Mendel and Darwin: Untangling a Persistent Enigma
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Aristotle's Essentialism Revisited
University of Missouri, St. Louis IRL @ UMSL Theses Graduate Works 4-15-2013 Accommodating Species Evolution: Aristotle’s Essentialism Revisited Yin Zhang University of Missouri-St. Louis, [email protected] Follow this and additional works at: http://irl.umsl.edu/thesis Recommended Citation Zhang, Yin, "Accommodating Species Evolution: Aristotle’s Essentialism Revisited" (2013). Theses. 192. http://irl.umsl.edu/thesis/192 This Thesis is brought to you for free and open access by the Graduate Works at IRL @ UMSL. It has been accepted for inclusion in Theses by an authorized administrator of IRL @ UMSL. For more information, please contact [email protected]. Accommodating Species Evolution: Aristotle’s Essentialism Revisited by Yin Zhang B.A., Philosophy, Peking University, 2010 A Thesis Submitted to The Graduate School at the University of Missouri – St. Louis in partial fulfillment of the requirements for the degree Master of Arts in Philosophy May 2013 Advisory Committee Jon D. McGinnis, Ph.D. Chairperson Andrew G. Black, Ph.D. Berit O. Brogaard, Ph.D. Zhang, Yin, UMSL, 2013, p. i PREFACE In the fall of 2008 when I was a junior at Peking University, I attended a lecture series directed by Dr. Melville Y. Stewart on science and religion. Guest lecturers Dr. Alvin Plantinga, Dr. William L. Craig and Dr. Bruce Reichenbach have influenced my thinking on the relation between evolution and faith. In the fall of 2010 when I became a one-year visiting student at Calvin College in Michigan, I took a seminar directed by Dr. Kelly J. Clark on evolution and ethics. Having thought about evolution/faith and evolution/ethics, I signed up for Dr. -
Nature Medicine Essay
COMMENTARY LASKER BASIC MEDICAL RESEARCH AWARD Of maize and men, or peas and people: case histories to justify plants and other model systems David Baulcombe One of the byproducts of molecular biology cork is altogether filled with air, and that air is has been support for the ‘model system’ con- perfectly enclosed in little boxes or cells distinct cept. All living organisms are based on the same from one another.”)2 (Fig. 1). Two hundred fifty genetic code, they have similar subcellular years later, Beijerinck discovered a contagium structures and they use homologous metabolic vivum fluidum in extracts of diseased tobacco pathways. So, mechanisms can be investigated plants that he later referred to as a virus3. using organisms other than those in which In contemporary science, a green alga— the knowledge will be exploited for practical Chlamydomonas reinhardtii—is a useful model benefit. Model systems are particularly use- in the analysis of kidney disease4. However, ful in the early discovery phase of a scientific in this article, I refer to the contribution of endeavor, and recent progress in biomedical plant biology to a family of mechanisms that I science has fully vindicated their use. Jacques refer to as RNA silencing. This topic has been Monod, for example, famously justified his reviewed comprehensively elsewhere5,6, so here work on a bacterial model system by stating I focus on personal experience and my view of that “what is true for Escherichia coli is also future potential from this work. true for elephants.” My fellow laureates, Victor Ambros and Gary Ruvkun, can defend the use The early history of RNA silencing in of the worm Caenorhabditis elegans as a good plants model system and so I will focus on plants. -
Interpreting the History of Evolutionary Biology Through a Kuhnian Prism: Sense Or Nonsense?
