The National Oral Health Research Initiative (Nohri)

Total Page:16

File Type:pdf, Size:1020Kb

The National Oral Health Research Initiative (Nohri) THE NATIONAL ORAL HEALTH RESEARCH INITIATIVE (NOHRI) The National Oral Health Research Conference 2008 organised by the Oral Health Division, Ministry of Health Malaysia, identified the need to establish a multiagency initiative to identify oral health research priorities for the country and to better manage the oral health research agenda in the country. The establishment of the National Health Research Initiative (NOHRI) in the 10th Malaysia Plan (10 MP) was mooted by the Oral Health Division in 2010 towards enhancing evidence-based policy decisions in the oral healthcare delivery system in the country. Stakeholders with oral health research interests from various organisations in the country which are currently represented in NOHRI are as follows: Oral Health Division, Ministry of Health Malaysia Faculty of Dentistry, University of Malaya (UM) Faculty of Dentistry, National University of Malaysia (UKM) Faculty of Dentistry, Science University of Malaysia (USM) Faculty of Dentistry, International Islamic University of Malaysia (UIAM) Faculty of Dentistry, Islamic Science University of Malaysia (USIM) Faculty of Dentistry, Mara University of Technology (UiTM) Faculty of Dentistry, International University of Malaysia (IMU) Faculty of Dentistry, Asian Institute of Medicine, Science & Technology (AIMST) Faculty of Dentistry, Malaysia Allied Health Science Academy (MAHSA) Dental Corp, Ministry of Defence Oral Cancer Research and Coordinating Centre, University Malaya (OCRCC) Malaysian Dental Association (MDA) The establishment of NOHRI is timely to better manage the oral health research agenda in the country in the following ways: Oral health research priorities of relevant stakeholders in oral health in the country are identified and collated. These priorities will be taken into consideration in the national health research priority setting. A mechanism that support collaboration for oral health research. Better bargaining power for research funds for oral health research initiatives. A national database on oral health research priorities in line with 5-year Malaysia Plans for monitoring the status of uptake and conduct of identified oral health research needs. This database will be updated annually. A compilation of oral health research abstracts to facilitate sharing of research findings. The facilitation of selection of oral health research projects that reflect local and national needs for training undergraduate and postgraduate students. PROPOSED ORAL HEALTH RESEARCH PRIORITIES FOR PERIOD 2011-2015 A B C D E F National Problems No. Group What do you need to know? Gaps & Needs Suggested Research (Document referred Research Scope Expected Output (Purpose/Objectives) (Rationale) Areas to) 1 Burden of Oral 1. Prevalence of oral disease 1. To determine the prevalence 1.High caries 1. Epidemiological 1. Burden of oral 1,2 Disease Disease/Condition and their contributory factors, of oral disease/conditions and prevalence 5-year studies for dental diseases and load of illness, risk factors to to identify contributory factors. olds: 76.2 % (2005), caries for evidence treatment needs oral disease and health seeking 87.1% (1995) to support policy 2. Risk factors behaviors 2.To determine the relationship change. to oral diseases between amount of smoking and 2.Special needs 3. Identification of 2. Predictors for caries risk caries risk children: Caries 2. Identify barriers to care amongst at risk population prevalence 78.2 % markers for caries 4. Data for oral groups 3.Predictors for caries risk (2008) risk assessment healthcare amongst at risk among risk groups financing population groups 2 Burden of Community Oral 1.Impact of community oral 1. Prevalence of enamel 1. Continuing 1. Epidemiological 1.Monitoring data Disease Health health intervention measures opacities among schoolchildren monitoring of Study on enamel 3,4 Interventions prevalence of enamel opacities on 2. Fluoride content of opacities (last done target groups. alternative sources of drinking in 2001) among 16- water. year old school children is needed to support the existing programme 2. Data on 2.Surveilance Study 2.Fluoride content fluoride content of in bottled drinking alternative sources /mineral of drinking water is water/reverse needed for informed osmosis drinking choices of drinking water. water. (A