Curriculum Vitae
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Biographical Information
Curriculum Vitae Sharon Hammes-Schiffer Department of Chemistry phone: (203) 432-3915 Yale University 225 Prospect Street e-mail: [email protected] New Haven, CT 06520-8107 http://hammes-schiffer-group.org/ Date of Birth May 27, 1966 Education B.A. Chemistry Princeton University 5/88 summa cum laude, Highest Honors in Chemistry Ph.D. Chemistry Stanford University 9/93 Graduate advisor: Hans C. Andersen Professional Experience John Gamble Kirkwood Professor of Chemistry 1/18 – present Yale University Swanlund Professor of Chemistry 8/12 − 12/17 University of Illinois at Urbana-Champaign Eberly Professor in Biotechnology 8/06 − 8/12 Pennsylvania State University Professor of Chemistry 7/03 − 8/12 Pennsylvania State University Shaffer Associate Professor of Chemistry 8/00 − 7/03 Pennsylvania State University Clare Boothe Luce Assistant Professor of Chemistry 8/95 − 8/00 University of Notre Dame Postdoctoral research scientist AT&T Bell Laboratories 9/93 − 8/95 AT&T Bell Laboratories, Murray Hill, NJ Postdoctoral supervisor: John C. Tully Honors and Awards G. M. Kosolapoff Award from Auburn University, 2019 Member, Connecticut Academy of Science and Engineering (CASE), 2018 Center for Advanced Study Professor, University of Illinois Urbana-Champaign, 2017 Senior Fellow, Canadian Institute for Advanced Research (CIFAR), 2016 − present Fellow, Biophysical Society, 2015 Blue Waters Professor, 2014 – 2018 Member, International Academy of Quantum Molecular Science, 2014 Member, U.S. National Academy of Sciences, 2013 Fellow, American Association for the Advancement of Science, 2013 Member, American Academy of Arts and Sciences, 2012 Fellow, American Chemical Society, 2011 National Institutes of Health MERIT Award, 2011 1 Sharon Hammes-Schiffer CV -- 08/27/18 Fellow, American Physical Society, 2010 American Chemical Society Akron Section Award, 2008 International Academy of Quantum Molecular Science Medal, 2005 Iota Sigma Pi Agnes Fay Morgan Research Award, 2005 Alexander M. -
High-Pressure X-Ray Crystallography and Core Hydrophobicity of T4
HIGH-PRESSURE X-RAY CRYSTALLOGRAPHY AND CORE HYDROPHOBICITY OF T4 LYSOZYMES A Dissertation Presented to the Faculty of the Graduate School of Cornell University in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy by Marcus David Collins January 2006 This document is in the public domain. HIGH-PRESSURE X-RAY CRYSTALLOGRAPHY AND CORE HYDROPHOBICITY OF T4 LYSOZYMES Marcus David Collins, Ph.D. Cornell University 2006 While a great many protein structures are now known, considerably less is known experimentally about how these molecules reversibly fold and unfold into nearly unique, active structures. For more than 50 years, the central hypothesis has been that micro-scale phase separation between oil-like non-polar and charged or po- lar amino acid residues drives the formation of a “hydrophobic” protein core. A great deal of evidence supports this hypothesis, but the unfolding of proteins as a response to pressure contradicts it. A possible solution is the suggestion that pres- sure induced unfolding is a different process from thermally or chemically driven unfolding. Separately, little is known about the structural response of proteins to pressure, although pressure has clear and sometimes large effects on protein activ- ity and stability. For these reasons, we have chosen to study the cavity-containing mutant L99A of T4 Lysozyme, along with the wild-type protein, under pressures up to 2 kbar, a compression of about 0.1%. The protein is remarkably incompress- ible, and the presence of a cavity has almost no impact on the pressure response over the wild-type lysozyme. Instead, four water molecules cooperatively fill the cavity, interacting with each other and the protein roughly equally. -
15/5/40 Liberal Arts and Sciences Chemistry Irwin C. Gunsalus Papers, 1877-1993 BIOGRAPHICAL NOTE Irwin C
