(Non)Parallel Evolution 3 4 Daniel I. Bolnick1,2*, Rowan Barrett3, Krista

Total Page:16

File Type:pdf, Size:1020Kb

(Non)Parallel Evolution 3 4 Daniel I. Bolnick1,2*, Rowan Barrett3, Krista 1 2 3 (Non)Parallel Evolution 4 5 Daniel I. Bolnick1,2*, Rowan Barrett3, Krista Oke3,4 , Diana J. Rennison5 , Yoel E. Stuart1 6 7 1 Department of Integrative Biology, University of Texas at Austin, Austin TX 78712, USA; 8 [email protected]; [email protected] 9 2 Department of Ecology and Evolution, University of Connecticut, Storrs CT 06268, USA (as of 10 07/2018) 11 3 Redpath Museum, McGill University, Montreal, Quebec, Canada; [email protected] 12 4 Department of Ecology and Evolutionary Biology, University of California Santa Cruz, Santa 13 Cruz, CA, 95060, USA; [email protected] 14 5 Institute of Ecology and Evolution, University of Bern, 3012 Bern, Switzerland; 15 [email protected] 16 17 * Corresponding author: Email: [email protected] Telephone: +011 (512) 471-2824 18 19 20 Running title: “(Non)Parallel Evolution” 21 22 1 23 Abstract 24 Parallel evolution across replicate populations has provided evolutionary biologists with iconic 25 examples of adaptation. When multiple populations colonize seemingly similar habitats, they 26 may evolve similar genes, traits, or functions. Yet, replicated evolution in nature or in the lab 27 often yields inconsistent outcomes: some replicate populations evolve along highly similar 28 trajectories, whereas other replicate populations evolve to different extents or in atypical 29 directions. To understand these heterogeneous outcomes, biologists are increasingly treating 30 parallel evolution not as a binary phenomenon but rather as a quantitative continuum ranging 31 from nonparallel to parallel. By measuring replicate populations’ positions along this 32 “(non)parallel” continuum, we can test hypotheses about evolutionary and ecological factors that 33 influence the likelihood of repeatable evolution. We review evidence regarding the distribution of 34 (non)parallel evolution in the laboratory and in nature and enumerate the many genetic and 35 evolutionary processes that contribute to variation in the extent of parallel evolution. 36 37 Key Words: Adaptation, Convergence, Divergence, Many-to-One Mapping, Nonparallel, 38 Parallel Evolution 2 39 I. INTRODUCTION 40 41 Parallel evolution holds a special place in the annals of evolutionary biology because it provides 42 strong evidence for adaptation. The replicated independent evolution of similar traits leads us to 43 infer that evolution was driven by a deterministic process, most likely natural selection (Harvey 44 & Pagel 1991). Biologists therefore use the repeated, parallel evolution of genes, phenotypes, 45 or ecotypes to infer that (i) similar environments impose similar natural selection, (ii) there exist 46 few solutions to this selection, and (iii) the traits or genes that evolve in parallel are adaptations. 47 These inferences offer the hope that, in some situations, evolution may even be predictable 48 enough that we can anticipate evolution of pests or disease-causing agents, or evolutionary 49 responses to anthropogenic environmental change (Agrawal 2017, Day 2012, de Visser & Krug 50 2014, Langerhans 2017). However, this optimistic goal of predicting future evolution is only 51 plausible if parallel evolution is common and strong. 52 There are many textbook cases of parallel evolution that have rightfully received a lot of 53 attention (e.g., Colosimo et al 2005, Elmer et al 2014, Khaitovich et al 2005, Thompson et al 54 1997). But, are these representative of replicated evolution more generally, or have we given 55 undue attention to a few exceptionally parallel genes, traits, or species? If we objectively 56 surveyed replicate populations in similar habitats, how common and how extensive would 57 parallel evolution be? What fraction of replicate populations would evolve in parallel, for what 58 number of traits? Conversely, how often would replicate populations diverge genetically or 59 phenotypically despite experiencing similar environments? 60 As we describe in this review, there is widespread evidence that replicate populations in 61 similar environments sometimes evolve similar traits (or genes) and sometimes evolve 62 dissimilar traits (or genes). Thus, we argue here that parallel evolution is best viewed as an 63 extreme end of a quantitative continuum of ‘(non)parallel evolution’ (see Fig. 1 for a visual 64 glossary). Section II provides examples of this continuum of (non)parallel evolution, drawn from 65 settings of practical interest (e.g., disease, agriculture) to motivate study of (non)parallelism. 