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Top 50 most influential people on Stem Cells today terrapinn.com/ TOP 50 stem influencers terrapinn.com/loyaltyasia

Who are the most influential people in stemcell the global and cell field?

This is the question we asked our blog subscribers, LinkedIn group members and anyone in our contact network to compile a comprehensive list of the Top 50 as named by you.

The following 50 personalities were picked based on their career achievements whether this was groundbreaking discovery and research or innovation, funding, lifetime dedication or simply because they might have inspired others to do well. It is great to see that we have representatives from all aspects including industry, governments, philanthropy, academia and even showbiz.

Thank you to everyone who has helped us compile the list and please feel free to share it with your colleagues. blogs.terrapinn.com/ TOP 50 stem cell influencers

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No. 50

Paul Knoepfler Dr Catherine Prescott Michael Werner Associate Professor Owner Partner UC Davis School of Medicine Biolatris Holland and Knight

Cathy brings over 20 years of experience in [email protected] Werner has more than 25 years of Dr Paul Knoepfler is an Associate Professor in research, management and business within healthcare law, lobbying, policy Cell and Human Anatomy at the UC the life- and venture capital sectors. development and regulatory experience in Davis School of Medicine, where his lab studies She is the Founder Director of Biolatris Ltd., Washington. In addition to forming the stem cells and . He is also a faculty Co-founder and Director of UniverCELL Market Alliance for and member of the UC Davis Genome Center and , Chair of the UK National Stem Cell Network serving as its Executive Director, he is also a leader of the Initiative at the Advisory Committee, Director of the EESCN partner at the law firm Holland & Knight, UCD Comprehensive Cancer Center. He also Life Sciences Advisory Board member for the LLP. teaches graduate courses in stem cells and is an Worcester Polytechnic Institute (MA, USA) and instructor for the histology course at UCD School Advisory Committee member for the charity He focuses on issues affecting of Medicine. He is a cancer survivor, patient DebRA. Cathy is experienced in technology and pharmaceutical companies, researchers advocate, writer, and is currently the only assessment, market positioning, business and research institutions, health care faculty level academic blogger on stem cell development, strategic planning, raising investors, physicians, and patients with research in the world. venture funds and private investment. She is a particular expertise in regenerative recognised opinion leader within the stem cell medicine. and regenerative medicine business sector. TOP 50 stem cell influencers

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Eduardo Bravo Dr Christian Schneider Ram Mandalam Chief Executive Officer Chair President and Chief Executive TiGenix CAT, European Medicines Officer Agency Cellerant Therapeutics Mr. Bravo has more than 20 years Dr. med. Christian K Schneider is Senior Ram Mandalam, joined the company in experience in the . Medical Officer at the Danish Health and 2005. Ram was previously Executive He held several senior management Medicines Authority (formerly the Danish Director of Product Development at Geron positions at Sanofi-Aventis, including Vice Medicines Agency) since 2011. At the Corporation, where he managed the President for Latin America, a division with European Medicines Agency, he is the development and manufacturing of cell 2000 employees and sales of more than €1 Chairman of the Committee for Advanced based for treatment of billion. At Sanofi-Aventis he also held senior Therapies (CAT) since 2009, and also the degenerative diseases and cancer. Prior to positions in Marketing and Sales for Europe Chairman of the CHMP Working Party on Geron, he was Director of Developmental and he was General Manager for . Similar Biological (Biosimilar) Medicinal Research at Aastrom Biosciences, where he Prior to his tenure at Sanofi-Aventis, Mr. Products. Between September 2007 and July was responsible for the research and Bravo was for 7 years at SmithKline 2011, he was a member of the Committee for development programs involving ex vivo Beecham in sales positions both nationally Medicinal Products for Human Use (CHMP), expansion of human marrow stem and internationally. Mr. Bravo holds a co-opted for the area of Advanced Therapies cells and dendritic cells. Dr. Mandalam degree in Business Administration and an – , Cell and Tissue Therapies. received his Ph.D. in MBA (INSEAD), and is co-Chair of the from the University of Michigan. Alliance of Advanced Therapies. blogs.terrapinn.com/ TOP 50 stem cell influencers

