Appendix 2. Co-investigators (Members of the China Kadoorie Biobank

collaborative group)

Name Location Role Contribution Rory Collins, MBBS, University of Oxford, Oxford, International Steering Study design and MSc UK Committee coordination Richard Peto, MD, University of Oxford, Oxford, International Steering Study design and MSc UK Committee coordination Robert Clarke, MD, University of Oxford, Oxford, International Steering Study design and MSc UK Committee coordination Robin Walters, PhD University of Oxford, Oxford, International Steering Study design and UK Committee coordination Xiao Han, BSc Chinese Academy of Medical Member of National Co- Data cleaning, verification, Sciences, Beijing, China ordinating Centre, Beijing and coordination Can Hou, BSc Chinese Academy of Medical Member of National Co- Data cleaning, verification, Sciences, Beijing, China ordinating Centre, Beijing and coordination Biao Jing, BSc Chinese Academy of Medical Member of National Co- Data cleaning, verification, Sciences, Beijing, China ordinating Centre, Beijing and coordination Chao Liu, BSc Chinese Academy of Medical Member of National Co- Data cleaning, verification, Sciences, Beijing, China ordinating Centre, Beijing and coordination Pei Pei, BSc Chinese Academy of Medical Member of National Co- Data cleaning, verification, Sciences, Beijing, China ordinating Centre, Beijing and coordination Yunlong Tan, BSc Chinese Academy of Medical Member of National Co- Data cleaning, verification, Sciences, Beijing, China ordinating Centre, Beijing and coordination Daniel Avery, MSc, University of Oxford, Oxford, Member of International Co- Data cleaning and BSc UK ordinating Centre, Oxford coordination Derrick Bennett, PhD, University of Oxford, Oxford, Member of International Co- Data cleaning and MSc, BSc UK ordinating Centre, Oxford coordination Ruth Boxall, MSc University of Oxford, Oxford, Member of International Co- Data cleaning and UK ordinating Centre, Oxford coordination Fiona Bragg, PhD, University of Oxford, Oxford, Member of International Co- Data cleaning and MD, MSc, BSc(Hons) UK ordinating Centre, Oxford coordination Yumei Chang, PhD University of Oxford, Oxford, Member of International Co- Data cleaning and UK ordinating Centre, Oxford coordination Huaidong Du, PhD, University of Oxford, Oxford, Member of International Co- Data cleaning and MSc UK ordinating Centre, Oxford coordination Simon Gilbert, MA, University of Oxford, Oxford, Member of International Co- Data cleaning and MSc, BSc UK ordinating Centre, Oxford coordination Alex Hacker, University of Oxford, Oxford, Member of International Co- Data cleaning and BA(Hons) UK ordinating Centre, Oxford coordination Michael Holmes, University of Oxford, Oxford, Member of International Co- Data cleaning and PhD, MSc, MBBS, UK ordinating Centre, Oxford coordination BSC(Hons) Name Location Role Contribution Christiana Kartsonaki, University of Oxford, Oxford, Member of International Co- Data cleaning and PhD UK ordinating Centre, Oxford coordination Rene Kerosi, MSc University of Oxford, Oxford, Member of International Co- Data cleaning and UK ordinating Centre, Oxford coordination Garry Lancaster, MA University of Oxford, Oxford, Member of International Co- Data cleaning and UK ordinating Centre, Oxford coordination Kuang Lin, PhD University of Oxford, Oxford, Member of International Co- Data cleaning and UK ordinating Centre, Oxford coordination John McDonnell, University of Oxford, Oxford, Member of International Co- Data cleaning and Diploma UK ordinating Centre, Oxford coordination Iona Millwood, PhD University of Oxford, Oxford, Member of International Co- Data cleaning and UK ordinating Centre, Oxford coordination Qunhua Nie, BSc University of Oxford, Oxford, Member of International Co- Data cleaning and UK ordinating Centre, Oxford coordination Jayakrishnan University of Oxford, Oxford, Member of International Co- Data cleaning and Radhakrishnan, UK ordinating Centre, Oxford coordination BA(Hons) Paul Ryder, University of Oxford, Oxford, Member of International Co- Data cleaning and BA(Hons) UK ordinating Centre, Oxford coordination Sam Sansome, MSc, University of