15/5/40 Liberal Arts and Sciences Chemistry Irwin C. Gunsalus Papers, 1877-1993 BIOGRAPHICAL NOTE Irwin C. Gunsalus 1912 Born in South Dakota, son of Irwin Clyde and Anna Shea Gunsalus 1935 B.S. in Bacteriology, Cornell University 1937 M.S. in Bacteriology, Cornell University 1940 Ph.D. in Bacteriology, Cornell University 1940-44 Assistant Professor of Bacteriology, Cornell University 1944-46 Associate Professor of Bacteriology, Cornell University 1946-47 Professor of Bacteriology, Cornell University 1947-50 Professor of Bacteriology, Indiana University 1949 John Simon Guggenheim Fellow 1950-55 Professor of Microbiology, University of Illinois 1955-82 Professor of Biochemistry, University of Illinois 1955-66 Head of Division of Biochemistry, University of Illinois 1959 John Simon Guggenheim Fellow 1959-60 Research sabbatical, Institut Edmund de Rothchild, Paris 1962 Patent granted for lipoic acid 1965- Member of National Academy of Sciences 1968 John Simon Guggenheim Fellow 1972-76 Member Levis Faculty Center Board of Directors 1977-78 Research sabbatical, Institut Edmund de Rothchild, Paris 1973-75 President of Levis Faculty Center Board of Directors 1978-81 Chairman of National Academy of Sciences, Section of Biochemistry 1982- Professor of Biochemistry, Emeritus, University of Illinois 1984 Honorary Doctorate, Indiana University 15/5/40 2 Box Contents List Box Contents Box Number Biographical and Personal Biographical Materials, 1967-1995 1 Personal Finances, 1961-65 1-2 Publications, Studies and Reports Journals and Reports, 1955-68 -
Center for History of Physics Newsletter, Spring 2008
One Physics Ellipse, College Park, MD 20740-3843, CENTER FOR HISTORY OF PHYSICS NIELS BOHR LIBRARY & ARCHIVES Tel. 301-209-3165 Vol. XL, Number 1 Spring 2008 AAS Working Group Acts to Preserve Astronomical Heritage By Stephen McCluskey mong the physical sciences, astronomy has a long tradition A of constructing centers of teaching and research–in a word, observatories. The heritage of these centers survives in their physical structures and instruments; in the scientific data recorded in their observing logs, photographic plates, and instrumental records of various kinds; and more commonly in the published and unpublished records of astronomers and of the observatories at which they worked. These records have continuing value for both historical and scientific research. In January 2007 the American Astronomical Society (AAS) formed a working group to develop and disseminate procedures, criteria, and priorities for identifying, designating, and preserving structures, instruments, and records so that they will continue to be available for astronomical and historical research, for the teaching of astronomy, and for outreach to the general public. The scope of this charge is quite broad, encompassing astronomical structures ranging from archaeoastronomical sites to modern observatories; papers of individual astronomers, observatories and professional journals; observing records; and astronomical instruments themselves. Reflecting this wide scope, the members of the working group include historians of astronomy, practicing astronomers and observatory directors, and specialists Oak Ridge National Laboratory; Santa encounters tight security during in astronomical instruments, archives, and archaeology. a wartime visit to Oak Ridge. Many more images recently donated by the Digital Photo Archive, Department of Energy appear on page 13 and The first item on the working group’s agenda was to determine through out this newsletter. -
B I O T E C H I N T H E S U N S H I N E S T A
BIOTECH IN THE SUNSHINE STATE December 2009 American Society for Biochemistry and Molecular Biology ASBMB2011 SPECIAL SYMPOSIA CALL FOR PROPOSALS Partner with the American Society for Biochemistry and Molecular Biology to bring your community together! ASBMB Special Symposia provides you, as a specialized researcher, a unique opportunity to present cutting-edge science mixed with active networking opportunities in an intimate setting. How We’re Different: Format: Majority of talks selected from abstracts, invited speakers, 2-4 days in length Attendee: 60- 200 attendees, including investigators, industry professionals, graduate and postdoctoral students Venues: Unique locations near natural resources that enable time for outdoor recreation and networking opportunities Funding: ASBMB provides initial funding as well as staff support! Learn More About Special Symposia and Proposal Submission Guidelines at www.asbmb.org/meetings Proposals Due March 1, 2010 ATodayFullPageAd_2011_Proposal Submission2.indd 1 11/23/2009 10:50:10 AM contents DECEMBER 2009 On the cover: ASBMB hopes that your holidays are filled with society news lots of serotonin. 