P ROGRAM

The TERMIS-Americas 2013 Annual Conference & Exposition

CELEBRATING 25 YEARS

OF TRANSFORMATIVE g/am201 3 SCIENCE & ENGINEERING .termis.o r

November 10-13, 2013 ww w Hyatt Regency Atlanta Atlanta, Georgia Hosted by: TABLE of CONTENTS Welcome …. 4

General Information …. 5

Bench to Business Workshop …. 6

Women in TERM Luncheon …. 7

Opening Symposium …. 8

Opening Day Schedule Sunday, November 10 …. 9

Podium Presentations Monday, November 11 …. 10 - 14

Podium Presentations Tuesday, November 12 …. 15 - 18

Podium Presentations Wednesday, November 13 …. 19 - 24

Poster Session I Monday, November 11 …. 25 - 32

Poster Session II Tuesday, November 12 …. 33 - 41

Student & Young Investigator Section Welcome & Activities …. 43 - 44

Student Poster Competition …. 45

WFIRM YIA Award Winners …. 46

TERMIS-AM 2013 Award Winners …. 47 - 48

Exhibitor Floorplan and Listing …. 49 - 52

Sponsors …. 53 - 54 OPENING RECEPTION Hosted by the Exhibitors and Sponsors Sunday, November 10, 2013 7:00 - 9:00 PM Located in the Regency Ballroom 3 4

Welcome Sincerely,

we encourage you tocelebrate thisweekwithusandenjoy the25 advisory committees, trainees and attendees, to build a healthy and vibrant society and for that reason, has beenover ayear inthemaking,successofthisyear’s meeting reflectstheeffortsofpast chairs, We arevery proudtohostthe TERMIS-AM 2013meetingandwelcomeyou toourcity. Although it Institure of Technology Parker H.Petit InstituteforBioengineering andBioscience. dinner andreceptiontobeheld Tuesday evening atthe World ofCoca-Cola,hostedby Georgia Finally, addition, theyhave organizedthefirst-ever localareahighschool outreach event. year, including doublingthenumbersofparticipantsMentoringLunch andCareerPanel. In support fromtheNationalScienceFoundation, wewereabletoexpandmany oftheSYISevents this the Americas chapter (SYIS-AM)hasorganizedanumberofexcitingactivities atthemeeting. With Realizing theimportanceofastrongtrainee network, theStudentand Young Investigator Sectionof Facility, CincinnatiChildren’s HospitalMedicalCenter. Chair inRegenerative MedicineandPerinatal Endocrinology andDirector, PluripotentStemCell and Tissue Regeneration, University ofCalifornia,SanFrancisco; andJames M. Wells, PhD Departments ofSurgeryandBioengineering Therapeutics, andDirector, CenterforBioengineering the RoddenberryStemCellCenteratGladstone; MD impact newtissueengineeringandregenerative medicinestrategies, includingDeepakSrivastava, We willhearfromdistinguishedkeynotelecturersspeakingaboutinnovative approaches that of sessionsdedicatedtoclinicaltranslational work. research themesthatbroadlyimpactdifferenttissueandorgansystems,wehave alsoincludedaseries tissue engineeringandregenerative medicine.Inadditiontoemphasizingbasicandappliedscientific the fundamentalprinciples,emergingstrategies, andpractical applicationsofthelatestadvances in We arevery excitedaboutthisyear’s scientificprogram comprisedofsessiontopicsthatfocuson Institutes ofHealthandNationalScienceFoundation. existing outreach andtraining opportunitieswillbesupportedinpartby grants fromtheNational luncheon, andasessionfocusedonpublicpolicy. These newactivities aswellenhancementof the firstever TERMIS-AMconferencedinner, a Women in & community. As aresult,wehave addedseveral newandexcitingelementstotheprogram, including 200 oral presentationsand 400poster-acleartestamenttothecontinuedgrowth ofthis record-breaking attendanceofover 1,000. Planning forthe2013 TERMIS-AM Conferencehasbeenagreatsuccess,reflected by ananticipated evolved over thepast25years, aswellshareinsightsonfuturedirectionsofthefield. symposium onSunday willprovide talksfromseveral leadersonhow keyareas ofthefieldhave was inspiredby thefirstfederally fundedtissueengineering workshop in1998. The openingplenary The themeofthisyear’s meeting,“Celebrating 25years of Transformative Science&Engineering,” to personallywelcomeyou to Atlanta, Georgia. everyone involved insupportingthe TERMIS-Americas (TERMIS-AM)2013Conference,wewould like On behalfofthescientificadvisory committee, theinternationalcommunityof TERMIS members,and FellowAttendees: TERMIS Dear November 10,2013

Georgia Institute of Technology Mechanical Engineering Professor, George W. Woodruff School of for BioengineeringandBioscience, Executive DirectoroftheParker H.Petit Institute TERMIS-AM 2013Conference Chair Robert E.Guldberg,PhD , Younger DirectoroftheGladstoneInstituteCardiovascular DiseaseandDirectorof conference guestsareinvited toanevening offunandcelebration attheconferencegala We received over 600abstracts, resultinginapproximately

Valerie M. Weaver, PhD Georgia Institute of Technology and EmoryUniversity of Biomedical Engineering Associate Professor, Wallace H.Coulter Department of TechnologyInstitute Director, Stem CellEngineeringCenter, Georgia Bioengineering andBioscience Petit Faculty Fellow, Parker H.Petit Institutefor TERMIS-AM 2013ScientificProgram Chair Todd C.McDevitt,PhD

th anniversary ofourfield’s birth! , Associate Professor,, Associate

, Endowed , Endowed

OPENING RECEPTION ONSITE REGISTRATIONANDCONFERENCE CHECK-IN SCIENTIFIC ADVISORYCOMMITTEE GENERAL INFORMATION The registration deskwillbeopenat the following times: Photo IDisrequiredatcheck-in. Jennifer West, PhD, DukeUniversity Ned Waller, PhD, MD, EmoryUniversity Johnna Temenoff, PhD, GeorgiaInstituteof Technology Michael Sefton,ScD, University of Toronto InterfacialEngineeringandBiotechnology IGB Katja Schenke-Layland, PhD, Fraunhofer Institutefor Shelly Sakiyama-Elbert, PhD, Washington University Abhay Pandit, PhD, NationalUniversity ofIreland Sean Palecek, PhD, University of Wisconsin William Murphy, PhD, University of Wisconsin Antonios Mikos,PhD, RiceUniversity Alison McGuigan,PhD, University of Toronto Masahiro Kino-Oka,PhD, OsakaUniversity Gilson Khang,PhD, ChonbukNationalUniversity Dietmar Hutmacher, PhD, QueenslandUniversity of Technology Sarah Heilshorn,PhD, StanfordUniversity Sharon Gerecht, PhD, Johns HopkinsUniversity Andrés García, PhD, GeorgiaInstituteof Technology John Fisher, PhD, University ofMaryland Jennifer Elisseeff,PhD, Johns HopkinsUniversity Robert Christy, PhD, UnitedStates Army InstituteofSurgicalResearch Jason Burdick, PhD, University ofPennsylvania Mário Barbosa,PhD, INEB Dolores Baksh,PhD, Organogenesis Stephen Badylak, PhD, MD, University ofPittsburgh Scientific ProgramChair Todd McDevitt,PhD,GeorgiaInstituteofTechnology, Conference ChairandTERMIS-AMChapter Robert Guldberg,PhD,GeorgiaInstituteofTechnology, • ExhibitHall –Regency Ballroom • 7:00PM- 9:00PM • Sunday, November 10,2013 • Wednesday, November 13from7:00 AM –5:00PM • Tuesday, November 12from7:00 AM –5:00PM • Monday, November 11from7:00 AM –5:00PM • Sunday, November 10from7:00 AM –7:00PM 5 PRECONFERENCE WORKSHOP • SUNDAY, NOVEMBER 10, 2013 • 8:00AM – 2:00PM WOMEN IN TISSUE ENGINEERING AND REGENERATIVE MEDICINE LUNCHEON

Bench to Business Workshop “Avoiding Traps” Organized by the TERMIS-AM Industry Committee Sunday, November 10th from 11:30 AM - 2:00 PM

This workshop will feature experienced speakers working directly on the challenges associated with Registration for the event is FREE. The maximum number of attendees for the technology transfer for the commercialization of academic research. Topics will include designing Women in TERM Luncheon is 100, so registrations will be awarded on product development studies to facilitate industrial interest, translation and commercialization, a first-come first-serve basis. developing and protecting commercially-relevant intellectual property, working with university technology transfer offices, partnering with existing companies including biotechnology and Invited Discussants: establish corporate entities, developing a business plan and attracting funding to support Gordana Vunjak-Novakovic, Columbia University commercialization of the academic technology. Attendees will benefit from real-world case studies, Molly Shoichet, University of Toronto practical examples and guidance from experienced thought leaders. The goal of the workshop is Bob Nerem, Georgia Institute of Technology for attendees to leave with actionable concepts of how to evaluate their current research enterprise Michael Sefto, University of Toronto for technology and start the process toward potential commercialization. The knowledge and tools Milica Radisic, University of Toronto gained from the workshop is anticipated to represent successful approaches used to accelerate the Shelley Sakayama-Elbert, Washington University commercialization of your research efforts. Alison McGuigan, University of Toronto Katja Schenke-Layland, University Women’s Hospital Tübingen Registration fee: $99.00 Research efforts in tissue engineering have intensified in the past 25 years, coinciding with the increased efforts to promote enrollment of female students in all areas of engineering. Agenda: As tissue and biomedical engineers, we have been successful in recruiting female students into our undergraduate and graduate programs. More than 50% of PhD degrees are 8:00 AM to 8:15 AM Opening Remarks awarded each year to female students in areas of Engineering and Life sciences. Majority Tim Bertram (~60%) of NSF and NIH pre-doctoral awards are awarded to female students, however only 20-30% of junior faculty awards are awarded to female faculty (NSF and NIH 8:15 AM to 9:15 AM Directing Academic Research toward Commercializable Accountability Report 2008). Therefore, some of our best students are lost as they progress Technologies through the academic ranks for issues other than performance or ability. Enabling them to H. Lee Herron realize full potential of their careers will be beneficial for the development of the emerging 9:15 AM to 10:15 AM Strategies for IP Protection and Business Development fields of tissue engineering and regenerative medicine. Christopher Jeffers At the 2013 TERMIS-AM we will organize the first ever Women in TERM Luncheon with 10:15 AM to 10:30 AM Break the purpose of fostering support and professional development of young women in our field. We are the first TERMIS continental chapter to organize such an event. We hope we 10:30 AM to 11:30 AM Funding a Startup, Developing the Business, Exit Strategies will be able to transfer our best practices to our sister continental chapters in Europe and Cory Anderson Asia-Pacific. We have gathered a group of leading tissue engineering and regenerative medicine researchers who are willing to support this event. Our diverse group includes 11:30 AM to 12:45 PM Lunch women at different stages of career development: established, mid-career and pre-tenure, as well as senior researchers who have supported career developments of young scientists in the past three decades (Sefton, Nerem). Each speaker was asked to spend 5-10 minutes 12:45 PM to 1:45 PM Working with Large Companies as Partners or Exit Strategies presenting what they perceive major issues/solutions are to avoiding traps in female career Cheryl Blanchard development with the remaining time spent actively engaged in discussions/questions from the audience. 1:45 PM to 2:00 PM Closing Remarks Tim Bertram

6 7 TERMIS-AM OPENING SYMPOSIUM - SUNDAY, NOVEMBER 10, 2013 DAY 1 - SUNDAY, NOVEMBER 10, 2013

Tissue Engineering and Regenerative Medicine: Origins and Its Evolution Chair: Bob Nerem, Georgia Institute of Technology

Registration for the Opening Symposium is included in your conference registration. The opening symposium “Tissue Engineering & Regenerative Medicine: Origins and its Evolution” will gather past, present and future leaders to mark this important 25-year milestone since the first federally-funded tissue engineering meeting held at Granlibakken, Lake Tahoe, California in February 1988. As the field of tissue engineering and regenerative medicine has evolved over the years, resulting in groundbreaking medical science discoveries, it is important to revisit the discipline’s history and lessons learned in order to guide the future of this ever-expanding, multidisciplinary field. Special recognition will also be given to the major pioneering leaders of the field and their important contributions. The symposium will be of great value to trainees and young investigators who will TERMIS-AM Industry Committee: Bench to Business Workshop gain a better understanding and appreciation for tissue engineering and regenerative medicine as 8:00 AM - 2:00 PM a research discipline. Hanover CD Introduction to the History of Tissue Engineering & 2:00 PM Bob Nerem Regenerative Medicine 2:20 PM and Regenerative Medicine Michael Sefton 11:30 AM - 2:00 PM Women in TERM Luncheon Hanover FG The Role of Biomechanics in the Evolution of 2:45 PM David Butler Regenerative Medicine Impact of Stem Cells on the Evolution of Tissue 3:10 PM Jane Lebkowski Engineering & Regenerative Medicine 12:00 PM - 2:00 PM SYIS-AM Lab & Campus Tours 4:00 PM Break

4:25 PM Emergence of Industry Geoff McKay Tissue Engineering & Regenerative Medicine: Origins & Evolution 2:00 PM - 6:30 PM 4:50 PM Clinical Need and Healthcare Impact of Tissue Engineering Christopher Breuer Centennial III & IV Federal Government Support of Tissue Engineering and 5:15 PM Christine Kelley Regenerative Medicine: Past, Present, and Future 5:40 PM Panel Discussion on Future Directions Kristi Anseth 7:00 PM - 9:00 PM Opening Reception Regency Ballroom Anthony Atala Robert Deans Andrés Garciá David Mooney 6:30 PM Adjourn & Welcome Reception

8 9 DAY 2 - MONDAY, NOVEMBER 11, 2013 DAY 2 - MONDAY, NOVEMBER 11, 2013

8:00 AM Welcome Announcement - Centennial III & IV Meeting Centennial I Centennial II Centennial III Centennial IV Room 8:05 AM Keynote Speaker I - James Wells - Centennial III & IV 10:45 - Roshan James Young Wook Chun Andrew Khalil James Henstock 9:00 AM Lifetime Achievement - Bob Nerem - Georgia Institute of Technology 11:00 AM The University of Vanderbilt University University of Wisconsin- Keele University 9:30 AM Coffee Break with Poster Viewing - Regency Ballroom Connecticut Health Madison Session I: Biomaterials Cell Responses to Drug Delivery Mechano-transduction Center Regulation of Engineered Matrices Principles Achilles Tendon Maturation of Optimized Inorganic Remote Controlled 10:00- Morphogen Regeneration Using Human iPSC-derived Coatings of Mechnotransduction 11:30 AM Presentation a Bioresorbable Cardiomyocytes Microparticles for Non- Via Magnetic Session Kristyn Masters Andrés Garciá Gilson Khang Adam Engler Biomimetic Scaffold, on Combinatorial Viral Transfection of Nanoparticles Chairs Stem Cells and Growth Polymer Fiber Matrix Aggregates Promotes Osteogenesis; Factor Composite Applications for Johnna Temenoff Brendan Harley Elizabeth Loboa Brent Hoffman Injectable Cell Therapy Student Minh Khanh Nguyen Adam Taylor Alexander Baume Merlin Rajesh Lal L P 11:00 - Rene Olivares-Navarrete Amr Abdeen Jaclyn Obermeyer Tom Bongiorno Co-Chair 11:15 AM Virginia Commonwealth University of Illinois at University of Toronto Georgia Institute of Meeting Centennial I Centennial II Centennial III Centennial IV Room University Urbana Champaign Technology Wnt and BMP Mesenchymal Stem Minimally Invasive Mechanical Stiffness 10:00 - Bill Murphy Kyung Min Park Brian Evans Adam Engler 10:15 AM Signaling Molecules Cell Angiogenic Delivery of Brain- as an Indicator of University of Wisconsin The Johns Hopkins Vanderbilt University University of California are Affected Potential depends on Derived Neurotrophic Osteoblastic Human University San Diego by Osteogenic Extracellular Matrix Factor to the Brain Bioinspired Hypoxia-Inducible MK2 Inhibitory Nano- High Throghput Induction Medium in Composition and Differentiation Morphogen Regulation Hydrogels for Polyplexes Prevent Assessment of Focal Osteogenesis In Vitro Stiffness in the Stem Cell Regenerative Intimal Hyperplasia Ex Adhesion-Based 11:15 - Laxminarayanan Neil Davies Shalini Saxena Jeffrey Jacot Microenvironment Medicine Vivo in Human Vein Mechanotransduction 11:30 AM Krishnan and In Vivo in a Rabbit Candidates Transplant Model Georgia Institute of University of Cape Georgia Institute of Rice University Technology Town Technology 10:15 - Jennifer Bain Alison Douglas Song Seto Vincent Fiore 10:30 AM Is Alginate-based BMP- Cell Type Raspberry- Liquid Crystal University of Alabama at Georgia Institute of Georgia Institute of Georgia Institute of 2 Delivery a Viable Specific Invasion Structured Microgel Elastomers for Strain Birmingham Technology Technology Technology Alternative to Current of Hydrogels Heteroaggregates Conditioning of BMP2 Mimetic Peptide Incorporation of Tuning the Thy-1 Regulates Clinical Treatments for Polymerised with for Encapsulation Cardiomyocytes Anchored to Bone pNIPAM Microgels Interactions of Soluble Lung Fibroblast Large Bone Defects? Different Matrix and Delivery of Graft Materials Via a into Fibrin Matrices Protein:Heparin Mechanotransduction Metalloproteinase Morphogens Specific Bone Binding for Enhanced Cell Complexes with GAG- of Extracellular Matrix Cleavage Sites Domain Enhances Infiltration and based Hydrogels Stiffness 11:30 AM Lunch Break with Poster Viewing - Regency Ballroom Osteoinductivity Wound Healing 11:30 AM Student Career Panel - The Learning Center 10:30 - Marian Hettiaratchi Alex Laperle Daniel Lynam Leah Pagnozzi 10:45 AM 11:30 AM TERMIS-AM Council Meeting with Lunch - EC Suite 219 2nd Floor of Atrium Tower Georgia Institute of University of Michigan State University Cornell University Session II: Composite & Spatially Engineering Engineering Engineering Tissues In Technology Wisconsin-Madison 1:00 - Engineered Materials Matrices for Tissue Morphogenic Vitro for Screening & Controlled Human Pluripotent Controlled Brain Cyclic Anisotropic 2:30 PM Regeneration Environments Diagnostics Presentation of Stem Cells Produce Derived Neurotrophic Strain Mediates Bioactive BMP- ECM that Promotes Factor Release from Myofibroblast Session Ipsita Banerjee Sarah Heilshorn Alison McGuigan James Hickman 2 via Heparin Self-Renewal Layer-by-Layer Coated Differentiation through Chairs Methacrylamide Hydrogel Scaffolds for Activation of SMAD2 Krish Roy Rene Olivares- Bill Murphy Milica Radisic Microparticles Nerve Repair Phosphorylation Navarrete Session: Anthony Melchiorri Joydeep Kundu Samer Zaky Eliza Fong Student Co-Chair

10 11 DAY 2 - MONDAY, NOVEMBER 11, 2013 DAY 2 - MONDAY, NOVEMBER 11, 2013

Meeting Centennial I Centennial II Centennial III Centennial IV Meeting Centennial I Centennial II Centennial III Centennial IV Room Room 1:00 - Brendan Harley Molly Shoichet Jeff Morgan James Hickman 2:15 - Johnna Temenoff Michael Jaeggli Taby Ahsan Lindsay Wray 1:15 PM 2:30 PM University of Illinois at University of Toronto Brown University University of Central Georgia Institute of Clemson University Tulane University Tufts University Urbana-Champaign Florida Technology and Emory Engineering Engineering Micro-Mold Design Low Cost University Coincident Gradations The Cellular Controls the 3D Microphysiological Biomaterials to Assembly and Role of Fibroblasts and Engineering the of Structural and Microenvironment Morphological System with Analytics Enhance Mesenchymal Testing of Tri-layered Mesenchymal Stem Vascular Niche: Biochemical Cues for Evolution of Self- Stem Cell Response to Tissue Engineered Cells in Regulating Development of a Tendon-Bone Junction Assembling Multi- Soluble Cues Heart Valves in Regeneration Processes Basement Membrane Repair Cellular Microtissues Physiologically Model for Studying 1:15 - Michael Hill Guoguang Niu Sebastian Barreto Relevant Conditions Megakaryopoiesis In 1:30 PM Vitro Case Western Reserve Johns Hopkins University University 2:30 PM Break with Poster Viewing - Regency Ballroom Biodegradable Cell-Seeded Gelatin- Novel In Vitro Model Session III: Biomaterials for Reproductive Engineering Integration of ‘omics in Hydrogels Presenting a Based Scaffold for for Microvasculature 3:00 - Cell Delivery & Biology Multicellular Regenerative Medicine Gradient of siRNA for Regenerating the Reveals Regulation 4:30 PM Recruitment Morphogenesis Spatial Control of Cell Corneal Endothelium of Circumferential Gene Expression ECM Organization by Session Elizabeth Lipke Lonnie Shea Taby Ahsan Melissa Kemp Curvature Chairs 1:30 - Lucas Kinard Supansa Yodmuang David Belair Tracy Hookway Cherie Stabler Ariella Shikanov Laura Suggs William Stanford 1:45 PM Rice University Columbia University University of Wisconsin- Georgia Institute of Student Aleksander Skardal Zegbeh Jallah Carlos Kengla Shruti Balaji Madison Technology Co-Chair Oligo(poly(ethylene Silk Fiber-reinforced iPS-Derived Engineering 3D Cardiac 3:00 - Sarah Heilshorn Lonnie Shea Alison McGuigan Marjorie Brand 3:15 PM glycol) fumarate) Hydrogels for Endothelial Cells Microtissues from Stanford University Northwestern University of Toronto Ottawa Hospital Research as a Synthetic Cartilage Tissue Exhibit Sprouting in Human Pluripotent University Institute Hydrogel Carrier for Engineering Synthetic Hydrogel Stem Cells Demineralized Bone Arrays Injectable Matrices for Biomaterials for Generating Robust Trichostatin A Enhances Matrix Delivery of Adipose- Fertility Preservation: Tissue Boundaries the Vascular Repair derived Stem Cells to Early Stage Ovarian to Enable Stable Function of Injected 1:45 - Qiongyu Guo Daniel Puperi Glen Kirkham Monica Moya Heal Critical-size Bone Follicle In Vitro Patterning of an Human Endothelial 2:00 PM Johns Hopkins University Rice University University of Nottingham University of California, Defects Culture and Engineered Tissue In Progenitors by Irvine Transplantation Vitro Increasing TAL1- Dependent Cell Holographic Optical iPS Human Derived 3:15 - Amy Cheng Melissa Kinney Incorporation of Hyaluronan Migration Chondroitin Sulfate Hydrogels for Tweezers as a Tool for Tissues for Patient- 3:30 PM Bioadhesive into Biomimetic the Study of Stem Cell Specific Drug Screening Georgia Institute of Georgia Institute of Bioactive Glasses for Spongiosa Layer of Microenvironments Technology Technology & Emory Repairing Critical Tissue Engineered University Size Bone Defects in Aortic Valve Integrin-Specific Biophysical Properties Rabbits Hydrogels for the of 3D Pluripotent 2:00 - Chris Bashur Shreya Raghavan M.K. Sewell-Loftin Jia-Ling Ruan Delivery of Human Microenvironments 2:15 PM Mesenchymal Stem Regulate Microtissue Cleveland Clinic Wake Forest School of Vanderbilt University University of Washington Cells in Bone Repair Morphogenesis Medicine Composition of Intra- Neuroglial Mechanical Regulation Effect of Mechanical Peritoneal Conduits Differentiation of of Endocardial EMT Strain on Engineered Impacts Phenotype of Enteric Neuronal and Cell Migration on Tissue from Stem Cells- Recruited Cells and Progenitor Cells Collagen-Hyaluronic Derived Progenitors Matrix Generative as a Function of Acid Gels Outcomes Extracellular Matrix Composition in Tissue Engineered Intestinal Constructs

12 13 DAY 2 - MONDAY, NOVEMBER 11, 2013 DAY 3 - TUESDAY, NOVEMBER 12, 2013

Meeting Centennial I Centennial II Centennial III Centennial IV 8:00 AM Welcome Announcement - Centennial III & IV Room 8:05 AM Keynote Speaker II - Deepak Srivastava - Centennial III & IV 3:30 - Vince Beachley Joanna Burdette Cheston Hsiao Jochen Ringe 3:45 PM 9:00 AM Senior Scientist Award - William R. Wagner - University of Pittsburgh Johns Hopkins University University of Illinois at University of Wisconsin- Charité-University Chicago Madison Medicine Berlin 9:15 AM Young Investigator Award - Alison P. McGuigan - University of Toronto Effect of Variable Development of Human Pluripotent Changes in 9:30 AM Coffee Break with Poster Viewing - Regency Ballroom Tissue ECMs on Cell an Ex Vivo Female Stem Cell Culture N-Glycosylation Meeting Centennial I Centennial II Centennial III Centennial IV Function/Behavior Reproductive Density Affects Hippo Profile of Human MSC Room Tract in a 3D Pathway Signaling in During Adipogenic Microphysiologic 2D and 3D Development - Towards Session Non-destructive Cell Reprogramming Engineering of Vascularization of Setting a Next Generation I: 10:00- Phenotype Analysis Scaffold Material Engineered Tissues of Markers for 11:30 AM Properties Regenerative Medicine Session David Kohn Sean Palecek Julie Babensee Sharon Gerecht 3:45 - Guang Yang Pamela Kreeger Laura Geuss Eric James Chairs 4:00 PM University of Pittsburgh University of The University of Texas at University of Connecticut Molly Stevens Shelly Sakiyama-Elbert Elizabeth Cosgriff Wisconsin-Madison Austin Hernandez Tendon-Derived An In Vitro Model Magnetic Attraction of MicroRNA 29a Mimic Student Jialing Ruan Casey Roberts Aline Thomas Bao Nguyen Extracellular Matrix to Analyze Cell- Paramagnetic Beads Loaded Gelatin Co-Chair Enhances Tenogenic Cell Interactions in Influences Lineage Nanofibers as an 10:00 - David Kohn Paul Krebsbach Paul Bonvallet Shulamit Levenberg Differentiation of Endometriosis Commitment in Osteogenic Scaffold for 10:15 AM Human Adipose- Embryoid Bodies Bone Tissue Engineering University of University of Michigan University of Alabama at Technion Derived Stem Michigan Birmingham Cells Cultured in Assessing Spatial Derivation of Microporous Olfactory Bulb-Derived 3-Dimensional Variance in Xenogeneic-free and Electrospun Dermal- Cells Seeded on 3D Collagen Scaffold Collagen Maturity: Transgene-free Human Mimetic Scaffolds Scaffolds Exhibit under Tension Importance of iPSCs on Synthetic Promote Rapid Neurotrophic Factor Tissue History Substrates and Effective Skin Expression and Pro- 4:00 - Ashwin Nair Angela Pannier Angela Xie Richard Carpenedo 4:15 PM Regeneration Angiogenic Properties University of Texas at University of Nebraska- University of Wisconsin- Ottawa Hospital Research 10:15 - Jim De Yoreo John Martin Daphne Hutton Arlington Lincoln Madison Institute 10:30 AM Healing Bone Using The Effect of Soluble Adhesion-dependent Dynamic Gene Pacific Northwest Vanderbilt University Johns Hopkins University Autologous Stem Uterine Factors on Morphogenesis of Regulatory Networks National Laboratory Cell Recruiting Porcine Embryo Human Embryonic Controlling The Energetics In Vivo Performance Effects of Inflammatory and Differentiating Development Within Stem Cells in Patterned Mesendoderm of Collagen- of an ROS-degradable Cytokines on Engineering Scaffolds a Three-Dimensional Chemically Defined Differentiation of Hydroxyapatite Tissue Engineering Vascularized Bone Alginate Matrix Environments Human Embryonic Stem Interactions and Scaffold System Cells its Influence on the Architecture of 4:15 - Harsha Ramaraju Sunyoung Joo Yun Wang Melissa Kemp 4:30 PM Bone University of Michigan Wake Forest University Georgia Institute of Georgia Institute of 10:30 - Liisa Kuhn Brian Diekman Lauren Priddy Anthony Awojoodu Technology Technology 10:45 AM Improving Specificity A Novel Two-Step Skeletal Development Multivariate Analysis in University of Duke University Georgia Institute of Georgia Institute of of MSC Attachment to Strategy to Generate in Tissue Engineering and Connecticut Health Medical Center Technology Technology Biomaterials with Dual Functional Ovarian 3D Aggregates Regenerative Medicine: Center Functioning Phage Follicles Applications and Collagen Type Enhancing the Improved Quality of The Tale of Two Types: Derived Peptides Opportunities I Reporter Regenerative Capacity Regenerated Bone Sphingosine 1-Phosphate Mice: a Tool of Engineered Using Oxidized Receptor Three in the 4:30 - Exhibit Viewing/Reception - Poster Session I Regency Ballroom 6:00 PM for Determining Cartilage by Silencing Alginate Hydrogels Angiocrine Recruitment the Cell Cycle of Anti-Inflammatory 7:00 PM SYIS Reception - See page 44 for details Differentiation Inhibitor p21 Monocytes to Functional Osteoblasts

14 15 DAY 3 - TUESDAY, NOVEMBER 12, 2013 DAY 3 - TUESDAY, NOVEMBER 12, 2013

Meeting Centennial I Centennial II Centennial III Centennial IV Meeting Centennial I Centennial II Centennial III Centennial IV Room Room 10:45 - David Tran Chenyi Pan Anthony Melchiorri Angela Zachman 1:00 - Anand Asthagiri Charles Gersbach Shyam Patel Robert Tranquillo 11:00 AM 1:15 PM University of Georgia Institute of University of Maryland Vanderbilt University Northeastern Duke University University of California, University of Minnesota California, Irvine Technology University Berkeley FLIM Phasor Regulation of H19/ Combinatorial Peptide-functionalized Predicting the Custom Redesign of Enhanced Tissue Aligned Engineered Analysis Igf2 Locus by Insulator Surface Modification Injectable Polymers Evolutionary Tuning the Human Genome Ingrowth with Microvessels with High Characterizes Binding Protein and of a Poly(Glycolic- Regulating Angiogenesis of Developmental with Engineered DNA- Chemical Modification Lumen Density via Metabolic Linker Histones in co-Lactic Acid) and Inflammation in Multicellular Binding Proteins of Poly(Lactide- Cell-Induced Fibrin Maturation of Embryonic Stem Cells - Poly(DL-Lactide- Peripheral Artery Disease Patterns Co-Caprolactone) Gel Compaction and Human iPS-derived co-Caprolactone) Microfibrous Scaffolds Interstitial Cardiomyocytes by Small-Diameter Cardiac-Derived Vascular Graft via 1:15 - Douglas White Ashley Brown Monica Moya 1:30 PM Extracellular Matrix CD34 Antibody and Georgia Institute of Georgia Institute of University of California, VEGF to Enhance Technology Technology Irvine Endothelialization Quantitatively Induction of Fibrin A Dual-Chamber 11:00 - Rameshwar Rao Amanda Smith Ana Gonçalves Eunna Chung Assessing Spatial Gel Contraction by Microfluidic Device 11:15 AM University of Washington University 3B´s Research Group The University of Texas at Patterns of Synthetic Platelets to Study the Role of Michigan in Saint Louis Austin Differentiation for Enhanced Wound Interstitial Flow and Cell- in Aggregates of Healing Cell Contact on Vessel Nondestructive Direct Reprogramming Flow Perfusion and Successful Employment Mouse Embryonic Evaluation of of Mouse Fibroblasts Magnetic Stimulation of PEGylated Fibrin Stem Cells Mineralization to Cardiomyocytes of SPCL Scaffolds Hydrogels to Enhance and Osteoblast Using Yamanaka dopped with Regenerative Actions 1:30 - Elif Bayrak Wan-Ju Li James Pinney Joel Boerckel 1:45 PM Phenotype in Factors on Engineered Nanosized Magnetic of Adipose-derived Illinois Institute of University of Wisconsin- University of California, Cleveland Clinic Engineered Tissues Poly(ethylene glycol) Particles for Tendon Stem Cells for Tissue Technology Madison San Francisco Using Spectral (PEG) Hydrogels Regeneration Engineering Applications Ultrasound Imaging Multi-Agent Model Osteogenesis of Therapeutic MKP-1 Positively of Tissue Growth Human Mesenchymal Microstructures for the Regulates 11:15 - Molly Stevens Shigang Lin Lonnie Shea Abritee Dhal and Vascularization Stem Cells Enhanced Attenuation of Fibrosis Neovascularization 11:30 AM Imperial College University of Western Northwestern University Wake Forest School of in Porous Scaffolds by Osteoprotegerin after Myocardial and Angiogenic Gene London Ontario Medicine through Activation of Infarction Expression Nuclear Factor-kappa State of the Art Activation of Modulation of the Islet Development of an B Materials Analysis Transcription Factor Microenvironment Acellular Porcine of Engineered GAX and Concomitant to Support Islet Liver Approach for Tissue Downregulation of Engraftment and Bioengineering of Livers Il-1β and ERK1/2 Function Using PLG for Transplantation Modulate Vascular Scaffolds Smooth Muscle Cell (VSMC) Phenotype on 3D Fibrous Scaffolds 11:30 AM Lunch Break with Poster Viewing - Regency Ballroom 11:30 AM Student Meet Mentor Lunch - Hanover AB Session II: Computational Cell Engineering Tissue Modulation via Engineering of 1:00 - Modeling Biomaterials Vascularization Strategies 2:30 PM Chairs Roger Kamm Josh Leonard Jan Stegemann Eric Brey Anand Asthagiri Kris Saha Sarah Stabenfeldt Ed Botchwey Student Jean-Michel Bourget Hyunhee Ahn Chan Ho Park Amr Abdeen Co-Chair