Oxford, Oxford, Member of International Co- Data cleaning and BSc UK ordinating Centre, Oxford coordination Dan Schmidt, BSc University of Oxford, Oxford, Member of International Co- Data cleaning and UK ordinating Centre, Oxford coordination Rajani Sohoni, MD, University of Oxford, Oxford, Member of International Co- Data cleaning and BA(Hons) UK ordinating Centre, Oxford coordination Iain Turnbull, MD University of Oxford, Oxford, Member of International Co- Data cleaning and UK ordinating Centre, Oxford coordination Jenny Wang, MA, University of Oxford, Oxford, Member of International Co- Data cleaning and BSc UK ordinating Centre, Oxford coordination Lin Wang, PhD University of Oxford, Oxford, Member of International Co- Data cleaning and UK ordinating Centre, Oxford coordination Neil Wright, PhD University of Oxford, Oxford, Member of International Co- Data cleaning and UK ordinating Centre, Oxford coordination Xiaoming Yang, PhD University of Oxford, Oxford, Member of International Co- Data cleaning and UK ordinating Centre, Oxford coordination Zengchang Pang, BSc Qingdao CDC, Qingdao, Member of Regional Co- Data collection and China ordinating Centres verification Ruqin Gao, MSc Qingdao CDC, Qingdao, Member of Regional Co- Data collection and China ordinating Centres verification Shanpeng Li, MSc Qingdao CDC, Qingdao, Member of Regional Co- Data collection and China ordinating Centres verification Shaojie Wang, BSc Qingdao CDC, Qingdao, Member of Regional Co- Data collection and China ordinating Centres verification Yongmei Liu, BSc Qingdao CDC, Qingdao, Member of Regional Co- Data collection and China ordinating Centres verification Name Location Role Contribution Ranran Du, Associate Qingdao CDC, Qingdao, Member of Regional Co- Data collection and degree China ordinating Centres verification Yajing Zang, Qingdao CDC, Qingdao, Member of Regional Co- Data collection and Associate degree China ordinating Centres verification Liang Cheng, PhD Qingdao CDC, Qingdao, Member of Regional Co- Data collection and China ordinating Centres verification Xiaocao Tian, MSc Qingdao CDC, Qingdao, Member of Regional Co- Data collection and China ordinating Centres verification Hua Zhang, MSc Qingdao CDC, Qingdao, Member of Regional Co- Data collection and China ordinating Centres verification Yaoming Zhai, BSc Qingdao CDC, Qingdao, Member of Regional Co- Data collection and China ordinating Centres verification Xiaohui Sun, MSc Qingdao CDC, Qingdao, Member of Regional Co- Data collection and China ordinating Centres verification Feifei Li, BSc Qingdao CDC, Qingdao, Member of Regional Co- Data collection and China ordinating Centres verification Silu Lv, BSc Licang CDC, Qingdao, China Member of Regional Co- Data collection and ordinating Centres verification Junzheng Wang, BSc Licang CDC, Qingdao, China Member of Regional Co- Data collection and ordinating Centres verification Wei Hou, BSc Licang CDC, Qingdao, China Member of Regional Co- Data collection and ordinating Centres verification Mingyuan Zou, BSc Heilongjiang CDC, Harbin, Member of Regional Co- Data collection and China ordinating Centres verification Ge Jiang, BSc Heilongjiang CDC, Harbin, Member of Regional Co- Data collection and China ordinating Centres verification Xue Zhou, PhD Heilongjiang CDC, Harbin, Member of Regional Co- Data collection and China ordinating Centres verification Liqiu Yang, MSc Nangang CDC, Harbin, China Member of Regional Co- Data collection and ordinating Centres verification Hui He, MSc Nangang CDC, Harbin, China Member of Regional Co- Data collection and ordinating Centres verification Bo Yu, BSc Nangang CDC, Harbin, China Member of Regional Co- Data collection and ordinating Centres verification Yanjie Li, BSc Nangang CDC, Harbin, China Member of Regional Co- Data collection and ordinating Centres verification Qinai Xu, BSc Nangang CDC, Harbin, China Member of Regional Co- Data collection and ordinating Centres verification Quan Kang, BSc Nangang CDC, Harbin, China Member of Regional Co- Data collection and ordinating Centres verification Ziyan Guo, Associate Nangang CDC, Harbin, China Member of Regional Co- Data collection and