Campus Growth 5

Vitae:

The magazine of the University of Massachusetts Medical School

Spring / Summer 2001 Vol. 23 No. 3

campus growth 5

inside: The Three ‘I’s’ (page 10) Our Time to Lead (page 26) A Decade of Distinction (page 28) Contents:

school of medicine, opened in 1970 The University of Massachusetts Medical School graduate school of biomedical sciences, opened in 1979 graduate school of nursing, opened in 1986

school of medicine, opened in 1970 The University of Massachusetts Medical School graduate school of biomedical sciences, opened in 1979 graduate school of nursing, opened in 1986 Five Eight

building on success for the common good

Vitae: L., the plural of life

The name of this magazine encompasses the lives of those who make up the UMMS community, for which it is published. They are students, faculty, staff, alumni, volunteers, benefactors and others who aspire to help this campus achieve Ten Thirteen national distinction in education, research and public service.

driving education decades of research

2 news & notes 25 development update

15 grants & research 28 the last word

17 alumni report Contents:

school of medicine, opened in 1970 The University of Massachusetts Medical School graduate school of biomedical sciences, opened in 1979 graduate school of nursing, opened in 1986

school of medicine, opened in 1970 The University of Massachusetts Medical School graduate school of biomedical sciences, opened in 1979 graduate school of nursing, opened in 1986 Five Eight

building on success for the common good

Vitae: L., the plural of life

driving education decades of research

2 news & notes 25 development update

15 grants & research 28 the last word

17 alumni report News & N tes:

o David Drachman, MD Jay Himmelstein, MD, MPH

umms professor a ‘ticket to work’ explores drug’s for people with effect on dementia disabilities U.S.News & World Report, in its With results certain to impact future Attainment of competitive “Best Graduate Schools” issue research on the treatment of cognitive umms researchers employment continues to be a contribute to published in March, ranked the impairment and dementia-inducing significant obstacle for people with pivotal issue of University of Massachusetts diseases such as Alzheimer’s, a new disabilities. However, with guidance nature Medical School fourth in the nation study co-authored by Professor and from UMMS, the Massachusetts On February 15, 2001, the Chair of the Department of Neurology, Division of Medical Assistance (DMA) on its list of Top Medical Schools– prestigious journal Nature unveiled David Drachman, MD, concludes was recently awarded a $4.3 million Primary Care. UMass Medical School the first draft sequence of the that people age 50 and older could grant to develop and evaluate programs praised its exceptional faculty in human genome. The result of a be 70 percent less likely to develop to help individuals with disabilities the advertisement above, for collaboration involving 20 groups dementia if prescribed cholesterol- meet their employment goals. providing quality instruction to its from the United States, the United nih awards $ 6.7 million lowering drugs called statins. medical students—recognized by Kingdom, Japan, France, Germany Because of successful collaboration for cancer research a U.S.News “Top Ten” ranking Because vascular and cholesterol- and China, the draft sequence was between UMMS and DMA on various related mechanisms are thought generated from a physical map and public policy issues, when a Medicaid every year since 1995—and leading The rewards of a collaborative research environment were clearly evident in to have a role in the development covers approximately 94 percent of Infrastructure Grant was made America’s medical schools in March, when the University of Massachusetts Medical School was awarded a of Alzheimer’s disease and vascular the human genome. available through the federal Ticket innovative curriculum and dementia, Dr. Drachman and to Work and Work Improvement educational research. five-year, $6.7 million program grant from the National Institutes of Health Director of the UMMS Program in co-authors, including Dr. Hershel Incentives Act, DMA turned to the (NIH). Granted to the UMass Cancer Center, the funds will support the Gene Function and Expression Jick of the Boston University School Medical School to help the agency efforts of a team of 50 UMMS faculty and staff representing a variety of basic Michael R. Green, MD, PhD, first central mass. of Medicine, undertook an vie for, and ultimately, receive the and clinical departments. Immense in its scope, the project will investigate Howard Hughes Medical Institute heart transplant epidemiological study of the potential funds. According to Principal performed the method by which genes are redistributed in the nucleus of a tumor cell. Investigator and professor of effects of statins on dementia. Investigator Jay Himmelstein, The cooperative effort comprises a group of junior and senior investigators with molecular medicine, was one of the Launching a new era in cardiovascular Concluding that patients prescribed MD, MPH, UMMS assistant laboratories in every research facility on the Worcester campus and will incorporate experts to contribute to the notable medicine in Central Massachusetts, statin drugs were 70 percent less chancellor for health policy and molecular, cellular and genetic approaches to this scientific dilemma. issue with the article, “Expressing UMMS surgeons performed the likely to have dementia than those director of the Center for Health According to Principal Investigator Gary S. Stein, PhD, the Gerald the Human Genome.” With UMMS first cardiac transplant surgery in with no diagnosis of high cholesterol Policy and Research, the grant will L. Haidak, MD, and Zelda S. Haidak Professor of Cell Biology, and deputy co-authors Rosella Tupler and the state outside Boston on February or exposure to cholesterol-lowering address systematic inequities that director of research for the Cancer Center, the grant was a direct consequence Giovanni Perini, Dr. Green 27, followed in quick succession by drugs, Drachman, Jick, et al, continue to affect the disabled of the successful collaboration among several UMMS departments over the examines the implications of the procedures in April and May. The encouraged other researchers to population and “fund lasting past five to seven years. “This grant reflects something very positive about the human genome for gene expression cardiac transplantation program’s conduct further studies to enhancements to the Medicaid Medical School. This is a group of people who can work effectively together, processes. The authors write, “The team, directed by James S. confirm their findings. According program to improve health systems and more importantly, truly enjoy doing so,” Dr. Stein said. availability of the human and other Gammie, MD, UMMS assistant to the authors, “If substantiated, and employment opportunities.” genome sequences will revolutionize professor of surgery, and Lana the implications of this study are all fields of biomedical research. But, DMA Director of Plans for the Elderly Tsao, MD, UMMS assistant considerable. These findings suggest Shown in the future home of the UMass Cancer Center, grant researchers from left to right, as the genome is itself the object and Disabled and Project Co-director professor of medicine, performed that the use of statins could front row: G. Wayne Zhou, PhD; Janet Stein, PhD; Gary Stein, PhD; Jane Lian, PhD. of gene expression, the impact may Eleanor Shea-Delaney agreed. “Our the surgeries at clinical partner substantially reduce the risk of dementia Back row: Andre J. Van Wijnen, PhD; Anthony Imbalzano, PhD; Greenfield Sluder, PhD; be particularly profound for those partnership will greatly improve the UMass Memorial Health Care. in the elderly, either by delaying Stephen Doxsey, PhD; German Pihan, MD; and Jeffrey A. Nickerson, PhD of us studying this process.” quality of services available for both its onset, or by opposing specific working adults with disabilities and or general age-related changes that those who wish to work.” result in cognitive impairment.”

2 Vitae spring - summer 2001 spring - summer 2001 Vitae 3 News & N tes:

o David Drachman, MD Jay Himmelstein, MD, MPH

2 Vitae spring - summer 2001 spring - summer 2001 Vitae 3 If a picture paints a thousand words, how descriptive are three dimensions? At theUniversity of Massachusetts Medical School, buildings and spaces outline the story of a decade of expansion.

Bernard LaFayette Jr., EdD Paul Appelbaum, MD Andre Biuckians ’01

by mary beth dziewietin

umms community psychiatry chair student elected challenged to elected to iom vice speaker of Building on activism ama section Paul S. Appelbaum, MD, With unparalleled eloquence and the Arnold F. Zeleznik Professor of UMMS fourth-year medical inflections of humor that reinforced Psychiatry, chair of the Department student Andre Biuckians has the seriousness of his topic, Bernard of Psychiatry and director of the Law been elected vice speaker of the LaFayette Jr., EdD, spoke of and Psychiatry Program at UMMS, American Medical Association Succ ss the history and progress of the Civil has been elected to membership in Medical Student Section (AMA-MSS) Rights Movement as the keynote the National Academy of Sciences’ by fellow student members. The speaker at UMMS’ 13th Annual AMA-MSS is the largest medical e Institute of Medicine. Each year, Tribute to the Rev. Dr. Martin Luther current active members of the student organization in the country, King Jr. in January. Distinguished Institute elect new members from with over 47,000 members, and scholar-in-residence and director among candidates chosen for their is dedicated to representing the As every prospective student knows, words and student population, responded by of the Center for Nonviolence and major contributions to health and interests of medical students and filling two courtyards adjacent to Peace Studies at the University of medicine, or to related fields such as improving the quality of medical photos in a catalog can’t compare to a visit for the library in the school building Rhode Island, LaFayette described social sciences, law, administration education. In his capacity as vice conveying the sense of a place. But visitors to with small-scale, high-tech the irony of a nation that expounded and economics. speaker, Biuckians will work with case study rooms and group study the virtues of freedom while supporting the speaker to determine the the University of Massachusetts Medical School Recognized as one of the country’s areas. The Allan S. Goff Learning segregation. “The struggle wasn’t organization’s agenda and leading forensic psychiatrists, should be prepared: a tour might take awhile. Center opened in June 1997. about segregated buses. We were coordinate all activities for the Appelbaum has published and dealing with the fact that this nation, interim and annual meetings. “We designed portions of the Learning Center to address spoken extensively on critical mental that claimed to be a democracy, would The campus map in the 1991-1993 Medical School the requirements of each of the three schools,” recalled health and legal issues ranging from “We are very fortunate to count allow this situation to exist,” he said. Catalog pictures five buildings and a parking garage on the Director of Facilities Management Timothy M. Fitzpatrick, obtaining informed consent in Andre among our students,” said institution’s 67 acres, and one building in the Massachusetts whose 25 years at UMMS make him a knowledgeable tour While recognizing that progress has treatment and research, to protecting Aaron Lazare, MD, chancellor Biotechnology Research Park across Plantation Street. guide. “I think we were fairly successful—successful been made, LaFayette implored his patients’ confidentiality, to the and dean. “His commitment to (Anderson House, a bit farther north on Plantation, is off enough that the rooms are always booked,” he added. audience to be wary of apathy. “You public health advocacy emulates the diagnosis, prevention and treatment the page.) In the current edition, catalog viewers find not can’t stand by and watch,” he stressed. core mission of the Medical School.” The need for space, of course, is basic to the institution’s of violent behavior. His achievements only half a dozen new structures around the main campus “We came over here on different growth. For several reasons, research space in particular as a forensic psychiatrist, spanning but also four more campuses. ships, but right now, we’re in the clinical evaluation and scholarly has been of great importance: achievements in research “Old” at UMMS is relative: its first structure was the Shaw same boat. The world is coming research, complement the Institute’s help fulfill the Medical School’s mission and benefit Building, which dates back only to 1970, and most of the to you, with folks of different colors, mission to advance and disseminate humanity as a whole; a nationally recognized research other facilities on the campus in 1991 were completed by different languages and different scientific knowledge to improve program contributes to the viability of the entire educational 1976. The tour of the institution’s recent expansion begins cultures. We have to teach our human health. “I am honored by institution; and a critical mass of investigators and resources at a new space in an old place. children that they are part of that my election to the Institute,” said is essential to attracting ever more competitive external evolving world.” Appelbaum. “I look forward to During the 1990s, as a result of changes in medical education funding. UMMS was not alone in recognizing the changing working with some of the finest nationally and at UMMS, new methods of teaching and demands of scientific research, and unions with other minds in medicine on the major learning created the need for different kinds of classrooms. institutions as well as new construction added to the health policy problems that face The Medical School, already crowded by a growing Medical School’s facilities. the nation today.”

Above: Timothy M. Fitzpatrick | Background: A classroom in the Goff Learning Center

4 Vitae spring - summer 2001 spring - summer 2001 Vitae 5 If a picture paints a thousand words, how descriptive are three dimensions? At theUniversity of Massachusetts Medical School, buildings and spaces outline the story of a decade of expansion.

Bernard LaFayette Jr., EdD Paul Appelbaum, MD Andre Biuckians ’01

by mary beth dziewietin

Above: Timothy M. Fitzpatrick | Background: A classroom in the Goff Learning Center

4 Vitae spring - summer 2001 spring - summer 2001 Vitae 5 Spring at the Worcester Campus | Rose and Gordon Research Laboratory, Worcester Foundation Campus | Benedict Building, Worcester Campus State Laboratory Building, Jamaica Plain Campus | Brudnick Neuropsychiatric Research Institute | Lab ventilation atop Biotech Four

