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Supplementary Table 1

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Supplementary Table 1 Wild type F1/F10 (villus/crypt) Probe set Gene symbol Gene name Fold change p value defensin related 1450709_at Defcr5 cryptdin 5 0.009 < 1e-07 cDNA sequence 1429378_x_at AY761184 AY761184 0.038 < 1e-07 intelectin 1 (galactofuranos 1418165_at Itln1 e binding) 0.043 1.00E-07 defensin related sequence cryptdin peptide 1418550_x_at Defcr-rs1 (paneth cells) 0.044 < 1e-07 1439426_x_at Lyz2 lysozyme 2 0.059 < 1e-07 potassium intermediate/sm all conductance calcium- activated channel, subfamily N, 1435945_a_at Kcnn4 member 4 0.061 1.00E-07 cysteine and glycine-rich 1420731_a_at Csrp2 protein 2 0.065 1.20E-06 CDC28 protein 1416698_a_at Cks1b kinase 1b 0.065 < 1e-07 transferrin 1452661_at Tfrc receptor 0.066 2.00E-07 solute carrier family 12, 1417622_at Slc12a2 member 2 0.066 3.00E-07 fatty acid binding protein 6, ileal 1450682_at Fabp6 (gastrotropin) 0.067 < 1e-07 1415849_s_at Stmn1 stathmin 1 0.069 < 1e-07 deleted in malignant brain 1418287_a_at Dmbt1 tumors 1 0.070 3.00E-07 RIKEN cDNA 9130208D14 1440922_at 9130208D14Rik gene 0.071 1.26E-05 cell division cycle 20 homolog (S. 1439377_x_at Cdc20 cerevisiae) 0.072 7.00E-07 heat shock 1427126_at Hspa1b protein 1B 0.080 3.00E-07 defensin related 1450631_x_at Defcr6 cryptdin 6 0.081 < 1e-07 carbonic 1418094_s_at Car4 anhydrase 4 0.082 6.00E-07 cysteine rich 1416039_x_at Cyr61 protein 61 0.082 1.00E-07 1436996_x_at Lyz1 lysozyme 1 0.084 < 1e-07 aldehyde dehydrogenase 1 family, 1451260_at Aldh1b1 member B1 0.090 5.00E-07 nucleolar protein 1455035_s_at Nol5a 5A 0.093 1.40E-06 cysteine rich 1438133_a_at Cyr61 protein 61 0.096 1.00E-07 heat shock 1452388_at Hspa1a protein 1A 0.105 2.00E-07 topoisomerase 1454694_a_at Top2a (DNA) II alpha 0.106 1.00E-07 heat shock 1427127_x_at Hspa1b protein 1B 0.107 5.00E-07 heat shock protein 1 1426351_at Hspd1 (chaperonin) 0.108 1.00E-07 minichromosom e maintenance deficient 5, cell division cycle 46 1436808_x_at Mcm5 (S. cerevisiae) 0.108 < 1e-07 protease, 1437671_x_at Prss23 serine, 23 0.111 6.00E-07 ATPase family, AAA domain 1438178_x_at Atad3a containing 3A 0.111 2.00E-07 inner centromere 1439436_x_at Incenp protein 0.114 < 1e-07 tubulin, alpha 1423846_x_at Tuba1b 1B 0.121 < 1e-07 angiogenin, ribonuclease A family, member 1440832_at Ang4 4 0.122 1.80E-06 CDC28 protein kinase regulatory 1417457_at Cks2 subunit 2 0.123 1.00E-07 microsomal glutathione S- 1415897_a_at Mgst1 transferase 1 0.124 4.00E-07 complement component 1, q subcomponent 1455821_x_at C1qbp binding protein 0.125 3.00E-07 solute carrier family 7 (cationic amino acid transporter, y+ system), 1454991_at Slc7a1 member 1 0.127 1.00E-07 non-SMC condensin I complex, 1436707_x_at Ncaph subunit H 0.127 9.00E-07 proteolipid 1453572_a_at Plp2 protein 2 0.128 8.00E-07 H2A histone family, member 1416746_at H2afx X 0.130 7.30E-06 small nucleolar RNA, C/D box 1433674_a_at Snord22 22 0.130 < 1e-07 heat shock protein 1 1450668_s_at Hspe1 (chaperonin 10) 0.130 7.00E-07 ATPase family, AAA domain 1456541_x_at Atad3a containing 3A 0.131 6.00E-07 cystic fibrosis transmembrane conductance regulator 1420579_s_at Cftr homolog 0.135 2.20E-06 heat shock 