DOCSLIB.ORG

Seven Deadly Medical Hypotheses Stem Cells' Rough Ride Seven Deadly Medical Hypotheses Stem Cells' Rough Ride Questioning IV

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Seven Deadly Medical Hypotheses Stem Cells' Rough Ride Seven Deadly Medical Hypotheses Stem Cells' Rough Ride Questioning IV SI Mar April 2011_SI JF 10 V1 1/21/11 9:46 AM Page 1 Heaven’s Stenographer | Magic or Miracle? | Time Travel | 12 New CSI Fellows Vol. 35 No. 2 | March/April 2011 THE MAGAZINE FOR SCIENCE & REASON Seven Questioning Deadly IV Nutrient Medical Therapy Hypotheses Stem Cells' Strange Rough Ride Problems in the Wegman Report Published by The Committee for Skeptical Inquiry SI Mar Apr 11 (PL) _SI new design masters 1/21/11 10:59 AM Page 2 AT THE CEN TERFOR IN QUIRY /TRANSNATIONAL www.csicop.org Paul Kurtz, Founder Joe Nickell, Senior Research Fellow Richard Schroeder, Chairman Massimo Polidoro, Research Fellow Ronald A. Lindsay, President and CEO Benjamin Radford, Research Fellow Bar ry Karr, Ex ec u tive Di rect or Richard Wiseman, Research Fellow James E. Al cock*, psy chol o gist, York Univ., Tor on to Sus an Haack, Coop er Sen ior Schol ar in Arts and Irm gard Oe pen, pro fes sor of med i cine (re tired), Mar cia An gell, MD, former ed i tor-in-chief, Sci en ces, professor of phi los o phy and professor Mar burg, Ger ma ny New Eng land Jour nal of Med i cine of Law, Univ. of Mi ami Lor en Pan kratz, psy chol o gist, Or e gon Health Kimball Atwood IV, MD, physician, author, Harriet Hall, MD, family physician, investigator, Sci en ces Univ. Newton, MA Puyallup, WA Robert L. Park,professor of physics, Univ. of Maryland Steph en Bar rett, MD, psy chi a trist, au thor, con sum er C.E.M. Han sel, psy chol o gist, Univ. of Wales Jay M. Pasachoff, Field Memorial Professor of ad vo cate, Al len town, PA David J. Helfand, professor of astronomy, Astronomy and director of the Hopkins Willem Betz,MD, professor of medicine, Univ. of Brussels Columbia Univ. Observatory, Williams College Ir ving Bie der man, psy chol o gist, Univ. of Doug las R. Hof stad ter, pro fes sor of hu man John Pau los, math e ma ti cian, Tem ple Univ. South ern CA un der stand ing and cog ni tive sci ence, In di ana Univ. Massimo Pigliucci, professor of philosophy, Sus an Black more, Vis it ing Lec tur er, Univ. of the West Ger ald Hol ton, Mal linc krodt Pro fes sor of Phys ics and City Univ. of New York–Lehman College of Eng land, Bris tol pro fes sor of his to ry of sci ence, Har vard Univ. Stev en Pink er, cog ni tive sci en tist, Harvard Univ. Hen ri Broch, phys i cist, Univ. of Nice, France Ray Hy man*, psy chol o gist, Univ. of Or e gon Philip Plait, astronomer, lecturer, and writer Jan Har old Brun vand, folk lor ist, pro fes sor emer i tus Le on Jar off, sci en ces ed i tor emer i tus, Time Mas si mo Pol id oro, sci ence writer, au thor, ex ec u tive of Eng lish, Univ. of Utah Stuart D. Jordan, NASA astrophysicist emeritus, di rect or of CI CAP, It a ly Mar io Bunge, phi los o pher, McGill Univ., Montreal science advisor to Center for Inquiry Office of James “The Amazing” Randi, magician, CSICOP Robert T. Carroll, emeritus professor of philosophy, Public Policy, Washington, D.C. founding member; founder, James Randi Sacramento City College, writer Ser gei Ka pit za, former ed i tor, Rus sian edi tion, Educational Foundation Sean B. Carroll, molecular geneticist, vice president Sci en