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Supplemental data 1. Differentially expressed genes between MIN-Os and normal (prelactating and virgin combined)

A. Genes down-regulated in MIN-Os probe set Gene Title Gene Symbo GO biological process 97519_at secreted phosphoprotein 1 Spp1 103257_at RIKEN cDNA C730036B01 gene C730036B01Rik 92994_at lactalbumin, alpha Lalba Carbohydrate 102121_f_at keratin complex 1, acidic, gene 19 Krt1-19 99994_at cell death-inducing DNA fragmentation factor, alpha subunit-lCidea metabolism 92550_at keratin complex 1, acidic, gene 19 Krt1-19 94507_at fatty acid Coenzyme A ligase, long chain 2 Facl2 Lipid and Organic acid metabolism 100567_at fatty acid binding 4, adipocyte Fabp4 93308_s_at pyruvate carboxylase Pcx Lipid and 98575_at fatty acid synthase Fasn Lipid and Organic acid metabolism 100924_at GATA binding protein 3 Gata3 160306_at thyroid hormone responsive SPOT14 homolog (Rattus) Thrsp 92851_at ceruloplasmin Cp 97316_at RIKEN cDNA 1300002P22 gene 1300002P22RLipid and Organic acid metabolism 97826_at RIKEN cDNA A430096B05 gene A430096B05Rik 96348_at RIKEN cDNA 0610039C21 gene 0610039C21Rik 103422_at CD1d1 antigen Cd1d1 97926_s_at peroxisome proliferator activated receptor gamma Pparg 101082_at malic , supernatant Mod1 Lipid, Organic acid and Carbohydrate metabo 160083_at lipoprotein lipase Lpl 103665_at ELOVL family member 6, elongation of long chain fatty acids Elovl6 Lipid and Organic acid metabolism 103087_at sulfotransferase family 1A, phenol-preferring, member 1 Sult1a1 Lipid metabolism 96803_at glucan (1,4-alpha-), branching enzyme 1 Gbe1 Carbohydrate metabolism 95611_at lipoprotein lipase Lpl Lipid metabolism 97990_at myosin heavy chain 11, smooth muscle Myh11 103617_at decay accelerating factor 1 Daf1 94057_g_at stearoyl-Coenzyme A desaturase 1 Scd1 Organic acid metabolism 161753_f_at -3- dehydrogenase 1 (soluble) Gpd1 Lipid and Carbohydrate metabolism 92592_at glycerol-3-phosphate dehydrogenase 1 (soluble) Gpd1 Lipid and Carbohydrate metabolism 160108_at nuclear protein 1 Nupr1 104516_at claudin 5 Cldn5 92880_at milk fat globule-EGF factor 8 protein Mfge8 98892_at lipin 1 Lpin1 Lipid metabolism 104477_at Mus musculus transcribed sequences --- 93497_at complement component 3 C3 160207_at ATP citrate lyase Acly Lipid and Organic acid metabolism 102049_at , isoenzyme 4 Pdk4 Organic acid metabolism 94056_at stearoyl-Coenzyme A desaturase 1 Scd1 Lipid and Organic acid metabolism 93332_at CD36 antigen Cd36 98102_at pyruvate dehydrogenase E1 alpha 1 Pdha1 Carbohydrate metabolism 104126_at cleavage stimulation factor, 3' pre-RNA subunit 2, tau Cstf2t 92581_at acetyl-Coenzyme A dehydrogenase, medium chain Acadm Lipid and Organic acid metabolism 160989_r_at RIKEN cDNA B430320C24 gene B430320C24Rik 96746_at dihydrolipoamide S-acetyltransferase (E2 component of pyru Dlat Organic acid metabolism 160547_s_at thioredoxin interacting protein Txnip 94806_at pyruvate dehydrogenase (lipoamide) beta Pdhb Carbohydrate metabolism

