“Is Cryonics an Ethical Means of Life Extension?” Rebekah Cron University of Exeter 2014
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County of San Diego Department of the Medical Examiner 2016 Annual
County of San Diego Department of the Medical Examiner 2016 Annual Report Dr. Glenn Wagner Chief Medical Examiner 2016 ANNUAL REPORT SAN DIEGO COUNTY MEDICAL EXAMINER TABLE OF CONTENTS TABLE OF CONTENTS EXECUTIVE SUMMARY ......................................................................... 1 OVERVIEW AND INTRODUCTION ........................................................... 5 DEDICATION, MISSION, AND VISION .......................................................................... 7 POPULATION AND GEOGRAPHY OF SAN DIEGO COUNTY ............................................ 9 DEATHS WE INVESTIGATE ....................................................................................... 11 HISTORY ................................................................................................................. 13 ORGANIZATIONAL CHART ........................................................................................ 15 MEDICAL EXAMINER FACILITY ................................................................................. 17 HOURS AND LOCATION ........................................................................................... 19 ACTIVITIES OF THE MEDICAL EXAMINER .............................................. 21 INVESTIGATIONS ..................................................................................................... 23 AUTOPSIES ............................................................................................................. 25 EXAMINATION ROOM ............................................................................................ -
Piercing the Veil: the Limits of Brain Death As a Legal Fiction
University of Michigan Journal of Law Reform Volume 48 2015 Piercing the Veil: The Limits of Brain Death as a Legal Fiction Seema K. Shah Department of Bioethics, National Institutes of Health Follow this and additional works at: https://repository.law.umich.edu/mjlr Part of the Health Law and Policy Commons, and the Medical Jurisprudence Commons Recommended Citation Seema K. Shah, Piercing the Veil: The Limits of Brain Death as a Legal Fiction, 48 U. MICH. J. L. REFORM 301 (2015). Available at: https://repository.law.umich.edu/mjlr/vol48/iss2/1 This Article is brought to you for free and open access by the University of Michigan Journal of Law Reform at University of Michigan Law School Scholarship Repository. It has been accepted for inclusion in University of Michigan Journal of Law Reform by an authorized editor of University of Michigan Law School Scholarship Repository. For more information, please contact [email protected]. PIERCING THE VEIL: THE LIMITS OF BRAIN DEATH AS A LEGAL FICTION Seema K. Shah* Brain death is different from the traditional, biological conception of death. Al- though there is no possibility of a meaningful recovery, considerable scientific evidence shows that neurological and other functions persist in patients accurately diagnosed as brain dead. Elsewhere with others, I have argued that brain death should be understood as an unacknowledged status legal fiction. A legal fiction arises when the law treats something as true, though it is known to be false or not known to be true, for a particular legal purpose (like the fiction that corporations are persons). -
Eternity and Immortality in Spinoza's Ethics