16 17 DAY 3 - TUESDAY, NOVEMBER 12, 2013 DAY 4 - WEDNESDAY, NOVEMBER 13, 2013

8:00 AM Welcome Announcement - Centennial III & IV 1:45 - Esmaiel Jabbari Aubrey Tiernan Shanmugasundaram Christopher Nelson 8:05 AM 2:00 PM Natesan Keynote Speaker III - Valerie Weaver - Centennial III & IV 9:00 AM MAL Outstanding Student Award - Rameshwar R. Rao - University of Michigan University of South Georgia Institute of United States Army Vanderbilt University 9:10 AM WFIRM YI Awards Presentations Carolina Technology Institute of Surgical Minh Khanh Nguyen, PhD - Eben Alsberg Laboratory Research Department of Biomedical Engineering Simulation of Development of a Supercritical CO2- Proline Hydroxylase Case Western Reserve University BMP2-derived Pancreatic Substitute Treated Human Domain 2 Silencing Peptide Aggregation Based on Genetically Amniotic Membrane Enhances Vascularization Melissa A. Kinney Conjugated to Engineered Intestinal and Adipose Derived of Tissue Scaffolds In Wallace H. Coulter, Department of Biomedical Engineering - Todd McDevitt Laboratory Amphiphilic PEG Endocrine Cells Stem Cells based Vivo Georgia Institute of Technology and Emory University Macromers in Epithelial Autograft for 9:30 AM Coffee Break - Terrace Foyer Aqueous Solution Wound Regeneration Meeting Centennial III Centennial IV Regency V Regency VI Regency VII Room Meeting Centennial I Centennial II Centennial III Centennial IV Room Session I: Imaging Systemic Acellular Matrix Tumor Biology: Translational 10:00 - Technologies Regenerative Technologies Lessons Learned Approaches of Stem 2:00 - Ipsita Banerjee Dong Wang Jeong Hun Park Tatsuya Osaki 11:30 AM Effects Cells and Regenerative 2:15 PM University of University of California, POSTECH University of Tsukuba Medicine Pittsburgh Davis Technologies Translational Systems Analysis of Sox10+ Adult Stem Indirect Rapid Rapid Assembly of Approaches Translational Signal Transduction Cells Contribute to Prototyping of a Perfusable Microvascular- with Pluripotent Stem Pathway governing Wound Healing and Tracheal Bellows Graft Like Structures by Cells Self-renewal of Tissue Regeneration and its Application Electrochemical Cell Session Craig Duvall Bruce Bunnell Steve Badylak Ravi Rahul Thakar Human Embryonic to Tracheal Transfer Chairs Stem Cells Reconstruction Bellamkonda Katja Schenke- Manu Platt Brenda Ogle Dietmar Kevin Whittlesey 2:15 - Roger Kamm Kim O’Connor Tarun Saxena Georgia Papavasiliou Layland Hutmacher 2:30 PM Massachusetts Tulane University Georgia Institute of Illinois Institute of Student Shreya Raghavan Jenny Robinson Henk Hoogenkamp Amit Aurora Institute of Technology & Emory Technology Co-Chair Technology School of Medicine 10:00 - Kristin Poole Cherie Stabler Michael Zimber Lonnie Shea Rahul Thakar Kevin 10:15 AM Whittlesey Modeling Force Isolation of a Spatiotemporal Evaluation of Sensitivity Sensing through Subpopulation of Assessment of the and Specificity of Vanderbilt University of Histogen, Inc. Northwestern California Institute for Modulation of Mesenchymal Stem Blood-Spinal Cord MMP Substrates in University Miami University Regenerative Medicine Cytoskeletal Cells with Enhanced Barrier Permeability to PEG Hydrogels for Intravital Long-term Human Multipotent Engineering a Translational Tension Survival Based on Nanocarriers Neovascularization Optical Imaging Survival of Islets Stem Cell Proteins Pre-Metastatic Landscape and the Expression of Neuron- to Evaluate Encapsulated Support Soft Tissue Niche as a California Institute Glial Antigen 2 Peripheral in Ultrathin Regeneration Sensor for for Regenerative Arterial Disease Coatings Early Cancer Medicine 2:30 - Exhibit Viewing/Reception - Poster Session II Regency Ballroom Therapies within a Fully Detection 4:00 PM Mismatched 4:00 - TERMIS-Americas Thematic Working Interest Groups (TWIGs) Meetings – The Learning Center Allograft Murine 5:00 PM Model 10:15 - 7:00 PM Evening Special Event - at World of Coca-Cola – 121 Baker Street NW, Atlanta Anthony Molly Ogle Zegbeh Jallah Manu Platt Jane Lebkowski 10:30 AM Awojoodu Georgia Institute Georgia Institute University of Pittsburgh Georgia Institute Regenerative Patch of Technology of Technology of Technology Technologies In Vivo Hypoxia Tuning Investigating the The Direct Engineered Embryonic Detection with Monocyte Potential of Urinary Osteolytic Stem Cell Derived a Nanofiber Recruitment Bladder Matrix (Acell®) Potential of Implant to Treat Scaffold and Phenotype to Obviate Vaginal MCF-7 and Retinal Disease through Smooth Muscle and MDA-MB-231 Sphingosine- Nerve Degeneration Breast Cancer 1-Phosphate Following Implantation Cells in an In Receptors with Polypropylene Vitro Bone Mesh Environment

18 19 DAY 4 - WEDNESDAY, NOVEMBER 13, 2013 DAY 4 - WEDNESDAY, NOVEMBER 13, 2013

11:30 AM Lunch Break Meeting Centennial III Centennial IV Regency V Regency VI Regency VII Meeting Centennial III Centennial IV Regency V Regency VI Regency VII Room Room Session 2: Manufacturing Immuno- Remodeling & Pre-clinical Animal Early Translation of 10:30 - Laura Ricles Sittadjody Tanushree Thote Eliza Fong Jane Lebkowski 1:00-2:30 Platform modulation Repopulation of Models Tissue Engineered 10:45 AM Sivanandane Technologies Acellular Matrices Combinations The University of Wake Forest Georgia Institute of Rice University Continued Products Texas at Austin University School of Technology Session John Fisher Dolores Baksh Karen Christman Jennifer Elisseeff Rahul Thakar Medicine Chairs Gold Nanoparticle Restoring Bone Micronized Amnion Developing Engineered Masahiro Kino-oka Ned Waller Shay Soker Wan-Ju Li Kevin Whittlesey Monitoring of Metabolism in an ECM as a Tissue a Clinically Embryonic Stem Student Zohreh Izadifar Adam Young Abritee Dhal Mahsa Mohiti Mesenchymal Ovarian Failure Engineering Based Relevant In Cell Derived Co-Chair Stem Cells for In Model Using a Intervention for OA Vitro Model of Implant to Treat 1:00 - Masahiro Kino-oka Edmund Waller Stephen Badylak Dietmar Hutmacher Alfred Lane Vivo Applications Tissue Construct- Bone Metastatic Retinal Disease 1:15 PM Osaka University Emory University University of Queensland Stanford University Related to Ischemic Based Hormone Prostate Cancer Pittsburgh University of Repair Replacement Technology Therapy Automation Enhancing A Biologic Delayed Cell Cell-based Therapy 10:45 - Xinping Zhang Samer Zaky Adam Young Seema Ehsan System for Cell Adaptive Anti- Scaffold Approach Injection of for a Lethal Genetic 11:00 AM University of Center for University of California, University of Processing Based Tumor Immune to Promote Allogenic Skin Disease Rochester Medical Craniofacial San Diego California, Irvine on the Flexible Responses by Functional Mesenchymal Center Regeneration Modular Platform Modulating VIP Skeletal Muscle Progenitor Cells for Intravital Imaging Osteo Injectable Adipose A Three- Signaling in Patients with Bone Regeneration of Osteogenesis Conductivity of a ECM Hydrogels Dimensional in Volumetric in an Ovine Critical- and Angiogenesis Load- transducing Stimulate Vitro Model of Muscle Loss Sized Segmental in Repair and Elastomer is Neovascularization Vascularized Tibial Bone Defect Regeneration Enhanced and Subsequent Human Tumor 1:15 - Akon Higuchi Jaime Giraldo Vahid Serpooshan Salim Darwiche by Recruited Adipose Regeneration Tissue 1:30 PM National Central Stanford School of Ecole Polytechnique Periosteal Rather University Medicine Federale de Lausanne than Loaded The Isolation and Combination Engineered Autologous Osteoprogenitors Differentiation of of Cell Surface Epicardium Matrix Induced 11:00 - Eva Brauchle Maria Coronel Adam Taylor Chien-Chi Lin Steven Stice Human Adipose- PEGylation and Activates Cardiac Chondrogenesis 11:15 AM Fraunhofer IGB University of Miami University of Indiana University- University of Derived Stem Short-Course Regeneration Combined with Nottingham Purdue University Georgia Cells Using Immunotherapy Epiphyseal Chondro- Indianapolis Membrane for Prolonged Progenitor Cells Raman Downregulation Decellularized Synergistic Effect Using Filtration Method Survival of for the Treatment Spectroscopy on of Hypoxia Matrices from a of Extracellular Differentiated Pancreatic Islets of Full Thickness the Cardiovascular Induced Apoptotic Pro-Inflammatory Cues on Growth Cell Types from in an Allogeneic Cartilage Injuries Commitment and Pathways in Environment: Surface Inhibition Pluripotent Murine Model - an Experimental Cardiac Phenotypes Pancreatic Islets Analysis and Cell of Human Stem Cells to GLP-grade Safety of Mouse via Oxygen Response Pancreatic Model Normal Study in Goats Embryonic Stem Generating Ductal and Diseased 1:30 - Shashi Murthy Sangeetha Elizabeth Calle Young Min Ju Sophie Deng Cells Differentiated Adenocarcinoma Tissues for Drug 1:45 PM Srinivasan toward the Cells in 3D Development Northeastern Georgia Institute of Yale University Wake Forest School of University of Cardiovascular Fate University Technology Medicine California, Los 11:15 - Lizhi Cao Bruce Bunnell Sean Murphy Susan Thomas Angeles 11:30 AM Georgia Institute of Tulane University Wake Forest University Georgia Institute of Microfluidic Biomaterial-Based Regenerative In Vivo Evaluation Engineering Technology Technology Isolation of Engineering of Capacity of of Electrospun Replacement A Conformation Adult Stem Cells Amnion Hydrogel Building Epidermal Skin Dendritic Cell Distal Epithelium Bilayered Vascular Cornea from Specific from Adipose Accelerates Skin a Cancer Stem Cells Environments Cultivated in a Scaffold for Autologous Stem Antibody Against Tissue and Wound Healing Nanotherapeutic Enables Hair for Tolerance Decellularized Engineering Small Cells Fibronectin: Bone Marrow Exploiting Growth in Nude Induction Lung Extracellular Diameter Blood Applications for Ameliorate the Tumor Immuno Mice Matrix Scaffold Vessels Imaging of the Symptoms of Pathophysiology Ecm for Tissue Experimental Engineering Autoimmune Encephalomyelitis 20 21 DAY 4 - WEDNESDAY, NOVEMBER 13, 2013 DAY 4 - WEDNESDAY, NOVEMBER 13, 2013

Meeting Centennial III Centennial IV Regency V Regency VI Regency VII Meeting Centennial III Centennial IV Regency V Regency VI Regency VII Room Room 1:45 - Hyun-Wook Kang Gustavo Garlet James Williams Mon Tzu Li Sophie Deng 3:00 - Rameshwar Rao Ranieri Cancedda Paul Wolpe Benjamin Corona Scott Burger 2:00 PM Wake Forest Faculdade de Wake Forest Health Georgia Institute Continued 3:15 PM University of University of Genova Emory United States Army Advanced School of Medicine Odontología Sciences of Technology & Michigan University Institute of Surgical Cell and Gene de Bauru - Emory University Research Therapy Universidade de Dual-Phase Mesenchymal Stem Cells From Live Impaired Regulatory and São Paulo Osteogenic and (MSC) Induce the Homing Donor to Live Musculoskeletal Manufacturing 3-D Bioprinting Therapeutic Arrest Antibody-Directed Novel Volumetric Engineering Vasculogenic of Endogenous Progenitor Recipient: The Healing in a Rat Considerations of Innervated of Experimental Cellularization of Muscle Loss Replacement Engineered Tissue Cells through the Ethics of Tissue Composite Injury for Skeletal Muscle Periodontitis Heart Valve Implants Model in the Rat Cornea from for Bone Formation Activation of Alternatively Research as a Model Regenerative Tissue for Progression Biceps Femoris Autologous Stem Activated Macrophages in Therapeutic Medicine Accelerated by CCL22 is for Screening of Cells an Ectopic Bone Formation Bridge Products Restoration of Mediated by a ECM-Derived Model Muscle Function CCR4-Dependent Scaffolds 3:15 - In Kap Ko Scott Burks Regulatory T Cells 3:30 PM Wake Forest School National Institutes of Health Chemoattraction of Medicine Clinical Center 2:00 - Yuan Pang Tracy Ooi Bryan Brown Franklin West Scott Burger, Alfred CD31 Antibody Noninvasive Targeting 2:15 PM University of Tokyo University of Texas University of Pittsburgh University of Lane, Sophie Deng Conjugation of Mesenchymal Stem at Austin Georgia Improves Re- Cells (MSC) to Kidneys Engineering an Generating Reconstruction of Pre-Clinical Panel Discussion endothelialization by Clinically-Relevant Implantable Antigen-Specific T the TMJ Disc Using Middle Cerebral – Laying a Strong of Acellular Kidney Pulsed Focused Ultrasound Liver Construct Cells from Mouse an ECM Device in Artery Occlusion Foundation for Scaffolds for Whole Enhances Both Protective based on and Human a Porcine Model of Ischemic Stroke Translation of Organ Engineering and Regenerative Perfusion Culture Stem Cells: a Meniscectomy Pig Model Regenerative Capabilities of MSC of Cellular Bioengineering Medicine in a Murine Model of Aggregates in Approach Research Cisplatinum-Induced Acute Scalable Three- Kidney Injury dimensional 3:30 - Laura Struzyna Joel Wise Jason Robert Nick Willett Karen Christman Scaffold 3:45 PM University of University of Michigan Arizona State Georgia Institute of UCSD 2:15 - Katsuhisa Matsuura Cynthia Giver Robert Tranquillo Alexander Bailey Pennsylvania Technology 2:30 PM Tokyo Woken’s Emory University, University of Minnesota Food and Drug Tissue Engineered Delivery of a Combination From Bench Composite Bone Injectable Medical University Winship Cancer Administration Grafts Accelerate of Fresh Marrow Cells and to Clinic: and Muscle Extracellular Institute Peripheral Nerve Purified Mesenchymal Challenges and Injury Attenuates Matrix-Derived The Use of Donor In Vivo Remodeling Evaluation of Repair by Direct Stem Cells within Collagen- Opportunities Revascularization Hydrogel Developments Plasmacytoid of Decellularized, Tumorigenicity Axon-Induced Axon Chitosan Microbeads of a Segmental for Treating of Three- Dendritic Cells to Completely-Biological for Cell-based Regeneration Enhances Ectopic Bone Bone Defect Myocardial Dimensional Optimize Donor Tissue-Engineered Regenerative Formation Infarction Suspension T-cell Activity Arterial Grafts Medicine 3:45 - Youssef Farhat Warren Gray Aaron Levine Daniel Hickey Culture System in Allogeneic Products: a 4:00 PM University of Georgia Institute of Georgia Institute Northeastern for Human iPS Stem Cell Retrospective Rochester Technology/Emory University of Technology University Cells Expansion Transplantation Review of TGF-β1 Decreases Cardiac Progenitor Cells Regenerative Magnesium Oxide and Cardiac CBER/OCTGT Plasmin-Mediated Release microRNA-Loaded Medicine and Nanoparticles Differentiation Experience 2006- MMP Activity in Exosomes that Enhance the Challenge Increase 2011 Flexor Tendon Angiogenesis and Mitigate of Unproven Osteoblast 2:30 PM Break Cells: Implications Hypoxic Death Stem Cell and Fibroblast Session 3: Rejuvenation of Paracrine Factor Public Policy Polytrauma Pathway to for Scarless Tendon “Therapies” Functions on 3:00-4:30 Tissue & Organ Effects Models the Clinic with Repair Poly(l-lactic Function Regenerative Acid) Composites Medicine Products for Tendon to Session Robert Christy Eben Alsberg Aaron Levine David Baer Rahul Thakar Bone Insertion Chairs Applications Marsha Rolle Kacey Marra Mark Hamrick Kevin Whittlesey Student Sarah Griffiths CW Jenny Chang Jinah Jang Etai Sapoznik Co-Chair 22 23 DAY 4 - WEDNESDAY, NOVEMBER 13, 2013 POSTER SESSION I – MONDAY, NOVEMBER 11, 2013 4:30 – 6:00 PM

Meeting DRUG DELIVERY PRINCIPLES 106 111 ENGINEERING OF MATRIX Centennial III Centennial IV Regency V Regency VI Regency VII Michael To James Dennis COMPOSITION Room 100 Precisely Investigating Physical Changes of Tissue Engineering of an Epithelialized 4:00 - Riccardo Gottardi PLGA Microspheres during Drug Release Scaffold-free Neotrachea 117 Olive Mwizerwa Matthew Skiles Albert Cheng Dolores Baksh Autologous Stem Cell Recruitment for Process using Monodisperse Microspheres Tanya K. Meyer (2); Kristina G. Bernardi Jean-Michel Bourget 4:15 PM Massachusetts University of South Carolina Georgia Institute of Organogenesis Articular Cartilage Regeneration Jun Wu (1), Kelvin W.K. Yeung (2), Anderson (2);Thomas J. Kean (2); James E. Dennis (2) Development of a Microstructured Scaffold Riccardo Gottardi (1); Mintai Peter Hwang Shum (3), Michael K.T. To (4) Otolaryngology, University of Washington, Made from Fibroblast-Derived ECM to General Hospital Technology (2); Matthew Simson (3); Paul A. Manner (4); Department of Orthopaedics and Seattle, WA (1); Hope Heart and Matrix Produce a Tissue-Engineered Vascular Media Engineered Tuning Local Hypoxia to Discussion The Effect of Lessons from Jian Tan (5); Peter G. Alexander (6); Steven R. Traumatology, Li Ka Shing Faculty of Biology Program, Benaroya Research Institute Jean-Michel Bourget (1,2); Véronique Skeletal Muscle for Impact Secretion of VEGF with All Concomitant Hind a Successful Little (7); Rocky S. Tuan (8) Medicine, The University of Hong Kong; at Virginia Mason, Seattle, Washington (2) Laterreur (1,3); Maxime Guillemette(1,2,4); Department of Orthopaedic Surgery, School Department of Mechanical Engineering, Robert Gauvin (1,5); Caroline Miville-Godin Craniomaxillofacial from ASC Spheroids the Above Limb Ischemia FDA Review of Medicine, University of Pittsburgh (1); Faculty of Engineering, The University of 112 (6); Maxence Mounier (6); Jean Ruel (3); Reconstruction Speakers on Early Vascular Process for Ri.MED Foundation (2); Department of Hong Kong Chandrasekhar Kothapalli François A. Auger (1,2); Teodor Veres (6), Chemical and Petroleum Engineering, Spatio-temporal Diffusion of Biomolecular Lucie Germain (1,2) Growth and Gene an Allogeneic University of Pittsburgh (3); Department of 107 Gradients within 3D Scaffolds Regulate LOEX - Centre de recherche FRQS du Centre Expression in Cell Therapy Bioengineering, University of Pittsburgh (4); Anup Tuladhar Neurite Outgrowth and Turning hospitalier universitaire (CHU) de Québec, rhBMP-2-mediated Department of Mechanical Engineering and Local Delivery of Cyclosporine to the Brain Michael A. Sawonik, Chandrasekhar R. Canada (1); Département de Chirurgie, , University of Pittsburgh for Endogenous Stimulation Kothapalli Faculté de Médecine, Université Laval, Segmental Bone (5); Department of Immunology, University after Stroke Department of Chemical & Biomedical Québec, QC, Canada (2); Le bureau de Defect Repair of Pittsburgh (6); The McGowan Institute Institute of Biomaterials and Biomedical Engineering, Cleveland State University, design, Département de génie mécanique, for Regenerative Medicine, University of Engineering, University of Toronto, Toronto, Cleveland, Ohio Faculté des sciences et de génie, Université 4:15 - Hyun Ju Lim James Williams Marcello Pilia Pittsburgh (7); Department of Orthopedics Ontario, Canada (1); Department of Chemical Laval (3); Département de Physique, Faculté 4:30 PM and Sports Medicine, University of Engineering and Applied Chemistry, 113 des sciences et de génie, Université Laval and Wake Forest Wake Forest Health Sciences United States Army Washington (8) University of Toronto, Toronto, Ontario, Kellin Krick Biomedical Engineering Department, Quebec University Institute of Surgical Canada (2); Department of Surgery, University Neurotrophic Factor Gradient Presentation Heart and Lung Institute, Québec, Canada Research 101 of Toronto, Toronto, Ontario, Canada (4) for Migration Guidance of Human Schwann (4); Quebec Center for Functional Materials Esmaiel Jabbari Cells (CQMF), Université Laval, Canada (5); Life Donor Derived A Comparison of Cellular Transplantation Sequential Release of VEGF and BMP2 108 Kellin D. Krick (1); Yu-Ja Huang (2); Sciences Division, Biomedical Engineering, Skeletal Muscle and Acellular (Chemokine) of Microvascular Proteins in PEG-Based Hydrogel Jun Wu Russell Martin (2); Peter C. Searson (2); Ali McGill University, National Research Council Micropatterns Precisely Investigating Physical Changes of Khademhosseini (3); Ahmet Hoke (4); Hai- Canada, Boucherville, Canada (6) Precursor Cells Therapy in a Primate Fragments in an University of South Carolina, Columbia, PLGA Microspheres during Drug Release Quan Mao (2) Improve Muscle Model of Urinary Sphincter Experimental South Carolina Process using Monodisperse Microspheres Biomedical Engineering, Johns Hopkins 118 Functions in a Deficiency Volumetric Muscle Seyedsina Moeinzadeh, Danial Barati, Jun Wu; Kelvin WK Yeung; Michael KT To School of Medicine (1); Materials Science and Valérie Brun Esmaiel Jabbari Orthopaedics & Traumatology, LKS Faculty of Engineering, Johns Hopkins University (2); In Vitro and In Vivo Evaluation of Chitosan/ Murine Model Loss Model Medicine, The University of Hong Kong Health Sciences and Technology, Harvard- Hydroxyapatite Hybrid Matrices for of X-Linked 102 MIT (3); Neurology and Neuroscience, Johns Optimized Bone Regeneration Ronald Jiménez Cruz ENGINEERING MORPHOGENESIS Hopkins School of Medicine (4) Valérie Brun (1); Christine Guillaume (1); Myotubular Optimization of Collagen I Scaffolds by Richard Gouron (2); Romuald Mentaverri Myopathy Incorporating Microgels for Controlled 109 114 (2); Sylvie Bouthors(1); Dominique Laurent- 4:30 - Release of a Calendula Officinalis Extract Luis Alonzo Rutwik Rath Maquin (1); Sophie Gangloff (1); Halima Closing Ceremony - Centennial III Ronald Jiménez (1); Diana Millán (2); Edward A Dual-Chamber Microfluidic Device to Role of Cardiac Maturation in Cell Alignment Kerdjoudj (1); Frédéric Velard (1) 5:00 PM Suesca (3); Marta Fontanilla (4); Study the Effects of Interstitial Flow in Tumor as a Function of Matrix Fiber Spacing (1) EA 4691 BIOS, SFR Cap-Santé (FED4231), Tissue Engineering Group, Department of Angiogenesis Rutwik Rath (1); Douglas B. Sawyer (2); Hak- University of Reims Champagne-Ardenne SYIS-AM Poster Awards Presentations - Rebecca Dahlin, SYIS-AM Chair and Tracy Hookway, Pharmacy Luis Alonzo (1,2); Monica Moya (1,2); Marian Joon Sung (1,2); (2) INSERM UMR-S1088, SFR Cap-Santé SYIS-AM Vice-Chair Waterman (3,4); Chris Hughes (1,2,5); Steven Department of Biomedical Engineering, (FED4231), University Picardie Jules Verne 103 George (1,2,6) Vanderbilt University (1); Division of Makoto Komura Biomedical Engineering, University of Cardiovascular Medicine, Vanderbilt 119 Promotion of Tracheal Cartilage Growth California Irvine (1); Edwards Lifesciences University (2) Lisa Carey TERMIS-AM Membership Business Meeting (We invite everyone to attend!) - Chaired by: by Intra-tracheal Administration of Basic Center for Advanced Cardiovascular In vivo Degradation of Porcine Dermal Robert E. Guldberg, PhD, TERMIS-AM Chair Fibroblast Growth Factor (b-FGF) Technology (2); Microbiology and Molecular 115 Extracellular Matrix: A Quantitative Study Makoto Komura (1,2); Hiroko Komura (1); Genetics, University of California Irvine (3); Robert Schramm Lisa E. Carey (1); Christopher Dearth (2); Scott Kenichirou Konishi (1) Cancer Research Institute Research Centers Label-Free Electrochemical Detection of Johnson (3); Stephen F. Badylak (4) Department of Pediatrics Surgery, School of and Institutes, University of California, Irvine Salivary Gland Protein Products Enables McGowan Institute for Regenerative Medicine, Saitama Medical University (1); (4); Molecular Biology and Biochemistry, Rapid Characterization for In-Vitro Tissue Medicine, University of Pittsburgh (1); Department of Pediatric Surgery, Graduate University of California, Irvine (5); Chemical Engineering Department of Bioengineering, University School of Medicine, University of Tokyo (2) Engineering and Material Science, University Robert A. Schramm (1); David A. Soscia (1); of Pittsburgh (2); Department of Surgery, of California, Irvine (6) Kavitha Jayarathanam (1); Sharon J. Sequeira University of Pittsburgh (3) 104 (2); James Castracane (1); Melinda Larsen (2) Weiping Ren 110 College of Nanoscale Science and 120 Release of Doxycycline Loaded in Shruti Balaji Engineering (1), State University of New York; Chia-Wei Chang Polycaprolactone/Polyvinyl Alcohol Pdx1 And Epidermal Growth Factor Induce Biological Sciences, University at Albany (2) Characterization of Porcine SIS ECM Seeded Nanofibers for Implant Infection Wei Song Pancreatic Ductal Gene Expression In Human with Human MSCs for Cardiac Tissue (1); David C Markel (2,3); Weiping Ren (1,3) Amnion Epithelial Cells In Vitro 116 Engineering Department of Biomedical Engineering, Shruti Balaji (1,2); Yu Zhou (1); Anasuya Raymond Swetenburg Chia-Wei J Chang (1); Tye Petrie (2); Claus Wayne State University, Detroit, Michigan Ganguly (2); Emmanuel C Opara (1); Shay Towards a Model for Motor Neuron Sondergaard (2); Leigh G. Griffiths (1) (1); Detroit Medical Center & Providence Soker (1) Derivation from Pluripotent Stem Cells Veterinary Medicine & Epidemiology, Hospital Orthopaedic Residency, Detroit, Wake Forest Institute for Regenerative Raymond L. Swetenburg (1); Douglas E. University of California - Davis (1); Michigan (2); Department of Orthopaedic Medicine, Wake Forest Baptist Health (1); White (2,3); Erin T. Jordan (1); Melissa L. Department of Surgery, University of Surgery, Providence Hospital, Southfield, Department of Biological Sciences, Birla Kemp (2,3); Todd C. McDevitt (2,3); Steven California - Davis (2) Michigan (3) Institute of Technology & Sciences-Pilani, K.K. L. Stice (1) Birla Goa Campus (2) Regenerative Bioscience Center, The 121 105 University of Georgia, Athens, Georgia (1); Rebecca Dahlin Won Hyuk Suh The Wallace H. Coulter Department of Enhancing the Chondrogenic Phenotype of Nanostructured Biomaterials for Stem Cell Biomedical Engineering, Georgia Institute Articular Chondrocytes in Flow Perfusion Engineering of Technology & Emory University, Atlanta, Rebecca L. Dahlin; Ville V. Meretoja; Bioengineering Department, Temple Georgia (2); The Parker H. Petit Institute for Mengwei Ni; F. Kurtis Kasper; Antonios G. University Bioengineering and Bioscience, Georgia Mikos Institute of Technology, Atlanta, Georgia (3) Bioengineering, Rice University

24 25 POSTER SESSION I – MONDAY, NOVEMBER 11, 2013 4:30 – 6:00 PM POSTER SESSION I – MONDAY, NOVEMBER 11, 2013 4:30 – 6:00 PM