degree ordinating Centres verification Dan Wang, BSc Hainan Provincial CDC, Member of Regional Co- Data collection and Haikou, China ordinating Centres verification Ximin Hu, MSc Hainan Provincial CDC, Member of Regional Co- Data collection and Name Location Role Contribution Haikou, China ordinating Centres verification Hongmei Wang, MSc Hainan Provincial CDC, Member of Regional Co- Data collection and Haikou, China ordinating Centres verification Jinyan Chen, MSc Hainan Provincial CDC, Member of Regional Co- Data collection and Haikou, China ordinating Centres verification Yan Fu, BSc Hainan Provincial CDC, Member of Regional Co- Data collection and Haikou, China ordinating Centres verification Zhenwang Fu, MSc Hainan Provincial CDC, Member of Regional Co- Data collection and Haikou, China ordinating Centres verification Xiaohuan Wang, BSc Hainan Provincial CDC, Member of Regional Co- Data collection and Haikou, China ordinating Centres verification Min Weng, BSc Meilan CDC, Meilan, Member of Regional Co- Data collection and Haikou, China ordinating Centres verification Zhendong Guo, Meilan CDC, Meilan, Member of Regional Co- Data collection and Associate degree Haikou, China ordinating Centres verification Shukuan Wu, BSc Meilan CDC, Meilan, Member of Regional Co- Data collection and Haikou, China ordinating Centres verification Yilei Li, Associate Meilan CDC, Meilan, Member of Regional Co- Data collection and degree Haikou, China ordinating Centres verification Huimei Li, BSc Meilan CDC, Meilan, Member of Regional Co- Data collection and Haikou, China ordinating Centres verification Zhifang Fu, Associate Meilan CDC, Meilan, Member of Regional Co- Data collection and degree Haikou, China ordinating Centres verification Ming Wu, PhD Jiangsu Provincial CDC, Member of Regional Co- Data collection and Nanjing, China ordinating Centres verification Yonglin Zhou, MSc Jiangsu Provincial CDC, Member of Regional Co- Data collection and Nanjing, China ordinating Centres verification Jinyi Zhou, MSc Jiangsu Provincial CDC, Member of Regional Co- Data collection and Nanjing, China ordinating Centres verification Ran Tao, PhD Jiangsu Provincial CDC, Member of Regional Co- Data collection and Nanjing, China ordinating Centres verification Jie Yang, MSc Jiangsu Provincial CDC, Member of Regional Co- Data collection and Nanjing, China ordinating Centres verification Jian Su, BSc Jiangsu Provincial CDC, Member of Regional Co- Data collection and Nanjing, China ordinating Centres verification Fang Liu, BSc Wuzhong CDC, Wuzhong, Member of Regional Co- Data collection and Suzhou, China ordinating Centres verification Jun Zhang, BSc Wuzhong CDC, Wuzhong, Member of Regional Co- Data collection and Suzhou, China ordinating Centres verification Yihe Hu, BSc Wuzhong CDC, Wuzhong, Member of Regional Co- Data collection and Suzhou, China ordinating Centres verification Yan Lu, BSc Wuzhong CDC, Wuzhong, Member of Regional Co- Data collection and Suzhou, China ordinating Centres verification Liangcai Ma, BSc Wuzhong CDC, Wuzhong, Member of Regional Co- Data collection and Suzhou, China ordinating Centres verification Name Location Role Contribution Aiyu Tang, BSc Wuzhong CDC, Wuzhong, Member of Regional Co- Data collection and Suzhou, China ordinating Centres verification Shuo Zhang, BSc Wuzhong CDC, Wuzhong, Member of Regional Co- Data collection and Suzhou, China ordinating Centres verification Jianrong Jin, BSc Wuzhong CDC, Wuzhong, Member of Regional Co- Data collection and Suzhou, China ordinating Centres verification Jingchao Liu, MSc Wuzhong CDC, Wuzhong, Member of Regional Co- Data collection and Suzhou, China ordinating Centres verification Zhenzhu Tang, MSc Guangxi Provincial CDC, Member of Regional Co- Data collection and Nanning, China ordinating Centres verification Naying Chen, BSc Guangxi Provincial CDC, Member of Regional Co- Data collection and Nanning, China ordinating Centres verification Ying Huang, MSc Guangxi Provincial CDC, Member of Regional Co- Data collection and Nanning, China ordinating Centres verification Mingqiang Li, BSc Liuzhou CDC, Liubei, Member of Regional Co- Data collection and Liuzhou, China ordinating