GENOTYPING AND GENE EXPRESSION SOLUTIONS From Single Service Modules To Fully Integrated Projects.

Microsatellites

SNPs DNA Extraction Marker Discovery Expression Analysis qPCR INDELs Genotyping Transcriptome Analysis Sequencing based Genotyping Residual DNA Testing Illumina Affymetrix Fluidigm Cell Line Authenticity DNA Quantification Assay Design & Validation

eurofinsgenomics.com 2014_0110/03_2014/2.500 Genotyping Services – Innovation & Expertise.

Benefit from our unique technological portfolio, our experience in applied genetic testing and our global laboratory network! Discover our large selection of state-of-the-art service platforms. Combine our services according to your needs and applications.

De-Novo DNA marker discovery by DNA Profiling of Humans and Animals Next Generation Sequencing With Eurofins Forensics we have Germany’s largest We can help you find new SNPs for all species from virus to commercial provider for DNA forensics in house, working plant, with or without a reference sequence. Ask us for the mainly for police and criminal investigators, offering human best solution to reduce your genome of interest complexity! DNA profiling from scene of crime samples or thousands of buccal swabs in mass screenings. Animal profiling is used Genome-wide SNP Genotyping by for forensic as well as animal breeding purposes. Next Generation Sequencing Cell Line Authenticity Service Various technologies are available to genotype species where no genome sequence is available. Discuss your Profit from our DNA profiling experience in forensics! needs with us. We will find a solution. We provide full cell line authenticity services from DNA extraction to DNA profiling. We issue official certificates Genome-wide SNP Genotyping by Microarrays of authenticity to you that are accepted by peer reviewed scientific journals. As a Certified Service Provider of Illumina since 2007 and Authorised Service Provider of Affymetrix since 2004 Fragment Length Analysis Services our array genotyping service stands for highest available quality, fast turnaround times and long-term experience. We can help you design your microsatellite / STR analysis We analyse standard arrays for human, animal and plant project. Depending on your lab capabilities we either SNP genotyping as well as customised array solutions for perform the capillary electrophoresis (CE) only or the whole all species up to 384-sample arrays. fragment length analysis project from DNA extraction, primer design and production, assay set-up, PCR and CE Gene-wide / Individual Marker Genotyping for you.

We are happy to help you in validating your data, Agrigenomics Services fine-mapping a candidate region or determining the individual’s genotype at a specific mutation. We are supporting plant and animal We will recommend the best technology, depending on breeders with our superior technical the specific project requirements: Roche LightCycler sequencing, genotyping equipment based real-time PCR assays, Fluidigm BioMark, Sequenom and our scalable capacities. We have MassArray, Sanger sequencing et cetera. a deep understanding of agrigenomic relevant questions and what our breeding DNA Extraction customers need. We are proud to have this unique combination: best equipped genomic We can extract high-quality DNA from your samples: service laboratories and applied agricultural body fluids, tissue, soil, plant material, faeces, hair expertise in-house and also in our Eurofins Agroscience follicles, buccal swabs et cetera. We use commercially department. Meet us and experience our outstanding available extraction kits (manually or automatically) with agrigenomics service for large and small projects. subsequent DNA quality check. Pharmacogenomics Services Consultation and Project Management Comprehensive services are available for individual study We will find the perfect solution for you by integrating the or project needs from preclinical phase throughout all latest technologies for sequencing and genotyping. One of phases of clinical trials. Benefit from our professional our in-house experts will be assigned to be your project GLP / GCP compliant project management together with manager to provide a flexible, competent service with scientifically well-founded consultancy by our in-house global reach, high industry standards and scalable capacity. experts. eurofinsgenomics.com http://dms.int.eurofins.local/mk/HighResFiles/Agriculture/Young%20 maize_2023x2430px.jpg Gene Expression Services.

The entire range of gene expression services is available to you - from single target to whole transcriptome analysis. Our choice of quantitative PCR, next generation sequencing as well as microarray methods will be targeted for your research or industrial project.

Transcriptome Analysis by Next Generation Sequencing Target Gene Expression Service

With our expert knowledge and proprietary protocols for Eurofins Genomics covers all steps in quantitative PCR NGS we are happy to help you in de novo transcriptome (qPCR) – from the development of the experimental sequencing or NGS based expression profiling for many strategy to the final data analysis. We use validated or species. Find more details in our NGS brochure or contact us. customised probes or SYBR Green assays. Depending on the project we select the best suitable platform, for Transcriptome Analysis by Expression Arrays example Roche LightCycler or Fluidigm BioMark.