122 128 134 141 147 152 158 164 George Fercana Bryant Menn Patrick Thayer Petra Kerscher Stephanie Teeter Mona ElRefaey Kristin French Homeyra Pourmohammadali Bioactive Scaffolds for Peripheral Vascular Ultra-low Crosslinked Microgels Create Cylindrical Composite Scaffolds for Ligament Engineering Developing Human Heart Tissue PDLIM4 and Corin are Key Regulators Nutrient Activation of Distinct Signaling Cardiac Progenitor Cells are Sensitive to Significant Effect of Hydromechanical Surgery Bimodal Pore Sizes in Fibrin Extracellular Tissue Engineering for Investigating Mechanisms of Congenital of hMSC Osteogenesis and Terminal Pathways in Bone Marrow Mesenchymal Stem Tensile Strain and Matrix Composition vs Mechanical Stimulation on Collagen George R. Fercana (1); Devon A. Bowser Matrices - Implications in Tissue Engineering Patrick S. Thayer (1); Aaron S. Goldstein (1,2) Heart Defect Formation Differentiation in Hypoxic Conditions Cells is Dependent on Oxygen Pressure Kristin M. French (1); Marcos J. Fierro (1); Production of a Chondrocyte-seeded Hydrogel (1); Eugene M. Langan III (2); Christopher G. Bryant Y. Menn (1); Alison M. Douglas (1); L. School of Biomedical Engineering and Petra Kerscher (1); Irene C. Turnbull (2); Stephanie Teeter (1); Adisri Charoenpanich (1); Mona ElRefaey (1,2); Qing Zhong (1,2,3); Todd D. Johnson (2); Karen L. Christman (2); Homeyra Pourmohammadali (1); Naveen Carsten III (2); Dan T. Simionescu (1) Andrew Lyon (2,3); Thomas H. Barker (1,3) Sciences, Virginia Polytechnic Institute and Blakely S. Bussie (1); Dror Seliktar (3); Kevin Elizabeth Loboa (1) Xingming Shi (1,2,4); William Hill (1,2,4); Yun Michael E. Davis (2) Chandrashekar (2); John B. Medley Bioengineering, Clemson University (1); Biomedical Engineering, Georgia Institute of State University (1); Department of Chemical D. Costa (2); Elizabeth A. Lipke (1) Joint Department of Biomedical Engineering, Su (2) Lakiea Bailey (1,2); Norman Chutkan Biomedical Engineering, Emory University (1); Waterloo Tissue Engineering Mechanics Lab, Department of Surgery, Greenville Health Technology (1); Chemistry and Biochemistry, Engineering, Virginia Polytechnic Institute and Chemical Engineering, Auburn University, State University and University (6) Ke-Hong Ding (1,2,3); Wendy Bollag (2,7); Bioengineering, University of California San Department of Mechanical and Mechatronics System (2) Georgia Institute of Technology (2); State University (2) Auburn, Alabama (1); Department of of North Carolina at Chapel Hill (1) Mark Hamrick (2,5,6); Carlos Isales (1,2,6); Diego (2) Engineering, University of Waterloo (1); Bioengineering and Biosciences, Georgia Cardiology, Icahn School of Medicine at Institute of Molecular Medicine and Genetics, Waterloo Tissue Engineering Mechanics Lab, 123 Institute of Technology (3) 135 Mount Sinai, New York (2); Department of 148 Georgia Regents University (1); Institute 159 Department of Mechanical and Mechatronics Kimberly Ferlin Prasad Vaidya Bioengineering, Technion-Israel Institute of Brian Wile for Regenerative and Reparative Medicine, Fiona Griffin Engineering, University of Waterloo (2); Protein-Modified PEGDA Hydrogels Increase 129 FITC-BSA Loaded Chitosan/PLL Alginate Technology, Technion City, Haifa, Israel (3) Molecular Beacons as a Tool to Separate Georgia Regents University (2); Department Adhesion Junctions Regulate the Cytoskeletal Waterloo Tissue Engineering Mechanics Lab, Mesenchymal Stem Cell Adhesion and Anja Metzner Microspheres in Electrospun Scaffold Cardiomyocytes from Differentiating of Medicine (3); Department of Pathology, Response to Fluid Flow Stimulus Department of Mechanical and Mechatronics Spreading Comparison of Two Different Prasad Vaidya (1); Aaron Goldstein (2) 142 Pluripotent Stem Cells Georgia Regents University (4); Department Fiona E. Griffin (1); Muriel C. Voisin (1); Engineering, University of Waterloo (3) Kimberly M. Ferlin (1); David S. Kaplan (2); Decellularization Methods for Tissue Chemical Engineering Department, Virginia Mahsa Mohiti-Asli Brian Wile (1); Kiwon Ban (2); Sangsung Kim of Cellular Biology and Anatomy, Georgia Matthew G. Haugh (1); Peter Owens (2); John P. Fisher (1) Engineering of Pulmonary Heart Valves Polytechnic Institute and State University Skin Tissue Engineering for the Infected (2); Jaemin Byun (2); Talib Saafir (3); Mary Regents University (5); Department of Patrick J. McGarry (1); Laoise M. McNamara 165 Fischell Department of Bioengineering, Jessica Boldt; Georg Lutter; Huangdong Dai, Wound Site: Evaluations of PLA Nanofibers Wagner (3); Young-sup Yoon (2); Gang Bao (1) Orthopaedic Surgery, Georgia Regents (1) Yi-Xian Qin University of Maryland - College Park (1); Martin Marczynski-Buehlow, Beke Sarrahs, and Novel Approach for Silver Ion Release Biomedical Engineering, Georgia Institute University (6); Department of Physiology, Biomechanics Research Centre (BMEC), Guided Noninvasive Acoustic Radiation Force Center for Devices and Radiological Health, Jan Schoettler; Jochen Cremer; Anja Metzner ENGINEERING TISSUES FOR IN VITRO in a Co-Culture System of Keratinocytes and of Technology and Emory University (1); Georgia Regents University (7) National University of Ireland, Galway, Ireland for Promoting Bone Fracture Healing and Food and Drug Administration (2) Department of Cardiovascular Surgery, SCREENING & DIAGNOSTICS Staphylococcus Aureus Cardiology, Emory University (2); Pediatrics, (1); Centre for Microscopy and Imaging, Regeneration Christian-Albrechts-University of Kiel, School Mahsa Mohiti-Asli (1); Behnam Pourdeyhimi Emory University (3) 153 National University of Ireland, Galway, Ireland Yi-Xian Qin (1); Long Bi (2); Maria Pritz (3) 124 of Medicine, Kiel, Germany 136 (1); Elizabeth G. Loboa (2) Laura Marquardt (2) Biomedical Engineering, Stony Brook Paulomi Ghosh Pedro Baptista College of Textiles, North Carolina State 149 Effect of GDNF on Schwann Cell Phenotypes University In vitro and In Vivo Biocompatibility of 130 Recapitulation of Human Liver Embryonic University (1); Joint Department of Biomedical Ling Wu and Role in Neurite Outgrowth 160 Ionically Crosslinked Chitosan Micro/Nano Harsh Patel Development on Decellularized Liver Matrix Engineering, University of North Carolina Functional Cell Sorting Based on Extracellular Laura M. Marquardt (1); Shelly E. Sakiyama- Sarah Griffiths 166 Fibers for Tissue Engineering Applications Comprehensive Study of Three Different PCL: Pedro M. Baptista (1); Dipen Vyas (1); Emma at Chapel Hill and North Carolina State Matrix Domain Detection (EMDD) Elbert (1) Endothelial Associated Shear Sensitive Genes Xin Qu Paulomi Ghosh; Arunprabhu Rameshbabu; PGC Tubular Scaffolds for Potential Vascular Moran (1); Anthony Atala (1); Shay Soker (1) University (2) Ling Wu (1); Frank A. Petrigliano (1); David R. Biomedical Engineering, Washington and Epigenetic Profiles in Mesenchymal Stem Relative Impact of Uniaxial Alignment vs. Santanu Dhara Graft Application Wake Forest Institute of Regenerative McAllister (1); John S. Adams (1,2,3); Paul D. University in St. Louis (1) Cells Form-Induced Stress on Differentiation of School of Medical Science and Technology, Harsh N Patel (1); Vinoy Thomas (2); Yogesh Medicine, Wake Forest University Health 143 Benya (1); Denis Evseenko (1,2,3) Sarah Griffiths (1); Yunzhe Zhang (1); Yuhong Adipose Derived Stem Cells Indian Institute of Technology, Kharagpur K Vohra (3) Sciences, Winston-Salem, North Carolina(1) Emma Moran Orthopaedic Surgery, Orthopedic Hospital 154 Fan (1); Robert Nerem (1) Xin Qu (1), Wei Zhu (1); Samuel Huang (2); Biomedical Engineering, University of Bioengineered Liver Organoids as a Novel Research Center, David Geffen School Eun Jin Son Institute of Bioengineering and Bioscience, Julie Yi-Shuan Li (2); Shu Chien (2); Shaochen 125 Alabama at Birmingham (1); Materials 137 Platform to Model Fluid Biomechanics, of Medicine, University of California at Gene Expression Patterns during Development Georgia Institute of Technology (1) Chen (1) Erik Hadley Science and Engineering, University of Mariea Brady Regulation of Liver Development and Los Angeles (1); University of California, of Cochlear Tonotopy Department of NanoEngineering, University Completely Defined Pluripotent Stem Cell Alabama at Birmingham (2); Department of Integration of an Automated Perfusion Regeneration Los Angeles, Broad Stem Cell Institute Eun Jin Son (1) 161 of California, San Diego (1); Department of Culture Using mTeSR™1 and TeSR™-E8™ Physics, University of Alabama at System into a High-throughput Magneto- Emma C. Moran (1,2); Pedro M. Baptista (2); for Regenerative Medicine and Stem Cell Department of Otorhinolaryngology, Yonsei Greg Harris Bioengineering, University of California, San Maintenance Media with Vitronectin XF™ Birmingham (3) Mechanostimulation Device for Cartilage Jessica L. Sparks (3); Shay Soker (1,2) Research (2); University of California, Los University College of Medicine, Gangnam Discriminating the Influence of Cell Shape Diego (2) Erik B. Hadley (1); Mandy Chan (1); Rachel Tissue Engineering Virginia Tech-Wake Forest School of Angeles, Jonsson Comprehensive Cancer Severance Hospital (1) and Matrix Elasticity on Mesenchymal Stem Liu (1); Jessica Norberg (1); Allen C. Eaves 131 Mariea A Brady (1); Xiaoming Shi (1); Reva Biomedical Engineering and Science, Center (3) Cell Lineage Commitment 167 (1,2); Terry E. Thomas (1); Sharon A. Louis (1) Satyavrata Samavedi Vaze (1); Harsh D. Amin (1); Darryl R. Overby Wake Forest University (1); Wake Forest MECHANOTRANSDUCTION Greg M. Harris; Ehsan Jabbarzadeh Bill Tawil STEMCELL Technologies Incorporated, An Electrospun Mesh Possessing Region- (1); C. Ross Ethier (1, 2) Institute for Regenerative Medicine, Wake 150 Chemical Engineering, University of South Impact of Fibroblast Growth Factor on Vancouver, British Columbia, Canada (1); wise Differences in Fiber Alignment for the Department of Bioengineering, Imperial Forest University (2); Chemical and Paper Bin Yang 155 Carolina Mesenchymal Stem Cell Osteogenic Terry Fox Laboratory, British Columbia Cancer Potential Regeneration of Bone-Ligament College London, South Kensington, London, Engineering, Miami University (3) Paracine Trophic Effect and Cell Differentiation Dekel Dado-Rosenfeld Differentiation and Migration Agency, Vancouver, British Columbia, Canada Transitions United Kingdom (1); Wallace H. Coulter of Human Urine-Derived Stem Cells External Forces Applied on Embryonic Stem 162 Armaun Emami (2); Jesus Fajardo (2); Mai (2) Satyavrata Samavedi (1); Prudhvidhar Department of Biomedical Engineering, 144 Seeded on 3D Porous Scaffold for Potential Cells in 3D Can Direct Early Differentiation Esmaiel Jabbari Nguyen (2); Takahiro Watanabe (2); Elaheh Gaddam (1); Abby R Whittington (1,2,3); Georgia Institute of Technology, Atlanta (2) Bao-Ngoc Nguyen Application in Ureter Tissue Regeneration Toward a Specific Germ Layer Effect of Matrix Compressive Modulus on Asghari (2); Surbhi Dutta (2); Arthela Osorio 126 Aaron S Goldstein (1,3) Effect of Culturing Location of Human Bin Yang; Guihua Liu; Rongpei Wu; Lujie Dekel Dado-Eosenfeld (1); Shulamit Zonal Marker Expression of Stromal Cells in (2); Tom Velasco (2); Melissa McCoy (2); Bill Henk Hoogenkamp Chemical Engineering, Virginia Polytechnic 138 Mesenchymal Stem Cells in Tubular Song; Anthony Atala; Yuanyuan Zhang Levenberg (1) Chondrogenesis Tawil (1) Induction of Shape Memory in Collagen Institute and State University (1); Materials Rachel Campbell Perfusion System Bioreactor on Osteogenic Wake Forest Institute for Regenerative Biomedical Engineering Department, Technion Ozan Karaman (1); Sinan Guven (2); Ryan Department of Bioengineering, University of Scaffolds by Chemical Crosslinking under Science and Engineering, Virginia Polytechnic Fabrication of Surgically Perfusable Differentiation Medicine, Wake Forest School of Medicine, Israel Institute of Technology, Israel (1) Porter (3); Christopher H. Evans (3); Utkan California, Los Angeles (1); Department of Physical Restrainment Institute and State University (2); School Microchannel-Containing Tissue-Engineered Bao-Ngoc B. Nguyen (1); Henry Ko (1); John Winston-Salem, North Carolina Demirci (2); Esmaiel Jabbari (1) Biotechnology & Bioinformatics, California Henk Hoogenkamp (1); Luuk Versteegden (1); of Biomedical Engineering and Sciences, Scaffolds P. Fisher (1) 156 University of South Carolina, Columbia, State University, Channel Islands (2) Dorien Tiemessen (2); Egbert Oosterwijk (2); Virginia Polytechnic Institute and State Rachel Campbell (1); Karina A. Hernandez Fischell Department of Bioengineering, INTERFACING REGEN MED WITH Christopher Dearth South Carolina (1); Brigham and Women’s Willeke F. Daamen (1); Toin H. van Kuppevelt University (3) (1); Tatiana Boyko (1); Jeremiah Joyce (1); University of Maryland - College Park (1) ‘OMICS Mechanical Loading/Rehabilitation as Hospital, Boston, Massachusetts (2); Beth REGENERATION-INDUCING (1) Kadria N. Derrick (1); Adam M. Jacoby (1); a Determinant Factor in Constructive Israel Deaconess Medical Center, Boston, BIOMATERIALS Department of Biochemistry, Radboud 132 Jason A. Spector (1) 145 151 Remodeling of Biologic Scaffolds Massachusetts (3) University Medical Centre (1); Department Sumona Sarkar Plastic Surgery, Weill Cornell Medical College Three-Dimensional Organoid Systems for Bryan Baker Christopher Dearth (1,2); Christian Ranallo (1); 168 of Urology, Radboud University Medical Synergistic Effects of Scaffold Structure and (1) Modeling Colon Carcinoma Metastasis and The Effects of Scaffold Morphology on Gene Michael Kochis (1); Brian Sicari (1); Edward 163 Rakhi A. Centre (2) Chemistry on Human Bone Marrow Stromal Anti-Cancer Drug Development Expression Profiles of Primary Human Bone Garay (1,3); Stephen Badylak (1,2,4) Sebastien Meghezi A Novel Three Dimensional Nanofibrous Cell Response to Fibrous Scaffolds 139 Aleksander Skardal Marrow Stromal Cells McGowan Institute for Regenerative Medicine, Static Maturation Allows Smooth Muscle Cells Scaffold for Differentiation of Stem Cells into 127 Sumona Sarkar (1); Bryan A. Baker (1); Carl G. Dean Chamberlain Aleksander Skardal (1); Mahesh Devarasetty Bryan A. Baker (1); P. Scott Pine (1); Girish University of Pittsburgh (1); Department to Effectively Remodel Collagen Gel Matrix Islet like Clusters Esmaiel Jabbari Simon Jr. (1); Joy Dunkers (1) A Modular Approach to the Development of (1); Shay Soker (1) Kumar(1,2); Kaushik Chatterjee (1,3); Jennifer of Surgery, University of Pittsburgh (2); Prior to Mechanical Stimulation in a Dynamic Rakhi A (1); Dhanesh V (1); Bindu P. Nair (1); Osteogenic Differentiation of Stromal Cells in Biosystems and Biomaterials Division, Liver Microtissues for In Vitro Drug Screening Wake Forest Institute for Regenerative H. McDaniel (1); Mark L. Salit (1); Carl G. Department of Physical Medicine & Bioreactor Prabha D. Nair (1) Cortical-Bone-Mimetic Microtubes National Institute of Standards and M. Dean Chamberlain (1,2); Michael V. Sefton Medicine, Wake Forest School of Medicine (1) Simon Jr. (1) Rehabilitation, University of Pittsburgh (3); Sebastien Meghezi (1); Dawit G Seifu (1); Division of Tissue Engineering and Ozan Karaman; Esmaiel Jabbari Technology (1) (1,2) Biosystems & Biomaterials Division, Department of Bioengineering, University of Diego Mantovani (1) Regeneration Technologies, Sree Chitra Tirunal University of South Carolina, Columbia, Institute for Biomaterials and Biomedical 146 National Institute of Standards and Pittsburgh (4) Laboratory for Biomaterials and Institute for Medical Sciences and Technology (1) South Carolina 133 Engineering, University of Toronto (1); Maria Stancescu Technology, Gaithersburg, Maryland (1); Bioengineering, Laval University, Québec City, Maria Soto Department of Chemical Engineering and In Vitro Platform for Pharmacological Cardiac Division of Biology, Office of Science and 157 Canada (1) 169 Isolation of Type II Collagen from Bovine Applied Chemistry, University of Toronto (2) Side Effects Testing Engineering Laboratories, Center for Devices Kyle Edmunds Nesreen Alsmadi Tracheal Cartilage and Production of Scaffolds Maria Stancescu (1); Peter Molnar (2,3); James and Radiological Health, Food & Drug Investigation of Cardiomyocyte Proliferation Axonal Regeneration Guided by Three using Two Different Methodologies 140 J. Hickman (1) Administration, Silver Spring, Maryland (2); on Fractionated Cardiac Extracellular Matrix Dimensional Gradient of Nerve Growth María E. Soto (1); Sergio A. Casadiegos (1); Kimberly Ferlin NanoScience Technology Center, University and Department of Materials Engineering, Derived from Perfusion-Decellularized Factors Edward B. Suesca (1); Marta R. Fontanilla (1) Characterization of Chondrocyte Adhesion on of Central Florida (1); Department of Zoology, Indian Institute of Science, Bangalore, India (3) Ventricular Tissue Nesreen Zoghoul Alsmadi (1); Parisa Lofti (1); Tissue Engineering Group, Laboratory 318, Fibronectin-Coated Substrates University of West Hungary (2); Biomedical Kyle J. Edmunds (1); Corin Williams (1); Joselito Razal (2); Gordon Wallace (2); Mario Department of Pharmacy,Universidad David S. Kaplan (1); Priyanka Durai (1); Engineering, Cornell University (3) Ngonidzashe Madungwe (1); Lauren D. Black I. Romero (1) Nacional de Colombia, Bogotá, Colombia (1) Kimberly M. Ferlin (2); John P. Fisher (2) III (1,2) Department of Bioengineering, University Center for Devices and Radiological Health, Biomedical Engineering, Tufts University of Texas, Arlington; University of Texas Food and Drug Administration (1); Fischell (1); Biomedical Sciences, Sackler School of Southwestern Medical Center, Dallas Department of Bioengineering, University of Graduate Biomedical Sciences (2) (1); University of Wollongong Australia, Maryland - College Park (2) Wollongong, Australia (2) 26 27 POSTER SESSION I – MONDAY, NOVEMBER 11, 2013 4:30 – 6:00 PM POSTER SESSION I – MONDAY, NOVEMBER 11, 2013 4:30 – 6:00 PM

170 176 182 188 193 200 206 212 Sogol Baharlou Alice Cheng Kshama Doshi Flavia Goncalves Claire Jeong Eun Young Kim Jin Ho Lee Srinivas Madduri Controlling Electrospun Fiber Alignment The Effects of Combined Micro-/Nano- Gas Cluster Ion Beam Modified Collagen Use of Co-polymer of PLLA and Poly- Optimized Design of Hyaluronic Acid Collagen Type I Caoted Silk and PLGA Film Plasmid DNA-Loaded Injectable Bioactive Influence of Nerve Growth Factor Availability and Guidance Features on Autonomic Axonal and Deposition by Using a Programmable Roughness on Osteoblast Response (HA)-Poly(ethylene glycol) (PEG) Composite for Corneal Endothelial Cells Regeneration Bulking Agent for the Treatment of Urinary Leads to Rapid Differentiation and Tissue (isosorbide succinate) on the Development of Regeneration for Bladder Tissue Engineering Oscillating Auxiliary Electrode Alice Cheng (1,2); William B. Goodwin (3); Regeneration Electrospinning Scaffolds Hydrogels for Intervertebral Disc Tissue (1); Eun Young Kim (1); Sun A. Cho, (2); Chun- Incontinence Soo Jung Choi (1); Se Heang Oh (2); In Gul Srinivas Madduri (1); Rita Gobet (2); Tullio Sogol M. Baharlou; Jonathan A. Rolando A. Gittens (4); Zvi Schwartz (5); Kshama Doshi (1); Matthew Fullana (2); Gary Flavia Gonçalves (1); Ricardo Bentini (1); Ana Regeneration Ki Joo (1); Dongwon Lee (1); Gilson Khang Kim (3); So Young Chun (4); Ji Youl Lee (3); Jin Sulser (3); Daniel Eberli (3) Gerstenhaber; Yah-el Har-el; Peter I. Lelkes Claire G. Jeong (1); Zhenbin Niu (2); Robert (1); Kenneth H. Sandhage (3); Barbara D. Boyan Wnek (2); Joseph Khoury (1) Claudia O Carreira (2); Patricia M Kossugue Ho Lee (1) Institute of Pharmaceutical Sciences, ETH Bioengineering Department, Temple (1,5) Exogenesis Corporation (1); Department of (2); Erik Halcsik (2); Mari Cleide Sogaya (2); Mancino (1); Aubrey T. Francisco (1); Stephen Department of BIN Fusion Technology, Zurich, Switzerland (1); University Children’s L. Craig (2); Lori A. Setton (1) Department of Polymer-Nano Science & Department of Advanced Materials, University Biomedical Engineering, Georgia Institute Macromolecular Science and Engineering, Luiz H Catalani (1) Hannam University (1); Department of Hospital, Department of Pediatric Surgery, Biomedical Engineering & Orthopaedic Technology and Polymer BIN Research of Technology and Emory University (1); Case Western Reserve University (2) Departamento de Química Fundamental, Nanobiomedical Science (2), Dankook Zurich, Switzerland (2); University Hospital, 171 Biomedical Engineering, Peking University Instituto de Química da Universidade de Surgery, Duke University, Durham, North Center, Chonbuk National University (1); Department of Urology, Zurich, Switzerland Carolina (1); Chemistry, Duke University, University; Department of Urology, Seoul John Brekke (2); Materials Science and Engineering, 183 São Paulo (1); Departamento de Bioquímica, Department of Ophthalmology and Visual Saint Mary’s Hospital, Catholic University (3) Durham, North Carolina (2) Chondrogenic and Osteogenic Differentiation Georgia Institute of Technology (3); Edward Ebert Instituto de Química da Universidade de São Science, College of Medicine, The Catholic (3); Joint Institute for Regenerative Medicine, of hMSCs Within a Biomimetic, 3D Bioinstrumentation and Bioengineering, Human Hair Keratins Influence Proliferation Paulo (2) University of Korea (2) 213 Kyungpook National University (4) Atsushi Mahara Microenvironment Instituto de Investigaciones Científicas y and Migration of Schwann Cells 194 Young Min Ju 201 Development of Small-caliber Decellularized John H. Brekke (1); Beth Lindborg (2); Servicios de Alta Tecnología (4); Biomedical Kate Coniglione; Al Roth; Georges 189 207 Long-Bypass Graft Modified with Bioactive In Situ Regeneration of Muscle Tissue through Eun Young Kim Timothy D. O’Brien (3) Engineering, Virginia Commonwealth Guillaume; Ashley Jackson; James Johnson; Yah-el Har-el Sue Hyun Lee Peptides for Rapid Endotherialization Bioactive Regenerative Therapeutics, Inc. (1); University (5) Jacqueline Maddux; C. Edward Ebert, PhD Electrospun Protein Scaffolds Improve Host Cell Recruitment Porcine Collagen Powder : Contribute to Effects of In Situ Cross-linkable Gelatin Young Min Ju; James J. Yoo; Anthony Atala; Atsushi Mahara (1); Shota Somekawa (1,2); Stem Cell Institute, University of Minnesota Department of Chemistry and Biomedical Healing in a Pig Full Thickness Skin Excision Growth Behavior of Corneal Endothelial Cells Hydrogels on Mesenchymal Stem Cells Naoki Kobayashi (1,3); Yoshiaki Hirano (3); Sang Jin Lee (2); Comparative Medicine, Veterinary 177 Research Infrastructure Center, Winston Wound Model Eun Young Kim (1); Ji Eun Jang (1); l Jeong Eun Sue Hyun Lee (1); Young Wook Chun (1); Yoshiharu Kimura (2); Toshiya Fujisato (4), Population Medicine Department, Stem Cell Colin Cook Salem State University Yah-el Har-el (1); Ross Brodsky(1); Jonathan Wake Forest Institute for Regenerative Song (1); Soon Hee Kim (2); Byoung-Hyun Yunki Lee (2); Ki Dong Park (2); Hak-Joon Tetsuji Yamaoka (1) Institute, University of Minnesota (3) Hierarchical Surface Topographies for Cell- A. Gerstenhaber (1); Richard B. Huneke (2); Medicine, Wake Forest School of Medicine Min (2); Chun-Ki Joo (3); Dongwon Lee (1); Sung (1) Department of Biomedical Engineering, Surface Interaction Studies 184 Peter I. Lelkes(1) Gilson Khang (1) Biomedical Engineering, Vanderbilt University National Cerebral and Cardiovascular 195 172 Colin A .Cook (1); Eric Xie (1); Jason J. Martin Ehrbar Bioengineering, Temple University (1); Department of BIN Fusion Technology, (1); Molecular Science and Technology, Ajou Center Research Institute (1); Department of Jin Woo Jung Tatiana Bressel Benkoski (2); Warren L. Grayson (1) Cell-instructive Biomaterials to Promote Microbiology and Immunology, Drexel Department of Polymer-Nano Science & University (2) Biobased Materials Science, Kyoto Institute Development of gelatin/PCL Blend Scaffold of Technology (2); Faculty of Chemistry, Effect of Titanium Surface Modification by Biomedical Engineering, Johns Hopkins Bone Healing by Mesenchymal Progenitor University College of Medicine (2) Technology and Polymer BIN Research with Nasal Implant Shape for Augmentation 208 Materials and Bioengineering, Kansai Laser Beam on Proliferation and Osteoblastic University (1); Applied Physics Laboratory, Recruitment Center, Chonbuk National University (1); Cell Rhinoplasty Shirae Leslie University (3); Department of Biomedical Differentiation of Human Mesenchymal Stem Johns Hopkins University (2) Philipp S. Lienemann (1); Vincnet Milleret (1); 190 Therapy Center, Ajou University School of Jin Woo Jung (1); Hyung-Seok Lee (1); Jung Controlled Released of Cells from Alginate Engineering, Osaka Institute of Technology (4) Cells Anna-Sofia Kivelioe (1); Stephanie Metzger Samuel Herberg Medicine (2); Department of Ophthalmology Min Hong (1); Jeong Hun Park (1); Yeong-Jin Microbeads for Bone Regeneration Tatiana A. B. Bressel (1), Jana Dara F. de 178 (1); Ana Sala (1); Matthias P. Lütolf (2); Martin and Visual Science, College of Medicine, The Suboptimal Bone Morphogenetic Protein-2 / Choi (2); Jung Hee Shim (3); Woojune Hur Shirae K. Leslie (1); David J. Cohen (1); Janina 214 Queiroz (1); Susana Moreira (1); Jéssyca T. Elizabeth Cosgriff-Hernandez Catholic University of Korea (3) Ehrbar (1) Stromal Cell-Derived Factor-1β Co-Therapy (3); La Mee Choi (3); Tae Hyun Choi (3); Sedlacek (2); Eric Pinsker (3); Zvi Schwartz (1) Russell Martin da Fonseca (1); Edson A. Filho (2); Antônio Chronic Wound Dressings Based on The Effect of Fiber Diameter on Migration Department of Obstetrics, University Zurich, Induces Bone in Critical- Size Rat Calvarial Dong-Woo Cho (1) and Barbara D. Boyan (1) Carlos Guastaldi (2); Silvia R. Batistuzzo de 202 Rate of Primary Human Schwann Cells Collagen-mimetic Proteins Switzerland (1); Laboratory of Stem Cell Defects Department of Mechanical Engineering, Biomedical Engineering, Virginia Medeiros (1) Elizabeth Cosgriff-Hernandez (1); Brooke Bioengineering, Ecole Polytechnique Federale Samuel Herberg (1,3); Cristiano Susin (2,4,6); Toyin Knight Commonwealth University (1); Division of Russell Martin (1); YuJa Huang (1); Shawn Lim Pohang University of Science and Technology Bioresponse of a Cell/alginate Hydrogel (2); Kellin Krick (2); Alex Mullen (1); Peter Celular Biology and Genetics Department, Russell (2); Pauline Luong (1); Mary Beth de Lausanne, Switzerland (2) Manuel Pelaez (2); R. Nicole Howie (4); (1); Division of Integrative Biosciences and Orthopedics, Otto-von-Guericke University Universidade Federal do Rio Grande do Browning (1); Anne Hocking (3); Magnus Rubens Moreno de Freitas (2); Jaebum Lee Composite in Mammalian Kidney (2); Biomedical Engineering, Georgia Institute Searson (1); Ahmet Hoke (3); Hai-Quan Mao Biotechnology, Pohang University of Science Toyin Knight (1); Richard Payne (1); Elias (1,2) Norte, UFRN, Natal, Brazil (1); Chemical Hook (2) 185 (2,4); Maribeth H. Johnson (5); Mohammed and Technology (2); Department of Plastic of Technology (3) Rivera (1); Joydeep Basu (1); Neil Robbins (1); Materials Science & Engineering, Johns Institute, Universidade Estadual Paulista, Texas Agricultural & Mechanical University, Mindy Ezra E. Elsalanty (4,8); Mark W. Hamrick (3,6,7,8); and Reconstructive Surgery, Seoul National Hopkins University (1); Biomedical Darell McCoy (1); Craig Halberstadt (1,2); 209 UNESP, Araraquara, Brazil (2) College Station (1); University System Health Development of Transplantable Tissue Carlos M. Isales (3,6,7,8); Ulf M.E. Wike University College of Medicine (3) Engineering, Johns Hopkins School of Science Center, Texas (2); University of Engineered Nerve Grafts Consisting of Charlie Norwood Veterans Administration Manuel Jayo (1, 3), Deepak Jain (1) Hang Lin Medicine (2); Neurology and Neuroscience, 173 Washington, Seattle, Washington (3) Stretch-Grown Axons From Swine Medical Center, Augusta, Georgia (1); Tengion, Inc. (1); Organovo (2); Jayo, LLC (3) Projection Stereolithographic Fabrication Johns Hopkins School of Medicine (3) 196 of Bone Scaffold Encapsulated with Lenti- Brenton Burger Mindy I. Ezra; John A. Wolf; Kevin D. Laboratory for Applied Periodontal & Zeynep Karahaliloğlu Development of an Electrospun Poly-D-L- 179 Browne; Harry C. Ledebur; D. Kacy Cullen; Craniofacial Regeneration (2); Departments 203 BMP-2 transduced Human Bone Marrow 215 Nanofeatured Silk Membranes for Bone- Chandrasekhar Kothapalli Stem Cells (hBMSCs) Lactic Acid (PDLA), Polydioxanone (PDO) Catarina Custódio Douglas H. Smith of Cellular Biology and Anatomy (3); Oral Tissue Engineering Applications Michael McClure Microfluidic Device to Investigate the Effects Hang Lin (1); Ying Tang (2); Nicholas Oyster Utilizing Platelet Rich Plasma and Galectins and Chitin-Whiskers (CWs) Compressed, Functional Cell Selective Microparticles as Department of Neurosurgery, School of Biology (4); Biostatistics and Epidemiology Zeynep Karahalilo lu (1); Batur Ercan (2); ğ of Microenvironment on Axonal Outgrowth (3); Bing Wang (4); Rocky S. Tuan (5) to Create Skeletal Muscle Replacements Composite Membrane for Guided Bone Injectable Cell Carriers for Tissue Engineering Medicine, Center for Brain Injury and Repair, (5); Orthopaedic Surgery (6); and Institutes of Emir B. Denkba (3); Thomas J. Webster (4) ğ and Turning Orthopaedic Surgery, University of Pittsburgh Michael J. McClure (1,4); John J. Ryan (2); Regeneration Applications University of Pennsylvania Molecular Medicine and Genetics (7); and Nanotechnology and Nanomedicine James K. Deyling; Chandrasekhar R. (1) David G. Simpson (3); Gary L. Bowlin (4); Brenton W. Burger (1,2); Mark C. Bailey (1); Catarina A. Custodio (1,2); Rui L. Reis (1,2); Regenerative and Reparative Medicine (8); Division, Hacettepe University (1); Chemical Kothapalli Jeffery J. Ericksen (1) Craig O. Yates (1); Gary L. Bowlin (1); Joao F. Mano (1,2) 186 Georgia Regents University, Augusta, Georgia Engineering Department, Northeastern Department of Chemical and Biomedical 210 Physical Medicine and Rehabilitation, Hunter Biomedical Engineering, Virginia 3B’s Research Group - Biomaterials, Behzad Farshid University (2); Chemistry Department, Engineering, Cleveland State University, Chase Linsley Holmes McGuire Veterans Affairs Medical Commonwealth University (1); Dulles Biodegradables and Biomimetics, University Towards Nanoparticle Reinforced 191 Biochemistry Division, Hacettepe University (3) Mechanical Properties of and Mesenchymal Center (1); Biology, Virginia Commonwealth Cleveland, Ohio Institute for Oral, Maxillofacial and Implant of Minho, Portugal (1); ICVS/3B’s, PT Biodegradable Composites: Cytocompatibility Alexander Hodge Stem Cell Growth on Three-Dimensional University (2); Anatomy and Neurobiology, Surgery (2) Government Associated Laboratory, Braga/ of Inorganic Polypropyelene Fumarate Nitric Oxide Donors Improve Maturation of 197 Biomimetic Bone Scaffolds Virginia Commonwealth University Guimarães, Portugal (2) Nanocomposites Stem Cell-derived Cardiomyocytes Lohitash Karumbaiah 204 Chase Linsley (1); Roxana Fard (2); Benjamin (3); Biomedical Engineering, Virginia 174 Behzad Farshid; Gaurav Lalwani; Balaji Alexander J. Hodge (1); Juming Zhong (2); Chondroitin Sulfate Glycosaminoglycan Chandrasekhar Kothapalli Wu (1); Bill Tawil (1) Commonwealth University (4) Lian Cen 180 Sitharaman Dror Seliktar (3); Elizabeth A. Lipke (1) Hydrogels for Neural Stem Cell Matrix Microenvironment Regulates Bioengineering, University of California, Los Regeneration of Dentin-Pulp-Like Tissue using Bodhisatwa Das Department of Biomedical Engineering, Stony Chemical Engineering, Auburn University Transplantation Human Mesenchymal Stem Cell (HuMSC) Angeles (1); Biotechnology & Bioinformatics, 216 Nick Merna Injectable Tissue Engineering Technique Laser Patterned Nano Silver Doped Brook University (1); Veterinary Medicine, Auburn University Lohitash Karumbaiah; Syed Faaiz Enam; Differentiation into Neural Lineages California State University Channel Islands (2) Linhua Tan (1,2); Lian Cen (1,2,3); Shuo Yin Calcium Phosphate Scaffolds for Bone Graft (2); Biomedical Engineering, Technion-Israel Kurt W. Farrell; Chandrasekhar R. Kothapalli Collagen mRNA Transcription in Fibroblasts Tarun Saxena; Ravi Bellamkonda is Regulated by Substrate Stiffness and (2); Wei Liu (1,2); Yilin Cao (1,2) Application 187 Institute of Technology (3) Georgia Institute of Technology and Emory Department of Chemical and Biomedical 211 Engineering, Cleveland State University, Srinivas Madduri Composition Department of Plastic and Reconstructive Bodhisatwa Das (1); Prabhash Dadhich (1); Sunil George University School of Medicine, Atlanta, Nick J. Merna (1,2); Kelsey M. Fung (1,2); Surgery, Shanghai 9th People’s Hospital, Pallabi Pal (1); Pavan Kumar Srivas (1); Sujoy The Feasibility of Using Autologous Renal 192 Georgia Cleveland, Ohio Nanofibrous Nerve Conduits Releasing Collagen Binding GDNF for Axonal Growth Steven C. George (1,2) Shanghai Jiao Tong University School of Maiti (2); Pradeep Kumar Das Mohapatra (2); Cells From Diseased Kidneys for the Sharon Hyzy Department of Biomedical Engineering, Medicine (1); National Tissue Engineering Santanu Dhara (1) Treatment of Renal Failure MSCs Secrete Pro-Inflammatory Interleukins 198 205 and Guidance University of California, Irvine (1); Edwards Center of China (2); School of Chemical School of Medical Science and Technology, Sunil K. George; Mehran Abolbashari; Cheil in Response to Bone Morphogenetic Protein Timothy Keane Merlin Rajesh Lal L.P. Sandhya Ananta (2); Bruno Gander (1); Life Sciences Center for Advanced Hemmi Silvio (2); Daniel Kalbermatten (3); Engineering, East China University of Science Indian Institute of Technology, Kharagpur; Kim; John Jackson; Tamer Aboushwareb; 2 on Microstructured Titanium Recruitment of Site-Specific Progenitors with Dynamic Compression Loading Plays an Cardiovascular Technologies, University of Important Role in Chondrocytic Activity on Srinivas Madduri (1) and Technology (3) (1); Department of Microbiology, Vidyasagar Anthony Atala; James J. Yoo Sharon L. Hyzy (1); Sarah Ortman (2); an Esophageal Mucosal Biologic Scaffold California, Irvine (2) Goat Chondrocytes-Agarose Construct Department of Chemistry and Applied University (2) Wake Forest Institute for Regenerative Barbara D. Boyan (1); Zvi Schwartz (1,3); Timothy J. Keane (1,2); Ricardo Londono (1); Merlin Rajesh Lal L.P. (1); Suraisgkumar G.K. Biosciences, ETH Zurich, Switzerland 217 175 Medicine, Wake Forest School of Medicine, Rene Olivares-Navarrete (1) Aaron Deward (1); Stephen F. Badylak (1-3) (1); Prabha D. Nair (2) (1); Institute of Molecular Life Sciences, Prafulla Chandra 181 Winston-Salem, North Carolina Biomedical Engineering, Virginia McGowan Institute for Regenerative Nguyen Minh Khanh Department of Biotechnology, Indian Institute University of Zurich, Switzerland (2); siRNA Delivery from In Situ Forming Enhanced Tissue Regeneration using an Christopher deBorde Medicine (1); Department of Bioengineering, Commonwealth University, Richmond, of Technology Madras, Chennai, India Department of Plastic, Reconstructive and Degradable Hydrogels for Osteogenic Oxygen Producing Wound Dressing Development of a Novel Mitral Valve Scaffold Virginia (1); Biomedical Engineering, Georgia (2); Department of Surgery University of (1); Department of Tissue Engineering and Aesthetic Surgery, University Hospital Basel, Differentiation of Encapsulated hMSCs Prafulla Chandra; Christina Ross; Leona for a Tissue Engineered Solution Institute of Technology, Atlanta, Georgia (2); Pittsburgh, Pennsylvania (3) Regeneration Technologies, BMT Wing, Sree Switzerland (3) Minh K. Nguyen (1); Oju Jeon (1); Melissa Smith; Seon Jeong; Jaehyun Kim; James J. Yoo; Christopher deBorde (1); Agneta Simionescu Department of Periodontics, University of Chitra Tirunal Institute for Medical Sciences D. Krebs (2); Daniel S. Schapira (1); Eben Benjamin S. Harrison (2); Bioengieering, Clemson University Texas Health Science Center at San Antonio, 199 and Technology, Trivandrum, Kerala, India (2) Alsberg (1,3) Wake Forest Institute for Regenerative Texas (3) Allison Kennamer Biomedical Engineering, Case Wester Reserve Medicine, Wake Forest School of Medicine, Interstitial Cell Seeding and Conditioning of University (1); Chemical and Biological Winston-Salem, North Carolina Aortic Heart Valve Scaffolds Engineering, Colorado School of Mines (2); Allison R. Kennamer (1); Leslie N. Sierad (1); Orthopaedic Surgery, Case Wester Reserve Dan T. Simionescu (1) University (3) Bioengineering, Clemson University 28 29 POSTER SESSION I – MONDAY, NOVEMBER 11, 2013 4:30 – 6:00 PM POSTER SESSION I – MONDAY, NOVEMBER 11, 2013 4:30 – 6:00 PM