tif ic Amer i can Mil ton Ro sen berg, psy chol o gist, Univ. of Chic a go for science education, Howard Hughes Medical In- Law rence M. Krauss, foundation professor, School Wal la ce Sam pson, MD, clin i cal pro fes sor of med i cine, stitute, Madison, WI of Earth and Space Exploration and Physics Dept., Stan ford Univ., ed i tor, Sci en tif ic Re view of John R. Cole, an thro pol o gist, ed i tor, Na tion al director, Origins Initiative, Arizona State Univ. Al ter na tive Med i cine Cen ter for Sci ence Ed u ca tion Harry Kroto, professor of chemistry and Am ar deo Sar ma*, chairman, GWUP, Ger ma ny K.C. Cole, science writer, author, professor, biochemistry, Florida State Univ.; Nobel laureate Ev ry Schatz man, former pres i dent, Univ. of Southern California’s Annenberg Ed win C. Krupp, as tron o mer, di rect or, French Phys ics As so ci a tion School of Journalism Grif fith Ob ser va to ry, Los Angeles, CA Eu ge nie C. Scott*, phys i cal an thro pol o gist, ex ec u tive Fred er ick Crews, lit er ary and cul tur al crit ic, pro fes sor Paul Kurtz, professor emeritus of philosophy, di rect or, Na tion al Cen ter for Sci ence Ed u ca tion emer i tus of Eng lish, Univ. of CA, Berke ley SUNY at Buffalo Rob ert Sheaf fer, sci ence writer Rich ard Dawk ins, zo ol o gist, Ox ford Univ. Law rence Kusche, sci ence writer El ie A. Shne our, bi o chem ist, au thor, president and Ge of frey Dean, tech ni cal ed i tor, Perth, Aus tral ia Le on Le der man, emer i tus di rect or, Fer mi lab; research director, Bi os ys tems Re search In sti tute, Cor nel is de Ja ger, pro fes sor of as tro phys ics, No bel lau re ate in phys ics La Jol la, CA Univ. of Utrecht, The Neth er lands Scott O. Lil i en feld*, psy chol o gist, Emory Univ., Seth Shostak, senior astronomer, SETI Institute, Dan i el C. Den nett, Univ. pro fes sor and Aus tin B. Atlanta, GA Mountain View, CA Fletch er Pro fes sor of Phi los o phy, di rect or of Lin Zix in, former ed i tor, Sci ence and Dick Smith,film pro duc er, pub lish er, Ter rey Hills, Cen ter for Cog ni tive Stud ies at Tufts Uni v. Tech nol o gy Dai ly (Chi na) N.S.W., Aus tral ia Ann Druyan, writer and producer, and CEO, Je re Lipps, Mu se um of Pa le on tol o gy, Univ. of CA, Rob ert Stein er, ma gi cian, au thor, El Cer ri to, CA Cosmos Studios, Ithaca, NY Berke ley Vic tor J. Sten ger, emer i tus pro fes sor of phys ics Ken neth Fed er, pro fes sor of an thro pol o gy, Eliz a beth Loft us, pro fes sor of psy chol o gy, and as tron o my, Univ. of Ha waii; ad junct pro fes sor Cen tral Con nec ti cut State Univ. Univ. of CA, Ir vine of phi los o phy, Univ. of CO Barbara Forrest, professor of philosophy, Da vid Marks, psy chol o gist, City Univ., Lon don Jill Cor nell Tar ter,as tron o mer, SE TI In sti tute, SE Louisiana Univ. Mar io Men dez-Acos ta, jour nal ist and sci ence writer, Moun tain View, CA An drew Fra knoi, as tron o mer, Foot hill Col lege, Mex i co City Car ol Tav ris,psy chol o gist and au thor, Los Ange les, CA Los Al tos Hills, CA Kenneth R. Miller, professor of biology, Da vid E. Thom as*, phys i cist and math e ma ti cian, Kend rick Fra zi er*, sci ence writer, ed i tor, Brown Univ. Per al ta, NM SKEP TI CAL IN QUIR ER Marv in Min sky, pro fes sor of me dia arts and sci en ces, Steph en Toul min, pro fes sor of phi los o phy, Christopher C. French, professor, department M.I.T. Univ. of South ern CA of psychology, and head of