66 After addressing some semantics (Section III), we then describe approaches to quantify 67 (non)parallel evolution (Section IV), what those measures have revealed (Section V), and what 68 we learn about evolutionary biology more generally as a result (Section VI). Throughout this 69 essay, we seek answers to questions such as: What evolutionary forces generate variation in 70 (non)parallelism among replicate populations? What kinds of traits are more or less parallel? 71 Perhaps most fundamentally: when we see deviations from parallel evolution, what are we to 72 conclude about adaptation? Biologists use parallel evolution as evidence of adaptation, but 3 73 when evolution in similar environments falls toward the nonparallel end of the continuum, should 74 we infer there is maladaptation, neutral evolution, or adaptation? 75 76 77 II. INCOMPLETELY PARALLEL EVOLUTION 78 Our first goal for this review is to motivate it. That is, we must establish that evolution is often 79 less parallel than we might have reasonably expected. Intuitively, we expect that initially similar 80 populations that are exposed to similar selection pressures will evolve similar phenotypic 81 adaptations. As we show in this section, however, in many contexts this expectation is only 82 partly true, and the examples of nonparallel evolution described here illustrate the need for 83 quantitative rather than binary approaches to studying parallel evolution. In presenting these 84 cases of (non)parallel evolution, we focus on evolution in highly applied contexts to convey the 85 point that this evolutionary continuum has very practical consequences and should be 86 considered in an interdisciplinary way. 87 88 II.1 (Non)parallelism in cancer 89 Cancer tumors are evolving populations of cells (Burrell et al 2013, Nowell 1976, Shpak & Lu 90 2016, Swanton 2014). Tumors originate when somatic mutations confer an ‘escape’ from 91 normal cell cycle regulation. Growing tumors contain multiple genetically divergent cell lines that 92 differ in their ability to proliferate, evade the immune system, resist chemotherapy, and 93 metastasize. This genetic variation can therefore be subject to strong selection within a tumor. 94 Typically, each cancer patient is an independent, replicated case of one or more oncogenic 95 mutations that initiate a tumor and the subsequent clonal selection on additional mutations. If 96 tumor evolution is highly parallel, then the same mutations in the same genes should evolve 97 repeatedly in most or all patients. It is increasingly clear, however, that ostensibly similar tumors 98 (i.e., same tissue and histology) often comprise fundamentally different mutations across 99 patients. 100 In an experimental evolution study, Tegze et al. (2012) applied identical selection (18 101 months of chemotherapy) to 29 identical artificial tumors that were all derived from one breast 102 cancer cell line. Only 18 of the 29 replicates evolved resistance, and within those resistant 103 replicates, the underlying genetic changes were nonparallel, affecting different cell functions 104 (Tegze et al 2012). This result highlights some key themes: first, even identical starting 105 populations subjected to identical selection can exhibit nonparallel evolutionary responses. 4 106 Second, parallel evolution of resistance (an emergent function) occurred without parallel 107 evolution of the underlying genes. 108 Such evolutionary inconsistency also occurs in real cancer patients. Takahashi et al 109 (2007) compared allele frequency differences between primary versus metastatic lung tumor 110 genomes to find targets of selection during metastasis. Most of these rapidly evolving genes 111 experienced selection in only one or a few patients, and the rest were never shared by more 112 than half the patients (Takahashi et al 2007 ). This (non)parallel evolution is why cancer 113 treatment is increasingly reliant not on tissue type or histological traits but rather on 114 personalized genomics to tailor therapies to the particular causal gene(s) in an individual 115 (Abbosh et al 2017). 116 117 II.2 (Non)parallel evolution in pathogens 118 Like cancer, human pathogens show (non)parallel evolution in response to therapies and host 119 immunity. In HIV patients with low viral load during drug therapy, an interruption to therapy often 120 results in a rapid rebound of viral load. One study of 12 chronic HIV patients revealed that the 121 HIV-1 gp120 gene evolved rapidly in each patient when they experienced this viral rebound 122 (Martinez-Picado et al 2002). If gp120 evolved in parallel following therapy-interruption, we 123 could potentially develop drugs targeting the gp120 variants that facilitate rapid viral rebound. 124 However, for unknown reasons, different mutations contributed to this rebound in each patient, 125 so we cannot develop therapies that anticipate gp120 evolution following treatment interruption. 126 Human macrophages protect against pathogenic strains of Escherichia coli, but this 127 bacterium sometimes
