中文名称：雌二醇

英文名称：

化学名称：雌甾-1，3，5（10）-三烯-3,17β-二醇

分子式：C18H24O2·½H2O

分子量：281.4

CAS No：50-28-2

适应症：用于治疗雌激素缺乏综合征，包括预防有发生骨折危险妇女的骨矿物质含量的丢失。有完整子宫的妇女应同时使用对抗

治疗。

Estradiol Valerate EP Impurity F (17-Butyrate Estradiol-16,16,17-d3 Estradiol-d3 Glucuronide Estradiol) CAS No. 79073-37-9 C24H29O8D3 M.W. 451.54 CAS No. 18069-79-9 C18H21D3O2 M.W. 275.40 CBNE-1653 C22H30O3 M.W. 342.48 CBNE-16531 CBNE-16533

第 1 页 共 11 页 Estradiol-3-Glucuronide EP Impurity B 17-alpha-Ethynylestradiol-2,4,16,16-d4 CAS No. 15270-30-1 (3-Valerate Estradiol) CAS No. 350820-06-3 C24H32O8 M.W. 448.51 CAS No. 21881-45-8 C20H20D4O2 M.W. 300.43 CBNE-16533 C23H32O3 M.W. 356.51 CBNE-16534 CBNE-16536

Estradiol-d5 Estradiol Estradiol Enanthate C18H19O2D5 M.W. 277.42 CAS No. 50-28-2 CAS No. 4956-37-0 CBNE-16535 C18H24O2 M.W. 272.39 C25H36O3 M.W. 384.56 CBNE-16536 CBNE-16537

Estradiol-d4 (13S,14R,17R)- Ethynyl Estradiol CAS No. 66789-03-5 C20H20O2 M.W. 292.38 CAS No. 57-63-6 C18H20O2D4 M.W. 276.41 E-465 C20H24O2 M.W. 296.41 CBNE-16538 CBNE-16539

第 2 页 共 11 页 2-Hydroxy Ethynyl Estradiol 3-Cypionate Estradiol 6-alpha-Hydroxy Estradiol C20H24O3 M.W. 312.41 C26H36O3 M.W. 396.58 CAS No. 1229-24-9 CBNE-165310 CBNE-165311 C18H24O3 M.W. 288.39 CBNE-165312

Estradiol Valerate EP Impurity C Ethinyl Estradiol EP Impurity G 17-alpha-Ethynyl Estradiol-3-Sulfate CAS No. 95959-20-9 CAS No. 38002-18-5 CAS No. 24560-70-1 C23H30O3 M.W. 354.49 C20H22O3 M.W. 310.40 C20H24O5S M.W. 376.48 CBNE-165313 CBNE-165314 CBNE-165315

Ethynylestradiol EP Impurity E (6-alpha-Hydroxy Ethynylestradiol EP Impurity F Ethinylestradiol EP Impurity I (6,7-Didehydro Ethynylestradiol) (6-beta-Hydroxy Ethynylestradiol) Ethynyl Estradiol) CAS No. 27521-34-2 CAS No. 56324-28-8 CAS No. 67703-68-8 C20H24O3 M.W. 312.41 C20H24O3 M.W. 312.41 C20H22O2 M.W. 294.40 CBNE-165316 CBNE-165317 CBNE-165318

第 3 页 共 11 页 6- Valerate Estradiol Hemihydrate EP Impurity D Ethinylestradiol C24H34O3 M.W. 370.54 (delta-9(11)-Estradiol) CAS No. 57-63-6 CBNE-16530 CAS No. 791-69-5 C20H24O2 M.W. 296.41 C18H22O2 M.W. 270.37 E-461 CBNE-16531

Ethinylesteradiol EP Impurity H (16-Oxo- Ethinylesteradiol Impurity L 6-beta-Hydroxy Estradiol Ethinylesteradiol) C18H24O2 M.W. 272.39 CAS No. 3583-03-7 CAS No. 1350468-76-6 E-463 C18H24O3 M.W. 288.39 C20H22O3 M.W. 310.40 CBNE-16532 E-462