the Anomalistic Da vid Mor ri son, space sci en tist, NA SA Ames Re search Neil de Gras se Ty son, as tro phys i cist and di rect or, Psychology Research Unit, Goldsmiths Cen ter Hay den Plan e tar i um, New York City College, Univ. of London Rich ard A. Mul ler, pro fes sor of phys ics, Univ. of CA, Ma ri lyn vos Sa vant, Pa rade mag a zine Yv es Gal i fret, executive secretary, Berke ley con trib ut ing ed i tor l’Union Rationaliste Joe Nick ell, sen ior re search fel low, CSI Stev en Wein berg, pro fes sor of phys ics and as tron o my, Luigi Garlaschelli, chemist, Università di Pavia Jan Willem Nienhuys, mathematician, Waalre, Univ. of Tex as at Aus tin; No bel lau re ate (Italy), research fellow of CICAP, The Netherlands E.O. Wil son, uni ver si ty pro fes sor emer i tus, the Italian skeptics group Lee Nis bet, phi los o pher, Med aille Col lege Har vard Univ. Maryanne Garry, professor, School of Psychology, Steven Novella, MD, assistant professor Rich ard Wis e man, psy chol o gist, Uni ver si ty Victoria Univ. of Wellington, New Zealand of neurology, Yale Univ. School of Medicine of Hert ford shire, England Mur ray Gell-Mann, pro fes sor of phys ics, San ta Fe Bill Nye, sci ence ed u ca tor and tel e vi sion host, Benjamin Wolozin*, professor, department of In sti tute; No bel lau re ate Nye Labs pharmacology, Boston Univ.
Load more

Recommended publications
  • Values, Justifications, and Perspectives Connected to the Anti-Vaccination Movement Gigi Garzio [email protected]
    View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Sound Ideas University of Puget Sound Sound Ideas Summer Research Summer 2018 Values, Justifications, and Perspectives Connected to the Anti-Vaccination Movement Gigi Garzio [email protected] Follow this and additional works at: https://soundideas.pugetsound.edu/summer_research Part of the Anthropology Commons, and the Medicine and Health Commons Recommended Citation Garzio, Gigi, "Values, Justifications, and Perspectives Connected to the Anti-Vaccination Movement" (2018). Summer Research. 309. https://soundideas.pugetsound.edu/summer_research/309 This Article is brought to you for free and open access by Sound Ideas. It has been accepted for inclusion in Summer Research by an authorized administrator of Sound Ideas. For more information, please contact [email protected]. Introduction Throughout the 18th and 19th centuries, when the first smallpox outbreak began and the first vaccine was introduced, there has been vaccine skepticism (Offit, 2015). Smallpox outbreaks, and the fatalities that come with it, continued to spread around the world despite the development of the vaccine. However, between the 1940s and the early 1970s, anti-vaccine sentiment declined due to “three trends: a boom in vaccine science, discovery, and manufacture; public awareness of widespread outbreaks of infectious diseases (measles, mumps, rubella, pertussis, polio, and others) and the desire to protect children from these highly prevalent ills; and a baby boom, accompanied by increasing levels of education and wealth” (Poland et al, 2011). These factors led to general public acceptance of vaccines, which resulted in significant decreases in disease outbreaks. However, with less visible outbreaks of disease and more vaccines being added to the childhood vaccination schedule, the presence of the anti-vaccination movement returned in the 1970s (Wolfe, 2002).
