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Effect of Chronic and Intermittent Calorie Restriction on Serum Adiponectin and Leptin and Mammary Tumorigenesis
Published OnlineFirst January 21, 2011; DOI: 10.1158/1940-6207.CAPR-10-0140 Cancer Prevention Research Article Research Effect of Chronic and Intermittent Calorie Restriction on Serum Adiponectin and Leptin and Mammary Tumorigenesis Olga P. Rogozina1, Melissa J.L. Bonorden1, Christine N. Seppanen1, Joseph P. Grande2, and Margot P. Cleary1 Abstract The effect of chronic (CCR) and intermittent (ICR) caloric restriction on serum adiponectin and leptin levels was investigated in relation to mammary tumorigenesis. 10-wks old MMTV-TGF-a female mice were assigned to ad libitum fed (AL; AIN-93M diet), ICR (3-week 50% caloric restriction, AIN-93M-mod diet, 2Â protein, fat, vitamins, and minerals followed by 3-wks 100% AL consumption of AIN-93M), and CCR (calorie and nutrient intake matched for each 6-wks ICR cycle, 75% of AL) groups. Mice were sacrificed at 79 (end of restriction) or 82 (end of refeeding) wks of age. Serum was obtained in cycles 1, 3, 5, 8, 11, and terminal. Mammary tumor incidence was 71.0%, 35.4%, and 9.1% for AL, CCR, and ICR mice, respectively. Serum adiponectin levels were similar among groups with no impact of either CCR or ICR. Serum leptin level rose in AL mice with increasing age but was significantly reduced by long-term CCR and ICR. The ICR protocol was also associated with an elevated adiponectin/leptin ratio. In addition, ICR- restricted mice had increased mammary tissue AdipoR1 expression and decreased leptin and ObRb expression compared with AL mice. Mammary fat pads from tumor-free ICR-mice had higher adiponectin expression than AL and CCR mice whereas all tumor-bearing mice had weak adiponectin signal in mammary fat pad. -
Effects of Chronic Vs. Intermittent Calorie Restriction on Mammary Tumor Incidence and Serum Adiponectin and Leptin Levels in MMTV-TGF-Α Mice at Different Ages
ONCOLOGY LETTERS 1: 167-176, 2010 167 Effects of chronic vs. intermittent calorie restriction on mammary tumor incidence and serum adiponectin and leptin levels in MMTV-TGF-α mice at different ages SONER DOGAN1, OLGA P. ROGOZINA1, ANNA E. LOKSHIN2, JOSEPH P. GRANDE3 and MARGOT P. CLEARY1 1Hormel Institute, University of Minnesota, Austin, MN 55912; 2University of Pittsburgh Cancer Institute, Hillman Cancer Centre Research Pavillion, Pittsburgh, PA 15213; 3Department of Pathology and Laboratory Medicine, Mayo Foundation, Rochester, MN 55905, USA Received January 28, 2009; Accepted July 31, 2009 DOI: 10.3892/ol_00000031 Abstract. Calorie restriction prevents mammary tumor (MT) was significantly reduced as mice aged, but this ratio in ICR development in rodents. Usually, chronic calorie restriction mice was significantly higher than that forad libitum and CCR (CCR) has been implemented. In contrast, intermittent calorie mice. No correlation was noted between serum adiponectin restriction (ICR) has been less frequently used. Recent studies and leptin. These findings demonstrate that intermittent calorie indicate that when a direct comparison of the same degree restriction delays the early development of MTs. This delay of CCR vs. ICR was made using MMTV-TGF-α mice which was associated with reduced serum leptin levels following the develop MTs in the second year of life, ICR provided greater restriction phases of the protocol. Additionally, serum leptin protection than CCR in delaying MT detection and reducing levels correlated with body weight and body fat in the groups tumor incidence. Adiponectin and leptin are two adipocyto- studied. kines secreted from adipose tissue which have opposite effects on many physiological functions, including proliferation of Introduction human breast cancer cells. -
Of Becoming and Remaining Vegetarian