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Dr Alan Lewis Dr Paul Laikind Susan Solomon Chief Executive Officer Chief Executive Officer Chief Executive Officer Medistem ViaCyte New York Stem Cell

Dr Lewis is currently a Management Paul K. Laikind, has over 25 years of Foundation Consultant to various specialty leadership experience in the biotechnology Susan L. Solomon is Chief Executive Officer companies. He was most and life sciences industry in San Diego. A and Co-Founder of The New York Stem Cell recently President, CEO and Chariman of serial entrepreneur, Dr. Laikind co-founded Foundation (NYSCF), a non-profit Ambit BioSciences, and previously President and held top executive positions at three San organization established in 2005 to and CEO of the Juvenile Research Diego companies that each went public accelerate cures through stem cell research. Foundation and President, CEO and Director before ultimately being acquired. These of Novocell, Inc. include Gensia Pharmaceuticals, Inc., A longtime health-care advocate, Ms. Viagene, Inc., which, like Gensia, was Solomon is a founding member and current Dr. Lewis currently serves as a Director of founded upon technology Dr. Laikind helped President of NYAMR (New Yorkers for the BioMarin Pharmaceutical, Inc., and BIOCOM. to create, and, most recently, Metabasis Advancement of Medical Research), is on the He holds a Ph.D. in pharmacology from the Therapeutics, Inc. where he served as Executive Committee for the Alliance for University of Wales in Cardiff and completed President and Chief Executive Officer Regenerative Medicine, and she has been a his postdoctoral training at Yale University. member of the Board of Directors of the Dr. Laikind holds a B.S. in from Juvenile Diabetes Research Foundation, New the University of , Davis, and a York Chapter. Ms. Solomon was also a Ph.D. in biochemistry from the University of member of the Strategic Planning Committee California, San Diego. of the Empire State Stem Cell Board. TOP 50 stem cell influencers

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Dr Gael Margolin Fred Gage Dr Jan Nolta Chief Executive Officer Professor, Laboratory of Stem Cell Program Director Gamida Cell Genetics UC Davis Salk Institute Dr Nolta is the Director of the Stem Cell Dr. Margolin is the president and CEO of Fred H. Gage, a professor in the Laboratory Program at UC Davis School of Medicine, and Gamida Cell. Prior to joining the company, of Genetics, concentrates on the adult directs the new Institute for Regenerative Dr. Margolin served as vice president of central and unexpected Cures. The current research in Dr. Nolta’s Denali Ventures LLC, where she specialized plasticity and adaptability to environmental laboratory is focused on developing in investments in pharmaceutical and stimulation that remains throughout the therapies that will use mesenchymal stem biotechnology companies. Dr. Margolin also life of all . His work may lead to cells (MSCs) to deliver factors for treating worked at Teva Pharmaceuticals, where she methods of replacing or enhancing Huntington’s disease and other disorders was responsible for new product initiatives, and spinal cord tissues lost or damaged due and injuries. Her group focuses on “bench to evaluation of investment opportunities for to Neurodegenerative disease or trauma. the bedside” research, and she has been the R&D division, and multiple drug involved in numerous clinical trials of gene development programs. Dr. Margolin holds a His work may lead to methods of replacing and cell therapy. She is scientific director of Ph.D. in Biology from the Weizmann Institute brain tissue lost to or Alzeimers the new Good Manufacturing Practice clean of Science and was a post-doctoral associate Disease and repairing spinal cordsdamaged room facility at UC Davis, where stem cells of at the Yale University School of Medicine. by trauma. He is the President-elect of the different types are being isolated or ISSCR. expanded for clinical trials. blogs.terrapinn.com/ TOP 50 stem cell influencers