Interpreting the History of Evolutionary Biology through a Kuhnian Prism: Sense or Nonsense? Koen B. Tanghe Department of Philosophy and Moral Sciences, Universiteit Gent, Belgium Lieven Pauwels Department of Criminology, Criminal Law and Social Law, Universiteit Gent, Belgium Alexis De Tiège Department of Philosophy and Moral Sciences, Universiteit Gent, Belgium Johan Braeckman Department of Philosophy and Moral Sciences, Universiteit Gent, Belgium Traditionally, Thomas S. Kuhn’s The Structure of Scientific Revolutions (1962) is largely identified with his analysis of the structure of scientific revo- lutions. Here, we contribute to a minority tradition in the Kuhn literature by interpreting the history of evolutionary biology through the prism of the entire historical developmental model of sciences that he elaborates in The Structure. This research not only reveals a certain match between this model and the history of evolutionary biology but, more importantly, also sheds new light on several episodes in that history, and particularly on the publication of Charles Darwin’s On the Origin of Species (1859), the construction of the modern evolutionary synthesis, the chronic discontent with it, and the latest expression of that discon- tent, called the extended evolutionary synthesis. Lastly, we also explain why this kind of analysis hasn’t been done before. We would like to thank two anonymous reviewers for their constructive review, as well as the editor Alex Levine. Perspectives on Science 2021, vol. 29, no. 1 © 2021 by The Massachusetts Institute of Technology https://doi.org/10.1162/posc_a_00359 1 Downloaded from http://www.mitpressjournals.org/doi/pdf/10.1162/posc_a_00359 by guest on 30 September 2021 2 Evolutionary Biology through a Kuhnian Prism 1. -
Introduction and Historical Perspective
Chapter 1 Introduction and Historical Perspective “ Nothing in biology makes sense except in the light of evolution. ” modified by the developmental history of the organism, Theodosius Dobzhansky its physiology – from cellular to systems levels – and by the social and physical environment. Finally, behaviors are shaped through evolutionary forces of natural selection OVERVIEW that optimize survival and reproduction ( Figure 1.1 ). Truly, the study of behavior provides us with a window through Behavioral genetics aims to understand the genetic which we can view much of biology. mechanisms that enable the nervous system to direct Understanding behaviors requires a multidisciplinary appropriate interactions between organisms and their perspective, with regulation of gene expression at its core. social and physical environments. Early scientific The emerging field of behavioral genetics is still taking explorations of animal behavior defined the fields shape and its boundaries are still being defined. Behavioral of experimental psychology and classical ethology. genetics has evolved through the merger of experimental Behavioral genetics has emerged as an interdisciplin- psychology and classical ethology with evolutionary biol- ary science at the interface of experimental psychology, ogy and genetics, and also incorporates aspects of neuro- classical ethology, genetics, and neuroscience. This science ( Figure 1.2 ). To gain a perspective on the current chapter provides a brief overview of the emergence of definition of this field, it is helpful -
A Short History of DNA Technology 1865 - Gregor Mendel the Father of Genetics
A Short History of DNA Technology 1865 - Gregor Mendel The Father of Genetics The Augustinian monastery in old Brno, Moravia 1865 - Gregor Mendel • Law of Segregation • Law of Independent Assortment • Law of Dominance 1865 1915 - T.H. Morgan Genetics of Drosophila • Short generation time • Easy to maintain • Only 4 pairs of chromosomes 1865 1915 - T.H. Morgan •Genes located on chromosomes •Sex-linked inheritance wild type mutant •Gene linkage 0 •Recombination long aristae short aristae •Genetic mapping gray black body 48.5 body (cross-over maps) 57.5 red eyes cinnabar eyes 67.0 normal wings vestigial wings 104.5 red eyes brown eyes 1865 1928 - Frederick Griffith “Rough” colonies “Smooth” colonies Transformation of Streptococcus pneumoniae Living Living Heat killed Heat killed S cells mixed S cells R cells S cells with living R cells capsule Living S cells in blood Bacterial sample from dead mouse Strain Injection Results 1865 Beadle & Tatum - 1941 One Gene - One Enzyme Hypothesis Neurospora crassa Ascus Ascospores placed X-rays Fruiting on complete body medium All grow Minimal + amino acids No growth Minimal Minimal + vitamins in mutants Fragments placed on minimal medium Minimal plus: Mutant deficient in enzyme that synthesizes arginine Cys Glu Arg Lys His 1865 Beadle & Tatum - 1941 Gene A Gene B Gene C Minimal Medium + Citruline + Arginine + Ornithine Wild type PrecursorEnz A OrnithineEnz B CitrulineEnz C Arginine Metabolic block Class I Precursor OrnithineEnz B CitrulineEnz C Arginine Mutants Class II Mutants PrecursorEnz A Ornithine -