Wang, Yahong (2020) Vegetarians in modern Beijing: food, identity and body techniques in everyday experience. PhD thesis. http://theses.gla.ac.uk/77857/ Copyright and moral rights for this work are retained by the author A copy can be downloaded for personal non-commercial research or study, without prior permission or charge This work cannot be reproduced or quoted extensively from without first obtaining permission in writing from the author The content must not be changed in any way or sold commercially in any format or medium without the formal permission of the author When referring to this work, full bibliographic details including the author, title, awarding institution and date of the thesis must be given Enlighten: Theses https://theses.gla.ac.uk/ [email protected] Vegetarians in modern Beijing: Food, identity and body techniques in everyday experience Yahong Wang B.A., M.A. Submitted in fulfilment of the requirements for the Degree of Doctor of Philosophy School of Social and Political Sciences College of Social Sciences University of Glasgow March 2019 1 Abstract This study investigates how self-defined vegetarians in modern Beijing construct their identity through everyday experience in the hope that it may contribute to a better understanding of the development of individuality and self-identity in Chinese society in a post-traditional order, and also contribute to understanding the development of the vegetarian movement in a non-‘Western’ context. It is perhaps the first scholarly attempt to study the vegetarian community in China that does not treat it as an Oriental phenomenon isolated from any outside influence. -
The Dot Study
LIFESTYLE INTERVENTIONS FOR NON-ALCOHOLIC FATTY LIVER DISEASE Kirsten Coppell, Public Health Physician Senior Research Fellow, Department of Medicine, University of Otago; Training Programme Supervisor, NZCPHM Principles of Healthy Eating In 9 words….. • Eat less • Move more • Eat mostly fruits and vegetables For additional clarification – a 5 word modifier…… • Go easy on junk foods Nestle, Marion (2006). What to Eat. New York: North Point Press (Farrar, Straus and Giroux). ISBN 978-0-86547-738-4. HOW? How much does weight loss surgery cost? Weight Loss Surgery Fees Initial Consultation $280 Gastric Banding Surgery $18,500 Gastric Sleeve Surgery $20,750 Gastric Bypass Surgery $23,500 Additional Fees The Optifast pre-surgery meal replacement diet must be purchased separately from your local pharmacy. Other additional costs may include staying extra nights in hospital, extra theatre time, blood transfusion and/or x-rays. PLEASE NOTE: 99% of patients do not incur additional costs. Based on these costs……… To provide BS for 192,000 210,000 with BMI ≥40kg/m2 @ $20,000 per operation = $3,840,000,000 $4,200,000,000 $74.46M PHARMAC 2017 Year in Review 570,000 PHARMAC 2016 Year in Review The prevalence of overweight and obesity in NZ adults by age group, 2016/17. 100 Overweight Obesity 90 80 70 60 39.3 32.4 37.2 38.4 27.0 50 31.1 40 24.0 30 14.7 Proportion (%)Proportion 12.3 20 10 0 0-14 15-17 18-24 25-34 35-44 45-54 55-64 65-74 75+ Age Groups Ministry of Health. -
Diet Manual for Long-Term Care Residents 2014 Revision
1 Diet Manual for Long-Term Care Residents 2014 Revision The Office of Health Care Quality is pleased to release the latest revision of the Diet Manual for Long-Term Care Residents. This manual is a premier publication—serving as a resource for providers, health care facilities, caregivers and families across the nation. In long-term care facilities, meeting nutritional requirements is not as easy as it sounds. It is important to provide a wide variety of food choices that satisfy each resident’s physical, ethnic, cultural, and social needs and preferences. These considerations could last for months or even years. Effective nutritional planning, as well as service of attractive, tasty, well-prepared food can greatly enhance the quality of life for long-term care residents. The Diet Manual for Long Term Care Residents was conceived and developed to provide guidance and assistance to nursing home personnel. It has also been used successfully in community health programs, chronic rehabilitation, and assisted living programs. It serves as a guide in prescribing diets, an aid in planning regular and therapeutic diet menus, and as a reference for developing recipes and preparing diets. The publication is not intended to be a nutrition-care manual or a substitute for individualized judgment of a qualified professional. Also included, is an appendix that contains valuable information to assess residents’ nutritional status. On behalf of the entire OHCQ agency, I would like to thank the nutrition experts who volunteered countless hours to produce this valuable tool. We also appreciate Beth Bremner and Cheryl Cook for typing the manual. -
