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TABLE OF CONTENTS Programme……………………………………………………………………….. 2 Keynote lectures……………………………………………………………….. 4 Albert Zink ……………………………………………………….………… 4 Frank Rühli ..………………………………………………………………. 4 Kenny Rodriguez- Wallberg………………………………………… 6 Edward Malec…………………………………………...……………….. 8 Victor Ruiz-Velasco…………………………………………............. 9 Elena Herrero Hernandez………………………………............. 11 Debate …………………............................................................ 14 Workshops……………………………………………………………………… 15 Workshop Programme……………………………………………….. 15 Social Programme……………………………………………………………… 18 Rules of Presentation………………………………………………………… 21 Awards……………………………………………………………………........... 21 Plenary Session..................................................................... 22 Practical Info……………………………………………………………………… 23 World Health Summit…………………………………………………………27 Congress venue..................................................................... 29 Useful Polish Phrases………………………………………………………… 30 1 PROGRAMME 2 PROGRAMME 3 KEYNOTE LECTURES May 11th, 18:00-19:30 Albert Zink Scientific Director at the Institute for Mummies and the Iceman in Bozen/Bolzano Research Interests: biological and biomolecular anthropology, nanotechnologies, paleopathology, paleoepidemiology and forensic studies. Albert Zink is well known from revealing the truth of Tutankhamun’s family, Egyptian pharaoh of the 18th dynasty (ruled ca. 1332–1323 BC in the conventional chronology), during the period of Egyptian history known as the New Kingdom, as well as developing the investigations in the Capuchin Catacombs of Palermo in Sicily, Italy. Nowadays he works on a new project concerning the sacral topography of a monastic landscape and its development on the hill of Dra’ Abu el- Naga (Upper Egypt: Deir el-Bakhît and the Theban monastery of Saint Paulos). Frank Rühli Head of the Institute of Evolutionary Medicine (IEM) of the University of Zurich and Vice-President of the Swiss Society of Anthropology, also Associated Editor, Editor and Editor–in-Chief of six peer-reviewed journals 4 Research Interests: clinical anatomy, paleoradiology, and paleopathology (especially ancient mummy studies). Frank Rühli studied Medicine at the University of Zurich. After graduation he was awarded an International Postgraduate Research Scholarship to undertake a PhD at the Biological Anthropology and Comparative Anatomy Research Unit, Anatomical Sciences at the University of Adelaide (Australia), where he also held a full-time lectureship. After home-coming, he worked at the Institute of Anatomy in the University of Zürich, finishing his habilitation (“DSc”) on “Evidence-based paleopathology”. From 2010–2014 he co-headed the “Swiss Mummy Project”, headed the Centre for Evolutionary Medicine (ZEM). Latest research and teaching issue. Evolutionary Medicine is a novel field of research within the Medical faculty. By applying principles form evolutionary biology one can address the evolution of human health, changes in pathogens or enigmatic etiologies of human disease. In this presentation, latest results in these fields as undertaken at the worldwide unique Institute of Evolutionary Medicine, University of Zurich will be presented. Also, how the field of evolutionary medicine has been incorporated within the medical faculty will be shown. Finally, the various curricula developed for medical and science students will be highlighted too. 5 Kenny Rodriguez-Wallberg Associate Professor and Researcher at the Department of Oncology and Pathology and Senior Consultant at Karolinska University Hospital, Stockholm Research Interests: fertility preservation in cancer patients Kenny Rodriguez Wallberg obtained her degree in Obstetrics and Gynaecology in Colombia. Then she completed her training in Paris at the Cochin-Baudelocque (Infertility and Assisted Reproduction) and at the Necker and Hôtel Dieu Hospitals (Paediatric and Reproductive Endocrinology) thanks to the fellowship from the GFGEA. She earned her PhD degree at Uppsala University in Sweden. Since 2007, she works in the Karolinska Hospital as a senior consultant in Reproductive Medicine who is responsible for the clinical programme of Fertility Preservation. Her researches have been supported by the Swedish Society of Medical Research (SSMF) as a postdoctoral grant, The Swedish Research Council Grant for Young Investigators and currently by The Stockholm County council and The Swedish Childhood Cancer Foundation. 