Centres verification Jinhuai Meng, Liuzhou CDC, Liubei, Member of Regional Co- Data collection and Associate degree Liuzhou, China ordinating Centres verification Rong Pan, MSc Liuzhou CDC, Liubei, Member of Regional Co- Data collection and Liuzhou, China ordinating Centres verification Qilian Jiang, BSc Liuzhou CDC, Liubei, Member of Regional Co- Data collection and Liuzhou, China ordinating Centres verification Jian Lan, BSc Liuzhou CDC, Liubei, Member of Regional Co- Data collection and Liuzhou, China ordinating Centres verification Yun Liu, BSc Liuzhou CDC, Liubei, Member of Regional Co- Data collection and Liuzhou, China ordinating Centres verification Liuping Wei, BSc Liuzhou CDC, Liubei, Member of Regional Co- Data collection and Liuzhou, China ordinating Centres verification Liyuan Zhou, Liuzhou CDC, Liubei, Member of Regional Co- Data collection and Associate degree Liuzhou, China ordinating Centres verification Ningyu Chen, BSc Liuzhou CDC, Liubei, Member of Regional Co- Data collection and Liuzhou, China ordinating Centres verification Ping Wang, BSc Liuzhou CDC, Liubei, Member of Regional Co- Data collection and Liuzhou, China ordinating Centres verification Fanwen Meng, BSc Liuzhou CDC, Liubei, Member of Regional Co- Data collection and Liuzhou, China ordinating Centres verification Yulu Qin, BSc Liuzhou CDC, Liubei, Member of Regional Co- Data collection and Liuzhou, China ordinating Centres verification Sisi Wang, BSc Liuzhou CDC, Liubei, Member of Regional Co- Data collection and Liuzhou, China ordinating Centres verification Xianping Wu, MSc Sichuan Provincial CDC, Member of Regional Co- Data collection and Chengdu, China ordinating Centres verification Ningmei Zhang, Sichuan Provincial CDC, Member of Regional Co- Data collection and Associate degree Chengdu, China ordinating Centres verification Xiaofang Chen, MSc Sichuan Provincial CDC, Member of Regional Co- Data collection and Name Location Role Contribution Chengdu, China ordinating Centres verification Weiwei Zhou, MSc Sichuan Provincial CDC, Member of Regional Co- Data collection and Chengdu, China ordinating Centres verification Guojin Luo, Associate Pengzhou CDC, Pengzhou, Member of Regional Co- Data collection and degree Chengdu, China ordinating Centres verification Jianguo Li, Associate Pengzhou CDC, Pengzhou, Member of Regional Co- Data collection and degree Chengdu, China ordinating Centres verification Xiaofang Chen, BSc Pengzhou CDC, Pengzhou, Member of Regional Co- Data collection and Chengdu, China ordinating Centres verification Xunfu Zhong, BSc Pengzhou CDC, Pengzhou, Member of Regional Co- Data collection and Chengdu, China ordinating Centres verification Jiaqiu Liu, BSc Pengzhou CDC, Pengzhou, Member of Regional Co- Data collection and Chengdu, China ordinating Centres verification Qiang Sun, BSc Pengzhou CDC, Pengzhou, Member of Regional Co- Data collection and Chengdu, China ordinating Centres verification Pengfei Ge, MSc Gansu Provincial CDC, Member of Regional Co- Data collection and Lanzhou, China ordinating Centres verification Xiaolan Ren, BSc Gansu Provincial CDC, Member of Regional Co- Data collection and Lanzhou, China ordinating Centres verification Caixia Dong, PhD Gansu Provincial CDC, Member of Regional Co- Data collection and Lanzhou, China ordinating Centres verification Hui Zhang, MSc Maijixiang CDC, Maijixiang, Member of Regional Co- Data collection and Tianshui, China ordinating Centres verification Enke Mao, BSc Maijixiang CDC, Maijixiang, Member of Regional Co- Data collection and Tianshui, China ordinating Centres verification Xiaoping Wang, Maijixiang CDC, Maijixiang, Member of Regional Co- Data collection and Associate degree Tianshui, China ordinating Centres verification Tao Wang, BSc Maijixiang CDC, Maijixiang, Member of Regional Co- Data collection and Tianshui, China ordinating Centres verification Xi Zhang, BSc Maijixiang CDC, Maijixiang, Member of Regional Co- Data collection and Tianshui, China ordinating Centres verification Ding Zhang, MSc Henan Provincial CDC, Member of Regional Co- Data collection and Zhengzhou, China ordinating Centres verification Gang Zhou, MSc Henan Provincial CDC, Member