    [Show full text]
  • Vaccines and Autism: What You Should Know | Vaccine Education
    Q A Vaccines and Autism: What you should know Volume& 1 Summer 2008 Some parents of children with autism are concerned that vaccines are the cause. Their concerns center on three areas: the combination measles-mumps-rubella (MMR) vaccine; thimerosal, a mercury-containing preservative previously contained in several vaccines; and the notion that babies receive too many vaccines too soon. Q. What are the symptoms of autism? Q. Does the MMR vaccine cause autism? A. Symptoms of autism, which typically appear during the A. No. In 1998, a British researcher named Andrew Wakefi eld fi rst few years of life, include diffi culties with behavior, social raised the notion that the MMR vaccine might cause autism. skills and communication. Specifi cally, children with autism In the medical journal The Lancet, he reported the stories of may have diffi culty interacting socially with parents, siblings eight children who developed autism and intestinal problems and other people; have diffi culty with transitions and need soon after receiving the MMR vaccine. To determine whether routine; engage in repetitive behaviors such as hand fl apping Wakefi eld’s suspicion was correct, researchers performed or rocking; display a preoccupation with activities or toys; a series of studies comparing hundreds of thousands of and suffer a heightened sensitivity to noise and sounds. children who had received the MMR vaccine with hundreds Autism spectrum disorders vary in the type and severity of of thousands who had never received the vaccine. They found the symptoms they cause, so two children with autism may that the risk of autism was the same in both groups.
    [Show full text]
  • Science Reporting Syllabus: Covering the Environment, Technology and Medicine
    1 Science reporting syllabus: Covering the environment, technology and medicine Science reporting is in a moment of extreme transition: Popular science writing is experiencing a renaissance at precisely the moment that traditional media outlets are jettisoning specialized reporters. This creates tremendous opportunity and tremendous challenges. This course makes sure students are prepared to meet those challenges. Course objective This course is designed to acquaint reporters with all aspects of science reporting and writing. It will train participants to view new breakthroughs and discoveries with skepticism and will give students a working knowledge of many of the main areas of science coverage, including the environment, artificial intelligence, and human interaction with technology. There will be lessons on social media, online writing, news and feature writing, and writing long-form narratives. Learning objectives The syllabus is designed to strengthen students’ core competencies in several areas: Determining what sources and outlets can be trusted to discuss controversial or unproven claims. Learning which questions will elicit meaningful responses. Understanding that choosing not to cover a story can be just as important an editorial decision as deciding how to cover it. Evaluating what type of form a journalist is most comfortable with and seeking out ways to work in that form. Course design This course will focus on developing toolkits for evaluating science stories in addition to learning about some specific issues or controversies. It is designed as a workshop course for between 10 and 15 students. An integral part of the course is analyzing and critiquing other students’ work. Readings Required books Deborah Blum, Mary Knudson and Robin Marantz Henig, editors, A Field Guide for Science Writers, 2005.
    [Show full text]
  • NIH FOIA Log - FY 2017
    NIH FOIA Log - FY 2017 Date Request Id Organization Name City State Records Requested Received 45612 LSU Health - Shreveport Shreveport Louisiana Copies of 3 NIDDK grants. 10/3/2016 Records relating to the use of the investigational drug Fostriecin in a human clinical trial sponsored by the NCI's Cancer Therapy Evaluation 45614 Individual Lakeway Texas Program. 10/3/2016 Site visit reports for UTMB (3/1/15- present); Battelle-Ohio (10/1/15- present); and Alpha Genesis-SC 45615 SAEN Milford Ohio (4/1/14-present). 10/3/2016 A copy of NCI grant 1R43CA135915- 45616 UCLA School of Engineering Los Angeles California 01. 10/4/2016 Washington University School of A copy of NIAID grant 45617 Medicine St. Louis Missouri K22AI052407. 10/4/2016 Washington University School of A copy of NHLBI grant 45618 Medicine St. Louis Missouri R01HL081398. 10/4/2016 Grant application and summary Washington University School of statement for NIDDK grant 45619 Medicine St. Louis Missouri K01DK077878. 10/4/2016 Data pertaining to all NIH purchases of the Victor model plate reader (model Victor 1, 2, 3 and Victor X) 45620 IMGEN Technologies Alexandria Virginia from Perkin Elmer from 1999-2012. 10/3/2016 Copy of NEI grant R21EY026438- 45621 Tufts Medical Center Brookline Massachusetts 01. 10/5/2016 A copy of all emails to and from two NIH employees from May 25, 2016 to June 25, 2016 regarding the NTP 45622 Individual Greenbelt Maryland radiofrequency study. 10/5/2016 Date Request Id Organization Name City State Records Requested Received Copies of the RCDC Thesaurus from 45623 Catenion Berlin Other 2010-2014.