Recommended publications
  • (Pentatomidae) DISSERTATION Presented
    Genome Evolution During Development of Symbiosis in Extracellular Mutualists of Stink Bugs (Pentatomidae) DISSERTATION Presented in Partial Fulfillment of the Requirements for the Degree Doctor of Philosophy in the Graduate School of The Ohio State University By Alejandro Otero-Bravo Graduate Program in Evolution, Ecology and Organismal Biology The Ohio State University 2020 Dissertation Committee: Zakee L. Sabree, Advisor Rachelle Adams Norman Johnson Laura Kubatko Copyrighted by Alejandro Otero-Bravo 2020 Abstract Nutritional symbioses between bacteria and insects are prevalent, diverse, and have allowed insects to expand their feeding strategies and niches. It has been well characterized that long-term insect-bacterial mutualisms cause genome reduction resulting in extremely small genomes, some even approaching sizes more similar to organelles than bacteria. While several symbioses have been described, each provides a limited view of a single or few stages of the process of reduction and the minority of these are of extracellular symbionts. This dissertation aims to address the knowledge gap in the genome evolution of extracellular insect symbionts using the stink bug – Pantoea system. Specifically, how do these symbionts genomes evolve and differ from their free- living or intracellular counterparts? In the introduction, we review the literature on extracellular symbionts of stink bugs and explore the characteristics of this system that make it valuable for the study of symbiosis. We find that stink bug symbiont genomes are very valuable for the study of genome evolution due not only to their biphasic lifestyle, but also to the degree of coevolution with their hosts. i In Chapter 1 we investigate one of the traits associated with genome reduction, high mutation rates, for Candidatus ‘Pantoea carbekii’ the symbiont of the economically important pest insect Halyomorpha halys, the brown marmorated stink bug, and evaluate its potential for elucidating host distribution, an analysis which has been successfully used with other intracellular symbionts.
    [Show full text]
  • Alfred Russel Wallace and the Darwinian Species Concept
    Gayana 73(2): Suplemento, 2009 ISSN 0717-652X ALFRED RUSSEL WALLACE AND THE Darwinian SPECIES CONCEPT: HIS paper ON THE swallowtail BUTTERFLIES (PAPILIONIDAE) OF 1865 ALFRED RUSSEL WALLACE Y EL concepto darwiniano DE ESPECIE: SU TRABAJO DE 1865 SOBRE MARIPOSAS papilio (PAPILIONIDAE) Jam ES MA LLET 1 Galton Laboratory, Department of Biology, University College London, 4 Stephenson Way, London UK, NW1 2HE E-mail: [email protected] Abstract Soon after his return from the Malay Archipelago, Alfred Russel Wallace published one of his most significant papers. The paper used butterflies of the family Papilionidae as a model system for testing evolutionary hypotheses, and included a revision of the Papilionidae of the region, as well as the description of some 20 new species. Wallace argued that the Papilionidae were the most advanced butterflies, against some of his colleagues such as Bates and Trimen who had claimed that the Nymphalidae were more advanced because of their possession of vestigial forelegs. In a very important section, Wallace laid out what is perhaps the clearest Darwinist definition of the differences between species, geographic subspecies, and local ‘varieties.’ He also discussed the relationship of these taxonomic categories to what is now termed ‘reproductive isolation.’ While accepting reproductive isolation as a cause of species, he rejected it as a definition. Instead, species were recognized as forms that overlap spatially and lack intermediates. However, this morphological distinctness argument breaks down for discrete polymorphisms, and Wallace clearly emphasised the conspecificity of non-mimetic males and female Batesian mimetic morphs in Papilio polytes, and also in P.