2 Letters to the Editor IMAGE: REBECCA HANNA 20 4 President’s Message 7 Washington Update 8 News from the Hill 11 Member Spotlight 12 Retrospective: Mahlon Hoagland (1921-2009) A retrospective 15 Retrospective: on Mahlon Charles Tanford (1921-2009) Hoagland. 12 2010 annual meeting 18 Nobel Laureate Claims the 2010 Herbert Tabor Lectureship 19 Kinase Researcher Named Recipient of FASEB Award special interest 20 Centerpieces: Burnham Institute Touches Down in Orlando departments 26 Education and Training Regulating 30 Minority Affairs transcriptional activity. 32 BioBits 32 34 Career Insights 36 Lipid News resources Scientific Meeting Calendar podcast summary online only Check out the latest ASBMB podcast, in which Journal of Biological Chemistry Associate Editor James N. -
The Hydrodynamic and Conformational Properties of Denatured Proteins in Dilute Solutions
The hydrodynamic and conformational properties of denatured proteins in dilute solutions Guy C. Berry* Department of Chemistry, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213 Received 13 August 2009; Accepted 3 November 2009 DOI: 10.1002/pro.286 Published online 13 November 2009 proteinscience.org Abstract: Published data on the characterization of unfolded proteins in dilute solutions in aqueous guanidine hydrochloride are analyzed to show that the data are not fit by either the random flight or wormlike chain models for linear chains. The analysis includes data on the intrinsic viscosity, root-mean-square radius of gyration, from small-angle X-ray scattering, and hydrodynamic radius, from the translational diffusion coefficient. It is concluded that residual structure consistent with that deduced from nuclear magnetic resonance on these solutions can explain the dilute solution results in a consistent manner through the presence of ring structures, which otherwise have an essentially flexible coil conformation. The ring structures could be in a state of continual flux and rearrangement. Calculation of the radius of gyration for the random- flight model gives a similar reduction of this measure for chains joined at their endpoints, or those containing loop with two dangling ends, each one-fourth the total length of the chain. This relative insensitivity to the details of the ring structure is taken to support the behavior observed across a range of proteins. Keywords: protein; radius of gyration; intrinsic viscosity; loop formation Introduction analysis, with such studies often motivated by inter- In a 2005 article devoted to the discussion of ‘‘the est in the folding of the denatured chain. -
Biographical Information
Curriculum Vitae Sharon Hammes-Schiffer Department of Chemistry phone: (203) 436-3936 Yale University 225 Prospect Street e-mail: [email protected] New Haven, CT 06520-8107 http://hammes-schiffer-group.org/ Date of Birth May 27, 1966 Education B.A. Chemistry Princeton University 5/88 summa cum laude, Highest Honors in Chemistry Ph.D. Chemistry Stanford University 9/93 Graduate advisor: Hans C. Andersen Professional Experience John Gamble Kirkwood Professor of Chemistry 1/18 – present Yale University Swanlund Professor of Chemistry 8/12 − 12/17 University of Illinois at Urbana-Champaign Eberly Professor in Biotechnology 8/06 − 8/12 Pennsylvania State University Professor of Chemistry 7/03 − 8/12 Pennsylvania State University Shaffer Associate Professor of Chemistry 8/00 − 7/03 Pennsylvania State University Clare Boothe Luce Assistant Professor of Chemistry 8/95 − 8/00 University of Notre Dame Postdoctoral research scientist AT&T Bell Laboratories 9/93 − 8/95 AT&T Bell Laboratories, Murray Hill, NJ Postdoctoral supervisor: John C. Tully Honors and Awards American Chemical Society Award in Theoretical Chemistry, 2021 Royal Society of Chemistry Bourke Award, 2020 Joseph O. Hirschfelder Prize in Theoretical Chemistry, 2020-21 Emerson Center Lectureship Award from Emory University, 2020 G. M. Kosolapoff Award from Auburn University, 2019 Honorary Fellow, Chinese Chemical Society, 2018 Member, Connecticut Academy of Science and Engineering (CASE), 2018 Center for Advanced Study Professor, University of Illinois Urbana-Champaign, 2017 Senior Fellow, Canadian Institute for Advanced Research (CIFAR), 2016 − present Fellow, Biophysical Society, 2015 Blue Waters Professor, 2014 – 2018 Member, International Academy of Quantum Molecular Science, 2014 1 Sharon Hammes-Schiffer CV -- 08/24/20 Member, U.S. -