Midwest Studies in Philosophy, XXVI (2002) Eternity and Immortality in Spinoza’s Ethics STEVEN NADLER I Descartes famously prided himself on the felicitous consequences of his philoso- phy for religion. In particular, he believed that by so separating the mind from the corruptible body, his radical substance dualism offered the best possible defense of and explanation for the immortality of the soul. “Our natural knowledge tells us that the mind is distinct from the body, and that it is a substance...And this entitles us to conclude that the mind, insofar as it can be known by natural phi- losophy, is immortal.”1 Though he cannot with certainty rule out the possibility that God has miraculously endowed the soul with “such a nature that its duration will come to an end simultaneously with the end of the body,” nonetheless, because the soul (unlike the human body, which is merely a collection of material parts) is a substance in its own right, and is not subject to the kind of decomposition to which the body is subject, it is by its nature immortal. When the body dies, the soul—which was only temporarily united with it—is to enjoy a separate existence. By contrast, Spinoza’s views on the immortality of the soul—like his views on many issues—are, at least in the eyes of most readers, notoriously difficult to fathom. One prominent scholar, in what seems to be a cry of frustration after having wrestled with the relevant propositions in Part Five of Ethics,claims that this part of the work is an “unmitigated and seemingly unmotivated disaster.. -
Therapeutic Targeting of Replicative Immortality
Seminars in Cancer Biology 35 (2015) S104–S128 Contents lists available at ScienceDirect Seminars in Cancer Biology jo urnal homepage: www.elsevier.com/locate/semcancer Review Therapeutic targeting of replicative immortality a,∗ b c d e Paul Yaswen , Karen L. MacKenzie , W. Nicol Keith , Patricia Hentosh , Francis Rodier , f g h i c Jiyue Zhu , Gary L. Firestone , Ander Matheu , Amancio Carnero , Alan Bilsland , j k,1 k,1 l,1 Tabetha Sundin , Kanya Honoki , Hiromasa Fujii , Alexandros G. Georgakilas , m,1 n,o,1 p,1 q,1 Amedeo Amedei , Amr Amin , Bill Helferich , Chandra S. Boosani , r,1 s,1 t,1 u,1 Gunjan Guha , Maria Rosa Ciriolo , Sophie Chen , Sulma I. Mohammed , v,1 r,1 w,1 m,1 Asfar S. Azmi , Dipita Bhakta , Dorota Halicka , Elena Niccolai , s,1 n,o,1 x,1 p,1 Katia Aquilano , S. Salman Ashraf , Somaira Nowsheen , Xujuan Yang a Life Sciences Division, Lawrence Berkeley National Lab, Berkeley, CA, United States b Children’s Cancer Institute Australia, Kensington, New South Wales, Australia c University of Glasgow, Glasgow, United Kingdom d Old Dominion University, Norfolk, VA, United States e Universit´e de Montr´eal, Montr´eal, QC, Canada f Washington State University College of Pharmacy, Pullman, WA, United States g University of California Berkeley, Berkeley, CA, United States h Biodonostia Institute, Gipuzkoa, Spain i Instituto de Biomedicina de Sevilla, HUVR, Consejo Superior de Investigaciones Cientificas, Universdad de Sevilla, Seville, Spain j Sentara Healthcare, Norfolk, VA, United States k Nara Medical University, Kashihara, -
Medical-Legal Aspects of Cryonics: Prospects for Immortality Ethical - Legal and Social Challenges to a Brave New World Genetics - Ethics and the Law
Journal of Contemporary Health Law & Policy (1985-2015) Volume 2 Issue 1 Article 13 1986 Medical-Legal Aspects of Cryonics: Prospects for Immortality Ethical - Legal and Social Challenges to a Brave New World Genetics - Ethics and the Law Harold A. Buetow Follow this and additional works at: https://scholarship.law.edu/jchlp Recommended Citation Harold A. Buetow, Medical-Legal Aspects of Cryonics: Prospects for Immortality Ethical - Legal and Social Challenges to a Brave New World Genetics - Ethics and the Law, 2 J. Contemp. Health L. & Pol'y 173 (1986). Available at: https://scholarship.law.edu/jchlp/vol2/iss1/13 This Book Review is brought to you for free and open access by CUA Law Scholarship Repository. It has been accepted for inclusion in Journal of Contemporary Health Law & Policy (1985-2015) by an authorized editor of CUA Law Scholarship Repository. For more information, please contact [email protected]. BOOK REVIEWS MEDICAL-LEGAL ASPECTS OF CRYONICS: PROSPECTS FOR IMMORTALITY. New York City: Associated Faculty Press 1983. Pp. 81. $12.00. ETHICAL, LEGAL AND SOCIAL CHALLENGES TO A BRAVE NEW WORLD. New York City: Associated Faculty Press 2 Vols. 1982. 1 Vol. Pp. 286, $32.00. 2 Vol. Pp. 264, $28.50. GENETICS, ETHICS AND THE LAW. By George P. Smith, II. New York City: Associated Faculty Press, 1981. Pp. 241. $28.50, cloth; $18.50, paper. Reviewed by Harold A. Buetow, M.A., Ph.D., J.D. In 1968, the University of Michigan Law Review published an article enti- tled, "Through A Test Tube Darkly: Artificial Insemination and The Law."' Its author was George P. -