B. Genes up-regulated in MIN-Os probe set Gene Title Gene Symbo GO biological process 94628_r_at androgen binding protein, alpha Abpa 97487_at (or cysteine) proteinase inhibitor, clade E, member 2 Serpine2 103905_at RIKEN cDNA 2310047E01 gene 2310047E01Rik 92402_at ------162475_f_at peptidoglycan recognition protein Pglyrp 101883_s_at X-linked lymphocyte-regulated 3b Xlr3b 95082_at insulin-like growth factor binding protein 3 Igfbp3 92644_s_at myeloblastosis oncogene Myb Cell proliferation 99578_at topoisomerase (DNA) II alpha Top2a Cell proliferation 92459_at chemokine (C-C motif) ligand 8 Ccl8 92665_f_at X-linked lymphocyte-regulated complex Xlr 101521_at baculoviral IAP repeat-containing 5 Birc5 104099_at peptidoglycan recognition protein Pglyrp 93615_at pre B-cell leukemia transcription factor 3 Pbx3 100019_at chondroitin sulfate 2 Cspg2 93479_at RIKEN cDNA A930031D07 gene A930031D07Rik 93250_r_at high mobility group box 2 Hmgb2 97527_at CDC28 protein kinase regulatory subunit 2 Cks2 Cell proliferation 97825_at p53 apoptosis effector related to Pmp22 Perp-pending 100144_at nucleolin Ncl 98524_f_at ------104303_i_at RIKEN cDNA 1500004O14 gene 1500004O14Rik 92810_at pyruvate dehydrogenase kinase, isoenzyme 3 Pdk3 160159_at cyclin B1 Ccnb1 Cell proliferation 95753_at RIKEN cDNA A730011O11 gene A730011O11RCell proliferation 95927_f_at RIKEN cDNA 2610201A13 gene 2610201A13Rik 100348_at ------161172_f_at RIKEN cDNA A730011O11 gene A730011O11RCell proliferation 97238_at transforming, acidic coiled-coil containing protein 3 Tacc3 Cell proliferation 99149_at RIKEN cDNA 2310035M22 gene 2310035M22Rik 96772_at DNA primase, p49 subunit Prim1 Cell proliferation 100955_at RIKEN cDNA 2700084L22 gene 2700084L22RNucleic acid metabolism 92790_at karyopherin (importin) alpha 2 Kpna2 metabolism, Transport 97824_at DNA segment, Chr 11, ERATO Doi 175, expressed D11Ertd175e Nucleic acid metabolism 102001_at M2 Rrm2 Cell proliferation 97411_at ect2 oncogene Ect2 Cell proliferation 104097_at budding uninhibited by benzimidazoles 1 homolog (S. cerevisBub1 Cell proliferation, Nucleic acid metabolism 93285_at dual specificity phosphatase 6 Dusp6 Nucleic acid metabolism 94247_at RIKEN cDNA 5730453H04 gene 5730453H04Rik 100128_at cell division cycle 2 homolog A (S. pombe) Cdc2a Cell proliferation, Nucleic acid metabolism 93592_at apolipoprotein D Apod Transport 94232_at cyclin D1 Ccnd1 Cell proliferation 96696_at heterogeneous nuclear ribonucleoproteins