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Keith Murphy Dr Robert Preti Chairman and Chief Executive Co-Founder, President and Director Read Bio Officer Read Bio CSO Institute for Regenerative Organovo Therapy Medicine, Wake Forest Keith Murphy has more than 17 years of Robert “Bob” Preti, PhD, is the co-founder, Anthony Atala, M.D., is the Director of the experience in biotechnology, including President, and Chief Scientific Officer of PCT. Wake Forest Institute for Regenerative serving in Product Strategy and Director of Following the acquisition of PCT by NeoStem Medicine, and the W.H. Boyce Professor Process Development roles at Amgen. His 10 Inc. in January 2011, he has also been and Chair of the Department of Urology at years at Amgen included four years as Global directing the development and expansion of . Operations Leader for the largest NeoStem’s cell therapy pipeline, as well as

development program in Amgen’s history, participating in setting NeoStem’s strategic Dr. Atala is a practicing surgeon and a Phase 3 osteoporosis/bone cancer drug direction. researcher in the area of regenerative denosumab. Prior to joining Amgen, Mr. Also active in the public health arena, Bob medicine. His current work focuses on Murphy played a central role at Alkermes, has served on the Stem Cell Banking growing new human cells, tissues and Inc. on the development team for their first Committee and Subcommittee of organs. approved product, Nutropin (hGH) Depot. the New York State Department of Health He holds a B.S. in chemical engineering from and on the New Jersey state Department of the Institute of Technology Health’s Blood Bank Advisory Committee, and is an alumnus of the UCLA Anderson chairing the Hematopoietic Progenitor Cell School of Management. Processing Subcommittee. TOP 50 stem cell influencers

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Jeff Jonas Michael Hunt Geoff MacKay Presiden, Regenerative Medicine President and CEO Chief Executive Officer Shire ReNeuron Geoff MacKay has served in his current After a varied career in R&D, commercial Michael Hunt was appointed Chief leadership role since December 2003. Mr. and entrepreneurial business roles, Jonas Executive Officer of ReNeuron in July 2005. MacKay provides Organogenesis with joined Shire in July 2008 as leader of the Prior to ReNeuron, he spent six years at significant global, commercial experience Speciality Pharmaceuticals (SP) Research & Biocompatibles International plc (sold to spanning the pharmaceutical and Development team. BTG plc) where he held a number of senior biotechnology sectors. financial and general management

Jonas has been closely involved with the positions. His early industrial career was Mr. MacKay has been specifically involved RM business since Shire acquired it as spent at Bunzl plc. He sits on the in the emerging field of regenerative Advanced BioHealing in June 2011. BioIndustry Association’s Cell Therapy and medicine for the last decade. He currently Regenerative Medicine Advisory serves as Chairman of the Board of In addition to his role as head of the SP R&D Committee and its Finance and Tax Directors for the Massachusetts team, he has been leading the RM R&D Advisory Committee. He is a Senior Industry Biotechnology Council (MassBio), and as team and has been a member of the RM Group member of the UK Government’s Chair of the Alliance for Regenerative leadership team. Office for Life Sciences and a member of Medicine (ARM). the UK Technology Strategy Board’s RegenMed Advisory Group. blogs.terrapinn.com/ TOP 50 stem cell influencers

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Baron John Krebs Paul Kemp Robin Smith Principal of Jesus College CEO and CSO Chairman & CEO Oxford University Intercytex Neostem

Professor Lord Krebs is Principal of Jesus Paul has been involved in commercial Dr. Robin L. Smith became the Chief College, Oxford. He is an internationally regenerative medicine for over 20 years. He Executive Officer and Chairman of the Board renowned scientist in the field of behavioural has a successful track record in virtually all of NeoStem effective June 2, 2006, after first ecology. aspects of the business from founding biotech joining the Company as Chairman of its companies, raising significant public and Advisory Board in September 2005. Dr. Smith Lord Krebs has published over 300 scientific private funding in Europe, US and Asia; brings to NeoStem expertise in business papers and has co-authored several books designing, building and operating GMP development and medicine, including her including the standard student textbook in facilities in the US and UK; designing and extensive and diversified experience serving his field. He holds 15 Honorary Degrees and operating clinical trials including extensive in executive and board capacities in medical numerous awards and medals for his interactions with the MHRA, EMA and FDA; enterprises and healthcare-based entities. scientific work. He is a Trustee of the Nuffield operating multi national, multi centre Phase I, During her tenure over the past six years as Foundation, Chairman of the UK Science and II and III studies, and finally, launching Chairman and CEO, Dr. Smith has Technology Honours Committee, and marketing and selling cell based products both successfully led the company to coamplete Chairman of the House of Lords Select in the US and UK. He is the inventor on several five acquisitions and raise over 100 million Committee for Science and Technology. He related to multiple regenerative dollars toward building a leading company in sits on the UK Climate Change Committee medicine products both in development and the emerging cell therapy industry. and chairs its Adaptation Sub-Committee. on the market and publishes and presents widely in the field. TOP 50 stem cell influencers