In 1991, all wet-lab research was conducted in the School The state laboratory complex and the Shriver Center are construction of the 32,000-square-foot facility. With names and spaces

and leased space in Two Biotech at the Massachusetts part of Commonwealth Medicine, a UMMS initiative that additional funds from the Department of Mental Health, The year 1992 saw two milestone achievements at the former Biotechnology Research Park (MBRP). UMMS purchased lends expertise and support to 10 state agencies. Fitzpatrick the building serves as evidence of UMMS efforts over the University of Massachusetts Medical Center: the opening of the Two Biotech the following year, and increased its presence described Commonwealth Medicine as one of Facility past decade to seek new sources of support. Joseph T. Benedict Building, the institution’s first new structure on the other side of Plantation Street with the acquisition Management’s “biggest clients;”as well as the Jamaica Plain The last stop is the eye-catching structure that likely drew other than the parking garage since 1976 and the culmination of One Biotech and lease of Four Biotech in 1998; the spaces and Waltham sites, the group occupies space at the Foundation many tour participants: a 10-story, glass-covered, 360,000- of a major collaboration with the commonwealth and city to accommodate, among others, the Program in Molecular Campus, MBRP and Auburn Campus, south of Worcester. square-foot research laboratory building. According to rehabilitate Worcester City Hospital. Six years later, the merger Medicine, Commercial Ventures & Intellectual Property, Fitzpatrick, construction is substantially complete on of the UMass clinical system and Memorial Health Care, another and UMMS scientists of the former Worcester Foundation “we’re going to use this project levels 1 through 4, and though the building won’t be landmark event, transferred ownership of the sites to UMass for Biomedical Research (WFBR), one of three institutions entirely finished, researchers and staff will begin moving Memorial Health Care. to combine with UMMS in the last few years. as a model to say that yes, you can do in during the first week of September as scheduled. “For The clinical partnership has created and expanded opportunities An independent research facility with an international a project of this size, carried out this quickly—30 months for the advancement of the Medical School’s mission. As well as reputation, the WFBR merged with the Medical School in good construction openly, honestly, from pre-conceptual design to occupancy—I’d say it’s supporting education and service programs at its hospital and 1997. The Foundation’s 80-acre campus in Shrewsbury is unusual that we’ve been able to stay on target,” said ambulatory care sites, UMass Memorial pledged $30 million the first UMMS-owned space on the tour not in walking cost effectively—and on time.” Fitzpatrick. “It’s one thing to do it fast, but to do it right toward the cost of the new UMMS research laboratory building distance of the main campus. (The hill to the MBRP is and do it fast is a challenge.” to fund cutting-edge research. steep, but not insurmountable.) Of the nine major buildings The facilitating factor was the success of the UMMS The construction of the Benedict Building and the renovation on the Worcester Foundation Campus, three—the The drive from Auburn to Worcester is long enough to leadership team, led by Chancellor and Dean Aaron Lazare, of the Family Health Center (the old City Campus) addressed the Hoagland-Pincus Conference Center, Chang Building, calculate that, of the more than 400,000 square feet of wet- in finding ways to work with the commonwealth that allow shortage of convenient, comfortable patient-care space brought about by a growing number of patients seeking a greater array and Rose and Gordon Research Laboratory—have since lab research space purchased, leased or acquired through the Medical School to build more efficiently. Said Fitzpatrick: of services. Both the need and the cause remain, and UMass undergone major renovations. mergers, only 80,000 was available for new investigators. “We’re going to use this project as a model to say that yes, Back on Plantation Street, the tour approaches the Medical Memorial has several projects underway in response: the system Two more unions created UMMS campuses even you can do good construction openly, honestly, cost School’s newest structures. recently completed a technologically advanced ambulatory surgical farther east of Worcester. Also in 1997, the commonwealth effectively—and on time.” center at the Hahnemann Campus, and is expanding the cardiac transferred operation of the Massachusetts Biologic Adjacent to the MBRP, on the grounds of Worcester State With projects in process such as another parking garage— catheterization labs at the University Campus and the Ambulatory Laboratories and the New England Newborn Screening Hospital, the Irving S. and Betty Brudnick Neuropsychiatric part of the UMass Memorial Emergency Department Cancer Center at the Memorial Campus. Three UMass Memorial Program in Jamaica Plain from the Department of Public Research Institute opened in 2000. The facility is devoted expansion plans—and a $65 million vaccine filling and member hospitals—Clinton, HealthAlliance and Marlborough—also Health to the Medical School. The Eunice Kennedy Shriver to biological research into the causes, diagnoses and manufacturing facility at the Jamaica Plain Campus, are making capital improvements to enhance access to health care. Center in Waltham merged with UMMS last year. treatment of chronic and serious mental disorders and is tourists in the next decade better plan on wearing Researchers at both facilities continue to pursue their the result of the vision of Irving and Betty Brudnick of comfortable shoes. established investigations. Weston. The Brudnicks contributed $2.5 million toward

Background: The Research Laboratory Building

6 Vitae spring - summer 2001 spring - summer 2001 Vitae 7 Spring at the Worcester Campus | Rose and Gordon Research Laboratory, Worcester Foundation Campus | Benedict Building, Worcester Campus State Laboratory Building, Jamaica Plain Campus | Brudnick Neuropsychiatric Research Institute | Lab ventilation atop Biotech Four

In 1991, all wet-lab research was conducted in the School The state laboratory complex and the Shriver Center are construction of the 32,000-square-foot facility. With names and spaces

Background: The Research Laboratory Building

6 Vitae spring - summer 2001 spring - summer 2001 Vitae 7 The concept of Commonwealth colleagues at the Division of Medical help defray school costs in 325 Medicine is tied to the goal to create Assistance (DMA), the Commonwealth municipalities or districts for health- a relationship with the state to deliver Citation for Outstanding Performance related services, benefiting localities psychiatric care of the highest this past fall. With the award, the from Boston to the Berkshires. quality to patients in the public RMG’s John Robertson, John Seaver, Working with the DMA and the sector. In 1982, Dr. Lazare became Bella Tong, Teresa Pastore, Donna Department of Education (DOE), professor and chair of the Department Manoogian, Kimberli Keith, Marc the RMG developed reimbursement of Psychiatry, and immediately set to Thibodeau and Alan Levites realized methodologies; trained school staff that goal. For his accomplishments their dedication to CM’s mission of in claims preparation; helped to in this area, the chancellor received facilitating initiatives that benefit all amend state and federal regulatory the University’s Distinguished residents of Massachusetts. Said language; and crafted a vehicle for Professional Public Service Award in CM’s Manning: “Receipt of this transferring funds from the federal by andrea l. badrigian 1988 “for exceptional achievement in award is a prime example of two government to the localities. Staff serving the interests of the people” of agencies within the family of state members continue to administer the Massachusetts. The Department of agencies initiating an extraordinary program for the DMA, providing Psychiatry won four subsequent effort on behalf of the commonwealth.” management and technical support awards for its public sector activities. The RMG has a history of developing to the municipal providers and to Manning came to UMass Medical innovative funding mechanisms the Medicaid agency. Center in 1978 to serve as administrator resulting in the garnering of over “The team exhibited exemplary for the psychiatry department. In $500 million in non-tax revenue for leadership in making all of the For the that role throughout the 1980s, he the commonwealth. These programs appropriate changes to state processes coordinated the department’s fiscal involve the recovery of federal funds in order for the municipalities to Common G od Commonwealth Medicine partners with state agencies to benefit Massachusetts’ citizens—with rewarding results. and management activities and was to offset state expenditures in receive the federal windfall,” noted active in the formulation of policy various agencies. The RMG was Manning. “Members of the team o for its public sector work. In 1993, presented the citation this fall for took on the formidable challenge A meeting of two minds in the UMMS Department of Psychiatry in the early 1980s has led to he was presented the Department initiating yet another nationally of coordinating this involvement, of Mental Health’s prestigious recognized model for successfully ideas so innovative that their implementation serves as a model for the rest of the country and satisfying the program goals of the Commissioner’s Special identifying and recovering federal DMA, the DOE, the Office of the garners recognition at the highest level here in the Bay State. Commendation for his efforts in revenue, this time supporting local State Comptroller and the Legislature, supporting the rights of the mentally municipalities in providing health- whose participation was vital to the ill and for advocating for opportunities related, school-based funding for process.” The team convinced the Commonwealth Medicine (CM), initiated by Chancellor Aaron Lazare and Vice Chancellor Thomas D. Manning, is for them in the community. Five special education and the general municipalities and schools that the the state’s partner in public sector health care programs that serve to optimize efficiency, increase the value and quality years later, Manning received the student population. value of the revenue would offset the of health care expenditures, and improve access and delivery of care to at-risk and uninsured citizens. With its various Manuel Carballo Governor’s Award Dubbed “Municipal Medicaid,” costs of yet another state and federal academic, research, management and clinical components—serving the Massachusetts departments of Mental Health, for Excellence in Public Service, the the project has created a means oversight agency. Said Manning: Social Services, Public Safety and Public Health and the state’s Medicaid program—and staffed by forward-thinking commonwealth's highest honor in of delivering federal dollars to “The Massachusetts model of professionals, CM is UMass Medical School’s answer to state agencies’ quest for streamlined performance and positive returns. the field of health and human services. municipalities and local and regional recovering federal reimbursement Such an award-winning legacy has school districts by using tax revenues for schools was so well conceived been assumed by members of the to provide the state match for and implemented that many other Revenue Maximization Group (RMG) Medicaid services in schools. states have chosen to copy the of Commonwealth Medicine’s Certifying the local match, the DMA process in part or in whole. Center for Health Care Financing, draws federal matching funds for Additionally, the team participated in who received, along with their the Medicaid-covered services a national committee that played a vital delivered through the schools. role in molding policy in this area.” The program has recouped over $250 million in federal dollars to

8 Vitae spring - summer 2001 spring - summer 2001 Vitae 9 The concept of Commonwealth colleagues at the Division of Medical help defray school costs in 325 Medicine is tied to the goal to create Assistance (DMA), the Commonwealth municipalities or districts for health- a relationship with the state to deliver Citation for Outstanding Performance related services, benefiting localities psychiatric care of the highest this past fall. With the award, the from Boston to the Berkshires. quality to patients in the public RMG’s John Robertson, John Seaver, Working with the DMA and the sector. In 1982, Dr. Lazare became Bella Tong, Teresa Pastore, Donna Department of Education (DOE), professor and chair of the Department Manoogian, Kimberli Keith, Marc the RMG developed reimbursement of Psychiatry, and immediately set to Thibodeau and Alan Levites realized methodologies; trained school staff that goal. For his accomplishments their dedication to CM’s mission of in claims preparation; helped to in this area, the chancellor received facilitating initiatives that benefit all amend state and federal regulatory the University’s Distinguished residents of Massachusetts. Said language; and crafted a vehicle for Professional Public Service Award in CM’s Manning: “Receipt of this transferring funds from the federal by andrea l. badrigian 1988 “for exceptional achievement in award is a prime example of two government to the localities. Staff serving the interests of the people” of agencies within the family of state members continue to administer the Massachusetts. The Department of agencies initiating an extraordinary program for the DMA, providing Psychiatry won four subsequent effort on behalf of the commonwealth.” management and technical support awards for its public sector activities. The RMG has a history of developing to the municipal providers and to Manning came to UMass Medical innovative funding mechanisms the Medicaid agency. Center in 1978 to serve as administrator resulting in the garnering of over “The team exhibited exemplary for the psychiatry department. In $500 million in non-tax revenue for leadership in making all of the For the that role throughout the 1980s, he the commonwealth. These programs appropriate changes to state processes coordinated the department’s fiscal involve the recovery of federal funds in order for the municipalities to Common G od Commonwealth Medicine partners with state agencies to benefit Massachusetts’ citizens—with rewarding results. and management activities and was to offset state expenditures in receive the federal windfall,” noted active in the formulation of policy various agencies. The RMG was Manning. “Members of the team o for its public sector work. In 1993, presented the citation this fall for took on the formidable challenge A meeting of two minds in the UMMS Department of Psychiatry in the early 1980s has led to he was presented the Department initiating yet another nationally of coordinating this involvement, of Mental Health’s prestigious recognized model for successfully ideas so innovative that their implementation serves as a model for the rest of the country and satisfying the program goals of the Commissioner’s Special identifying and recovering federal DMA, the DOE, the Office of the garners recognition at the highest level here in the Bay State. Commendation for his efforts in revenue, this time supporting local State Comptroller and the Legislature, supporting the rights of the mentally municipalities in providing health- whose participation was vital to the ill and for advocating for opportunities related, school-based funding for process.” The team convinced the Commonwealth Medicine (CM), initiated by Chancellor Aaron Lazare and Vice Chancellor Thomas D. Manning, is for them in the community. Five special education and the general municipalities and schools that the the state’s partner in public sector health care programs that serve to optimize efficiency, increase the value and quality years later, Manning received the student population. value of the revenue would offset the of health care expenditures, and improve access and delivery of care to at-risk and uninsured citizens. With its various Manuel Carballo Governor’s Award Dubbed “Municipal Medicaid,” costs of yet another state and federal academic, research, management and clinical components—serving the Massachusetts departments of Mental Health, for Excellence in Public Service, the the project has created a means oversight agency. Said Manning: Social Services, Public Safety and Public Health and the state’s Medicaid program—and staffed by forward-thinking commonwealth's highest honor in of delivering federal dollars to “The Massachusetts model of professionals, CM is UMass Medical School’s answer to state agencies’ quest for streamlined performance and positive returns. the field of health and human services. municipalities and local and regional recovering federal reimbursement Such an award-winning legacy has school districts by using tax revenues for schools was so well conceived been assumed by members of the to provide the state match for and implemented that many other Revenue Maximization Group (RMG) Medicaid services in schools. states have chosen to copy the of Commonwealth Medicine’s Certifying the local match, the DMA process in part or in whole. Center for Health Care Financing, draws federal matching funds for Additionally, the team participated in who received, along with their the Medicaid-covered services a national committee that played a vital delivered through the schools. role in molding policy in this area.” The program has recouped over $250 million in federal dollars to