methyltransferaseHrmt1l2 92639_at serine/threonine kinase 6 Stk6 Cell proliferation, Nucleic acid metabolism 100116_at RIKEN cDNA 2810417H13 gene 2810417H13Rik 94294_at cyclin B2 Ccnb2 Cell proliferation 98077_at small nuclear ribonucleoprotein D3 Snrpd3 96025_g_at S-adenosylhomocysteine hydrolase Ahcy 96024_at S-adenosylhomocysteine hydrolase Ahcy 160501_at kinesin family member 20A Kif20a Transport 92569_f_at nucleolar protein 5 Nol5 Nucleic acid metabolism, Transport 95083_at insulin-like growth factor binding protein 3 Igfbp3 93999_at small nuclear ribonucleoprotein polypeptide G Snrpg 100577_at small nuclear ribonucleoprotein D1 Snrpd1 93261_at legumain Lgmn Nucleic acid metabolism 101017_at cyclin-dependent kinase 4 Cdk4 Cell proliferation 97497_at Notch gene homolog 1 (Drosophila) Notch1 Cell proliferation, Nucleic acid metabolism 92829_at heat shock protein 1 (chaperonin 10) Hspe1 Nucleic acid metabolism 102821_s_at RAS-like, family 2, locus 9 Rasl2-9 Transport 101065_at proliferating cell nuclear antigen Pcna Cell proliferation 161968_f_at chemokine (C-C motif) receptor 5 Ccr5 104174_at ectonucleotide pyrophosphatase/phosphodiesterase 1 Enpp1 103444_at RIKEN cDNA E130315B21 gene E130315B21Rik 101589_at high mobility group nucleosomal binding domain 2 Hmgn2 97907_at LSM7 homolog, U6 small nuclear RNA associated (S. cerevisLsm7 97997_at secreted frizzled-related sequence protein 1 Sfrp1 102632_at calmodulin binding protein 1 Calmbp1 160890_at lamin B receptor Lbr 160973_at RIKEN cDNA C330027C09 gene C330027C09Rik 102934_s_at cell division cycle 25 homolog C (S. cerevisiae) Cdc25c Cell proliferation, Nucleic acid metabolism 160461_f_at RIKEN cDNA 2310057H16 gene 2310057H16RTransport 97200_f_at small nuclear ribonucleoprotein E Snrpe 94805_f_at ------96020_at complement component 1, q subcomponent, beta polypeptid C1qb 161000_i_at RIKEN cDNA 2610201A12 gene 2610201A12Rik 94456_at SET translocation Set Cell proliferation 93277_at heat shock protein 1 (chaperonin) Hspd1 161856_f_at kinesin family member 20A Kif20a Transport 101466_at phosphatidylinositol , class F Pigf Nucleic acid metabolism 160648_at fidgetin-like 1 Fignl1 100983_at prolyl endopeptidase Prep Nucleic acid metabolism 100886_f_at mitochondrial ribosomal protein L45 Mrpl45 160496_s_at minichromosome maintenance deficient 3 (S. cerevisiae) Mcm3 Cell proliferation 101254_at RAN, member RAS oncogene family Ran Cell proliferation, Nucleic acid metabolism, Tr 103418_at replication factor C (activator 1) 4 Rfc4 Cell proliferation 96016_at Mus musculus cDNA clone MGC:67366 IMAGE:5683334, co --- 94494_at phenylalanine-tRNA synthetase-like Farsl Nucleic acid metabolism 93536_at Bcl2-associated X protein Bax 99662_at pericentrin 