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Professor Silviu Itescu Devyn Smith Gil van Bokkelen Chief Executive Officer Chief Operating Officer President and CEO Mesoblast Neusentis Research Unit, Pfizer Athersys

Professor Itescu has established an Devyn Smith joined Pfizer's Neusentis Dr. Van Bokkelen has served as Chief Executive outstanding international reputation as a Research Unit in September 2011 as Chief Officer and Chairman since August 2000. Dr.

physician scientist in the fields of stem cell Operating Officer responsible for strategy and Van Bokkelen co-founded Athersys in October

biology, autoimmune diseases, organ operations for the unit and in working with the 1995 and served as Chief Executive Officer and transplantation, and heart failure. He is Neusentis Leadership Team in implementing Director since Athersys' founding. Prior to May currently an active faculty member of the key strategies. Neusentis is focused on 2006, he also served as Athersys' President. University of Melbourne and Monash developing assets for pain and sensory University and was previously a faculty disorders as well as developing the Dr. Van Bokkelen is the current Chairman of member of Columbia University in New Regenerative Medicine portfolio. the Alliance for Regenerative Medicine, a York. Professor Itescu has consulted for Washington D.C. based consortium of various international pharmaceutical Smith received his Ph.D. in Genetics from companies, patient advocacy groups, disease companies, has been an adviser to where his research foundations, and clinical and research biotechnology and health care investor culminated in 12 publications in leading institutions that are committed to the groups, and has served on the Board of journals such as Cell, Nature, and advancement of the field of regenerative Directors of a number of publicly-listed life Development. He also holds an M.S. in Biology medicine. He is also the Chairman of the Board sciences companies. from Idaho State University and a B.S. in of Governors for the National Center for from Brigham Young University Regenerative Medicine. blogs.terrapinn.com/ TOP 50 stem cell influencers

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Leanna Caron Christopher Calhoun Kristin Comella Vice President, and General Chief Executive Officer Chief Scientific Officer Manager, Cell Therapy and Cytori Therapeutics Bioheart

Regenerative Medicine Christopher J. Calhoun is a co-founder of Kristin Comella has over 14 years experience Sanofi-Genzyme Cytori Therapeutics and has served as the in corporate entities with expertise in Company's Chief Executive Officer, Vice- regenerative medicine, training and Leanna is a healthcare executive with 17 Chairman and Director of the Board since education, research, product development years of global marketing and business 1997. He previously served as President from and senior management. She has more than management experience. 1996 through 1998. Mr. Calhoun is the co- 12 years of cell culturing experience She is currently Vice President and General inventor on multiple U.S. and International including building and managing the stem Manager at Genzyme, a Sanofi company, patents for medical devices and implant cell laboratory at Tulane University's Center overseeing the global commercial instrumentation. Mr. Calhoun was also for and developing stem cell operations for the Cell Therapy & involved in research and management for the therapies for at Osiris Regenerative Medicine business. Plastic Surgery Bone Histology and Therapeutics. She has been a member of the While at Genzyme, Leanna has held senior Histometry Laboratory at the University of Bioheart senior management team since positions in the , , and California, San Diego. Mr. Calhoun is a co- 2004 and is currently serving as its Chief Europe. founder and Chairman of the Board of Scientific Officer. Leonardo MD, and has previously served on She currently serves on multiple boards in the Board of Directors of StemSource, Inc. the stem cell arena. TOP 50 stem cell influencers