8 Vitae spring - summer 2001 spring - summer 2001 Vitae 9 specialists and generalists, the are used to help assess students’ school and the community. Many progress. The fourth year wraps parts of our present curriculum are up medical students’diverse

by sandra l. gray continuing collaborations that grew undergraduate learning experience from these conversations.” with interdisciplinary electives and research opportunities in addition Developed with input from more to more required clinical clerkships. than 20 curriculum committees, Optional Enrichment Program faculty groups and student focus electives such as American Sign groups, a revamped School of Language and End-of-Life Care Education Driven by Medicine curriculum was phased in are available across all four years. from 1995 to 1996. In the first two years, multidisciplinary courses Along with curriculum reform were expanded, and other courses came recognition that, to stay focused on teaching, faculty need support and resources of their own. the Thr e ‘I’s’ Since 1996, the OME’s Division of Faculty Development has supported e the faculty teaching series and a teaching peer-review program. Innovations in Medical Education UMMS faculty continually develop educational offerings for students through creative collaboration. Grants, administered by OME’s Division of Research and Evaluation, (clockwise from top) Innovative, interdisciplinary When Dr. Lazare took the helm Trustees approved Dr. Lazare’s provide faculty members with in 1991, the health care professions proposal to retool the formerly funding for pilot projects. and integrated—this trio of Susan Gagliardi, PhD were faced with unprecedented departmentally driven Educational professor and vice chair of cell biology The Graduate School of Biomedical “I” words well describes the changes in medical knowledge, Policy Committee (EPC) into an Sciences’ (GSBS) and the Graduate patient populations, medical interdisciplinary and authoritative Thomas Miller, PhD trajectory of curriculum GSBS dean School of Nursing’s (GSN) own technology and how health services entity reporting directly to the successes with curriculum development at the School were delivered. The consensus in chancellor and dean. Mary Alexander, EdD development have always paralleled, professor and associate dean of the GSN of Medicine, Graduate School medical academic circles was that, In 1993, four formerly separate and often intersected, with those of of Biomedical Sciences and in order to stay relevant, radical administrative offices were melded the School of Medicine. GSBS Dean transformation in medical school into the Office of Medical Education Thomas B. Miller Jr., PhD, is pleased Graduate School of Nursing education leading to the MD degree (OME). Integrating curriculum that “the GSBS has prospered over the past decade. Guided was needed. This was a view that development, student affairs, considerably over the past decade,” Lazare and a critical mass of UMMS made changes to emphasize with enrollment up over 100 percent. by Chancellor and Dean admissions and graduate medical interdisciplinary approaches. faculty shared—and a challenge they education, the OME facilitates While a departmentally based core Aaron Lazare, faculty have embraced. First-year students begin to integrate curriculum has been required for all involvement from all academic basic science with its practical invested untold energy and “A major strength of our school departments in developing and GSBS students since 1985, it became clinical applications early in their an interdisciplinary effort in 1998; has been a culture that encourages implementing interdisciplinary education via the interdisciplinary creativity, not to mention faculty to become involved in courses and educational programs. faculty representing all programs Longitudinal Preceptorship Program plan and teach a core curriculum countless hours of work, into educational planning at the Dr. Gagliardi, who currently co- and two-week Community Clerkship. grassroots level,” said Susan B. that is designed to provide the most a panoply of curriculum reforms chairs the EPC, remembers the The third year is devoted to required up-to-date material for all first-year Gagliardi, PhD, professor and vice incredible excitement generated 6-12 week clinical clerkships and that keep pace with the ever- chair of cell biology, herself a major students. “Beyond imparting by the opportunity to create change. elective one-day interclerkships knowledge, going through the core changing landscape of health player in curriculum reform at “People started really talking to addressing contemporary topics UMMS. “Dr. Lazare was the catalyst; curriculum together gives each class care and biomedical science. each other—faculty from different such as substance abuse and domestic a camaraderie and cohesiveness they faculty members responded by departments and disciplines, basic violence. Objective Structured Clinical turning ideas into reality.” In April maintain throughout their careers,” scientists and clinicians, basic Exams (OSCE) administered by the noted Dr. Miller. of 1991, the University Board of scientists and social scientists, Standardized Patient Program

10 Vitae spring - summer 2001 spring - summer 2001 Vitae 11 specialists and generalists, the are used to help assess students’ school and the community. Many progress. The fourth year wraps parts of our present curriculum are up medical students’diverse

10 Vitae spring - summer 2001 spring - summer 2001 Vitae 11 out of the hospital, the GSN Babs Soller, PhD addressed the resulting shortage of After completing the core curriculum, in-hospital caregivers with advanced primary care for six consecutive GSBS students select from several training by establishing the acute years, and in 2000 entered the fields of specialization in which to care clinical nurse practitioner U.S.News ranks of the top 50 medical conduct dissertation research. Some specialty in the Master’s program. schools overall. In 1993, the National of these, such as Neuroscience and In 1994, the GSN again responded Research Council, an agency of the Biomedical Engineering & Medical to a shortage, this time of doctorally National Academy of Sciences, Physics, are themselves inter- prepared nurse educators and ranked the GSBS in the top half of disciplinary. The Interdisciplinary researchers, by founding the programs offering PhD degrees in Craig Peterson, PhD Graduate Program (IGP) introduced Collaborative PhD Nursing Program biological sciences; Dean Miller of last year is a logical extension of the with UMass Amherst. the GSBS is confident the school GSBS philosophy that, after gaining Another key recognition has been would rank even higher today had fundamental core knowledge, each that state-of-the-art infrastructure the NRS not discontinued its PhD candidate should have maximum and technology are essential for ratings. In 1997, the GSN received latitude in designing their own PhD optimal teaching and learning. In its full eight-year accreditation from specialization. All GSBS faculty are the National League for Nursing invited to join the IGP. Accrediting Commission. Since 1991, the Graduate School of As new medical knowledge and From the outer reaches of space to the inner sanctum of DNA, UMMS investigators unravel a variety of life’s puzzles, all with an eye to ethics. Nursing has developed curriculum innovative changes in health care delivery in tandem with the School of advance, curriculum changes must Medicine’s responses to changes in continue apace. The School of health care delivery. Soon after being interdisciplinary Medicine makes ongoing refinements, appointed chancellor, Lazare met updates and additions through a with GSN faculty to address the need continuous process of evaluation, Three Decades of R search for greater cooperation between the integrated review and renewal by students as graduate school and the then well as faculty. The GSBS is working e Because of the prominence of the new research laboratory building, together with recent news by lynn c. borella UMMS-run clinical system. Afforded towards an interdisciplinary the necessary resources, the GSN biotechnology & bioengineering of sizable increases in National Institutes of Health funding, many at UMMS might be tempted brought nurses, physicians and 1997, construction of the Allan S. program with the University’s to associate Medical School research strictly with benchwork and journal publication. basic scientists together in the Goff Learning Center was completed. Boston, Lowell and Amherst classroom, hospital and community. Later this year, completion of the campuses. Under its new dean, research laboratory building will Doreen Harper, PhD, the GSN will Yet, since 1991, when Aaron Lazare, MD, became chancellor, the mission to expand the Medical School’s research “Our students take for granted open the doors to hundreds of aggressively pursue opportunities enterprise has always embraced the true meaning of the word research—studious inquiry and examination. Following something I think is unique to our investigators and their staffs. UMMS to grow research funding and are the reflections and accomplishments of three diverse research faculty, each celebrating 10 years with UMMS, who school: the easy interchange and continues to implement technology- community collaborations. Most can attest to the breadth and success of the research mission here. collaboration between disciplines,” based educational tools, such as the recently, Chancellor Lazare has said Mary K. Alexander, EdD, professor Research Associate Professor of Surgery Babs Soller, blood loss—by using light to penetrate through skin and interactive Web-based “StrokeSTOP” formed a committee to recruit for and associate dean of the GSN and PhD, embodied collaboration between academia and bones. A recent three-year, $750,000 grant from the National curriculum. Teleconferencing brings the newly created post of Vice a major architect of its Master’s in industry long before such partnerships were common. Space Biomedical Research Institute, designed to promote far-flung students and faculty Chancellor of Education, which will Nursing Science curriculum. “When Although hired to assist one surgeon, Dr. Soller’s position the development of such devices for use during space together and Information Systems’ address evolving educational needs nurses, physicians and scientists in the Division of Cardiothoracic Surgery has grown to flight, will help Soller and her team improve the current Division of Academic Computing for all three UMMS schools. learn together, they gain a true provide support to all members interested in developing technology and pursue an industrial partner. harnesses Internet technology to appreciation for what each one brings “We have much more to explore their own research projects. In addition to day-to-day help students access the most up-to- In reflecting on her 10 years at UMMS, Soller sees today’s to the health care system, and how in the area of education,” observed research program management, Soller maintains the date information in their fields. close collaboration with industry—as exemplified by the they can work together to enhance it.” Gagliardi. “And continued division’s cardiac patient database, a quality benchmarking UMass/Smith + Nephew Center for Research in Endoscopic Outside observers attest to advances collaboration between faculty in the In the mid-’90s, when the School tool that includes 13 years of pre-operative risk factors, Surgery—as one of the most significant changes she’s in the quality of education at UMMS three schools is an exciting step.” of Medicine’s emphasis on primary operative conditions and outcomes, providing useful witnessed and one in which she feels like a pioneer. over the past decade. The School care in the community for graduate information for research. “My corporate biomedical engineering experience didn’t of Medicine has been ranked by medical education took residents Soller’s most recent investigation involves the development provide me opportunity to discover the types of devices U.S.News and World Report in the top and testing of sensors based on Near Infrared Spectroscopy surgeons need. The creation of the Smith + Nephew 10 medical schools emphasizing (NIR), non-invasive devices that can assess blood and Center at UMass is unique, in that it pairs on-site engineers tissue chemistry—important indicators of shock or severe with surgeons, allowing insight into what tools surgeons

12 Vitae spring - summer 2001 spring - summer 2001 Vitae 13 out of the hospital, the GSN Babs Soller, PhD addressed the resulting shortage of After completing the core curriculum, in-hospital caregivers with advanced primary care for six consecutive GSBS students select from several training by establishing the acute years, and in 2000 entered the fields of specialization in which to care clinical nurse practitioner U.S.News ranks of the top 50 medical conduct dissertation research. Some specialty in the Master’s program. schools overall. In 1993, the National of these, such as Neuroscience and In 1994, the GSN again responded Research Council, an agency of the Biomedical Engineering & Medical to a shortage, this time of doctorally National Academy of Sciences, Physics, are themselves inter- prepared nurse educators and ranked the GSBS in the top half of disciplinary. The Interdisciplinary researchers, by founding the programs offering PhD degrees in Craig Peterson, PhD Graduate Program (IGP) introduced Collaborative PhD Nursing Program biological sciences; Dean Miller of last year is a logical extension of the with UMass Amherst. the GSBS is confident the school GSBS philosophy that, after gaining Another key recognition has been would rank even higher today had fundamental core knowledge, each that state-of-the-art infrastructure the NRS not discontinued its PhD candidate should have maximum and technology are essential for ratings. In 1997, the GSN received latitude in designing their own PhD optimal teaching and learning. In its full eight-year accreditation from specialization. All GSBS faculty are the National League for Nursing invited to join the IGP. Accrediting Commission. Since 1991, the Graduate School of As new medical knowledge and From the outer reaches of space to the inner sanctum of DNA, UMMS investigators unravel a variety of life’s puzzles, all with an eye to ethics. Nursing has developed curriculum innovative changes in health care delivery in tandem with the School of advance, curriculum changes must Medicine’s responses to changes in continue apace. The School of health care delivery. Soon after being interdisciplinary Medicine makes ongoing refinements, appointed chancellor, Lazare met updates and additions through a with GSN faculty to address the need continuous process of evaluation, Three Decades of R search for greater cooperation between the integrated review and renewal by students as graduate school and the then well as faculty. The GSBS is working e Because of the prominence of the new research laboratory building, together with recent news by lynn c. borella UMMS-run clinical system. Afforded towards an interdisciplinary the necessary resources, the GSN biotechnology & bioengineering of sizable increases in National Institutes of Health funding, many at UMMS might be tempted brought nurses, physicians and 1997, construction of the Allan S. program with the University’s to associate Medical School research strictly with benchwork and journal publication. basic scientists together in the Goff Learning Center was completed. Boston, Lowell and Amherst classroom, hospital and community. Later this year, completion of the campuses. Under its new dean, research laboratory building will Doreen Harper, PhD, the GSN will Yet, since 1991, when Aaron Lazare, MD, became chancellor, the mission to expand the Medical School’s research “Our students take for granted open the doors to hundreds of aggressively pursue opportunities enterprise has always embraced the true meaning of the word research—studious inquiry and examination. Following something I think is unique to our investigators and their staffs. UMMS to grow research funding and are the reflections and accomplishments of three diverse research faculty, each celebrating 10 years with UMMS, who school: the easy interchange and continues to implement technology- community collaborations. Most can attest to the breadth and success of the research mission here. collaboration between disciplines,” based educational tools, such as the recently, Chancellor Lazare has said Mary K. Alexander, EdD, professor Research Associate Professor of Surgery Babs Soller, blood loss—by using light to penetrate through skin and interactive Web-based “StrokeSTOP” formed a committee to recruit for and associate dean of the GSN and PhD, embodied collaboration between academia and bones. A recent three-year, $750,000 grant from the National curriculum. Teleconferencing brings the newly created post of Vice a major architect of its Master’s in industry long before such partnerships were common. Space Biomedical Research Institute, designed to promote far-flung students and faculty Chancellor of Education, which will Nursing Science curriculum. “When Although hired to assist one surgeon, Dr. Soller’s position the development of such devices for use during space together and Information Systems’ address evolving educational needs nurses, physicians and scientists in the Division of Cardiothoracic Surgery has grown to flight, will help Soller and her team improve the current Division of Academic Computing for all three UMMS schools. learn together, they gain a true provide support to all members interested in developing technology and pursue an industrial partner. harnesses Internet technology to appreciation for what each one brings “We have much more to explore their own research projects. In addition to day-to-day help students access the most up-to- In reflecting on her 10 years at UMMS, Soller sees today’s to the health care system, and how in the area of education,” observed research program management, Soller maintains the date information in their fields. close collaboration with industry—as exemplified by the they can work together to enhance it.” Gagliardi. “And continued division’s cardiac patient database, a quality benchmarking UMass/Smith + Nephew Center for Research in Endoscopic Outside observers attest to advances collaboration between faculty in the In the mid-’90s, when the School tool that includes 13 years of pre-operative risk factors, Surgery—as one of the most significant changes she’s in the quality of education at UMMS three schools is an exciting step.” of Medicine’s emphasis on primary operative conditions and outcomes, providing useful witnessed and one in which she feels like a pioneer. over the past decade. The School care in the community for graduate information for research. “My corporate biomedical engineering experience didn’t of Medicine has been ranked by medical education took residents Soller’s most recent investigation involves the development provide me opportunity to discover the types of devices U.S.News and World Report in the top and testing of sensors based on Near Infrared Spectroscopy surgeons need. The creation of the Smith + Nephew 10 medical schools emphasizing (NIR), non-invasive devices that can assess blood and Center at UMass is unique, in that it pairs on-site engineers tissue chemistry—important indicators of shock or severe with surgeons, allowing insight into what tools surgeons