2 Pcnt2 98562_at complement component 1, q subcomponent, alpha polypeptidC1qa 96168_at kinesin family member 23 Kif23 160069_at geminin Gmnn Cell proliferation 161046_at cytokine receptor-like factor 1 Crlf1 97820_at galactokinase 1 Galk1 100472_at enabled homolog (Drosophila) Enah 97274_at proteasome (prosome, macropain) 26S subunit, non-ATPasePsmd14 fold change P value PL 142 PL 143 V 5169 V 5184 Normal meanSE 5169 MINO -28.21 0.048 8067.99 8524.04 1311.59 2268.91 4930.82 1982.7 137.53 -13.92 0.011 341.31 242.97 630.41 852.67 516.65 140.13 41.65 -12.19 0.046 6589.24 7728.8 1393.78 1633.84 4338.43 1642.98 312.2 -11.81 0.001 1014.27 1053.37 1235.22 1932.44 1308.73 213.81 59.48 -8.44 0.007 1132.85 1294.74 964.78 315.34 926.62 215.06 104.09 -8.06 0.001 1406.66 2012.61 1905.51 2932.24 2063.29 319.48 181.54 -7.92 0.001 3010.51 2169.6 1410.78 2038.46 2157.44 331 269.29 -6.84 0.034 83.76 130.52 224.48 381.04 204.95 65.71 30.49 -6.78 0.048 564.89 666.17 1644.07 2628.15 1373.03 488.33 212.71 -6.68 0.000 6238.91 7372.53 8557.4 10413.32 8139.6 919.25 1327.77 -6.51 0.000 1191.29 828.95 864.63 1290.98 1042.72 119.09 146.44 -6.36 0.000 5136.8 5887.57 6471.37 7147.48 6114.01 482.87 999.07 -6.16 0.026 2545.81 1528.2 600.16 999.08 1418.54 421.74 234.98 -5.83 0.028 307.75 205.97 62.48 129.66 176.48 52.74 28.11 -5.53 0.049 514.21 312.17 1625.29 1573.84 1005.83 347.15 165.8 -4.87 0.027 1857.38 2684.42 4259.17 6899.67 3923.01 1115.27 878.69 -4.84 0.036 298.31 302.64 496.45 971.45 517.25 158.48 105.11 -4.74 0.032 106.17 181.01 196.82 412.18 224.01 65.93 36.67 -4.72 0.016 423.38 860 755.32 1454.66 873.21 214.97 251.93 -4.64 0.000 2669.24 2456.01 1821.76 3054.18 2499.25 264.44 406.92 -4.59 0.022 203.33 1082.09 748.42 1081.48 778.69 206.77 178.25 -4.39 0.027 601.44 428.16 994.63 1541.72 891.43 247.49 158.38 -4.3 0.033 45 98 98.82 196.89 109.68 31.68 21.25 -3.86 0.001 4536.63 4644.12 6370.04 7920.62 5865.81 818.79 1161.26 -3.8 0.014 1160.53 886.59 491.71 483.1 755.65 164.58 188.44 -3.71 0.003 392.06 343.14 182.27 255.78 293.22 46.82 68.59 -3.63 0.001 5932.93 9052.56 9717.81 11572.61 9036.5 1193.46 2465.17 -3.61 0.009 141.07 396.65 361.13 447.97 336.59 67.61 84.21 -3.59 0.007 917.8 2623.17 2060.46 2472.77 2018.09 384.48 526.63 -3.51 0.002 754.56 436.32 645 867.45 675.08 94.8 210.76 -3.36 0.001 296.02 369.11 210.96 340.76 304.37 34.3 68.79 -3.29 0.015 10525.11 10674.39 4819.35 4810.45 7706.62 1671.32 2171.87 -3.25 0.000 485.6 416.65 522 607.85 505.68 43.58 144.67 -3.24 0.020 366.45 336.51 114.93 204.17 255.71 58.71 73.37 -3.23 0.000 4660.82 4306.64 3859.82 4822.96 4419.94 225.73 1122.37 -3.21 0.001 2929.83 3778.68 2381.7 4212 3315.39 417.99 1092.33 -2.96 0.010 253.16 629.83 485.45 355.09 430.4 81.36 123.09 -2.95 