105kDa/110kDa 1425993_a_at Hsph1 protein 1 0.135 1.00E-07 kinesin family 1437716_x_at Kif22 member 22 0.139 3.00E-07 DNA segment, Chr 17, human 1417822_at D17H6S56E-5 D6S56E 5 0.140 4.70E-06 cell division cycle associated 1436847_s_at Cdca8 8 0.146 2.03E-05 small nucleolar RNA host gene (non-protein 1439399_a_at Snhg1 coding) 1 0.146 1.00E-07 ribosomal 1416453_x_at Rps12 protein S12 0.146 1.20E-06 heat shock 1452318_a_at Hspa1b protein 1B 0.147 2.00E-07 protein tyrosine phosphatase- like (proline instead of catalytic arginine), 1457434_s_at Ptpla member a 0.149 2.30E-06 uridine-cytidine 1439740_s_at Uck2 kinase 2 0.152 6.97E-05 carbamoyl- phosphate 1455540_at Cps1 synthetase 1 0.152 1.01E-05 1452614_at Bcl2l15 BCLl2-like 15 0.153 2.00E-07 1438938_x_at Phb2 prohibitin 2 0.154 2.80E-06 ribosomal 1451077_at Rpl5 protein L5 0.155 1.09E-05 RIKEN cDNA 1300001I01 1428106_at 1300001I01Rik gene 0.155 2.70E-06 1442710_at NA NA 0.155 5.00E-07 RIKEN cDNA 2810417H13 1419153_at 2810417H13Rik gene 0.156 1.40E-06 proliferation- 1420142_s_at Pa2g4 associated 2G4 0.156 6.80E-06 cyclin- dependent 1455287_at Cdk6 kinase 6 0.158 3.90E-06 solute carrier organic anion transporter family, member 1433933_s_at Slco2b1 2b1 0.159 2.26E-05 alanyl (membrane) 1421424_a_at Anpep aminopeptidase 0.159 0.0007021 nucleolar protein family A, 1416606_s_at Nola2 member 2 0.160 1.70E-06 translocase of inner mitochondrial membrane 8 homolog a1 1416345_at Timm8a1 (yeast) 0.160 2.23E-05 high mobility group nucleosomal binding domain 1455897_x_at Hmgn1 1 0.161 2.00E-07 brain expressed 1448595_a_at Bex1 gene 1 0.161 3.70E-05 predicted gene, OTTMUSG0000 OTTMUSG0000 1437610_x_at 0016200 0016200 0.162 4.00E-07 high mobility 1437313_x_at Hmgb2 group box 2 0.162 2.00E-07 1425952_a_at Gcg glucagon 0.164 1.09E-05 FAST kinase 1426741_a_at Fastkd2 domains 2 0.164 5.00E-07 solute carrier family 12, 1448780_at Slc12a2 member 2 0.166 9.98E-05 complement component 1, q subcomponent 1448274_at C1qbp binding protein 0.166 5.60E-06 predicted gene, OTTMUSG0000 OTTMUSG0000 1455319_x_at 0022847 0022847 0.167 1.40E-06 CDC28 protein kinase regulatory 1417458_s_at Cks2 subunit 2 0.168 7.00E-07 MAD2 (mitotic arrest deficient, homolog)-like 1 1422460_at Mad2l1 (yeast) 0.169 1.59E-05 L1 cell adhesion 1450435_at L1cam molecule 0.169 1.40E-06 ribosomal 1433928_a_at Rpl13a protein L13a 0.170 5.00E-07 transglutaminas e 2, C 1455900_x_at Tgm2 polypeptide 0.171 2.00E-06 PYD and CARD domain 1417346_at Pycard containing 0.171 6.10E-06 ribosomal 1439374_x_at Rps10 protein S10 0.173 8.63E-05 heat shock protein 90kDa alpha (cytosolic), class 1416364_at Hsp90ab1 B member 1 0.174 1.80E-06 TRM1 tRNA methyltransferas e 1 homolog (S. 1436494_x_at Trmt1 cerevisiae) 0.174 3.50E-06 ornithine aminotransferas 1416452_at Oat e 0.174 1.41E-05 interferon induced transmembrane 1417460_at Ifitm2 protein 2 0.174 2.36E-05 ribosomal 1416807_at Rpl36a protein L36a 0.175 4.30E-06 chaperonin containing Tcp1, subunit 3 1459987_s_at Cct3 (gamma) 0.175 1.30E-06 bleomycin 1438961_s_at Blmh hydrolase 0.176 9.00E-07 1419513_a_at Ect2 ect2 oncogene 0.176 1.44E-05 eukaryotic translation elongation factor 1448252_a_at Eef1b2 1 beta 2 0.178 5.00E-07 small nucleolar RNA, C/D box 1433675_at Snord22 22 0.178 1.40E-06 1443649_at