Review of the China Study
FACT SHEET REVIEW OF THE CHINA STUDY By Team, General Conference Nutrition Council In 1905 Ellen White described the diet our Creator chose for us as a balanced plant-based diet including foods such as grains, fruit and vegetables, and nuts (1). Such a diet provides physical and mental vigor and endurance. She also recognized that such a diet may need to be adjusted according to the season, the climate, occupation, individual tolerance, and what foods are locally available (2). The General Conference Nutrition Council (GCNC) therefore recommends the consumption of a balanced vegetarian diet consisting of a rich variety of plant-based foods. Wherever possible those should be whole foods. Thousands of peer-reviewed research papers have been published over the last seven decades validating a balanced vegetarian eating plan. With so much support for our advocacy of vegetarian nutrition we have no need to fortify our well-founded position with popular anecdotal information or flawed science just because it agrees with what we believe. The methods used to arrive at a conclusion are very important as they determine the validity of the conclusion. We must demonstrate careful, transparent integrity at every turn in formulating a sound rationale to support our health message. It is with this in mind that we have carefully reviewed the book, The China Study (3). This book, published in 2004, was written by T. Colin Campbell, PhD, an emeritus professor of Nutritional Biochemistry at Cornell University and the author of over 300 research papers. In it Campbell describes his personal journey to a plants-only diet. -
Vegetarian Nutrition Resource List April 2008
Vegetarian Nutrition Resource List April 2008 This publication is a compilation of resources on vegetarian nutrition. The resources are in a variety of information formats: articles, pamphlets, books and full-text materials on the World Wide Web. Resources chosen provide information on many aspects of vegetarian nutrition. Materials included in this list may also be available to borrow from the National Agricultural Library (NAL). Lending and copy service information is provided at the end of this document. If you are not eligible for direct borrowing privileges, check with your local library on how to borrow through interlibrary loan. Materials cannot be purchased from NAL. Contact information is provided if you wish to purchase any materials on this list. This Resource List is available from the Food and Nutrition Information Center’s (FNIC) Web site at: http://www.nal.usda.gov/fnic/pubs/bibs/gen/vegetarian.pdf. A complete list of FNIC publications can be found at http://www.nal.usda.gov/fnic/resource_lists.shtml. Table of Contents: A. General Information on Vegetarian Nutrition 1. Articles and Pamphlets 2. Books 3. Magazines and Newsletters 4. Web Resources B. Vegetarian Diets and Disease Prevention and Treatment 1. Articles and Pamphlets 2. Books 3. Web Resources C. Vegetarian Diets for Special Populations 1. Vegetarianism During the Lifecycle a. Resources for Pregnancy and Lactation b. Resources for Infants and Children c. Resources for Adolescents d. Resources for Older Americans e. Resources for Athletes D. Vegetarian Cooking and Foods 1. Books 2. Web Resources E. Resource Centers A. General Information on Vegetarian Nutrition 1. Articles and Pamphlets Vegetarian Nutrition Dietetic Practice Group Newsletter Full Text: http://www.andrews.edu/NUFS/vndpg.html Description: 18 articles from the Vegetarian Nutrition DPG Newsletter on many aspects of vegetarianism including articles on various diseases, education and essential nutrients. -
ELIMINATION DIET Comprehensive Guide