218 224 230 236 241 247 253 260 Neethu Mohan Timothy Pennel Daniel Roy Keisuke Takanari Lucy Vojtova Munetaka Yokoyama Lucas Hofmeister Sarawut Thepthong Biosignal Reservoir Embraced Substrates for Transmural Capillary Ingrowth is Essential for Release of Functional Antibiotics from a Muscle-Derived Stem Cell (MDSC) Growth Plate Cartilage Regeneration Using Platelet Activation Serum may have a Hemodynamic Targeting of Atheroprone In Vitro Aortic Reconstruction by Sandwich Enhanced Performance of Chondrocytes & Mid-graft Healing Keratin Hydrogel to Treat Cutaneous Wound Microintegrated Elastic Scaffolds for the Allogeneic Mesenchymal Stem Cells Seeded Therapeutic Effect on Articular Cartilage Vasculature for Preventative Treatment Model using Acellular Tissue and Collagen Stem Cells In Vitro Timothy Pennel (2); Deon Bezuidenhout (1); Infection Reconstruction of Abdominal Wall Defects on 3D Collagen/Chitosan Porous Scaffolds Munetaka Yokoyama(1); Masato Sato (1); Lucas Hofmeister (1); Sue Lee (1); Wei Chen Cell Sheets Neethu Mohan (1); Dexy Joseph (1); Dhanesh Neil Davies (1); Peter Zilla (1,2) Daniel Roy (1,2); David Burmeister (1); Keisuke Takanari (1,2,5); Yi Hong (1,2,6); Lucy Vojtova (1); Josef Jancar (1,2); Jana Yoshiki Tani (1); Miyuki Kobayashi (1); Mami (2); Todd D. Giorgio (1); David G. Harrison (2); Sarawut Thepthong; Toshia Fujisato Vaikkath (1); Geetha K. (1); Prabha D. Nair (1) Cardiovascular Research Unit, University of Hanyan Meng (3); Mary Ellenburg (2); Luke Ryotaro Hashizume (1,2,7); Nicholas J. Juhasova (3); Alois Necas (4); Michal Crha (4); Kokubo (1); Joji Mochida (1) Hak-Joon Sung (1) Biomedical Engineering, Osaka Institute of Division of Tissue Engineering and Cape Town (1); Department of Cardiothoracic Burnett (2); Seth Tomblyn (2); Justin Saul (3); Amoroso (1,3); Burhan Gharaibeh (1,4); Pavel Proks (4); Ladislav Planka (5) Department of Orthopaedic Surgical Science, Biomedical Engineering, Vanderbilt University Technology Regeneration Technologies, Sree Chitra Tirunal Surgery, University of Cape Town (2) Robert Christy (1) Kazuhiro Nonaka (1,2); Yuzuru Kamei (5); Central European Institute of Technology, Tokai University, School of Medicine (1) (1); Clinical Pharmacology, Vanderbilt Institute for Medical Sciences & Technology Extremity Trauma Research & Regenerative Johnny Huard (1,4); William R. Wagner (1,2,3) Brno University of Technology (1); Institute University (2) 261 225 Medicine, United States Army Institute of McGowan Institute for Regenerative of Materials Chemistry, Faculty of Chemistry, 248 Nicolas Christoforou 219 Swati Pradhan-Bhatt Surgical Research (1); KeraNetics, LLC (2); Medicine, University of Pittsburgh (1); Brno University of Technology (2); Laboratory Mousa Younesi 254 Assembling Functional Biosynthetic Tissues Marie Morille Culture of Human Salivary Gland Cells in Miami University (3) Department of Surgery, University of of cell regeneration and plasticity, Institute Mesenchymal Stem Cells Synthesize a Tendon- Richard Leask with Induced Pluripotent Stem Cell-Derived New PLGA-P188-PLGA Pharmacologically Hyaluronic Acid (HA)-Based Hydrogels for Pittsburgh (2); Department of Bioengineering, of Animal Physiology and Genetics AS CR Like Matrix in Woven Aligned Collagen Spatial Restricted Temporary Cell Cardiac Progenitor Cells Active MicrocarriersreleasingTGF-β3 and use in Tissue Engineering Applications 231 University of Pittsburgh (3); Department (3); Central European Institute of Technology, Scaffolds Permeablilization using an Inert Jet of Gas Nicolas Christoforou (1,2); Brian Liau (2); Conveying Mesenchymal Stem Cells Induce Swati Pradhan-Bhatt (1,2,5); Xian Xu (3); Meghan Samberg of Orthopaedic Surgery, University of University of Veterinary and Pharmaceutical Mousa Younesi (1); Anowarul Islam (1); Vipuil Richard L. Leask (1); Paul Jonak (1); Scott Syandan Chakraborty (2); Malathi Chellapan Cartilage-like Tissue Formation Daniel A. Harrington (6); Eliza Fong (6); Effect of Platelet Incorporation within Human Pittsburgh (4); Department of Plastic and Sciences Brno (4); Clinic of Pediatric Surgery, Kishore (1); Ozan Akkus (1, 2, 3); Cooper (1) (2); Nenad Bursac (2); Kam W. Leong (2) Marie Morille (1,2): Marie-Claire Venier- Xinqiao Jia (3,4); Robert Witt (1,2,5); and Mary Plasma Hydrogels on Human Adipose-derived Reconstructive Surgery, Nagoya University Orthopaedics and Traumatology, Faculty of Department of Mechanical and Aerospace Department of Chemical Engineering, McGill Department of Biomedical Engineering, Julienne (1); Xavier Garric (3); Danièle Noël C. Farach-Carson (1,2,6) Stem Cell Differentiation Graduate School of Medicine (5); Department Medicine, Masaryk University (5) Engineering, Case Western Reserve University University (1) Khalifa University, Abu Dhabi (1); Department (2); Claudia N. Montero-Menei1 Departments of Biological Sciences (1); The Meghan E. Samberg (1); Sandra C. Becerra (1); of Bioengineering, University of Texas at (1); Department of Biomedical Engineering, of Biomedical Engineering, Duke University, 1-LUNAM Université, UMR-S1066; INSERM, Center for Translational Cancer Research (2); Andrew P. Cap (2); Robert J. Christy (1) Arlington (6); Department of Pathology and 242 Case Western Reserve University (2); 255 Durham (2) U1066, F-49933 Angers, France 2-INSERM Materials Science & Engineering (3); and Extremity Trauma and Regenerative Medicine, Matrix Biology, Mie University Graduate Jia-Lun Wang Department of Orthopedic Surgery, Case Gerson Acasigua U844, F-34091 Montpellier, France 3-Institut Biomedical Engineering (4); University of United States Army Institute of Surgical School of Medicine (7) Decellularized Human Placental Vascular School of Medicine, Case Western Reserve Physico-chemical Analysis of Electrospun 262 des biomolécules Max Mousseron, CNRS Delaware, Helen F. Graham Cancer Center, Research, Fort Sam Houston, Texas (1); Scaffold Supports Repopulation of Human University (3) Scaffolds Increased by Dexamethasone Sarah Sundelacruz UMR 5247, Montpellier, France Christiana Care Health Systems, Newark, Coagulation and Blood Research, Fort Sam 237 Primary Hepatocytes In Vitro and In Vivo Gerson A.X. Acasigua (1); Patricia Pranke 3D Tissue Repair Model for Studying Delaware (5); Department of Biochemistry Houston, Texas (2) Yoshiki Tani Jia-Lun Wang; Qian Ye; Xuan Guo; Xiaowei 249 (2, 3,4); Daikelly I Braghirolli (2,4); Douglas Bioelectric Signaling During Bone Wound 220 and Cell Biology, Rice University, Houston, Diagnosis for Degenerative Articular Cartilage Deng; Uri Herzberg; Mohit B. Bhatia; Elie Zakhem Gamba (5); Anna C.M. Fossati (1) Healing Naoko Nakamura Texas (6) 232 Using Non-destructive Pulsed Laser Irradiation Wolfgang T. Hofgartner; Robert J. Hariri A Tissue Engineered Esophageal Construct Post-graduate Program in Dentistry (1); Sarah Sundelacruz (1); Chunmei Li (1); Young Microenvironment of Decellularized Bone Maryellen Sandor Yoshiki Tani (1); Masato Sato (1); Munetaka Celgene Cellular Therapeutics Demonstrates Physiological Functionality In Hematology and Stem Cell Laboratory, Faculty Jun Choi (1); Michael Levin (2); David L. Marrow for HSPC Homing 226 Comparison of Human Acellular Dermal Yokoyama (1); Tomonori Takagaki (1); Miyuki Vitro of Pharmacy (2); Post Graduate Program in Kaplan (1) Naoko Nakamura (1); Kwangwoo Nam (1); Marco Quarta Matrices Used in Reconstructive Surgery Kobayashi (1); Mami Kokubo (1); Goro Elie Zakhem (1,2); Khalil N. Bitar (1,2) Physiology (3); Stem Cell Research Institute (4); Department of Biomedical Engineering, Tsuyoshi Kimura (1); Toshiya Fujisato (2); Artificial Muscle Stem Cell Niche for In Vivo Maryellen Sandor (1); Marianne Edwards (1); Ebihara (1); Satoshi Ito (1); Taku Ukai (1); Miya 243 School of Biomedical Engineering and Chemistry Institute, Porto Alegre, Rio Grande Tufts University, Medford, Massachusetts Hiroo Iwata (2); Akio Kishida (1) Volumetric Tissue Engineering Eric Stec (1); Patrick G. De Deyne (1) Ishihara (2); Joji Mochida (1) Xintong Wang Sciences, Virginia Tech-Wake Forest (1); do Sul, Brazil (5) (1); Department of Biology and Center for A Thermo-Responsive, Self-Adhesive Institute of Biomaterials and Bioengineering, Marco Quarta (1,2); Melinda Cromie (1,2); LifeCell Corporation, Bridgewater, New Jersey (1); Department of Orthopaedic Surgical Institute for Regenerative Medicine, Wake Regenerative and Developmental Biology, Injectable Heart Scaffold for Pluripotent Stem 256 Tokyo Medical and Dental University (1); Robert Chacon (1,2); Michael Gibbons (1,2); (1) Science,Tokai University, School of Forest Baptist Health (2) Tufts University, Medford, Massachusetts (2) Cell-Derived Cardiomyocyte Delivery Katia Jarquín-Yáñez Faculty of Engineering, Osaka Institute of Antoine De Morree (1,2); Rebecca di Marco Medicine (2); Department of Medical Xintong Wang (1); Lin Zhong (2); Young Wook 250 Porosity Evaluation of Gelatin Scaffold made Technology (2) (3); Sarah Heilshorn (3); Thomas A. Rando 233 Engineering,National Defense Medical 263 Chun (1,2); Chee Lim (2); Charles Hong (2); David Zamora of Different Hyaluronic Acid Densities (1,2) John Scott College Marcella Vaicik Simon Maltais (3); Hak-Joon Sung (1,2) The Effects of Magnetic Nanoparticles on Katia Jarquin (1); Miguel Herrera (1); Beatriz 221 Department of Neurology, School of Development of a Novel Tissue Engineered Hydrogel Stiffness and Degradation Regulate Department of Biomedical Engineering, Human Corneal Epithelial Cell Viability. Hernandez (1); Gabriela Piñon (1); Rosa Alliny Naves Medicine, Stanford University (1); Center Muscle Repair Construct with Potential for Adipose Expansion In Vitro 238 (1); Carciovascular Medicine and (2); David O. Zamora (1,2); Mauris N. DeSilva Arellano (1); Daniel Santillan (1); Jesús Arenas Biocompatibilization of Polyesters Scaffolds for Tissue Regeneration, Restoration and Marcella K. Vaicik (1,2); Sonja Sokic (1); Enhanced Motor End Plate Formation and Lesley-Anne Turner Cardiac Surgery, Vanderbilt University, (1,3); Randolph D. Glickman (4); Heuy- (2); Armando Zepeda (1); Sandra Acevedo (1); using LbL as Reservoirs for bFGF Georgia Papavasiliou (1); Eric M. Brey (1,2); Repair (CTR3), VAPAHCS (2); Department of Function A Biomaterials Approach to Treating Age- Nashville,Tennessee (3) Ching H. Wang (1, 2); Dallas J. Golden (1,2); Andrés Castell (1); Alliny Ferreira Naves (1); Marvin Motay (1); Materials Science and Engineering, Stanford John B. Scott (1,2); Benjamin T. Corona (3); Related Macular Degeneration Biomedical Engineering, Illinois Institute of Anthony J. Johnson (1,2) School of Medicine UNAM, México City, Technology (1); Research Service, Edward Luiz Henrique Catalani (2); Gero Decher(1) University (3) Catherine L. Ward (3); Benjamin S. Harrison Lesley-Anne Turner (1); Erin M. S. Baggaley (1) 244 United States Army Institute of Surgical Mexico (1); Institute of Physics, UNAM, Hines Junior Veterans Affairs Hospital, Hines, Institute Charles Sadron, Centre National de (1,2); Justin M. Saul (4); George J. Christ (1,2) School of Materials, Faculty of Engineering Catherine Ward México City, Mexico (2) Research, Fort Sam Houston, Texas (1); Illinois (2) la Recherche Scientifique (1); Instituto de 227 Wake Forest Institute for Regenerative and Physical Sciences, University of Development of an Injectable and Settable Department of Ocular Trauma & Vision Química, Universidade de São Paulo (2) Raj Rao Medicine (1); Virginia Tech - Wake Forest Manchester (1) Polyurethane Cell Delivery System for Tissue Restoration (2); Naval Medical Research Unit 257 264 Silk Fibroin Aerogels For Mammalian Cell School of Biomedical Engineering and Regeneration (3); University of Texas Health Science Center, Chelsea Kirschner Mathew Varkey 222 Culture And Tissue Engineering Applications Sciences (2); United States Army Institute 239 Catherine L. Ward (1); Ruijing Guo (2); Joseph Department of Ophthalmology, San Antonio, Clickable, Photodegradable Hydrogels to Chan Ho Park Vasudha Surampudi; Rajendar R. Mallepally; for Surgical Research (3); Miami University Dhanesh V C. Wenke (1); Scott A. Guelcher (2) Texas (4) Dynamically Modulate Valvular Interstitial Superficial Dermal Fibroblasts Enhance Periodontal-Mimic Gelatin Scaffold to Guide Michael A. Marin; Mark A. McHugh; Raj R. School of Engineering and Applied Science (4) An In Vitro Evaluation of Natural Extremity Trauma and Regenerative Medicine Cell Phenotype Basement Membrane and Epidermal Barrier Periodontal Ligament Regeneration and Rao Glycosaminoglycan Polymer Based Injectable Task Area, United States Army Institute 251 Chelsea M. Kirschner (1,3); Daniel L. Alge ( Formation in Tissue Engineered Skin Organization Department of Chemical and Life Science 234 Photopolymerisable Hydrogel for Cartilage of Surgical Research, Fort Sam Houston, Michael Zimber 1-3); Sarah T. Gould (1,3); Kristi S. Anseth (1-3) Mathew Varkey (1); Jie Ding (1); Edward Chan Ho Park (1); Kyoung-Hwa Kim (1); Engineering, Virginia Commonwealth Jeeva Sellathurai Tissue Engineering Texas (1); Department of Chemical and Human Multipotent Stem Cell Proteins Department of Chemical and Biological Tredget (1,2) Hector F. Rios (2); William V. Giannobile (2,3); University, Richmond, Virginia Esophagus Reconstruction using Dhanesh V.; Babitha S.; Bindu P. Nair; Biomolecular Engineering, Vanderbilt Support Osteogenesis In Vitro Engineering (1); Howard Hughes Medical Division of Plastic and Reconstructive Surgery Yong-Moo Lee (1); Yang-Jo Seol (1) Electrospinned PCL Scaffolds and Human Prabha D. Nair University, Nashville, Tennessee (2) Michael Zimber (1); Emmett Pinney (1); Institute, and the (2) Biofrontiers Institute, (1); University of Alberta; Division of Critical Department of Periodontology, School of 228 Smooth Muscle Cells Division of Tissue Engineering and Samantha Reiss (1); Gail K. Naughton (1,2) University of Colorado, Boulder, Colorado (3) Care Medicine (2); University of Alberta Dentistry, Seoul National University, Seoul Jennifer Robinson Jeeva Sellathurai (1); Rua Al-Bader (1); Pernille Regeneration Technologies, Sree chitra 245 Histogen, Inc., San Diego, California (1); PUR South Korea (1); Department of Periodontics Injectable Foams for the Delivery of Diemer (2); Prabha D. Nair (3); Niels Qvist (2); Tirunal Institute for Medical Sciences and Corin Williams Biologics, Aliso Viejo, California (2) 258 and Oral Medicine, School of Dentistry, Autologous Mesenchymal Stem Cells Thomas Ledet (4); Henrik D. Schrøder (1,5). Technologies, Kerala Cardiac Extracellular Matrix-Fibrin Hydrogel Johnny Lam 265 University of Michigan, Ann Arbor (2); Jennifer L Robinson (1); Robert S Moglia (1); Institute of Clinical Research, SDU Muscle Scaffolds with Tunable Properties for Cardiac Articular Chondrocyte and Mesenchymal Gilson Khang Department of Biomedical Engineering, Melissa C Stuebben (1); Madison A P McEnery Research Cluster, University of Southern 240 Tissue Engineering Stem Cell Co-cultures in Hydrogels for Influence of MSCs on the Response of ECs to College of Engineering, University of (1); Elizabeth Cosgriff-Hernandez (1) Denmark, Odense, Denmark (1); Surgical Lynda Velutheril Thomas Erica Budina (1); Corin Williams (1); Sirisha Osteochondral Tissue Engineering Laminar Flow and Shear Stress Michigan, Ann Arbor, Michigan (3) Department of Biomedical Engineering, Texas Department A, Odense University Hospital, An “Artificial Nanofibrous Niche” Supporting Emani (2), Sitaram Emani (2); Lauren D. Black Johnny Lam (1); Rebecca L. Dahlin (2); Steven Hyeongseok Kim (1); Minsung Hong (1); Agricultural & Mechanical University Odense, Denmark (2); Division of Tissue the Differentiation of Adipose Stem Cells III (1) Lu (3); Yasuhiko Tabata (4); Antonios G. Mikos Hansu Jo (1); Randall F. Ankeny (2); Casey J. 223 Engineering and Regeneration Technologies, to Smooth Muscle Cells under Pulsatile Biomedical Engineering, Tufts University (1); (5); F. Kurtis Kasper (6) Holliday-Ankeny (2); Gilson Khang (1); Robert Janki Patel 229 Sree Chitra Tirunal Institute for Medical Condition Cardiac Surgery, Children’s Hospital Boston (2) LATE BREAKING POSTERS Department of Bioengineering, Rice University M. Nerem (1, 2) Binding Bone Morphogenetic Protein-2 to Scott Robinson Sciences and Technology, Trivandrum, India Lynda Velutheril Thomas(1); Surya S.(1); (1); Department of Biomaterials, Institute for Department of BIN Fusion Technology, Polycaprolactone in a Clinically Applicable A Fibrin-rich Platelet Lysate Scaffold Promotes (3); Department of Biochemical Pathology, Prabha D. Nair (1) 246 252 Frontier Medical Sciences, Kyoto University (2) Department of PolymerNano Science & Setting Invasion of Human Mesenchymal Stem Cells Aarhus University Hospital, Aarhus, Denmark Division of Tissue Engineering and Kelvin Yeung Teja Guda Technology and Polymer BIN Research Janki J. Patel (1); Colleen L. Flanagan (1); Scott T. Robinson (1); Ian B. Copland (2); Todd (4) Department of Pathology, Odense Regeneration Technologies, Biomedical Surface Modified 3D Porous and Nano- Enhancing Bone Regeneration in Large Bone 259 Center, Chonbuk National University Jeonju, Dongxia Ye (2); Matthew B. Wheeler (3); Sean C. McDevitt (3); Alexandra Peister (4); Luke P. University Hospital, Odense, Denmark (5) Technology Wing, Sree Chitra Tirunal Institute structured Polyetheretherketone (PEEK) For Defects Using Structural Hydroxyapatite Ngoc Nhi Le Chonbuk, Korea (1); Parker H. Petit Institute P. Edwards (2), Scott J. Hollister (1) Brewster (3,5,6) for Medical Sciences and Technology, Bone Tissue Engineering Compared to INFUSE® Hydrogel Array for Combinatorial Screening of for Bioengineering and Bioscience, Georgia Biomedical Engineering, University of MD/PhD Program, Emory University School 235 Thiruvananthapuram, Kerala, India (1) Y Zhao (1); HM Wong (1); P Li (2); Z Xu (3); Teja Guda (1,2); Stefanie M. Shiels (2); Suyash Stem Cell Behavior Institute of Technology (2) Michigan, Ann Arbor (1); Oral & Maxillofacial of Medicine (1); Hematology and Medical Lucilia Silva YW Chong (1); PK Chu (2) KWK Yeung (1) Karajgar (1); Joseph C. Wenke (2); Joo L. Ong Ngoc Nhi T. Le (1); Stefan Zorn (2); William L. Surgery, University of Michigan, Ann Arbor Oncology, Emory University School of Engineering Cell-adhesive Gellan Gum Department of Orthopaedics & Traumatology, (1) Murphy (3) (2); Animal Sciences, University of Illinois at Medicine (2); Biomedical Engineering, Spongy-like Hydrogels The University of Hong Kong, Pokfulam Road, Biomedical Engineering, University of Texas Materials Science Program, University Urbana-Champaign (3) Georgia Institute of Technology (3); Biology, Lucília da Silva (1); Mariana T. Cerqueira Hong Kong (1); Department of Physics and at San Antonio (1); Extremity Trauma and of Wisconsin-Madison (1); Biomedical Morehouse College (4); Vascular Surgery, (2); Rui A. Sousa (3); Rui L. Reis (4); Vitor M. Materials Science, City University of Hong Regenerative Medicine, United States Army Engineering, University of Wisconsin-Madison Emory University School of Medicine (5); Correlo (5); Alexandra P. Marques (6) Kong, Tat Chee Avenue, Kowloon, Hong Kong Institute of Surgical Research (2) (2); Orthopedics and Rehabilitation, University Atlanta Veterans Affairs Medical Center (6) 3B’s Research Group - Biomaterials, (2); Ministry-of-Education Key Laboratory of Wisconsin-Madison (3) Biodegradables and Biomimetics, University for the Green Preparation and Application of Minho (1), ICVS/3B’s - PT Government of Functional Materials, College of Materials Associate Laboratory, Braga/Guimarães, (2) Science and Engineering, Hubei University, Wuhan, PR China (2) 30 31 POSTER SESSION I – MONDAY, NOVEMBER 11, 2013 4:30 – 6:00 PM POSTER SESSION II – TUESDAY, NOVEMBER 12, 2013 2:30 – 4:00 PM

