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ONE HUNDRED AND FIRST EDITION 2021 one hundred and first edition 2021 and first one hundred business magazine for international enterprises business trends 2 businessbusiness magazine for international trends 101 enterprises Dear readers, Business Trends is an international business magazine 2021 is a year of transition. Barring any unexpected catastrophes, Publisher: Business Trends individuals, businesses, and society can start to look forward to Kuipersdijk 20-73, 7512 CH Enschede shaping their futures rather than just grinding through the The Netherlands present. But the next normal is going to be different. It will not Tel: + 31 (0)53 574 55 47 mean going back to the conditions that prevailed in 2019. Just Fax: +31 (0)84 877 01 15 as the terms “pre-war” and “post-war” are commonly used to e-mail: [email protected] describe the 20th century, generations to come will likely internet: business-trends.nl discuss the pre-COVID-19 and post-COVID-19 eras. Editorial Staff: Patricia Allen, Laura van Beest, Bette Berlau, Anne Fransz, Mobility is emerging at an accelerated pace despite the Karin Gourley, Ellen Groen, industry’s overall global decline. This is in part because Donna Lee, Clare Martin, environmental, social and governance (ESG) trends are Monica Meijer, Christa Niemeijer, becoming non-negotiables for both consumers and leaders. Audrey Rhodes, Erna Welscher Meanwhile the instant access economy, created by the media Secretariat: Bette Berlau industry and streaming services, is beginning to have an Lay-out: Mooilucht, Hengelo, The Netherlands impact on all sectors of industry and business as consumers www.mooilucht.nl now also expect instant access for their physical deliveries. © Copyright 2021, all rights reserved. No part of this magazine may be reproduced In this issue of Business Trends, you will find several examples without the prior permission of the publisher. Photos accompanying the text are of how businesses are settling into the new normal. PostNord published with company approval unless stated otherwise. President and Group CEO Annemarie Gardshol talks about the big shift they’ve seen towards home deliveries and touchless deliveries. “Everybody had to step up and they all did. I can proudly see that there’s not been one single day of us letting the Nordics down.” On a broader organisational level, the pandemic has meant that PostNord had to accelerate investment and speed up plans for expansion. Meanwhile Kempower, positioned as a manufacturer and supplier of charging systems and solutions to customers ranging from charge point operators to public transport companies, is in the process of establishing subsidiaries in Norway, Germany and the Netherlands, the three front runners in European e-mobility. Tomi Ristimäki, CEO of Kempower Oy, says that the e-mobility market is growing faster than they even expected, particularly in densely populated Northern and Central Europe. “We can barely keep up. When I look at the big numbers and forecasts around e-mobility, I think they are still being conservative.” We hope you draw some inspiration from these stories and the other features in this issue as you prepare your business for a post-pandemic world. Ellen Groen Editor in Chief Growing in the Chinese one hundred and first edition 2021 and first one hundred edition 2021 and first one hundred business business magazine for magazine for international international enterprises enterprises business trends life sciences industry business trends 3 4 ABEC, a global provider of integrated solutions and services for biopharmaceutical bioprocessing equipment to China from manufacturing, recently announced it will design, manufacture, and install multiple its facility in Kells, Ireland. The Kells plant 4,000L fermenter trains for HEC Pharm’s manufacturing site in Guangzhou, China. The manufactures pressure vessels, skidded stainless-steel fermenter trains are custom designed to support HEC Pharm’s scale-up process equipment, and container initiative of their advanced insulin products. HEC Pharm is a significant contract win holders for ABEC’s Custom Single Run for them, according to Brady Cole, ABEC Vice President Equipment Solutions. “China is (CSR) single-use product line. a core market for us, and ABEC has been investing in and delivering solutions there for 750 Vw CSR®Dual over 12 years, supporting customers such as Qilu Pharmaceutical and WuXi Biologics. For ABEC, demand from China has been Purpose System ABEC’s office in Shanghai directly serves those customers.” on the up for a while now. In 2018, it (750L Fermenter / notably won a contract to equip contract 500L Bioreactor) ABEC has a long history in engineering side, we also help scale mammalian cell development and manufacturing