopulation MSG. Molasses (mil) is typically 348.8 381.0 410.7 438.4 466.6 obtained as a byproduct of sugar $ amino production; acids/capita however, since most Indonesian 0.7 0.8 1.0 1.4 1.9 MSG producers are not integrated into sugar, molasses supplies can periodically Amino Acids Demand 261 296 426 620 892 tighten, as the sugar industry can often get a better price by exporting its molasses Methionine 97 114 158 195 240 rather than supplying it to MSG Phenylalanine manufacturers. In some cases, rather than starting 47 58 74 99 140 from molasses, producers import Lysine unrefined glutamic acid and convert it to MSG. 45 36 73 132 217 In addition, a number of so-called Glutamic “repacking” Acid companies -- mainly in Central 43 42SAMPLE 41 TABLE 54 70 Java -- do not actually produce Other MSG; rather, they buy MSG in bulk and resell it 29in 46 80 140 225 smaller packages. $/lb 1.78 1.53 1.64 1.75 1.85 Lysine is expected to offer outstanding opportunities in Indonesia over the next Amino Acids Demand (mil lbs) 147 193 260 355 481

% Latin America 75.0 75.5 76.1 76.7 77.2 Other World Amino Acids Demand 348 392 560 808 1156

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World Amino Acids #1264 Freedonia Industry Study 8 Industry Structure Sample page from Freedonia Industry Study

Gain#1111 a better World global Security understanding Products of & Sys- yourtems competition and analyze your company's position in the industry with information about: INDUSTRY STRUCTURE • market share Research & Development • licensing and related agreements Research and development is a vital ingredient in the long term health and survival of most businesses and particularly necessary in the amino acids industry, where • manufacturing requirements new, value-added uses are constantly being sought. In addition, investment in research can -- and companies hope, will -- lead to the development of proprietary • competitive strategies technology. For amino acid producers, most of this novel technology has come in the area of fermentation. For example, in its US facilities, Kyowa Hakko Kogyo has made technical improvements to the fermentation of amino acids from corn. • research and development SAMPLE PAGE -- especially genomics -- is likely to have the most significant long- • marketing and distribution term impact on the development of fermentation products in general and amino acids in particular. In 1999, Kyowa Hakko Kogyo deciphered the genome of the amino acid-producing bacterium C. glutamicum; in collaboration with Degussa, • mergers and acquisitions LION Bioscience (Heidelberg, Germany) also embarked on an effort to sequence C. glutamicum. Both companies believe that by determining the full DNA sequence of an organism involved in bulk chemical production, they will be able to isolate genes leading to fermentation processes with higher yields, and to the discovery of novel metabolic pathways that will permit commercial production of other amino acids. To date, genes involved in the synthesis of methionine, lysine and threonine have all been extensively characterized.

Manufacturing Requirements

Reflecting the limited pricing flexibility of most compounds, producers of amino acids have pursued cost-saving strategies based on technological advances in manufacturing processes. Beyond cost considerations, stricter GMP (good manufacturing practices) regulations on compounds sold to food, pharmaceutical and dietary supplement markets will force raw material suppliers to provide end

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World Amino Acids #1264 Order form on last page 9 Company Profiles

The Profiles Section analyzes 24 companies active in the world amino acid industry. These profiles represent a sampling or cross-section of the

types of companies involved in the COMPANY PROFILES industry. Kyowa Hakko Kogyo Company Limited 1-6-1, Ohtemachi Divisions, subsidiaries, joint Chiyoda-ku, Tokyo 100 ventures, etc., are discussed under Japan 813-3282-0007 appropriate parent companies.

BioKyowa Incorporated Sources for profiles included: 5469 Nash Road Cape Girardeau, MO 63702 573-335-4849 • Information provided by key staff members in the Kyowa Hakko Kogyo operates in four business segments: Pharmaceuticals and respective companies Bio-Products; Liquor and Food; Chemicals; and Others. Manufacturing, clinical drug testing, research and development, and marketing is conducted in Asia, the US and Europe. Kyowa Hakko Kogyo’s sales in FY 1999 totaled $3.2 billion • Annual reports ($2.8 billion derived from Japan, $165 million derived from North and Latin America, $116 million derived from Europe, $135 million derived from Asia and • 10-K reports $7 million derived from the rest of the world). The Company employed 5,045 in FY 1999.

• Security analysts reports Kyowa Hakko Kogyo generated approximately $335SAMPLE million in global PAGE amino acids revenues in 1999, making it the fifth leading firm in the market, with a 5.9 percent share. Like rival , Kyowa Hakko Kogyo has pursued a • Corporate product literature diversification strategy, which has allowed it to establish strong positions in lysine, monosodium glutamate and a variety of other amino acids primarily for sale to the food, feed and pharmaceutical markets.