    [Show full text]
  • Morgellons: an Exercise in Medical Validation Introduction
    Harry Quinn Schone Morgellons: an exercise in medical validation Introduction Morgellons may or may not be a modern affliction, but the circumstances in which it exists are distinctly specific to the 21st century.1 The existing literature is both sparse and voluminous. Medical journal work is lacking, whilst patient­written material stretches all over the internet.2 Almost totally absent is an academic effort which tries to document what has happened from a social constructivist position, taking account of both accredited literature and otherwise. In the following piece I hope to go some way towards filling this gap, and so I will now briefly outline my point of view. I do not believe it is necessary to engage in complex and often circular debates about aetiology. Remove this dangerous temptation and what is left is the processes: who is made to feel how and by what means; what makes a ‘disease’, what is ‘medical authority’ and how does it exercise said authority? These are the questions I hope to answer. Neutrality is impossible, but hopefully by aiming towards it I can achieve something close to meaningful analysis as a byproduct of such efforts. To this end I have attempted to regard both academic and non­academic sources as valuable. ‘Sticking to the literature’ in this case would I believe prove myopic and do a disservice to the heterogeneity of the actors involved. In short, I am not concerned so much with the symptoms and the various causal debates, but rather with the way that Morgellons illustrates power structures between patients and the medical community.
    [Show full text]
  • Hearing Before the Committee on Government Reform
    DOCUMENT RESUME ED 466 915 EC 309 063 TITLE Autism: Present Challenges, Future Needs--Why the Increased Rates? Hearing before the Committee on Government Reform. House of Representatives, One Hundred Sixth Congress, Second Session (April 6,2000). INSTITUTION Congress of the U.S., Washington, DC. House Committee on Government Reform. REPORT NO House-Hrg-106-180 PUB DATE 2001-00-00 NOTE 483p. AVAILABLE FROM Government Printing Office, Superintendent of Documents, Congressional Sales Office, Washington, DC 20402-9328. Tel: 202-512-1800. For full text: http://www.house.gov/reform. PUB TYPE Legal/Legislative/Regulatory Materials (090) EDRS PRICE EDRS Price MF02/PC20 Plus Postage. DESCRIPTORS *Autism; *Child Health; Children; *Disease Control; *Etiology; Family Problems; Hearings; *Immunization Programs; Incidence; Influences; Parent Attitudes; *Preventive Medicine; Research Needs; Symptoms (Individual Disorders) IDENTIFIERS Congress 106th; Vaccination ABSTRACT This document contains the proceedings of a hearing on April 6, 2000, before the U.S. House of Representatives Committee on Government Reform. The hearing addressed the increasing rate of children diagnosed with autism, possible links between autism and childhood vaccinations, and future needs of these children. After opening statements by congressmen on the Committee, the statements and testimony of Kenneth Curtis, James Smythe, Shelley Reynolds, Jeana Smith, Scott Bono, and Dr. Wayne M. Danker, all parents of children with autism, are included. Their statements discuss symptoms of autism, vaccination concerns, family problems, financial concerns, and how parents can be helped. The statements and testimony of the second panel are then provided, including that of Andrew Wakefield, John O'Leary, Vijendra K. Singh, Coleen A. Boyle, Ben Schwartz, Paul A.
    [Show full text]
  • World's Oldest Man Dies in NYC at Age 111 9 June 2014
    World's oldest man dies in NYC at age 111 9 June 2014 The world's oldest man, a retired chemist and The world's oldest person is a woman, 116-year-old parapsychologist, has died in New York City at the Misao Okawa of Japan. age of 111. © 2014 The Associated Press. All rights reserved. Alexander Imich died Sunday at his home in Manhattan, according to his niece, Karen Bogen of Providence, Rhode Island. She said she visited him a day earlier with her sister and several of his close friends. Imich attributed his longevity to good genetics, proper nutrition and exercise and the fact that he and his wife, who died in 1986, did not have children, said Bogen. Michael Mannion, a longtime friend, said Imich's "enormous curiosity and ability to turn even great adversity into something positive were important factors in his long life. These qualities were evident even in his last weeks and days of life." At the age of 93, Imich enrolled for three years at the IM School of Healing Arts, a school that offers programs in self-awareness and hands-on healing, "because he wanted to learn more about love," said Mannion. Imich detailed the work of a Polish medium known as Matylda S. in his book "Incredible Tales of the Paranormal," which was published in 1995 when he was 92. Imich was born in 1903 in a town in Poland that was then part of Russia. He and his wife fled after the Nazis invaded in 1939. They moved to the United States in 1951.