    [Show full text]
  • Evolution Activity, Grade 11
    Evolution Activity, Grade 11 Evolution Activities for Grade 11 Students at the Toronto Zoo 1 Evolution Activity, Grade 11 Table of Contents Pre-Zoo Activity 3-8 • Think, Pair, Share – Animals in Society and Role of Zoos 3-5 o Description 3 o Materials 3 o Four Corners Activity 6 o Background Information 7-8 Zoo Activity 9-19 • Teacher’s Notes 9-13 o General Information, Curriculum expectations, 9-10 materials, procedure o Evaluation Rubrics 11-12 o Glossary 13 • Student Assignment 14-19 o Part 1 – Mission Preparation at the Zoo 15-16 (Observation Sheets) o Part 2 – Scientific Notes 17 o Part 3 – Documentation: The Story 18 o Appendix – Animal signs 19 Evaluation 20 2 Evolution Activity, Grade 11 Suggested Pre-zoo activity Time needed : 35 minutes (or more) Type of activity : pair-share, small-group (approximately 2-3 students) Objective : encourage students to think about and evaluate the roles of animals in our society and the purposes of zoos along with their own attitudes or stands toward zoos Materials needed : a set of 8-16 statements and a mode of ranking (either above the line-below the line or diamond style ranking system) Special note : In order to manage time, teacher can chose to use any number of the statements as long as the 4 core statements listed bellow are included. Task : students work together to rank the statements about the treatment of animals. They should work together and try to negotiate a consensus, but if this is impossible they can either leave out the particular statement or write down a few lines in their notes as to why they would place them in a different category.
    [Show full text]
  • Countershading in Zebrafish Results from an Asip1 Controlled
    www.nature.com/scientificreports OPEN Countershading in zebrafsh results from an Asip1 controlled dorsoventral gradient of pigment Received: 1 October 2018 Accepted: 12 February 2019 cell diferentiation Published: xx xx xxxx Laura Cal1, Paula Suarez-Bregua1, Pilar Comesaña1, Jennifer Owen2, Ingo Braasch3, Robert Kelsh 2, José Miguel Cerdá-Reverter4 & Josep Rotllant1 Dorso-ventral (DV) countershading is a highly-conserved pigmentary adaptation in vertebrates. In mammals, spatially regulated expression of agouti-signaling protein (ASIP) generates the diference in shading by driving a switch between the production of chemically-distinct melanins in melanocytes in dorsal and ventral regions. In contrast, fsh countershading seemed to result from a patterned DV distribution of diferently-coloured cell-types (chromatophores). Despite the cellular diferences in the basis for counter-shading, previous observations suggested that Agouti signaling likely played a role in this patterning process in fsh. To test the hypotheses that Agouti regulated counter-shading in fsh, and that this depended upon spatial regulation of the numbers of each chromatophore type, we engineered asip1 homozygous knockout mutant zebrafsh. We show that loss-of-function asip1 mutants lose DV countershading, and that this results from changed numbers of multiple pigment cell-types in the skin and on scales. Our fndings identify asip1 as key in the establishment of DV countershading in fsh, but show that the cellular mechanism for translating a conserved signaling gradient into a conserved pigmentary phenotype has been radically altered in the course of evolution. Most vertebrates exhibit a dorso-ventral pigment pattern characterized by a light ventrum and darkly colored dorsal regions. Tis countershading confers UV protection against solar radiation, but also is proposed to pro- vide anti-predator cryptic pigmentation.
    [Show full text]
  • Convergent Evolution of Seasonal Camouflage in Response to Reduced Snow Cover Across the Snowshoe Hare Range
    ORIGINAL ARTICLE doi:10.1111/evo.13976 Convergent evolution of seasonal camouflage in response to reduced snow cover across the snowshoe hare range Matthew R. Jones,1,2 L. Scott Mills,3,4 Jeffrey D. Jensen,5 and Jeffrey M. Good1,3,6 1Division of Biological Sciences, University of Montana, Missoula, Montana 59812 2E-mail: [email protected] 3Wildlife Biology Program, University of Montana, Missoula, Montana 59812 4Office of Research and Creative Scholarship, University of Montana, Missoula, Montana 59812 5School of Life Sciences, Arizona State University, Tempe, Arizona 85281 6E-mail: [email protected] Received January 22, 2020 Accepted April 2, 2020 Determining how different populations adapt to similar environments is fundamental to understanding the limits of adaptation under changing environments. Snowshoe hares (Lepus americanus) typically molt into white winter coats to remain camouflaged against snow. In some warmer climates, hares have evolved brown winter camouflage—an adaptation that may spread in re- sponse to climate change. We used extensive range-wide genomic data to (1) resolve broad patterns of population structure and gene flow and (2) investigate the factors shaping the origins and distribution of winter-brown camouflage variation. Incoastal Pacific Northwest (PNW) populations, winter-brown camouflage is known to be determined by a recessive haplotype atthe Agouti pigmentation gene. Our phylogeographic analyses revealed deep structure and limited gene flow between PNW and more north- ern Boreal populations, where winter-brown camouflage is rare along the range edge. Genome sequencing of a winter-brown snowshoe hare from Alaska shows that it lacks the winter-brown PNW haplotype, reflecting a history of convergent phenotypic evolution.