As a Certified Service Provider of Illumina since 2007 and Authorized Service Provider of Affymetrix since 2004 our expression array service delivers highest available quality and fast turnaround times. We analyse standard Affymetrix cartridge and peg-arrays for human, animals, plants and organisms and Illumina expression arrays. Discuss your project with us and we will help you select the right array. RNA Extraction miRNA Analysis We offer you the possibility to gain high-quality RNA from a variety of resources, extracted Small molecules – large impact. Our miRNA testing service manually or automatically and with a subsequent quality comprises the analysis by microarrays, NGS or qPCR. check. Depending on the number of samples and the Discuss your project with us and we help you in selecting further analysis we will recommend you the sampling the best technology. strategy and help you to get the best out of your samples.

DNA Quantification Services.

Residual DNA Testing qPCR Assay Design and Validation

We have broad experience in the detection of residual DNA Profit from our unique combination: we are best in primer in biopharmaceutical and other biotechnical products. We production and gene synthesis and have broad experience detect and quantify the residual nucleic acids by qPCR in the qPCR analysis for various applications. We design from various production stages and from traces to large your qPCR assays and validate according to international contaminations. guidelines.

Food and Environment DNA Testing Consultation and Project Management

We are the DNA competence centre for the international Discuss your gene expression or DNA quantification Eurofins network, with more than 190 laboratories. We needs with us. We will find the perfect solution for you routinely analyse a wide range of samples to determine by integrating the latest technologies and regulations. the species and to quantify DNA contamination of foreign Highest standards (up to GLP / GCP compliance) and well species in the products. We strictly work according to trained in-house experts who focus on your project will validated and accredited methods that are documented in satisfy each demand. standard operation procedures. Experience The Power Of DNA. Your UpcomingProject? Why ChooseEurofinsGenomicsFor eurofinsgenomics.com please havealook onourwebsite:eurofinsgenomics.com To contactEurofinsGenomics‘headquarters inUSA,JapanIndiaortolocatea distributor inyourarea, Feel freetocontactusviaemail andamemberofourcustomersupportteamwillbehappy toassistyou. 8 a.m.–6p.m.CET Official businesshours: +49 80928289-77 Phone: [email protected] Email: need it.Findyourcustomerservicecontactnumberaccording toyourcountrybelow: Our missionistodeliverfirstclassproductstogetherwithprofessional, fastandcompetentcustomersupportwheneveryou A Word ForUs. Service IsMoreThanJust including therequirementsofISO13485(medicaldevices Our QM/QA-SystemiscertifiedaccordingtoISO9001, Quality Management applications, testing,analysisandresearch. of-the-art technologyfromallareasrelatedtoDNA Eurofins Genomics‘EuropeansiteinGermanyusesstate- Combined Expertise and researchapplicationsworldwide. pharma, diagnostics, agriculture,food,biotechnology various differentmarkets.Ourservicesaretailoredfor Eurofins Genomicssuppliesthousandsofcustomersin Customers &Markets and service centres based in Europe, USA, Japan and India. by its 600 highly skilled employees, production facilities Eurofins Genomicshasastrongglobalpresence enforced Global Network more than15,000employees. Scientific Groupwithlaboratoriesacross37countries Founded in1990,EurofinsGenomicsispartofthe permission in writingfromEurofinsGenomics GmbH. means, electronicormechanical, includingphotocopying,recording,orby any informationstorageandretrievalsystem,without © EurofinsGenomicsGmbH, 2014. Allrightsreserved.Nopartofthis brochuremaybereproducedorutilizedinany formorbyany Italy Ireland France Finland Denmark Belgium Austria Toll freephonenumbersinEurope:

800 785950 1800 555056 0800 903807 0800 112 744 8088 1262 0800 77862 0800 296562 achieve optimumresults. difficult samples,wehavetheexpertisetohelpyou and toforensicsamples.Ifyouworkwithextremely pre-paration ofallkindsmaterial,fromfoodtoanimals Our appliedgenomicsdepartmentisrenownedforDNA Superior SamplePreparation professional qualitymanagementprocedure. complete. Theexcellenceofourserviceisoverseenbya Strict confidentialityisguaranteedwitheveryprojectwe Confidentiality • • • • • core businesslines: We offerawide-rangeofgenomicservicesbasedonthe Service Offerings Laboratory Practice(GLP)andGoodClinical(GCP). ISO 17025. We arealsocomplianttotheprinciplesofGood requirements). Furthermoreweareaccreditedaccordingto Next GenerationSequencing Gene Synthesis/MolecularBiology Custom DNASequencing Genotyping /GeneExpression DNA &RNAOligonucleotides UK Switzerland Sweden Norway Netherlands Luxemburg 0800 0323135 0800 562013 020 798148 800 13844 0800 0226215 8002 6418

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