    [Show full text]
  • Calendar No. 238
    Calendar No. 238 110TH CONGRESS " ! REPORT 1st Session SENATE 110–107 DEPARTMENTS OF LABOR, HEALTH AND HUMAN SERVICES, AND EDUCATION, AND RELATED AGENCIES APPROPRIATION BILL, 2008 R E P O R T OF THE COMMITTEE ON APPROPRIATIONS U.S. SENATE ON S. 1710 JUNE 27, 2007.—Ordered to be printed Departments of Labor, Health and Human Services, and Education, and Related Agencies Appropriation Bill, 2008 (S. 1710) Calendar No. 238 110TH CONGRESS REPORT " ! 1st Session SENATE 110–107 DEPARTMENTS OF LABOR, HEALTH AND HUMAN SERV- ICES, AND EDUCATION, AND RELATED AGENCIES APPRO- PRIATION BILL, 2008 JUNE 27, 2007.—Ordered to be printed Mr. HARKIN, from the Committee on Appropriations, submitted the following REPORT [To accompany S. 1710] The Committee on Appropriations reports the bill (S. 1710) mak- ing appropriations for Departments of Labor, Health and Human Services, and Education and related agencies for the fiscal year ending September 30, 2008, and for other purposes, reports favor- ably thereon and recommends that the bill do pass. Amount of budget authority Total of bill as reported to the Senate ............. $605,536,474,000 Amount of 2007 appropriations ........................ 545,857,321,000 Amount of 2008 budget estimate ...................... 596,378,249,000 Bill as recommended to Senate compared to— 2007 appropriations .................................... ∂59,679,153,000 2008 budget estimate ................................. ∂9,158,225,000 36–285 PDF CONTENTS Page Summary of Budget Estimates and Committee Recommendations ...................
    [Show full text]
  • Healing with Magnets by Gary Null, Ph.D
    Healing With Magnets By Gary Null, Ph.D. With Vicki Riba Koestler Biomagnetic therapy is not a new to everyone. Many veterinarians have been aware of biomagnetic benefits for years, and use magnets to heal fractures quickly, thereby saving the lives of racehorses and other animals. Doctors treating professional athletes commonly recommend magnets to speed up recovery from painful injuries. And other physicians in a variety of specialties, including dermatologists, internists, pediatricians, and surgeons, are seeing excellent results as well That magnetic healing is nothing new can be seen by looking at early records of scientifically advanced civilizations, which tell us that magnetic forces have long been prized for their restorative properties. Ancient Greece discovered the very first natural magnet in the form of the lodestone, said Hippocrates, the father of medicine, noted its healing power. The Egyptians, too, described the divine powers of the magnet in their writings, and Cleopatra frequently adorned herself with magnetic jewelry to preserve her youthfulness. Chinese manuscripts dating back thousands of years describe the Eastern belief that the life force, termed qi , is generated by the earth’s magnetic field. Today, many believe that certain places on earth, such as Lourdes, France, and Sedona, Arizona, owe their healing powers to naturally high levels of this qi , or biomagnetic energy. Finally, no one claims that magnetic therapy is going to work for everyone. However, ample clinical and personal evidence suggests that people experience a beneficial effect. One is led to ponder whether when Hippocrates wrote, “The natural force within each of us is that greatest healer of all,” he did not have magnetic energy in mind.