Evidence-Based Policy Cause Area Report
Evidence-Based Policy Cause Area Report AUTHOR: 11/18 MARINELLA CAPRIATI, DPHIL 1 — Founders Pledge Animal Welfare Executive Summary By supporting increased use of evidence in the governments of low- and middle-income countries, donors can dramatically increase their impact on the lives of people living in poverty. This report explores how focusing on evidence-based policy provides an opportunity for leverage, and presents the most promising organisation we identified in this area. A high-risk/high-return opportunity for leverage In the 2013 report ‘The State of the Poor’, the World Bank reported that, as of 2010, roughly 83% of people in extreme poverty lived in countries classified as ‘lower-middle income’ or below. By far the most resources spent on tackling poverty come from local governments. American think tank the Brookings Institution found that, in 2011, $2.3 trillion of the $2.8 trillion spent on financing development came from domestic government revenues in the countries affected. There are often large differences in the effectiveness and cost-effectiveness of social programs— the amount of good done per dollar spent can vary significantly across programs. Employing evidence allows us to identify the most cost-effective social programs. This is useful information for donors choosing which charity to support, but also for governments choosing which programs to implement, and how. This suggests that employing philanthropic funding to improve the effectiveness of policymaking in low- and middle-income countries is likely to constitute an exceptional opportunity for leverage: by supporting the production and use of evidence in low- and middle-income countries, donors can potentially enable policy makers to implement more effective policies, thereby reaching many more people than direct interventions. -
9 Xenon Handling and Cryogenics
9 Xenon Handling and Cryogenics 9.1 Overview The Xe handling and cryogenics strategy of LZ derives strongly from the successful LUX program and takes maximum advantage of key technologies demonstrated there: chromatographic krypton removal, high-flow online purification, high-efficiency two-phase heat exchange, sensitive in situ monitoring of Xe purity, and thermosyphon cryogenics. In many cases, the primary technical challenge of the LZ implementation is how to best scale up from LUX. Two classes of impurities are of concern: electronegatives such as O2 and H2O that suppress charge and light transport in the TPC, and radioactive noble gases such as 85Kr, 39Ar, and 222Rn that create backgrounds that are not amenable to self-shielding. Both types of impurities may be found in the vendor- supplied Xe, and both may also be introduced into the detector during operations via outgassing and emanation. The purity goals are summarized in Table 9.1.1. We have three mitigation techniques to control these impurities. First, electronegatives are suppressed during operations by continuous circulation of the Xe in gaseous form through a hot (450 oC) zirconium getter. Gettering in the gas phase is made practical by a two-phase heat exchanger. A metal-diaphragm gas pump drives the circulation and the system is capable of purifying the entire Xe stockpile in 2.3 days. Second, the problematic radioactive species, 85Kr and 39Ar, which have relatively long half-lives (10.8 years and 269 years, respectively) and no supporting parents, can be removed from the vendor-supplied Xe prior to the start of operations. -
Immortality of the Soul (Plat Ōn) and Bodily Resurrection (Paul) — Any Rapprochement?