study in Sabah has shown variation in fluoride levels of bottled mineral water). Document updated_12 May 2011 PROPOSED ORAL HEALTH RESEARCH PRIORITIES FOR PERIOD 2011-2015 A B C D E F National Problems No. Group What do you need to know? Gaps & Needs Suggested Research (Document referred Research Scope Expected Output (Purpose/Objectives) (Rationale) Areas to) 3. Burden of Late detection To assess level of awareness To undertake multi-centre, 1. Oral cancer in Epidemiological 1. Increased Disease (Stage III & IV) of on characteristics and risk hospital and community-based Stages III & IV: 58.7% studies on success of awareness, early oral cancer, high factors of oral cancer among case-control, epidemiological different awareness detection and prevalence among the public; to determine and molecular studies on oral 2. High programs; changes higher survival 5 Indians nutritional intake and well- cancer patients on: prevalence among in nutrient intake 2. Data on rd th Increasing case being of oral cancer patients; 1. Mouth cancer awareness Indians: 3 and 7 among cancer effect of among young people to evaluate the diagnostic 2. Nutritional intake most common cancer patients; disease/ 6 with no habit value of detection tools for 3. Diagnostic tools for early intervention for treatment on Dietary nutrient early detection; to identify detection 3. Young people potentially malignant nutritional intake is significantly biomarkers significant in oral 4. Molecular biomarkers without habit having disorders and oral status, leading lower among oral cancers; to develop new anti- 5. Anti-cancer drug oral cancer: 8.3% cancer; evaluation of to formulation 7,8 cancer cases cancer drug against oral cancer effectiveness of of policies for 4. Lack of data different diagnostic general well- on effect of tools for early being of patients disease/treatment detection; molecular 3. Identificatio on nutritional status studies on n of biomarkers identification of and development potential biomarkers of anti-cancer and anti-cancer drugs drug for oral cancer Document updated_12 May 2011 PROPOSED ORAL HEALTH RESEARCH PRIORITIES FOR PERIOD 2011-2015 A B C D E F National Problems No. Group What do you need to know? Gaps & Needs Suggested Research (Document referred Research Scope Expected Output (Purpose/Objectives) (Rationale) Areas to) 4. Health Systems The need to develop Evidence and data for 1.Cost analysis, cost benefit 1.Limited costing data 1.Cost analysis, cost 1.Cost analysis a package for oral construct of package and cost effectiveness analysis on delivery of oral benefit and cost data to be used in healthcare in 1Care. of oral healthcare health care effectiveness analysis budgeting and interventions, Costing studies of oral healthcare oral health care of dental procedures and cost 2.Limited data on out- interventions, planning, relative per patient/attendance for of-pocket expenditure values of costs of primary and specialist care for oral healthcare 2.Costing studies of dental dental procedures procedures and 2.Econometric modeling for a 3.Lack of statistics to and cost per reimbursements basic oral healthcare package; model a basic oral patient/attendance in oral healthcare weighted capitation studies healthcare package. for primary and financing. specialist care 2.Data is useful 3.Econometric for working out modeling for a basic oral healthcare oral healthcare packages. package; weighted capitation studies Basic package that will ensure the coverage of the poorer segments of the population 5. Health Systems The need to Health seeking behaviors and Evaluation of dental services - Limited dental care 1.Oral Health Seeking Improvement and strengthen oral barriers to care focus on accessibility and services for adults Behaviors of Adults expansion of healthcare services utilization of services by adults. and concern about 2.Utilization of oral dental services for adults in Malaysia Look at current adults services, dental health of healthcare by adults especially for barriers, manpower needs. adults as they age. 3.Barriers of oral adults without healthcare amongst compromising adults current services for children. Document updated_12 May 2011 PROPOSED ORAL HEALTH RESEARCH PRIORITIES FOR PERIOD 2011-2015 A B C D E F National Problems Group What do you need to know? Gaps & Needs Suggested Research (Document referred Research Scope Expected Output (Purpose/Objectives) (Rationale) Areas to) 6. Health Systems Limited data on oral Oral health status and Health Needs Assessment Limited data on oral Studies on oral Useful data for health status and treatment needs of population health status and health status and planning oral treatment needs of with special needs, elderly and treatment needs of treatment needs of healthcare population with indigenous populations of population with population with marginalized and special needs, elderly Sabah and Sarawak. special needs, elderly special needs, elderly underserved and indigenous and indigenous and indigenous population groups. populations of Sabah populations of Sabah populations of Sabah and Sarawak. and Sarawak. and Sarawak. 