of Regional Co- Data collection and Zhengzhou, China ordinating Centres verification Shixian Feng, BSc Henan Provincial CDC, Member of Regional Co- Data collection and Zhengzhou, China ordinating Centres verification Liang Chang, MSc Henan Provincial CDC, Member of Regional Co- Data collection and Zhengzhou, China ordinating Centres verification Lei Fan, MSc Henan Provincial CDC, Member of Regional Co- Data collection and Zhengzhou, China ordinating Centres verification Yulian Gao, Associate Huixian CDC, Huixian, Member of Regional Co- Data collection and degree China ordinating Centres verification Tianyou He, Huixian CDC, Huixian, Member of Regional Co- Data collection and Associate degree China ordinating Centres verification Name Location Role Contribution Huarong Sun, BSc Huixian CDC, Huixian, Member of Regional Co- Data collection and China ordinating Centres verification Pan He, Associate Huixian CDC, Huixian, Member of Regional Co- Data collection and degree China ordinating Centres verification Chen Hu, Associate Huixian CDC, Huixian, Member of Regional Co- Data collection and degree China ordinating Centres verification Xukui Zhang, Huixian CDC, Huixian, Member of Regional Co- Data collection and Associate degree China ordinating Centres verification Huifang Wu, Huixian CDC, Huixian, Member of Regional Co- Data collection and Associate degree China ordinating Centres verification Min Yu, MSc Zhejiang Provincial CDC, Member of Regional Co- Data collection and Hangzhou, China ordinating Centres verification Ruying Hu, BSc Zhejiang Provincial CDC, Member of Regional Co- Data collection and Hangzhou, China ordinating Centres verification Hao Wang, MSc Zhejiang Provincial CDC, Member of Regional Co- Data collection and Hangzhou, China ordinating Centres verification Yijian Qian, BSc Tongxiang CDC, Tongxiang, Member of Regional Co- Data collection and China ordinating Centres verification Chunmei Wang, BSc Tongxiang CDC, Tongxiang, Member of Regional Co- Data collection and China ordinating Centres verification Kaixu Xie, BSc Tongxiang CDC, Tongxiang, Member of Regional Co- Data collection and China ordinating Centres verification Lingli Chen, BSc Tongxiang CDC, Tongxiang, Member of Regional Co- Data collection and China ordinating Centres verification Yidan Zhang, BSc Tongxiang CDC, Tongxiang, Member of Regional Co- Data collection and China ordinating Centres verification Dongxia Pan, MSc Tongxiang CDC, Tongxiang, Member of Regional Co- Data collection and China ordinating Centres verification Qijun Gu, BSc Tongxiang CDC, Tongxiang, Member of Regional Co- Data collection and China ordinating Centres verification Yuelong Huang, BSc Hunan Provincial CDC, Member of Regional Co- Data collection and Changsha, China ordinating Centres verification Biyun Chen, BSc Hunan Provincial CDC, Member of Regional Co- Data collection and Changsha, China ordinating Centres verification Li Yin, MSc Hunan Provincial CDC, Member of Regional Co- Data collection and Changsha, China ordinating Centres verification Huilin Liu, BSc Hunan Provincial CDC, Member of Regional Co- Data collection and Changsha, China ordinating Centres verification Zhongxi Fu, BSc Hunan Provincial CDC, Member of Regional Co- Data collection and Changsha, China ordinating Centres verification Qiaohua Xu, BSc Hunan Provincial CDC, Member of Regional Co- Data collection and Changsha, China ordinating Centres verification Xin Xu, BSc Liuyang CDC, Liuyang, Member of Regional Co- Data collection and China ordinating Centres verification Hao Zhang, Associate Liuyang CDC, Liuyang, Member of Regional Co- Data collection and Name Location Role Contribution degree China ordinating Centres verification Huajun Long, BSc Liuyang CDC, Liuyang, Member of Regional Co- Data collection and China ordinating Centres verification Xianzhi Li, BSc Liuyang CDC, Liuyang, Member of Regional Co- Data collection and China ordinating Centres verification Libo Zhang, BSc Liuyang CDC, Liuyang, Member of Regional Co- Data collection and China ordinating Centres verification Zhe Qiu, BSc Liuyang CDC, Liuyang, Member of Regional Co- Data collection and China ordinating Centres verification