12 Vitae spring - summer 2001 spring - summer 2001 Vitae 13 need for patient care.” In many ways, In addition to her contributions can unfold or remodel the chromatin Soller feels that her position at to the Macy Initiative in Health to allow repair of damaged DNA and UMMS was a precursor to this melding Communication, Clay is well known facilitate the reading of genetic of academic medicine and industry. for her role in the end-of-life material. Peterson’s lab has been “By conducting such investigations curricula, specifically the elective investigating DNA repair and how Gr nts & Research: at a medical school, I have clinical course, Promoting Excellence these enzymes, which are important expertise and quality patient data at in End-of-Life Care. Initiated by to cell growth and development, are New and competitive renewal grants of $50,000 and up are listed here according a to broad areas of research and funding sources. my fingertips—something quite students and developed with the targets of many disease processes, unique for a person with my research Professor of Medicine David M. including cancer. Currently, he is background in chemistry.” Clive, MD, and Professor of Surgery one of three principal investigators H. Brownell Wheeler, MD, the funded through a $6.7 million elective is designed to pair students National Cancer Institute program with terminally ill patients, helping grant to study how genetic them to accept the fact that people information inside the nucleus cancer cell biology genetics die—despite receiving the best of the tumor cell is reorganized american cancer society national institutes of health national institutes of health medical care possible. A follow-up and redistributed and the David A. Hill, PhD, a postdoctoral fellow Stephen J. Doxsey, PhD, associate Rachel M. Gerstein, PhD, assistant program is also offered as a third- consequences of that for cancer’s in the laboratory of Anthony N. Imbalzano, professor of molecular medicine: Centrosome professor of molecular genetics & PhD, assistant professor of cell biology: Assembly and Function, one year, microbiology: Diminished V(D)J year interclerkship to help fledgling onset and progression. Effects of Specific Histone Phosphorylation $280,800; recommended for three more Recombination During B Cell Development, physicians sensitively handle the on Human SWI/SNF Activity, three years, years, $842,400. one year, $78,000. clinical aspects of death, such as “In 1991-1992, umass was $96,000. Elizabeth J. Luna, PhD, professor of cell Michael R. Green, MD, PhD, Howard Marjorie Clay, PhD relieving pain and handling difficult biology: Cytoskeleton/Membrane Hughes Medical Institute Investigator topics, including autopsy request massachusetts department of public health Interactions, one year, $265,460; and professor of molecular medicine: and organ donation. still very young, and this recommended for three more years, $1.1 Mechanisms of Eukaryotic Transcriptional Madelyn R. Schmidt, PhD, research embedding ethics million. Activation, one year, $192,200; Clay concluded, “The UMMS assistant professor of molecular genetics youth was reflected in the Paul R. Odgren, PhD, research assistant recommended for three more years, Professor of Medicine Marjorie A. environment is one in which people & microbiology: A New Gene Therapy Approach professor of cell biology: Trance $576,600. Clay, PhD, was also somewhat of for Prostate Cancer, one year, $75,000. feel free to explore, express and vitality of its researchers Regulation of Chondrocyte Maturation, one Maria L. Zapp, PhD, assistant professor of an enigma when she was hired to dream. The enthusiasm for using national institutes of health year, $253,890; recommended for four molecular genetics & microbiology: Novel establish the Office of Ethics at UMMS. research to improve education made and faculty.” Theodore J. Koh, MD, assistant professor more years, $1 million. Inhibitors of HIV-RNA Protein Interactions, A professor of philosophy, Dr. Clay it easy for me to find room for my of medicine: HB-EGF’s Role in Atrophic one year, $273,000; recommended for says that she was surprised and interests. I’ve never looked back.” Gastritis and Gastric Cancer, one year, $78,209; three more years, $819,000. delighted to be hired to “parent” Peterson noted UMMS’ recruitment recommended for one more year, $78,916. ethics at the Medical School, a research enthusiasm within the last few years of over 30 diabetes & decision she stresses is typical of u.s. army medical research metabolism ever-present new faculty to the basic sciences acquisition activity national institute of diabetes gerontology the flexibility of the institution. And, departments, huge growth Unlike Soller and Clay, Professor Robert E. Carraway, PhD, professor of and digestive and kidney department of health and over the last 10 years, she has worked diseases of Molecular Medicine considering the total number of physiology: Prostate Cancer Cell Growth: human services to embed ethics into every basic department faculty equals about 175. Role of Neurotensin in Mediating Effect of Anthony Carruthers, PhD, professor Craig L. Peterson, PhD, is Jerry H. Gurwitz, MD, the Dr. John Meyers science course and clinical encounter. Dietary Fat and Mechanism of Action, one of biochemistry & molecular the quintessential wet-lab researcher. Yet, more important than this quantity Professor of Primary Care Medicine: Reducing year, $189,034; recommended for two pharmacology: Glucose Transporters Adverse Drug Events in the Nursing Home, As an office of one, Clay focuses Dr. Peterson came to UMMS directly is the quality—UMMS is attracting more years, $395,250. Structure and Function, one year, one year, $590,747; recommended for two most on implementing rather than top-notch faculty, post-doctoral from his postdoctoral training at the Stephen J. Doxsey, PhD, associate $195,000; recommended for four more more years, $1.1 million. fellows and students from premier publishing her research. Any ethical University of California/San Francisco, professor of molecular medicine and German years, $780,000. institutions. “I attribute the success correlation she deems “real and and still speaks today of the A. Pihan, MD, assistant professor of pathology: practical,” she develops as “Ethics unparalleled research environment of my lab to the expansive research Centrosome Defects, Genetic Instability Notes” which are integrated into and sense of excitement he felt growth at UMass, part of Dr. Lazare’s and Prostate Cancer, two years, $777,154. heart disease the preclinical curriculum. She also effort to make it one of the top faculty during the interview process and development national institutes of health creates cards that students can carry upon his arrival. “In 1991-1992, medical schools in the country in James G. Dobson Jr., PhD, professor research. When you recruit and department of health and in their white coats, giving them tips UMass was still very young, and this human services of physiology: Adenosine A1 and A2 work with exceptional colleagues, Receptors in the Myocardium, one year, to handle ethical questions during youth was reflected in the vitality of Mark E. Quirk, EdD, professor of family $348,211; recommended for three more their rotations. “My mission is to it makes you a better scientist— medicine & community health: Faculty its researchers and faculty. Time has years, $1 million; Mechanism of Aging- ensure that physicians are equipped you have to live up to everyone else’s Development in Primary Care, one year, not dampened that spirit.” Enhanced Heart Adenosine, one year, standards, as well as your own.” $633,322; recommended for two more to deal with the ethical dilemmas $274,166; recommended for three more Peterson’s research addresses the years, $1.3 million. inherent in medicine today. That’s years, $833,584. basic questions associated with what drives my research, and I don’t chromatin—the folding of more David S. Newburg, PhD, professor of know of any other medical school biochemistry & molecular pharmacology: than five feet of DNA into that incorporates ethics so readily Endothelial GB3 Species Involved in HUS chromosomes within the cell nucleus. into every part of its curriculum.” Pathogenesis, one year, $136,523; Much of his work, performed in recommended for three more years, yeast, is focused on enzymes that $409,569.

14 Vitae spring - summer 2001 spring - summer 2001 Vitae 15 need for patient care.” In many ways, In addition to her contributions can unfold or remodel the chromatin Soller feels that her position at to the Macy Initiative in Health to allow repair of damaged DNA and UMMS was a precursor to this melding Communication, Clay is well known facilitate the reading of genetic of academic medicine and industry. for her role in the end-of-life material. Peterson’s lab has been “By conducting such investigations curricula, specifically the elective investigating DNA repair and how Gr nts & Research: at a medical school, I have clinical course, Promoting Excellence these enzymes, which are important expertise and quality patient data at in End-of-Life Care. Initiated by to cell growth and development, are New and competitive renewal grants of $50,000 and up are listed here according a to broad areas of research and funding sources. my fingertips—something quite students and developed with the targets of many disease processes, unique for a person with my research Professor of Medicine David M. including cancer. Currently, he is background in chemistry.” Clive, MD, and Professor of Surgery one of three principal investigators H. Brownell Wheeler, MD, the funded through a $6.7 million elective is designed to pair students National Cancer Institute program with terminally ill patients, helping grant to study how genetic them to accept the fact that people information inside the nucleus cancer cell biology genetics die—despite receiving the best of the tumor cell is reorganized american cancer society national institutes of health national institutes of health medical care possible. A follow-up and redistributed and the David A. Hill, PhD, a postdoctoral fellow Stephen J. Doxsey, PhD, associate Rachel M. Gerstein, PhD, assistant program is also offered as a third- consequences of that for cancer’s in the laboratory of Anthony N. Imbalzano, professor of molecular medicine: Centrosome professor of molecular genetics & PhD, assistant professor of cell biology: Assembly and Function, one year, microbiology: Diminished V(D)J year interclerkship to help fledgling onset and progression. Effects of Specific Histone Phosphorylation $280,800; recommended for three more Recombination During B Cell Development, physicians sensitively handle the on Human SWI/SNF Activity, three years, years, $842,400. one year, $78,000. clinical aspects of death, such as “In 1991-1992, umass was $96,000. Elizabeth J. Luna, PhD, professor of cell Michael R. Green, MD, PhD, Howard Marjorie Clay, PhD relieving pain and handling difficult biology: Cytoskeleton/Membrane Hughes Medical Institute Investigator topics, including autopsy request massachusetts department of public health Interactions, one year, $265,460; and professor of molecular medicine: and organ donation. still very young, and this recommended for three more years, $1.1 Mechanisms of Eukaryotic Transcriptional Madelyn R. Schmidt, PhD, research embedding ethics million. Activation, one year, $192,200; Clay concluded, “The UMMS assistant professor of molecular genetics youth was reflected in the Paul R. Odgren, PhD, research assistant recommended for three more years, Professor of Medicine Marjorie A. environment is one in which people & microbiology: A New Gene Therapy Approach professor of cell biology: Trance $576,600. Clay, PhD, was also somewhat of for Prostate Cancer, one year, $75,000. feel free to explore, express and vitality of its researchers Regulation of Chondrocyte Maturation, one Maria L. Zapp, PhD, assistant professor of an enigma when she was hired to dream. The enthusiasm for using national institutes of health year, $253,890; recommended for four molecular genetics & microbiology: Novel establish the Office of Ethics at UMMS. research to improve education made and faculty.” Theodore J. Koh, MD, assistant professor more years, $1 million. Inhibitors of HIV-RNA Protein Interactions, A professor of philosophy, Dr. Clay it easy for me to find room for my of medicine: HB-EGF’s Role in Atrophic one year, $273,000; recommended for says that she was surprised and interests. I’ve never looked back.” Gastritis and Gastric Cancer, one year, $78,209; three more years, $819,000. delighted to be hired to “parent” Peterson noted UMMS’ recruitment recommended for one more year, $78,916. ethics at the Medical School, a research enthusiasm within the last few years of over 30 diabetes & decision she stresses is typical of u.s. army medical research metabolism ever-present new faculty to the basic sciences acquisition activity national institute of diabetes gerontology the flexibility of the institution. And, departments, huge growth Unlike Soller and Clay, Professor Robert E. Carraway, PhD, professor of and digestive and kidney department of health and over the last 10 years, she has worked diseases of Molecular Medicine considering the total number of physiology: Prostate Cancer Cell Growth: human services to embed ethics into every basic department faculty equals about 175. Role of Neurotensin in Mediating Effect of Anthony Carruthers, PhD, professor Craig L. Peterson, PhD, is Jerry H. Gurwitz, MD, the Dr. John Meyers science course and clinical encounter. Dietary Fat and Mechanism of Action, one of biochemistry & molecular the quintessential wet-lab researcher. Yet, more important than this quantity Professor of Primary Care Medicine: Reducing year, $189,034; recommended for two pharmacology: Glucose Transporters Adverse Drug Events in the Nursing Home, As an office of one, Clay focuses Dr. Peterson came to UMMS directly is the quality—UMMS is attracting more years, $395,250. Structure and Function, one year, one year, $590,747; recommended for two most on implementing rather than top-notch faculty, post-doctoral from his postdoctoral training at the Stephen J. Doxsey, PhD, associate $195,000; recommended for four more more years, $1.1 million. fellows and students from premier publishing her research. Any ethical University of California/San Francisco, professor of molecular medicine and German years, $780,000. institutions. “I attribute the success correlation she deems “real and and still speaks today of the A. Pihan, MD, assistant professor of pathology: practical,” she develops as “Ethics unparalleled research environment of my lab to the expansive research Centrosome Defects, Genetic Instability Notes” which are integrated into and sense of excitement he felt growth at UMass, part of Dr. Lazare’s and Prostate Cancer, two years, $777,154. heart disease the preclinical curriculum. She also effort to make it one of the top faculty during the interview process and development national institutes of health creates cards that students can carry upon his arrival. “In 1991-1992, medical schools in the country in James G. Dobson Jr., PhD, professor research. When you recruit and department of health and in their white coats, giving them tips UMass was still very young, and this human services of physiology: Adenosine A1 and A2 work with exceptional colleagues, Receptors in the Myocardium, one year, to handle ethical questions during youth was reflected in the vitality of Mark E. Quirk, EdD, professor of family $348,211; recommended for three more their rotations. “My mission is to it makes you a better scientist— medicine & community health: Faculty its researchers and faculty. Time has years, $1 million; Mechanism of Aging- ensure that physicians are equipped you have to live up to everyone else’s Development in Primary Care, one year, not dampened that spirit.” Enhanced Heart Adenosine, one year, standards, as well as your own.” $633,322; recommended for two more to deal with the ethical dilemmas $274,166; recommended for three more Peterson’s research addresses the years, $1.3 million. inherent in medicine today. That’s years, $833,584. basic questions associated with what drives my research, and I don’t chromatin—the folding of more David S. Newburg, PhD, professor of know of any other medical school biochemistry & molecular pharmacology: than five feet of DNA into that incorporates ethics so readily Endothelial GB3 Species Involved in HUS chromosomes within the cell nucleus. into every part of its curriculum.” Pathogenesis, one year, $136,523; Much of his work, performed in recommended for three more years, yeast, is focused on enzymes that $409,569.