7. H ealth Systems Evidence is needed Gains on population health as a Oral health policy research
Recommended publications
  • The Role of Alpha V Beta 6 Integrin in Enamel Biomineralization
    The Role of Alpha v Beta 6 Integrin in Enamel Biomineralization by Leila Mohazab A THESIS SUBMITTED IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF MASTERS OF SCIENCE in The Faculty of Graduate and Postdoctoral Studies (Craniofacial Science) THE UNIVERSITY OF BRITISH COLUMBIA (Vancouver) October 2013 ⃝c Leila Mohazab 2013 Abstract Tooth enamel has the highest degree of biomineralization of all vertebrate hard tissues. During the secretory stage of enamel formation, ameloblasts deposit an extracellular matrix that is in direct contact with ameloblast plasma membrane. Although it is known that integrins mediate cell-matrix adhesion and regulate cell signaling in most cell types, the receptors that reg- ulate ameloblast adhesion and matrix production are not well characterized. Thus, we hypothesized that αvβ6 integrin is expressed in ameloblasts where it regulates biomineralization of enamel. Human and mouse ameloblasts were found to express both β6 integrin mRNA and protein. The maxil- lary incisors of Itgb6-/- mice lacked yellow pigment and their mandibular incisors appeared chalky and rounded. Molars of Itgb6-/- mice showed signs of reduced mineralization and severe attrition. The mineral-to-protein ra- tio in the incisors was significantly reduced in Itgb6-/- enamel, mimicking hypomineralized amelogenesis imperfecta. Interestingly, amelogenin-rich ex- tracellular matrix abnormally accumulated between the ameloblast layer of Itgb6-/- mouse incisors and the forming enamel surface, and also between ameloblasts. This accumulation was related to increased synthesis of amel- ogenin, rather than to reduced removal of the matrix proteins. This was confirmed in cultured ameloblast-like cells, which did not use αvβ6 integrin as an endocytosis receptor for amelogenins, although it participated in cell adhesion on this matrix indirectly via endogenously produced matrix pro- teins.
    [Show full text]
  • Free PDF Download
    Eur opean Rev iew for Med ical and Pharmacol ogical Sci ences 2014; 18: 440-444 Radiographic evaluation of the prevalence of enamel pearls in a sample adult dental population H. ÇOLAK, M.M. HAMIDI, R. UZGUR 1, E. ERCAN, M. TURKAL 1 Department of Restorative Dentistry, Kirikkale University School of Dentistry, Kirikkale, Turkey 1Department of Prosthodontics, Kirikkale University School of Dentistry, Kirikkale, Turkey Abstract. – AIM: Enamel pearls are a tooth One theory of the enamel pearl etiology is that anomaly that can act as contributing factors in the enamel pearls develop as a result of a localized development of periodontal disease. Studies that developmental activity of a remnant of Hertwig’s have addressed the prevalence of enamel pearls in epithelial root sheath which has remained adher - populations were scarce. The purpose of this study 5 was to evaluate the prevalence of enamel pearls in ent to the root surface during root development . the permanent dentition of Turkish dental patients It is believed that cells differentiate into function - by means of panoramic radiographs. ing ameloblasts and produce enamel deposits on PATIENTS AND METHODS: Panoramic radi - the root. The conditions needed for local differ - ographs of 6912 patients were examined for the entiation and functioning of ameloblasts in this presence of enamel pearls. All data (age, sex and ectopic position are not fully understood 6,7 . systemic disease or syndrome) were obtained from the patient files and analyzed for enamel The most common site for enamel pearls is at pearls. Descriptive characteristics of sexes, the cementoenamel junction of multirooted jaws, and dental localization were recorded.
