An Emergent Ebola Virus Nucleoprotein Variant Influences Virion
bioRxiv preprint doi: https://doi.org/10.1101/454314; this version posted October 29, 2018. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. 1 An emergent Ebola virus nucleoprotein variant influences virion 2 budding, oligomerization, transcription and replication 3 Aaron E Lin1,2,3,11, William E Diehl4,11, Yingyun Cai5, Courtney Finch5, Chidiebere Akusobi6, 4 Robert N Kirchdoerfer7, Laura Bollinger5, Stephen F Schaffner2,3, Elizabeth A Brown2,3, Erica 5 Ollmann Saphire7,8, Kristian G Andersen7,9, Jens H Kuhn5,12, Jeremy Luban4,12, Pardis C 6 Sabeti1,2,3,10,12 7 8 1Harvard Program in Virology, Harvard Medical School, Boston, MA 02115, USA. 2FAS Center 9 for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, 10 Cambridge, MA 02138, USA. 3Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. 11 4Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 12 01605, USA. 5Integrated Research Facility at Fort Detrick, National Institute of Allergy and 13 Infectious Diseases, National Institutes of Health, Frederick, MD 21702. 6Department of 14 Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 15 02120, USA. 7Department of Immunology and Microbial Sciences, The Scripps Research 16 Institute, La Jolla, CA 92037, USA. 8The Skaggs Institute for Chemical Biology, The Scripps 17 Research Institute, La Jolla, CA 92037, USA. 9Scripps Translational Science Institute, La Jolla, 18 CA 92037, USA.
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