The Company produces amino acids, among other products, through its $1.6 billion Pharmaceuticals and Bio-Products segment and its $935 million Liquor and

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World Amino Acids #1264 Freedonia Industry Study 10 Companies Profiled Aceto Corporation Ajinomoto Company Incorporated Euro- SA EUROLYSINE SA Heartland Lysine Incorporated Archer-Daniels-Midland Company Asahi Company Limited Aventis SA Rhone-Poulenc Animal Nutrition TCP Behai BASF AG Baxter International Incorporated Clintec Nutrition Cargill Incorporated Midwest Lysine LLC Cheil Jedang Corporation PT Cheil Samsung Indonesia Daesang Corporation DSM NV Holland Sweetener Company Goodrich (BF) Company Great Lakes Chemical Corporation NSC Technologies LLC Japan Tobacco Incorporated Thai Foods International Kyowa Hakko Kogyo Company Limited Agroferm BioKyowa Incorporated Fermentaciones Mexicanas Shanghai Guan Sheng Yuan Kyowa Novus International Incorporated Pharmacia Corporation Euro-Aspartame SA Company Pharmline Incorporated Sumitomo Chemical Company Limited Takeda Chemical Industries Limited Tanabe Seiyaku Company Limited Tate & Lyle plc Amylum Europe NV Orsan SA VEBA AG Degussa-Huels AG Fermas sro Midwest Lysine LLC Rexim

World Amino Acids #1264 Order form on last page 11 Forecasting Methodology

Freedonia does not just collect and reprint data; Freedonia develops data. Our analysts thoroughly investigate an industry by extensively interviewing key industry participants and analyzing information from sources such as associations, govern- ment and trade literature. Once this The Freedonia research is complete, Freedonia establishes Economics Group Freedonia one set of forecasts. All writing, editing In-house Research Consistent framework and forecasting is done in-house to assure of indicators on . . . • Quantitative forecasting quality and consistency. In cases where • Food & Beverage Shipments • Industry structure & market • Gross Domestic Product share analyses data does not exist, Freedonia develops the • World Population • Product analyses & forecasts data based on input/output ratios, bills of . . . and many others materials and flow charts. The following chart summarizes Freedonia's methodology.

Methodology for World Amino Acids

Proprietary Extensive Interviews Electronic Database • Key participants • Trade publications • Industry experts • Government reports • End-users • Corporate literature • Online databases . . . and many others

World Amino Acids #1264 Freedonia Industry Study 12 The Freedonia Group, Inc. is a leading international industry study/ About database company. The Freedonia Group Since 1985, Freedonia has published over 1,500 titles covering areas such as plastics, chemicals, coatings and adhesives, building materials, industrial components and equipment, health care, packaging, household goods, security, and many other industries.

Freedonia has produced a wide variety of titles, including:

• World Nutraceuticals • Food & Beverage Additives • Pharmaceutical Chemicals • Industrial Starch & Other Corn Chemicals

Because Freedonia is a reliable information source, our forecasts are cited in numerous publications such as The Wall Street Journal, The Financial Times, Chemical Week and Chemical Market Reporter.

Advantages In-house operations of Freedonia Reports Because all of our staff work at the same location, interaction between analysts and departments provides a strong system of checks and balances.

Consistency Our Economics Group develops indicators that are used by all analysts. Therefore, every Freedonia study is based on a consistent set of economic assumptions (GDP, world population, food and beverage shipments, etc.).

Reliable forecasts Because all of our forecasts consider the environment in which a product or industry is operating, as well as threats and opportunities to the market, Freedonia forecasts are reliable indicators of future performance.

One-on-one interviews All studies are produced by conducting interviews with key industry participants and end-users.

Proprietary electronic database Freedonia’s analysts can tap into an extensive in-house electronic database containing corporate literature (including private company information), trade publications, government reports and many other sources of information.

World Amino Acids #1264 Order form on last page 13 About Our Customers Freedonia's clients include major US and international companies in the manufacturing, services, consulting and financial sectors.

Typical purchasers of Freedonia studies :

• Key Executives • Corporate Planners • Market Researchers • Financial Analysts • Information Centers • New Product Developers • Merger & Acquisition Specialists

Since 1985 we have provided research to customers ranging in size from global conglomerates to one person consulting firms. More than 90% of the industrial companies in the Fortune 500 use Freedonia research to help with their strategic planning.

