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Celebrating Prof. Edwards’ Receiving the Nobel Prize 16th World Congress on In Vitro Fertilization 6th World Congress on In Vitro Maturation September 10-13, 2011 Tokyo, Japan Final Program and Abstracts International Society for In Vitro Fertilization with the cooperation of The Japan Society of Fertilization and Implantation Congress President: Osamu Kato (Director, Kato Ladies Clinic) Congress Vice-President: Hisao Osada (Former Professor, Nihon University) TABLE OF CONTENTS ■FINAL PROGRAM 3 Welcome Messages 7 Committees 9 Congress Information 10 Date and Venue, Contacts, Registration, Message Board, Poster Area 11 Commercial Exhibition, Lunch and Coffee 12 Instructions for Speakers and Chairpersons 14 Instructions for Poster Presenters 15 Floor Plan of the Congress Venue 16 Social Program and Travel Desks 18 Map of the Congress Venue 19 Access to the Congress Venue 20 Airport Limousine Bus Time Table 21 Local Information 27 Agenda-at-a-Glance 31 Announcement of the 17th World Congress on In Vitro Fertilization, Tunis, Tunisia 2013 32 Scientific Program 33 1. Special Guest Lecture 33 2. Opening Ceremony, Opening Lecture and Welcome Reception 33 3. Plenary Lectures 34 4. Pre-Congress Workshops 35 5. Concurrent Symposia 44 6. STGO Session 45 7. ISF Session 45 8. APART Session 46 9. Oral Communications 51 10. Poster Presentations 60 11. Luncheon Seminars ■ABSTRACTS 62 Special Guest Lecture 65 Pre-Congress Workshops 75 Plenary Lectures 90 Concurrent Symposia 219 Society Sessions 238 Oral Communications 260 Poster Presentations 305 Author Index 306 Special Guest Lecture, Pre-Congress Workshops, Plenary Lectures, Concurrent Symposia 309 Oral Communications and Poster Presentations ■CERTIFICATE 317 Certificate of Attendance (Copy) 2 WELCOME MESSAGES WELCOME MESSAGE FROM THE PRESIDENT OF ISIVF Dear Colleagues, The 16th World Congress on In Vitro Fertilization (IVF), which will be held in Tokyo Japan in September 2011, is the main International Meeting of the year focusing on IVF and Assisted Reproductive Technologies (ART). With the rapid advances that continue to be achieved in these fields, this congress will constitute an important and unique multidisciplinary forum for the exchange of knowledge and the development of new ideas between the clinicians, basic and clinical scientists, embryologists and allied health professionals, that it brings together. The congress is being held in the exciting, dynamic, progressive yet traditional city of Tokyo. Come and enjoy the congress and all of the historic, cultural, artistic and culinary delights that this most welcoming and unique city has to offer. I would like to warmly thank the Japanese team and especially Dr Hisao Osada who has organized the 16th World Congress on IVF despite great difficulties related to the recent tsunami and its dramatic consequences. All the speakers have agreed to come and the participants will be numerous both because of the quality of the scientific program and also to show our solidarity. I wish you a wonderful Congress and a memorable stay in Tokyo. René FRYDMAN President, International Society for In Vitro Fertilization ABOUT ISIVF ISIVF‟s primary mission is to promote research and clinical development of in vitro fertilization (IVF) of human oocytes for the treatment of infertility and as an Assisted Reproductive Technology. Objectives include: 1. Promulgating ethical practice and standards of practice of IVF treatment; 2. Fostering collaboration between the various centers in the world that offer IVF treatment; 3. Organizing symposia for the purposes of presentation, discussion, exchange and publication of research, data, knowledge, theories and standards pertaining to IVF, and specially, a forum under the name “World Congress on In Vitro Fertilization”. 3 WELCOME MESSAGES WELCOME MESSAGE FROM THE VICE-PRESIDENT OF ISIVF Dear Colleagues, It is with great pleasure that I welcome you to this 16th World Congress of In Vitro Fertilization and to one of the world‟s most interesting and exciting cities: Tokyo. This congress celebrates Professor Robert G Edwards and his great accomplishments for which he has been awarded the Nobel Prize. This prestigious award honors him; it also honors the whole field of reproductive medicine which has been transformed by him. Holding the Congress such a short time after the devastating earthquake and tsunami, Japan experienced, is a testimony to the resilience of the Japanese people and the strong commitment and hard work of the local organization headed by the President and Vice president of the Congress Dr. Osamu Kato and Prof. Hisao Osada. I thank them personally and on behalf of the International Society for In Vitro Fertilization. I trust that you will enjoy the rich and interesting academic and social program the congress offers. I also hope that you will take the opportunity to enjoy Tokyo and other parts of Japan, and its unique and exquisite art and culture. Victor GOMEL Vice-President, International Society for In Vitro