systems for commercial scale culture and microbial fermentation organization (CDMO) WuXi Biologics’ customized, turn-key bioreactor and delivering complete stainless steel, the increased trailing by drug makers to manufacturing. Founded by Jack Wilson processes from the lab to production.” commercial manufacturing facility in fermentation solutions in both stainless single-use, or hybrid process solutions. use disposable systems commercially in 1974, their goal continues to be to Wuxi city, Jiangsu, with its 4,000 L CSR steel and single-use configurations. “We Finally, we are leveraging our long before the pandemic, demand for single- provide custom engineered solutions to Mr. Cole joined ABEC in 2002, and has disposable bioreactors. And in March are able to meet specific process, industry experience to provide use components has never been bigger, the Life Science Industry in support of held leadership positions in sales, 2021, it announced it will design, operational, and facility integration comprehensive value-added services, putting a strain on supply chains. As such, their efforts to provide the world with life applications, and product management. manufacture, and install multiple 4,000L needs for the full range of which is essential for our long-term ABEC is hearing from multiple customers changing therapies. In 2012 he established ABEC’s China fermenter trains for HEC Pharm’s biopharmaceutical products, including growth and success.” that there are significant delivery delays business unit, and he currently oversees manufacturing site in Guangzhou, China. monoclonal antibodies and other for single-use bags and tube sets. ABEC Mr. Cole explains that ABEC is focused on Product Management & Product The stainless-steel fermenter trains are recombinant proteins, vaccines, and gene Early in the COVID-19 pandemic, single- itself claims to have a lead time of around implementing clinical and commercial Development. custom designed to support HEC Pharm’s therapies.” use bioprocess systems and materials 16 weeks for its custom bioreactor bags, manufacturing processes. “We develop scale-up initiative of their advanced were highlighted as necessary tools in again building on what is the largest optimum process and equipment designs The bioreactor and bioproduction insulin products. ABEC was the first to market with large the development and commercial manufacturing capacity in this industry. for both the upstream and downstream equipment vendor ABEC has been scale single-use systems, and Mr. Cole manufacture of potential vaccines and The firm has seen significant increase for biopharm drug substance manufacturing. supplying the Chinese market for the HEC Pharm is a leader in producing expects that the industry’s adoption of therapies. The speed and flexibility its bioprocess systems over the past year, We are ensuring optimal equipment best part of a decade, after its Springfield, innovative medicines, generics, and this technology will continue to drive needed to make novel vaccines, including particularly its 4,000 L mammalian bags. sizing, automation, process flows, and Missouri facility obtained a China biologics. To ensure the highest growth for ABEC. “We also see growth mRNA, DNA, and viral vectors, meant cleaning/sterilization for maximum Manufacture License (CML) in 2010. In productivity and product quality, HEC from our ability to shorten our those platforms were largely built on productivity. Specific to the upstream 2018, it also received approval to supply Pharm selected ABEC for its long-term customers’ time to market by rapidly single-use technologies. Coupled with experience in fermenter design and scale up. ABEC’s 32,000m2 of manufacturing space, the largest global capacity in the industry, also ensures timely delivery to meet HEC Pharm’s rapid time to market needs. “Our facilities in the US and Ireland combined offer the largest ABEC biopharmaceutical manufacturing 3998 Schelden Circle capacity in the industry, including Bethlehem, PA 18017 two ISO-7 cleanrooms for Single- USA Use Disposable Container (DC) Website: www.abec.com manufacturing,” Mr. Cole points out. Email: [email protected] ABEC Field Service Where the company is also unique, in his Technicians view, is in their ability to provide ABEC Engineering & Project Management Personnel Tailor-made for optimal one hundred and first edition 2021 and first one hundred edition 2021 and first one hundred business business magazine for magazine for international international enterprises enterprises business trends therapy success business trends 5 6 In an unprecedented team effort, focused on overcoming oral pharmaceutical a very high expertise in micro-pellets design challenges presented by conventional manufacturing, Glatt Pharmaceutical and multiparticulate formulation,