266 271 276 281 ACELLULAR THERAPIES 106 112 118 Miguel Herrera-Enríquez Sandy Lin Patricia Pranke Nadia Vázquez Christopher Dearth Tae Ho Kim Mark Tatterton Activation of Osteoblasts Chondroblasts and Organic Solvent-Free Polymeric Scaffolds for Association of Nanotechnology with Stem Biocompatibility of a Chitosan (CTS) - 100 The Effect of Terminal Sterilization on Material Treatment of Hearing Loss Using Ion- Tissue Engineering a Small Diameter Cell Fibroblasts Derived From Human Stromal Tissue Engineering Applications Cells to be used in Third Degree Burn Animal Polylactic Acid (PLA) Based Scaffold for Amit Aurora Properties and In Vivo Remodeling of a complexed Drug-loaded Hydrogel Seeded Vascular Graft Bone Marrow Cells, Seeded on Cadaveric Sandy T.C. Lin (1); David Musson (2); Debes Models the Development of a Biological Dermal Efficacy of Extracellular Matrix Scaffold for the Porcine Dermal Biologic Scaffold Tae Ho Kim (1); Jae-Jun Song (2); Se Heang Dr. Mark Tatterton (1); Dr. Stacy-Paul Wilshaw Demineralized Human Cancellous Bone Bhattacharyya (1); Jillian Cornish (2) Patricia Pranke (1,2,4); Daniela Steffens (1,2); Substitute Functional Restoration of Musculotendinous Christopher Dearth (1,2); Christopher Oh (3); Jin Ho Lee (1) (2); Professor Eileen Ingham (2); Professor Scaffold (Biosponge-Novoinjertos). Centre for Advanced Composite Materials, Dilmar Leonardi (1); Paula R. da L. Soster Nadia Vázquez (1,2); Andres Espadín (3); Junction Injury Carruthers (1,3); Janet Reing (1); Christian Department of Advanced Materials, Shervanthi Homer-Vanniasinkam (1); Miguel Herrera(1); Beatriz Hernández (1); Department of Mechanical Engineering, The (3); Michelle Lersch (1); Annelise Rosa (1); Keiko Shirai (3); Lenin Tamay (2); Lilia Solis Amit Aurora (1); Benjamin Corona (1); Janet Ranallo (1); Elizabeth Kollar (1); Peter Crapo Hannam University (1); Deptartment Leeds Vascular Institute, Leeds General Judith Alvarez (1); Gabriela Piñon (1); Katia University of Auckland (1); Department of Thayane Crestani (1); Cristiane Scher (1); (2); Antonio Medina (4); Cristina Velasquillo Roe (1); Thomas Walters (1) (1,2); Scott Johnson (1); Stephen Badylak (1-3) of Otorhinolaryngology, Dongguk Infirmary, Leeds, United Kingdom (1); Institute Jarquin (1); Sandra Acevedo (1); Pablo Castell Medicine, The University of Auckland (2) Michele G. de Morais (5); Jorge A.V. Costa (5) (2). Extremity Trauma Research Division, United McGowan Institute for Regenerative University Ilsan Hospital (2); Department of Medical and Biological Engineering, (2); Sergio Guevara (2); Teofilo Bandera (2); Hematology and Stem Cell Laboratory, National Autonomus University of Mexico (1) States Army Institute of Surgical Research (1) Medicine, University of Pittsburgh (1); of Nanobiomedical Science, Dankook University of Leeds, Leeds, United Kingdom Raul Flores (3); Francisco Limon (3); Enrique 272 Faculty of Pharmacy (1); Post Graduate Biotechnology Laboratory, National Institute Department of Surgery, University of University (3) (2) Obermeier( 3); Agustin Carrillo (3); Xin Lin Program in Physiology (2); Department of Rehabilitation (2) Biopolímers Laboratory, 101 Department of Cell and Tissue Biology, Implantable Extracellular Matrix Bioscaffold Pittsburgh (2); Department of Bioengineering, of Morphological Science (3); Federal Metropolitan Autonomus University (3) Stephen Badylak Medicine School, Universidad Nacional Augmented with Mesenchymal Stromal Cells University of Rio Grande do Sul; Stem Cell General Surgery Department, National University of Pittsburgh, Pennsylvania (3) 113 119 Biologic Scaffolds Composed of Extracellular Autónoma de México (1); General Hospital, for Cardiac Repair Research Institute (SCRI) (4) ; Porto Alegre, RS; Institute of Pediatrics (4) Joydip Kundu Maxime Tondreau ISSSTE, and Sanatorio de Padre Jesús, Iguala, Xin Lin; Tye Petrie; W. Douglas Boyd; Claus S. Laboratory (5) Matrix Promote a Constructive Macrophage 107 Decellularized Retinal Matrix as Substrate for Characterisation of an Entirely Biological Phenotype Gro. México (2); Tissue Bank Novoinjertos, Sondergaard 282 Timothy Ganey Delivery of Human Retinal Progenitor Cells Tissue-Engineered Fibroblast-derived Scaffold Brian M. Sicari, (1,2); Jenna Dziki (1); México City, México (3) Department of Surgery, University 277 Daniel Youngstrom Exploiting Truss Geometry as an Acellular Joydip Kundu (1); Andrew Michaelson (1); for Vascular Applications Christopher L. Dearth (1,2); Stephen F. of California, Davis, Medical Center, Patricia Pranke Mechanical Strain Induces Equine Adjuvant to Spine Fusion Kristen Talbot (1); Petr Baranov (2), Michael J. Maxime Tondreau (1,3); Véronique Laterreur Badylak (1,3,4) 267 Sacramento, California Mensenchymal Stem Cells and their use in Mesenchymal Cell Differentiation Toward Timothy Ganey (1); Lisa Ferrara (2); Peggy Young( 2) and Rebecca L. Carrier (1) (2,3); Karine Vallières (3) Jean-Michel Bourget McGowan Institute for Regenerative Gilson Khang the Reconstruction of Thyroid Cartilage using Tendon and Increases Matrix Strength Lalor (3); Jessee Hunt (4) Chemical Engineering, Northeastern (1,3); Dan Lacroix (3); Jean Ruel (2,3); Lucie Medicine (1); Department of Pathology Growth Behavior of Corneal Endothelial Cells 273 Nanofibers as Scaffolds Daniel W. Youngstrom (1); Jennifer G. Barrett Orthopaedic Surgery, Atlanta Medical Center University, Boston, Massachusetts (1); Germain (1,3); François A. Auger (1,3) (2); Department of Surgery University of on Silk Substrata Ashwin Nair Patricia Pranke; Geraldo P. Jotz; Paula (1); Shannon L. Smith (2); Jonathan A. Kluge (1); OrthoKinetic, LLC (2); Histion, LLC (3); Schepens Eye Research Institute, an Affiliate Department of Surgery, Laval University (1); Pittsburgh, Pittsburgh, Pennsylvania (3); Seung Chang Oh (1); Cheon Jung Lee (1); Autologous Stem Cell-derived Bone Tissue Rigon da Luz Soster; Carlos Afonso Beck; (2); David L. Kaplan (2) 4WEB, Inc. (4) of , Boston, Department of Mechanical Engineering, Laval Department of Bioengineering University of Min Ju Na (1) Jin Young Park (1); Eun Young Engineering in Peritonea Marcelo Muccilo; Daniela Steffens; Daikelly Marion duPont Scott Equine Medical Center, Massachusetts (2) University (2); Laval University LOEX Center Pittsburgh, Pittsburgh, Pennsylvania (4) Kim (1); Jeong Eun Song (1); Choun-Ki Joo Jinhui Shen (1); Ashwin M. Nair (1); I. Braghirolli; Rui Fernando Felix Lopes; Virginia Tech (1); Tissue Engineering Resource 108 - Regenerative Medicine Axis of the FRQS (2); Dongwon Lee (1); Gilson Khang (1) Chengcheng Zhang (2); Ramesh Saxena (3); Bernardo Mastella Center, Tufts University (2) Jose Garcia 114 Quebec City CHU Research Center (3) Department of BIN Fusion Technology, Liping Tang (1) Hematology and Stem Cells Laboratory, 102 Enhanced Therapeutic Effects of PEG Fanwei Meng Department of PolymerNano Science & Bioengineering, University of Texas Faculty of Pharmacy; Federal University of Alexander Baume Hydrogels Functionalized with VEGF and a Effect of Extracellular Matrix Bioscaffolds on 120 Technology and Polymer BIN Research Southwestern Medical Center and University Grande do Sul; Post Graduate Program in Development of an Antibacterial-Eluting Bi- Collagen-mimetic Adhesive Peptide for Bone Microglia Phenotype Mujib Ullah Center, Chonbuk Natl Univ, Jeonju, Chonbuk, of Texas at Arlington (1); Physiology and Physiology; Federal University of Grande do Phasic Scaffold for Wound Healing Defects Fanwei Meng (1,2,3); Christopher Medberry Genomic and Proteomic Analysis of Korea (1); Department of Ophthalmology Developmental Biology, University of Texas Sul; Morphological Science Department; Alexander S. Baume (1); Philip C. Boughton Jose R. Garcia (1); Amy Y. Cheng (2); Andres (1,2); Christopher L. Dearth (1,2,3); Stephen F. Extracellular Fat Matrix Reveals a Uniform and Visual Science, College of Medicine, The Southwestern Medical Center (2); Internal Federal University of Grande do Sul (1); Nicholas V. Coleman (2); Susan V. J. Garcia (3) Badylak(1,2,3) Structural and Functional Network for Catholic University (2) Medicine, University of Texas Southwestern McLennan (3); Andrew J. Ruys (1) Woodruff School of Mechanical Engineering, McGowan Institute for Regenerative Cellular Interactions Medical (3) 278 Biomedical Engineering, School of Georiga Institute of Technology (1); Institute Medicine, University of Pittsburgh (1); Mujib Ullah; Stefan Stich; Yvonne Wloka; 268 Patricia Pranke Aerospace, Mechanical & Mechatronic for Bioengineering and Biosciences, Georgia Department of Surgery, University of Sarah Sommerkamp; Michael Sittinger and Gilson Khang 274 Physico-chemical Analysis of Electrospun Engineering, University of Sydney, Australia Institute of Technology (2) Pittsburgh (2); Department of Bioengineering, Jochen Ringe Biological Characterization through a Variety Thomas Nau Scaffolds Increased by Dexamethasone (1); School of Molecular & Microbial University of Pittsburgh (3) Tissue Engineering Laboratory and Berlin- of Formulation of High and Low Acyl Gellan In Vivo Results of a Regenerated Anterior Patricia Pranke (1,2,3); Gerson A.X. Acasigua Biosciences, University of Sydney, Australia 109 Brandenburg Center for Regenerative Gum Cruciate Ligament Using a Novel Silk-Fiber (4); Daikelly I. Braghirolli (1,3); Douglas (2); Sydney Medical School, University of Hye Yun Kim (1); So Jin Lee (1); Young Lae Based Scaffold Device David Giraldo Gomez 115 Therapies, Department of Rheumatology Gamba (5); Anna C.M. Fossati (4) Sydney, Australia (3) Kim (1); Eun Young Kim (1); Jeong Eun Song Andreas H. Teuschl; Sylvia Nürnberger; Hematology and Stem Cell Laboratory, Characterization of a New Scaffold Obtain Amanda Miller and Clinical Immunology, Charité-University (1); Rui. L. Reis (2); Gilson Khang (1) Martin Mayer; Pavol Szomolanyi; Siegfried Faculty of Pharmacy (1); Post Graduate by Enzymatic Treatment for Engineering MatrACELL® Pulmonary Artery Allograft Medicine Berlin, Charitéplatz,Berlin, Department of BIN Fusion Technology, Trattnig; Heinz Redl; Thomas Nau Program in Physiology (2); Stem Cell 103 Cartilage for Cardiovascular Repairs Compared to Germany Department of PolymerNano Science & University of Applied Sciences Technikum Research Institute (3); Post-graduate Program Charito Buensuceso David M. Giraldo Gomez (1); David Porcine Small Intestinal Submucosa with Technology and Polymer BIN Research Wien, Vienna, Austria - City of Vienna in Dentistry (4); Chemistry Institute, Porto Effects of Acellular Dermal Matrix Extracts on Garciadiego Cazares (2); Cristina Piña Barba Respect to its Extent of Decellularization and 121 Center, Chonbuk National University, Competence Team Tissue Engineering Alegre, Rio Grande do Sul, Brazil (5) the Migration and Proliferation of Endothelial (3) Extracellular Components Lisa White Jeonju, Chonbuk, Korea (1) 3B’s Research Bioreactors; The Austrian Cluster for Tissue Cells Instituto de Investigaciones en Materiales, Amanda Houck Miller (1); Alyce Linthurst Hydrogels Derived from Demineralized and Group-Biomaterials, Biodegradables and Regeneration, Vienna, Austria; Ludwig 279 Charito Buensuceso (1); Nalinai Scott (1); Universidad Nacional Autónoma de México Jones (1) Decellularized Bone - Novel Materials for Biomimetics, University Minho (2) Boltzmann Institute for Experimental and Patricia Pranke Sean Collins (1); Patrick G. De Deyne (1) (1); Unidad de Ingeniería de Tejidos Terapia Research and Development, LifeNet Health Bone Regeneration Clinical Neural Differentiation of Mesenchymal LifeCell Corporation (1) Celular y Medicina Regenerativa, Instituto (1) Lisa J. White (1); Stephen F. Badylak (2); Kevin 269 Stem Cells Cultivated on Aligned Nanofiber Nacional de Rehabilitación (2); Instituto de M. Shakesheff (1) Gilson Khang 275 Scaffolds 104 Investigaciones en Materiales, Universidad 116 School of Pharmacy, University of Characterization of Collagen and Patricia Pranke Patricia Pranke (1,2); Thayane Crestani (1); Alonzo Cook Nacional Autónoma de México (3) Nima Momtahan Nottingham (1); McGowan Institute for Hydroxyapatite Coated Silk for Application in Novel Chemically Modified Bacterial Kerlin Quintiliano (1); Virginia E. Helfer (1); Optimization of Decellularization Processes Novel Thrombogenicity Analysis of Regenerative Medicine, University of Biomedical Materials Cellulose Nanocomposite as Potential Davi S. Santos (1); Eduardo A. Balbueno (1); for Renal Structures 110 Decellularized Cardiac Organs Pittsburgh (2) Jeong Eun Song (1); Seung Chang Oh (1); Biomaterial for Stem Cell Therapy Estela M. Cruvinel (3); Antonio C. Cassola (3); Jeffery J. Nielson (1); Brent D. Young (2); Li Ting Huang Nima Momtahan (1); Sivaprasad Jeawon Yang (1); Hye Yoon Kim (1); Eun Applications Diogo A. Pilger (1); Geraldo Jotz (4) Brendan G. Ashton (3); Cory A. Fronk (2); Development of In Vitro Assays to Measure Sukavaneshvar (2); Beverly L Roeder (3); CELL ENGINEERING/SYNTHETIC Young Kim (1); Chan Hum Park (2); Gilson Patricia Pranke; Gerson Arisoly Xavier Hematology and Stem Cell Laboratory, Grant W Holden (2); Jonathan J. Wisco (4); Acellular Matrix Induced Inflammatory Jeffery R Barrow (4); William G Pitt (1); BIOLOGY Khang (1) Acasigua; Gabriel Molina de Olyveira; Ligia Faculty of Pharmacy (1) ;Stem Cell Research Jeffery R. Barrow (4); Beverly L. Roeder (5); Responses Alonzo D Cook (1) Department of BIN Fusion Technology, Maria Manzine Costa; Daikelly Iglesias Institute (SCRI); Porto Alegre, RS (2); Alonzo D. Cook (2) Li Ting Huang (1); Hua Wan (1); Hui Xu (1) Chemical Engineering, Brigham Young 122 Department of PolymerNano Science & Braghirolli; Anna Christina Medeiros Fossati; Biosciences Institute, Federal University of Biochemistry, Brigham Young University Research & Development, LifeCell University (1); Thrombodyne, Incorporated Hyunhee Ahn Technology and Polymer BIN Research Antonio Carlos Guastaldib; Pierre Basmaji São Paulo (3); Department of Morphological (1); Chemical Engineering, Brigham Young Corporation (1) (2); Biology, Brigham Young University (3); Fabrication of Small Diameter Vascular Grafts Center, Chonbuk National University, Jeonju, Hematology and Stem Cell Laboratory, Sciences; Federal University of Rio Grande (4) University (2); Biophysics, Brigham Young Physiology and Developmental Biology, by Combining Cell Sheet Engineering and Chonbuk, Korea (1); Otorhinolaryngology- Faculty of Pharmacy; Post Graduate Program University (3); Physiology and Developmental 111 Brigham Young University (4) Electrospinning Technology Head and Neck Surgery, Chuncheon Sacred in Physiology; Stem Cell Research Institute; 280 Biology, Brigham Young University (4); Jason Inzana Hyunhee Ahn (1); Young Min Ju (2); Hironobu Heart Hospital, Collage of Medicine (2) Post-graduate Program in Dentistry, Porto Kazuya Sawada Biology, Brigham Young University (5) 117 Takahashi (2);Teruo Okano (1); James J. Yoo Alegre, Rio Grande do Sul; Department of Fabrication of the Keratin Protein Scaffold for Design & Characterization of 3D Printed 270 Physical Chemistry, Araraquara Collagen-Calcium Phosphate Composites for Michael Raxworthy (1); Anthony Atala (1); Sang Jin Lee (1) Chondrocyte Cultivation 105 Gilson Khang Kazuya Sawada (1,2); Hiroki Goto (3); Toshiya Bone Defect Repair Performance In Vivo of EktoTherix, a Synthetic Wake Forest Institute for Regenerative Gabriella Dahlgren The Effect of Silk Films on the Growth Fujisato (3) Jason A. Inzana (1,2); Diana Olvera (1,2); Acellular Scaffold for Wound Regeneration Medicine, Wake Forest School of Medicine Behavior of Retinal Pigment Epithelial Cells Department of Integrated Life, Osaka Seikei Is In Vivo Recellularization of Acellular Seth Fuller (4); Olivia A. Graeve (4,5); Edward Lorenzo Pio Serino (1); Peter D. Iddon (1); (1); Institute of Advanced Biomedical So Jin Lee (1); Jaewon Yang (1); Jung Hwan College (1) Department of Biomedical Dermal Matrices Associated with Variables M. Schwarz (1,2,3); Stephen L. Kates (2,3); Michael J. Raxworthy (1) Engineering and Science, Tokyo Women’s Lee (1); Eun Young Kim (1); Jeong Eun Song Engineering, Osaka Institute of Technology in the ECM? Hani A. Awad (1,2,3) Neotherix Limited (1) Medical University (2) (1); Choun-Ki Joo (2); Dongwon Lee (1); (2) Major in Biomedical Engineering, Osaka Gabriella M. Dahlgren (1); Pearl M. Assan (1); Biomedical Engineering, University of Gilson Khang (1) Institute of Technology (3) Maryellen Sandor (1); Patrick G. De Deyne (1) Rochester (1); Center for Musculoskeletal Department of BIN Fusion Technology, LifeCell Corporation (1) Research, University of Rochester Medical Department of PolymerNano Science & Center (2); Orthopaedics, University of Technology and Polymer BIN Research Rochester Medical Center (3); Kazuo Inamori Center, Chonbuk National University, School of Engineering, Alfred University (4); Jeonju, Chonbuk, Korea (1); Department of Mechanical and Aerospace Engineering, Ophthalmology and Visual Science, College University of California, San Diego (5) of Medicine, The Catholic University (2)

32 33 POSTER SESSION II – TUESDAY, NOVEMBER 12, 2013 2:30 – 4:00 PM POSTER SESSION II – TUESDAY, NOVEMBER 12, 2013 2:30 – 4:00 PM

123 128 134 138 142 147 153 159 Tae Hyun Choi Xia Liu Jeong-Hoon Oh Joshua Farber Mike Modo Jason Rashkow Devon Headen Zhengsheng Zhang Regeneration of Peripheral Nerves by Self-Renewal and Differentiation Capacity Fabrication of Biomimetic Shaped Ceramic Pre-Operative Evaluation of Patients Use of MRI to Non-Invasively Guide ECM- Towards Nanobiomaterials for Stem Cell Microfluidic Gelation of Synthetic Cell-Laden Immunomodulatory Properties of Urine- Transplanted Sphere of Human Mesenchymal of Urine-Derived Stem Cells after Urine Ossicles and Evaluation of their Vibration Undergoing Knee Articular Cartilage Defect Gel Treatment of Stroke Lesions in a Rat Therapies in Regeneration Medicine: Microgels: Controlling Particle Size with Flow Derived Stem Cells Stem Cells Derived from Embryonic Stem Preservation for 24 Hours Performance using Finite Element Method Repair: MRI 3D Thickness Maps derived Model The Effects of Two Dimensional Carbon Rate Zhengsheng Zhang (1); Rongpei Wu (1,2); Cells Liu Xia; Ren Lang; Guihua Liu; Yingai Shi; Jeong-Hoon Oh (1); Jung-Seob Lee1 (2); from a Validated, Automated Segmentation Andre R. Massensini (1,3,5); Christopher J. Nanoparticles on the Viability and Devon M. Headen (1); Guillaume Aubry (2); Melisa Soland (1); Guihua Liu (1); Anthony Eun Ju Lee (1); Lianji Xu (2); Gi-Hwan Kim (1); Shantaram Bharadwaj; Anthony Atala; Dong-Woo Cho (2) Platform Medberry (1,2); Wen Ling (1,3); Stephen F Differentiation of Adipose Derived Stem Cells Hang Lu (3); Andrés J. García (4) Atala (1); Graca Almeida-Porada (1) and Soo Kyoung Kang (1); Sae-Won Lee (1); Sung- Yuanyuan Zhang Department of Otolaryngology-Head and Joshua M. Farber, MD; Eric Brandser, MD; Badylak (1,2,4); Michel Modo (1,2,3) Jason T Rashkow (1); Yahfi Talukdar (1); Woodruff School of Mechanical Engineering, Yuanyuan Zhang (1) Hye Park (3); Sukwha Kim (2); Tae Hyun Choi Wake Forest Institute for Regenerative Neck Surgery, The Catholic University of Saara Totterman, MD, PhD; Jose Tamez-Pena, University of Pittsburgh, McGowan Institute Gaurav Lalwani (1); Balaji Sitharaman (1) Georgia Institute of Technology (1); Petit Wake Forest Institute for Regenerative (2); Hyo-Soo Kim (1,4) Medicine, Wake Forest School of Medicine, Korea, College of Medicine, Korea (1); PhD; Bruce Holladay, MD; John Larkin, MD; for Regenerative Medicine (1); Department of Biomedical Engineering, Stony Brook Institute for Bioengineering and Bioscience, Medicine, Wake Forest School of Medicine, National Research Laboratory for Stem Cell Winston-Salem, North Carolina Department of Mechanical Engineering, Forest Heis, MD; Philip Smith Bioengineering (2); Department of Radiology University (1) Georgia Institute of Technology (2); School Winston-Salem, North Carolina (1); The First Niche and IRICT, Seoul National University Pohang University of Science and Technology, Clinical Applications, Qmetrics Technologies; (3); Department of Surgery, Pittsburgh, of Chemical and Biomolecular Engineering, Affiliated Hospital, Sun Yat-sen University, Hospital, Republic of Korea (1); Department 129 Korea (2) Division of Radiology, Radiology Associates Pennsylvania (4); Universidade Federal de 148 Georgia Institute of Technology (3) Guangzhou, China (2) of Plastic and Reconstructive Surgery, Institute Dawit Seifu of Northern Kentucky; Clinical Applications, Minas Gerais, Department of Physiology and Etai Sapoznik of Dermatologic Science, Seoul National Engineering a Multi-wall Vascular Construct IMAGING (CELL TRANSPLANTATION, Qmetrics Technologies; Imaging Science Biophysics, Belo Horizonte, Brazil (5) Fiber Based Imaging on Electrospun Scaffold 154 160 University College of Medicine, Republic of by Directly Processing Cells and Collagen TISSUE FUNCTION, REGENERATION) and Statistics, Tec de Monterrey; Orthopedic Etai Sapoznik (1,2); Guoguang Niu (1); Peng Mohammad Hossain Joshua Zimmermann Korea (2); Department of Pathology, Seoul Gels in Co-culture in Rotating Bioreactor Surgery, Commonwealth Orthopaedic 143 Lu (3); Tracy L. Criswell(1); Yong Xu (2,3); Recombinant Flagellin Enhances NK Cell Modulation of Mesenchymal Stem National University College of Medicine, Dawit G Seifu (1); Sébastien Meghezi (1); 135 Centers; Orthopedic Surgery, Commonwealth Aaron Mohs Shay Soker (1,2) Immunity against CMV Infection: a Clinical Cell Microenvironments to Enhance Republic of Korea (3); Molecular Medicine & Larry Unsworth (2); Kibret Mequanint (3); Alyssa Appel Orthopaedic Centers; Orthopedic Surgery, Near Infrared Labeling and Detection Wake Forest Institute for Regenerative Implication Immunomodulatory Paracrine Secretion Biopharmaceutical Sciences, Seoul National Diego Mantovani (1) Visualizing Hydrogels in Soft Tissue with Commonwealth Orthopaedic Centers of Enteric Nerve Cells: Tracking of Medicine, Wake Forest University (1); Virginia Mohammad S. Hossain (1); Edmund K. Joshua A. Zimmermann (1); Todd C. McDevitt University, Seoul, Republic of Korea (4) Laboratory for Biomaterials and X-rays without Contrast Agents Differentiating Neural Progenitor Cells and Tech-Wake Forest School of Biomedical Waller (1) (1,2) Bioengineering, Laval University, Québec Alyssa A. Appel (1,2); Jeffery C. Larson (1,2); 139 Tissue Innervation Engineering and Sciences (2); Department of Department of Hematology and Medical The Wallace H. Coulter Department of 124 City, Canada (1); Department of Chemical Alfred B. Garson III (3); Huifeng Guan (3); Zohreh Izadifar Aaron M. Mohs (1,2); Robert R. Gilmont (1); Electrical and Computer Engineering, Virginia Oncology, Division of Bone Marrow Biomedical Engineering, Georgia Institute Fiona Freeman and Materials Engineering, University of Bin Jiang (1,2); Zhong Zhong (4); Mark A. Lower Dose X-ray Imaging for Visualization of Christopher Booth (1); Lysette A. Mutkus (1); Technical Institute (3) Transplantation, Winship Cancer Institute, of Technology & Emory University (1); The Simulating the Biochemical and Mechanical Alberta, Edmonton, Canada (2); Department Anastasio (3); Emmanuel C. Opara (5); Eric Scaffolds Implanted in Cartilage Frank C. Marini (1); Khalil N. Bitar (1,2) Emory University (1) Parker H. Petit Institute for Bioengineering cues of Endochondral Ossification to Develop of Chemical and Biochemical Engineering, M. Brey (1,2) Zohreh Izadifar (1); L. Dean Chapman (1,2,3); Wake Forest Institute for Regenerative 149 and Bioscience, Georgia Institute of an Effective Bone Tissue Regeneration Strategy Western University, London, Canada (3) Biomedical Engineering, Illinois Institute of X.B. Daniel Chen (1,4) Medicine, Winston-Salem, North Carolina Maya Schnabel-Lubovsky 155 Technology (2) Fiona E. Freeman (1,2); Matthew G. Haugh Technology (1); Research Services, Edward Division of Biomedical Engineering, (1); Wake Forest - Virginia Tech School of Nano-Scale Cell-Matrix Interactions through Sunyoung Joo (1,2); Laoise M. McNamara (1,2) 130 Hines Jr. VA Hospital (2); Biomedical University of Saskatchewan (1); Department Biomedical Engineering and Sciences, Amorphous Hydrogel Polymeric Networks Myogenic differentiated Allogeneic MANUFACTURING TECHNOLOGIES Centre for Biomechanics Research (BMEC), Stefan Stich Engineering, Washington University in of Anatomy and Cell Biology, University of Winston Salem, North Carolina (2) Maya Schnabel-Lubovsky (1,2); Dror Seliktar Mesenchymal Stem Cells are Capable AND PLATFORMS Biomedical Engineering, NUI Galway, Characterization of Sngle Cell Derived St. Louis (3); National Synchrotron Light Saskatchewan (2); Biomedical Imaging and (1,3); Yeshayahu Talmon (2,3). of Modulating the Immune Response by Ireland (1); National Centre for Biomedical Cultures of Periosteal Progenitor Cells to Source, Brookhaven National Laboratory (4); Therapy (BMIT) Beamline, Canadian Light 144 Departments of Biomedical Regulatory T Cells 161 Engineering Sciences, NUI Galway, Ireland Ensure the Quality for Clinical Application Institute for Regenerative Medicine Center for Source (CLS) (3); Department of Mechanical Guoguang Niu Engineering,Technion-Israel Institute of Sunyoung Joo (1,2); Hyun Ju Lim (1); John Taby Ahsan (2) Stefan Stich (1); Alexander Loch (2); Michael Biomolecular Imaging Center for Diabetes Engineering, University of Saskatchewan (4) Fluorescent Imaging of Cells in Tissue Technology (1); Chemical Engineering, D. Jacksonv (1); Anthony Atala (1); James J. Hypoxia Effects on Pluripotent Stem Cell Sittinger (1); Jochen Ringe (1) Research, Wake Forest (5) Engineering Blood Vessels: the Impact of Technion-Israel Institute of Technology (2); Yoo (1,2) Differentiation is Modulated by the Physical 125 Tissue Engineering Laboratory & Berlin- 140 Cross-linking on Autofluorescence of the The Russell Berrie Nanotechnology Institute Wake Forest Institute for Regenerative Microenvironment Masanobu Horie Brandenburg Center for Regenerative 136 Shruti Kanakia Scaffold (RBNI), Technion-Israel Institute of Technology Medicine, Wake Forest School of Medicine Russell P. Wolfe (1); Taby Ahsan (1) Growth in Single Aggregates of Human Therapies (BCRT), Department of Alyssa Appel AA Novel MRI Contrast Agent to Assess Tissue Guoguang Niu (1); Etai Sapoznik (1,3); Peng (3) (1); Joint Institute for Regenerative Medicine, Biomedical Engineering, Tulane University (1) Induced Pluripotent Stem Cells Rheumatology and Clinical Immunology, Monitoring Tissue Development within Growth of Renal Transplant Lu (2); Tracy Criswell (1); Aaron M. Mohs Kyungpook National University Hospital (2) Masanobu Horie; Emilda Teresa Gomez; Eiji Charité - Universitätsmedizin Bioreactors without Exogenous Contrast Shruti Kanakia; Jimmy Toussaint; Sayan (1,3); Ge Wang (3); Sang-Jin Lee (1); Yong Xu 150 162 Nagamori; Masahiro Kino-oka Berlin, Germany (1); Department Alyssa A. Appel (1,2); Jeffery C. Larson (1,2); Mullick Chowdhary; Tanuf Tembulkar; (2); Shay Soker (1,3) John Walker 156 David Dean Department of Biotechnology, Graduate of Otorhinolaryngology, Charité - Alfred B. Garson III (3); Huifeng Guan (3); Stephen Lee; Kenneth Shroyer; William Wake Forest Institute for Regenerative Perfusion CT for Assessment of en bloc Hyung Keun Kim Resin Component Optimization for Green School of Engineering, Osaka University, Universitätsmedizin Berlin, Germany (2) Zhong Zhong (4); Bao-Ngoc Nguyen(5); John Moore; Balaji Sitharaman Medicine, Wake Forest Baptist Medical Implant Vascular Success Salidylideneamino-2-thiophenol Enhances Strength of Photocrosslinked Resorbable Suita, Osaka, Japan Fisher (5); Mark A. Anastasio (3); Eric M. Brey Department of Biomedical Engineering, Center,Medical Center Boulevard, Winston- John A. Walker (1,2); Marcello Pilia (2); ALP and Calcium Activity via MAPK Scaffolds Prepared by Continuous 131 (1,2) Stony Brook University, Stony Brook, New Salem, North Carolina (1); Bradley Thomas J. Walters (2); Jennifer McDaniel Signaling Pathway Stimulation during Digital Light Processing (cDLP) Additive 126 Qian Wan Biomedical Engineering, Illinois Institute of York; Department of Radiology, Stony Department of Electrical and Computer (2); Joseph C. Wenke (1,2); Christopher R. Osteogenesis Manufacturing Takahiro Iwamiya Functional Urothelial Differentiation of Technology (1); Research Services, Edward Brook University, Stony Brook, New York; Engineering (2); Virginia Tech-Wake Forest Rathbone (2) Hyung Keun Kim (1,2); Ji Hyun Kim (2); Dae David Dean (1); Eric Mott (1); Xinyi Luo (2); The Functional Evaluation of ES Cell-derived Urine-derived Stem Cells for Potential use in Hines Jr. VA Hospital (2); Biomedical Department of Pathology, Stony Brook University School of Biomedical Engineering Department of Radiology, University of Texas Sung Park (2); Kyung Soon Park (2); Jong Keun Martha O. Wang (3); Charlotte E. Vorwald (3); Cardiac Cell Sheet with Different Types of Urethral Tissue Repair Engineering, Washington University in University, Stony Brook, New York and Sciences, Virginia Technical Institute, Health Science Center at San Antonio (1); Seon (2); Eun Kyoo Song (2); Myung Ho Jeong Ali Siblani (4); John P. Fisher (3) Fibroblasts Qian Wan; Guihua Liu; Shantaram St. Louis (3); National Synchrotron Light Blacksburg, Virginia (3) Extremity Trauma & Regenerative Medicine, (1); Taek Rim Yoon (1,2) Plastic Surgery, The Ohio State University Takahiro Iwamiya; Katsuhisa Matsuura; Bharadwaj; Anthony Atala; Yuanyuan Zhang Source, Brookhaven National Laboratory (4); 141 United States Army Institute of Surgical Heart Research Center of Chonnam National (1); Neurological Surgery, Case Western Tatsuya Shimizu; Noriko Yasuda; Teruo Wake Forest Institute for Regenerative Department of Bioengineering, University of Hyung Keun Kim 145 Research (2) University Hospital, Gwangju, Korea (1); Reserve University (2); Fischell Department of Okano Medicine, Wake Forest School of Medicine, Maryland (5) Bone Forming Peptide1 (BFP1) Enhances ALP Karl Nobert Joint Center of Chonnam National University Bioengineering, University of Maryland (3); Institute of Advanced Biomedical Engineering Winston-Salem, North Carolina Expression and Osteogenic Differentiation The Regulation of Regenerative Medicine in 151 Hwasun Hospital, Jeonnam, Korea (2) EnvisionTEC, Inc. (4) and Science, Tokyo Women’s Medical 137 via Smad and Erk Signal Protein Stimulation the United States Sean White University 132 Ian Copland during Osteogenesis Karl M. Nobert Longitudinal Quantification of Vascular 157 163 Lijun Zhang Microfluidic Modeling of MSC Homing/ Hyung Keun Kim (1,2); Ji Hyun Kim (2); Dae Squire Sanders (United States) LLP, Density and Function in Implantable Porcine Christina Ross Timothy Ganey 127 Immunoregulatory Property of Long-term Engraftment Recapitulates In Vivo Engraftment Sung Park( 2); Kyung Soon Park (2); Jong Keun Washington, District of Columbia Acellular Dermal Matrix Effect of Pulsed Electromagnetic Field on Surface Characterization of Etched PEEK Jaehyun Kim Cultured Human Mesenchymal Stem Cell Defects Associated with Cryopreservation Seon(2); Eun Kyoo Song (2); Myung Ho Jeong Sean M. White (1); Chelsea Pittman (1); Inflammatory Pathway Markers in RAW Implants Downregulation of Metabolic Activity Sheets Raghavan Chinnadurai (1); Yumiko Sakurai (1); Taek Rim Yoon (1,2) 146 Tamim Diab (2); Patrick G. De Deyne (2); 264.7 Murine Macrophages Timothy Ganey (1); Lisa Detter-Hoskin (2); Increases Cell Survival under Hypoxic Lijun Zhang (1,2); Lei Chen( 2); Qi Xing (1); (2,3); Wilbur Lam (2,3); Jacques Galipeau Heart Research Center of Chonnam National Ryan Porter Steven C. George (1); Bernard Choi (1) Christina L. Ross (1,2); Benjamin S. Harrison Frank E. Livingston (3) Conditions Mitchell Tahtinen (1); Feng Zhao (1) (1,2); Ian Copland (1) University Hospital, Gwangju, Korea (1); Refinement of a Rat Model for Studying Biomedical Engineering, University of (2) Department of Orthopaedic Surgery, Atlanta Jaehyun Kim; Karl-Erik Andersson; Sang Jin BioMedical Engineering, Michigan Department of Hematology and Oncology, Joint Center of Chonnam National University Progenitor Cell Contribution to California, Irvine (1); LifeCell Corporation (2) Akamai University, Department of Energy Medical Center (1); Materials Analysis, Lee;John D. Jackson; James Yoo; Anthony Technological University, Houghton, Winship Cancer Institute, (1); Department Hwasun Hospital, Jeonnam, Korea (2) Osteochondral Defect Repair Medicine, Hilo, Hawaii (1); Wake Forest Georgia Institute of Technology Research Atala Michigan (1); Department of Burns, First of Pediatrics, Emory University (2); Wallace Ryan M. Porter (1); Alfredo M. Scheu (1); IMMUNOMODULATION Institute for Regenerative Medicine, Wake Institute (2); Aerospace Corporation (3) Wake Forest Institute for Regenerative Affiliated Hospital of Sun Yat-sen University, H. Coulter Department of Biomedical Fangjun Liu (1); James W. Wells (1,2); Forest University School of Medicine, Medicine, Wake Forest School of Medicine, Guangzhou, China (2) Engineering, and Georgia Institute of Elisabeth Ferreira (1); Christopher H. Evans (1) 152 Winston-Salem, North Carolina (2) 164 Winston-Salem, North Carolina Technology (3) Orthopaedic Surgery, Beth Israel Deaconess Gustavo Garlet Timothy Ganey COMPUTATIONAL MODELING Medical Center / Harvard Medical School DAMPS/CD14/MYD88 Axis In Host Response 158 Advanced Laser Technology for Developing (1); Epithelial Cancer Division, University of To Biomaterial Grafting: Understanding Kara Spiller Biomimetic Implants in a Sheep Model for 133 Queensland Diamantina Institute (2) and Interfering With The Inflammatory Vascularization of Tissue Engineering Intervertebral Body Fusion Pinar Huri Immune Response to Enhance Healing and Scaffolds through Modulation of Macrophage Frank E. Livingston (1); Patrick Colahan (2); Modeling In Vitro Adipose-Derived Stem Cell Regeneration Processes Outcome Behavior Ted Broom (2); Timothy Ganey (3) Myogenesis in Response to Biophysical Cues Elcia MV Silveira (1); Ana C Araujo-Pires (1); Kara L. Spiller (1); Rachel Anfang (1); Krista J. Aerospace Corporation (1); Large Animal Pinar Y. Huri (1); Douglas J. DiGirolamo (2); Carlos E Repeke (1); Ana Paula Campanelli Spiller (2); Johnathan Ng (1); Gordana Vunjak- Surgery, College of Veterinary Medicine, Alexander A. Spector (1); Warren L. Grayson (1); Joao S Silva (1); Ana Paula Favaro Novakovic (1) University of Florida (2); Department of (1) Trombone (2); Gustavo Pompermaier Biomedical Engineering, Columbia University Orthopaedic Surgery, Atlanta Medical Center Biomedical Engineering, Johns Hopkins Garlet(1) (1); Pathology, Columbia University (2) (3) University (1); Orthopaedic Surgery, Johns FOB/USP, Sao Paulo University, Bauru, SP, Hopkins University, Baltimore, Maryland (2) Brasil (1); Universidade Sagrado Coração Bauru, SP, Brasil (2)

34 35 POSTER SESSION II – TUESDAY, NOVEMBER 12, 2013 2:30 – 4:00 PM POSTER SESSION II – TUESDAY, NOVEMBER 12, 2013 2:30 – 4:00 PM

