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Downloadable “I Hope You’Ll Do It the Same Way I’D Hope Truck Overnight May–June 2016 • Volume 37:3 Ev Cooper and the Conference that Didn’t Happen: Trials of an Early Freezing Page 14 The Technology of Revival, ISSN 1054-4305 Repair, and Rejuvenation Page 34 Interview with Robert A. Freitas $9.95 Page 43 Improve Your Odds of a Good Cryopreservation You have your cryonics funding and contracts in place but have you considered other steps you can take to prevent problems down the road? ü Keep Alcor up-to-date about personal and medical changes. ü Update your Alcor paperwork to reflect your current wishes. ü Execute a cryonics-friendly Living Will and Durable Power of Attorney for Health Care. ü Wear your bracelet and talk to your friends and family about your desire to be cryopreserved. ü Ask your relatives to sign Affidavits stating that they will not interfere with your cryopreservation. ü Attend local cryonics meetings or start a local group yourself. ü Contribute to Alcor’s operations and research. Contact Alcor (1-877-462-5267) and let us know how we can assist you. Visit the ALCOR FORUMS www.alcor.org/forums/ Discuss Alcor and cryonics topics with other members and Alcor officials. • The Alcor Foundation • Financial • Cell Repair Technologies • Rejuvenation • Cryobiology • Stabilization • Events and Meetings Other features include pseudonyms (pending verification of membership status) and a private forum. Visit the ALCOR BLOG www.alcor.org/blog/ Your source for news about: • Cryonics technology • Speaking events and meetings • Cryopreservation cases • Employment opportunities • Television programs about cryonics Alcor is on Facebook Connect with Alcor members and supporters on our official Facebook page: www.facebook.com/alcor.life.extension.foundation Become a fan and encourage interested friends, family members, and colleagues to support us too. COVER STORY: PAGE 14 Ev Cooper and the Conference that Didn’t Happen: Trials of an Early Freezing The earliest days of the cryonics movement, May–June 2016 • Volumee 37:3 before anyone was frozen, were a time Ev Cooper and the Conference that of hope and optimism untroubled by the Didn’t Happen: Trials of an Early Freezing problems of the technical requirements Page 14 of cryopreservation, including the cost and details of long-term storage. This “honeymoon” period came to an end as cryopreservations occurred that were not well- funded and had to depend on outside help from the cryonics community. The problems were particularly acute and soul-searching when someone well-known and well- respected experienced sudden arrest and very little funding was in place to carry out their The Technology of Revival, strongly expressed wish to be cryopreserved ISSN 1054-4305 Repair, and Rejuvenation for later revival. Such was the case of Marie Page 34 Phelps-Sweet, who was frozen in the summer Interview with Robert A. Freitas $9.95 Page 43 of 1967; its effects on the fledgling cryonics community are reported here. 34 The Technology of Revival, Repair, and Rejuvenation Part Four: Nanomedicine and Cryonics Cryonics is a concept in which people who are clinically dead are placed at liquid nitrogen temperature (-196 degrees Celsius) where they remain essentially unchanged. The assumption of cryonics is that these people can be revived, repaired, and rejuvenated by future scientific knowledge and procedures. In this multipart series York Porter reviews some of the proposals that have been made to try to solve the problem of revival, repair, and rejuvenation, including using nanotechnology as part of the effort. Various cell and tissue repair devices are discussed as well as a cryobiological view of the subject of repair after exposure to cryogenic temperatures. Part 4 of the series, included here, discusses the pioneering writings and research of Robert Freitas and the applications of nanomedicine for repair and rejuvenation of cryonics patients. 43 An Interview with Robert A. Freitas Cryonics magazine catches up with prolific nanotechnology writer Robert A. Freitas about the status of his nanomedicine books, recent developments in nanotechnology, and the applications of molecular nanotechnology to aging and the revival of cryonics patients. www.alcor.org Cryonics / May-June 2016 3 CONTENTS Editorial Board Saul Kent Ralph C. Merkle 5 QUOD INCEPIMUS CONFICIEMUS R. Michael Perry, Ph.D. How “Repair Denialism” Prevents a Rational Discussion About Cryonics Editor Since its inception, advocates of cryonics have persuasively argued Aschwin de Wolf that damage incurred during cryonics procedures is only an argument against cryonics if the brain in its damaged state cannot be restored to Contributing Writers its original state. Unfortunately, many (scientific) critics are not aware of Stephen Bridge this argument, or do not want to recognize it in public, which leads to a Aschwin de Wolf serious misunderstanding of the technical feasibility of cryonics. Martin Borch Jensen Ralph C. Merkle Max More 6 CEO Update R. Michael Perry, Ph.D. In his latest Update, Alcor CEO and President Max More reports on York W. Porter readiness, recent cases, and case report status. He also thanks long- Carrie Wong time Alcor staff member and paramedic Aaron Drake for his dedicated service to the organization as he transitions to a new role. A new analysis Copyright 2016 of Kim Suozzi’s CT scan reveals better cryoprotection and inhibition of by Alcor Life Extension Foundation ice formation than was assumed at the time of cryopreservation. Positive All rights reserved. media exposure of Alcor and cryonics is also covered. Reproduction, in whole or part, without permission is prohibited. 