The Paper War Over Smallpox Vaccination, 1721
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Program Evaluation Key Outcomes and Addressing Remaining
Vaccine 31S (2013) J73–J78 Contents lists available at ScienceDirect Vaccine jou rnal homepage: www.elsevier.com/locate/vaccine Key outcomes and addressing remaining challenges—Perspectives from a final ଝ evaluation of the China GAVI project a,1 a,1 a,1 a,1 b c Weizhong Yang , Xiaofeng Liang , Fuqiang Cui , Li Li , Stephen C. Hadler , Yvan J. Hutin , d a,∗ Mark Kane , Yu Wang a Chinese Center for Disease Control and Prevention, Beijing, China b Centers for Disease Control and Prevention, Atlanta, USA c Europe Center for Disease Control and Prevention, Stockholm, Sweden d Mercer Island, Washington, USA a r t a b i c s t l r e i n f o a c t Article history: During the China GAVI project, implemented between 2002 and 2010, more than 25 million children Received 6 June 2012 received hepatitis B vaccine with the support of project, and the vaccine proved to be safe and effective. Received in revised form 24 July 2012 With careful consideration for project savings, China and GAVI continually adjusted the budget, addi- Accepted 24 September 2012 tionally allowing the project to spend operational funds to support demonstration projects to improve timely birth dose (TBD), conduct training of EPI staff, and to monitor the project impact. Results from the final evaluation indicated the achievement of key outcomes. As a result of government co-investment, Keywords: human resources at county level engaged in hepatitis B vaccination increased from 29 per county on GAVI Project average in 2002 to 66 in 2009. All project counties funded by the GAVI project use auto-disable syringes Outcomes for hepatitis B vaccination and other vaccines. -
“Extracts from Some Rebel Papers”: Patriots, Loyalists, and the Perils of Wartime Printing
1 “Extracts from some Rebel Papers”: Patriots, Loyalists, and the Perils of Wartime Printing Joseph M. Adelman National Endowment for the Humanities Fellow American Antiquarian Society Presented to the Joint Seminar of the McNeil Center for Early American Studies And the Program in Early American Economy and Society, LCP Library Company of Philadelphia, 1314 Locust Street, Philadelphia 24 February 2012 3-5 p.m. *** DRAFT: Please do not cite, quote, or distribute without permission of the author. *** 2 The eight years of the Revolutionary War were difficult for the printing trade. After over a decade of growth and increasing entanglement among printers as their networks evolved from commercial lifelines to the pathways of political protest, the fissures of the war dispersed printers geographically and cut them off from their peers. Maintaining commercial success became increasingly complicated as demand for printed matter dropped, except for government printing, and supply shortages crippled communications networks and hampered printers’ ability to produce and distribute anything that came off their presses. Yet even in their diminished state, printers and their networks remained central not only to keeping open lines of communication among governments, armies, and civilians, but also in shaping public opinion about the central ideological issues of the war, the outcomes of battles, and the meaning of events affecting the war in North America and throughout the Atlantic world. What happened to printers and their networks is of vital importance for understanding the Revolution. The texts that historians rely on, from Common Sense and The Crisis to rural newspapers, almanacs, and even diaries and correspondence, were shaped by the commercial and political forces that printers navigated as they produced printed matter that defined the scope of debate and the nature of the discussion about the war. -
The Newspapers of the British Empire As a Matrix for The