165 172 177 182 188 193 197 203 Anastasia Georgiou Sua Park Nian Shen Wei Chen Aleksander Skardal Yang Liu Zhan Wang Rebecca Howie Chemical Osteoinduction with Simvastatin Preparation of NaOH-treated Surface on Development of a Bioreactor System for 2D Skeletal Myogenic Differentiation of Urine- Delivery of Amniotic Fluid-Derived Stem A Self-assembling Peptide Reduces Methods to Improve Expansion and Bisphosphonate Release from Bone Following and Generation of 3D Mineralised Cellular Three-dimensional (3D) Polymeric Scaffold and 3D Elastogenesis Derived Stem Cells and Angiogenesis Using Cells in a Heparin-Functionalized Hyaluronic Glial Scarring, Attenuates Post-traumatic Engraftment of Myogenic Progenitor Cells for Cadmium Administration Constructs In a Perfusion Bioreactor Fabricated by Rapid Prototyping Nian Shen (1,2); Svenja Hinderer (1,3); Jan Microbeads Loaded with Growth Factors Acid Hydrogel Gel Accelerates Skin Inflammation and Promotes Neurological Muscle Regeneration R. Nicole Howie (1); Tara Brown (2); Loan Anastasia Georgiou (1); Eleftherios Tsiridis (2); Sua Park (1); Junhee Lee (1); Wandoo Kim (1) Hansmann (2); Katja Schenke-Layland (1,2) for Potential Treatment of Stress Urinary Regeneration Recovery following Spinal Cord Injury Zhan Wang (1); Dan Cheung (2); Yu Zhou Tran (2); J. Nathan Raley (2); Maryka Manolis Heliotis (3); Athanasios Mantalaris (1) Nano-Mechanical Systems Research Department of Cell and Tissue Engineering, Incontinence Aleksander Skardal (1); Sean Murphy (1); Yang Liu (1); Hui Ye (1); Kajana (1); Changjie Han (1); Tracy Criswell (1); Shay Bhattacharyya (3); James Borke (4); Biological Systems Engineering Laboratory, Division, Korea Institute of Machinery & Fraunhofer IGB, Stuttgart, Germany Wei Chen; Guihua Liu; Rajesh A. Pareta; David Mack (2); Shay Soker (1) Satkunendrarajah (1); Gordon S. Yao (1); Yves Soker (1,3) Mohammed Elsalanty (1) Department of Chemical Engineering, Materials (1) (1); University Women’s Hospital Rongpei Wu; Yingai Shi; Xiaobo Zhou; Wake Forest Institute for Regenerative Bayon (2); Michael G. Fehlings (1,3,4) Wake Forest Institute for Regenerative Oral Biology, Georgia Regents University (1); Imperial College London (1); Faculty of Tübingen and Inter-University Centre for Anthony Atala; Emmanuel C. Opara and Medicine, Wake Forest School of Medicine Department of Genetics and Development, Medicine (1), Oregon State University, School College of Dental Medicine, Georgia Regents Medicine, Imperial College London Medical 173 Medical Technology Stuttgart-Tübingen Yuanyuan Zhang (1); Department of Rehabilitation Medicine, Toronto Western Research Institute and Spinal of Chemical, Biological, and Environmental University (2) Orthopedics, Georgia Regents School (2); Northwick Park Hospital, Joshua Price (IZST), Eberhard Karls University, Wake Forest Institute for Regenerative University of Washington (2) Program, Krembil Neuroscience Centre, Engineering (2) University (3); College of Dental Medicine, Maxillofacial Unit, London, United Kingdom Cyclic Hydrostatic Pressure Stimulates Tübingen, Germany (2); Institut für Medicine, Wake Forest School of Medicine, University Health Network, Toronto, Ontario, Western University of Health Sciences (4) (3) Enhanced Bone Formation in hMSC-seeded Grenzflächenverfahrenstechnik und Winston-Salem, North Carolina 189 Canada (1); Covidien - Sofradim Production, PRECLINICAL ANIMAL MODELS Hydrogels and Organotypic Skeletal Cultures. Plasmatechnologie (IGVP), University of Ni Su Trevoux, France (2); Department of Surgery, 204 166 Joshua Price (1); James R. Henstock (1); Stuttgart, Germany (3) 183 Nano-fibrous Scaffolds Potentiate the Anti- University of Toronto, Ontario, Canada (3); 198 Dietmar Hutmacher Jonathan Gerstenhaber Yvonne Reinwald (1); Alicia J. El Haj (1) Brandon Hanna inflammatory and Angiogenic Paracrine Institute of Medical Sciences, University of Jonathan Cheetham A Novel Spatiotemporal Delivery System Delta-Style Robot for Electrospinning from Institute for Science and Technology in 178 Role of HIF-1 in Transducing the Effects of Function of Adipose-derived Stem Cells Toronto, Ontario, Canada (4) Nerve Specific Extracellular Matrix Hydrogel of rhBMP-2 for the Regeneration of Critical Rapid Prototyped Parts Medicine, Keele University, United Kingdom Mousa Younesi Ischemic Preconditioning of Mesenchymal Ni Su (1); Yi Zhong (1); Kai Wang (1); Ying for Laryngeal Nerve Repair Sized Bone Defects in an Ovine Large Animal Jonathan A Gerstenhaber (1); Patrick Fabrication of 3D-Complex Solid Forms by Stem Cells for Bone Repair Luo (1,2); 194 Jonathan Cheetham (1); Travis Prest (2); Model Thompson (2); Yah-el Har-el (1); Peter I. Lelkes 174 Electrochemical Compaction of Collagen Brandon Hanna (1); Suchit Sahai (1); Matt Department of Biomedical Engineering, Vasudevan Mahalingam Matthew Martin (1); Samuel LoPresti (2); Jan Henkel (1); Arne Berner (1,2); Siamak (1) Vanessa Ragaglia Rich Solutions Skiles (1); James Blanchette College of Engineering, Peking University, Allogenic vs Autologous Derived Cell Sources Manuel Martine (1); Bryan N. Brown (2) Saifzadeh (1); Ian C. Dickinson (4); Mia Department of Bioengineering, Temple GMP Manufacture of a Clinical-Grade, Mousa Younesi (1); Vipuil Kishore (1); Biomedical Engineering, University of South Beijing, China (1); National Engineering for use in Engineered Bone-Ligament-Bone Cornell University, Ithaca, New York Woodruff (1), Robert E. Guldberg (3); Michael University (1); School of Biomedical Off-the-Shelf, Adult Bone Marrow-Derived Anowarul Islam (1); Ozan Akkus (1, 2, 3) Carolina (1) Laboratory, Biomedical Engineering, Georgia for Sheep ACL Repair (1); University of Pittsburgh, Pittsburgh, A. Schuetz (1,4); Dietmar W. Hutmacher (1,3) Engineering Science and Health Systems, Stromal Cell Product Department of Mechanical and Aerospace Institute of Technology (1); Biomedical Vasudevan Mahalingam (1); Michael J. Pennsylvania (2) Institute of Health and Biomedical Drexel University (2) Vanessa Ragaglia; Priya R. Baraniak Engineering, Case Western Reserve University 184 engineering, Emory University (2) Smietana (2); Tyler J. Olsen (3); Edward M. Innovation, Queensland University of Research Operation, Garnet BioTherapeutics, (1); Department of Biomedical Engineering, Jennifer Lei Wojtys (4); Deneen M. Wellik (5,6); Ellen M. 199 Technology, Brisbane, Australia (1); 167 Inc. Case Western Reserve University (2); Biomolecule Delivery from MSC Spheroid 190 Arruda (3,7); Lisa M. Larkin (1,2) Tracy Criswell Department of Trauma Surgery, Regensburg Stephen Goldman Department of Orthopedic Surgery, Case Surfaces for Modulation of Local Tissue Jenna Wilson Molecular & Integrative Physiology, Cell Therapy for the Functional Improvement University Medical Center, Germany (2); Shear Stress Modulates Expression of 175 School of Medicine, Case Western Reserve Environment Alginate Microencapsulation Modulates the University of Michigan (1); Biomedical of Injured Skeletal Muscle in Older Rats George W. Woodruff School of Mechanical Collagen mRNAs in Bone Marrow Derived Rodrigo Rezende University (3) Jennifer Lei (1); Tobias Miller (2); Johnna S. Phenotype and Secretion of Embryonic Stem Engineering, University of Michigan (2); Tracy Criswell (1); Yu Zhou (1); Daniel Lovell Engineering, Georgia Institute of Technology Mesenchymal Stem Cells Dual Scale Scaffolds via Fusion Deposition Temenoff (2,3) Cell Aggregates Mechanical Engineering, University of (1); Maigen Bethea (1); Shay Soker (1) (3); Department of Orthopaedic Surgery, Stephen M. Goldman (1,2); Gilda A. Modeling and Electrospinning for Tissue 179 George W. Woodruff School of Mechanical Jenna L. Wilson (1); Mohamad Ali T. Najia (1); Michigan (3); Orthopaedic Surgery, University Wake Forest Institute for Regenerative Princess Alexandra Hospital and the Wesley Barabino (1,3) Engineering Applications Long Zhao Engineering, Georgia Institute of Technology Rabbia Saeed (1); Todd C. McDevitt (1,2) of Michigan (4); Internal Medicine, University Medicine, Wake Forest University (1) Medical Centre, Brisbane (4) Interdisciplinary Bioengineering Graduate M.A. Sabino (1,2); R. Rezende (1); M. Loaiza Controlled Micro-droplet Deposition and (1); Wallace H. Coulter Department of The Wallace H. Coulter Department of of Michigan (5); Cell & Developmental Program, Georgia Institute of Technology (2,3); J. Salazar (2), Z. Fermin (1,2); F.D. Application for Cell Printing Biomedical Engineering, Georgia Institute of Biomedical Engineering, Georgia Institute of Biology, University of Michigan (6); 200 205 (1); G.W. Woodruff School of Mechanical Pereira (1); P. Inforcatti (1); V. Mironov (1); J.L. Long Zhao (1); Chang K. Yan (2); Feng Lin (3); Technology and Emory University (2); Petit Technology, Atlanta, Georgia (1); The Parker Macromolecular Science & Engineering, Celeste Finnerty Vivek Raut Engineering, Georgia Institute of Technology Da Silva (1) Wei Sun (4) Institute for Bioengineering and Bioscience, H. Petit Institute for Bioengineering and University of Michigan (7) Characterization of Adipose Derived Stem Tethered Epidermal Growth Factor Delivery (2); Wallace H. Coulter Department of Division of 3D Technologies, Center for Biomanufacturing Engineering Research Georgia Institute of Technology (3) Bioscience, Georgia Institute of Technology, Cells (ASCs) Following Burn Injury for the Repair of Large Segmental Bone Biomedical Engineering, Georgia Institute of Information Technology Renato Archer, Institute, Department of Mechanical Atlanta, Georgia (2) 195 Anesh Prasai (1); Amina El Ayadi (2, 5); David Defects Technology (3) Campinas, São Paulo, Brazil (1); Department Engineering, Tsinghua University (1); 185 Michael Smietana N. Herndon (2,5); Celeste C. Finnerty (2,3,4,5) Vivek P. Raut (1); Jaime J. Rivera (2); Viviane of Chemistry, Grupo B5IDA, Universidad Department of Mechanical Engineering, The Aaron Maki POLYTRAUMA MODELS OF REPAIR/ Utilization of 3-D Tissue Engineered Cell Biology Graduate Program, University Luangphakdy (1); Phil Zaveri (1); Luis M. 168 Simón Bolívar, Caracas, Venezuela (2); College of New Jersey (2); Department of Culturing Porcine Adipose-Derived Stem REGENERATION Constructs to Improve Tendon-Bone Healing of Texas Medical Branch (1); Department of Alvarez (2); Linda A. Stockdale (2); Cynthia A. Revital Goldshmid Department of Chemistry, Universidad Mechanical Engineering, Drexel University Cells with Platelet-Rich Plasma Following Rotator Cuff Repair Surgery, University of Texas Medical Branch Boehm (1); Alan Wells (3); Linda G. Griffith Microgel Suspension Culture System for Nacional Exp. Francisco de Miranda. Pto. (3) Aaron J. Maki (1); Rathnaweera A.C. Rabel 191 Michael J. Smietana (1); Ellen M. Arruda (2); Institute for Translational Sciences, (2); George F. Muschler (1) hMSCs Bioprocessing Fijo, Falcón, Venezuela (3) (2); Ekta Khetan (3) Anna C.M. Ercolin (2); Mariana Cerqueira (1,2,3); Asheesh Bedi (4); Lisa M. Larkin (1,5) University of Texas Medical Branch (3); Sealy Biomedical Engineering, Cleveland Clinic Revital Goldshmid and Dror Seliktar Kelly S. Roballo (2); Jamey J. Cooper (4); Gellan Gum-Hyaluronic Acid Spongy- Biomedical Engineering, University of Center for Molecular Medicine, University of (1); Biological and Mechanical Engineering, Faculty of Biotechnology, Technion - Israel 176 PARACRINE/TROPHIC DELIVERY Matthew B. Wheeler (1,2) like Hydrogels and Adipose Tissue- Michigan (1); Mechanical Engineering, Texas Medical Branch (4); Shriners Hospital Massachusetts Institute of Technology (2); Institute of Technology, Haifa, Israel Rodrigo Rezende Bioengineering, University of Illinois (1); Derived Lineages Synergise Towards Skin University of Michigan (2); Macromolecular for Children (5) Department of Pathology, University of Scalable Biofabrication of Chondrospheres 180 Animal Sciences, University of Illinois (2); Regeneration Science and Engineering , University of Pittsburgh (3) 169 from Human Adipose Stem Cells Isolated by Ashley Allen Birla Institute of Technology, Hyderabad, M. T. Cerqueira; L. P. da Silva; T. C. Santos; Michigan (3); Orthopedic Surgery, University 201 Wada Masanori Mechanical Dissociation: a Comparison with Pre-Cultured vs. Syringe-Injected Hydrogels India (3); Molecular and Cellular Biology, R. P. Pirraco; V. M. Correlo; A. P. Marques; of Michigan (4); Molecular & Integrative Joseph Frank 206 The Development of Small Scale Bioreactor Human Cartilage-derived Progenitors Cells for In Vivo Stem Cell Delivery University of Illinois (4) R. L. Reis Physiology, University of Michigan (5) Pulse Focused Ultrasound (pFUS) Exposures Kiyoko Takemiya System for Human Induced Pluripotent Stem Karina R. Silva (1); Vladimir Mironov (2); Ashley B. Allen (1); Ian B. Copland (2); Hazel 3B’s Research Group - Biomaterials, in Muscle Causes Biphasic Molecular Therapeutic use of Encapsulated Genetically Cell Culture Wada Masanori (1); Matsuura Rodrigo A. Rezende (2); Jorge V.L. da Silva (2); Y. Stevens (3); Robert E. Guldberg (1,3) 186 Biodegradables and Biomimetics, University 196 Changes Resulting in Enhanced Homing of Engineered Mesenchymal Stem Cells for Katsuhisa (2); Ishikawa Yoichi (1); Shimizu Mellanie P. Stuart (1); João V. Belizário (1,4); Bioengineering, Georgia Institute of Ina Sarel of Minho, Headquarters of the European Joshua Tam Stem Cells: Implications for Cell Therapy Vascular Regeneration Tatsuya (2); Okano Teruo (2) Paulo E. Leite (1); Radovan Borojevic (3); José Technology (1); School of Medicine, Emory A Peripheral Blood-derived Cellular Institute of Excellence on Tissue Engineering In Vivo Reconstitution of Epidermal and Pamela A. Tebebi (1); Scott R. Burks (2); Ben Kiyoko Takemiya (1); Jane S. Titterington (1); R and D Section, Able Corporation, Tokyo, Mauro Granjeiro (1); Leandra Baptista (1,4) University (2); Mechanical Engineering, Population can be Differentiated into Neural and Regenerative Medicine, Guimarães, Dermal Skin Structures from Microscopic A. Nguyen (2); Saejeong J. Kim (2); Priyanka Giji Joseph (1); Daiana Weiss (1); Alicia N. Japan (1); Institute of Advanced Biomedical Division of Bioengineering, National Institute Georgia Institute of Technology (3); like Progenitor Cells Portugal, ICVS/3B’s - PT Government Skin Tissue Columns Venketesh (2); Joseph A. Frank (2) Lyle (1); Christa Caesar (1); Susan A. Safely Engineering and Science, Tokyo Women’s of Metrology, Quality and Technology Ina Sarel (1); Valentin Fulga (1) Associate Laboratory, Braga/Guimarães, Joshua Tam (1); Ying Wang (1); William A. Biomedical Engineering, The Catholic (2); Collin Weber (2); Ian B. Copland (3); Medical University, Tokyo, Japan (2) (Inmetro), Duque de Caxias, RJ, Brazil (1); 181 Research and Development, Hemostemix (1) Portugal Farinelli(1); R. Rox Anderson (1) University of America, Washington, District Jacques Galipeau (3,4); W. Robert Taylor Division of 3D Technologies, Center for Archana Boopathy Wellman Center for Photomedicine, of Columbia (1); Radiology and Imaging (1,5,6) 170 Information Technology Renato Archer, Hydrogel Stiffness Dependent Notch1 187 192 Massachusetts General Hospital, Harvard Sciences, National Institutes of Health, Division of Cardiology, Emory University Brian Nankervis Campinas, SP, Brazil (2); Excellion laboratory, Activation Regulates Cardiogenic Gene Claire Segar Tracy Criswell Medical School, Boston, Massachusetts (1) Bethesda, Maryland (2) School of Medicine (1); Department Shear Stress Conditions in the Quantum Cell Petrópolis, RJ, Brazil (3); Federal University of Expression in Rat Cardiac Progenitor Cells Harnessing Macrophage-Derived Paracrine Age and Gender Dependent Differences of Surgery, Emory University School of Expansion System Rio de Janeiro/Xerém, Duque de Caxias, RJ, Archana V. Boopathy (1); Pao Lin Che (1); Signaling to Modulate Hematopoietic Stem in Skeletal Muscle Regeneration after 202 Medicine (2); Department of Hematology Brian Nankervis (1); Kristina Fuerst (1); Khoa Brazil (4) Vince F. Fiore (1); Milton E. Brown (1); Yoshie Cells Compression Injury in Rats Amalia Gallegos-Cardenas and Medical Oncology, Emory University Vu (1) Narui (2); Khalid Salaita (2); Thomas H. Claire Segar (1); Molly Ogle (1); Edward Tracy Criswell (1); Yu Zhou (1); Daniel Lovell Robust Generation of Neural Stem Cells School of Medicine (3); Department of Terumo BCT (1) Barker (1); Michael E. Davis (1) Botchwey (1) (1); Maigen Bethea (1); Shay Soker (1) from Pig Induced Pluripotent Stem Cells for Pediatrics and Medicine, Hematology Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Wake Forest Institute for Regenerative Translational Neural Regenerative Medicine and Medical Oncology, Emory University 171 Biomedical Engineering at Emory University Technology and Emory University (1) Medicine, Wake Forest University (1) Amalia Gallegos-Cardenas(1-3); Kai Wang School of Medicine (4); Cardiology Division, Se Woong Park and Georgia Institute of Technology, Atlanta, (2); Erin T. Jordan (1,2); Rachel West (1,2); Atlanta Veterans Affairs Medical Center (5); Combination of Superhydrophilc Surface and Georgia (1); Department of Chemistry, Emory Franklin D. West (1,2); Jeong-Yeh Yang (1,2) Department of Biomedical Engineering, Chemically Bindable Surface for Enhacing University, Atlanta, Georgia (2) and Steven L. Stice (1,2) Emory University School of Medicine and Bone Differentiation Department of Animal and Dairy Science, Georgia Institute of Technology (6) Se Woong Park (1); Bo Ra Lee (2); Sung Gap the University of Georgia (1); Regenerative Im (2); Il Keun Kwon( 1) Bioscience Center, the University of Georgia, School of Dentistry, Kyung Hee University (1); Athens, Georgia (2); Department of Animal Department of Chemical and Biomolecular Production, National Agrarian University La Engineering, Korea Advanced Institute of Molina, Lima, (3) Science and Technology (2)

36 37 POSTER SESSION II – TUESDAY, NOVEMBER 12, 2013 2:30 – 4:00 PM POSTER SESSION II – TUESDAY, NOVEMBER 12, 2013 2:30 – 4:00 PM

207 211 215 222 REPROGRAMMING CELLS FOR TUMOR ENVIRONMENTS & CANCER 238 243 Laure Thibaudeau Roger De Filippo Samir Hasan Young-Doug Sohn REGENERATION BIOLOGY (LESSONS LEARNED) Vincent Siu Stephen Cronk Humanized Xenograft Model of Breast Protective Effect of Human Amniotic Fluid Stem Cell Concentration in Pediatric Adipose Enhanced Wound Repair by Novel The Effects of Various Fruit Extracts, Collagen, Adipose-derived Stem Cells from Healthy and Cancer Metastasis to Bone Stem Cells in Acute Tubular Necrosis Tissue Circulating Human Lymphatic Endothelial 227 232 and Fibronectin on the Proliferation and Diabetic Mice have Differential Effects on the Laure C. Thibaudeau (1); Boris M. Holzapfel Laura Perin (1,2,3,4,6,7); Sargis Sedrakyan Sheshashree Seshadri (1); Shaye Walston Progenitor Cells through Lymphatic James Dixon Luis Alonzo Migration of the Rhabdomyosarcoma-derived Retinal Microvasculature (1); Brett Hollier (1); Carl A. Power (2); Anna (1,2,3,4,6,7); Stefano Da Sacco (1,2,3,4,6,7); (1); Loretta Reyes (1); Ifeanyi Mbadugha (1); Neovascularization Switching Alginate/Collagen Hydrogels A 3D In Vitro Tumor Microenvironment with (RD) Cell Line Stephen M. Cronk (1); Thomas A. Mendel (2); V. Taubenberger (3); Dietmar W. Hutmacher Gianni Carraro (2,3,6,7); Liron Shiri Kevin Hopkins (2); Samir Hasan (3); Joan Young-Doug Sohn (1); Woan-Sang Kim (1); Tailored for Human Pluripotent Stem Cell Perfused Capillaries Vincent Siu (1); Stephanie DeSanti (1); Victor Ethan L. Nyberg (1); Anthony R. Sheets (3); (1) (1,2,3,4,6,7); Kevin Lemley (2,3,5,6,7); and Nichols (3) Do Hyun Park (1); and Young-sup Yoon (1) Self-renewal and Differentiation Luis Alonzo (1,2); Monica Moya (1,2); Marian Mikhaltsevich (1); Danny Tran (1); Melissa Anthony C. Bruce (1); Ira M. Herman (3); Paul Institute of Health and Biomedical Roger De Filippo (1,2,3,4,6,7) Pediatrics, Driscoll Children’s Hospital Divisions of Cardiology, School of Medicine, James E. Dixon (1); Catherine Rogers (1); Waterman (3,4); Chris Hughes (1,2,5); Steven McCoy (1); Bill Tawil (1) A. Yates (2); Shayn M. Peirce (1) Innovation, Queensland University of GOFARR Laboratory for Organ Regenerative (1); Plastic Surgery, Driscoll Children’s Emory University (1) Disheet A. Shah (1); Stephen Hall (2); Chris George (1,2,6) Department of Biotechnology and Biomedical Engineering, University of Virginia Technology (1); Biological Resource Imaging Research and Cell Therapeutics (1); Saban Hospital (2); Tissue Engineering and Organ Denning (3); Kevin M. Shakesheff (1) Biomedical Engineering, University of Bioinformatics, California State University, (1); Ophthalmology, University of Virginia Laboratory, University of New South Research Institute (2) ; Children’s Hospital Regeneration University of Texas Medical 223 Wolfson Centre for Stem Cells, Tissue California Irvine (1); Edwards Lifesciences Channel Islands (1) (2); Molecular Physiology and Pharmacology, Wales (2); BIOTEChnologisches Zentrum, Los Angeles (3); Division of Urology (4); Branch (3) Jane Titterington Engineering, and Modelling (STEM), Centre Center for Advanced Cardiovascular Tufts University (3) Technische Universität Dresden(3) Division of Nephrology (5); Keck School Encapsulation of Mesenchymal Stem Cells of Biomolecular Sciences, School of Technology (2); Microbiology and Molecular 239 of Medicine (6); University of Southern 216 to Improve Stem Cell Therapy Following Pharmacy (1); School of Clinical Science (3), Genetics, University of California Irvine (3); Laure Thibaudeau 244 208 California (7) Jinah Jang Myocardial Infarction in Rats Medical Engineering Unit (2), University of Cancer Research Institute Research Centers Investigating the Role of β1 Integrin in Breast Caitlin Czajka Thomas Walters Application of Decellularized ECM as a Bio Jane S. Titterington (1); Rebecca Levit (1); Nottingham, Nottingham, United Kingdom and Institutes, University of California, Irvine Cancer Bone Metastasis Using In Vitro and In Scaffold-free, Self-assembled, Vascularized Chronic Activity Improves Skeletal Muscle 212 Ink of 3D Cell Printing for Site Appropriate Giji Joseph (1); Kiyoko Takemiya (1); Milton (4); Molecular Biology and Biochemistry, Vivo Tissue Engineered Bone Models Tissue Constructs Tissue Functional Recovery after Volumetric Roger De Filippo Tissue Formation Brown (1); Devon Headen (2); Susan Safley 228 University of California, Irvine (5); Chemical Laure C. Thibaudeau (1); Anna V. Caitlin A. Czajka (1); Christopher J. Drake (1) Muscle Loss Amniotic Fluid Renal Progenitors and renal Jinah Jang (1); Tae-Ha Song (2); Min-Joo Kim (3); Collin J. Weber (3); Michael E. Davis Jochen Ringe Engineering and Material Science, University Taubenberger (2); Boris M. Holzapfel (1); Regenerative Medicine & Cell Biology, Thomas J. Walters (1); Koyal Garg (1); Extracellular Matrix: A New Approach for (1); Sung Won Kim (3); Dong-Woo Cho (2) (1,2); Andrés J. García (2); W. Robert Taylor Differentiation, Dedifferentiation and of California, Irvine (6) Dietmar W. Hutmacher (1) Medical University of South Carolina (1) Benjamin T. Corona (1) Kidney Regeneration Integrative Biosciences and Biotechnology, (1,2,4) Transdifferentiation Potential and Institute of Health and Biomedical Extremity Trauma and Regenerative Ilenia Zanusso (1,2,3,4,6,7); Stefano Da Pohang University of Science and Division of Cardiology, Emory University Mechanisms of Human MSC 233 Innovation, Queensland University of 245 Medicine; United States Army Institute of Sacco (1,2,3,4,6,7); Astgik Petrosyan Technology (1); Mechanical Engineering, (1); Department of Biomedical Engineering, Jochen Ringe (1); Mujib Ullah (1); Michael Boris Holzapfel Technology (1); BIOTEChnologisches Ruby Dewi Surgical Research (1) (1,2,3,4,6,7); Maria Teresa Conconi Pohang University of Science and Georgia Institute of Technology (2), Sittinger (1) Humanized Animal Models of Prostate Zentrum, Technische Universität Dresden (2) Chemotaxis of Human Induced Pluripotent (1,2,3,4,6,7); Kevin Lemley (2,3,5,6,7) ; Technology (2); Otolaryngology-Head and Department of Surgery, Emory University Tissue Engineering Laboratory & Berlin- Cancer Bone Metastasis - a New Method to Stem Cell-Derived Endothelial Cells REJUVENATING TISSUE/ORGAN Laura Perin (1,2,3,4,6,7); Roger De Filippo Neck Surgery, The Catholic University of (3); Division of Cardiology, Atlanta Veterans Brandenburg Center for Regenerative Investigate Species-specific Mechanisms of Ngan F. Huang (1,2,3); Ruby E. Dewi (4); FUNCTION (1,2,3,4,6,7) Korea (3) Administration Medical Center (4) Therapies, Department of Rheumatology Cancer Cell Osteotropism Janet Okogbaa (1); Jerry C. Lee (1); Abdul J. GOFARR Laboratory for Organ Regenerative and Clinical Immunology, Charité-University Boris Michael Holzapfel (1); Laure VASCULARIZATION Rufaihah (1); Sarah C. Heilshorn (4); John P. 209 Research and Cell Therapeutics (1); Saban 217 224 Medicine Berlin, Berlin, Germany (1) Thibaudeau (1); Pamela Russell (2); Dietmar Cooke (1,2). Sunitha Chandran Research Institute (2); Children’s Hospital Los Han-Tsung Liao Jason Wertheim Werner Hutmacher (1); 240 Division of Cardiovascular Medicine, Improved Fracture Healing in Rat Angeles (3), Division of Urology (4); Division The Effect of Bone-mimetic Environment on Changing Times in Solid Organ 229 Institute of Health and Biomedical Eren Raif Ayata Stanford University (1); Stanford Osteoporotic Model Using Mesencgymal of Nephrology (5); Keck School of Medicine Osteogenic Potential of Bone Barrow and Transplantation and the Role of Tissue Amogh Sivarapatna Innovation, Queensland University of Development of Capillary-like Structures in Cardiovascular Institute, Stanford University Stem Cell-Seeded Strontium Incorporated (6); University of Southern California (7) Adipose Derived Mesenchymal Stem Cell Engineering to Develop Replacement Modulation of Arterio-Venous Identity in Technology, Brisbane, Australia (1); Psoriatic Skin Substitutes (2); Center for Tissue Regeneration, Repair, Hydroxapatite Han-Tsung, Liao (1,2); Chien-Tzung Chen Organs for Patients in Need Endothelial Cells Derived from Human Australian Prostate Cancer Research Center, Raif Eren Ayata (1,2); Michèle Auger (3); and Restoration, Veterans Administration Palo Sunitha Chandran (1); Suresh S Babu (2); 213 (1); Jyh-Ping, Chen (2) Jason A. Wertheim, MD, PhD (1, 2) Induced Pluripotent Stem Cells using Shear Translational Research Institute, Brisbane, Roxane Pouliot (1,2) Alto Health Care System (3); Department of Hari Krishnan V.S. (3); Harikrishna Varma (4); Francis Fernandez Division of Trauma Plastic Surgery, Comprehensive Transplant Center, Stress Australia (2) Faculté de Pharmacie, Université Laval, Materials Science and Engineering, Stanford Annie John (5) Resurfacing Articular Cartilage in a Caprine Department of Plastic and Reconstructive Department of Surgery, Northwestern Amogh Sivarapatna (1); Mahboobe Ghaedi Québec, Canada (1); Centre LOEX de University (4) Transmission Electron Microscope, Bio Model: Adipose Derived Stem Cells & Surgery, Craniofacial Research Center, University Feinberg School of Medicine, (2); Julio Mendez (2); Wei Wu (3); Yibing 234 l’Université Laval, Québec, Canada (2); Medical Technology Wing, Sree Chitra Engineered Ceramics Chang Gung Memorial Hospital, Taiwan Northwestern University, Chicago, Illinois Qyang (4); Laura E Niklason (1, 2) Esmaiel Jabbari Département de Chimie, Regroupement 246 Tirunal Institute for Medical Sciences & Francis B. Fernandez (1); Suresh S. Babu (2); (1); Department of Chemical and Materials (1); Institute for BioNanotechnology in Department of Biomedical Engineering, Yale Inert Patterned Matrix for Engineering Cancer québécois de recherche sur la fonction, Traci Goodchild Technology (1); Bioceramics Laboratory, Sachin J. Shenoy (3); Harikrishna Varma (4); Engineering, Chang Gung University (2) Medicine and Chemistry of Life Processes University(1); Department of Anesthesiology, Stem Cell Niche la structure et l’ingénierie des protéines Preclinical Evaluation of Vasomotion at 12 Bio Medical Technology Wing, Sree Chitra Annie John(5) Institute, Northwestern University, Chicago, Yale University (2); Department of Surgery, Samaneh K. Sarvestani, Esmaiel Jabbari (PROTEO), Centre de recherche sur les Months in a Bioresorbable Vascular Scaffold Tirunal Institute for Medical Sciences & Transmission Electron Microscope, Bio 218 Illinois (2) Yale University (3); Department of Medicine, University of South Carolina, Columbia, matériaux avancés (CERMA), Québec, Implanted in Porcine Coronary Arteries Technology (2); Division of Laboratory Medical Technology Wing, Sree Chitra Susan Mani Yale University (4) South Carolina Canada (3) Traci T. Goodchild (2); James J. Benham (1); Animal Science, Bio Medical Technology Tirunal Institute for Medical Sciences & Expansion of Mesenchymal Stem Cells 225 Steve H. Hsu (1); Deepal K. Panchal (2); Wing, Sree Chitra Tirunal Institute for Technology (1); Bioceramics Laboratory, at Physiological Oxygen Levels Delays Qian Ye 230 235 241 Shashi F. Bhushan (3); David J. Lefer (3); Medical Sciences & Technology (3); Bio Medical Technology Wing, Sree Chitra Senescence In Vitro and In Vivo Evaluation of Placenta Xuefeng Yang Tsuyoshi Kimura Srishti Bhutani Laura E.L. Perkins (1); Alexander J. Sheehy Bioceramics Laboratory, Bio Medical Tirunal Institute for Medical Sciences & Susan Mani; Renuka R. Nair Derived Adherent Cells Cultured on Human Urine-derived Stem Cells Originate Preparation of Decellularized Melanoma Vascular Differentiation of Cardiac Progenitor (1); Byron J. Lambert (1); Daniel L. Cox (1); Technology Wing, Sree Chitra Tirunal Technology (2); Division of Invivo Models & Division of Cellular & Molecular Cardiology, Decellularized Human Placental Vascular from Parietal Stem Cells Tissue using High Hydrostatic Pressure Cells in VEGF-immobilized PEG Hydrogel Richard J. Rapoza (1) Institute for Medical Sciences & Technology Testing, Bio Medical Technology Wing, Sree Sree Chitra Tirunal Institute for Medical Scaffold Xuefang Yang (1); Rongpei Wu (1,2); Guihua Technology Scaffold Abbott Vascular, Santa Clara, California (1); (4); Transmission Electron Microscope, Bio Chitra Tirunal Institute for Medical Sciences Sciences & Technology Qian Ye; Jia-Lun Wang; Xuan Guo; Xiaowei Liu (1); Yuxin Fan (3); Jan Rohozinski (1,4); Mitsuki Ueki (1); Tsuyoshi Kimura (1); Naoko Srishti Bhutani (1); Apoorva S. Salimath (2); Saint Joseph’s Translational Research Institute, Medical Technology Wing, Sree Chitra & Technology (3); Bioceramics Laboratory, Deng; Joseph Gleason; Shuyang He; Uri Anthony Atala (1) and Yuanyuan Zhang (1) Nakamura (1); Kwangwoo Nam (1); Toshiya Archana V. Boopathy (1); Andres J. Garcia (2); Atlanta, Georgia (2); 3 Emory University. Tirunal Institute for Medical Sciences & Bio Medical Technology Wing, Sree Chitra 219 Herzberg; Mohit B. Bhatia; Wolfgang T. Wake Forest Institute for Regenerative Fujisato (2); Akio Kishida (1) Michael E. Davis (1,3) Atlanta, Georgia (3) Technology (5) Tirunal Institute for Medical Sciences & Bryan Marshall Hofgartner; Robert J. Hariri Medicine, Wake Forest School of Medicine, Tokyo Medical and Dental University (1;) Department of Biomedical Engineering, Technology (4); Transmission Electron Cell Generated Complete Human Skin, a Winston-Salem, North Carolina (1); Osaka Institute Technology (2) Georgia Institute of Technology and Emory 247 210 Microscope, Bio Medical Technology Wing, Wound Healing Model 226 The First Affiliated Hospital, Sun Yat-sen University (1); School of Mechanical Bernadine Idowu Ethan Daley Sree Chitra Tirunal Institute for Medical Xunwei Wu (1); Minh Vo (1); Bryan Marshall Xiao Zhao University, Guangzhou, China (2); John 236 Engineering, Georgia Institute of Technology Engineering Stem Cell Niches- a Model for Phenotypic Differences in White-tailed Deer Sciences & Technology (5) (1) The Role of Neural Precursor Cells and Self Welsh Cardiovascular Diagnostic Laboratory, Shantanu Pradhan (2); Division of Cardiology, Emory University Vascularization and Mineralization Antlerogenic Progenitor Cells and Marrow- MWV Cell Assembling Peptides in Spinal Cord Repair Department of Pediatrics, Baylor College of A Tissue-engineered Model of Breast Cancer (3) Bernadine D. Idowu; Eman Alfayez; Lucy Di Derived MSC 214 Xiao Zhao (1); Gordan Liu (2); Yang Liu (2); Medicine, Houston, Texas (3); Department of Formed Using PEG-fibrinogen Hydrogel Silvio Ethan L.H. Daley (1,2); Andrea I. Alford (2); Anthony Frei 220 Jian Wang (2); Kajana Satkunendrarajah (2); Obstetrics and Gynecology, Baylor College of Microspheres 242 Biomaterials, Tissue Engineering & Imaging Steven A. Goldstein (1,2) In Vivo Effects of Macroporous Scaffolds on Vanessa Ragaglia Michael Fehlings (2,3) Medicine, Houston, Texas (4) Shantanu Pradhan (1); Jacob M. Clary (1); Rachel Campbell Group, Kings College London, Dental Biomedical Engineering, University Non-Human Primate Mesenchymal Stem An Acellular Biodegradable Scaffold for Department of otolaryngology - head and Elizabeth A. Lipke (1) In Vivo Microanastomosis of Microvessel Institute, London, United Kingdom of Michigan (1); Orthopaedic Surgery, Cells Tendon Regeneration in a Rabbit Pre-Clinical neck surgery, University of Toronto, Ontario, 231 Chemical Engineering, Auburn University (1) Containing Tissue-Engineered Constructs: The University of Michigan (2) Anthony W. Frei (1,2); Melissa A. Willman Model Canada (1); Spinal Program, Krembil Shuo Yin Final Frontier 248 (1); Dong Mei Han (1); Alexander Rabassa Vanessa Ragaglia; Priya R. Baraniak Neuroscience Centre, University Health Chondrogenic Transdifferentiation of Human 237 Rachel Campbell (1); Karina A. Hernandez Eric Nguyen (1); Ethan Yang (1,4); Jaime A. Giraldo (1,2); Research Operations, Garnet Network, Toronto, Ontario, Canada (2); Dermal Fibroblasts Stimulated with Cartilage Nathan Rohner (1); Tatiana Boyko (1) , Jeremiah Joyce (1), Hydrogel Array for Screening Endothelial Dora M. Berman (1); Norma S. Kenyon BioTherapeutics, Inc. Institute of Medical Sciences, University of Derived Morphogenetic Protein1 Tumors Change the Elastic and Viscoelastic Adam M. Jacoby (1); Jason A. Spector (1) Cell Behavior in Three-dimensional Synthetic (1,2,3); Cherie L. Stabler (1,2,3): Toronto, Ontario, Canada (3) Shuo Yin (1,2); Lian Cen (2) Wei Liu (1,2); Properties of Draining Lymph Node Tissues Plastic Surgery, Weill Cornell Medical College Environments Diabetes Research Institute, University 221 Yilin Cao (1,2) Nathan A. Rohner (1); Jacob McClain (1); (1) Eric Nguyen (1); Matthew Zanotelli (1); Cody of Miami (1); Department of Biomedical Jason Schulte Department of Plastic and Reconstructive Sara L. Tuell (1); Susan N. Thomas (1) Bindl (1); William Murphy (1,2) Engineering, University of Miami (2); Decellularized and Vascularized Scaffolds Surgery, Shanghai 9th People’s Hospital, Mechanical Engineering, Georgia Institute of Biomedical Engineering, University of Department of Surgery, University of Miami for Tissue-Engineered Regeneration of Shanghai Jiao Tong Technology (1) Wisconsin-Madison (1); Orthopedics and (3); Department of Biochemistry and Myocardium University School of Medicine, Shanghai, Rehabilitation, University of Wisconsin- Molecular Biology, University of Miami (4) Jason B Schulte (1); Dan T. Simionescu (2); China (1); National Tissue Engineering Madison (2) Agneta Simionescu (2) Center of China, Shanghai, China (2) Bioengineering, Clemson University (1); Patewood/CU Bioengineering Translational Research Center, CUBEInc (2)