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Robert Deans Bernard Siegel Robert Klein Executive Vice President, RM Founder and Executive Director Chair Emeritus Athersys Genetics Policy Institute California Institute for

Dr. Deans has served as the Executive Vice Bernard Siegel is the founder and full-time Regenerative Medicine President since 2011. Dr. Deans has led executive director of the nonprofit In 2003, Bob was the author of California's Athersys’ regenerative medicine research Genetics Policy Institute (GPI) based in Proposition 71, the $6 billion "California Stem and development activities since February Wellington, (Palm Beach County) Florida. Cell Research and Cures" ballot initiative. The 2003, initially as Vice President of objective of Proposition 71 was to finance $3 Regenerative Medicine, until he was Mr Siegel serves on the board of directors billion in the form of Treasury bills issued by named Senior Vice President of of the Coalition for Advancement of the State of California to support the Regenerative Medicine in June 2006, and Medical Research and Americans for Cures research on stem cells and $3 billion to cover Executive Vice President in June 2011. Dr. Foundation. He also serves on the the interest for 35 years - a total of $6 billion. Deans is highly regarded as an expert in executive committee of the Alliance for For the first 7 years of its existence, Mr. Klein stem cell therapeutics, with over fifteen Regenerative Medicine and chaired that served as the Chairman of the Governing years of experience in this field. group’s nominating committee. He is a past Board of the CIRM established by Proposition co-chair of the Governmental Affairs 71 to manage the research funds and the Committee of the International Society for peer review, standards, and grant process for Stem Cell Research. the $3 billion in stem cell research funding authorised by the Initiative. Hewas elected Chairman Emeritus on June 23rd, 2011. blogs.terrapinn.com/ TOP 50 stem cell influencers

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Ronnda Bartel Zami Aberman Martin McGlynn Chief Scientific Officer Chairman and Chief Executive President & Chief Executive Aastrom Biosciences Officer Officer

Ronnda joined Aastrom in 2006 and is Pluristem StemCells, Inc responsible for the scientific direction of the Mr. Aberman Chairman & CEO joined Martin McGlynn joined StemCells, Inc. in company, including research, development Pluristem in September 2005 and changed January of 2001 as President and Chief and technical operations. She has more than the Company’s strategy towards cellular Executive Officer and was elected to our Board 20 years of research and product therapeutics. Mr. Aberman’s vision to use of Directors on February 6, 2001. Mr. McGlynn development experience. the maternal section of the has spent several decades in the life sciences (Decidua) as a source for cell therapy, industry in Europe, Canada and the United Ronnda holds a PhD in biochemistry from the combined with Pluristem’s 3D culturing States. He began his career with Becton University of Kansas, has completed technology, led to the development of Dickinson, Ireland Ltd., and spent eight years in postdoctoral work at the University of company unique products. manufacturing operations. Michigan and received a BA in chemistry and biology from Tabor College. Mr. Aberman has 20 years of experience in He is a former member of the Board of marketing and management in the high Directors of the Confederation of Irish technology industry. He has held positions of Industries (CII) and the Pharmaceutical Chief Executive Officer and Chairman in Manufacturers Association of Canada (PMAC), , the USA, Europe, and Korea. and currently serves as a member of the Board of the Alliance for Regenerative Medicine. TOP 50 stem cell influencers

