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Cell Circuitry || Science Teaches English || The Chicken Genome Is Hot || Magnets in Medicine SEPTEMBER 2002 www.hhmi.org/bulletin Leading Doublea Life It’s a stretch, but doctors who work bench to bedside say they wouldn’t do it any other way. FEATURES 14 On Human Terms 24 The Evolutionary War A small—some say too small—group of Efforts to undermine evolution education have physician-scientists believes the best science evolved into a 21st-century marketing cam- requires patient contact. paign that relies on legal acumen, manipulation By Marlene Cimons of scientific literature and grassroots tactics. 20 Engineering the Cell By Trisha Gura Adam Arkin sees the cell as a mechanical system. He hopes to transform molecular 28 Call of the Wild biology into a kind of cellular engineering Could quirky, new animal models help scien- and in the process, learn how to move cells tists learn how to regenerate human limbs or from sickness to health. avert the debilitating effects of a stroke? By M. Mitchell Waldrop By Kathryn Brown 24 In front of a crowd of 1,500, Ohio’s Board of Education heard testimony on whether students should learn about intelligent design in science class. DEPARTMENTS 2 NOTA BENE 33 PERSPECTIVE ulletin Intelligent Design Is a Cop-Out 4 LETTERS September 2002 || Volume 15 Number 3 NEWS AND NOTES HHMI TRUSTEES PRESIDENT’S LETTER 5 JAMES A. BAKER, III, ESQ. 34 Senior Partner, Baker & Botts A Creative Influence In from the Fields ALEXANDER G. BEARN, M.D. Executive Officer, American Philosophical Society 35 Lost on the Tip of the Tongue Adjunct Professor, The Rockefeller University UP FRONT Professor Emeritus of Medicine, Cornell University Medical College 36 Biology by Numbers FRANK WILLIAM GAY 6 Follow the Songbird Former President and Chief Executive Officer, SUMMA Corporation JAMES H. -
2006 Badgerchemist.Pdf
Est. 1953. NO. 50 2006 Badger Chemist THE NEWSLETTER OF THE UNIVERSITY OF WISCONSIN - MADISON CHEMISTRY DEPARTMENT The Newsletter of THE UNIVERSITY OF WISCONSIN–MADISON C hemistr Y Department CONTENTS From the Chair. 1 Our Awards . 2 New Badger Chemists . 5 Other Notable News. 7 Current Chemistry News. 9 Wisconsin Initiative for Science Literacy . 13 Institute for Chemical Education . 15 Shainfest—Honoring a Researcher, Educator, & Leader. 16 Shainfest Chemistry Symposium. 18 Nanoscale Science and Engineering Center Outreach. 21 Journal of Chemical Education & National Science Digital Library. 23 This ‘n’ That . 25 Chemistry Department Support . 27 Donors to Department Funds . 30 In Memoriam. 33 2006 BADGER CHEMIST Matthew Sanders Editor Designed by the Instructional Media Development Center School of Education, University of Wisconsin–Madison Est. 1953 NO. 50 Linda Endlich Art Direction 2006 Amanda Schmitt & Barb Smith Production Assistance From the Chair March 2007 Dear Badger Chemists, This newsletter, under the exceptional editorship of our Executive Director, Matt Sanders, is a wonderful vehicle for communicating our activities to alumni and friends. This issue of the Badger Chemist highlights our activities of the 2005-06 academic year, and indeed, there were many! Certainly one of the high points of the year was “Shainfest,” a celebration of the career of Professor Irving Shain, former Chemistry Department Chair and Chancellor of the University of Wisconsin. We named our new research wing the “Shain Research Tower” at a ceremony in May 2006, organized by Bassam Shakhashiri and attended by such dignitaries as Governor Jim Doyle, Provost Patrick Farrell and former Dean Phil Certain. The celebration continued with science and outreach presentations, and a banquet. -
Nobel Laureates Endorse Joe Biden
