International Journal of Molecular Sciences Article Interaction of Mycotoxin Alternariol with Serum Albumin Eszter Fliszár-Nyúl 1,2, Beáta Lemli 2,3,Sándor Kunsági-Máté 2,4, Luca Dellafiora 5 , Chiara Dall’Asta 5, Gabriele Cruciani 6,Gábor Peth˝o 1,7 and Miklós Poór 1,2,* 1 Department of Pharmacology, Faculty of Pharmacy, University of Pécs, Szigeti út 12, H-7642 Pécs; Hungary;
[email protected] (E.F.-N.);
[email protected] (G.P.) 2 János Szentágothai Research Centre, University of Pécs, Ifjúság útja 20, H-7642 Pécs; Hungary;
[email protected] (B.L.);
[email protected] (S.K.-M.) 3 Institute of Organic and Medicinal Chemistry, Medical School, University of Pécs, Szigeti út 12, H-7624 Pécs, Hungary 4 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Pécs, Rókus utca 2, H-7642 Pécs, Hungary 5 Department of Food and Drug, University of Parma, Via G.P. 7 Usberti 17/A, 43124 Parma, Italy; luca.dellafi
[email protected] (L.D.);
[email protected] (C.D.) 6 Department of Chemistry, Biology and Biotechnology, University of Perugia, Via Elce di Sotto 8, 06123 Perugia, Italy;
[email protected] 7 Department of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, Szigeti út 12, H-7624 Pécs, Hungary * Correspondence:
[email protected]; Tel.: +3672-536-000 (ext. 35052) Received: 19 April 2019; Accepted: 8 May 2019; Published: 12 May 2019 Abstract: Alternariol (AOH) is a mycotoxin produced by Alternaria species. In vitro studies suggest the genotoxic, mutagenic, and endocrine disruptor effects of AOH, and an increased incidence of esophageal cancer has been reported related to higher AOH exposure.