14 Vitae spring - summer 2001 spring - summer 2001 Vitae 15 human development Katherine F. Ruiz de Luzuriaga, MD, physiology american cancer society associate professor of pediatrics: Virus- national institutes of health William E. Theurkauf, PhD, associate Host Dynamics in Early Vertical HIV-1 Lawrence J. Hayward, MD, PhD, assistant professor of molecular medicine: Infection, one year, $76,438; recommended professor of neurology: Molecular Physiology Cytoskeletal Function in Embryonic Axis for three more years, $250,652. of Hyperkalemic Periodic Paralysis, one year, Specification, three years, $750,000. Mario Stevenson, PhD, the David J. $25,452; recommended for two more years, Alumni Rep rt: Freelander Professor of AIDS Research: $208,448. department of health and Analysis of Covert Viral Replication During human services Mitsuo Ikebe, PhD, professor of physiology: HAART, one year, $273,000; recommended Molecular Regulation of Smooth Muscle o Charles D. Hamad, PhD, assistant for four more years, $1.2 million; Role of Actomyosin, one year, $365,021; recommended professor of pediatrics: CED/Distance HIV-1 Gag MA in Viral Entry, one year, for four more years, $1.6 million. Learning, one year, $147,000; $312,000; recommended for four more Carol L. Miller-Graziano, PhD, professor recommended for one more year, years, $1.2 million. $149,900. of surgery: Training in Mechanisms of Trauma Raymond M. Welsh Jr., PhD, professor Pathophysiology, one year, $47,753; national aeronautics and of pathology: Regulation of Natural Killer recommended for four more years, $391,221. space administration Cells, one year, $264,626; recommended Peter J. A. McCaffrey, PhD, assistant for four more years, $1.07 million. professor of cell biology: The Effect of Hypergravity on Retinoic Acid Signaling psychiatry in the Developing Embryo, one year, national institutes of health $138,413; recommended for two more neurobiology Kenneth E. Fletcher, PhD, assistant professor years, $297,795. national institutes of health of psychiatry: Outpatient Treatment of Juvenile Athena Andreadis, PhD, associate Sexual Offenders, one year, $193,352; national institutes of health a message from the chancellor dean professor of cell biology: TAU in recommended for two more years, $383,436. / Joel D. Richter, PhD, professor of Frontoemporal Dementia: Regulation molecular genetics & microbiology: of Exon 10, one year, $275,050; Each day, our students, faculty and staff strive towards national distinction in education, research and public service. Because of Cell Biology of Development, one year, recommended for four more years, this, UMMS is continually recognized for numerous accomplishments—this spring, UMMS ranked fourth in the nation in U.S.News $128,292; recommended for four more $1.1 million. years, $513,168. radiology and digital & World Report's list of the Top Medical Schools—Primary Care. Our medical students continue to excel; this spring at Match Day, Jose R. Lémos, PhD, professor of imaging 63 percent of students received their first choice of residency; 90 percent one of their top four choices. Our innovative faculty lead physiology: Depolarization-Secretion national institutes of health Coupling in Nerve Terminals, one year, America’s medical schools in curriculum and educational research, as exemplified by the highest aggregate number of presentations Walter A. Carrington, PhD, associate professor $310,880; recommended for three more of any school at last fall’s annual meeting of the Association of American Medical Colleges. of physiology: High Resolution 4-Dimensional infectious diseases years, $936,000. & immunology Fluorescence Microscopy, one year, $269,806; In the field of research, the National Institutes of Health granted our investigators an additional $13 million in funding over last year Richard B. Vallee, PhD, the H. Arthur recommended for two more years, $545,505. department of health and to advance their research into the causes of and cures for disease. With this 22 percent increase, we have surpassed the $100 million Smith Chair in Cancer Research: Mechanism human services Andrew Karellas, PhD, professor of radiology: mark in overall research funding. of Action of the Lissencephaly Genes Lis1, Donna M. Gallagher, MSN, instructor High Resolution Cardiovascular Flat-Panel X-ray one year, $320,760; recommended for four All members of the UMMS community, both internally and externally, through our alumni, are committed to the public service in family medicine & community health: Imager, one year, $623,666; recommended for more years, $1.1 million; Training Grant in National AIDS Education and Training three more years, $1.2 million. component of our mission. We see the results of their commitment to improving their cities and towns for schoolchildren, the Cellular and Molecular Neurobiology, one underserved and the homeless every day. Center Grants, one year, $936,001; Michael A. King, PhD, professor of radiology: year, $158,143; recommended for four recommended for one more year, $890,434. Digital Restoration of SPECT Images for Tumor more years, $632,572. Many of our alumni have shown distinction in their own careers, and I am pleased to introduce you to three who are serving as Detection, one year, $345,113; recommended national institutes of health inspiration for all of us to continue to carry our mission to its fulfillment: for four more years, $1.4 million. Diane R. Blake, MD, assistant professor Shan Lu, a 1991 Graduate School of Biomedical Sciences alumnus and associate professor of medicine at UMMS, is on the of pediatrics: Non-invasive Chlamydial threshold of developing a vaccine strategy for HIV. Dr. Lu is just one example of the caliber of researchers at the Medical School Screening for Adolescents, one year, pharmacology and the exceptional education students receive here, which lays the foundation for potentially life-saving breakthroughs. $131,490; recommended for four more national institutes of health years, $525,960. Steven N. Treistman, PhD, professor of Elizabeth McGrath, Graduate School of Nursing class of 1999, is a tireless advocate for the health of the homeless members Sharone Green, MD, associate professor biochemistry & molecular pharmacology: of her community, serving as the Providence Traveler's Aid Society staff nurse while continuing her surgical intensive care nursing of medicine: Human Immune Responses Alcohol Action on Nerve Terminals and Cell career at Rhode Island Hospital and her nurse practitioner position in private practice. Her dedication to caring and support for those Bodies, one year, $326,378; recommended to Yellow Fever Virus, one year, $117,450; in need is a source of pride for the GSN and the entire UMMS community. recommended for four more years, $470,470. for four more years, $1.4 million. Mary Jean Stempien, School of Medicine class of 1988, is a physician in industry, designing development programs for John E. Herrmann, PhD, professor of smokeless tobacco research potential new medicines and then facilitating the clinical trials required to bring those promising drugs to market. At Roche, she has medicine: Development of Rotavirus DNA council helped to establish drugs that treat infections in AIDS and transplant patients, ensuring the future health—as Lu and McGrath do— Vaccines, one year, $337,920; recommended Paul D. Gardner, PhD, associate professor for two more years, $641,120. of psychiatry: Regulation of Nicotinic of people within our neighborhoods and across the globe. Acetylcholine Receptor Gene Expression, one year, $66,713. Aaron Lazare, MD

16 Vitae spring - summer 2001 spring - summer 2001 Vitae 17 human development Katherine F. Ruiz de Luzuriaga, MD, physiology american cancer society associate professor of pediatrics: Virus- national institutes of health William E. Theurkauf, PhD, associate Host Dynamics in Early Vertical HIV-1 Lawrence J. Hayward, MD, PhD, assistant professor of molecular medicine: Infection, one year, $76,438; recommended professor of neurology: Molecular Physiology Cytoskeletal Function in Embryonic Axis for three more years, $250,652. of Hyperkalemic Periodic Paralysis, one year, Specification, three years, $750,000. Mario Stevenson, PhD, the David J. $25,452; recommended for two more years, Alumni Rep rt: Freelander Professor of AIDS Research: $208,448. department of health and Analysis of Covert Viral Replication During human services Mitsuo Ikebe, PhD, professor of physiology: HAART, one year, $273,000; recommended Molecular Regulation of Smooth Muscle o Charles D. Hamad, PhD, assistant for four more years, $1.2 million; Role of Actomyosin, one year, $365,021; recommended professor of pediatrics: CED/Distance HIV-1 Gag MA in Viral Entry, one year, for four more years, $1.6 million. Learning, one year, $147,000; $312,000; recommended for four more Carol L. Miller-Graziano, PhD, professor recommended for one more year, years, $1.2 million. $149,900. of surgery: Training in Mechanisms of Trauma Raymond M. Welsh Jr., PhD, professor Pathophysiology, one year, $47,753; national aeronautics and of pathology: Regulation of Natural Killer recommended for four more years, $391,221. space administration Cells, one year, $264,626; recommended Peter J. A. McCaffrey, PhD, assistant for four more years, $1.07 million. professor of cell biology: The Effect of Hypergravity on Retinoic Acid Signaling psychiatry in the Developing Embryo, one year, national institutes of health $138,413; recommended for two more neurobiology Kenneth E. Fletcher, PhD, assistant professor years, $297,795. national institutes of health of psychiatry: Outpatient Treatment of Juvenile Athena Andreadis, PhD, associate Sexual Offenders, one year, $193,352; national institutes of health a message from the chancellor dean professor of cell biology: TAU in recommended for two more years, $383,436. / Joel D. Richter, PhD, professor of Frontoemporal Dementia: Regulation molecular genetics & microbiology: of Exon 10, one year, $275,050; Each day, our students, faculty and staff strive towards national distinction in education, research and public service. Because of Cell Biology of Development, one year, recommended for four more years, this, UMMS is continually recognized for numerous accomplishments—this spring, UMMS ranked fourth in the nation in U.S.News $128,292; recommended for four more $1.1 million. years, $513,168. radiology and digital & World Report's list of the Top Medical Schools—Primary Care. Our medical students continue to excel; this spring at Match Day, Jose R. Lémos, PhD, professor of imaging 63 percent of students received their first choice of residency; 90 percent one of their top four choices. Our innovative faculty lead physiology: Depolarization-Secretion national institutes of health Coupling in Nerve Terminals, one year, America’s medical schools in curriculum and educational research, as exemplified by the highest aggregate number of presentations Walter A. Carrington, PhD, associate professor $310,880; recommended for three more of any school at last fall’s annual meeting of the Association of American Medical Colleges. of physiology: High Resolution 4-Dimensional infectious diseases years, $936,000. & immunology Fluorescence Microscopy, one year, $269,806; In the field of research, the National Institutes of Health granted our investigators an additional $13 million in funding over last year Richard B. Vallee, PhD, the H. Arthur recommended for two more years, $545,505. department of health and to advance their research into the causes of and cures for disease. With this 22 percent increase, we have surpassed the $100 million Smith Chair in Cancer Research: Mechanism human services Andrew Karellas, PhD, professor of radiology: mark in overall research funding. of Action of the Lissencephaly Genes Lis1, Donna M. Gallagher, MSN, instructor High Resolution Cardiovascular Flat-Panel X-ray one year, $320,760; recommended for four All members of the UMMS community, both internally and externally, through our alumni, are committed to the public service in family medicine & community health: Imager, one year, $623,666; recommended for more years, $1.1 million; Training Grant in National AIDS Education and Training three more years, $1.2 million. component of our mission. We see the results of their commitment to improving their cities and towns for schoolchildren, the Cellular and Molecular Neurobiology, one underserved and the homeless every day. Center Grants, one year, $936,001; Michael A. King, PhD, professor of radiology: year, $158,143; recommended for four recommended for one more year, $890,434. Digital Restoration of SPECT Images for Tumor more years, $632,572. Many of our alumni have shown distinction in their own careers, and I am pleased to introduce you to three who are serving as Detection, one year, $345,113; recommended national institutes of health inspiration for all of us to continue to carry our mission to its fulfillment: for four more years, $1.4 million. Diane R. Blake, MD, assistant professor Shan Lu, a 1991 Graduate School of Biomedical Sciences alumnus and associate professor of medicine at UMMS, is on the of pediatrics: Non-invasive Chlamydial threshold of developing a vaccine strategy for HIV. Dr. Lu is just one example of the caliber of researchers at the Medical School Screening for Adolescents, one year, pharmacology and the exceptional education students receive here, which lays the foundation for potentially life-saving breakthroughs. $131,490; recommended for four more national institutes of health years, $525,960. Steven N. Treistman, PhD, professor of Elizabeth McGrath, Graduate School of Nursing class of 1999, is a tireless advocate for the health of the homeless members Sharone Green, MD, associate professor biochemistry & molecular pharmacology: of her community, serving as the Providence Traveler's Aid Society staff nurse while continuing her surgical intensive care nursing of medicine: Human Immune Responses Alcohol Action on Nerve Terminals and Cell career at Rhode Island Hospital and her nurse practitioner position in private practice. Her dedication to caring and support for those Bodies, one year, $326,378; recommended to Yellow Fever Virus, one year, $117,450; in need is a source of pride for the GSN and the entire UMMS community. recommended for four more years, $470,470. for four more years, $1.4 million. Mary Jean Stempien, School of Medicine class of 1988, is a physician in industry, designing development programs for John E. Herrmann, PhD, professor of smokeless tobacco research potential new medicines and then facilitating the clinical trials required to bring those promising drugs to market. At Roche, she has medicine: Development of Rotavirus DNA council helped to establish drugs that treat infections in AIDS and transplant patients, ensuring the future health—as Lu and McGrath do— Vaccines, one year, $337,920; recommended Paul D. Gardner, PhD, associate professor for two more years, $641,120. of psychiatry: Regulation of Nicotinic of people within our neighborhoods and across the globe. Acetylcholine Receptor Gene Expression, one year, $66,713. Aaron Lazare, MD

16 Vitae spring - summer 2001 spring - summer 2001 Vitae 17 researching the promise of an hiv vaccine ‘a little advocacy’ goes a long way