    [Show full text]
  • The Molecular Basis of Phenotypic Convergence
    ES45CH10-Rosenblum ARI 15 October 2014 11:31 The Molecular Basis of Phenotypic Convergence Erica Bree Rosenblum,1 Christine E. Parent,1,2 and Erin E. Brandt1 1Department of Environmental Science, Policy, and Management, University of California, Berkeley, California 94720; email: [email protected], [email protected] 2Department of Biological Sciences, University of Idaho, Moscow, Idaho 83844; email: [email protected] Annu. Rev. Ecol. Evol. Syst. 2014. 45:203–26 Keywords First published online as a Review in Advance on convergent evolution, parallelism, genetics, nonmodel species September 29, 2014 The Annual Review of Ecology, Evolution, and Abstract Systematics is online at ecolsys.annualreviews.org Understanding what aspects of evolution are predictable, and repeatable, is a This article’s doi: central goal of biology. Studying phenotypic convergence (the independent 10.1146/annurev-ecolsys-120213-091851 evolution of similar traits in different organisms) provides an opportunity to Copyright c 2014 by Annual Reviews. address evolutionary predictability at different hierarchical levels. Here we All rights reserved focus on recent advances in understanding the molecular basis of conver- Annu. Rev. Ecol. Evol. Syst. 2014.45:203-226. Downloaded from www.annualreviews.org Access provided by University of California - Berkeley on 01/30/15. For personal use only. gence. Understanding when, and why, similar molecular solutions are used repeatedly provides insight into the constraints that shape biological diver- sity. We first distinguish between convergence as a phenotypic pattern and parallelism as a shared molecular basis for convergence. We then address the overarching question: What factors influence when parallel molecular mechanisms will underlie phenotypic convergence? We present four core determinants of convergence (natural selection, phylogenetic history, pop- ulation demography, and genetic constraints) and explore specific factors that influence the probability of molecular parallelism.
    [Show full text]
  • Differential Evolvability Along Lines of Least Resistance of Upper and Lower Molars in Island House Mice
    Differential Evolvability Along Lines of Least Resistance of Upper and Lower Molars in Island House Mice Sabrina Renaud1*, Sophie Pantalacci2, Jean-Christophe Auffray3 1 Laboratoire de Biome´trie et Biologie Evolutive, Universite´ Lyon 1, CNRS, Villeurbanne, France, 2 Molecular Zoology Team, Institut de Ge´nomique Fonctionnelle de Lyon, Universite´ de Lyon, CNRS, Ecole Normale Supe´rieure de Lyon, Lyon, France, 3 Institut des Sciences de l’Evolution, Universite´ Montpellier 2, CNRS, Montpellier, France Abstract Variation within a population is a key feature in evolution, because it can increase or impede response to selection, depending on whether or not the intrapopulational variance is correlated to the change under selection. Hence, main directions of genetic variance have been proposed to constitute ‘‘lines of least resistance to evolution’’ along which evolution would be facilitated. Yet, the screening of selection occurs at the phenotypic level, and the phenotypic variance is not only the product of the underlying genetic variance, but also of developmental processes. It is thus a key issue for interpreting short and long term evolutionary patterns to identify whether main directions of phenotypic variance indeed constitute direction of facilitated evolution, and whether this is favored by developmental processes preferably generating certain phenotypes. We tackled these questions by a morphometric quantification of the directions of variance, compared to the direction of evolution of the first upper and lower molars of wild continental and insular house mice. The main phenotypic variance indeed appeared as channeling evolution between populations. The upper molar emerged as highly evolvable, because a strong allometric component contributed to its variance.