Some of Freedonia's customers in the amino acid industry include: Anjinomoto Company Incorporated, BASF AG, Cargill Incorporated and Great Lakes Chemical Corporation.

About the Author Misha Angrist, Ph.D. Research Analyst

Misha Angrist is a research analyst at The Freedonia Group. Focusing on biotechnology, genetics, and plant derived chemicals, Angrist recently completed World Agricultural Biotechnology: GMOs and is assisting on other biotechnology and genetic related research projects.

Prior to joining The Freedonia Group, Inc., Dr. Angrist was a research associate in Human Genetics at Case Western Reserve University. He authored several key papers on the genetics of Hirschprung disease.

Dr. Angrist holds a B.A. in psychology from Indiana University, Bloomington, an M.S. in biology from the University of Cincinnati, and a Ph.D. in genetics from Case Western Reserve University.

World Amino Acids #1264 Freedonia Industry Study 14 Industrial Starch & Other Corn Chemicals Greater demand for naturally derived polymers Related Studies and fermentation products will contribute to gains for corn starch and other corn-derived From Freedonia chemicals such as sorbitol, and lysine. This study analyzes the US starch and corn chemical industry, with historical data and fore- Amino Acids casts to 2004 and 2009 by product, function US demand for amino acids will advance over 5% and market. The study also examines the mar- annually. Animal feed additives will remain the larg- ket environment, details industry structure and est market at over 60% of demand, while energy- For more information about competitive strategies, presents market share boosting dietary supplements will grow the fastest. Anti-aging cosmeceuticals based on cysteine and bio- these or other Freedonia titles, data and profiles leading industry participants. #1312...... 8/00...... $3,500 degradable plastics based on will emerge please contact us at: as the most promising applications. This study ana- lyzes the US amino acid industry to 2003 and 2008 by type and end-use application. It also evaluates The Freedonia Group, Inc. Pharmaceutical Chemicals market share and profiles key companies. The US market for pharmaceutical chemicals is #1121...... 5/99...... $3,500 Phone: (440) 684-9600 analyzed in this study, including bulk actives, in- active ingredients and intermediates. It provides (800) 927-5900 historical (1989, 1994, 1999) data and forecasts Fax: (440) 646-0484 (2004, 2009) for pharmaceutical chemicals by therapeutic class (e.g., central nervous system, car- diovascular, hormonal, anti-infective), regulatory Cosmetic & Toiletry Chemicals status (ethical and over-the-counter) and produc- US demand for chemicals in cosmetics and toi- tion source (merchant and captive/toll). The study letries will grow over 5% annually. Market value also details industry structure and market share, gains will be driven by a shift toward more drug- and profiles key companies. like active ingredients, and by rising demand for #1311...... 8/00...... $3,800 products that protect from sun, heat, pollution, etc. Ingredients used in products targeted at ag- ing and ethnic markets will further spur growth. World Nutraceuticals This study analyzes the $5 billion US cosmetic World demand for nutraceuticals will grow over and toiletry chemical industry to 2003 and 2008 10% per year. Functional food additives will by type, function and market. It also presents grow the fastest spurred by new products, broad- market shares and profiles key companies. ening end-use applications, greater pricing flex- #1109...... 5/99...... $3,400 ibility and increasing number of health conscious consumers. Global demand for herbal extracts will also advance at a strong pace. This study analyzes the $6.8 billion world nutraceutical in- dustry by product group in six geographic re- gions and 12 individual countries. It also details Nutraceuticals market share and profiles key producers. Nutraceutical demand in the US will grow nearly #1289...... 6/00...... $4,600 10% annually. High value-added nutraceuticals (e.g., natural vitamin E, soy isoflavones, stan- dardized herbal extracts, new functional addi- tives) will grow the fastest, driven by new FDA Nutraceuticals - regulations that will reclassify nutraceuticals as Private Companies Report over-the-counter drugs requiring higher quality Several hundred private firms compete in the ingredients. This study analyzes the $1.7 billion US nutraceuticals market. Seven of these each US nutraceutical industry to 2003 and 2008 by generate over $50 million in annual nutraceutical type and end-use. It also evaluates market share sales, with others holding strong niche positions. and profiles key industry participants. This report profiles over 130 privately-held pro- #1099...... 3/99...... $3,400 ducers, formulators, end-users and distributors (e.g., Cargill, Global Health Sciences, Leiner Health Products, Melaleuca, Nutrilite, Reilly In- dustries). The report also forecasts industry de- mand, evaluates company market shares, and lists companies by product and location. #1154...... 8/99...... $3,000

World Amino Acids #1264 Order form on last page 15 How to Order

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