John F. Hartwig Henry Rapoport Professor of Chemistry
John F. Hartwig Henry Rapoport Professor of Chemistry Department of Chemistry, University of California Berkeley 718 Latimer Hall MC# 1460, Berkeley, CA 94720-1460 Email: [email protected] http://www.cchem.berkeley.edu/jfhgrp/ Personal Born August 7, 1964 in Elmhurst, IL Employment 2011-present University of California, Berkeley Henry Rapoport Professor of Chemistry. 2011-present Lawrence Berkeley National Laboratory, Berkeley Senior Faculty Scientist. 2006-2011 University of Illinois Urbana-Champaign Kenneth L. Reinhart Jr. Professor of Chemistry. 2004-2006 Yale University, New Haven, CT Irénée DuPont Professor of Chemistry. 1998-2004 Yale University, New Haven, CT Professor of Chemistry. 1996-1998 Yale University, New Haven, CT Associate Professor of Chemistry. 1992-1996 Yale University, New Haven, CT Assistant Professor of Chemistry. Appointment commenced July 1, 1992. 1990-1992 Massachusetts Institute of Technology, Cambridge, MA American Cancer Society Postdoctoral Associate. 1986-1989 University of California, Berkeley, CA Graduate Student Instructor. Taught organic chemistry to undergraduate students and inorganic chemistry to graduate students. 1985 Monsanto Japan Ltd., Kawachi, Japan Worked among an all-Japanese staff for three months on an agricultural and surface science research project. 1984 General Electric Research and Development, Schenectady, NY Synthesis of novel monomers, ionomers and polymer blends. Education 1990-1992 Massachusetts Institute of Technology, Cambridge, MA Postdoctoral Advisor: Prof. Stephen J. Lippard Studied the Pt-DNA adducts formed by an orally active platinum antitumor drug and the ability of these adducts to block DNA replication and bind cellular proteins. Designed, synthesized, and analyzed a platinum antitumor drug possessing a fluorescent ligand for in vivo monitoring. 1986-1990 University of California, Berkeley, CA Ph.D., Chemistry. -
Charles Phelps Smyth 1895–1990
NATIONAL ACADEMY OF SCIENCES CHARLES PHELPS SMYTH 1 8 9 5 – 1 9 9 0 A Biographical Memoir by BY WALTER KAUZMANN AND JOHN D. ROB ERTS Any opinions expressed in this memoir are those of the authors and do not necessarily reflect the views of the National Academy of Sciences. Biographical Memoir COPYRIGHT 2010 NATIONAL ACADEMY OF SCIENCES WASHINGTON, D.C. CHARLES PHELPS SMYTH February 10, 1895–March 18, 1990 BY WALTER KAUZMANN AND JOHN D . RO B ERTS HARLES PHELPS SMYTH WAS BORN ON FEBRUARY 10, 1895, in CClinton, New York, where his father, Charles Henry Smyth, was a professor of geology and mineralogy at Hamilton College. Princeton President Woodrow Wilson called Charles Henry to Princeton University in 1905. He served on the faculty as a professor of geology until his retirement in 194 and played an important role in building Princeton’s graduate program in geology. At the age of 10 Charles Phelps with his younger brother, Henry D., moved to Princeton. Here the members of the Smyth family—father, mother, and sons—lived out most of their remaining lives. Charlie attended Miss Fine’s School and Lawrenceville before entering Princeton University in the class of 1916. He graduated in chemistry with highest honors (he had been among the first group of students to be admitted to Phi Beta Kappa as juniors), and then stayed on for a year, receiving an M.A. in 1917. During World War I, he served in Washington, first with the Bureau of Standards, then as a first lieutenant in the Chemical Warfare Service. -
View Sourcebook
Alpha Chi Sigma Sourcebook A Repository of Fraternity Knowledge for Reference and Education ACADEMIC YEAR {2021-2022} EDITION ALPHA CHI SIGMA Sourcebook {2021 - 2022} l 1 This Sourcebook is the property of: _________________________________________ ________________________________________ Full Name Chapter Name ___________________________________________________ Pledge Class ___________________________________________________ ___________________________________________________ Date of Pledge Ceremony Date of Initiation ___________________________________________________ ___________________________________________________ Master Alchemist Vice Master Alchemist ___________________________________________________ ___________________________________________________ Master