Nobel Laureates endorse Joe Biden 81 American Nobel Laureates in Physics, Chemistry, and Medicine have signed this letter to express their support for former Vice President Joe Biden in the 2020 election for President of the United States. At no time in our nation’s history has there been a greater need for our leaders to appreciate the value of science in formulating public policy. During his long record of public service, Joe Biden has consistently demonstrated his willingness to listen to experts, his understanding of the value of international collaboration in research, and his respect for the contribution that immigrants make to the intellectual life of our country. As American citizens and as scientists, we wholeheartedly endorse Joe Biden for President. Name Category Prize Year Peter Agre Chemistry 2003 Sidney Altman Chemistry 1989 Frances H. Arnold Chemistry 2018 Paul Berg Chemistry 1980 Thomas R. Cech Chemistry 1989 Martin Chalfie Chemistry 2008 Elias James Corey Chemistry 1990 Joachim Frank Chemistry 2017 Walter Gilbert Chemistry 1980 John B. Goodenough Chemistry 2019 Alan Heeger Chemistry 2000 Dudley R. Herschbach Chemistry 1986 Roald Hoffmann Chemistry 1981 Brian K. Kobilka Chemistry 2012 Roger D. Kornberg Chemistry 2006 Robert J. Lefkowitz Chemistry 2012 Roderick MacKinnon Chemistry 2003 Paul L. Modrich Chemistry 2015 William E. Moerner Chemistry 2014 Mario J. Molina Chemistry 1995 Richard R. Schrock Chemistry 2005 K. Barry Sharpless Chemistry 2001 Sir James Fraser Stoddart Chemistry 2016 M. Stanley Whittingham Chemistry 2019 James P. Allison Medicine 2018 Richard Axel Medicine 2004 David Baltimore Medicine 1975 J. Michael Bishop Medicine 1989 Elizabeth H. Blackburn Medicine 2009 Michael S. -
Report to DPR from the Panel Conducting the Peer Review of The
1 May 7, 2011 Administrator Lisa Jackson United States Environmental Protection Agency Ariel Rios Building 1200 Pennsylvania Avenue, N. W. Mail Code: 1101A Washington, DC 20460 Re: Docket ID number EPA-HQ-OPP-2010-0541, Petition to Suspend and Cancel All Registrations for the Soil Fumigant Iodomethane (Methyl Iodide) Dear Administrator Jackson, We are pleased to see that US EPA has decided to reconsider the registration of methyl iodide for its use as a soil fumigant pesticide. We remain concerned about the wisdom of widespread dispersion of methyl iodide into the environment and support the petition to cancel all uses of this chemical as a pesticide. It is one of the more hazardous chemicals used in research labs and in the chemical industry, and it seems counterintuitive that EPA would work on one hand to prevent and document relatively small releases of methyl iodide used in research and chemical manufacturing, while permitting what will likely be millions of pounds to be used annually in agriculture near homes, schools and workplaces. In our letter to EPA of September 24, 2007, (which we sent a copy of to you in February of 2009), we strongly recommended that EPA not register methyl iodide, but if the Agency chose to do so, we recommended that US EPA obtain an external scientific peer review of the risk assessment. While EPA did not commission such a review, the state of California has conducted its own risk assessment and did commission a Scientific Review Committee (SRC) to evaluate US EPA’s and the California Department of Pesticide Regulation’s (DPR’s) risk assessments. -
Alumni Newsletter
ALUMNI NEWSLETTER lr II SCHOOL OF CHEMICAL SCIENCES I! UNIVERSITY OF ILLINOIS at Urbana-Champaign NO. 7, WINTER 1972-73 A Busy Week in June Seldom have so many worthy events been crowded into one week as have graced the people of the School of Chemical Sciences this June 9-15, 1972. Dr. H. E. Carter's portrait was hung in the Chemistry Library along with those of Parr, Noyes, and Adams; Dr. Philip Handler was honored at com mencement as a Distinguished Alumnus of the University; East Chemistry was dedicated as the Roger Adams Laboratory; and Alpha Chi Sigma held its Biennial National Conclave on our campus. Individually and in com bination these celebrations brought together in Urbana students, faculty, former faculty, alumni, distinguished guests, family, and friends from far corners. Roger Adams Laboratory Dedicated Several years ago, the Board of Trustees of the University ruled that campus buildings should have names that describe their function rather than names commemorating influential University people. Fortunately, however, the board modified this rule for a very special occasion last summer, and autho rized the changing of the name of East Chemistry Building to the Roger Adams Laboratory. The building was dedicated with this new name on Sun day, June 11, as the opening event of the Biennial National Conclave of the professional chemistry fraternity, Alpha Chi Sigma. Professor Gutowsky presided at the ceremony, introducing first Dr. J. W. Peltason, Chancellor of the Upiversity of Illinois at Urbana-Champaign, who paid tribute to Professor Adams and his work. Dr. Ernest Volwiler (Ph.D. -