Warner.communicating.liberty-1 Communicating Liberty: the Newspapers of the British Empire as a Matrix for the American Revolution William B. Warner “I beg your lordship’s permission to observe, and I do it with great concern, that this spirit of opposition to taxation and its consequences is so violent and so universal throughout America that I am apprehensive it will not be soon or easily appeased. The general voice speaks discontent… determined to stop all exports to and imports from Great Britain and even to silence the courts of law…foreseeing but regardless of the ruin that must attend themselves in that case, content to change a comfortable, for a parsimonious life,…” Lieutenant-Governor of South Carolina, Wm. Bull to Earl of Dartmouth, July 31, 1774. [Documents of the American Revolution, 1770-1783, Ed. K. G. Davies. (Dublin: Irish University Press, 1975) VIII: 1774, 154.] Momentous historical events often issue from a nexus of violence and communication. While American independence from Britain ultimately depended upon the spilling of blood on the battlefields of Bunker Hill, Saratoga and Yorktown, the successful challenge to the legitimacy of British rule in America was the culmination of an earlier communications war waged by American Whigs between the Stamp Act agitation of 1764-5 and the Coercive Acts of 1774. In response to the first of the Coercive acts--the Boston Port Bill--Boston Whigs secured a tidal wave of political and material support from throughout the colonies of British America. By the end of 1774, the American Secretary at Whitehall, Lord Dartmouth, was receiving reports from colonial Governors of North America, like the passage quoted above from the Lieutenant-Governor of South Caroline, William Bull. -
UNHCR COVID-19 Global Emergency Response
GLOBAL COVID-19 EMERGENCY RESPONSE 17 February 2021 UNHCR COVID-19 Preparedness and Response Highlights COVID-19 update ■ UNHCR and Gavi, the Vaccine Alliance, signed a Memorandum of Over 46,000 Understanding (MoU) on 03 February 2020, with the overall goal of ensuring reported cases refugees and other forcibly displaced can access vaccines on par with of COVID-19 nationals. The MoU also looks at expanding coverage and quality of among forcibly displaced people immunization services, promoting equity in access and uptake of vaccines, and strengthening health systems at community and primary care level. across 103 countries ■ Jordan has become one of the world’s first countries to start COVID-19 vaccinations for refugees, including vaccinations in Za’atari refugee camp on 15 February. UNHCR has been working with the Jordanian government to increase of vaccinate refugees and provide critical health, sanitation, hygiene and logistical some 7,500 cases compared support. UNHCR appeals to all countries to follow suit and include refugees in to the previous their national vaccination drives in line with COVAX allocation principles. reporting period ■ In 2020, 39.4 million persons of concern received COVID-19 assistance (numbers as of 08 February including access to protection services, shelter, health, and education. This 2021) includes over 8.5 million individuals who received cash assistance. ■ Despite an estimated 1.44 million refugees in urgent need of resettlement globally, less than 23,000 were resettled through UNHCR last year. These are the lowest refugee resettlement numbers UNHCR has witnessed in almost two decades. The drop stems from low quotas put forward by states, as well as the impact of COVID-19, which delayed departures and programmes. -
Vaccine Hesitancy
WHY CHILDREN WORKSHOP ON IMMUNIZATIONS ARE NOT VACCINATED? VACCINE HESITANCY José Esparza MD, PhD - Adjunct Professor, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA - Robert Koch Fellow, Robert Koch Institute, Berlin, Germany - Senior Advisor, Global Virus Network, Baltimore, MD, USA. Formerly: - Bill & Melinda Gates Foundation, Seattle, WA, USA - World Health Organization, Geneva, Switzerland The value of vaccination “The impact of vaccination on the health of the world’s people is hard to exaggerate. With the exception of safe water, no other modality has had such a major effect on mortality reduction and population growth” Stanley Plotkin (2013) VACCINES VAILABLE TO PROTECT AGAINST MORE DISEASES (US) BASIC VACCINES RECOMMENDED BY WHO For all: BCG, hepatitis B, polio, DTP, Hib, Pneumococcal (conjugated), rotavirus, measles, rubella, HPV. For certain regions: Japanese encephalitis, yellow fever, tick-borne encephalitis. For some high-risk populations: typhoid, cholera, meningococcal, hepatitis A, rabies. For certain immunization programs: mumps, influenza Vaccines save millions of lives annually, worldwide WHAT THE WORLD HAS ACHIEVED: 40 YEARS OF INCREASING REACH OF BASIC VACCINES “Bill Gates Chart” 17 M GAVI 5.6 M 4.2 M Today (ca 2015): <5% of children in GAVI countries fully immunised with the 11 WHO- recommended