Ten years ago, Shan Lu, MD, PhD, When his fellowship ended in 1995, Most days, you might have a hard time Nursing. Today, she juggles her two was speaker of his graduating class at Lu sought a way to connect his basic tracking down Elizabeth McGrath, part-time jobs, devotes every Friday to UMMS’ Graduate School of Biomedical research to people, applying vaccines RN, ANP ’99. the soup kitchen (where she's been a Sciences (GSBS). A decade later, he is to healthy populations. He entered volunteer for more than 25 years, and She works 24 hours a week as a still at UMMS—with an international the Clinical Scientist Pathway residency its cook for the last 10), and spends a surgical intensive care nurse at Rhode reputation for his pioneering work in program at UMMS, spending three good deal of time helping to arrange Island Hospital, and part-time as a the search for an HIV vaccine. years in clinical training in internal doctors’ appointments and find housing, nurse practitioner in the Providence medicine while building his own lab and even distributing items from her car to His achievements had their roots in China. office of a physician who specializes in later conducting research that captured the homeless. cardiology and geriatrics. Every Friday, Dr. Lu was a resident in the Department attention in the HIV vaccine field. however, you’ll find her at the soup “These people have no health of Medicine of the First Affiliated Hospital Today, Lu bridges the worlds of patient kitchen run by the Providence Intown insurance, no money for medications, at Nanjing Medical College in the care and cutting-edge biomedical Churches Association, where she cooks no phones to make doctors’ appoint- mid-1980s when his native country’s research. He is associate professor dinner for as many as 200 people ments,” she explained. “Advocacy is new open-door policy afforded him an of medicine at UMMS and attending struggling with homelessness, poverty, important for them; just imagine being opportunity to study abroad. A PhD physician in the Division of Primary Care mental illness and what McGrath calls put on hold at a pay phone. Twenty-five candidate, Lu enrolled in the GSBS in & General Medicine at UMass Memorial “inner loneliness.” cents doesn’t last too long. And there’s 1985, earning his doctorate in Health Care. He and project partner nowhere to call them back. immunology in 1991. McGrath has been a nurse “for more Advanced BioScience Laboratories Accompanying someone to a doctor’s years than I care to admit.” She worked “My wife and I planned to return recently were awarded an HIV Vaccine appointment can be incredibly helpful. full-time at Rhode Island Hospital until to China when I completed graduate Design and Development Team (HVDDT) 1987, helping to launch an open-heart “This is a population that can really use school,” said Lu. “But then the research contract from the NIH. The NIH unit there, which she headed for several nurses,” she continued. “And in their Tian’anmen Square Student Movement has committed approximately $70 million years. “The job was all-consuming; own way, they seem to respond to people happened, and we decided to stay here over the next five years to just four I never saw the light of day,” she recalled, who care about them. for my post-doctoral work.” It was a public-private partnerships worldwide but she did find time to volunteer in life-changing decision. to help accelerate the development It’s about so much more than the a free medical van that traveled the of promising HIV vaccines. material things; it’s about the marvel Lu joined the UMMS Department of streets of Providence. of discovering who each individual truly Pathology as a post-doctoral research Lu also is directing a two-year multi- Her volunteer work increased her is inside, and how a little advocacy can fellow in 1991. In 1992, he was awarded center human clinical trial at UMMS, in awareness that there was much to do help them become more fully aware of a prestigious Howard Hughes Medical conjunction with clinical partner UMass in order to help address the health care their place in the world.” — rj Institute Post-doctoral Fellowship to Memorial Health Care, to test an Shan Lu, MD, PhD ’91 needs of the homeless. McGrath cut Elizabeth McGrath, RN, ANP ’99 develop novel HIV vaccines. In the experimental HIV vaccine developed by back to part-time hours at the hospital following years, he and his then mentor, Merck & Co., and its ability to stimulate and began work with the Travelers’ Aid Dr. Harriet Robinson, demonstrated the protective immune responses in the Society, which provides a full range of feasibility of a whole new vaccination body. UMMS is one of 12 sites taking health and social services, as well as technology which is becoming the main part in this landmark study. information and referral, for homeless tool many HIV vaccine researchers are Lu attributes UMMS’ commitment to persons. In the early 1990s, she became currently using. biomedical research to helping make the society’s staff nurse. his achievements in the field possible, McGrath’s work—and the needs of the noting how the institution's recruitment population she worked with—spurred of top-notch researchers continues her to go back to school to become a to attract many talented scientists. nurse practitioner. In 1999, she received “Every time I invite a speaker here, her degree from the Graduate School of they’re amazed at the caliber of the team UMMS has assembled.” — rj

18 Vitae spring - summer 2001 spring - summer 2001 Vitae 19 researching the promise of an hiv vaccine ‘a little advocacy’ goes a long way

18 Vitae spring - summer 2001 spring - summer 2001 Vitae 19 Class N tes: helping patients on a global scale o

“When I started working in industry, I would get a PhD in pharmaceutical 1983 it wasn't a popular choice,” said science, and went to graduate school Howard N. Fixler, MD, is chief of internal Mary Jean Stempien, MD ’88, for a couple of years. But I found myself medicine at Fairlawn Rehabilitation Hospital director of medical research for Roche drawn to the clinical side.” She decided in Worcester, where he previously served Pharmaceuticals in Palo Alto, Calif. to go to medical school. as medical director. In addition to his “But these days I find more physicians 1978 1990 A self-proclaimed “product of public position at Fairlawn, Dr. Fixler is associate are looking at the opportunities that chief medical officer for post acute care for education,” Stempien zeroed in on Ethan Russo, MD, recently published Tad Baum, MD, opened his new practice industry offers.” the Handbook of Psychotropic Herbs: UMass Memorial Health Care. in Groton, Mass. A board-certified the state’s only public medical school, A Scientific Analysis of Herbal Remedies ophthalmologist and LASIK surgeon, At Roche since 1992 (then Syntex UMMS, which provided her with an for Psychiatric Conditions, available from 1986 Dr. Baum completed his residency at the Research), Dr. Stempien helps design exceptional education and the flexibility Haworth Press. A neurologist in Missoula, Anne Cushing-Brescia, MD, is a member New York Medical College, earning a clinical development programs for of completing her fourth-year electives Mont., Dr. Russo also serves as the editor- of the Department of Emergency Medicine fellowship in LASIK Vision Correction at potential new medicines. “I have the in California, where her physician husband in-chief of the Haworth Integrative Healing at Saint Anne’s Hospital in Fall River, Mass. the Massachusetts Eye and Ear Infirmary. Press, a book program dedicated to the opportunity to interact with basic had secured employment following A diplomate of the American Board of Susan A. Mangini, MS, RN, NP, is vice science researchers who are looking completion of his surgical training at scientific investigation of alternative and Internal Medicine, Dr. Cushing-Brescia is president of patient care services at Milton complementary medicine. for new molecules for potential drug Boston University and Lahey Clinic. also a clinical instructor in medicine at (Mass.) Hospital, responsible for managing development,” she explained. As the Brown University School of Medicine. all aspects of nursing services. Prior to her After serving her own residency in 1979 physician member of a cross-functional current position, Mangini served as the internal medicine at the California Pacific Robert M. Haddad, MD, is president of 1987 nursing director of perioperative and project team, she then helps design and Medical Center in San Francisco, St. Elizabeth’s Medical Center in Brighton, ambulatory care services at Day Kimball supervise the clinical trials required to Murray C. Norcross Jr., MD, is a family Stempien faced a choice between going Mass. St. Elizabeth’s is the flagship practice physician in the U.S. Navy, Hospital in Putnam, Conn. establish safety and efficacy and bring into practice or research. “I could have institution of Caritas Christi, a Catholic stationed at the Naval Hospital in Yokosuka, a promising new drug to market. been happy in practice, but I was still health care system that runs six hospitals Japan. “I serve as director of clinical 1991 in the Boston area. Prior to his appointment, Stempien’s achievements include the intrigued by the clinical research area, services for a 95-bed community hospital Stephen J. Barr, MD, was inducted as Dr. Haddad was senior vice president of successful development of two drugs so I decided to explore that first.” which supports the United States Seventh a fellow of the American Academy of clinical practice and business strategy at Fleet and its families. My wife Ann and used to treat cytomegalovirus (CMV) Orthopaedic Surgeons during ceremonies Nine years later, Stempien says of her Geisinger Health System in Danville, Pa. children, Monika and Nathaniel, have at the academy’s 68th annual meeting in infections in AIDS and transplant decision, “In clinical practice, a physician joined me here for this assignment.” San Francisco. Dr. Barr practices with Maine patients: Ganciclovir and Valganciclovir. has individual interactions with patients, 1980 Orthopaedic Center and specializes in “I’m very proud of Valganciclovir,” she and that's very rewarding. You can still Michael J. DeLeo Jr., MD, and his two 1988 general, hand and spine orthopedic surgery. stated. “It has recently been approved maintain that good feeling working in partners at Berkshire Hematology Oncology Nathaniel G. Clark, MD, an adult and Kelton Burbank, MD, has joined the in the U.S. and is the first oral agent opened their new cancer care center in industry; it's just on a more global level, pediatric endocrinologist, was awarded Heywood Hospital staff after completing effective as initial treatment of AIDS- Pittsfield, Mass. in June 2000. A significant Mary Jean Stempien, MD ’88 since you can work on something that the Vermont Dietetic Association Pyramid his residency in orthopedic surgery at UMMS. related CMV retinitis.” She also was portion of the center is devoted to Award in July 2000 for his contribution to Prior to becoming an orthopedic surgeon, can ultimately benefit many thousands chemotherapy infusion and research. involved in the clinical development of nutrition education in the state. As a new Dr. Burbank practiced family medicine at of patients around the world.” — rj Dr. DeLeo lives in Pittsfield with his wife Mycophenolate, a drug used to prevent member of the staff at Falmouth (Mass.) the Winchendon (Mass.) Health Center. Marka and their four children. Hospital, Dr. Clark has a special interest in acute rejection in transplant recipients. Brian P. Sutton, MD, was named the adult and pediatric diabetes, thyroid Hamden County EMS, “Physician of the 1981 Stempien began her career as a disorders and growth disorders in children. Year,” for his outstanding achievement in hospital pharmacist, which included Tania Lingos, MD, is medical director of Kim D. Houde, MD, served as Master of emergency medicine at Noble Hospital in a pharmacy supervisor position at Brigham the South Suburban Oncology Center in Ceremonies at the second annual Native Westfield, Mass. & Women’s Hospital. “My hospital Quincy, Mass. and is on the staff of South American Health Conference, “Closing the Shore Hospital, Quincy Hospital, Good work and interactions with physicians Circle.” The conference, developed for Samaritan Hospital and Massachusetts increased my interest in clinical research, health care professionals who serve the General Hospital. Native American community, featured drug development and medicine. I thought workshops on specific issues affecting Native American health, as well as combining Western medicine with traditional healing practices. Dr. Houde is a member of the Seneca Tribe and an assistant professor of family medicine & community health at UMMS.

20 Vitae spring - summer 2001 spring - summer 2001 Vitae 21 Class N tes: helping patients on a global scale o

20 Vitae spring - summer 2001 spring - summer 2001 Vitae 21 To submit a class note, send your news to:

Alumni and Parents Relations Office, University of Massachusetts Medical School I 55 Lake Avenue North I Worcester, MA 01655

or e-mail [email protected] call (508) 856 8300 or (508) 856 3372 fax (508) 856 5490

alumni association scholarship dinner 1994 1996 1997

Kristen Lee Dardano, MD, assistant Joseph Bouvier, MD, is a pediatrician in Brian Dalton, MD, is a member of the staff professor at Tufts University School of Mesa, Ariz. He is married to Andrea (Masiero) of Jordan Hospital in Plymouth, Mass. as Medicine—Baystate Medical Center, Bouvier, whom he met while on rotation at a specialist in internal medicine. was one of 20 scholars selected for the Berkshire Medical Center. The Bouviers Lisa Noble, MD, practices family medicine, Associate of Professors of Gynecology celebrated the birth of their first child, with a special interest in women’s health Kristin Farrell ’03, recipient of the Linda Goudey, MD, Memorial V-P/ Treasurer Andrew J. Miller ’79 and his wife Tina Scholarship, and Marguerite Rafuse, Dr. Goudey's mother and Obstetrics/Solvay Pharmaceuticals Samantha Michelle, in the fall of 2000. and complementary medicine, with the UMass Educational Scholars Development Jose Guerra, MD, is a member of Memorial Medical Group in Worcester. Program. The program is the first-ever, Winchester (Mass.) Family Physicians. comprehensive educational curriculum Gregory K. Steinberg, MD, joined the After completing his residency in family emergency medical team at Milford- designed to improve education in practice at the University of Washington- obstetrics and gynecology. Dr. Dardano, Whitinsville Regional Hospital, after completing Providence in Seattle, Dr. Guerra served as his residency at UMMS, where he served inducted in January as a member of the a clinical instructor in family medicine at 2001-2002 class of scholars, will take as a LifeFlight physician since 1998. Boston University and Boston Medical Center Hoagland-Pincus Center part in the program designed to help before joining Winchester. His areas of Stephanson Bernard Tobierre, MD, is a obstetricians and gynecologists become interest are sports medicine and pediatrics. family practice physician at the Joseph M. better scholars and leaders in the field Smith Community Health Center in Allston, October 2000 of women’s health. She was selected from Laurie A. Gumuchian, MD, is medical Mass. In addition to seeing patients at a group of applicants from across the U.S. director of the Women’s Health Network of the center, Dr. Tobierre plans to participate based on her credentials and demonstrated Hallmark Health, acting as a resource for in a number of youth programs, including commitment to women’s health education. the network’s program staff and physician the Keep Teens Healthy Project, which Program graduates are expected to share providers, and serving as a facilitator for aims to provide education and services the knowledge gained from this program a number of Women’s Health Network to at-risk teens in Allston, Brighton and within their communities. Dardano develops programs, including the Well Women’s Project surrounding communities. the primary care curriculum for residents and the Breast and Cervical Cancer Initiative. at Baystate Medical Center in Springfield, In addition to her duties as medical director, Mass. In addition, she is the clerkship Dr. Gumuchian provides comprehensive director for medical students and assistant medical care at her practice, Family medical director for midwife practice. Healthcare Associates of Everett, Mass.

in the past 18 years, the alumni alumni and parents relations: upcoming events association has awarded over $375,000

in scholarships and loans to deserving

umms students. august september october

13 15 13 Alumni Association award recipients join President Irvin Heifetz, MD ’79 and V-P/Treasurer Andrew Miller, MD ’79. They are, from left to right: Kathleen McGraw ’01; David Carlson ’03; William Porcaro ’02; Cynthia L. Walenziewicz ’04; Carole Smith ’01; Parents of Medical Students Reunion for 5, 10, 15 and 20-year 25-year School of David Dredge ’04; Daniel Osuch ’04; Meaghan Connors ’03; Payal Patel ’04; and Kristin Farrell ’03. Orientation Luncheon and Program School of Medicine classes Medicine Class Reunion

22 Vitae spring - summer 2001 spring - summer 2001 Vitae 23 To submit a class note, send your news to:

Alumni and Parents Relations Office, University of Massachusetts Medical School I 55 Lake Avenue North I Worcester, MA 01655

or e-mail [email protected] call (508) 856 8300 or (508) 856 3372 fax (508) 856 5490

alumni association scholarship dinner 1994 1996 1997

in the past 18 years, the alumni alumni and parents relations: upcoming events association has awarded over $375,000

in scholarships and loans to deserving

umms students. august september october

22 Vitae spring - summer 2001 spring - summer 2001 Vitae 23 25-year school of medicine reunion Development Update:

This section’s stories represent snapshots of people from all walks of life, who have given of themselves through their support of the UMass Memorial Foundation. We are grateful to these remarkable individuals for the October 2000 character they have shown, often in the face of adversity, to bring hope to those who Higgins Armory Museum battle the devastating diseases of our time.