Estradiol Valerate EP Impurity E (3,17-Divalerate Estradiol Valerate rac-Ethinylestradiol EP Impurity H (Mixture Estradiol) CAS No. 979-32-8 of Diastereomers) CAS No. 63042-28-4 C23H32O3 M.W. 356.51 C20H22O3 M.W. 310.39 C28H40O4 M.W. 440.62 CBNE-16537 CBNE-16538 CBNE-16534

第 4 页 共 11 页 delta-9(11)-Estradiol 3-Enanthate delta-9(11)-Estradiol 17-Enanthate Ethinylestradiol EP Impurity A C25H34O3 M.W. 382.55 CAS No. 95960-05-7 (17-epi Ethylnyl Estradiol) CBNE-16539 C25H34O3 M.W. 382.54 CAS No. 4717-38-8 CBNE-165330 C20H24O2 M.W. 296.41 CBNE-165331

Ethinyl Estradiol EP Impurity B Ethinylestradiol Impurity M 17-epi Estradiol Valerate CAS No. 1231-96-5 CAS No. 1818-11-7 C23H32O3 M.W. 356.51 C20H22O2 M.W. 294.39 C21H24O2 M.W. 308.42 CBNE-165334 CBNE-165332 CBNE-165333

Ethynyl Estradiol EP Impurity L (17-epi-Estradiol) 17-Beta-Estradiol-3-O-Sulfate Estradiol EP Impurity B-d3 (Ethinyl Estradiol CAS No. 57-91-0 CAS No. 4999-79-5 EP Impurity L-d3) C18H24O2 M.W. 272.39 C18H23O5S Na M.W. 351.45 22.99 CAS No. 57-91-0 (non-labelled) CBNE-165335 CBNE-165336 C18H21D3O2 M.W. 275.41 CBNE-165338

第 5 页 共 11 页 Diethinylestradienol 6-Keto Estradiol Ethinylestradiol EP Impurity K CAS No. 79727-03-0 CAS No. 571-92-6 CAS No. 155683-61-7 C22H26O M.W. 306.45 C18H22O3 M.W. 286.37 C21H26O2 M.W. 310.44 CBNE-165339 CBNE-165341 CBNE-165342

Estradiol Hemihydrate EP Impurity C (4-Methyl Estradiol 3-Enanthate 4-Methyl Estradiol Enanthate Impurity Estradiol) CAS No. 55540-97-1 C26H38O3 M.W. 398.59 CAS No. 6171-48-8 C25H36O3 M.W. 384.56 CBNE-165345 C19H26O2 M.W. 286.42 CBNE-165340 CBNE-165344

Estradiol related compound B 4-Methyl Estradiol Valerate 4-Hydroxy estradiol 1-N7-guanine CAS No. 7291-41-0 CAS No. 1359847-37-2 CAS No. 178971-91-0 C18H22O2 M.W. 270.37 C24H34O3 M.W. 370.54 C23H27N5O4 M.W. 437.50 CBNE-165346 CBNE-165347 CBNE-165348

第 6 页 共 11 页 4-Hydroxy estradiol 1-N3-Adenine Impurity E (17-epi- Ethynyl Estradiol-3-Glucuronide CAS No. 428506-88-1 Estradiol Benzoate) CAS No. 60134-76-1 C23H27N5O3 M.W. 421.50 CAS No. 6045-53-0 C26H32O8 M.W. 472.53 CBNE-165349 C25H28O3 M.W. 376.50 E-464 CBNE-165350