vaccines Seth Berkley (GAVI) The goal: 50% of children in GAVI countries fully immunised by 2020 Seth Berkley (GAVI) The current world immunization efforts are achieving: • Equity between high and low-income countries • Bringing the power of vaccines to even the world’s poorest countries • Reducing morbidity and mortality in developing countries • Eliminating and eradicating disease WHY CHILDREN ARE NOT VACCINATED? •Vaccines are not available •Deficient health care systems •Poverty •Vaccine hesitancy (reticencia a la vacunacion) VACCINE HESITANCE: WHO DEFINITION “Vaccine hesitancy refers to delay in acceptance or refusal of vaccines despite availability of vaccination services. -
Searchable PDF Document
This file may be searchable, depending on the operating system, browser and PDF viewer in use. Nov 1879 – Oct 1880 - Watertown Enterprise 11/12/1879 p.4 General Tom Thumb to entertain at Town Hall p.4 Story of new American Shade Company on Fayette St. 11/19/1879 p.3 Story on how Watertown is careless about its history 11/26/1879 p.3 Emery Mayo building new rental house on Walnut St. 12/03/1879 p.3 Two new streetlights on Arlington St. 12/10/1879 p.3 Town meeting on bringing in new water supply p.3 Alfred Hosmer purchases land and buildings on River St. for $1500 12/31/1879 p.3 George March presented with bronze statuary 1/28/1880 p.3 Annual report shows 86 deaths & 106 births 2/04/1880 p.2 Essays about Watertown history written by 13-year-old students p.4 Ad for a horse dentist 2/25/1880 Story about the advantages of being an “old maid” 3/31/1880 p.4 Part of Watertown annexed to Newton 4/14/1880 p.2 Railroad extended between Watertown & Newton p.3 Board of Health examines wells due to 3 children dying in one family of diphtheria 4/28/1880 p.3 Fire at Aetna Mills tenement building. First time fire alarm box was used 5/05/1880 p.2 P.T. Barnum circus ad p.4 Old fire horse “Jim” retires p.5 Mrs. Harrington attempts suicide for 3rd time 5/26/1880 Story on women gamblers 6/02/1880 p.3 Lighting of streets at night being copied by other towns 6/09/1880 p.2 Story on Walker & Pratt Company 6/16/1880 p.2 Story on Lewando’s French Dye House p.3 Strawberry Festival 7/14/1880 Aaron Burr love story p.3 Galen St. -
Will and Codicil I Benjamin Franklin of Philadelphia, Printer, Late Minister Plenipotentiary from the United States of America
Will and Codicil I Benjamin Franklin of Philadelphia, printer, late Minister Plenipotentiary from the United States of America to the Court of France, now President of the State of Pennsylvania, do make and declare my last will and testament as follows:— To my Son William Franklin late Governor of the Jerseys, I give and devise all the lands I hold or have a right to, in the province of Nova Scotia, to hold to him, his heirs, and assigns forever. I also give to him all my books and papers, which he has in his possession, and all debts standing against him on my account books, willing that no payment for, nor restitution of, the same be required of him, by my executors. The part he acted against me in the late war, which is of public notoriety, will account for my leaving him no more of an estate he endeavoured to deprive me of. Having since my return from France demolished the three houses in Market Street, between Third and Fourth Streets, fronting my dwelling-house, and erected two new and larger ones on the ground, and having also erected another house on the lot which formerly was the passage to my dwelling, and also a printing-office between my dwelling and the front houses; now I do give and devise my said dwelling-house, wherein I now live, my said three new houses, my printing-office and the lots of ground thereto belonging; also my small lot and house in Sixth Street, which I bought of the widow Henmarsh; also my pasture-ground which I have in Hickory Lane, with the buildings thereon; also my house and lot on the north side of -
Dr. Franklin, Citizen Scientist
