Anti-PARP10 Antibody (ARG65760)

Product datasheet [email protected]

ARG65760 Package: 100 μl anti-PARP10 antibody Store at: -20°C

Summary

Product Description Rabbit Polyclonal antibody recognizes PARP10

Tested Reactivity Hu

Tested Application IHC-P

Host Rabbit

Clonality Polyclonal

Isotype IgG

Target Name PARP10

Antigen Species Human

Immunogen Synthetic peptide of Human PARP10

Conjugation Un-conjugated

Alternate Names ARTD10; PARP-10; ADP-ribosyltransferase diphtheria toxin-like 10; EC 2.4.2.30; Poly [ADP-ribose] polymerase 10

Application Instructions

Application table Application Dilution

IHC-P 1:50 - 1:200

Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Positive Control Human ovarian cancer and Human cervical cancer

Calculated Mw 110 kDa

Properties

Form Liquid

Purification Affinity purification with immunogen.

Buffer PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol

Preservative 0.05% Sodium azide

Stabilizer 40% Glycerol

Concentration 1.8 mg/ml

Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.

Note For laboratory research only, not for drug, diagnostic or other use. www.arigobio.com 1/2 Bioinformation

Database links GeneID: 84875 Human

Swiss-port # Q53GL7 Human

Gene Symbol PARP10

Gene Full Name poly (ADP-ribose) polymerase family, member 10

Background Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofactors (Yu et al., 2005 [PubMed 15674325]). [supplied by OMIM, Mar 2008]

Function May play a role in cell proliferation. May be required for the maintenance of cell cycle progression. [UniProt]

Images

ARG65760 anti-PARP10 antibody IHC-P image

Immunohistochemistry: paraffin-embedded Human ovarian cancer tissue stained with ARG65760 anti-PARP10 antibody (left) at 1:30 dilution, or the same antibody pre-incubated with antigen (right). (Original magnification: X200)

ARG65760 anti-PARP10 antibody IHC-P image

Immunohistochemistry: paraffin-embedded Human cervical cancer tissue stained with ARG65760 anti-PARP10 antibody (left) at 1:30 dilution, or the same antibody pre-incubated with antigen (right). (Original magnification: X200)