Carl Djerassi: Chemist and Entrepreneur
Carl Djerassi: Chemist and entrepreneur Eugene Garfield 534 CHEMTECH SEPTEMBER 1983 Much has been said about the scientific entrepreneur. established a precedent for the widely used fragment coding Although the term ordinarily is applied to the person who system employed in the Index Chemicus Registry System has been successful in business—one thinks of Thomas (ICRS) and other systems. Edison or Edwin Land, among others—there also are At the end of the 1940s, much of the excitement centered scientific entrepreneurs in the academic community. It is on the discovery that cortisone could alleviate arthritis not often that one finds a scientist who can fit both symptoms. The chemical was derived from animal bile, but descriptions. To maintain a credible academic existence one initially in amounts too small for treating this chronic, needs enormous dedication and energy; to function in a widespread disease. Scientists around the world were racing scientifically oriented business these qualities as well as to find a more practical method of synthesis. In 1951, significant managerial competence are needed. That rare Djerassi and his team at Syntex won the race; they found a combination of qualities is found in my friend Carl relatively simple way to make cortisone using a readily Djerassi. available raw material, the Mexican yam (2). I recently had the honor of speaking informally at an That same year, Djerassi's team synthesized another unusual event. The numerous friends and collaborators of compound, which received much less attention at the time. Djerassi attended a party celebrating the publication of his They named it "norethisterone," and it was to become the thousandth paper. -
Badger Chemist
Est. 1953. NO. 55 2011 Badger Chemist THE NEWSLETTER OF THE UNIVERSITY OF WISCONSIN–MADISON media, education resources, & information technology CHEMISTRY DEPARTMENT THE NEWSLETTER OF THE UNIVERSITY OF WISCONSIN –MadisoN CHEMISTRY DEPARTMENT CONTENTS From the Chair ................................................ 1 New Badger Chemists ......................................... 2 Our Awards .................................................. 4 Notable News ................................................ 8 Partners in Giving Campaign ................................... 9 This ‘n’ That. ................................................. 10 New Assistant Professor Randy Goldsmith ........................ 11 Chemistry News. 12 Chemical Education Digital Library Activities. .................... 15 WISL Activities .. 17 Vedejs Reunion .............................................. 19 Zimmerman Group ........................................... 20 Zimmerman Reunion ......................................... 22 Featured Alumnus ............................................ 23 ICE (Institute for Chemical Education) ........................... 24 In Memoriam ................................................ 29 Chemistry Department Support. ................................ 37 Donors to Department Funds . ................................. 38 2011 BADGER CHEMIST Matthew Sanders Sue Martin-Zernicke Editor Editorial Assistant Designed by MERIT [Media, Education Resouces & Information Technology] School of Education, University of Wisconsin–Madison Est. 1953 -
MAY 03 Nucleus Sp-LAST