DR. FRANKLIN, FRANKLIN, DR. CITIZEN SCIENTIST CITIZEN CITIZEN SCIENTIST CITIZEN SCIENTIST Janine Yorimoto Boldt With contributions by Emily A. Margolis and Introduction by Patrick Spero Edited by the Contents 5 INTRODUCTION Patrick Spero Published on the occasion of the exhibition 8 Dr. Franklin, Citizen Scientist April–December ACKNOWLEDGMENTS American Philosophical Society South Fifth Street 10 Philadelphia, PA ESSAY amphilsoc.org Dr. Franklin, Citizen Scientist is exhibition catalog was made possible by a grant from the Janine Yorimoto Boldt National Endowment for the Humanities. 41 A BENJAMIN FRANKLIN TIMELINE 42 ILLUSTRATED CHECKLIST Any views, ndings, conclusions, or recommendations expressed in this publication do not necessarily represent those of the Janine Yorimoto Boldt / Emily A. Margolis National Endowment for the Humanities. 106 EDITED BY the American Philosophical Society SELECTED BIBLIOGRAPHY PROJECT MANAGEMENT Mary Grace Wahl DESIGN barb barnett graphic design llc PRINTING Brilliant Graphics, Exton, PA Front cover: Charles Willson Peale, Portrait of Benjamin Franklin (detail), , APS. Inside front cover and last page: Adapted illustrations from Benjamin Franklin, Experiments and Observations on Electricity, rd ed. ( ), APS. Copyright © by the American Philosophical Society Library & Museum All rights reserved. Identiers: ISBN -- - - | LCCN Also available as a free downloadable PDF at: https://diglib.amphilsoc.org/franklinsenlightenment/ Introducti In , Benjamin Franklin and a group of other civically minded individuals got together to form something called the “American Philosophical Society.” Philosophy, at the time, had a much di¡erent meaning than it does today. To be a philosopher was to be one who systematically inquired into nature, often in ways that we would today consider science. e Society’s purpose was thus to “promote useful knowledge” by bringing the greatest thinkers in the British colonies together to share all that they knew and were learning. -
Predictors of Vaccine Hesitancy: Implications for COVID-19 Public Health Messaging
International Journal of Environmental Research and Public Health Review Predictors of Vaccine Hesitancy: Implications for COVID-19 Public Health Messaging Amanda Hudson 1,2,* and William J. Montelpare 3 1 Department of Mental Health and Addiction, Health PEI, Charlottetown, PE C1C 1M3, Canada 2 Department of Health Management, University of Prince Edward Island, Charlottetown, PE C1A 4P3, Canada 3 Department of Applied Human Sciences, University of Prince Edward Island, Charlottetown, PE C1A 4P3, Canada; [email protected] * Correspondence: [email protected] Abstract: Objectives: Successful immunization programs require strategic communication to increase confidence among individuals who are vaccine-hesitant. This paper reviews research on determinants of vaccine hesitancy with the objective of informing public health responses to COVID-19. Method: A literature review was conducted using a broad search strategy. Articles were included if they were published in English and relevant to the topic of demographic and individual factors associated with vaccine hesitancy. Results and Discussion: Demographic determinants of vaccine hesitancy that emerged in the literature review were age, income, educational attainment, health literacy, rurality, and parental status. Individual difference factors included mistrust in authority, disgust sensitivity, and risk aversion. Conclusion: Meeting target immunization rates will require robust public health campaigns that speak to individuals who are vaccine-hesitant in their attitudes and behaviours. Based on the assortment of demographic and individual difference factors that contribute Citation: Hudson, A.; Montelpare, to vaccine hesitancy, public health communications must pursue a range of strategies to increase W.J. Predictors of Vaccine Hesitancy: public confidence in available COVID-19 vaccines. Implications for COVID-19 Public Health Messaging. -
Franklin Handout
The Lives of Benjamin Franklin Smithsonian Associates Prof. Richard Bell, Department of History University of Maryland Richard-Bell.com [email protected] Try Your Hand at a Franklin Magic Square Complete this magic square using the numbers 1 to 16 (the magic number is 34 The Lives of Benjamin Franklin: A Selective Bibliography Bibliography prepared by Dr. Richard Bell. Introducing Benjamin Franklin - H.W. Brands, The First American: The Life and Times of Benjamin Franklin (2000) - Carl Van Doren, Benjamin Franklin (1938) - Walter Isaacson, Benjamin Franklin: An American Life (2003) - Leonard W Labaree,. et al., eds. The Papers of Benjamin Franklin (1959-) - J. A. Leo Lemay, The Life of Benjamin Franklin, vol. 1, Journalist, 1706–1730 (2005). - J. A. Leo Lemay, The Life of Benjamin Franklin, vol. 2, Printer and Publisher, 