Fertilization 4 WELCOME MESSAGES WELCOME MESSAGE FROM THE PRESIDENT OF IVM Dear Colleagues, I am pleased to welcome you to the 6th World Congress on IVM and to Tokyo. On behalf of the International Society of In-Vitro Maturation (ISIVM), I extend our sincere condolences to the Japanese people for the terrible losses and suffering they have recently incurred. Their bravery and resilience in the face of unspeakable tragedy have been a remarkable testament to human dignity and endurance. This meeting marks a special event in the history of reproductive medicine: the presentation of the 2010 Nobel Prize in Physiology or Medicine to Professor Robert Edwards. On a personal note, Professor Edwards has played a very special role in my life as a cherished mentor and, along with Howard Jacobs and Stuart Campbell, as a partner in the London Women's Clinic. I am grateful and privileged to have worked with him and deeply appreciate the formative role he played in my career. This well-deserved honor took more than 30 years in coming, but I believe it reflects a recognition of the growing importance of reproductive medicine. Following the birth of the first IVF baby through the pioneering achievements of Professor Edwards, as well as his early work in in-vitro maturation (IVM), ART has advanced by leaps and bounds over the past three decades. The advent of IVM heralded a simpler form of treatment without the need for expensive fertility drugs that could also have unpleasant and potentially dangerous side effects. However, because of its initially poor pregnancy rates, it has been slow to gain acceptance. But as clinical pregnancy rates/cycle started approach 50% in the best centres internationally, IVM is rapidly growing in importance as a viable treatment. It is an attractive option for patients at high risk of ovarian hyperstimulation syndrome, those who have had recurrent unexplained IVF failures, and those who have had poor or hyper responses to IVF. IVM, followed by oocyte vitrification, also gives cancer patients, and those with other conditions such as severe SLE, the option of preserving their fertility without the need for contraindicated gonadotropin stimulation before they undergo oocyte retrieval and oocyte vitrification. In Montreal, our team has preserved fertility of over 200 women with various medical conditions and in a medical trial achieved a live-birth rate of 20%/cycle through IVM/oocyte vitrification and reported the birth of the first four healthy babies. By attending this meeting, you will have the opportunity to learn about the latest advances in IVM and its value as a complementary treatment to IVF. As more and more centres provide IVM as an option to their patients, the ISIVM believes it is essential to establish an international registry to track success rates, pregnancy outcomes, and the health of newborn babies. This major initiative is important to all ART practitioners and I urge you to join us to make your voice heard. The benefits of membership are fully explained at our website, www.isivm.com. I hope you enjoy the Congress and your time in the unique and exciting city of Tokyo. Seang Lin Tan President, International Society for In Vitro Maturation 5 WELCOME MESSAGES WELCOME MESSAGE FROM THE CONGRESS PRESIDENT AND THE CONGRESS VICE-PRESIDENT Dear Colleagues, Ladies and Gentlemen, Osamu Kato Hisao Osada It is our great pleasure to welcome you all to the 16th World Congress on In Vitro Fertilization. Over the past decade and a half, the World Congress on In Vitro Fertilization has established itself as one of the most significant international gatherings for all doctors and scientists who are working in the field of reproductive health. Inviting more than 1000 health professionals, including clinicians, scientists, embryologists and professionals working in allied fields, the Congress is a vital forum for the exchange of cutting-edge information in this rapidly advancing field. We have been preparing to hold this prestigious congress for years and have been really looking forward to welcoming you. In the midst of our preparation, though, the devastating earthquake struck the Tohoku District of Japan on March 11, 2011, and as a result it nearly became impossible for us to hold this congress. However, our friends all over the world have extended their kind support to us and our fellow countrymen and women and thanks to you all, we are now able to hold the congress as planned here in Tokyo. For your unflinching support, we would like to express our deepest gratitude. Before this trying experience, however, we had been thrilled to receive a wonderful piece of news - the presentation of the 2010 Nobel Prize in Physiology or Medicine to Professor Robert Edwards, the patron of the International Society for In Vitro Fertilization. We ourselves remember well the time he made a visit to our clinic in Tokyo. We are very happy and honoured to have a chance to review and celebrate his achievements in the Opening Ceremony of this Congress.
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