DED UN 18 O 98 F yyyy N yyyy Y O T R E I T H C E O yyyyN A E S S S L T A E A C R C I yyyyN S M S E E H C C T N IO A May 2003 Vol. LXXXI, No. 9 yyyyC N • AMERI Monthly Meeting Education Night at B.U. Guy Crosby speaks on Chemistry of Nutrition Election 2003 Election of candidates for 2004 Book Review Quantum Leaps in the Wrong Direction, by C. M. Wynn and A. W. Wiggins Historical Note Edward Frankland’s Crusade for Clean Water in the 19th Century template group. If this were true, then this end, a simple molecular modeling Meeting virtually any ring system which ful- exercise was undertaken to compare filled this requirement would lead to a the differences between our best com- series of potent inhibitors pound and those reported by Merck. Report We selected the 1H-pyrrole ring The simple overlay of these molecules From the April 10, 2003 Esselen system as our starting template to test revealed the presence of a methyl Award Address this hypothesis, primarily because group in the Merck compound in a these could readily be prepared from region of space not occupied by our The Discovery And 1,4-diketones through the classical inhibitors. Development Of Lipitor‚ Paal-Knorr condensation and these 1,4- To determine the importance of (Atorvastatin Calcium) diketones, in turn, were potentially occupying this space, bromine and available possessing a wide variety of chlorines were introduced into the 3- Bruce D. -
The 1990 Nobel Prize Winners
Current CX3mrnerits” EUGENE GARFIELD INSTITUTE FCR SCIENTIFIC INFORMATGW 3YJ1 MARKET ST PHILAOELFHIA, PA 19104 The 199Q Nobel Prize Winners: A Citationist Retrospective Number 11 March 18, 1991 For more than a decade, we have devoted Before the awards were announced last essays to each year’s Nobel Prizes. These year, the biweekly newspaper ?% Scien- reports, usually published six months or tkt @ published a series of axticles in which more after the prize, have provided a unique Nobel Prize contenders were listed, based citationist perspective on the wimers. In ad- on citation frequency and predictor dition to identifying their most-cited works, awards.$7 One would think that with all of especially Citation Clussics ~, we have the non-Nobel awards that abound,g.g there highlighted work that has influenced key re- would be few recipients not in that category. search fronts.1 Nevertheless, this does occur km time to When pertinent, we’ve also listed the time. winners’ contributions to the review litera- One interesting aspect of this year’s ture. And+whe~ possible, we’ve contacted awards is the relatively low level of citations the Nobelists or close colleagues to de- for several of the winners. This could be due termine whether or not our data rein- to factors similar to those of the famous forced or contradicted perceptions of de- Watson and Crick paper in 1953,10 for layed recognition, as in the case with which they teceived the 1%2 Nobel Prize in Barbara Mc(lintock.z Her 1983 Nobel for physiology or medicine. It had been cited physiology or medicine may have been de- just under 1,100 times when we last studied layed, but she was widely recognized in the it.11This is an indication of obliteration by genetics community. -
Date: To: September 22, 1 997 Mr Ian Johnston©
22-SEP-1997 16:36 NOBELSTIFTELSEN 4& 8 6603847 SID 01 NOBELSTIFTELSEN The Nobel Foundation TELEFAX Date: September 22, 1 997 To: Mr Ian Johnston© Company: Executive Office of the Secretary-General Fax no: 0091-2129633511 From: The Nobel Foundation Total number of pages: olO MESSAGE DearMrJohnstone, With reference to your fax and to our telephone conversation, I am enclosing the address list of all Nobel Prize laureates. Yours sincerely, Ingr BergstrSm Mailing address: Bos StU S-102 45 Stockholm. Sweden Strat itddrtSMi Suircfatan 14 Teleptelrtts: (-MB S) 663 » 20 Fsuc (*-«>!) «W Jg 47 22-SEP-1997 16:36 NOBELSTIFTELSEN 46 B S603847 SID 02 22-SEP-1997 16:35 NOBELSTIFTELSEN 46 8 6603847 SID 03 Professor Willis E, Lamb Jr Prof. Aleksandre M. Prokhorov Dr. Leo EsaJki 848 North Norris Avenue Russian Academy of Sciences University of Tsukuba TUCSON, AZ 857 19 Leninskii Prospect 14 Tsukuba USA MSOCOWV71 Ibaraki Ru s s I a 305 Japan 59* c>io Dr. Tsung Dao Lee Professor Hans A. Bethe Professor Antony Hewlsh Department of Physics Cornell University Cavendish Laboratory Columbia University ITHACA, NY 14853 University of Cambridge 538 West I20th Street USA