0.001 7797.45 10993.04 13556.8 13922.09 11528.2 1475.9 3940.03 -2.93 0.001 258.99 248.96 147.63 274.15 231.98 29.26 70.32 -2.83 0.000 3112.2 3453.48 2645.24 2990.3 3051.56 167.79 1065.01 -2.78 0.004 260.4 199.56 128.34 185.62 193.31 27.61 47.66 -2.78 0.006 457.72 718.86 1028.32 935.39 784.34 128.74 267.61 -2.72 0.000 140.36 139.02 139.89 177.83 149.04 9.93 43.41 -2.59 0.000 822.94 802.46 616.57 685.55 731.44 49.85 251.19 -2.42 0.000 3529.95 3253.16 2989.51 4338.63 3506.47 311.36 1277.23 -2.36 0.000 2080.88 2073.38 1715.28 2049.73 1982.47 92.9 927.2

fold change P value PL 142 PL 143 V 5169 V 5184 Normal meanSE 5169 MINO 14.03 0.042 55.14 51.7 42.73 37.08 45.27 7.47 1202.11 10.47 0.005 56.38 56.86 98.52 84.78 75.91 18.18 407.65 7.88 0.006 83.88 78.1 76.61 89.72 81.89 17.26 726.6 7.2 0.000 287.59 202.35 174.11 205.97 214.74 33.1 1941.33 6.55 0.037 153.68 97.36 45.56 50.96 87.38 28.91 529.14 6.28 0.000 56.7 51.22 45.16 72.1 56.76 9.8 371.16 6.25 0.026 100.13 88.34 192.25 210.22 147.39 32.33 381.66 5.89 0.001 24.61 17.3 38.18 47.54 31.73 7.3 231.21 5.74 0.000 108.96 93.55 50.16 70.63 81.35 14.44 459.47 5.63 0.000 303.49 292.07 331.59 265.38 298.4 25.83 1475.7 5.57 0.000 26.6 24.41 21.62 25.95 24.58 2.28 161.38 5.47 0.003 209 172.84 84.15 94.21 139.48 32.87 785.67 5.38 0.037 322.47 246.69 82.21 74.12 181.69 62.26 904.34 5.25 0.001 60.12 39.56 42.7 69.96 53.02 7.45 334.61 5.11 0.001 141.93 155.92 144.43 151.34 148.74 10.95 484.56 5.1 0.023 77.05 79.51 79.62 58.3 73.21 9.91 374.57 5.01 0.005 30.61 28.36 17.84 30.84 26.7 3.42 156.98 4.83 0.000 137.94 119.93 57.5 80.86 98.88 19.35 531.76 4.65 0.000 352.89 264.44 161.71 201.69 244.41 43.49 964.32 4.33 0.000 816.07 786.09 1231.62 1470.99 1076.94 168.25 5408.82 4.32 0.000 666.94 473.82 139.23 277.6 387.42 118.14 2038.77 4.25 0.000 82.24 65.56 42.5 65.6 63.97 8.76 341.17 4.23 0.000 83.36 66.67 60.89 97.89 77.5 9.32 377.05 4.17 0.000 115.27 98.09 48.35 60.01 79.81 17.07 321.39 4.02 0.000 63.06 60.14 26.36 34.98 46.52 9.66 162.24 4.01 0.001 38.58 35.06 38.32 48.42 40.07 4.27 160.35 3.98 0.018 43.68 45.3 55.36 47.62 47.82 8.48 211.38 3.9 0.000 47.94 40.59 18.19 29.91 34.08 7.17 124.21 3.88 0.000 62.06 40.19 30.72 38.31 42.96 7.19 186.73 3.88 0.000 61.17 61.79 38.55 50.13 52.9 5.85 182.55 3.82 0.001 109.04 88.24 63.87 95.23 89.69 10.48 387.55 3.77 0.000 26.6 23.57 20.07 20.84 22.81 2.5 97.09 3.68 0.003 295.74 204.56 65.03 110.24 168.63 51.88 724.96 3.63 0.003 732.4 634.02 349.84 437.21 537.72 89.55 2276.65 3.62 0.001 146.46 137.42 73.02 78.18 108.16 21.57 463.49 3.54 0.000 85.85 83.65 35.15 51.29 64.23 13.56 258.41 3.53 0.000 76.71 79.11 36.62 44.58 59.13 11.14 208.09 3.53 0.000 138.4 133.36 191.08 326.07 196.72 46.03 648.45 3.52 0.001 144.19 104.37 213.31 