1730–1747 (2005) - J. A. Leo Lemay, The Life of Benjamin Franklin, vol. 3, Soldier, Scientist and Politician, 1748-1757 (2008) - Edmund S. Morgan, Benjamin Franklin (2002) - Carla Mulford, ed, Cambridge Companion to Benjamin Franklin (2008) - Page Talbott, ed., Benjamin Franklin: In Search of a Better World (2005) - David Waldstreicher, ed., A Companion to Benjamin Franklin (2011) - Esmond Wright, Franklin of Philadelphia (1986) Youth - Douglas Anderson, The Radical Enlightenments of Benjamin Franklin (1997) - Benjamin Franklin the Elder, Verses and Acrostic, The Papers of Benjamin Franklin Digital Edition http://franklinpapers.org/franklin/ (hereafter PBF), I:3-5 - BF (?) ‘The Lighthouse Tragedy’ and ‘The Taking of Teach the Pirate,’ PBF, I:6-7 - Silence Dogood, nos. 1, 4, PBF, I:8, I:14 - BF, A Dissertation on Liberty and Necessity (1725), PBF, I:57 - BF, ‘Article of Belief and Acts of Religion,’ PBF, I:101 - David D. -
From Apprentice to Journeyman to Partner: Benjamin Franklin's Workers and the Growth of the Early American Printing Trade
From Apprentice to Journeyman to Partner: Benjamin Franklin's Workers and the Growth of the Early American Printing Trade The lyf so short, the craft so long to lerne. —Geoffrey Chaucer, "The Parliament of Fowls" ANY APPRENTICES IN THE EARLY American printing trade must have felt as Chaucer's fabled craftsman did. Beginning M at a young age, they commonly spent up to seven years as contractually bound, unpaid laborers. They usually had to promise not to gamble, fornicate, frequent taverns, marry, and buy or sell or divulge secrets of the business. Apprentices worked long hours, often performed menial tasks, and were subjected to beatings—all without pay. Yet apprentices endured the arduous existence because it held for them the promise of eventual self-employment. Their goal was to learn a craft they could practice when their apprenticeship expired.1 The apprenticeship system was essential to the growth of the early American press. Apprenticeships to printers were a means of vocational education that replenished and augmented the craft's practitioners, thus insuring a sufficient supply of skilled labor through which the "art" (special skill) and the "mystery" (special knowledge) of printing 1 For an example of the apprentice's obligations, see Samuel Richardson, The Apprentice's Vade Mecum (1734j reprint ed., Los Angeles, 1975), 2-20. On the menial nature of some tasks, see O. Jocelyn Dunlop and Richard D. Denman, English Apprenticeship and Child Labour: A History (London, 1912), 19-20; Sharon V. Salinger, "To Serve Well and Faithfully": Labor and Indentured Servants in Pennsylvania, 1682-1800 (Cambridge, 1987), 7. -
Vaccine Adjuvants: from 1920 to 2015 and Beyond
Vaccines 2015, 3, 320-343; doi:10.3390/vaccines3020320 OPEN ACCESS vaccines ISSN 2076-393X www.mdpi.com/journal/vaccines Review Vaccine Adjuvants: from 1920 to 2015 and Beyond Alberta Di Pasquale 1,*, Scott Preiss 1, Fernanda Tavares Da Silva 1 and Nathalie Garçon 2 1 GSK Vaccines, Avenue Fleming, 1300 Wavre, Belgium; E-Mails: [email protected] (S.P.); [email protected] (F.T.D.S.) 2 Bioaster, 321 Avenue Jean Jaurès, 6700 Lyon, France; E-Mail: [email protected] * Author to whom correspondence should be addressed; E-Mail: [email protected]; Tel.: +32-10-85-3573. Academic Editor: Diane M. Harper Received: 23 February 2015 / Accepted: 9 April 2015 / Published: 16 April 2015 Abstract: The concept of stimulating the body’s immune response is the basis underlying vaccination. Vaccines act by initiating the innate immune response and activating antigen presenting cells (APCs), thereby inducing a protective adaptive immune response to a pathogen antigen. Adjuvants are substances added to vaccines to enhance the immunogenicity of highly purified antigens that have insufficient immunostimulatory capabilities, and have been used in human vaccines for more than 90 years. While early adjuvants (aluminum, oil-in-water emulsions) were used empirically, rapidly increasing knowledge on how the immune system interacts with pathogens means that there is increased understanding of the role of adjuvants and how the formulation of modern vaccines can be better tailored towards the desired clinical benefit. Continuing safety evaluation of licensed vaccines containing adjuvants/adjuvant systems suggests that their individual benefit-risk profile remains favorable.