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Keith Thompson Stephen Minger Richard Garr Chief Executive Officer Global Director of R&D, Cell Director and Chief Executive Catapult Cell Therapy Centre (TSB) Technologies, GE Healthcare Officer GE Healthcare Neuralstem Keith Thompson was appointed Chief Executive of the Cell Therapy Catapult, part Dr. Orin Levine is Director of stem cell Richard Garr, JD, has been a director and of a Technology Strategy Board initiative to Delivery at the Bill and Melinda Gates our Chief Executive Officer since 1996. Mr. improve UK economic capability by bridging Foundation, where he leads the Foundation’s Garr was previously an attorney with Beli, the gap between academic invention and efforts to accelerate the introduction of new Weil & Jacobs, the B&G Companies, and commercialisation, in May 2012. Mr stem cells and related technologies and to Circle Management Companies. Mr. Garr is Thompson joined the Catapult from the improve routine immunization systems. He is a graduate of Drew University (1976) and Scottish National Blood Transfusion Service the Foundation’s focal point for engagement the Columbus School of Law, The Catholic where he was National Director, focusing on with the GAVI Alliance, whose mission is University of America (1979). Additionally, modernising the blood supply, and saving children’s lives by increasing access to he was a founder and current Board expanding the service into cell therapy. Prior immunization in poor countries. member of the First Star Foundation, a to this Mr Thompson held various senior Before that he was Executive Director of IVAC children's charity focused on abused domestic and international positions where and Professor of International Health at the children's issues; a founder of The Starlight he grew several biomanufacturing businesses Johns Hopkins Bloomberg School of Public Foundation Mid Atlantic chapter, which to become global players. Health. focuses on helping seriously ill children. blogs.terrapinn.com/ TOP 50 stem cell influencers

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No. 50

Gregory Bonfiglio Randall Mills Thomas Okarma Managing Partner President and CEO Chief Executive Officer Proteus Venture Partners Osiris Therapeutics BioTime Acquisition Corp.

Mr Bonfiglio is the Founder & Managing Dr Mills is also a member of the Board of Chief Executive Officer of BioTime Partner of Proteus, LLC – an investment Directors. Osiris Therapeutics, Inc. Acquisition Corporation, is an internationally and advisory firm focused solely on currently has two product candidates in recognized biotechnology executive and regenerative medicine. Proteus provides clinical trials for a number of indications. industry pioneer, and is acknowledged as a fund management, consulting, and Prochymal, an intravenously administered preeminent spokesman for stem cell – based investment banking services to the formulation of mesenchymal stem cells, is therapeutics and regenerative medicine. regenerative medicine industry. Proteus being evaluated in Phase 3 clinical trials Serving as the President and Chief Executive works with RM companies across all for several indications, including acute Officer of for 12 years, he stages of development from early stage to graft versus host disease (GvHD) and also managed the development of Geron’s human large pharma, as well as governmental Crohn's disease. It is the only stem cell program from inception entities pursuing RM initiatives.. therapeutic currently designated by FDA to the initiation of the world’s first FDA- as both an Orphan Drug and Fast Track authorized hESC human clinical trial in spinal product. cord injury – a milestone in the . TOP 50 stem cell influencers

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Brock Reeve Sir , Distinguished Dr Mahendra Rao Executive Director Group Leader, Director, Centre for Harvard Stem Cell Institute Wellcome Trust/CRUK Gurdon Regenerative Medicine Institute in Cambridge NIH Brock Reeve, a graduate of Yale and the Harvard Business School, is Executive Sir John Bertrand Gurdon is a British Dr Rao is internationally renowned for his Director of the Harvard Stem Cell Institute. development Biologist. He is best known for research involving human embryonic In partnership with the Faculty Directors, he his pioneering research in nuclear stem cells (hESCs) and other stem has overall responsibility for the operations transplantation and . He was cells. He has worked in the stem cell field and strategy of the institute whose mission awarded the Laskar Award in 2009. for more than 20 years, with stints in is to use stem cells, both as tools and as academia, government and regulatory therapies, to understand and treat the root In 2012, he and were affairs and industry. Most recently, he causes of leading degenerative diseases. awarded the Novel Prize for Physiology or returned in August 2011 to the National Medicine for the discovery that mature cells Institutes of Health (NIH), as Director of can be converted to stem cells. His Nobel the new NIH Center for Regenerative Lecture was called "The Egg and the Nucleus: Medicine (NIH CRM). He co-founded Q A Battle for Supremacy". Therapeutics, a company based in Salt Lake City. blogs.terrapinn.com/ TOP 50 stem cell influencers