of Ceremonies Reporter ___________________________________________________ ___________________________________________________ Recorder Treasurer ___________________________________________________ ___________________________________________________ Alumni Secretary Other Officer Members of My Pledge Class ________________________________________________________________________________________________________________________ ________________________________________________________________________________________________________________________ ________________________________________________________________________________________________________________________ ________________________________________________________________________________________________________________________ -
Proceedings of the American Philosophical Society Vol. 120, Num
Proceedings of the American Philosophical Society Vol. 120, Num. 1. Año 1976 Held at Philadelphia for Promoting Useful Knowledge Fred L. Whipple. “Comet Kohoutek in Retrospect” Proceedings of the American Philosophical Society. Vol. 120, Num. 1. Año 1976; pagina 1-6 Myron P. Gilmore. “The Berensons and Villa I Tatti” Proceedings of the American Philosophical Society. Vol. 120, Num. 1. Año 1976; pagina 7-12 Helen B. Taussig. “The Development of the Blalock-Taussing Operation and Its Results Twenty Years Later” Proceedings of the American Philosophical Society. Vol. 120, Num. 1. Año 1976; pagina 13-20 Ward H. Goodenough. “On the Origin of Matrilineal Clans: A “Just So” Story” Proceedings of the American Philosophical Society. Vol. 120, Num. 1. Año 1976; pagina 21-36 Leon N. Cooper. “How Possible Becomes Actual in the Quantum Theory” Proceedings of the American Philosophical Society. Vol. 120, Num. 1. Año 1976; pagina 37-45 John Owen King. “Labors of the Estranged Personality: Josiah Royce on “The Case of John Bunyan”” Proceedings of the American Philosophical Society. Vol. 120, Num. 1. Año 1976; pagina 46-58 Stanley A. Czarnik. “The Theory of the Mesolithic in European Archaeology” Proceedings of the American Philosophical Society. Vol. 120, Num. 1. Año 1976; pagina 59-66 Proceedings of the American Philosophical Society Vol. 120, Num. 2. Año 1976 Held at Philadelphia for Promoting Useful Knowledge Jonathan E. Rhoads. “New Approaches in the Study of Neoplasia: Preliminary Remarks for the Symposium” Proceedings of the American Philosophical Society. Vol. 120, Num. 2. Año 1976; pagina 67-68 Sol Spiegelman. “The Search for Viruses in Human Cancer” Proceedings of the American Philosophical Society. -
Aiphistory Newsletter
HISTORY NEWSLETTER One Physics Ellipse CENTER FOR HISTORY OF PHYSICS NEWSLETTER Vol. XXXVII, Number 2 Fall 2005 College Park, MD 20740-3843 AIP Tel. 301-209-3165 Major Changes and Progress in the Project to Document the History of Physicists in Industry (HoPI) ome of the highlights of our continuing study of indus- S trial physicists during the last year include: • The grant-funded project has been extended to the end of 2007. • Orville Butler, an experienced PhD historian of science/business, was hired to replace Tom Lassman who left to accept a career track position. • Staff held site visits at major German industrial archives. • A candidates list for longer oral history interviews is being developed. • Oral history interviews were conducted with 3 major industrial physicists. • All 59 interviews with physicists and R&D managers are transcribed and edited. • We’re well into analysis of the transcripts, using NVivo topical-indexing software. By last fall we had completed site visits at the central R&D laboratories at IBM, Corning, GE, Lucent, Xerox, 3M, Exxon Mobil, Kodak, and Texas Instruments—nine of the fifteen com- panies targeted in the study—and had conducted question-set Henry Anton Erikson demonstrating the properties of liquid air in interviews with 54 corporate physicists and science managers his Department of Physics lecture room, University of Minnesota, and 19 technical librarians, records managers, or archivists em- about 1926. Photo courtesy AIP Emilio Segrè Visual Archives, gift of Susan Kilbride. ployed by the companies. Thus we were well ahead of schedule in laboratory site visits and question-set interviews, but as a result we had fallen behind in editing and analyzing the inter- Grants-in-Aid Serve Variety of Purposes views.