Kevin G. Courtney Associate Vice Chancellor for Development

Lisa Ling and Tony Saizon at the Boston Marathon Mary and Gene DeFeudis, right, tour the atrium construction area Mary Tse, MD ’77 and Lorraine Bello, MD ’77 Muriel Sawyer, retired UMMS Alumni Affairs director; Frank Chlapowski, PhD, with Chair of Medicine Robert Finberg, MD, and Chancellor Aaron Lazare. and his wife Susan; and Theodora Christopher, MD ’75 marathon effort benefits pediatric defeudises contribute major cancer research and treatment leadership gift The atria in the new research laboratory A test of the will to endure, when pain and the mind join forces to bring about surrender. building are designed to connect lab The Boston Marathon is not about life and death—not like cancer can be—but the battle floors, promoting collaboration and to conquer the most famous run in the world and the world’s most treacherous disease was community, or “research neighborhoods,” the focus of a dedicated group who raised over $100,000 for the Ali Pierce Endowment Fund. to use the architect’s phrase. In honor of Lisa Ling, Tony Saizon and members of Ali & Dad’s Army completed the 26.2-mile marathon their major leadership gift to the Campaign

Craig Van Roekens, MD ’90; Adam Altman, MD ’85; Nada and Chris Wheelock, MS ’04, and their son, Ryan with a purpose that drove them to the finish line and to a new level of contribution to the for Research, the Grand Atrium, which Barry Malloy, MD ’85; and Anthony Wilson, MD ’90 fund, which supports pediatric cancer research at UMass Medical School and cancer care connects floors 1 through 3, has been programs at UMass Memorial Health Care. Ling, a popular daytime talk show co-host, ran named in honor of Gene and Mary DeFeudis. as the honorary “Ali” of the 10-member team. Saizon ran as “Dad.” “From the day my cousin Collaboration, community and neighbor- Ali died of liver cancer, I wanted to do something,“ said Ling. “When Ali & Dad’s Army secured hood are words that are at the foundation slots in the Boston Marathon, I had my calling. I determined that whether I had to run, walk of the DeFeudis Family’s philanthropy. or crawl, I was going to finish the job.” Gene DeFeudis was born and raised Saizon spoke of his inspiration to complete the grueling course—Ali’s father, John Pierce. October 2000 in Worcester and played just a stone’s “John’s idea to run the Marathon to raise funds for Ali’s endowment continues through us throw from the present site of UMass Hoagland-Pincus Center after his untimely death less than a year after Ali’s,” said Saizon, whose mother and father Medical School. He met Mary Streeter, succumbed to cancer, as did his sister. Now, his focus is on the battle his brother is and UMMS campus also a Worcester native who grew up in waging against the disease. Sterling, and together they raised their Experts at the UMass Cancer Center are focused on improved means of detection, son and daughter in Northborough, therapy and cure for afflicted children. The fund supports the Ali Pierce Integrative appreciating the sense of community that Treatment Program, comprised of four components: non-traditional treatment, resides in Central Massachusetts. experimental treatment, professional health care staff training and Project Hope, which Mr. DeFeudis founded and successfully addresses the psychological and behavioral issues that may arise in families when a child guided lending and real estate development is in remission or suffers a relapse, by providing professionally guided parent support firms, including Forward Financial Company groups and resource materials. reunion for 5, 10, 15 and 20-year school and his current firm, Ellsmere Investment For information on supporting the Ali Pierce Endowment Fund and pediatric Company. And, both he and Mrs. DeFeudis cancer research at UMMS, contact Jenique Radin at (508) 856-2553, or log on struggled with the impact of cancer, which of medicine classes and family day to www.umassmed.edu/foundation/alianddad. stole the lives of his brother and her father.

(continued next page)

24 Vitae spring - summer 2001 spring - summer 2001 Vitae 25 25-year school of medicine reunion Development Update:

Kevin G. Courtney Associate Vice Chancellor for Development

(continued next page)

24 Vitae spring - summer 2001 spring - summer 2001 Vitae 25 Campaign for Research Chairwoman Nancy Feldman and Chancellor (DeFeudises, continued) Lazare at the Campaign for Research Gala. Funds raised will help construct the research laboratory building, where the Mass. AFL-CIO Their major leadership gift to the Campaign for Research will significantly influence the Cancer Research Center will be housed. future of cancer investigations at UMMS, the institution that grew out of the playing fields of Mr. DeFeudis’ youth. With their generous contribution, the DeFeudises bring their financial support, their dedication to their community and their determination to finding walk to cure cancer a cure for cancer. “This horrible disease of cancer touches so many families, so many ummf initiates continues to aim high ™ lives, and we feel fortunate to be able to offer our support,” said Mrs. DeFeudis. Her leave a legacy Motivation. It springs from many sources husband added: “It is vital to us that a cure is found for this dread disease. We have very What percentage of Americans have and drives the success of the Walk to Cure Gala Emcees Peter Mehegan strong feelings for this community and want to give back.” created a will or trust that leaves Cancer, now in its third year. This Labor Day, of WCVB Channel 5 and bequests to the charitable causes they September 3, some 8,000 motivated walkers Lisa Ling of ABC daytime television support? Though an estimated 70 percent are expected to raise an unprecedented $750,000 for the Massachusetts AFL-CIO Cancer of households nationwide contribute to Research Center, to be housed on two floors of the new research laboratory building. Sarah Stone, MD charity each year, just under six percent At last year’s walk, for example, members of the UMMS School Fiscal Department were our time to lead of them grant a charitable bequest inspired to create Walk to Cure Cancer buttons that staff sold for $1 each. Proud of their through planned giving. This small Amidst the lights, music and celebratory handshakes of friends and colleagues, the Gala fund-raising accomplishment, “Team Fiscal” is challenging departments from both the percentage of bequests is mirrored by for the Campaign for Research served to honor the exceptional growth of the UMass Medical Medical School and UMass Memorial Health Care to participate in 2001. According to walk the relatively few dollars bequeathed— School basic and clinical research enterprise, the leaders and scientists that laid forth the organizers, if half of all employees walked, 5,000 pairs of feet would be traveling around less than eight percent of total gift vision that has hastened its growth, and the donors whose unselfish desire to bring an the banks of Lake Quinsigamond—and into the hearts of cancer victims and their families. end to disease will help put it in its proper place—the new research laboratory building. amounts nationwide. Each year, the number of businesses that have sent teams to the walk has increased. From In an effort to educate current and The Campaign for Research, designed to accelerate the growth of the biomedical research small operations, like Paul’s Center Bakery in Millbury, to Fortune 500 corporations like potential donors about the advantages enterprise through the recruitment of 100 new research faculty and the construction and professorship EMC, front and center on the world economic stage, the incentive to help is easily tapped. outfitting of the Medical School’s research building, moved into its public phase on May 5 honors the memory of charitable giving through bequests, Their enthusiasm is shared by the researchers and clinicians whose programs of with the Gala Celebration at Worcester’s Centrum Centre. of gifted faculty the UMass Memorial Foundation has member become a member of Leave A Legacy™, investigation and treatment will be supported in part by funds raised at the walk. Until May, campaign efforts had focused on securing the leadership gifts that are critical Robert Finberg, MD, the Richard M. Haidack Professor and Chair of Medicine, researches Sarah L. Stone, MD, 44, professor of a community-based program that to achieving the campaign’s $38 million goal. With the May kick-off, the public at large was the connection between the mechanisms of infectious disease and the causes of cancer, medicine at UMass Medical School and advocates charitable giving through a invited to participate in the campaign. and walks with cancer survivors and their families and UMass Cancer Center patients, a general internist at UMass Memorial will or from an estate. The nationwide investigators and staff. All are encouraged by the commitment of the Massachusetts Emcees Peter Mehegan of Channel 5’s “Chronicle,” and father of School of Medicine Health Care, died at home in Natick, Mass. program is a cooperative effort of a AFL-CIO, which, under the motivating force of President Robert J. Haynes, pledged to graduate Kathryn Mehegan, MD, and Lisa Ling, popular daytime talk show co-host and on February 5, 2001, of ovarian cancer. variety of nonprofit groups, including niece of Anna Ling Pierce, founder of Ali & Dad’s Army, introduced speakers and honored educational and health care institutions, raise $5 million through the annual walk. Dr. Stone joined the UMMS faculty in guests to the approximately 300 attendees. “The incredible generosity of our donors social service and cultural organizations Members of unions within the AFL-CIO, such as Mailhandlers Local 301, rise to the 1986 and had a distinguished career as ™ ensures the ultimate success of the Campaign for Research,” said Campaign Chair Nancy and churches. The Leave a Legacy Haynes challenge in increasing numbers each year. Mary Ellen Winkelman, a UMMS a leader in medical education and clinical Edman Feldman. “I am pleased to report that $22 million has been raised over the past program was initiated in Central mailhandler who helps organize teams for the walk, finds that so many of her “brothers care. She served as the director of the 22 months—58 percent of our goal. It is all of you who have made this possible.” Mrs. Massachusetts through the work of and sisters are touched by cancer in some way that it has opened their eyes to this Division of Primary Care and General Feldman acknowledged leadership donors Sarah M. Adams, Gene and Mary DeFeudis, a committee of representatives from cause.” Winkelman, a breast cancer survivor, believes she “puts a face” to the disease, Medicine in the Department of Medicine Barbara and Nathan Greenberg, the late Milton P. and Alice C. Higgins, Dr. and Mrs. Arthur local foundations, including the UMMF, encouraging participation in the walk. On Labor Day 2001, the numbers will back that up. and as associate chair of the Department M. Pappas, the H. Arthur Smith Charitable Foundation and Jack and Shelley Blais, who colleges and universities, civic of Medicine. Dr. Stone was director of the For more information about the 2001 Walk to Cure Cancer, contact Cathy LaRocca, that evening made a surprise announcement that they were contributing an additional organizations and service agencies, Center for Community Faculty event manager, at (508) 856-1634. $2 million to the Campaign, bringing their gift to $5 million. joined by professional financial advisors. Development, and creator and director Mrs. Feldman also recognized Robert J. Haynes, president of the Massachusetts AFL-CIO, of the courses Medical Interviewing and At events in May surrounding ™ cancer center advisory council which has made a pledge to raise $5 million through the annual Walk to Cure Cancer held Clinical Problem Solving, and The implementation of the Leave A Legacy each Labor Day, raising funds to construct and outfit the UMass Cancer Center that will Physician, Patient and Society. As a board program, donors learned of the critical Within 30 days of the groundbreaking for the new research laboratory building in be housed on two floors of the research laboratory building and be designated as the member of the Medical School’s Robert role nonprofit groups play in the community. December 1999, an advisory board of 12 members was established, with President Robert Massachusetts AFL-CIO Cancer Research Center upon its completion. Wood Johnson Generalist Physician Charitable bequests through a will or J. Haynes of the Mass. AFL-CIO as its chairman. The Massachusetts AFL-CIO Cancer trust aid the mission of the UMass Research Advisory Board advises Chancellor Aaron Lazare and the director of the UMass Chancellor and Dean Aaron Lazare remarked: “Our donors’ major support for the cutting- Initiative, she collaborated to create a Memorial Foundation, the fund-raising Cancer Center on policy matters concerning cancer research at UMMS and on the edge work done by UMass Medical School investigators will have a direct and immediate new curriculum that helped establish advocate for the research and educational operations of the center. impact on our mission of curing disease and alleviating suffering through research.” John UMMS as a national leader in primary programs at UMMS and the quality L. Sullivan, MD, director of the UMMS Office of Research, described the work to be done care medical education. The UMass Memorial Foundation thanks community and UMMS members of the advisory clinical care UMass Memorial Health Care in that regard by such eminent scientists as Robert W. Finberg, MD, the Richard M. Haidack board for their commitment: UMass Medical School has established provides the region. Donors learned that Professor of Medicine; C. Robert Matthews, PhD, chair of the Department of Biochemistry the Sarah L. Stone, MD, Professorship in by making “planned gifts,” they can & Molecular Pharmacology; Edward I. Ginns, MD, PhD, director of the Irving S. and Betty Brudnick Robert Haynes, Chairman, of Medford Cathy Maniero of Shrewsbury Medical Education to honor Dr. Stone and continue to help foundations and agencies Neuropsychiatric Research Institute; and Steven M. Reppert, MD, the Higgins Family John “Jack” Blais of Framingham Dottie Manning of Marlborough to establish an endowed professorship make a difference in their community. Professor of Neuroscience. Sullivan also praised the over 175 UMMS researchers who have for the advancement of medical education. Senator Harriette Chandler of Worcester Anna Ling Pierce of Princeton succeeded in attracting total research funding to the institution of more than $100 million The UMass Memorial Foundation plans Gene DeFeudis of Northborough Kenneth Rock, MD, of Chestnut Hill Contributions may be sent to the UMMS ™ annually, and who have spearheaded a 22 percent increase in NIH funding over FY ’99. additional Leave A Legacy educational Robert Finberg, MD, of Wayland John Sullivan, MD, of West Boylston Office of Development, Four Biotech, programs. Call the foundation at For information about contributing to the Campaign for Research, Richard Kronish of Newton David West of Worcester Suite 315, 377 Plantation Street, (508) 856-5520 or (508) 334-8055 for contact Campaign Director Pat Bartram at (508) 856-6515. Worcester, Massachusetts 01605. information on dates and times.