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Michael West Alan Trounson, Arnold Caplan Chief Executive Officer President Chief Scientific Officer BioTime Californian Institute for OrthoCyte Corp. Regenerative Medicine Dr West, became Chief Executive Officer Arnold Caplan, has been Chief Scientific during October 2007, and has served on Prior to joining CIRM in January 2008, Officer of OrthoCyte Corporation, a the Board of Directors since 2002. Prior to Trounson Dr Trounson founded the subsidiary of BioTime, Inc., since June 2010. becoming our Chief Executive Officer, Dr. National Biotechnology Centre of Dr Caplan is a Professor of Biology & West served as Chief Executive Officer, Excellence – ‘Australian Stem Cell Centre’. General Medical Sciences (Oncology), President, and Chief Scientific Officer of He has been a pioneer of human Director of Cellular and Molecular Basis for Advanced Cell Technology, Inc., a fertilisation (IVF) and associated the Aging Training Program of Case company engaged in developing human reproductive technologies; the diagnosis Western Reserve University in Cleveland, stem cell technology for use in of inherited genetic disease in pre- Ohio, and serves as its Director of the regenerative medicine. Dr West also implantation ; the discovery and Skeletal Research Center. Dr. Caplan co- founded Geron Corporation of Menlo production of human embryonic stem founded Cell Targeting Inc., founded and Park, California. cells and of their ability to be directed into served as President of Skeletech, Inc., and neurones, prostate tissue and respiratory served as Chief Scientific Officer and tissue. founder of Osiris Therapeutics, Inc. TOP 50 stem cell influencers

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Dr Douglas Melton terrapinn.com/loyaltyasia Investigator of the Howard Hughes 5 Medical Institute

Harvard University Department of stemcell Stem Cell and Regenerative Biology

Doug Melton is co-founding director of the Harvard Stem Cell Institute (HSCI), a leading stem cell and regenerative biologist, and one of the driving forces behind Harvard's ascendency to world leadership in the field.

Dr Melton is an Investigator of the Howard Hughes Medical Institute and the Thomas Dudley Cabot Professor in the Natural Sciences at .

Dr Melton earned a bachelor's degree in biology from the University of Illinois and then went to Cambridge University in England as a Marshall Scholar. He earned a B.A. in history and philosophy of science at Cambridge and remained there to earn a Ph.D. in at Trinity College and the MRC Laboratory of Molecular Biology.

Dr Melton serves on the Scientific Advisory Board of the Genetics Policy Institute, holds membership in the National Academy of Science and is a founding member of the International Society for Stem Cell Research. blogs.terrapinn.com/ TOP 50 stem cell influencers

Dr terrapinn.com/loyaltyasia Chief Scientific Officer

4 Advanced Cell Technology totalbiopharma

Robert Lanza, is currently Chief Scientific Officer at Advanced Cell Technology. He has hundreds of publications and inventions, and over 30 scientific books: among them, “Principles of ” and “Essentials of Stem Cell Biology,” which are recognised as the

definitive references in the field.

Dr Robert Lanza joined ACT in 1999 and has over 30 years of research and industrial experience in the area of stem cells and regenerative medicine. He is currently an Adjunct Professor at the Institute for Regenerative Medicine at Wake Forest University School of Medicine. He has several hundred of publications and inventions, and over two dozen scientific books: among them, “Essentials of Stem Cell Biology” and “Principles of Tissue Engineering” which are recognized as the definitive references in the field. Others include “Principles of Regenerative Medicine” and “One World: The Health & Survival of the Human Species in the 21st Century” (as editor, with forewords by C. Everett Koop and former President Jimmy Carter).