    [Show full text]
  • Convergent Evolution
    Exploring the KU Natural History Museum Convergent Evolution Target Audience: Middle school and above Differentiated Instruction Summary Strategy Levels Content/Process/Product Grouping(s) Learning modalities Whole group • Level 1 – Visual (spatial) Small groups Process Cubing Level 2 – Kinesthetic (physical) Peer partners • Product • Level 3 – Verbal (linguistic) Homogeneous Heterogeneous * Varied grouping options can be used for this activity, depending on student needs and chaperone ability. Objectives: Explore examples of convergent evolution in vertebrates. Pre-assessment/Prior Knowledge: Prior to their visit, students should be familiar with the idea of convergent evolution, overall evolutionary relationships/classification of vertebrate groups and basic anatomy of those groups. Activity Description: Students explore the idea of convergent evolution through museum exhibits through different learning modalities. Materials Needed: • Student o Cubes (three levels, see attached) o Paper and pencils (alternatively you could use flipchart paper and markers, whiteboards and dry erase markers) o Optional (cell phones or other recording device for visual or kinesthetic levels) Note: Format to record/present findings determined by individual teacher. Provide clear instructions about expectations for documenting participation, particularly for verbal/spatial and body/kinesthetic levels (e.g. stage direction, audio/video recording). • Teacher o Content Outline o Cube labels o Cube template Content: Convergence Overview Convergent evolution refers to the similarities in biological traits that arise independently in organisms that are not closely related, e.g. wings in birds, bats and insects. Similarity among organisms and their structures that was not inherited from a common ancestor is considered to be homoplasy. This can be contrasted with homology, which refers to similarity of traits due to common ancestry.
    [Show full text]
  • The Genetic Causes of Convergent Evolution
    Nature Reviews Genetics | AOP, published online 9 October 2013; doi:10.1038/nrg3483 REVIEWS The genetic causes of convergent evolution David L. Stern Abstract | The evolution of phenotypic similarities between species, known as convergence, illustrates that populations can respond predictably to ecological challenges. Convergence often results from similar genetic changes, which can emerge in two ways: the evolution of similar or identical mutations in independent lineages, which is termed parallel evolution; and the evolution in independent lineages of alleles that are shared among populations, which I call collateral genetic evolution. Evidence for parallel and collateral evolution has been found in many taxa, and an emerging hypothesis is that they result from the fact that mutations in some genetic targets minimize pleiotropic effects while simultaneously maximizing adaptation. If this proves correct, then the molecular changes underlying adaptation might be more predictable than has been appreciated previously. (FIG. 1) Fitness Different species often evolve similar solutions to envi­ introgression . It is worth distinguishing between The potential evolutionary ronmental challenges. Insects, birds and bats evo­ these scenarios because each provides evidence for a dif­ success of a genotype, defined lved wings, and octopi, vertebrates and spiders ferent evolutionary path3. The first case, the independent as the reproductive success or evolved focusing eyes. Phenotypic convergence provides origin and spread of mutations, has been called parallel the proportion of genes that an individual leaves in the gene compelling evidence that ecological circumstances can genetic evolution. I suggest that the evolution of alleles 1,2 pool of the next generation in a select for similar evolutionary solutions .
    [Show full text]
  • Johnson Stander 2020
    Gene Regulatory Network Homoplasy Underlies Recurrent Sexually Dimorphic Fruit Fly Pigmentation Jesse Hughes, Rachel Johnson, and Thomas M. Williams The Department of Biology at the University of Dayton; 300 College Park, Dayton, OH 45469 ABSTRACT Widespread Dimorphism in Sophophora and Beyond Pigment Metabolic Pathway Utilization in H. duncani Species with dimorphic tergite pigmentation are Traits that appear discontinuously along phylogenies may be explained by independent ori- widespread throughout the Drosophila genus. (A-E) Female and (A’-E’) male expressions of H. duncani gins (homoplasy) or repeated loss (homology). While discriminating between these models Sophophora subgenus species groups and species pigment metabolic pathway genes, and (F and F’) cartoon is difficult, the dissection of gene regulatory networks (GRNs) which drive the development are indicated by the gray background. D. busckii and representation of the pigmentation phenotype. (G) of such repeatedly occurring traits can offer a mechanistic window on this fundamental Summary of the H. duncani pathway use includes robust D. funebris are included as non-Sophophora species problem. The GRN responsible for the male-specific pattern of Drosophila (D.) melano- expression of all genes, with dimorphic expressions of Ddc, from the Drosophila genus that respectively exhibit gaster melanic tergite pigmentation has received considerable attention. In this system, a ebony, tan, and yellow. (A, A’) pale, (B, B’) Ddc, (C, C’) monomorphic and dimorphic patterns of tergite metabolic pathway of pigmentation enzyme genes is expressed in spatial and sex-specific ebony, (D, D’) tan, and (E, E’) yellow. Red arrowheads pigmentation. The homologous A5 and A6 segment (i.e., dimorphic) patterns. The dimorphic expression of several genes is regulated by the indicate robust patterns of dimorphic expression in the tergites are indicated for each species, the segments Bab transcription factors, which suppress pigmentation enzyme expression in females, by dorsal abdominal epidermis.