IMMORTALITY OF THE SOUL (PLAT ŌN) AND BODILY RESURRECTION (PAUL) — ANY RAPPROCHEMENT? ChrYs C. Caragounis [email protected] ABSTRACT It is a usual assumption among NeW Testament scholars that in his discussion of the resurrec - tion of the dead, Paul holds to the JeWish VieW of the resurrection of the bodY, not to the Hellenic (Platonic) VieW of the immortalitY of the soul. As this question impinges on the question of anthropologY, it is further stated that according to the Hellenic VieW man has a bodY — Which, moreoVer is conceiVed as a tomb of the soul (Orphics) — Whereas accor - ding to the JeWish VieW man is a bodY. A careful inVestigation of the Hellenic and OT-JeWish eVidence shoWs that it is a metho - dological miss to confuse VieWs in Hom ēros and the Orphics With later VieWs in Sokrates and Plat ōn. MoreoVer there neVer Was a “JeWish VieW” of the resurrection. There Were fiVe/siX VieWs. The resurrection of the bodY Was a minoritY VieW. The Pauline teXts shoW that Paul speaks of the resurrection of the dead but neVer of the resurrection of the bodY as Well as that man has a bodY. It is thus intriguing to compare Paul’s VieW of resurrection With Plat ōn’s VieW of the immortalitY of the soul and see hoW far apart theY are from one another. KEY WORDS : First Corinthians, Resurrection (of the bodY), ImmortalitY of the soul. 3 2 1 5 - 1. INTRODUCTION 3 2 . P P , Ernest Best prefaces his discussion of 1 Th 5:23 in his commentarY With 6 1 0 the remark that “To the Greek for Whom the bodY Was the tomb or prison of the 2 ; 1 7 immortal soul its ultimate fate Was unimportant” . -
Cryogenics in Space
— 37 — Cryogenics in space Nicola RandoI Abstract Cryogenics plays a key role on board space-science missions, with a range of applications, mainly in the domain of astrophysics. Indeed a tremendous progress has been achieved over the last 20 years in cryogenics, with enhanced reliability and simpler operations, thus matching the needs of advanced focal-plane detectors and complex science instrumentation. In this article we provide an overview of recent applications of cryogenics in space, with specific emphasis on science missions. The overview includes an analysis of the impact of cryogenics on the spacecraft system design and of the main technical solutions presently adopted. Critical technology developments and programmatic aspects are also addressed, including specific needs of future science missions and lessons learnt from recent programmes. Introduction H. Kamerlingh-Onnes liquefied 4He for the first time in 1908 and discovered superconductivity in 1911. About 100 years after such achievements (Pobell 1996), cryogenics plays a key role on board space-science missions, providing the environ- ment required to perform highly sensitive measurements by suppressing the thermal background radiation and allowing advantage to be taken of the performance of cryogenic detectors. In the last 20 years several spacecraft have been equipped with cryogenic in- strumentation. Among such missions we should mention IRAS (launched in 1983), ESA’s ISO (launched in 1995) (Kessler et al 1996) and, more recently, NASA’s Spitzer (formerly SIRTF, launched in 2006) (Werner 2005) and the Japanese mis- sion Akari (IR astronomy mission launched in 2006) (Shibai 2007). New missions involving cryogenics are the ESA missions Planck (dedicated to the mapping of the cosmic background radiation) and Herschel (far infrared and sub-millimetre observatory), carrying instruments operating at temperatures of 0.1 K and 0.3 K, respectively (Crone et al 2006). -
Cryogenics – the Basics Or Pre-Basics Lesson 1 D
Cryogenics – The Basics or Pre-Basics Lesson 1 D. Kashy Version 3 Lesson 1 - Objectives • Look at common liquids and gases to get a feeling for their properties • Look at Nitrogen and Helium • Discuss Pressure and Temperature Scales • Learn more about different phases of these fluids • Become familiar with some cryogenic fluids properties Liquids – Water (a good reference) H2O density is 1 g/cc 10cm Total weight 1000g or 1kg (2.2lbs) Cube of water – volume 1000cc = 1 liter Liquids – Motor Oil 10cm 15W30 density is 0.9 g/cc Total weight 900g or 0.9 kg (2lbs) Cube of motor oil – volume 1000cc = 1 liter Density can and usually does change with temperature 15W30 Oil Properties Density Curve Density scale Viscosity scale Viscosity Curve Water density vs temperature What happens here? What happens here? Note: This plot is for SATURATED Water – Discussed