    [Show full text]
  • Supernumerary Teeth)
    Lecture 7 Paediatric Dentistry Dr. Israa Ali “Dental Anomalies” Dental anomalies are malformations or defects affecting teeth. They usually result from either disturbances to teeth development or they could be as result of environmental influences on teeth. Dental anomalies Developmental Environmental Defects in Effects on teeth number tooth structure Defects in Effects on teeth size tooth color Defects in Effects on teeth shape eruption Defects in teeth structure 11/04/2019 1 Developmental anomalies of dentition: Anomalies Anomalies Anomalies Anomalies of of number of size of shape structure Gemination Ameloenesis Hypodontia Fusion Imperfecta (AI) Microdontia Concrescence Accessory cusps Dentinoenesis Oliodontia Imperfecta (DI) Dens invaginatus Ectopic enamel Anodontia Dentin dysplasia Taurodontism Macrodontia Hypercementosis Accessory roots Regional Hyperdontia Odontodysplasia Dilaceration Developmental anomalies in the number of teeth: 1- Hypodontia: It is agenesis of some teeth (fewer than 6 teeth, not including the third molars). It can occur alone (isolated) or it could be associated with syndromes such as Down’s syndrome. It is uncommon in primary teeth. However, the permanent teeth are more likely to be affected with the most commonly affected teeth to be the third molars followed by mandibular second premolars, maxillary lateral incisors, maxillary second premolars, and mandibular central incisors. 2- Oligodontia: It is a term used to describe the developmental absence of more than six permanent teeth. It is also uncommon in primary teeth; and when the permanent 11/04/2019 2 teeth are affected, collapse of the dental arch and drifting of the few present teeth will result due to presence of excess space. Treatment of both hypodontia and oligodontia involve prosthodontic and orthodontic rehabilitation.
    [Show full text]
  • Day 2 Unicorn 1
    MasterDay2 A word from the author: MasterRQs and MasterDay2 are helpful only once you have basic knowledge of your subjects. Both of these files have the best and compile almost all radiographic images and cases available online. Extensive image coverage of each of topic has been done. Day 2 tests your basic knowledge of the subjects. I sincerely advise you to go through the mentioned topics properly- as the cases are mostly focussed on these. Know these diseases and medicines used, contraindications of them and MOA. What to note/write on the paper provided in the exam ? You will be given 2 sheets to write on/if anything. Here is what you need to write. Draw a line in the centre of the first page, and write Generic name on one side and Trade name on another. During the exam in the first 4-5 cases they mention you both the class/Drug/generic name and the trade name eg : Generic Trade Alendronate (Bisphosphonates) Fosamax Ethambutol (Anti TB) Abitol Zoledronic acid(Bisphosphonates) Reclast By the time you are done with 4-5 cases they will skip the Generic names in few questions because they presume you should know them as they have been mentioned in the exam only. So If you are unaware of this, you will have to go back and look for the important information again question by question, but if u have made this small chart, it saves your time! Must read topics 1. Hypertension and management 2. Myocardial infarction 3. Stroke 4. Diabetes 5. Syncope 6.
    [Show full text]
  • Enamel Pearl Associated with Localized Periodontitis in Hellenistic Age Woman
    T o m o v e t a l . C A S E R E P O R T Enamel pearl associated with localized periodontitis in Hellenistic age woman • Georgi Tomov (1), Elka Popova (2), Rumen Ivanov (3), Nadezhda Atanassova (4) • 1 - Оral Pathology Department, Faculty of Dental Medicine, Medical University, Plovdiv, Bulgaria 2 - Periodontology Department, Faculty of Dental Medicine, Medical University, Plovdiv, Bulgaria 3 - Archeologist 4 – National Anthropological Museum at Institute of Experimental Morphology, Pathology and Anthropology with Museum Address for correspondence: Assoc.Prof. Georgi Tomov, PhD Medical University Plovdiv, Faculty of Dental Medicine, Oral Pathology Department, Plovdiv, Bulgaria Phone: +359896742065 E- mail: [email protected] Bull Int Assoc Paleodont. 2017;11(2):62-66. Abstract Tooth anatomic factors like ectopic enamel pearls are often associated with localized periodontal inflammation and bone loss. There are no existing paleopathological data for such structural anomalies in ancient populations associated with periodontal pathology in the literature. A rare case of enamel pearl on the maxillary right first molar of women associated with localized periodontitis is presented and discussed. Keywords: enamel pearl; localized periodontitis; paleopathology; Hellenistic age Bull Int Assoc Paleodont. Volume 11, Number 2, 2017 www.paleodontology.com 62 Bulletin of the International Association for Paleodontology NO-FEE OPEN ACCESS JOURNAL T o m o v e t a l . C A S E R E P O R T Introduction are found in Plovdiv, Bulgaria (archeological site Bacterial plaque has been implicated as the “Kirkor Azarian” №4) and are provided for primary etiologic factor in the initiation and anthropological study in the Medical University progression of gingivitis and periodontitis (1).