26 Vitae spring - summer 2001 spring - summer 2001 Vitae 27 Campaign for Research Chairwoman Nancy Feldman and Chancellor (DeFeudises, continued) Lazare at the Campaign for Research Gala. Funds raised will help construct the research laboratory building, where the Mass. AFL-CIO Their major leadership gift to the Campaign for Research will significantly influence the Cancer Research Center will be housed. future of cancer investigations at UMMS, the institution that grew out of the playing fields of Mr. DeFeudis’ youth. With their generous contribution, the DeFeudises bring their financial support, their dedication to their community and their determination to finding walk to cure cancer a cure for cancer. “This horrible disease of cancer touches so many families, so many ummf initiates continues to aim high ™ lives, and we feel fortunate to be able to offer our support,” said Mrs. DeFeudis. Her leave a legacy Motivation. It springs from many sources husband added: “It is vital to us that a cure is found for this dread disease. We have very What percentage of Americans have and drives the success of the Walk to Cure Gala Emcees Peter Mehegan strong feelings for this community and want to give back.” created a will or trust that leaves Cancer, now in its third year. This Labor Day, of WCVB Channel 5 and bequests to the charitable causes they September 3, some 8,000 motivated walkers Lisa Ling of ABC daytime television support? Though an estimated 70 percent are expected to raise an unprecedented $750,000 for the Massachusetts AFL-CIO Cancer of households nationwide contribute to Research Center, to be housed on two floors of the new research laboratory building. Sarah Stone, MD charity each year, just under six percent At last year’s walk, for example, members of the UMMS School Fiscal Department were our time to lead of them grant a charitable bequest inspired to create Walk to Cure Cancer buttons that staff sold for $1 each. Proud of their through planned giving. This small Amidst the lights, music and celebratory handshakes of friends and colleagues, the Gala fund-raising accomplishment, “Team Fiscal” is challenging departments from both the percentage of bequests is mirrored by for the Campaign for Research served to honor the exceptional growth of the UMass Medical Medical School and UMass Memorial Health Care to participate in 2001. According to walk the relatively few dollars bequeathed— School basic and clinical research enterprise, the leaders and scientists that laid forth the organizers, if half of all employees walked, 5,000 pairs of feet would be traveling around less than eight percent of total gift vision that has hastened its growth, and the donors whose unselfish desire to bring an the banks of Lake Quinsigamond—and into the hearts of cancer victims and their families. end to disease will help put it in its proper place—the new research laboratory building. amounts nationwide. Each year, the number of businesses that have sent teams to the walk has increased. From In an effort to educate current and The Campaign for Research, designed to accelerate the growth of the biomedical research small operations, like Paul’s Center Bakery in Millbury, to Fortune 500 corporations like potential donors about the advantages enterprise through the recruitment of 100 new research faculty and the construction and professorship EMC, front and center on the world economic stage, the incentive to help is easily tapped. outfitting of the Medical School’s research building, moved into its public phase on May 5 honors the memory of charitable giving through bequests, Their enthusiasm is shared by the researchers and clinicians whose programs of with the Gala Celebration at Worcester’s Centrum Centre. of gifted faculty the UMass Memorial Foundation has member become a member of Leave A Legacy™, investigation and treatment will be supported in part by funds raised at the walk. Until May, campaign efforts had focused on securing the leadership gifts that are critical Robert Finberg, MD, the Richard M. Haidack Professor and Chair of Medicine, researches Sarah L. Stone, MD, 44, professor of a community-based program that to achieving the campaign’s $38 million goal. With the May kick-off, the public at large was the connection between the mechanisms of infectious disease and the causes of cancer, medicine at UMass Medical School and advocates charitable giving through a invited to participate in the campaign. and walks with cancer survivors and their families and UMass Cancer Center patients, a general internist at UMass Memorial will or from an estate. The nationwide investigators and staff. All are encouraged by the commitment of the Massachusetts Emcees Peter Mehegan of Channel 5’s “Chronicle,” and father of School of Medicine Health Care, died at home in Natick, Mass. program is a cooperative effort of a AFL-CIO, which, under the motivating force of President Robert J. Haynes, pledged to graduate Kathryn Mehegan, MD, and Lisa Ling, popular daytime talk show co-host and on February 5, 2001, of ovarian cancer. variety of nonprofit groups, including niece of Anna Ling Pierce, founder of Ali & Dad’s Army, introduced speakers and honored educational and health care institutions, raise $5 million through the annual walk. Dr. Stone joined the UMMS faculty in guests to the approximately 300 attendees. “The incredible generosity of our donors social service and cultural organizations Members of unions within the AFL-CIO, such as Mailhandlers Local 301, rise to the 1986 and had a distinguished career as ™ ensures the ultimate success of the Campaign for Research,” said Campaign Chair Nancy and churches. The Leave a Legacy Haynes challenge in increasing numbers each year. Mary Ellen Winkelman, a UMMS a leader in medical education and clinical Edman Feldman. “I am pleased to report that $22 million has been raised over the past program was initiated in Central mailhandler who helps organize teams for the walk, finds that so many of her “brothers care. She served as the director of the 22 months—58 percent of our goal. It is all of you who have made this possible.” Mrs. Massachusetts through the work of and sisters are touched by cancer in some way that it has opened their eyes to this Division of Primary Care and General Feldman acknowledged leadership donors Sarah M. Adams, Gene and Mary DeFeudis, a committee of representatives from cause.” Winkelman, a breast cancer survivor, believes she “puts a face” to the disease, Medicine in the Department of Medicine Barbara and Nathan Greenberg, the late Milton P. and Alice C. Higgins, Dr. and Mrs. Arthur local foundations, including the UMMF, encouraging participation in the walk. On Labor Day 2001, the numbers will back that up. and as associate chair of the Department M. Pappas, the H. Arthur Smith Charitable Foundation and Jack and Shelley Blais, who colleges and universities, civic of Medicine. Dr. Stone was director of the For more information about the 2001 Walk to Cure Cancer, contact Cathy LaRocca, that evening made a surprise announcement that they were contributing an additional organizations and service agencies, Center for Community Faculty event manager, at (508) 856-1634. $2 million to the Campaign, bringing their gift to $5 million. joined by professional financial advisors. Development, and creator and director Mrs. Feldman also recognized Robert J. Haynes, president of the Massachusetts AFL-CIO, of the courses Medical Interviewing and At events in May surrounding ™ cancer center advisory council which has made a pledge to raise $5 million through the annual Walk to Cure Cancer held Clinical Problem Solving, and The implementation of the Leave A Legacy each Labor Day, raising funds to construct and outfit the UMass Cancer Center that will Physician, Patient and Society. As a board program, donors learned of the critical Within 30 days of the groundbreaking for the new research laboratory building in be housed on two floors of the research laboratory building and be designated as the member of the Medical School’s Robert role nonprofit groups play in the community. December 1999, an advisory board of 12 members was established, with President Robert Massachusetts AFL-CIO Cancer Research Center upon its completion. Wood Johnson Generalist Physician Charitable bequests through a will or J. Haynes of the Mass. AFL-CIO as its chairman. The Massachusetts AFL-CIO Cancer trust aid the mission of the UMass Research Advisory Board advises Chancellor Aaron Lazare and the director of the UMass Chancellor and Dean Aaron Lazare remarked: “Our donors’ major support for the cutting- Initiative, she collaborated to create a Memorial Foundation, the fund-raising Cancer Center on policy matters concerning cancer research at UMMS and on the edge work done by UMass Medical School investigators will have a direct and immediate new curriculum that helped establish advocate for the research and educational operations of the center. impact on our mission of curing disease and alleviating suffering through research.” John UMMS as a national leader in primary programs at UMMS and the quality L. Sullivan, MD, director of the UMMS Office of Research, described the work to be done care medical education. The UMass Memorial Foundation thanks community and UMMS members of the advisory clinical care UMass Memorial Health Care in that regard by such eminent scientists as Robert W. Finberg, MD, the Richard M. Haidack board for their commitment: UMass Medical School has established provides the region. Donors learned that Professor of Medicine; C. Robert Matthews, PhD, chair of the Department of Biochemistry the Sarah L. Stone, MD, Professorship in by making “planned gifts,” they can & Molecular Pharmacology; Edward I. Ginns, MD, PhD, director of the Irving S. and Betty Brudnick Robert Haynes, Chairman, of Medford Cathy Maniero of Shrewsbury Medical Education to honor Dr. Stone and continue to help foundations and agencies Neuropsychiatric Research Institute; and Steven M. Reppert, MD, the Higgins Family John “Jack” Blais of Framingham Dottie Manning of Marlborough to establish an endowed professorship make a difference in their community. Professor of Neuroscience. Sullivan also praised the over 175 UMMS researchers who have for the advancement of medical education. Senator Harriette Chandler of Worcester Anna Ling Pierce of Princeton succeeded in attracting total research funding to the institution of more than $100 million The UMass Memorial Foundation plans Gene DeFeudis of Northborough Kenneth Rock, MD, of Chestnut Hill Contributions may be sent to the UMMS ™ annually, and who have spearheaded a 22 percent increase in NIH funding over FY ’99. additional Leave A Legacy educational Robert Finberg, MD, of Wayland John Sullivan, MD, of West Boylston Office of Development, Four Biotech, programs. Call the foundation at For information about contributing to the Campaign for Research, Richard Kronish of Newton David West of Worcester Suite 315, 377 Plantation Street, (508) 856-5520 or (508) 334-8055 for contact Campaign Director Pat Bartram at (508) 856-6515. Worcester, Massachusetts 01605. information on dates and times.

26 Vitae spring - summer 2001 spring - summer 2001 Vitae 27 The Last Word:

As we acknowledge the 10th year of Aaron Lazare's tenure as chancellor/dean we look back on the many milestones that have defined the past decade. A period of tremendous achievement, the 1990s were marked at UMMS by great strides in research, significant academic progress and expansive change in the management of our clinical system.

Vit e: the magazine of the University of Massachusetts Medical School, one of five campuses in the UMass system. 1991 The Office of Commercial Ventures and The Program in Gene Function and Expression a The magazine is distributed twice yearly to members and friends of the UMMS community. Published by the Intellectual Property is established to is established to focus on the molecular Aaron Lazare, MD, becomes Office of Public Affairs & Publications, it is paid for out of non-state funds. chancellor/dean. assist in the transfer of technology from and genetic basis of human disease. the lab to the marketplace. The Department of Psychiatry is 2000 awarded a $1.6 million grant to evaluate 1996

of Distinction UMMS ranks 40th among medical the effectiveness of early school-based UMMS and Smith + Nephew Endoscopy schools nationwide in attracting National intervention for kindergarteners with ADHD. of Andover announce a multimillion-dollar Institutes of Health funding. agreement to establish a research center. 1992 The $12 million Irving S. and Betty Chancellor and Dean Aaron Lazare, MD The five-campus Center for Adoption Brudnick Neuropsychiatric Research The Robert Wood Johnson Foundation Vice Chancellor, University Relations Albert Sherman grants UMMS funds to develop a plan Research is established. Institute opens. A Decade to increase the number of generalist The Association of American Medical UMMS and Advanced BioSciences Associate Vice Chancellor, University Relations Mark L. Shelton physicians educated at the Medical Colleges ranks UMMS fourth nationally Laboratories, Inc. are among four and Managing Editor School. The Generalist Physician Initiative and first in New England in the percentage public/industry partners awarded nearly Director of Constituent Relations Lanny Hilgar award qualifies UMMS to compete for of graduates entering primary care. $14 million from the National Institute of a six-year, $2.5 million award, which it Allergy and Infectious Diseases to Editor Andrea L. Badrigian received in 1994. 1997 develop an HIV vaccine. The Department of Psychiatry and the The New England Newborn Screening UMMS merges with the Eunice Kennedy Writers Lynn C. Borella Worcester Area Community Mental Health Program, which provides health Shriver Center to strengthen research Mary Beth Dziewietin Center agree to an affiliation to enhance screening for over three million infants into mental retardation and human Sandra L. Gray the delivery of comprehensive mental throughout New England, joins UMMS. development. Roxanne Jones health services to Worcester-area residents. The internationally renowned Worcester The Program in Molecular Medicine Design Monderer Design Foundation for Biomedical Research 1993 celebrates its 10th anniversary. merges with UMMS, bringing 16 scientists Printing Springfield Printing Corporation The Massachusetts Department of and $5.5 million in research funding. Five endowed chairs and professorships Mental Health selects the Department are established at UMMS, bringing the Photography Arthur Carvalho The Massachusetts Biologic Laboratories of Psychiatry as one of only two Research total named endowments to 22. Richard Clark join UMMS to become the only publicly Centers of Excellence nationwide. Steve Gilbert operated, FDA-licensed vaccine 2001 Chuck Kidd The Office of Science Education is manufacturing facility in the country. established to create and coordinate For the sixth straight year, UMMS Christopher Navin an array of programs and activities to 1998 is ranked among the nation’s 10 best Marvin Richmond medical schools in primary care Larry Stein promote science in the region’s classrooms. Memorial Health Care merges with the education by U.S.News & World Report, UMMS Biomedical Media UMass Clinical System, creating the largest 1994 coming in at fourth. health care system in Central Massachusetts. The National Library of Medicine UMMS is granted a $10 million award Readers are invited to comment on the contents of the magazine, from the National Institutes of Health to UMMS becomes one of only three designates the Lamar Soutter Library via letters to the editor. take part in the nation’s first-ever, multi- schools nationwide to participate in the as the New England Regional Medical Please address correspondence to: center Women's Health Initiative. Macy Initiative in Health Communication, Library in the National Network of designed to enhance physician Libraries of Medicine. Editor, Vit e The Graduate School of Nursing founds communication skills. a its Collaborative PhD Nursing Program UMMS experiences a 22 percent increase Office of Public Affairs & Publications with UMass Amherst. The Medical School is designated a federal in National Institutes of Health funding UMass Medical School AIDS research center, one of 12 nationwide. over the prior year, attracting total 55 Lake Avenue North 1995 research funding of more than $100 Worcester, MA 01655 1999 The Meyers Primary Care Institute is million annually. UMMS invests seven faculty members www.umassmed.edu established as a research and educational The research laboratory building opens into named professorships, bringing the partnership between UMMS and the in August. When fully occupied, it will total named endowments to 17. Fallon Foundation. house close to 1,000 scientists and staff. The Medical School celebrates its 25th The first Walk to Cure Cancer, a anniversary. collaboration of UMMS, UMass Memorial, the Mass. AFL-CIO and Our Danny Cancer A new Medical School curriculum is Fund, is held, raising $300,000. unveiled, promoting collaborative teaching among clinical and basic Plans are announced to construct a 10- research departments. floor, 360,000-square-foot research laboratory building on campus that will

house current and recruited researchers. The University of Massachusetts Medical School is firmly committed to its policy of equal opportunity through affirmative action and takes active measures against acts of discrimination, harassment and intolerance.

28 Vitae spring - summer 2001 The Last Word:

28 Vitae spring - summer 2001 Non-Profit Org. U.S. Postage paid Worcester, MA Permit No. 176

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