364.09 206.6 58.4 804.76 3.51 0.001 382.11 321.93 220.55 231.18 292.89 45.94 1114.12 3.49 0.006 129.64 142.76 455.94 369.74 274.88 84.19 700.27 3.46 0.000 539.58 360.15 236.98 472.99 404.92 69.78 1687.59 3.46 0.000 174.22 118.23 198.76 204.88 171.61 23.8 718.9 3.44 0.000 97.45 88.13 72.53 77.63 84.17 8.64 312.49 3.43 0.003 197.34 154.43 61 90.57 125.5 31.59 446.11 3.42 0.001 358.57 310.36 137.04 184.26 241.62 60.9 861.71 3.39 0.006 108.59 144.06 119.9 171.97 136.41 14.58 543.42 3.35 0.001 612.86 534.65 488.75 509.17 536.72 33.15 2358.46 3.3 0.001 288.34 261.34 205.15 266.2 254.06 22.05 1060.29 3.22 0.001 53.76 50.87 33.5 32.93 43.07 6.25 144.71 3.21 0.003 266.23 166.35 134.36 198.27 191.37 28.56 886.61 3.21 0.014 154.74 167.85 186.38 183.04 173.25 18.79 308.9 3.16 0.005 534.43 396.04 522.1 590.27 510.43 45.57 1704.6 3.11 0.001 151.24 123.97 58.79 155.91 122.47 22.52 434.54 3.1 0.000 186.94 173.06 282.24 306.48 239.16 36.73 718.95 3.09 0.002 295.48 296.58 193.32 232.52 255.64 27.45 753.73 3.08 0.003 369.74 290.23 402.46 593.23 414.05 68.66 1441.11 3.07 0.000 913.25 738.46 892.58 1434.82 994.06 153.26 3114.48 3.02 0.001 1004.46 810.06 589.59 844.04 808.98 91.19 2644.18 2.96 0.001 671 496.08 299.7 482.75 486.67 78.17 1699.1 2.95 0.000 38.74 34.84 41.01 31.92 36.61 2.55 126.74 2.93 0.000 76.3 80.56 69.39 64.81 72 6.36 208.57 2.87 0.000 79.62 61.07 54.36 54.25 62.53 6.85 172.48 2.82 0.000 387.56 306.9 225.15 298.86 304.77 35.28 914.89 2.82 0.001 364.16 270.97 285.05 342.66 315.11 26.47 910.78 2.82 0.002 100.36 76.99 136.05 153.86 116.43 19.53 281.22 2.81 0.000 34.35 34.16 21.15 26.65 29.08 3.67 77.42 2.81 0.000 200.93 158.46 156.63 204.15 180.01 16.64 594.36 2.81 0.000 54.6 48.84 32.34 35.8 42.81 6.13 129.72 2.8 0.000 106.21 99.85 65.65 72.86 86.23 14.43 244.04 2.79 0.000 839.65 624.71 684.2 975.15 780.33 81.36 2340.95 2.79 0.000 868.02 691.83 592.72 709.08 714.66 60.22 2072.21 2.75 0.001 3041.98 2746.65 1526.86 2009.39 2321.04 389.14 6055.48 2.74 0.001 334.04 392.76 565.74 623.8 479.01 70.66 1536.75 2.71 0.000 164.7 158.41 62.33 105.96 122.55 24.46 293.54 2.7 0.001 528.81 491.59 375.34 585.2 494.26 47.18 1404.07 2.69 0.000 1211.57 997.58 1051.85 1825.63 1270.64 196.21 3372.95 2.65 0.001 184.65 157.68 117.02 139.51 150.47 17.64 397.2 2.64 0.001 52.59 47.14 53.23 70.31 56.17 6.31 120.05 2.64 0.000 117.36 128.59 87.53 102.6 108.2 9.93 261.12 2.62 0.001 106.61 105.53 103.73 116.75 108.74 6.09 315.69 2.61 0.001 138.95 123.44 162.8 181.28 152.26 15.47 458.44 2.61 0.000 341.63 314.44 167.68 220.45 260.69 42.26 759.75 2.59 0.000 2522.24 1988.86 1259.18 1776.74 1883.01 269.12 5163.02 2.59 0.000 179.61 189.56 119.7 141.2 156.95 17.29 416.45 2.59 0.000 422.44 362.09 461 427.26 415.26 37.9 1013.75 2.58 0.001 