ELIMINATION DIET Comprehensive Guide Version 10 Table of Contents Why the Elimination Diet? ............... 3 Features of the Elimination Diet ...... 4 Touring Through the Food Plan ....... 8 The Reintroduction Process .......... 14 Helpful Hints .................................. 16 Frequently Asked Questions ......... 17 Resources and Tools for Success .. 19 © 2021 The Institute for Functional Medicine Why the Elimination Diet? Health concerns that have failed to respond to other treatments may improve after completing IFM’s Elimination Diet. Specific foods may be related to a long list of health conditions, including digestive problems, headaches, chronic sinus drainage, low energy, depression, mood swings, eczema, skin irritations, joint aches, asthma, weight gain, and others. Many suffer from these symptoms for long periods of time without realizing the connection to food. It isn’t until a food is eliminated from the diet, that the connection with symptoms can be made. IFM’s Elimination Diet firstly removes common food triggers, then helps you identify specific foods that may be causing ongoing symptoms through a personalized food reintroduction. After the three-week elimination period, a personalized food reintroduction is the next step. Reintroduction involves adding back one food at a time to observe whether that food causes symptoms. Foods that continue to cause symptoms (physical, mental, or emotional) are avoided for an additional three to six months, then reintroduction is attempted again. Once the body has healed, some foods which initially caused symptoms may be tolerated and added back into the diet. The Elimination Diet is a short-term food plan. Healing the gut and being able to eat a wide variety of whole foods are the ultimate goals of the Elimination Diet. -
T. Colin Campbell, Ph.D. Thomas M. Campbell II
"Everyone in the field of nutrition science stands on the shoulders of Dr. Campbell, who is one of the giants in the field. This is one of the most important books about nutrition ever written - reading it may save your life." - Dean Ornish, MD THE MOST COMPREHENSIVE STUDY OF NUTRITION EVER CONDUCTED --THE-- STARTLING IMPLICATIONS FOR DIET, WEIGHT Loss AND LONG-TERM HEALTH T. COLIN CAMPBELL, PHD AND THOMAS M. CAMPBELL II FOREWORD BY JOHN ROBBINS, AUTHOR, DIET FOR A NEW AMERICA PRAISE FOR THE CHINA STUDY "The China Study gives critical, life-saving nutritional information for ev ery health-seeker in America. But it is much more; Dr. Campbell's expose of the research and medical establishment makes this book a fascinating read and one that could change the future for all of us. Every health care provider and researcher in the world must read it." -JOEl FUHRMAN, M.D. Author of the Best-Selling Book, Eat To Live . ', "Backed by well-documented, peer-reviewed studies and overwhelming statistics the case for a vegetarian diet as a foundation for a healthy life t style has never been stronger." -BRADLY SAUL, OrganicAthlete.com "The China Study is the most important book on nutrition and health to come out in the last seventy-five years. Everyone should read it, and it should be the model for all nutrition programs taught at universities, The reading is engrossing if not astounding. The science is conclusive. Dr. Campbells integrity and commitment to truthful nutrition education shine through." -DAVID KLEIN, PublisherlEditor Living Nutrition MagaZine "The China Study describes a monumental survey of diet and death rates from cancer in more than 2,400 Chinese counties and the equally monu mental efforts to explore its Significance and implications for nutrition and health. -
Does a Vegan Diet Contribute to Prevention Or Maintenance of Diseases? Malia K
Cedarville University DigitalCommons@Cedarville Kinesiology and Allied Health Senior Research Department of Kinesiology and Allied Health Projects Fall 11-14-2018 Does a Vegan Diet Contribute to Prevention or Maintenance of Diseases? Malia K. Burkholder Cedarville University, [email protected] Danae A. Fields Cedarville University, [email protected] Follow this and additional works at: https://digitalcommons.cedarville.edu/ kinesiology_and_allied_health_senior_projects Part of the Kinesiology Commons, and the Public Health Commons Recommended Citation Burkholder, Malia K. and Fields, Danae A., "Does a Vegan Diet Contribute to Prevention or Maintenance of Diseases?" (2018). Kinesiology and Allied Health Senior Research Projects. 