    [Show full text]
  • Defects of Permanent Teeth
    ORAL PATHOLOGY Dr. Muna Lec.10 DEVELOPMENTAL DEFECTS OF THE ORAL AND MAXILLOFACIAL REGION 1- DEVELOPMENTAL DISORDERS OF TEETH. 2- DEVELOPMENTAL DEFECT OF THE ORAL MUCOSA. 3- DEVELOPMENTAL DEFECT OF THE TONGUE. 4- DEVELOPMENTAL DEFECT OF THE LIPS AND PALATE. 5- DEVELOPMENTAL DEFECT OF THE JAW BONES. 6- DEVELOPMENTAL CYST. 1- Developmental Disorders of Teeth Development of an ideal dentition depends on many factors:- • Formation of a full complement of teeth • Normal structural development of the dental tissues • Eruption of each group of teeth at the appropriate time into an adequate space • Eruption of teeth into correct relationship to occlude with their opposite numbers Developmental Alterations of Teeth 1- Developmental alteration in the size of teeth. 2- Developmental alteration in the number of teeth. 3- Developmental alteration in the shape of teeth. 4- Developmental alteration in the eruption of teeth. 5- Developmental alteration in the structure of teeth. 1- Alteration in size of teeth Microdontia Generalized microdontia: all teeth in the dentition appear smaller than normal, as in pituitary dwarfism Focal or localized microdontia: a single tooth is smaller than normal. The shape of these microdonts is also often altered with the reduced size. This phenomenon is most commonly seen with maxillary lateral incisors, in which the tooth crown appears cone or peg shaped, (peg lateral). Macrodontia Generalized macrodontia is characterized by the appearance of enlarged teeth throughout the dentition. This may be absolute, as seen in pituitary gigantism, or it may be relative owing to a disproportionately small maxilla and mandible. Focal, or localized, macrodontia: is characterized by an abnormally large tooth or group of teeth.
    [Show full text]
  • Bibliograficzne Z´Ro´Dła Ilustracji
    BIBLIOGRAFICZNE Z´RO´ DŁA ILUSTRACJI Dzięki uprzejmości: Acuson Computed Sonography Corporation, Mountain View, CA (Doppler ultrasonography). Zaczerpnięto z: Agur AMR, Lee M. Grant’s Atlas of Anatomy. 10th ed. Baltimore, MD: Lippincott Williams & Wilkins; 1999 (spinal column). Dzięki uprzejmości: Alzheimer’s Disease Education and Referral Center, a service of the National Institute on Aging (PET scan). Przedrukowano za zgodą: American Cancer Society, Inc. (malignant melanoma). Jennifer Anderson @ USDA-NRCS PLANTS Database (Podophyllum peltatum, Dicentra cucullaria). Zaczerpnięto z: Anderson SC, Poulsen K. Anderson’s Atlas of Hematology. Baltimore, MD: Lippincott Williams & Wilkins; 2003 (pronormoblast, basophilic normoblast, polychromatophilic normoblast, orthochromatophilic normoblast, reticulocyte, erythrocyte, plasmablast, proplasmacyte, plasma cells: plasmacytes, lymphoblast, lymphocyte, monoblast, premonocyte, monocyte, eosinophilic myelocyte, eosinophilic metamyelocyte, eosinophilic band, eosinophil, myeloblast, promyelocyte, neutrophilic myelocyte, neutrophilic metamyelocyte, neutrophilic band, neutrophil, basophilic myelocyte, basophilic metamyelocyte, basophilic band, basophil, megakaryoblast, promega- karyocyte, megakaryocyte, platelets, hypersegmentation, Pelger-Huët, Döhle body, Faggot cell, LE cell, cleaved cell, hairy cell, Dutcher body, Mott cell, Chédiak-Higashi granules, bilobed plasma cell, bacteria: spirochetes, stomatocytosis). Zaczerpnięto z: Baker CL. The Hughston Clinic Sports Medicine Book. 1st ed. Baltimore, MD:
    [Show full text]
  • Developmental Anomalies Affecting the Morphology of Teeth – a Review
    View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Portal de Periódicos da UNIVILLE (Universidade da Região de Joinville) ISSN: Electronic version: 1984-5685 RSBO. 2015 Jan-Mar;12(1):68-78 Literature Review Article Developmental anomalies affecting the morphology of teeth – a review Ashish Shrestha1 Vinay Marla1 Sushmita Shrestha2 Iccha K Maharjan3 Corresponding author: Ashish Shrestha Department of Oral Histology and Pathology, College of Dental Surgery B. P. Koirala Institute of Health Sciences Dharan – Sunsari – Nepal E-mail: [email protected] 1 Department of Oral Histology and Pathology, College of Dental Surgery, B. P. Koirala Institute of Health Sciences – Dharan – Nepal. 2 Department of Conservative Dentistry and Endodontics, College of Dental Surgery, B. P. Koirala Institute of Health Sciences – Dharan – Nepal. 