140.66 126.19 103.69 162.57 133.48 12.75 399.4 2.57 0.001 305.99 277.77 222.89 318.04 282.2 25.14 858.81 2.53 0.000 110.46 94.9 96.48 132.82 108.81 9.57 332.31 2.49 0.000 774.02 788.44 1035.21 1145.18 936.06 95.44 2555.48 2.48 0.000 120.34 148.52 120.08 140.7 133.12 9.34 332.64 2.43 0.000 117.9 107.72 85.39 95.14 103.41 9.99 269.39 2.43 0.000 93.84 112.29 85.61 99.76 97.03 9.32 230.38 2.43 0.000 185.33 165.93 142.81 176.86 168.23 10.56 463.73 2.35 0.000 126 118.2 133.34 128.07 125.77 7.57 301.46 2.32 0.000 423.39 342.51 339.89 451.2 389.2 29.04 964.58 5184 MINO 5209 MINO 5261 MINO MINO mean SE 246 204.52 110.93 174.77 31.39 38.95 31.61 36.98 37.13 4.02 642.98 241.51 240.64 355.85 102.19 291.78 42.63 49.19 110.82 60.52 116.45 95.58 123.9 109.79 11.68 517.75 157.94 162.46 256.13 90.66 231.07 234.65 357.22 272.54 29.41 19.04 33.07 36.22 29.95 9.36 203.86 170.03 223.48 202.65 11.8 1285.79 686.86 1665.72 1217.86 223.19 164.6 102.3 230.15 160.1 26.96 1142.42 771.65 939.65 961.48 79.92 246.01 228.06 211.73 230.23 11.02 32.69 24.27 35.74 30.26 3.08 188.84 181.01 191.25 181.74 10.91 887.09 666.98 795.12 806.12 76.11 97.9 94.83 129.14 106.91 8.21 39.16 47.39 65.23 47.21 6.73 209.4 101.51 177.97 185.17 32.42 490.22 598.54 664.56 538.71 57.54 179.73 153.12 167.06 169.6 8.79 219.86 211.7 222.75 203.01 15.58 25.06 22.73 32.3 25.52 2.66 1491.66 1536.85 1931.17 1521.2 163.68 295.7 73.24 239.1 199.04 47.2 110.36 61.13 75.42 78.93 10.95 2604.44 2661.96 2242.78 2489.34 115.05 96 95.31 99.12 93.28 6.8 555.4 562.92 596.43 561.45 22.85 206.27 151.29 200.75 192.46 16.77 105.69 108.07 79.71 90.63 10.51 2357.22 1992.09 2884.49 2339.67 199.84 173.79 153.02 153.04 155.74 17.73 81.18 81.57 81.19 78.86 3.43 1143.72 947.99 2262.29 1367.03 298.41 1116.36 907.55 1015.62 1033.83 49.86 138.36 169.54 145.03 145.3 11.51 4316.5 4017.48 3396.12 3912.73 222.97 79.51 81.75 84.56 79.09 5.68 1061.94 1095.29 1091.02 1078.88 19.09 69.26 78.11 82.68 69.5 8.11 311.56 247.7 304.22 282.39 15.83 60.89 65.18 49.99 54.81 5.75 274.2 290.08 305.55 282.22 16.55 1355.25 1587.77 1591.27 1450.74 83.58 786.59 912.73 730.36 839.57 51.28

5184 MINO 5209 MINO 5261 MINO MINO mean SE 608 43.39 686.34 634.93 237.34 581.22 1109.92 1079.93 794.47 177.11 538.32 321.69 994.27 644.94 142.12 1487.06 1355.99 1405.74 1547.13 136.41 517.6 166.68 1076.3 572.13 186.47 370.79 315.35 371.3 356.73 15.11 527.29 1343.36 1434.71 921.21 272.36 174.56 226.97 114.48 186.75 28.11 436.61 563.65 408.61 466.95 35.46 1177.21 1900.08 2165.5 1679.69 219.69 124.8 93.28 168.92 136.9 17.6 728.23 1102.26 433.61 762.52 139.25 974.33 271.16 1762.02 977.77 304.5 174.66 288.01 316.97 278.35 36.47 712.8 882.01 957.16 759.6 104.48 419.46 99.52 599.28 373.26 102.62 109.17 190.71 78.8 133.71 