NA NA 0.179 9.90E-06 ribosomal 1438986_x_at Rps17 protein S17 0.179 1.10E-06 interleukin enhancer 1417948_s_at Ilf2 binding factor 2 0.179 2.14E-05 minichromosom e maintenance deficient 7 (S. 1438320_s_at Mcm7 cerevisiae) 0.179 1.40E-06 S- adenosylmethio nine 1448484_at Amd1 decarboxylase 1 0.179 3.00E-07 similar to calponin 3, 1436836_x_at LOC100047856 acidic 0.180 1.10E-06 cell division cycle associated 1416802_a_at Cdca5 5 0.181 5.64E-05 ribosomal 1455950_x_at Rpl35 protein L35 0.184 4.00E-07 muscleblind-like 1434678_at Mbnl3 3 (Drosophila) 0.184 3.20E-06 inosine 5@#$%&- phosphate dehydrogenase 1415851_a_at Impdh2 2 0.186 1.70E-06 1434280_at NA NA 0.186 7.00E-07 1422489_at Gcs1 glucosidase 1 0.186 8.70E-06 ribosomal 1416603_at Rpl22 protein L22 0.187 1.20E-06 small nucleolar RNA host gene (non-protein 1436506_a_at Snhg6 coding) 6 0.188 1.30E-06 RIKEN cDNA 3110001A13 1416893_at 3110001A13Rik gene 0.188 0.0001044 phosphatidyleth anolamine 1438649_x_at Pebp1 binding protein 1 0.188 1.30E-06 ribosomal 1434231_x_at Rpl35 protein L35 0.189 8.00E-07 ribosomal 1437510_x_at Rps17 protein S17 0.190 1.30E-06 5- aminoimidazole- 4-carboxamide ribonucleotide formyltransferas e/IMP 1428506_at Atic cyclohydrolase 0.191 9.60E-06 FGF receptor activating 1424615_at Frag1 protein 1 0.191 4.30E-06 protein tyrosine phosphatase- like (proline instead of catalytic arginine), 1456315_a_at Ptpla member a 0.192 0.0001153 ribosomal 1438794_x_at Rps13 protein S13 0.192 1.50E-06 1450920_at Ccnb2 cyclin B2 0.193 2.55E-05 1447046_at NA NA 0.194 7.10E-06 asparagine- linked glycosylation 8 homolog (yeast, alpha-1,3- glucosyltransfer 1455887_at Alg8 ase) 0.194 5.62E-05 methionine adenosyltransfer 1438630_x_at Mat2a ase II, alpha 0.194 4.00E-07 GDP-mannose 4, 6- 1434158_at Gmds dehydratase 0.195 2.80E-06 cysteine rich 1457823_at Cyr61 protein 61 0.196 0.0004907 phenylalanyl- tRNA synthetase, beta 1435103_x_at Farsb subunit 0.196 3.10E-06 ribosomal 1436840_x_at Rpl35 protein L35 0.196 8.00E-07 phosphohistidin 1427903_at Phpt1 e phosphatase 1 0.197 0.0001114 ribosomal 1448245_at Rpsa protein SA 0.197 1.40E-06 predicted gene, 1433510_x_at 100043718 100043718 0.197 1.70E-06 E2F transcription 1455790_at E2f2 factor 2 0.198 6.30E-06 MYB binding protein (P160) 1423431_a_at Mybbp1a 1a 0.199 5.40E-06 RIKEN cDNA 2410006H16 1447936_at 2410006H16Rik gene 0.200 7.00E-07 tripartite motif- 1415869_a_at Trim28 containing 28 0.200 6.90E-06 1452426_x_at NA NA 0.200 2.60E-06 guanine nucleotide binding protein- 1433656_a_at Gnl3 like 3 (nucleolar) 0.201 7.00E-07 transmembrane 1428465_at Tmem147 protein 147 0.201 9.93E-05 1426946_at Ipo5 importin 5 0.202 1.10E-05 regulator of chromosome 1426897_at Rcc2 condensation 2 0.202 0.0001447 cold shock domain protein 1435800_a_at Csda A 0.202 1.84E-05 predicted gene, 1438940_x_at 100040836 100040836 0.202 5.70E-06 CCAAT/enhanc er binding protein (C/EBP), 1418901_at Cebpb beta 0.203 1.52E-05 ribosomal 1455001_x_at Rpl13a protein L13a 0.203 1.11E-05 SH2 domain 1453377_at Sh2d4a containing 4A 0.205 6.60E-06 RIKEN cDNA 1110038B12 1441081_a_at 1110038B12Rik gene 0.205 9.00E-07 AFFX- TransRecMur/X57 transferrin 349_3_at Tfrc receptor 0.206 8.80E-06 inosine 5@#$%&- phosphate
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