10 Why You Want to Read Alcor’s New Book Alcor’s new book, Preserving Minds, Saving Lives, is the most ambitious Cryonics magazine is published bi-monthly. collection of articles about cryonics and Alcor ever published. Read here To subscribe to the printed edition why you want to read this and give a copy to friends and relatives. and/or change your address, please call 480.905.1906 x101or visit the magazine 12 Dying Doesn’t Really Affect Overpopulation website: One of the most common objections to life extension and cryonics is www.alcor.org/magazine that it will lead to “overpopulation.” In this elegant article, Martin Borch Jensen shows that changes in birth rate have a much bigger impact in Please note: If you change your address less than population than people remaining alive. a month before the magazine is mailed, it may be sent to your old address. 30 An Introduction to CRISPR: Part 2 Address correspondence to: CRISPR (“clustered regularly interspaced short palindromic repeats”) Cryonics Magazine refers to the unique organization of short, repeated DNA sequences 7895 East Acoma Drive, Suite 110 found in the genomes of bacteria and other microorganisms. These Scottsdale, Arizona 85260 sequences are a vital component of the immune system of simple Phone: 480.905.1906 lifeforms. Very recently scientists have adapted CRISPR to target and Toll free: 877.462.5267 modify DNA with unprecedented accuracy. This new technology seems Fax: 480.922.9027 poised to achieve a breakthrough in treating genetic and viral diseases. Letters to the Editor welcome: 46 Membership Statistics [email protected] How many members, associate members, and patients does Alcor have and where do they live? Advertising inquiries: 480.905.1906 x113 [email protected] 47 Resuscitation Update ISSN: 1054-4305 Mike Perry surveys the news and research to report on new developments that bring us closer to the resuscitation of cryonics Visit us on the web at www.alcor.org patients. Alcor News Blog http://www.alcor.org/blog/ 4 Cryonics / May-June 2016 www.alcor.org Quod incepimus conficiemus Photo: Cryo-Care Equipment Corporation at 2340 E. Washington St., Phoenix, AZ. Dr. Bedford’s “home” in 1970 or 1971. HOW “Repair DENIALISm” PREVENTS A RationaL DISCUSSION ABOUT Cryonics By Aschwin de Wolf cientific critics of cryonics often advances of the future, including cell repair. detailed structural arguments, especially given do not seem to understand the Cryonics permits the use of an imperfect the fact that damage incurred during the Sbasics of cryobiology (freezing does preservation technique, provided that the cryopreservation process is also locked into not “burst” cells), or remain ignorant damage produced by sub-optimal technologies place by those same low temperatures. that cryopreservation without freezing does not exclude inferring the original state of One might object that the idea of cell (“vitrification”) has been a routine the brain (or body) from the damaged state. repair is itself implausible, i.e. that the laws procedure in cryonics since 2000. It is This is a subtle, but important, implication of of physics do not permit the idea of healing not surprising, then, that some advocates the idea of medical time travel. Pointing out at the molecular level. The problem with of cryonics question the integrity of such that existing cryopreservation techniques are this argument is that human biology already critics. Are they deliberately ignoring or imperfect does not refute the cryonics premise, features molecular assembly and DNA distorting the evidence that supports the unless it can be shown that such techniques repair. Whether one subscribes to the idea technical feasibility of cryonics? One Alcor produce information-theoretic death. of mechanical molecular nanotechnology, official has informally called such critics Not all injuries to the brain can be repaired. modification of viruses or white blood cells, “cryonics deniers.” One might object to For example, when the period of cerebral or further miniaturization of 3D printing, using such a strong characterization because ischemia is so extensive that bacteria-driven it is reasonable to assume that some kind of the feasibility of cryonics is a conjecture autolysis has erased most of the brain structure, nanomedicine will be developed in the future. not a fact. I would like to suggest a more meaningful restoration is not likely to be I once called the idea that human suspended specific kind of denial.
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