25.95 485.71 543.61 347.48 477.09 46.8 1284.23 1365.15 931.15 1135.72 112.36 4667.96 4332.85 4262.51 4666.79 274.9 1554.43 1774.95 1326.18 1673.58 158.66 237.11 299.19 209.65 271.85 30.31 305.03 312.99 316.8 327.7 17.64 307.51 411.27 289.28 333.06 29.19 173.66 229.81 181.81 187.22 15.61 130.44 219.5 132.75 160.71 21.4 260.44 57.38 232.93 190.34 45.73 126.81 150.1 129.31 132.98 6.63 141.67 188.35 151.63 166.77 12.89 185.7 245.44 207.49 205.43 15.06 299.43 442.11 240.5 342.32 45.67 79.76 99.37 68.39 85.96 8.01 576.54 788.89 394.37 621.38 89.25 1707.93 2566.93 1249.74 1950.8 297.74 311.05 471.45 322.21 391.71 45.55 227.63 244.68 178.02 227.06 18.97 221.62 225.13 180.26 208.74 10.86 868.81 644.94 618.05 694.99 59.58 778.5 522.01 806.28 727.45 69.15 1036.51 1270 698.2 1029.05 123.91 1238.56 681.82 1222.09 960.39 155.45 1479.17 1288.81 1154.23 1401.33 122.4 575.35 466.2 593.83 594.04 53.45 289.1 342.99 212.56 289.39 28.67 386.36 585.41 307.48 430.96 60.2 842.05 978.44 617.03 825.42 77.93 399.93 641.33 265.74 462.44 83.54 1727.39 1921.04 1196.76 1800.47 244.47 858.55 899.74 535.6 837.98 112.92 135.99 172.12 102.55 138.69 14.93 518.41 525.8 523.5 613.52 91.88 410.5 794.08 706.25 555.3 116.28 1286.9 2332.77 1121.25 1610.84 274.35 284.33 464.2 339.75 380.75 42.1 601.86 884.98 767.25 741.99 62.48 650.39 1101.99 655.69 790.22 108.1 1692.59 861.26 1115.04 1275.06 185.55 3003.71 3546.82 2528.65 3050.13 219.56 2113.05 3164.49 1836.05 2439.38 298.68 1162.46 1643.83 1255.56 1439.92 140.36 100.54 83.79 121.1 108.01 9.95 201.05 256.95 176.68 211.12 17.9 146.36 222.48 177.43 179.26 16.61 724.41 1044.22 752.33 859.12 78.65 762.04 1174.98 709.25 889.61 107.1 250.66 429.19 356.84 328.62 41.67 89.61 85.14 74.95 81.8 4.04 455.51 574.01 402.62 506.07 48.33 120.83 98.21 133.16 120.31 8.09 245.69 276.83 203.03 241.65 17.61 2316.61 2290.28 1741.47 2173.26 150.27 1624.44 2423.32 1844.48 1990.62 175.28 5038.25 6090.79 8318.84 6379.26 688.67 1268.97 1439.22 1004.65 1312.39 119.67 372.21 347.78 314.72 331.81 18.27 1122.73 1735.04 1084.65 1336.32 155.75 3570.55 3673.53 3073.78 3418.95 150.39 404.19 488.37 303.05 398.51 39.35 136.16 191.89 146.08 148.5 15.73 280.85 324.5 276.07 285.52 14.58 294.03 333.19 197.77 285.13 31.05 365.23 466.74 297.96 396.99 41.55 597.69 660.02 707.86 680.85 35.76 4529.85 5664.1 4123.19 4872.49 358.53 351.56 493.03 366.93 406.88 32.47 976.81 1348.31 969.86 1077.26 94.4 334.47 403.49 240.47 344.44 39.26 769.3 790.93 488.05 726.6 83.99 261.58 282.29 224.56 275.1 23.48 2307.32 2155.62 2323.13 2332.54 88.67 308.27 380.71 302.61 330.78 18.74 218.61 261.19 254.87 250.88 12.25 238.68 220.69 255.8 235.81 8.23 367.75 477.06 326.87 408.68 38.04 262.83 277.52 340.91 295.23 17.65 869.18 945.72 838.46 904.5 32.68