soon Water and Ice Water Phase Diagram Temperature and Pressure scales • Fahrenheit: 32F water freezes 212 water boils (at atmospheric pressure) • Celsius: 0C water freezes and 100C water boils (again at atmospheric pressure) • Kelvin: 273.15 water freezes and 373.15 water boils (0K is absolute zero – All motion would stop even electrons around a nucleus) • psi (pounds per square in) one can reference absolute pressure or “gage” pressure (psia or psig) • 14.7psia is one Atmosphere • 0 Atmosphere is absolute vacuum, and 0psia and -14.7psig • Standard Temperature and Pressure (STP) is 20C (68F) and 1 atm Temperature Scales Gases– Air Air density is 1.2kg/m3 => NO Kidding! 100cm =1m Total weight -
Cryogenicscryogenics Forfor Particleparticle Acceleratorsaccelerators Ph
CryogenicsCryogenics forfor particleparticle acceleratorsaccelerators Ph. Lebrun CAS Course in General Accelerator Physics Divonne-les-Bains, 23-27 February 2009 Contents • Low temperatures and liquefied gases • Cryogenics in accelerators • Properties of fluids • Heat transfer & thermal insulation • Cryogenic distribution & cooling schemes • Refrigeration & liquefaction Contents • Low temperatures and liquefied gases ••• CryogenicsCryogenicsCryogenics ininin acceleratorsacceleratorsaccelerators ••• PropertiesPropertiesProperties ofofof fluidsfluidsfluids ••• HeatHeatHeat transfertransfertransfer &&& thermalthermalthermal insulationinsulationinsulation ••• CryogenicCryogenicCryogenic distributiondistributiondistribution &&& coolingcoolingcooling schemesschemesschemes ••• RefrigerationRefrigerationRefrigeration &&& liquefactionliquefactionliquefaction • cryogenics, that branch of physics which deals with the production of very low temperatures and their effects on matter Oxford English Dictionary 2nd edition, Oxford University Press (1989) • cryogenics, the science and technology of temperatures below 120 K New International Dictionary of Refrigeration 3rd edition, IIF-IIR Paris (1975) Characteristic temperatures of cryogens Triple point Normal boiling Critical Cryogen [K] point [K] point [K] Methane 90.7 111.6 190.5 Oxygen 54.4 90.2 154.6 Argon 83.8 87.3 150.9 Nitrogen 63.1 77.3 126.2 Neon 24.6 27.1 44.4 Hydrogen 13.8 20.4 33.2 Helium 2.2 (*) 4.2 5.2 (*): λ Point Densification, liquefaction & separation of gases LNG Rocket fuels LIN & LOX 130 000 m3 LNG carrier with double hull Ariane 5 25 t LHY, 130 t LOX Air separation by cryogenic distillation Up to 4500 t/day LOX What is a low temperature? • The entropy of a thermodynamical system in a macrostate corresponding to a multiplicity W of microstates is S = kB ln W • Adding reversibly heat dQ to the system results in a change of its entropy dS with a proportionality factor T T = dQ/dS ⇒ high temperature: heating produces small entropy change ⇒ low temperature: heating produces large entropy change L. -
General Anesthesia and Altered States of Arousal: a Systems Neuroscience Analysis
General Anesthesia and Altered States of Arousal: A Systems Neuroscience Analysis The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Citation Brown, Emery N., Patrick L. Purdon, and Christa J. Van Dort. “General Anesthesia and Altered States of Arousal: A Systems Neuroscience Analysis.” Annual Review of Neuroscience 34, no. 1 (July 21, 2011): 601–628. As Published http://dx.doi.org/10.1146/annurev-neuro-060909-153200 Publisher Annual Reviews Version Author's final manuscript Citable link http://hdl.handle.net/1721.1/86331 Terms of Use Creative Commons Attribution-Noncommercial-Share Alike Detailed Terms http://creativecommons.org/licenses/by-nc-sa/4.0/ NIH Public Access Author Manuscript Annu Rev Neurosci. Author manuscript; available in PMC 2012 July 06. NIH-PA Author ManuscriptPublished NIH-PA Author Manuscript in final edited NIH-PA Author Manuscript form as: Annu Rev Neurosci. 2011 ; 34: 601–628. doi:10.1146/annurev-neuro-060909-153200. General Anesthesia and Altered States of Arousal: A Systems Neuroscience Analysis Emery N. Brown1,2,3, Patrick L. Purdon1,2, and Christa J. Van Dort1,2 Emery N. Brown: [email protected]; Patrick L. Purdon: [email protected]; Christa J. Van Dort: [email protected] 1Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114 2Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 3Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 Abstract Placing a patient in a state of general anesthesia is crucial for safely and humanely performing most surgical and many nonsurgical procedures.