38 39 POSTER SESSION II – TUESDAY, NOVEMBER 12, 2013 2:30 – 4:00 PM POSTER SESSION II – TUESDAY, NOVEMBER 12, 2013 2:30 – 4:00 PM

249 255 260 265 270 276 281 Beth Pollot Jing Yang Carlos Landa Aaron Mohs Debora Petropolis Denys Lisovyy Goro Kuramoto Evaluation of Scaffolds for Treating Fabrication of Vascularised Tissues using 3D Mobilized Mesenchymal Stem Cell Cultures Magnetic Resonance Imaging Engineering a Hepatic In Vitro 3D Model to In Vivo Tissue-Engineered Artificial Skin Preventive Effect of Oral Mucosal Epithelial Volumetric Muscle Loss Printing from Ovine Peripheral Blood Characterization of Regenerating Bladder in Study Human Parasitic Infection Grown to Resemble the Native Skin Cell Sheets on Endometrial Adhesion Beth E. Pollot (1,2); Christopher R. Rathbone Jing Yang; Kevin Shakesheff Carlos Landa-Solís (1); Carmina Ortega- a Murine Subtotal Cystectomy Model Debora B. Petropolis (1); Nancy Guillen (1) Denys E. Lisovyy; Sergey M. Chudnykh Goro Kuramoto (1,2); Soichi Takagi (2); Ken (2); Joseph C. Wenke (2); Teja Guda (1,2) School of Pharmacy, University of Sanchez (1) Julio Granados-Montiel (1) , Aaron M. Mohs (1,2); Mona Zarifpour (1); Cell Biology of Parasitism Unit, Institut Moscow State University of Medicine and Ishitani (1); Tatsuya Shimizu (2); Masayuki Biomedical Engineering, The University of Nottingham Anell Olivos-Meza (2); Hugo Lecona-Butrón Sneha Kelkar (1); Martha A. Kahlson (1); Pasteur, Paris, France (1) Dentistry Yamato (2); Teruo Okano (2); Hideo Matsui Texas at San Antonio (1); Extremity Trauma (3); Clemente Ibarra-Ponce de Leóna,(1,2,4); Frank C. Marini (1); George J. Christ (1,2) (1) and Regenerative Medicine, United States 256 Carlos Pineda-Villaseñor (5) Wake Forest Institute for Regenerative 271 277 Department of Obstetrics and Gynecology, Army Institute of Surgical Research (2) Daniel Young Tissue Engineering, Cell Therapy and Medicine, Wake Forest University Health Gabriela Piñón Zárate Denys Lisovyy Tokyo Women’s Medical University Role of VEGF-mimetic Peptide Presentation Regenerative Medicine Unit (1); Sports Sciences, Winston-Salem, North Carolina GK-1 Improves the Immune Response of Autologous Cells Of Hair Follicles as an (1); Institute of Advanced Biomedical 250 for the Vascularization of Hydrogel Scaffolds Orthopaedics and Arthroscopy Department (1); Wake Forest - Virginia Tech School of Bone Marrow Dendritic Cells Target with Alternative to Hair Transplantation. Clinical Engineering and Science, Tokyo Women’s Wen Seeto Daniel A. Young (1); Elizabeth J. English (1); (2); Animal Care Facility (3); Biotechnology Biomedical Engineering and Sciences, Wake MAGE Antigen in Mice with Melanoma Results. Medical University (2) Endothelial Progenitor Cell Retention and Georgia Papavasiliou (1) Department (4); Research Direction; Forest University Health Sciences, Winston- Gabriela Piñón (1); Beatriz Hernández (1); Denis E. Lisovyy (1,2); Elena L. Vilitkevich Rolling on PEG-peptide Hydrogels Exposed Biomedical Engineering Department, Illinois National Institute of Rehabilitation, Mexico Salem, North Carolina Miguel Herrera (1); Katia Jarquín (1); Patricia (2); Sergey M. Chudnykh (1) 282 to Shear Institute of Technology (1) City, Mexico (5) Torres(1); Daniel Santillán (1); Paulina Villena General Surgery, Moscow State University Mohammad Reza Dastouri Wen J. Seeto (1); Yangzi Tian (2); Elizabeth 266 (1); Marlene Zempoaltecatl (1); Sandra of Medicine and Dentistry, Moscow, Russian In Vitro Differentiation of Endothelial A. Lipke (1) 257 261 Sudharsan Periyasamy-Thandavan Acevedo (1); Andres Castell (1) Federation (1); Experimental Cardiology, Progenitor Cells Generated From Mouse Chemical Engineering, Auburn University Chao Zhang Yijun Liu Differential Expression of MicroRNAs in Laboratory of Immunotherapy, Cell Biology Russian Cardiology Research and Production Induced Pluripotent Stem Cells (1); Chemical and Biomolecular Engineering, Enhance Myogensis and Innervation after Analysis of Human Mesenchymal Stem Human Mesenchymal Stem Cells with Department, Medicine School, Mexico City, Complex, Moscow, Russian Federation (2) Mohammad Reza Dastouri (1); Aynur Polytechnic Institute of New York University Implantation of Urine-Derived Stem Cells Cell Metabolism during Expansion and Age May Be Related to Musculoskeletal Mexico (1) Karadag (2); Deniz Balci (1); Gunseli (2) Expressing VEGF in Collagen-I Hydrogel Osteogenic Differentiation under Different Disorders 278 cubukcuoglu Deniz (1); Serkan Durdu (3); Chao Zhang, Guihua Liu, Shantaram Oxygen Tensions Sudharsan Periyasamy-Thandavan (1,3); 272 Paul Schiller Ahmet Ruchan Akar (3); Alp Can (4) 251 Bharadwaj, Anthony Atala and Yuanyuan Yijun Liu (1); Nathalie Muñoz (2); Teng Ma Sergi Mas (2); Sadanand Fulzele( 5); Filippos Tourlomousis Non-Expanded MIAMI (ne-MIAMI) Cells Department of Stem Cell, Ankara University Emily Shearier Zhang (1) Xingming Shi( 6,7); Norman Chutkan (5); Investigation of Cell-scaffold Dimensional Directly Isolated from Human Bone Marrow: Biotechnology Institute, Ankara, Turkey (1); Pre-vascularized Cell Sheets Wake Forest Institute for Regenerative Chemical and Biomedical Engineering, Randy Ruark (5); John Hinson (5); Monte Metrology using 3D Melt-electrospun Characterization, Interaction with Scaffolds Department of Medical Biology, Ankara Emily R. Shearier (1); Lijun Zhang (1); Medicine, Wake Forest School of Medicine Florida State University(1); Chemistry, Florida Hunter (5); Raymond Corpe (5); Hongyan Xu Scaffolds and Therapeutic Applications University, Ankara, Turkey (2); Department of Zhaoqiang Zhang (1); Feng Zhao (1) Winston-Salem, North Carolina State University (2) (4); Carlos Isales( 5,6,7); Mark W. Hamrick Filippos Tourlomousis (1); Robert C. Chang Gianluca D’Ippolito, (1,2); Gaetan J.R. Cardiovascular Surgery, Heart Center, Ankara Biomedical Engineering, Michigan (3,5,6,7); William Dee (2) Delcroix (1,2); H. Thomas Temple (1); Paul C. University, Ankara, Turkey (3); Department of Technological University (1) 262 Charlie Norwood Veterans Administration Mechanical Engineering, Stevens Institute Schiller (1,2) Histology & Embryology, Ankara University Shunya Takagi Medical Center, Augusta, Georgia (1); of Technology (1); Mechanical Engineering, University of Miami (1); Bruce W. Carter School of Medicine, Ankara, Turkey (4) 252 LATE BREAKING POSTERS Effect of Electrical Stimulation of Tissue- Universitat de Barcelona, Spain, the Stevens Institute of Technology (2) Miami Veterans Administration Healthcare Sami Somo Engineered Skeletal Muscle Departments of (3); Cellular Biology and System, Miami, Florida (2) 283 Vascularized Tissue Formation in Gradient 258 Shunya Takagi (1); Shouhei Hatoma (1); Anatomy (3); Biostatistics and Epidemiology 273 Seung-Yup Ku Biomaterials is Controlled by Pore Samuel LoPresti Takafumi Kamon (1); Tomohiro Nakamura (4); Orthopaedic Surgery, and the Institutes Andrés Castell Rodríguez 279 Functional Alterations in Human Pluripotent Interconnectivity Effect of Extracellular Matrix Source Tissue (2); Toshia Fujisato (1) of (5); Molecular Medicine and Genetics and Grafts of Human Cadaveric Cancellous Bone Keith VanDusen Stem Cell-Derived Cardiomyocyte due to In Sami Somo (1,3); Banu Akar (1,3); Jeffery on Remodeling of Temporomandibular Joint Department of Biomedical Engineering, (6); Regenerative and Reparative Medicine, Chips Seeded with Autologous Osteoblasts Engineered Skeletal Muscle Units for Repair Vitro Culture and Reversing Effect of C. Larson (1,3); Alyssa A. Appel (1,3); Meniscus Replacement Osaka Institute of Technology (1); Division of Georgia Regents University, Augusta, to Treat Diaphyseal Pseudoarthrosis of Volumetric Muscle Loss in the Tibialis Vitamin C Hamidreza Mehdizadeh (2); Ali Cinar (2); Samuel LoPresti (1,2); William Chung (2,3); Human Sciences, Section for Health-related Georgia (7) Andres Castell (1); Miguel Herrera (1); Anterior Muscle of a Rat Seung-Yup Ku (1,2); Yoon Young Kim (1,2); Eric M. Brey (1,3) Alejandro Almarza (1,2); Stephen Badylak Physical Education, Faculty of Engineering, Beatriz Hernández (1); Judith Alvarez (1); Keith W. VanDusen (1); Brian C. Syverud (2); Seok Hyun Kim (1,2); Young Min Choi (1,2) Biomedical Engineering, Illinois Institute (2,4); Bryan Brown (1,2) Osaka Institute of Technology (2) 267 Gabriela Piñon (1); Katia Jarquin (1); Sandra Lisa M. Larkin (1,2) Institute of Reproductive Medicine and of Technology (1); Chemical Engineering, Bioengineering, University of Pittsburgh Karin Wartella Acevedo (1); Pablo Castell (2); Sergio Molecular & Integrative Physiology, Population, Medical Research Center, Seoul, Illinois Institute of Technology (2); Edward (1); McGowan Institute for Regenerative 263 An e-Incubator for Dynamic Magnetic Guevara (2); Teofilo Bandera (2); Raul Flores University of Michigan (1); Biomedical Korea (1); Department of Obstetrics and Hines Junior Veterans Administration Medicine (2); Oral and Maxillofacial Ang-Chen Tsai Resonance Microscopy of Bone Tissue (3); Francisco Limon(3); Enrique Obermeier Engineering, University of Michigan (2) Gynecology, Seoul National University Hospital (3) Surgery, University of Pittsburgh (3); Surgery, Human Mesenchymal Stem Cells in 3D Engineered (3); College of Medicine, Seoul, Korea (2) University of Pittsburgh (4) Aggregates: Influence of Endogenous Karin A Wartella (1); Vahid Khalilzad-Sharghi Department of Cell and Tissue Biology, 280 253 Extracellular Matrix and Aggregate Size on (1); Shadi F Othman (1); Huihui Xu (1) Medicine School, Universidad Nacional Mona Zarifpour 284 Aline Thomas 259 Cell Survival Department of Biological Systems Autónoma de México, México City, México Characterization of Functional Bladder Yonggang Pang Lentivirus-mediated Sonic Hedgehog Kouji Shima Ang-Chen Tsai; Junho Kim; Teng Ma Engineering, University of Nebraska-Lincoln (1); Hospital General, ISSSTE, Iguala Gro. Regeneration in Mice Analyzing Structure and Function of Delivery for Vascularization of Poly(ethylene Hydrostatic Pressure Treatment for making Chemical and Biomedical Engineering, (1) and Sanatorio de Padre Jesús, Iguala, Gro, Mona Zarifpour (1); Jason M Sandberg (1); Vascularization in Engineered Bone Tissue glycol) Scaffolds In Vivo Acellular Dermis Grafts Florida State University Mexico (2); Tissue Bank Novoinjertos, Manasi Vadhavkar (1); Sneha Kelkar (1); by Video-rate Intravital Microscopy and 3D Aline Thomas (1); Andrew Gomez (1); Kouji Shima (1); Liempham Hieu(2); Atsushi 268 México City, México (3) Aaron M. Mohs (1,2); Frank C. Marini (1); Image Processing Lonnie Shea (2) Mahara (3); Naoki Morimoto (2,4); Tetsuji 264 Parvin Forghani Karl-Erik Andersson (1); George J. Christ (1,2) Yonggang Pang (1); Craig M. Neville (1); Biomedical Engineering, Northwestern Yamaoka (3); Shigehiko Suzuki (2); Toshiya Julia Raykin MDSCs Modulation by Silibinin in Murine 274 Wake Forest Institute for Regenerative Brian E. Grottkau (1) University (1); Chemical and Biological Fujisato (1); A Theoretical and Experimental Model to Breast Tumor Model Pamela BrownBaer Medicine, Winston-Salem, North Carolina Department of Orthopaedic Surgery, Engineering, Northwestern University (2) Department of Biomedical Engineering, Predict Failure of Tissue Engineered Blood Parvin Forghani (1,2); Edmund K Waller (2); Spatial Bone Healing Patterns in a Bone (1); Wake Forest – Virginia Tech School Massachusetts General Hospital (1) Osaka Institute of Technology (1); Vessels School of Public Health, Department of Notch Defect Model in Pigs: A Clinical CT of Biomedical Engineering and Sciences, 254 Department of Plastic and Reconstructive Julia Raykin (1,2); Alexander I. Rachev (3); Pathobiology, Tehran University of Medical Analysis Winston Salem, North Carolina (2) Lei Tian Surgery, Graduate School of Medicine, Kyoto Rudy L. Gleason (1,2,3) Sciences, Tehran, IR(1); Department of Pamela R. BrownBaer (1); David T. Silliman Impact of Pericytes On Vessel Formation and University (2); Department of Biomedical Department of Biomedical Engineering, Hematology and Medical Oncology, Emory (1); Robert G. Hale (1); Teja Guda (1,2) Anastomosis In Prevascularized Tissues Engineering, National Cerebral and Georgia Institute of Technology (1); Petite University, Atlanta, Georgia (2) United States Army Institute of Surgical Lei Tian (1,2); Anna S. Aledia (1,2); Cardiovascular Center (3); Department of Institute for Bioengineering and Biosciences, Research (1); University of Texas at San Christopher C.W. Hughes (1,4); and Steven Plastic and Reconstructive Surgery, Kansai Georgia Institute of Technology (2); and 269 Antonio (2) C. George (1,2,3) Medical University Takii Hospital (4) School of Mechanical Engineering, Georgia Susanna Miettinen Department of Biomedical Engineering, Institute of Technology (3) Immunological Evaluation of Human 275 University of California, Irvine (1); The Adipose Stem Cells Cultured in Different Laura McCallum Edwards Life Sciences Center for Advanced Serum Conditions versus Xenofree/Serumfree Metabolic and Structural Changes in Cardiovascular Technologies, University Condition Diabetic Cardiomyopathy; In Vivo and In of California, Irvine (2); Department of Susanna Miettinen (1); Mimmi Patrikoski (1); Vitro Models Chemical Engineering and Materials, Jyrki Sivula (1); Bettina Mannerström (1) Laura McCallum; Thomas Larrew; James University of California, Irvine (3); Group, Institute of Chow; Jason Schulte; Dan Simionescu; Department of Molecular Biology and Biomedical Technology and BioMediTech, Agneta Simionescu Biochemistry, University of California, Irvine University of Tampere, Tampere, Finland (1) Bioengineering, Clemson University (4)

40 41 CONGRATULATIONS TO THE TERMIS-AM 2013 CONFERENCE & EXPOSITION PLANNING TEAM November 2013

Dear Students, Young Investigators, and Conference Attendees, Robert Guldberg, PhD, Conference Chair and TERMIS-AM Chapter Chair, Georgia Institute of Technology Welcome to Atlanta and thank you for joining us at TERMIS-AM 2013!

Todd McDevitt, PhD, Scientific Advisory Committee Chair, The TERMIS Student and Young Investigator Section Americas (SYIS-AM) Meeting Committee Georgia Institute of Technology has prepared a special program for students and post-docs to foster career development Megan McDevitt, CMP, Local Arrangements Chair, Georgia Institute of Technology and encourage networking and interaction with experts in the field. We hope you enjoy our program and find it stimulating! Tracy Hookway, PhD, SYIS-AM Vice-Chair, Georgia Institute of Technology

The SYIS program opens on Sunday afternoon with tours of Georgia Institute of Technology’s Executive Production Provided by research laboratories. Enjoy a Stinger Shuttle ride from the Hyatt downtown to Georgia Forecast Technology Group Institute of Technology’s campus in midtown. You will then get to walk through some www.conferencestrategists.com biomedical research laboratories and hear about the cutting-edge research going on at Anita Caufield, MHA Georgia Institute of Technology. Andrea Lubienski, CMP Events continue throughout the day on Monday beginning with a Career Panel Discussion Gina Saxton over lunch (sign-ups at registration). Come hear about career paths from experts in academia, industry and the NIH. Monday afternoon SYIS-AM is taking part in an outreach Conference Liaison for TERMIS program to expose Atlanta high-school students to a scientific conference. We will be Sarah Wilburn, TERMIS Administrator demonstrating biomedical principles to these students through hands-on demonstrations. On Monday evening, the SYIS is hosting a reception Alma Cocina. This will be an

TERMIS-AM Treasurer Welcome opportunity to network with fellow SYIS attendees as well as join us at our SYIS-AM Bill Tawil, Baxter BioScience & UCLA Business Meeting. Come and enjoy drinks and hors d’oeuvres, meet new people, and learn how you can be a part of SYIS and the future of regenerative medicine! Special thanks to Bob Nerem, PhD, Georgia Institute of Technology for organizing the Opening Symposium - “Tissue Engineering & Regenerative On Tuesday, join us for the Student Meet Mentor Lunch (sign-ups at registration). Don’t miss Medicine: Origins and its Evolution”. this opportunity to have lunch and talk with leaders in the field of regenerative medicine.

SYIS is excited to host the SYIS-AM Poster Competition. The top 25 student and young Mark van Dyke, PhD, Virginia Polytechnic Institute and State University, investigator posters (authors were notified prior to the conference) will be judged by senior Tim Bertram, DVM, PhD, Tengion and the TERMIS-AM Industry Committee for faculty members, with awards for 1st place ($300), 2nd place ($200), and 3rd place ($100). organizing the Bench to Business Workshop. Poster award winners will be announced at the closing ceremony on Wednesday at 4:30pm.

Milica Radisic, PhD, University of Toronto, for organizing the Women in Tissue This year we have been able to expand our events by including more conference attendees Engineering & Regenerative Medicine Luncheon. as well as adding new events such as our SYIS Outreach Program. We would like to thank the NSF for a grant in support of these expansion efforts, as well the Stem Cell Engineering Center at Georgia Institute of Technology and the Regenerative Engineering and DISCLAIMER Medicine Research Center at Georgia Institute of Technology and Emory University for their The material presented at the TERMIS-AM 2013 Conference has been made available by the Tissue Engineering sponsorship of the lab tours and poster awards. and Regenerative Medicine International Society - Americas (TERMIS-AM) for educational purposes only. The material is not intended to represent the only, nor necessarily best, method or procedure appropriate for the Congratulations We hope you have a fantastic TERMIS-AM Meeting and look forward to meeting you! medical situations discussed, but rather is intended to present an approach, view, statement or opinion of the faculty which may be helpful to others who face similar situations. Tissue Engineering and Regenerative Medicine International Society - Americas (TERMIS-AM) disclaims any and all liability for injury or other damages resulting Kind Regards, to any individual attending the meeting and for all claims which may arise out of the use of the techniques demonstrated therein by such individuals, whether these claims shall be asserted by physician or any other Tracy Hookway person. Rebecca Dahlin SYIS-AM Chair SYIS-AM Vice Chair NOTICE No part of this publication may be translated or reproduced, in any form or by any means, without written Satyavrata Samavedi Sean Murphy permission from TERMIS-AM. No photography, video, audio recording or reproduction of any kind may be used SYIS-AM Secretary SYIS-AM Professional Development Committee Chair during any portion of the TERMIS-AM 2013 Conference. TERMIS-AM reserves all of its rights to such materials, and commercial recording or reproduction is specifically prohibited. This includes, but is not limited to, digital and film photography, videography, cellular phones, and other image or audio recording devices. Johnny Lam Kimbery Ferlin SYIS-AM Treasurer SYIS-AM Communications Officer

42 43 TERMIS-AM STUDENT & YOUNG INVESTIGATOR SECTION (SYIS) STUDENT POSTER COMPETITION – POSTERS ARE FOUND IN THE TERRACE FOYER

Campus Tours Opening Reception 1 Immunomodulation 7 Rejuvenating Tissue/Organ Function Radovan Borojevich (5); Jose Mauro Granjeiro Sunday, November 10th from 12:00 – 2:00 PM Monday, November 11th James Chow Joshua Jaeyun Kim (2); Leandra Baptista (2,6); Jorge VL da Silva (1); 7:00 PM at Alma Cocina Immunomodulatory Effects of Autologous A Novel Enzyme Degradable Hydrogel Based Vladimir Mironov (1 TERMIS-AM SYIS is pleased to host Tours of Adipose-Derived Stem Cells on Scaffold Cell Sheet Harvest and Transfer System with High Division of 3D Technologies, Renato Archer the Georgia Institute of Technology Campus TERMIS-AM SYIS is pleased to host the Opening Remodeling in Diabetes Cell Viability Center for Information Technology, Campinas, SP, on Sunday, November 10th during the TERMIS- Reception on the evening of Monday, November James P. Chow (1); Harleigh J. Warner (1); Dan T. Joshua Jaeyun Kim (1); Joyce Wong (1) Brazil (1); Division of Bioengineering, National AM Atlanta Meeting. This year SYIS-AM will be 11th to celebrate the opening of the 2013 TERMIS- Simionescu (1); Agneta Simionescu (1) Biomedical Engieering, Bosotn University Institute of Metrology, Quality and Technology offering the chance to visit the campus of Georgia AM Meeting in Atlanta. The SYIS reception is open Bioengineering, Clemson University (1) (Inmetro), Duque de Caxias, RJ, BRAZIL (2); Riga 8 Cell Engineering/Synthetic Biology Stradins University Institute of Technology and tour the research to all students and young investigators and will be 2 Engineering Morphogenesis NaJung Kim laboratories. Transportation will be provided from a fun evening to kick-off the TERMIS-AM meeting. Katy Hammersmith Combination of Small RNAs Enhances Muscle 14 Engineering of Matrix Composition the conference center to the campus. This event is an opportunity to catch up with friends Engineering the Microenvironment of Development Tara S and meet other young scientists while enjoying food Embryoid Bodies via Heparin-modified Gelatin NaJung Kim (1); James J. Yoo (2); Anthony Atala Bioengineered Fibrin Matrix for In vitro Career Opportunities Discussion Panel and drinks. We will also hold our annual business Microparticle Incorporation (3); Sang Jin Lee (4) differentiation of Circulating progenitors to Monday, November 11th at 11:30 AM meeting and discuss the purpose and goals of the Katy A. Hammersmith(1); Andres M. Bratt-Leal(1); Wake Forest Institute for Regenerative Medicine, Neurons and In vivo survival in Rat Spinal cord The Learning Center SYIS-AM for the 2013 conference, as well provide Marissa T Cooke (1); Christian Mandrycky(1); Wake Forest School of Medicine, Wake Forest Injury Model information on the upcoming SYIS events. Todd C. McDevitt (1,2) University Tara.S (1); Lissy.K Krishnan (1) TERMIS-AM SYIS is pleased to host the Career Biomedical Engineering, Georgia Institute of Thrombosis Research Unit, Biomedical Opportunities Discussion Panel on Monday, Student Meet Mentor Lunch Technology(1); The Parker H. Petit Institute for 9 Regeneration-Inducing Biomaterials Technology Wing, Sree Chitra Tirunal November 11th at lunch during the TERMIS- Tuesday, November 12th at 11:30 AM Bioengineering & Bioscience, Georgia Institute of Gaurav Lalwani Institute for Medical Sciences & Technology, Technology (2) Cytocompatibility of Macroporous All-Carbon Trivandrum-695012, Kerala, India (1) AM Atlanta Meeting. This discussion panel will Hanover AB scaffolds for Tissue Engineering Applications consist of scientific leaders representing careers 3 Rejuvenating Tissue/Organ Function Gaurav Lalwani, Yahfi Talukdar, Balaji Sitharaman 15 Rejuvenating Tissue/Organ Function in academia, industry, government agencies TERMIS-AM SYIS is pleased to host the Student Christopher Heylman Department of Biomedical Engineering, Stony Laura Struzyna and institutes and entrepreneurial activities. Meet Mentor Lunch on Tuesday, November 12 at Evaluation of the in vitro performance of human Brook University, Stony Brook, NY 11794-5281 Restoring Brain Circuitry Using Micro-Tissue This is a great opportunity for students and lunch during the TERMIS-AM Atlanta Meeting. The osteogenic connective tissue progenitor cells Engineered Neural Networks young investigators to hear these experienced Student Meet Mentor Lunch gives students and derived from bone versus fat at clinically relevant 10 Manufacturing Technologies and Platforms Laura A. Struzyna (1); John A. Wolf (1); James scientists discussing their own career paths, the young investigators the opportunity to enjoy an oxygen tensions Hui Chong Lau P. Harris (1); Constance J. Mietus (1); Joseph P. opportunities and challenges of their chosen invigorating lunch with a mentor of your choice. Christopher M Heylman (1), Cynthia Boehm (1), Efficient Stem Cell Delivery System at Room Morand (1); D. K. Cullen (1) career, and providing advice on how you can Mentors include session chairs, members of the George F Muschler (1) Temperature Neurosurgery, University of Pennsylvania (1) achieve your career goals. This interactive panel Scientific Advisory Committee, and local industry Biomedical Engineering Department, Cleveland Hui-Chong Lau (1); In-Ho Jo (2); Jeong-Ok Lim (1) Clinic Lerner Research Institute (1) Department of Biomedical Science, Biomedical 16 Drug Delivery Principles is designed to facilitate open discussion, and to leaders. Research Institute, Kyungpook National Denise Sullivan allow students and young investigators to have 4 Engineering of Matrix Composition University, Daegu, Korea (1); Department of pNIPMAm Microparticles for Controlled BMP-4 their questions answered by the panel and other Student Poster Awards Henk Hoogenkamp Molecular Medicine, Ewha Womans University Delivery attendees. At previous meetings, this event has Presented at the Closing Ceremony on Bioscaffolds for organs in one: large seamless Medical School, Seoul. Korea (2) Denise D. Sullivan (1); Shalini Saxena (2); Anh H. been very beneficial for students and young November 14th at 4:30 PM hollow collagen spheres for organ regeneration Ngyugen (3); Jeff C. Gaulding (4); L. Andrew Lyon investigators thinking about pursuing a career in Centennial 3 Henk Hoogenkamp (1); Michiel Pot (1); Yi Sun (2); 11 Cell Engineering/Synthetic Biology (3,4); Todd C. McDevitt (1,3) any of these fields. Dorien Tiemessen (3); Wout F. Feitz (3); Willeke F. Diana Olvera Biomedical Engineering, Georgia Institute of Cash prizes will be handed out again this year Daamen (1); Toin H. van Kuppevelt (1) Coating of Titanium with Electrically Polarized Technology and Emory University (1); Materials Academia for the best posters among students and young Department of Biochemistry, Radboud University Hydroxyapatite Modulates Mesenchymal Stem Science and Engineering, Georgia Institute of George J. Christ, Ph.D. investigators. This is your chance to achieve special Medical Centre (1); Department of Radiology, Cell Adhesion Technology (2); Bioengineering and Bioscience, Professor of Regenerative Medicine, Urology, Physiology recognition among your peers and to earn some Radboud University Medical Centre (2); Diana Olvera (1); Keith Savino (2); Jason A. Georgia Institute of Technology (4);Chemistry and Inzana (1); Matthew Z. Yates (2); Hani A. Awad (1) Biochemistry, Georgia & Pharmacology and Translational Science bonus winnings for your research efforts and Department of Urology, Radboud University Core Faculty Member, Virginia Tech-Wake Forest Medical Centre (3) Biomedical Engineering, University of Rochester University School of Biomedical Engineering and success. (1); Chemistry, University of Rochester (2) 17 Rejuvenating Tissue/Organ Function SYIS Program Sciences 5 Vascularization Jillian Tengood Hillman Wake Forest Institute for Regenerative Medicine Student Poster Awards are sponsored by: Daphne Hutton 12 Immunomodulation Functionalization of Endothelial Cells with Vascularized Bone Development Within Sravanti Rangaraju Biodegradable Magnetic Nanoparticles for Industry Composite Scaffolds Targeting Trogocytosis: A Novel Strategy to Targeted Delivery Mark Van Dyke Daphne L Hutton (1); Josh Temple (1); Erika M Reduce Graft Versus Host Disease Following Jillian E Tengood (1); Ivan S. Alferiev (1); Robert J. Associate Professor Moore (1); Ben P Hung (1); Warren L Grayson (1) Allogeneic Transplant Levy (1); Michael Chorny (1) School of Biomedical Engineering and Sciences Biomedical Engineering, Johns Hopkins by Inhibiting the Generation of Cross-Dressed (1) Cardiology, Children’s Hospital of Philadelphia Virginia Tech University (1) Dendritic Cells Sravanti Rangaraju;Junghwa Choi;Cynthia R 18 Preclinical Animal Models Government agencies and institutes Student Co-Chairing (throughout the conference) 6 Rejuvenating Tissue/Organ Function Giver;Edmund K Waller David Burmeister Rosemarie Hunziker, PhD Carlos Kengla Emory University Development of a Porcine Deep Partial Thickness Tissue Engineering/Regenerative Medicine, Biomaterials, TERMIS-AM SYIS is pleased to announce the 3-D Integrated for Ear Contact Burn Model for Testing Tissue Engineered and Implantable Medical Devices Program Director opportunity for students and young investigators Reconstruction 13 Cell Engineering/Synthetic Biology Wound Healing Products National Institute of Biomedical Imaging and to serve as co-chairs for scientific sessions at the Carlos V Kengla (1,2); Hyun-Wook Kang (1); Rodrigo Rezende David M. Burmeister (1); Daniel C. Roy (1); Bioengineering TERMIS-AM Atlanta Meeting in November. This Anthony Atala (1); Sang Jin Lee (1,2); James J Yoo Biofabrication of tissue spheroids encaged into Bridget M. Ford (1); Shanmugasundaram Natesan National Institutes of Health one-of-a-kind event provides a unique platform for (1,2) interlockable microscaffolds (lockyballs) using (1); Robert J. Christy (1) students and young investigators to co-chair sessions Wake Forest Institute for Regenerative Medicine, two photon polymerization and high cell density United States Army Institute of Surgical Research, Entrepreneurial activities with leading scientists and get first-hand experience Wake Forest University (1); School of Biomedical seeding in micromolded non-adhesive hydrogel Extremity Trauma Research and Regenerative Anthony Ratcliffe, PhD moderating scientific discussions. At previous Engineering and Sciences, Wake Forest University, Rodrigo A Rezende (1); Karina R da Silva (2); Medicine (1) President and CEO meetings, this event has been hugely popular, and Virginia Tech (2) Frederico Pereira (1); Vladimir Kasyanov (3); Synthasome, Inc we hope to see several of you co-chairing sessions Aleksander Ovsianikov (4); Jurgen Stampfl (4); at this year’s meeting. 44 45 WFIRM YOUNG INVESTIGATOR AWARD WINNERS TERMIS-AM AWARDS PROGRAM - 2013 AWARDEES