    [Show full text]
  • Progress and Competition in Macroevolution
    Biol . Rev . (1987). 62. pp. 305-338 Printed in Great Britain PROGRESS AND COMPETITION IN MACROEVOLUTION BY MICHAEL J . BENTON Department of Geology. The Queen’s University of Belfast. Belfast. BT7 INN. Northern Ireland (Received I 3 August 1985. accepted 23 February 1987) CONTENTS I . Introduction ........ I1. Improvements in competitive ability through time ........ (I) Evolutionary progress ............ (2) Increase in morphological complexity ......... (3) The expansion of life ............. (4) Evolutionary trends ............. (5) Increased effectiveness of adaptation .......... I11 . Competition in microevolution ........... (I) Competition and natural selection .......... (2) The evolutionary effects of interspecific competition ....... (3) The effects of interspecific competition on community structure .... IV . Competition in macroevolution ........... (I) Extinction and competition ........... (2) The Red Queen .............. (3) The community paradigm ............ (4) Evolutionary rates and competitive ability ......... V . Competition and major ecological replacements ........ (I) Key adaptations and replacements ........... (2) Patterns of ecological replacement ........... (3) The evidence for double-wedge patterns (differential survival) in the fossil record . (4) The evidence that differential survival was caused by competition .... (5) Alternatives to competition ........... VI . The problems of invoking large-scale competition ........ VII . Summary ................ VIII . Acknowledgements .............. IX. References
    [Show full text]
  • Phylogeny of the Procyonidae (Mammalia: Carnivora): Molecules, Morphology and the Great American Interchange
    Molecular Phylogenetics and Evolution 43 (2007) 1076–1095 www.elsevier.com/locate/ympev Phylogeny of the Procyonidae (Mammalia: Carnivora): Molecules, morphology and the Great American Interchange a, b c a Klaus-Peter KoepXi ¤, Matthew E. Gompper , Eduardo Eizirik , Cheuk-Chung Ho , Leif Linden a, Jesus E. Maldonado d, Robert K. Wayne a a Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095-1606, USA b Department of Fisheries and Wildlife Sciences, University of Missouri, Colombia, MO 65211, USA c Faculdade de Biociencias, PUCRS, Av. Ipiranga, 6681, Predio 12, Porto Alegre, RS 90619-900, Brazil d Smithsonian Institution, NMNH/NZP—Genetic Program, 3001 Connecticut Avenue NW, Washington, DC 20008, USA Received 10 June 2006; revised 22 September 2006; accepted 2 October 2006 Available online 11 October 2006 Abstract The Procyonidae (Mammalia: Carnivora) have played a central role in resolving the controversial systematics of the giant and red pandas, but phylogenetic relationships of species within the family itself have received much less attention. Cladistic analyses of morpho- logical characters conducted during the last two decades have resulted in topologies that group ecologically and morphologically similar taxa together. SpeciWcally, the highly arboreal and frugivorous kinkajou (Potos Xavus) and olingos (Bassaricyon) deWne one clade, whereas the more terrestrial and omnivorous coatis (Nasua), raccoons (Procyon), and ringtails (Bassariscus) deWne another clade, with the similar-sized Nasua and Procyon joined as sister taxa in this latter group. These relationships, however, have not been tested with molecu- lar sequence data. We examined procyonid phylogenetics based on combined data from nine nuclear and two mitochondrial gene seg- ments totaling 6534 bp.
    [Show full text]