CAMBRIDGE CB3 OHE NEW YORK, NY 10027 England USA S96 014 S ' Dr. Chen Ning Yang Professor Murray Gell-Mann ^ Professor Aage Bohr The Institute for Department of Physics Niels Bohr Institutet Theoretical Physics California Institute of Technology Blegdamsvej 17 State University of New York PASADENA, CA91125 DK-2100 KOPENHAMN 0 STONY BROOK, NY 11794 USA D anni ark USA 595 600 613 Professor Owen Chamberlain Professor Louis Neel ' Professor Ben Mottelson 6068 Margarldo Drive Membre de rinstitute Nordita OAKLAND, CA 946 IS 15 Rue Marcel-Allegot Blegdamsvej 17 USA F-92190 MEUDON-BELLEVUE DK-2100 KOPENHAMN 0 Frankrike D an m ar k 599 615 Professor Donald A. -
Chemistry Behind the Magic
Bassam Z. Shakhashiri is the first holder of the William T. Evjue Distinguished Chair for the Wisconsin Idea at UW-Madison. He is well known internationally for his effective leadership in promoting excellence in science education at all levels, and for his development and use of demonstrations in the teaching of chemistry in classrooms as well as in less formal settings, such as museums, convention centers, shopping malls and retirement homes. The Encyclopedia Britannica sites him as the "dean of lecture demonstrators in America." His scholarly publications, including the multi-volume series, Chemical Demonstrations: A Handbook for Teachers of Chemistry, are models of learning and instruction that have been translated into several languages. He is an advocate for policies to advance knowledge and to use science and technology to serve society. He promotes the exploration and establishment of links between science, the arts and the humanities, and the elevation of discourse on significant societal issues related to science, religion, politics, the economy, and ethics. Professor Shakhashiri is the 2011 President-Elect of the American Chemical Society, and will serve one-year terms as president in 2012 and immediate past president in 2013. A native of (Anfe, El-Koura) Lebanon, Professor Shakhashiri is the son of the late Dr. Zekin A. Shakhashiri, a pioneer in public health at the American University of Beirut, and the late Adma N. Shakhashiri, an alumna of what is now Lebanese American University. The Shakhashiris -- father, mother, son and two daughters, Amal and Maha -- came to the United States in 1957 when Bassam was 17 years old with one year of college (at the American University of Beirut) behind him. -
A Retirement Celebration Honoring Prof. Robert K. Boeckman, Jr
A Retirement Celebration Honoring Prof. Robert K. Boeckman, Jr. Symposium Lander Auditorium, 9:00 am — 5:00 pm Lunch Munnerlyn Atrium, 12:30 pm Cocktail Reception/Dinner Oakhill Country Club, 6:30 pm Robert K. Boeckman, Jr. was born August 26, 1944 in Pasadena, California. After early schooling in Dayton, Ohio, he received his Bachelors of Science degree in Chemistry in 1966 from Carnegie Institute of Technology (now Carnegie Mellon University). He moved on to Brandeis University where he received the Ph.D. degree under the supervision of James B. Hendrickson and Ernest Grunwald in 1970. He then joined the research group of Gilbert Stork in 1970 as an NIH postdoctoral fellow. He began his academic career at Wayne State University in 1972, where he rose to the rank of Professor in 1979. In 1980, he joined the faculty of the University of Rochester where he is currently Marshall D. Gates Jr. Professor of Chemistry. In 1976, he was married to Mary H. Delton. Among his academic honors are included an A.P. Sloan Fellowship, a Research Career Development Award from the National Institutes of Health, and an ACS Cope Scholar Award. He has been a Fellow of the Japanese Society for the Promotion of Science, was twice awarded an Alexander Von Humboldt Stiftung Research Prize for Senior Scientists, and named a Marshall Gates Scholar by the University of Rochester. He is an inaugural ACS Fellow and a Fellow of the AAAS. From 1997 until 2016, he served as an Associate Editor of the Journal of Organic Chemistry. He served as Chair of the Department of Chemistry at the University of Rochester from 2003-2013 and in 2009 received the William H.