DNA: the Timeline and Evidence of Discovery
1/19/2017 DNA: The Timeline and Evidence of Discovery Interactive Click and Learn (Ann Brokaw Rocky River High School) Introduction For almost a century, many scientists paved the way to the ultimate discovery of DNA and its double helix structure. Without the work of these pioneering scientists, Watson and Crick may never have made their ground-breaking double helix model, published in 1953. The knowledge of how genetic material is stored and copied in this molecule gave rise to a new way of looking at and manipulating biological processes, called molecular biology. The breakthrough changed the face of biology and our lives forever. Watch The Double Helix short film (approximately 15 minutes) – hyperlinked here. 1 1/19/2017 1865 The Garden Pea 1865 The Garden Pea In 1865, Gregor Mendel established the foundation of genetics by unraveling the basic principles of heredity, though his work would not be recognized as “revolutionary” until after his death. By studying the common garden pea plant, Mendel demonstrated the inheritance of “discrete units” and introduced the idea that the inheritance of these units from generation to generation follows particular patterns. These patterns are now referred to as the “Laws of Mendelian Inheritance.” 2 1/19/2017 1869 The Isolation of “Nuclein” 1869 Isolated Nuclein Friedrich Miescher, a Swiss researcher, noticed an unknown precipitate in his work with white blood cells. Upon isolating the material, he noted that it resisted protein-digesting enzymes. Why is it important that the material was not digested by the enzymes? Further work led him to the discovery that the substance contained carbon, hydrogen, nitrogen and large amounts of phosphorus with no sulfur. -
Goings on in Mendel's Garden
40 Evolutionary Anthropology CROTCHETS & QUIDDITIES Goings on in Mendel’s Garden KENNETH WEISS The honorable monk probably didn’t cheat. But he led us astray in other ways. Gregor Mendel gave us the tools by discussed. But this may have inadver- which to do modern genetics, and we tently led us astray, in ways for which have a century of progress to show for we are paying a price today. The arti- it. We properly credit Mendel and his ficial nature of his experiments lured peas for showing us the particulate us into confusing the inheritance of nature of inheritance, but his work traits with the inheritance of genes. both enabled and disabled evolution- And this in turn has led to an unwar- ary thinking for several decades after ranted phenogenetic (see Note 1) de- its rediscovery. Since the factors he terminism that impairs our under- studied didn’t change over genera- standing of biology. tions, Mendel’s discoveries solved the problem that perplexed Darwin, that BLENDING IN blending inheritance would swamp variation and prevent evolution from Mendel wasn’t trying to explain evo- happening. Yet, for the same reason, lution. He knew of traits that varied Mendel’s work impeded evolutionary continuously in his experimental pea thought because evolution requires species, Pisum sativum, and appeared Figure 1. Mendel. change, and discrete variation was to blend in darwinian fashion from also incompatible with darwinian one generation to the next. But he gradualism. Eventually things were wanted to breed agriculturally valu- worked out, we got our unified theory able strains, so he avoided such traits used pea strains that differed only by (the neodarwinian Synthesis), and it and instead selected strains of pea the single traits he reported for each rested on Mendel’s discoveries. -
Eduard Fenzls Anteil