The TERMIS-AM Council and Awards Committee would like to announce the recipients of the 2013 TERMIS-AM awards program. Each of the awardees will be acknowledged during this year’s Wake Forest Institute for Regenerative Medicine conference. Congratulations!

Young Investigator Award Lifetime Achievement Award: TERMIS-AM 2013 Conference and Exposition Robert M. Nerem, PhD, Professor Emeritus, George W. Woodruff School of Mechanical Engineering, The Wake Forest Institute for Regenerative Medicine is committed to the development and dissemination of novel Director, Georgia Institute of Technology & Emory Center for Regenerative Medicine, Parker H. Petit therapies for the repair and replacement of diseased tissues and organs. One way to achieve this goal is to foster Distinguished Chair for Engineering in Medicine and Institute Professor, Georgia Institute of Technology. the careers of young investigators to encourage them to find solutions to problems in regenerative medicine. As part Dr. Nerem has been active in bioengineering for more than thirty-five years. of this effort, the Wake Forest Institute for Regenerative Medicine Young Investigator Award was first awarded at the His initial interest was motivated by the possible role of fluid dynamics in atherosclerosis, and he has TERMIS-NA Conference and Exposition in 2008. The award is designed to recognize outstanding achievements by conducted fundamental research on problems in cardiovascular fluid dynamics. In 1981 he established members of the Tissue Engineering and Regenerative Medicine International Society (TERMIS) who are in the early a cell culture laboratory and began to study the influence of physical forces on anchorage-dependent stages of a career in regenerative medicine. mammalian cells, with much of this work focusing on the cells which make up a blood vessel. The award consists of a certificate, $2500 cash prize, and recognition at the 2013 TERMIS-AM Conference and Expo. This work led to his interest in tissue engineering, and he now is director of the Georgia Institute of Technology/Emory Center for the Engineering of Living Tissues (GTEC), an Engineering Research Center established in 1998 and We are pleased to announce this year’s winners: funded by the National Science Foundation. From 1995 to 2009 Nerem served as the director of the Parker H. Petit Institute for Dr. Minh Khanh Nguyen, PhD and Ms. Melissa A. Kinney Bioengineering and Bioscience (IBB), a research institute whose mission is to integrate engineering, information technology, and the life sciences in the conduct of biomedical research. In addition, he served on a part-time basis from 2003 to 2006 as the senior advisor for bioengineering in the National Institute Minh Khanh Nguyen, PhD, received his B.S.E. in Chemical Engineering of Health’s (NIH) newest institute, the National Institute for Biomedical Imaging and Bioengineering. In recognition of his work, from Ho Chi Minh City University of Technology, Vietnam, in 2003. Minh then he was elected to the National Academy of Engineering in 1988 and to the Institute of Medicine of the National Academy of went to graduate school at Sungkyunkwan University, South Korea in 2005 and Sciences in 1992. graduated with a Ph.D. in Polymer Science and Engineering in 2010 under the supervision of Dr. Doo Sung Lee. His graduate training was in design, synthesis He was elected a fellow of the American Academy of Arts and Sciences in 1998. Nerem is past president of the International Federation for Medical and Biological Engineering and past president of the International Union for Physical and Engineering and characterization of biomaterials for bioactive factor delivery. Following his Sciences in Medicine. He was also the founding president of the American Institute of Medical and Biological Engineering and he graduate studies, he has been working as a Postdoctoral Research Fellow in the served on the Science Board of the Food and Drug Administration from 2000 to 2003. In 2008 he received the Founders Award Alsberg Stem Cell and Engineered Novel Therapeutics laboratory in Department of from the National Academy of Engineering. Biomedical Engineering at Case Western Reserve University. Under the guidance of Nerem came to Georgia Institute of Technology in the winter of 1987 as a professor in the School of Mechanical Engineering and Dr. Eben Alsberg, he develops hydrogel biomaterial systems for controlled, sustained as the Parker H. Petit Distinguished Chair for Engineering in Medicine. He also has an appointment in the School of Chemical and and localized delivery of genes to guide stem cell differentiation. His research Biomolecular Engineering. Prior to coming to Georgia Institute of Technology, he was a professor and chairman in the Department interests lie in developing new biomaterials for bioactive factor delivery for tissue of Mechanical Engineering at the University of Houston from 1979 to 1986 and on the faculty at the Ohio State University from regeneration applications. 1964 to 1979.

Young Investigator Award: Melissa Kinney graduated with a Bachelor of Science in biomedical engineering

from Boston University in 2008. She is now an American Heart Association Alison P. McGuigan, PhD, Assistant Professor of the Department of Chemical Engineering Predoctoral Fellow and Ph.D. Candidate in Biomedical Engineering at Georgia and Applied Chemistry at the University of Toronto. Institute of Technology and Emory University where she is a senior member of the Engineering Stem Cell Technologies Laboratory led by Todd McDevitt. Melissa’s Dr. McGuigan is an Assistant Professor in Chemical Engineering and Applied Chemistry research interests integrate interdisciplinary perspectives from chemical and and the Institute for Biomaterials and Biomedical Engineering at University of Toronto. She mechanical engineering with stem cell and developmental biology and aim to obtained her undergraduate degree from University of Oxford, her PhD from University of Toronto working with Michael Sefton and completed post-docs at with develop technological advances for the integration of stem cells in translational George Whitesides and Stanford School of Medicine with Jeffrey Axelrod. regenerative applications. Her research specifically studies the morphogenesis of stem cells within three-dimensional microtissues to elucidate of the spatiotemporal dynamics of cell intrinsic interactions and signaling mediating tissue patterning, which Dr. McGuigan is a pioneer in the field of artificial tissue design and morphogenesis engineering. Her work uniquely combines will ultimately enable the development of novel strategies to engineer functional tissue engineering, microfabrication and developmental biology to assemble tissue systems for regenerative medicine and tissue structures. Her research in stem cell biology and engineering has earned drug screening applications. Specifically her team has created engineering tools to mimicking and quantitatively model tissue recognition through National Science Foundation and American Heart Association organizational processes that occur in the developing embryo. She has published 26 papers, a number of which have been key fellowships, the Petit Institute for Bioscience and Bioengineering F.L. Bud Suddath first demonstration contributions within the field appearing in journals such as PNAS, Nature Protocols, Biomaterials, Tissue Engineering and Integrative Biology. In recognition of her work Alison has received numerous awards: She received a Canadian Award and a Top Poster Award at the Society for Biological Engineering International Rhodes Scholarship from 2000-2002, a Canadian Institute of Health Training Program in Regenerative Medicine Fellowship in Conference on Stem Cell Engineering. Melissa has authored eight publications, a 2004, and a Stanford School of Medicine Dean’s Post-Doctoral fellowship in 2007. In 2008 Alison received the Wake Forest textbook chapter, and presented her work at international conferences in the fields of Institute of Regenerative Medicine Young Investigator Award in recognition of her work on modular tissue engineering. Since biomedical engineering, regenerative medicine and stem cell biology. establishing her own lab in 2009, she has received over $1.27M in research funding from the Natural Science and Engineering research council of Canada (NSERC), the Heart and Stroke Foundation of Canada, the Canadian Institute of Health Research Congratulations to Mihn and Melissa! (CIHR), the Canadian Foundation for Innovation (CFI) and University of Toronto’s Connaught fund.

46 47 TERMIS-AM AWARDS PROGRAM - 2013 AWARDEES EXIBITORS

Senior Scientist Award: Floor Plan & Booth Location William R. Wagner, PhD, Director of the McGowan Institute for Regenerative Medicine and Professor of Surgery, Bioengineering and Chemical Engineering at the University of Pittsburgh. Dr. Wagner also serves as the Deputy Director of the NSF Engineering Research Center on “Revolutionizing Metallic Exhibit Hall Hours: Biomaterials”. He holds a B.S. (Johns Hopkins Univ.) and Ph.D. (Univ. of Texas) in Chemical Engineering. Dr. Wagner is the Coordinator for the Cellular and Organ Engineering track for Bioengineering graduate students, and currently teaches in the areas of biomaterials and tissue engineering. Sunday, November 10 Professor Wagner is the Founding Editor and Editor-in-Chief of one of the leading biomaterials journals, “Acta Biomaterialia”, and currently serves on the editorial boards of the “Journal of Biomedical Materials 7:00 PM - 9:00 PM Research part A”, “Biotechnology and Bioengineering”, and the “Journal of Tissue Engineering and Regenerative Medicine”. Dr. Wagner is also a past president of the American Society for Artificial Internal Organs (ASAIO; 2010- 2011) and serves on the Executive Board of the International Federation of Artificial Organs (IFAO). He is a fellow and former vice president of the American Institute for Medical and Biological Engineering (AIMBE; 2000) and has also been elected a fellow of Monday, November 11 the Biomedical Engineering Society (2007), the International Union of Societies for Biomaterials Science and Engineering (2008) and the American Heart Association (2001). He has served as Chairman for the Gordon Research Conference on Biomaterials: 9:30 AM - 10:00 AM Biocompatibility & Tissue Engineering as well as for the First World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS). In 2006 he was selected to the “Scientific American 50”, the magazine’s annual list recognizing leaders in science and technology from the research, business and policy fields. In 2011 he was awarded the Society for 11:30 AM - 1:00 PM Biomaterials Clemson Award for Applied Research. He has served on numerous NIH and NSF study sections, is a member of the NIH College of Reviewers, and has been a member of external review committees for national and international organizations 2:30 PM - 3:00 PM focused on bioengineering and regenerative medicine. His research has generated numerous patents and patent filings that have resulted in licensing activity, the formation of a company, and University of Pittsburgh Innovator Awards in 2007, 2008, 2009 and 4:30 PM - 6:00 PM 2010.

Dr. Wagner’s research interests are generally in the area of cardiovascular engineering with projects that address medical device biocompatibility and design, tissue engineering, and targeted imaging. His research group is comprised of graduate students Tuesday, November 12 in Bioengineering and Chemical Engineering as well as post-doctoral fellows with backgrounds in surgery, polymer chemistry, or engineering. Dr. Wagner and his group enjoy working across the spectrum from in vitro to clinical studies. The McGowan 9:30 AM - 10:00 AM Institute and the University of Pittsburgh Medical Center are uniquely positioned to allow such broad-based projects to flourish and complement one another. Researchers within Dr. Wagner’s group are afforded the opportunity to observe first-hand the 11:30 AM - 1:00 PM clinical successes and failures of currently employed cardiovascular devices while concurrently working on projects that attempt to describe the current modes of failure, test solutions for the current device shortcomings, or develop technologies 2:30 PM - 5:00 PM that may find application as future cardiovascular therapies. The front-line experience afforded by the clinical environment has proven invaluable in the learning experience of group members, not to mention the input such experience has on the creative environment. AABB Center for Cellular Therapies Booth No. 4 IOP Publishing Booth No. 3 Mary Ann Liebert, Inc. Outstanding Student Award: Biomomentum Booth No. 27 Kaneka Booth No. 25 BioSpherix, Ltd. Booth Nos. 40 & 41 Lifecore Biomedical Booth No. 35 Rameshwar R. Rao, NSF Graduate Student Research Fellow, Department of Bose Corporation - ElectroForce McGowan Institute for Regenerative Biomedical Engineering at the University of Michigan Booth No. 34 Booth No. 2 Systems Group Medicine Ram Rao received his undergraduate degree in biomedical engineering from the University of California - Davis in 2008 and did undergraduate research with Dr. Kent CellScale Biomaterials Testing Booth No. 19 Nitta Gelatin Booth No. 26 Leach. As in undergraduate student he was awarded the Department of Biomedical COMECER Booth No. 28 NovaMatrix Booth No. 24 Engineering Outstanding Undergraduate Research Award and a University of California, Espin Technologies Booth No. 36 Panasonic Healthcare Company of Davis Human Corps Community Service Award. Booth No. 18 Evonik Corporation Booth No. 11 North America He then moved on to the University of Michigan for his graduate students and received Flexcell International Corp Booth No. 16 Parker H. Petit Institute for an MS and PhD in biomedical engineering in Dr. Jan Stegemann’s laboratory. His thesis Bioengineering and Bioscience at Booth No. 17 Fluidigm Booth No. 8 worked focused using cell-based therapies to engineer vascularized bone tissue. During Georgia Institute of Technology his graduate students, Ram was funded by the Tissue Engineering and Regenerative Medicine T32 Training Grant and the National Harvard Apparatus Regenerative Booth No. 32 RoosterBio / VitaCyte Booth No. 20 Science Foundation Graduate Research Fellowship. Ram was also awarded the Society for Biomaterials Award for Outstanding Technology Tissue Source Booth No. 9 Research - Ph.D. Candidate in April of this year. HypOxygen Booth No. 39 Trevigen Booth No. 33 IEEE Engineering in Medicine and Ram is now currently a medical student at the University of Michigan and serves as one of the directors of the University of Booth No. 5 Wake Forest Institute for Biology Society (EMBS) Booth No. 1 Michigan Student Run Free Clinic. Regenerative Medicine Instron Booth No. 10 48 49 EXHIBITORS EXHIBITORS

Kaneka Corp - Toward an Even More As the field regenerative therapies (CT) Harvard Apparatus Regenerative Impressive and Productive Future. Kaneka The ElectroForce Systems Division of expands, so does AABB’s commitment to Technologies is the leading supplier of Corporation is a producer of chemical NovaMatrix, a business unit of FMC Bose Corporation is a leading supplier of supporting the community of professionals. eSpin Technologies, Inc.® will be exhibiting bioreactors and control systems for the products including resins, pharmaceutical BioPolymer, provides well-characterized, mechanical testing instruments to research The AABB Center for Cellular Therapies its nanofiber based biomedical product - decellularization and cellularization of intermediaries, food supplements, synthetic ultrapure alginate, peptide coupled institutions, medical device manufacturers and (AABB CCT) is devoted to the development Cytoweb® for tissue engineering. Available hollow and Solid Organs. THE ORCA fibers and fine chemicals. The Innovative alginate, water-soluble chitosan salts engineering companies worldwide. Proprietary of programs, services and resources that with a variety of options this nanofiber material (Organ Regeneration Control and Analysis) Bone Marrow MSC Separation Device and sodium hyaluronate for use in tissue linear motor technology in Bose® test are critical to donor and patient care, is produced in clean rooms under cGMP system offers unmatched flexibility and harvests mesenchymal stem cells (MSC) engineering, cell encapsulation, drug instruments provides exceptional performance, product safety and successful outcomes. compliant conditions. Cytoweb® provides via a filter from bone marrow. delivery and medical device applications. simplicity and efficiency in sterile and non- ease of use. Physiological parameters can AABB offers accreditation for product repeatable characteristics that mimic 3D http://kaneka-cellseparation.jp/msc/english; Our new NovaMatrix 3-D cell culture sterile applications for material characterization be mimicked and all parameters recorded manufacturing and clinical administration intracellular matrixes to enhance cellular http://www.kaneka.co.jp/kaneka-e/ system expands research possibilities in and biological stimulation. in real time. www.harvardapparatus.com of novel products. Visit the AABB CCT growth. www.espintechnologies.com regenerative medicine and drug discovery. http://worldwide.bose.com/electroforce/ booth to learn more about our latest http://www.novamatrix.biz/ educational offerings in cellular and regenerative therapies and discover how you can get engaged! www.aabbcct.org Evonik is a global specialty chemicals HypOxygen provides state of the art Panasonic Healthcare Company is company and leading supplier of bioresorbable hypoxic workstations that lead the way in Do you need a source of pharmaceutical a global, leading provider of energy, polymers, amino acid derivatives, drug delivery advancing research and innovation, while grade sodium hyaluronate for your TERM environment, and lifestyle applications with technologies and API manufacturing to the providing continued reliability for optimum research? For over 25 years, our hyaluronan laboratory equipment for pharmaceutical, CellScale Biomaterials Testing -- CellScale Health Care industry. Our portfolio includes results. We specialize in low oxygen has improved the lives of more than 50 million life science and biotechnology applications. manufactures biomaterial and mechanobiology custom bioresorbable polymers for regenerative workstations and incubator equipment patients. Please visit our booth and learn more Product lines include space-efficient VIP® test systems. Our mechanical test systems are scaffolds and cell culture reagents that include for scientists focusing on cell research or contact Rebecca at ultra-low temperature freezers, cryogenic specifically designed for biomaterials testing amino and keto acids, peptides and customized applications requiring precise atmospheric [email protected] or freezers, pharmaceutical and medical and incorporate temperature-controlled media products for media development. conditions that can be accurately 952-368-6321. www.lifecore.com refrigerators, cell culture incubators, plant baths, image capture and analysis software, www.evonik.com controlled. www.hypoxygen.us growth chambers, and portable autoclaves. www.panasonic.com/biomedical Biomomentum commercializes the and a range of gripping mechanisms. Our cell Mach-1™, a mechanical tester capable culture systems enable mechanically active of performing compression, tension, environments in 2D or 3D. www.cellscale.com shear, friction, torsion, and viscosity tests for precise characterization of hydrogel, Flexcell specializes in products to apply Instron® TGT instruments are uniquely The McGowan Institute for Regenerative mechanical load, (tension, compression, fluid tissues, and soft materials. 2013 NEW designed for all aspects of tissue Medicine is a partnership between University The Parker H. Petit Institute for FEATURE: The Mach-1™ can perform shear), to cells in monolayer and 3D culture, engineering & regenerative medicine. of Pittsburgh and UPMC. It serves as a base Bioengineering and Bioscience (Petit indentation testing on curved surfaces while specifically, equipment and consumables for Comecer is a world leader in protection Test applications range from condition & for researchers and clinicians working to Institute) has revolutionized the term automatically maintaining the indenter creating environments to stretch monolayer technologies in the field of nuclear medicine, engineer developing tissues to providing advance the science of tissue engineering and “interdisciplinary research,” and has perpendicular to the surface. Biomomentum cells and 3-D constructs. www.flexcellint.com pharmaceutical isolation technology and an in vitro testbed for drugs and cell biomaterials, cellular therapies, and medical become an incubator for research teams to also offers biomechanical testing services. nuclear power plant equipment. therapy development. Instron TGT provides devices. McGowan’s mission includes the tackle complex medical research problems www.biomomentum.com www.comecer.com customers with comprehensive solutions development of innovative clinical protocols using an interdisciplinary approach. It has for all their research, quality and testing and the transfer of emerging technologies from grown to include more than 140 faculty requirements. www.instron.com “the bench to the bedside”. (www.mcgowan. members from a wide variety of disciplines, Fluidigm develops, manufactures, and markets pitt.edu) which has played a vital role in the success life science systems based on integrated fluidic of the Institute and its culture. From its circuits (IFCs). This technology furthers research eight “research neighborhoods” to the open by minimizing costs and enhancing sensitivity atrium and even the building’s artwork, the for applications such as single-cell gene Petit Institute was built from the ground up expression, high-throughput SNP genotyping, IOP Publishing is an international, to foster an environment where innovative BioSpherix will be exhibiting the Xvivo IEEE Engineering in Medicine and Biology and next-generation sequencing. Single- not-for-profit, learned society publisher. research emerges from the joint activities System, world’s first and only barrier Society (EMBS) is the world’s largest cell gene expression profiling has recently We are a leader in scientific publishing Nitta Gelatin is one of the world’s leading of bioengineering and bioscience faculty isolator optimized for cells. Economical international society of biomedical engineers emerged as a powerful method to uncover and the electronic dissemination of suppliers of gelatin and collagen related from more than nine different schools and and practical alternative to cleanrooms for and provides access to the people, practices, heterogeneity in cell populations. In response peer-reviewed research. Visit booth #3 products including beMatrix™ low-endotoxin departments. www.petitinstitute.gatech.edu cGMP compliant production of human cells information, ideas and opinions shaping one to this, Fluidigm has developed a streamlined for a copy of Biomedical Materials and gelatin. This high quality low-endotoxin for clinical use. Get better contamination of the fastest growing fields focusing on the and automated workflow for capturing and Biofabrication. http://www.iopscience.iop. gelatin has a variety of potential applications control, better process control, better development and application of engineering analyzing single cells. The new C1™ Single- org/bmm;www.iopscience.iop.org/bf in the fields of regenerative medicine, quality control, better pocketbook control. concepts and methods to provide new Cell Auto Prep System isolates single cells medical devices and scientific research and is Stop by the BioSpherix booth. solutions to biological, medical and healthcare starting with low cell number input. manufactured in a state-of-the-art biological www.biospherix.com problems. http://www.embs.org www.fluidigm.com clean room. http://nitta-gelatin.com/

50 51 EXHIBITORS TERMIS-AM 2013 SPONSORS

Organizer: Conference Sponsors:

To accomplish its mission, the Society brings together the international community of VitaCyte manufactures and sells purified persons engaged or interested The mission of the Wallace H. Coulter Department & defined tissue dissociation enzymes to in the field of tissue engineering of Biomedical Engineering at Georgia Institute of isolate or recover cells from culture. Rigorous and regenerative medicine and promotes education and research within Technology and Emory University is to shape and characterization of the purified enzymes the field of tissue engineering and regenerative medicine through regular advance the discipline of biomedical engineering through using functional enzymatic assays improves meetings, publications and other forms of communication. The Society innovative research and inspiring education, with the goal lot to lot consistency, leading to a consistently also serves as an international forum to promote the informed discussion of comprehensive integration of engineering methods into RoosterBio is focused on building a manufactured, low endotoxin product. This of challenges and therapeutic benefits of the application of tissue the mainstream of health care. http://www.bme.gatech.edu robust and sustainable Regenerative manufacturing process minimizes the need engineering and regenerative medicine technologies. Most importantly, Medicine industry. Our products are for lot testing prior to use. www.vitacyte.com the Society is committed to bringing you closer to key professionals affordable and standardized primary cells to support your mutual understanding of the field, accelerate your and media, manufactured and delivered research in the field and to enable you to contribute to the ultimate with high quality and in formats that care of patients in this very important way. To affect this interchange of simplify product development efforts. information, the Society has endorsed the journal, Tissue Engineering, as The Stem Cell Engineering Center (SCEC) was RoosterBio products will accelerate the its official publication and has negotiated a reduced subscription rate for established in 2010 to foster the growth of the stem translation of cell therapy and tissue members of the TERMIS. In addition, the TERMIS publishes a quarterly cell research community at Georgia Institute of engineering technologies into the clinic. newsletter for its members to keep them abreast of developments in the Technology. The center’s mission is to cultivate www.roosterbio.com field. The TERMIS World Congress Meeting will be held every three years. collaborative relationships between the basic sciences In the interim years the Continental Chapters will host annual meetings along with investigators from various engineering The Wake Forest Institute for to promote tissue engineering and regenerative medicine research disciplines to address key hurdles and technological Regenerative Medicine’s mission is to regionally. www.termis.org challenges currently impeding the development of improve patients’ lives through regenerative stem cell therapeutics and diagnostics. The Stem Cell medicine therapies. Its scientists engineered Engineering Center provides core facilities and services the first laboratory-grown organs to be PLATINUM CONFERENCE SPONSORS: to members of the center, such as access and training to Tissue Source provides porcine tissue implanted into humans. The team currently work with human pluripotent stem cells and advanced for tissue engineered medical devices, is working to engineer more than 30 different cytometry equipment for phenotypic analyses, to facilitate regenerative medicine technologies organs and tissues and to develop cell investigators to better integrate the use of stem cells into and biomedical research. Our QMS is therapies to restore organ function. their research programs. ISO13485:2003 and 9001:2008 certified, http://www.wakehealth.edu/wfirm/ http://www.stemcellengineering.gatech.edu ISO 22442-2:2007, FDA 21 CFR 820 and 589 compliant. The confidential The Parker H. Petit Institute for Bioengineering and Bioscience customized processing and exceptional (Petit Institute) has revolutionized the term “interdisciplinary research,” quality provided by Tissue Source are and has become an incubator for research teams to tackle complex a foundation for exceptional medical medical research problems using an interdisciplinary approach. It has products. The North American Veterinary Regenerative grown to include more than 140 faculty members from a wide variety of www.tissue-source.com Medicine Association (NAVRMA) promotes the disciplines, which has played a vital role in the success of the Institute acquisition and distribution of knowledge regarding the and its culture. From its eight “research neighborhoods” to the open emerging fields of regenerative medicine and stem cell atrium and even the building’s artwork, the Petit Institute was built therapy. These areas of medical research and their clinical from the ground up to foster an environment where innovative research applications are concerned with the regeneration of emerges from the joint activities of bioengineering and bioscience faculty damaged tissues and organs and the development of new from more than nine different schools and departments. Trevigen supplies Basement Membrane methods to help the body heal itself. www.petitinstitute.gatech.edu Extract (BME), laminin, fibronectin and http://www.navrma.org/ vitronectin to enable undifferentiated stem cell growth. Laminin and BME The National Science Foundation The Regenerative Engineering and (NSF) is an independent federal agency used in high concentrations provide a Medicine (REM) research center is a joint suitable matrix to support differentiation created by Congress in 1950 “to promote collaboration between Emory University the progress of science; to advance the of stem cells into organoid structures. and Georgia Institute of Technology. REM is national health, prosperity, and welfare; Additionally we offer a wide range of specifically focused on endogenous repair or to secure the national defense”. NSF’s extensively tested products for 3D culture how the body can harness its own potential goals--discovery, learning, research infrastructure and needs. www.trevigen.com to heal or regenerate. Bone, muscle, nerves, stewardship--provide an integrated strategy to advance the heart, blood vessels, and other tissues each frontiers of knowledge, cultivate a world-class, broadly have a baseline ability to regenerate. REM inclusive science and engineering workforce and expand investigators ask what can be done when trauma or disease in humans the scientific literacy of all citizens, build the nation’s overwhelms the ability of tissues or organs to regenerate on their own. research capability through investments in advanced http://regenerativeengineeringandmedicine.com/ instrumentation and facilities, and support excellence in science and engineering research and education through a capable and responsive organization. www.nsf.gov

52 53 TERMIS-AM 2013 SPONSORS

Additional funding for this conference was made possible by 1 R13 EB 017617-01 from the National Institute of Biomedical Imaging and Bioengineering, the National Institute for Arthritis and Musculoskeletal and Skin Diseases, and the National Institute of Dental and Craniofacial Research. The views expressed in written conference Cells Tissues Organs aims at bridging the gap materials or publications and by speakers and moderators do not necessarily between cell biology and developmental biology reflect the official policies of the Department of Health and Human Services; and the emerging fields of regenerative medicine nor does mention of trade names, commercial practices, or organizations (stem cell biology, tissue engineering, artificial imply endorsement by the U.S. Government. organs, in vitro systems and transplantation biology). CTO offers a rapid and fair peer-review and exquisite reproduction quality. http://www.karger.com/cto

Tissue Source provides porcine tissue for tissue engineered medical devices, regenerative medicine technologies and biomedical research. Our IOP Publishing is an international, not-for- QMS is ISO13485:2003 and 9001:2008 certified, ISO 22442-2:2007, FDA profit, learned society publisher. We are a 21 CFR 820 and 589 compliant. The confidential customized processing leader in scientific publishing and the electronic and exceptional quality provided by Tissue Source are a foundation for dissemination of peer-reviewed research. Visit exceptional medical products. www.tissue-source.com booth #3 for a copy of Biomedical Materials and

Biofabrication. http://www.iopscience.iop.org/ bmm;www.iopscience.iop.org/bf

The Wake Forest Institute for Regenerative Medicine’s mission is to improve patients’ lives through regenerative medicine therapies. Its scientists engineered the first laboratory-grown organs to be implanted into humans. The team currently is working to engineer more than 30 different organs and tissues and to develop cell therapies to restore organ function. http://www.wakehealth.edu/wfirm/ Tissue Engineering is the premier biomedical journal merging engineering and life sciences for tissue development. Part A provides fundamental Media sponsors: research and understanding of structure-function relationships. Part B, Reviews publishes critical discussion and analyses to assess progression in the field. Part C Methods presents procedures and protocols to translate research into future clinical applications. www.liebertpub.com/products/ product.aspx?pid=315

Science Translational Medicine promotes human health by providing a forum for communicating the latest biomedical research findings from translational researchers in all areas of medicine. The journal strives to bridge the gap between the rich foundation of basic science and the needs of clinical medicine, facilitating information exchange in both directions. www.stm.sciencemag.org/

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