6 May 12th, 10:45 Fertility preservation: Applying current knowledge on reproductive technologies for the building of future families Improvements in cancer therapy are resulting in an increasing number of long-term cancer survivors, and all quality-of-life aspects including the option to preserve fertility have become of major importance when treating young people with cancer. The development of Assisted Reproductive Technologies (ART) has included the establishment of methods for freezing of sperm, supernumerary embryos and oocytes, and those procedures are currently being practiced as clinical routines at reproductive clinics worldwide. The methods are today available for young cancer patients when facing the risk of becoming infertile as a consequence of the gonadal damage inherent to cancer treatment. The methods may also be offered to young patients that will undergo treatments with cytotoxic drugs indicated for benign or chronic diseases, or to people with a genetic predisposition to develop premature gonadal failure and infertility. Additional methods used for fertility preservation include the freezing of ovarian tissue, with the aim to tissue transplantation, which has demonstrated feasible, but is still considered as an experimental option. The practice of fertility preservation is currently increasing and several international medical societies have produced guidelines and recommendations. Availability and access to fertility preservation differ between the countries, and several barriers have been identified in healthcare for the provision of these services. The lecture will discuss all relevant aspects associated with this practice. 7 Edward Malec Professor Westfalische Wilhelms Universität Münster, Head of Children’s Cardiac Surgery Clinic, Congenital Heart Defects Surgery Universitätsklinikum Münster, co-author and editor of the guide for parents "Child with a heart defect" Research Interests: cardiology, cardiac surgery, transplantology Edward Malec graduated from Medical Academy in Kraków. He has improved his skills in prestigious medical centers in Europe and the United States of America (Aldo Castaneda Institute of Clinique de Genolieur, Children's Hospital of Philadelphia Children's Hospital, Boston Children's Hospital Washington National Heart). Nowadays he is world famous Polish cardio-surgeon. He performed in Poland, the United States, Slovakia, Norway, Switzerland and Germany over 6,000 complicated cardiac surgeries on children with heart disease. He has won numerous awards for his work, three times considered one of the best doctors in Germany by Focus, last but not least, honoured with ‘Order of the Smile’ (granted by the rescued children from around the world). May 12th, 14:00 Life with half of the heart- a man-made circulation 8 Victor Ruiz-Velasco Professor and Associate Vice Chairman for Basic Science Research of the Department of Anaesthesiology and Perioperative Medicine at the University Drive Hershey, Penn State Hershey Medical Center Research Interests: basic science research , neural and behavioural sciences, pharmacology Victor Ruiz-Velasco obtained his PhD degree in Tulane University School of Medicine. He was then completing the postdoctoral training at the University of Nevada at Reno as well as the Guthrie Research Institute. His studies are focused on the mechanisms by which second messengers, particularly G proteins, modulate voltage-dependent N- type Ca2. May 13th, 10:45 Endogenous opioids potentiate acid-sensing ion channel (ASIC) currents: its implications in a rat model of hindlimb ischemia. The naturally occurring endomorphins 1 and 2 (E-1 and E-2) exhibit high affinity and selectivity for mu opioid receptors (MOR). Both tetrapeptides exert analgesic properties in some animal models of pain. E-1 and E-2 release is enhanced under ischemic and inflammatory conditions. Additionally, a pH drop in ischemic tissue activates the H+-gated acid sensing ion channels (ASIC). ASIC are expressed primarily in peripheral and central nervous system. Some reports have shown that dorsal root ganglion (DRG) neurons express primarily ASIC1 and ASIC3 isoforms. ASIC3 channel currents are 9 characterized by two components: fast component that rapidly desensitizes and a slow, sustained current that lasts as long as the external pH remains acidic. The purpose of the present study was to examine the effect of E-1 and E-2 peptides on ASIC channel currents employing the whole-cell variant of the patch-clamp technique. In acutely isolated rat DRG neurons, exposure to either 10 M E1 or E2 (pH 6.0) enhanced the sustained ASIC currents 76+29% (n=11) and 113+35% (n=17), respectively, when compared to activation by pH 6.0 alone. The sustained ASIC currents also were potentiated (115+39%, n=5) by E-2 (10 M) in DRG neurons pretreated overnight with pertussis toxin—suggesting that MOR were not involved in this signaling event. In order to better understand the effect of endomorphins on ASIC3 homotrimers alone, ASIC3 channels were heterologously expressed in the mouse fibroblast L cell line that does not natively express MOR or ASIC