3 Department of Oral Medicine and Radiology, College of Dental Surgery, B. P. Koirala Institute of Health Sciences – Dharan – Nepal. Received for publication: May 5, 2014. Accepted for publication: August 12, 2014. Abstract Keywords: developmental Introduction: The development of tooth is a complex process anomaly, diagnostic wherein there is series of interactions between the ectoderm and criteria, tooth ectomesenchyme. The role of genes in determining the shape and morphology. form of a specific tooth has already been defined, the alterations in which can lead to a variety of anomalies in regards to number, size, form, shape, structure, etc. Objective: To review the literature on the developmental anomalies of teeth. Literature review: The developmental anomalies affecting the morphology exists in both deciduous & permanent dentition and shows various forms such as gemination, fusion, concrescence, dilacerations, dens evaginatus, dens invaginatus, enamel pearls, taurodontism or peg laterals.
    [Show full text]
  • Role of Bmp2 in Dental Hard Tissue Formation
    Zurich Open Repository and Archive University of Zurich Main Library Strickhofstrasse 39 CH-8057 Zurich www.zora.uzh.ch Year: 2016 Role of Bmp2 in dental hard tissue formation Malik, Zeba Posted at the Zurich Open Repository and Archive, University of Zurich ZORA URL: https://doi.org/10.5167/uzh-204719 Dissertation Published Version Originally published at: Malik, Zeba. Role of Bmp2 in dental hard tissue formation. 2016, University of Zurich, Faculty of Science. Role of Bmp2 in Dental Hard Tissue Formation Dissertation (Juni 2016) zur Erlangung der naturwissenschaftlichen Doktorwürde (Dr.sc.nat) vorgelegt der Mathematisch-naturwissenschaftlichen Fakultät der Universität Zürich von Zeba Malik aus Indien Promotionkomitee Prof. Dr. Michael Hengartner Prof. Dr. Daniel Graf Prof. Dr. Lukas Sommer Dr. Aimee Zuniga Zurich 2016 1 Table of Contents 1. Summary .......................................................................................................................................................................... 4 2. Summary in German ................................................................................................................................................. 6 3. Introduction ..................................................................................................................................................................... 8 3.1 Bone morphogenetic proteins (Bmps) ............................................................................ 8 3.2 Tooth: Structure and Function .....................................................................................
    [Show full text]
  • Oral Pathology Disorders of Development of Teeth
    Oral Pathology DEVELOPMENTAL DEFECTS OF THE ORAL AND MAXILLOFACIAL REGION Developmental disturbances of the oral region are of these broad categories: (1) Developmental disturbances affecting teeth. (2) Developmental disturbances limited to soft tissue. (3) Developmental disturbances affecting bone. Disorders of development of teeth The development of teeth is regulated by genes, but the genetic program is very sensitive to disturbances in the environment such as infection, or toxic chemicals. The causes of developmental disorders of teeth are multifactorial, involving the interaction of genetic and environmental factors. These disorders may be prenatal or postnatal in origin and may inherit or acquired. Disorders of development of teeth may be due to abnormalities in the differentiation of the dental lamina and the tooth germs, causing anomalies number, size, form of teeth and abnormalities of morph differentiation or abnormalities in the formation of the dental hard tissue resulting in disturbances in tooth structure ((abnormalities of histo differentiation)). Developmental Alterations in the Number of Teeth Anodontia Absence of teeth is known as anodontia. This condition is further qualified as complete anodontia, when all teeth are missing; as partial anodontia or hypodontia, when one or several teeth are missing; as pseudoanodontia, when teeth are absent clinically because of impaction or delayed eruption; or as false anodontia, when teeth have been exfoliated or extracted. Partial anodontia is relatively common. Congenitally missing teeth are usually third molars, followed by second premolars and maxillary lateral incisors. 1-several regulatory genes are involved in tooth formation and development which may be mutated in hypodontia e.g. (MSX1 and Pax9). These genes are involved in the control of development of the face and of many other tissues and organs in the embryo.