6. https://digitalcommons.cedarville.edu/kinesiology_and_allied_health_senior_projects/6 This Senior Research Project is brought to you for free and open access by DigitalCommons@Cedarville, a service of the Centennial Library. It has been accepted for inclusion in Kinesiology and Allied Health Senior Research Projects by an authorized administrator of DigitalCommons@Cedarville. For more information, please contact [email protected]. Running head: THE VEGAN DIET AND DISEASES Does a vegan diet contribute to prevention or maintenance of diseases? Malia Burkholder Danae Fields Cedarville University THE VEGAN DIET AND DISEASES 2 Does a vegan diet contribute to prevention or maintenance of diseases? What is the Vegan Diet? The idea of following a vegan diet for better health has been a debated topic for years. Vegan diets have been rising in popularity the past decade or so. Many movie stars and singers have joined the vegan movement. As a result, more and more research has been conducted on the benefits of a vegan diet. In this article we will look at how a vegan diet may contribute to prevention or maintenance of certain diseases such as cancer, diabetes, weight loss, gastrointestinal issues, and heart disease. -
Vegetarian Journal's 25Th Anniversary Issue
Cruelty-Free Businesses Still Going Strong Today 3 O N , I V X X E M U L O V VEGETARIAN J O U R N A L HEALTH ECOLOGY ETHICS What Do Longtime Happy Silver Leaders of the Anniversary, Vegetarian Movement Think the Next 25 Years VRG! Colossal Chocolate Cake with Will Bring? Chocolate Ganache (page 32) $4.50 USA/$5.50 CANADA g r o . 25 Wonderful g r v . w w w Vegan Cuisines! NUTRITION HOTLINE QUESTION: “My 10-year-old grand- In addition, your daughter might REED MANGELS, PhD, RD daughter has decided to become a like some resources on vegetarian- vegetarian. My daughter says she ism. VRG’s website has a section doesn’t know what to feed her and on vegetarian children and teens. says she is mainly eating cheese and Your granddaughter and her par- now is not eating veggies or fruits. ents may find it helpful to meet My granddaughter keeps saying with a dietitian who is knowledge- she is hungry all the time.” able about vegetarian diets and A.V., via e-mail can do nutrition education while helping them develop meal ideas. ANSWER: Here are some sugges- tions you may want to pass on QUESTION: “I was wondering if to your daughter. It’s important my being a vegan would affect the for your granddaughter to be health of my daughter who is 11 aware that it’s her responsibility months old and is still nursing. (with the help of her parents) to She is on the small side, but I am choose a variety of healthy vege- only 4' 10". -
Change Your Diet, Go Plant Based 3 1
go plant based International Society for Cow Protection ISCOWP.ORG Radhika and Devaki on front cover. Priya, in the photo above, is the king of the ISCOWP herd. International Society for Cow Protection ISCOWP Profile Dear Friends, The International Society for Cow Protection, Inc. (ISCOWP) was incorporated in the USA, We believe that rescuing cows from being sold March 1990, as a 501 (c) (3) non-profit, tax for meat and then caring for them their entire exempt organization. William and Irene Dove lives (a cow can live for 25 years or more) until (Balabhadra das and Chayadevi dasi) are its their natural death is a humane, compassionate managing directors. They are disciples of His Divine Grace A.C. Bhaktivedanta Swami act and can only help the planet towards a more Prabhupada, the Founder Acharya of the Inter- peaceful existence. national Society for Krishna Consciousness (ISKCON). Through their spiritual master's Besides having our local sanctuary we teachings, they have imbibed the practices and encourage and educate others how they too can benefits, both spiritual and material, of lifetime care for cows. William E. Dove, ISCOWP cow protection. Cow protection means enabling president, has traveled widely to counsel future cows to live out their natural lives with love and and current cow protection programs. We also affection. The tenets of cow protection are offer assistance through conference calls, universal and nonsectarian, available to all seminars and literature. regardless of race, creed, or nationality. Mailing Address ISCOWP Compared to the numbers of cows bred 7016 SE 92 Terrace worldwide each day, what we are doing, both Gainesville FL, USA, 32641 locally and beyond, is less than a mere drop in Phone the bucket.