If all goes to plan for ACT and Dr Lanza, 2013 should see the first human trial of “rewound” cells. These are produced by turning adult cells back to a stem cell state and then coaxing them into becoming another type of cell. It will mark a milestone in the ability to generate new tissue – and maybe whole organs – from people’s own cells. TOP 50 stem cell influencers

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Prof. Chris Mason terrapinn.com/loyaltyasia Stem Cell & Regenerative Medicine 3 Bioprocessing Unit, ACBE

University College London stemcell

Professor Chris Mason is internationally recognised to be at the forefront of

the emerging fields of cell therapy and regenerative medicine translation and commercialization. A background in basic science, clinical medicine, bioprocessing and business allows Chris a unique insight and understanding of the challenges facing the cell-based therapy sector as it grows into a competitive and sustainable global healthcare industry.

Chris holds a Clinical Sciences degree from Imperial College London, a Medical degree from the United Medical and Dental Schools of Guy’s and St. Thomas’s Hospitals (now King’s College London) and a PhD under the supervision of Prof. Peter Dunnill in tissue-engineering bioprocessing from University College London.

Chris is on a number of national and international committees, working groups and initiatives related to the academic, clinical and commercial advancement of cell-based therapies and tissue engineering including; Chair of the BIA Cell Therapy & Regenerative Medicine Industry Group and member of the ISSCR Industry Committee, the Alliance for Regenerative Medicine (ARM) Communication & Education Committee and ISCT Commercialization Committee. In May 2012, he became the first President of The Regenerative Medicine Coalition. He is a Senior Partner at Proteus Venture Partners, has a broad range of expertise in commercial consultancy and is on the Scientific Advisory Boards of a number of companies. blogs.terrapinn.com/ TOP 50 stem cell influencers

Dr James Thomson terrapinn.com/loyaltyasia American Developmental Biologist 2 and Founder and Chief Scientific

Officer totalbiopharma Cellular Dynamics International

James Alexander Thomson is an American development biologist best known for deriving the first human embryonic stem cell (SC) line in 1998 and for deriving human induced pluripotent stem (iPS) cells in 2007.

He serves as Director of Regenerative Biology at the Morgridge Institute for Research in Madison, Wisconsin, is a professor in the Department of Cell and Regenerative Biology at the University of Wisconsin School of Medicine and Public Health and a professor in the Molecular, Cellular, and Department at the University of California, Santa Barbara. He is also a founder and Chief Scientific Officer for Cellular Dynamics International, a Madison-based company producing derivatives of human induced pluripotent stem cells for drug discovery and toxicity testing.

Thomson is a member of the National Acadamy of Sciences and the recipient of numerous awards and prizes. He was on the cover of TIME Magazine's "America's Best in Science & Medicine" feature in 2001 for his work with human embryonic stem cells,[and again in 2008 when the magazine named him one of the world's 100 most influential people for his derivation of human induced pluripotent stem cells.[12]

In 2011, Thomson was co-recipient, with Dr Shinya Yamanaka, of the King Faisal International Prize and the Albany Medical Center Prize. TOP 50 stem cell influencers

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Dr Shinya Yamanaka terrapinn.com/loyaltyasia Director, Center for iPS Cell Research and Application, 1 Professor

Institute for Frontier Medical Sciences, Kyoto University stemcell

Dr Shinya Yamanaka is a Japanese physician and researcher of adult stem cells. He serves as the director of Center for iPS Cell Research and Application and a professor at the Institute for Frontier Medical Sciences at Kyoto University. ; as a senior investigator at the UCSF-affiliated J David Gladstone Institutes in San Francisco, California; and as a professor of anatomy at University of California, San Francisos UCSF). Yamanaka is also the current president of the International Society for Stem Cell Research (ISSCR).

He received the Wolf Prize in Medicine in 2011 with , the Milennium Technology Prize in 2012 together with Linus Torvalds.

In 2012 he and John Gurdon were awarded the Novel Prize for Physiology or Medicine for the discovery that mature cells can be converted to stem cells.

In 2013 he was awarded the $3 million Breakthrough Prize in Lifesciences for his work.

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Over 60% of our attendees come from the World’s leading pharma, biotechs and academia.

Combining a high level conference with a focused exhibition and adding in guaranteed meetings with targeted buyers in a 1-2-1 partnering format makes this event the one must-attend event for the whole stem cell market.

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