MARIA PETZ-GRABENBAUER ZUM LEBENSWERK VON EDUARD FENZL. DER BOTANISCHE GARTEN DER UNIVERSITÄT WIEN UND FENZLS BEITRAG AN DEN „GENERA PLANTARUM SECUNDUM ORDINES NATURALES DISPOSITA“ Ein gemeinsamer Weg „Vor allem muss man den Scharfsinn bewundern, mit dem es Fenzl gelingt, grössere Gruppen natürlich zu umgrenzen oder für zweifelhafte Gattungen den geeignetsten Platz im Systeme zu ermitteln. In dieser Beziehung sind die in Endlicher’s Generibus plantarum und in Ledebour’s Flora rossica bearbeiteten Familien als wahre Muster anzusehen. Hierin ist Fenzl mit Endlicher auf das Innigste verwandt; in der Beschrei- bung der einzelnen Arten übertrifft er ihn weit. Denn in dieser Richtung gebührt Fenzl das große Verdienst, dass er vorzüglich die organografisch und biologisch wichtigen Momente berücksichtigte und sich nicht bloß wie seine Vorgänger mit der Angabe der relativen Verhältnisse der einzelnen Theile begnügte, sondern sehr genaue absolute Messungen gebrauchte. So gelingt es ihm, einerseits seinen Beschreibungen eine große Genauigkeit zu verleihen, andererseits die von ihm aufgestellten Arten glücklich und natürlich zu begrenzen, so dass er stets die richtige Mitte zwischen zu großer Zer- splitterung in viele Arten, und den Vereinen von zu heterogenen Formen hält“.1 Mehr als 150 Jahre weitgehend unbeachtet blieben diese Ausführungen des Bota- nikers Heinrich Wilhelm Reichardt über den Anteil Eduard Fenzls an den „Genera plantarum secundum ordines naturales disposita“, die zwischen 1836 und 1840 von Stephan Ladislaus Endlicher veröffentlicht wurde. Mit diesem Werk gelang es Endli- cher neun Jahre vor seinem Tod, eine Übersicht des Pflanzenreiches herauszugeben, wie es seit den Arbeiten der Familie Jussieu Mitte des 18. Jahrhunderts nicht wieder versucht worden war. -
INTRODUCTION to GENETICS Table of Contents Heredity, Historical
INTRODUCTION TO GENETICS Table of Contents Heredity, historical perspectives | The Monk and his peas | Principle of segregation Dihybrid Crosses | Mutations | Genetic Terms | Links Heredity, Historical Perspective | Back to Top For much of human history people were unaware of the scientific details of how babies were conceived and how heredity worked. Clearly they were conceived, and clearly there was some hereditary connection between parents and children, but the mechanisms were not readily apparent. The Greek philosophers had a variety of ideas: Theophrastus proposed that male flowers caused female flowers to ripen; Hippocrates speculated that "seeds" were produced by various body parts and transmitted to offspring at the time of conception, and Aristotle thought that male and female semen mixed at conception. Aeschylus, in 458 BC, proposed the male as the parent, with the female as a "nurse for the young life sown within her". During the 1700s, Dutch microscopist Anton van Leeuwenhoek (1632-1723) discovered "animalcules" in the sperm of humans and other animals. Some scientists speculated they saw a "little man" (homunculus) inside each sperm. These scientists formed a school of thought known as the "spermists". They contended the only contributions of the female to the next generation were the womb in which the homunculus grew, and prenatal influences of the womb. An opposing school of thought, the ovists, believed that the future human was in the egg, and that sperm merely stimulated the growth of the egg. Ovists thought women carried eggs containing boy and girl children, and that the gender of the offspring was determined well before conception. -
Origins of the Myth of Social Darwinism: the Ambiguous Legacy of Richard Hofstadter’S Social Darwinism in American Thought
Journal of Economic Behavior & Organization 71 (2009) 37–51 Contents lists available at ScienceDirect Journal of Economic Behavior & Organization journal homepage: www.elsevier.com/locate/jebo Origins of the myth of social Darwinism: The ambiguous legacy of Richard Hofstadter’s Social Darwinism in American Thought Thomas C. Leonard Department of Economics, Princeton University, Fisher Hall, Princeton, NJ 08544, United States article info abstract Article history: The term “social Darwinism” owes its currency and many of its connotations to Richard Received 19 February 2007 Hofstadter’s influential Social Darwinism in American Thought, 1860–1915 (SDAT). The post- Accepted 8 November 2007 SDAT meanings of “social Darwinism” are the product of an unresolved Whiggish tension in Available online 6 March 2009 SDAT: Hofstadter championed economic reform over free markets, but he also condemned biology in social science, this while many progressive social scientists surveyed in SDAT JEL classification: offered biological justifications for economic reform. As a consequence, there are, in effect, B15 B31 two Hofstadters in SDAT. The first (call him Hofstadter1) disparaged as “social Darwinism” B12 biological justification of laissez-faire, for this was, in his view, doubly wrong. The sec- ond Hofstadter (call him Hofstadter2) documented, however incompletely, the underside Keywords: of progressive reform: racism, eugenics and imperialism, and even devised a term for it, Social Darwinism “Darwinian collectivism.” This essay documents and explains Hofstadter’s ambivalence in Evolution SDAT, especially where, as with Progressive Era eugenics, the “two Hofstadters” were at odds Progressive Era economics Malthus with each other. It explores the historiographic and semantic consequences of Hofstadter’s ambivalence, including its connection with the Left’s longstanding mistrust of Darwinism as apology for Malthusian political economy. -
Darwin's Influence on Mendel: Evidence from a New Translation Of
| PERSPECTIVES Darwin’sInfluence on Mendel: Evidence from a New Translation of Mendel’s Paper Daniel J. Fairbanks*,1 and Scott Abbott† *Department of Biology and †Department of Integrated Studies, Utah Valley University, Orem, Utah 84058 ORCID ID: 0000-0001-7422-0549 (D.J.F.) ABSTRACT Gregor Mendel’s classic paper, Versuche über Pflanzen-Hybriden (Experiments on Plant Hybrids), was published in 1866, hence 2016 is its sesquicentennial. Mendel completed his experiments in 1863 and shortly thereafter began compiling the results and writing his paper, which he presented in meetings of the Natural Science Society in Brünn in February and March of 1865. Mendel owned a personal copy of Darwin’s Origin of Species, a German translation published in 1863, and it contains his marginalia. Its publication date indicates that Mendel’s study of Darwin’s book could have had no influence while he was conducting his experiments but its publication date coincided with the period of time when he was preparing his paper, making it possible that Darwin’s writings influenced Mendel’s interpretations and theory. Based on this premise, we prepared a Darwinized English translation of Mendel’s paper by comparing German terms Mendel employed with the same terms in the German translation of Origin of Species in his possession, then using Darwin’s counterpart English words and phrases as much as possible in our translation. We found a substantially higher use of these terms in the final two (10th and 11th) sections of Mendel’s paper, particularly in one key paragraph, where Mendel reflects on evolutionary issues, providing strong evidence of Darwin’sinfluence on Mendel. -
Darwinism and the Law: Can Non-Naturalistic Scientific Theories Survive Constitutional Challenge?
DARWINISM AND THE LAW: CAN NON-NATURALISTIC SCIENTIFIC THEORIES SURVIVE CONSTITUTIONAL CHALLENGE? H. Wayne House* The entrance of Charles Darwin’s1 The Origin of Species2 changed the world. This is not because belief in evolution was a new and exciting theory unconsidered before this time, for indeed a variation of the view existed in many ancient cultures.3 In addition, several scientists already *H. Wayne House is distinguished professor of biblical studies and apologetics at Faith Seminary, Tacoma, WA, and a professor of law at Trinity Law School, California campus, of Trinity International University. He holds a J.D. from Regent University School of Law; Th.D., Concordia Seminary, St. Louis; M.Div., Th.M., Western Seminary; M.A., Abilene Christian University; B.A., Hardin-Simmons University. He has published over twenty books and scores of articles in the subjects of theology, law and ethics. I wish to thank James Stambaugh, librarian at Michigan Theological Seminary, for providing documentation. Also much appreciation to Eddie Colanter, Eric Rice, and Sean Choi, for their assistance in checking footnotes and/or providing sources for this article. 1 Charles Robert Darwin (1809-1882) was a British scientist who laid the foundation for modern evolutionary theory through his concept of the development of all forms of life through the gradual process of natural selection. He was born in Shrewsbury, Shropshire, England on February 12, 1809. Darwin originally went to study medicine at the University of Edinburgh but then dropped out in 1827 to prepare for becoming a clergyman in the Church of England by studying at the University of Cambridge.