    [Show full text]
  • PROGRAMMA DELL'insegnamento in Inglese
    PROGRAMMA DELL’INSEGNAMENTO in inglese I - ANATOMICAL-PATHOLOGY PROPEDEUTICS (Prof. G. Palmieri) - Definition and purpose of the discipline - Methodologies of histopathological investigation - Diagnostic limits of histopathology - Method of request for histopathological examination - Method of collection, storage and forwarding of the material to be examined - Evaluation and interpretation of the histopathological and cytopathological examination report and communication with the histopathologist II - ORAL PATHOLOGY (Prof. G. Palmieri) ANOMALIES OF OROFACIAL DEVELOPMENT Orofacial fissures, labial fasades (commissural and paramedian), double lip, Fordyce granules, language abnormalities (aglossia, microglossia, macroglossia, anchilogloxia, fixed language, language hairy, lingual thyroid), varicose veins, exostoses, bulls, Stafne defect, rare syndromes (hemi- hyperplasia, progressive facial atrophy, Crouzon syndrome, Apert syndrome, jaw-facial dysostosis). TOOTH ANOMALIES Developmental abnormalities due to environmental influences (enamel abnormalities, Turner's tooth, fluorosis, Luetic hypoplasia - Hutchinson's teeth and strawberry molar) Regressive alterations (friction, abrasion, erosion, abfractione), internal resorption and external, anomalies of coloring of the teeth (extrinsic and intrinsic). Localized disorders of the rash (primary impact, ankylosis) Congenital anomalies of the teeth: number (anodontia, hypodontia, oligodontia, hyperdontia), dimension (microdontia, macrodontia), of shape (gemination, fusion, with crescenza, cuspidi
    [Show full text]
  • Prevalence of Developmental Root Anomalies in an Indian Population
    Vol-7 Issue-3 2021 IJARIIE-ISSN(O)-2395-4396 PREVALENCE OF DEVELOPMENTAL ROOT ANOMALIES IN AN INDIAN POPULATION Nivetha G1, Caroline Jacob2 1Undergraduate student Saveetha Dental College, Saveetha Institute of Medical and Technical Science , Chennai,India. 2Senior Lecturer Department of Periodontics Saveetha Dental College, Saveetha Institute of Medical and Technical Science ,Chennai,India. Corresponding Author Dr.Caroline Jacob Abstract Introduction :Root anomalies such as labiogingival or palatogingival grooves as well as cervical enamel projections and enamel pearls may predispose teeth to periodontal disease as they are plaque retentive and difficult to instrument. Labiogingival and palatogingival grooves develop as a result of an infolding of the Hertwig's epithelial root sheath(HERS) in maxillary incisors while cervical enamel projections and enamel pearls are extensions of enamel found on the root surface predominantly in the furcation area of molars. These defects harbour plaque and lack of periodontal attachment predisposing the tooth to pulpitis or periodontal disease. Aim:To determine the prevalence of developmental root anomalies in extracted permanent incisors and molars. Materials and methods: 200 extracted human teeth comprising of central incisors(n=20), lateral incisors(n=20) and molars(n=160)observe the following anomalies : Labiogingival groove , Palatogingival groove, cervical enamel projection and enamel pearl using a pair of magnification loupes (2.5x). Labiogingival groove were investigated from labial ascept of central incisors. Palatogingival groove were investigated from palatal ascept of central incisors. Enamel pearls were observed for all the sample teeth while the cervical enamel projection were observed for the maxillary and mandibular molars. Results: It was observed that there was no prevalence of labiogingival groove which may be attributed to variation among races.
    [Show full text]