(13S,14R,17S)-Ethinylestradiol (13S,14S,17R)-Ethinyl Estradiol (13S,14S,17S)-Ethinylestradiol C20H20O2 M.W. 292.38 CAS No. 1357266-17-1 CAS No. N/A E-466 C20H20O2 M.W. 292.38 C20H20O2 M.W. 292.38 E-467 E-468

delta-9(11)-Estradiol-d3 Estradiol 17-beta-Sulfate 17alpha;-Estradiol Sulfate Sodium CAS No. N/A C18H24O5S M.W. 352.45 CAS No. 56050-04-5 C18H19O2D3 M.W. 273.39 CBNE-165352 C18H23O5S . Na M.W. 351.45 22.99 CBNE-165351 CBNE-165353

第 7 页 共 11 页 Ethinyl Estradiol Impurity J (1-Methyl Ethinyl Ethinyl Estradiol EP Impurity M Ethinylestradiol-13C2 Estradiol) CAS No. 3240-39-9 CAS No. 57-63-6 (non-labelled) CAS No. 15071-66-6 C21H26O2 M.W. 310.44 C20H24O2 M.W. 298.39 C21H26O2 M.W. 310.44 CBNE-165354 E-4610 E-469

Estradiol Valerate EP Impurity H 2-Methoxy-Ethynyl Estradiol Ethynylestradiol Impurity 1 (2-Valeryl-17-beta-Estradiol-17-Valerate) CAS No. 22415-44-7 C22H26O4 M.W. 354.45 CAS No. 1421283-56-8 C21H26O3 M.W. 326.44 CBNE-165357 C28H40O4 M.W. 440.62 CBNE-165356 CBNE-165355

17-beta-Estradiol-13C2 17-alpha Estradiol Enanthate Estradiol Enanthate Acetate CAS No. 82938-05-4 CAS No. 10093-54-6 C27H38O4 M.W. 426.60 C18H24O2 M.W. 274.37 C25H36O3 M.W. 384.56 CBNE-165360 CBNE-165358 CBNE-165359

第 8 页 共 11 页 4-Methyl-17-alpha-Estradiol Delta-9-17-alpha-Estradiol Estradiol Valerate Impurity I C19H26O2 M.W. 286.42 C18H22O2 M.W. 270.37 C49H66O5 M.W. 735.07 CBNE-165361 CBNE-165362 CBNE-165363

Ethinylestradiol-d7 6-Oxo-Estradiol-17-Valerate Estradiol 3-Propyl Ether CAS No. 57-63-6 (non-d) CAS No. 1313382-51-2 CAS No. 22034-63-5 C20H17O2D7 M.W. 303.46 C23H30O4 M.W. 370.49 C21H30O2 M.W. 314.47 E-4611 CBNE-165364 CBNE-165365

beta-Estradiol 17-Acetate 16-Oxo Estradiol 6-Dehydro Estradiol 17-Valerate C20H26O3 M.W. 314.43 CAS No. 566-75-6 CAS No. 1313382-25-0 CBNE-165366 C18H22O3 M.W. 286.37 C23H30O M.W. 354.49 CBNE-165367 CBNE-165368

第 9 页 共 11 页 6-alpha-Hydroxy Estradiol 17-beta-Valerate Estradiol Valerate EP Impurity J Ethinylestradiol Dimer Impurity 1 CAS No. 1313382-26-1 C24H34O3 M.W. 370.53 CAS No. 303014-90-6 C23H32O4 M.W. 372.51 CBNE-165370 C40H46O4 M.W. 590.80 CBNE-165369 E-4612

Ethinylestradiol Dimer Impurity 2 2-Methyl Estradiol Estradiol 3-Methyl Ether CAS No. 303014-91-7 CAS No. 1818-12-8 CAS No. 1035-77-4 C40H46O4 M.W. 590.80 C19H26O2 M.W. 286.42 C19H26O2 M.W. 286.42 E-4613 CBNE-165371 CBNE-165372

Estradiol Impurity 1 CAS No. 57780-81-1 C18H24O4 M.W. 304.39 CBNE-165373

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