    [Show full text]
  • BOCEAN™ TEST* Manual *Transcutaneous–Electro-Supplement Therapy
    BOCEAN™ TEST* Manual *Transcutaneous–Electro-Supplement Therapy Making HOCL (Hypochlorous Acid) supplement IN the body Page 1 of 42 Table of Contents INTRODUCTION ............................................................................................................................................................... 5 WHAT DOES TRANSCUTANEOUS-ELECTROTHERAPY DO? ................................................................................................. 6 SUPPLIES NECESSARY FOR THE COURSE ........................................................................................................................... 7 • BASIC PORTABLE UNIT: ................................................................................................................................... 7 o 9 V batteries................................................................................................................................................... 7 o AA OR AAA BATTERY HOLDERS: https://www.ebay.com/sch/i.html?_from=R40&_nkw=AAA+Batteries+Case+wire+lead&_sacat=0&LH_TitleDesc=0& LH_PrefLoc=1&_sop=15 ........................................................................................................................................... 7 • FIXED UNIT: ....................................................................................................................................................... 7 o 6-Volt lantern battery or a 9-volt -buy at a local store ............................................................................. 7 o OR a USB
    [Show full text]
  • Humankind 2.0: the Technologies of the Future 6. Biotech
    Humankind 2.0: The Technologies of the Future 6. Biotech Piero Scaruffi, 2017 See http://www.scaruffi.com/singular/human20.html for the full text of this discussion A brief History of Biotech 1953: Discovery of the structure of the DNA 2 A brief History of Biotech 1969: Jon Beckwith isolates a gene 1973: Stanley Cohen and Herbert Boyer create the first recombinant DNA organism 1974: Waclaw Szybalski coins the term "synthetic biology” 1975: Paul Berg organizes the Asilomar conference on recombinant DNA 3 A brief History of Biotech 1976: Genentech is founded 1977: Fred Sanger invents a method for rapid DNA sequencing and publishes the first full DNA genome of a living being Janet Rossant creates a chimera combining two mice species 1980: Genentech’s IPO, first biotech IPO 4 A brief History of Biotech 1982: The first biotech drug, Humulin, is approved for sale (Eli Lilly + Genentech) 1983: Kary Mullis invents the polymerase chain reaction (PCR) for copying genes 1986: Leroy Hood invents a way to automate gene sequencing 1986: Mario Capecchi performs gene editing on a mouse 1990: William French Anderson’s gene therapy 1990: First baby born via PGD (Alan Handyside’s lab) 5 A brief History of Biotech 1994: FlavrSavr Tomato 1994: Maria Jasin’s homing endonucleases for genome editing 1996: Srinivasan Chandrasegaran’s ZFN method for genome editing 1996: Ian Wilmut clones the first mammal, the sheep Dolly 1997: Dennis Lo detects fetal DNA in the mother’s blood 2000: George Davey Smith introduces Mendelian randomization 6 A brief History of Biotech
    [Show full text]
  • RNA-Based Reprogramming
    RESEARCH HIGHLIGHTS STEM CELLS RNA-based reprogramming RNA molecules can both induce pluripo- RNA-based technique instead of viral tech- development, began producing myotubes. In tency and direct differentiation. niques for much of its induced pluripotent fact, Rossi expects that techniques using RNA The ability to make person-specific pluri- stem cell production. for differentiation will probably be adopted potent stem cells opens up many possibilities Getting the technique to work required more quickly than using RNA for reprogram- for research tools and perhaps even therapies. a lot of trial and error, says Rossi. His first ming. “I think people will have an easier time But most reprogramming techniques alter cells’ attempts to reprogram cells with RNA failed in differentiation because it’s often one factor genomes, making cells less predictable and more because cells responded as if they had been rather than several,” he says. prone to cancer-like growth. Methods to repro- infected by a virus, committing apoptosis or Making the modified RNA itself is easy, gram cells without changing their genomes launching other antiviral defenses. Swapping says Rossi, but researchers will need to exist but are inefficient and labor-intensive; out two nucleosides with similar analogs mit- spend some time tinkering to find the best most also rely on DNA and so still carry the igated the response and allowed the research- conditions for their systems. Every aspect risk of unintended genetic alterations. ers to reprogram cultured human cells by of culture conditions affects how cells are A reprogramming technique recently applying daily doses of RNAs coding for four transfected with RNA, he says.
    [Show full text]