What Are the MOST DANGEROUS E-NUMBERS
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Application A603 Supporting Document 3 FOOD TECHNOLOGY
Application A603 Supporting Document 3 FOOD TECHNOLOGY REPORT Summary The Applicant, Golding Handcrafts, claims that there is a technical need to extend the use of the red food colouring erythrosine in Australia and New Zealand from preserved cherries to food colouring preparations used to colour icing and other cake decorations for the technological purpose of achieving colour enhancement. This has been substantiated with claims that food colourings preparations containing erythrosine possess superior colouring characteristics to alternative red food colourings including colour strength, longevity, lack of bleeding and quality of the finished product. Consequently this allow for a greater range of colouring effects to be achieved including wider ranges of pinks, lavenders, violets, royal blue and true black. The Applicant notes that commercial products are currently available for this purpose in the United States of America (USA) and seeks to import and sell these colourings preparations for cake icing and related products for use in Australia and New Zealand. The merit of using erythrosine is strongly supported by some companies, in particular, AmericolorTM Corporation and CK Products, two of the largest companies who use erythrosine in products for cake decorating purposes. They have advised the Applicant that the purpose of adding erythrosine to food is to achieve a precise visual effect and unique shades which are unattainable by using any other food colours. The colour hue and intensity is directly affected by the amounts of erythrosine added and the proposed amounts are consistent in achieving the intended result – to colour the food. Colour combinations are individually weighed and added to the mix for each single recipe so that a consistent final effect is obtained. -
Artificial Food Colours and Children Why We Want to Limit and Label Foods Containing the ‘Southampton Six’ Food Colours on the UK Market Post-Brexit
Artificial food colours and children Why we want to limit and label foods containing the ‘Southampton Six’ food colours on the UK market post-Brexit November 2020 FIRST STEPS NUTRITIONArtificial food coloursTRUST and children: page Artificial food colours and children: Why we want to limit and label foods containing the‘Southampton Six’ food colours on the UK market post-Brexit November 2020 Published by First Steps Nutrition Trust. A PDF of this resource is available on the First Steps Nutrition Trust website. www.firststepsnutrition.org The text of this resource, can be reproduced in other materials provided that the materials promote public health and make no profit, and an acknowledgement is made to First Steps Nutrition Trust. This resource is provided for information only and individual advice on diet and health should always be sought from appropriate health professionals. First Steps Nutrition Trust Studio 3.04 The Food Exchange New Covent Garden Market London SW8 5EL Registered charity number: 1146408 First Steps Nutrition Trust is a charity which provides evidence-based and independent information and support for good nutrition from pre-conception to five years of age. For more information, see our website: www.firststepsnutrition.org Acknowledgements This report was written by Rachael Wall and Dr Helen Crawley. We would like to thank Annie Seeley, Sarah Weston, Erik Millstone and Anna Rosier for their help and support with this report. Artificial food colours and children: page 1 Contents Page Executive summary 3 Recommendations -
Regulatory Information Sheet
Regulatory Information Sheet Approved Drug Colourants Listed by the European Union Colour Index Colour E Number Alternate Names Number Allura Red AC (a) E129 16035 FD&C Red #40 Aluminum*** E173 77000 -- Amaranth*** (a) E123 16185 Delisted FD&C Red #2 Annatto*** E160b 75120 Bixin, norbixin Anthocyanins (a) E163 -- -- Beetroot Red E162 -- Betanin Beta APO-8´-Carotenal E160e 40820 -- Brilliant Black BN (a) E151 28440 Black BN Brilliant Blue FCF (a) E133 42090 FD&C Blue #1 Brown HT (a) E155 20285 -- Calcium Carbonate E170 77220 -- Canthaxanthin* E161g 40850 -- Caramel,-Plain E150a -- -- Caramel,-Caustic Sulphite E150b -- -- Caramel,-Ammonia E150c -- -- Caramel, Sulphite Ammonia E150d -- -- Carmine (a) E120 75470 Carminic Acid, Cochineal Carmoisine (a) E122 14720 Azorubine Carotenes E160a 40800 / 75130 -- Chlorophylls/Chlorophyllins E140 75810 / 75815 -- Copper Complexes of E141 75815 -- Chlorophylls/Chlorophyllins(a) Curcumin (a) E100 75300 Turmeric Erythrosine*** (a) E127 45430 FD&C Red #3 Gold*** E175 77480 -- Green S (a) E142 44090 Acid Brilliant Green BS Indigotine (a) E132 73015 FD&C Blue #2, Indigo Carmine 77491 / 77492 / Iron Oxides & Hydroxides E172 Iron Oxide Red, Yellow, Black 77499 Litholrubine BK*** (a) E180 -- -- Lutein E161b -- -- Lycopene*** E160d 75125 -- Paprika Extract E160c -- Capsanthin, Capsorubin Patent Blue V (a) E131 42051 Acid Blue 3 Ponceau 4R (a) E124 16255 Cochineal Red A Page 1 of 2 Document Reference No.: GLO-10107, revision 2 Effective Date: September 2014 Reviewed Date: November 2017 This document is valid at the time of distribution. Distributed 24-Sep-2021 (UTC) E Colour Index Colour Alternate Names Number Number Quinoline Yellow** (a) E104 47005 China Yellow Riboflavins (a) E101 -- -- Silver*** E174 -- -- Sunset Yellow FCF (a) E110 15985 FD&C Yellow #6, Orange Yellow S Tartrazine (a) E102 19140 FD&C Yellow #5 Titanium Dioxide E171 77891 -- Vegetable Carbon E153 77268:1 Carbo Medicinalis Vegetalis The above list is derived from Part B, List of All Additives, from Annex II to Regulation (EC) No 1333/2008 on food additives. -
Clean Label Alternatives in Meat Products
foods Review Clean Label Alternatives in Meat Products Gonzalo Delgado-Pando 1 , Sotirios I. Ekonomou 2 , Alexandros C. Stratakos 2 and Tatiana Pintado 1,* 1 Institute of Food Science, Technology and Nutrition (CSIC), José Antonio Novais 10, 28040 Madrid, Spain; [email protected] 2 Centre for Research in Biosciences, Coldharbour Lane, Faculty of Health and Applied Sciences, University of the West of England, Bristol BS16 1QY, UK; [email protected] (S.I.E.); [email protected] (A.C.S.) * Correspondence: [email protected] Abstract: Food authorities have not yet provided a definition for the term “clean label”. However, food producers and consumers frequently use this terminology for food products with few and recognisable ingredients. The meat industry faces important challenges in the development of clean-label meat products, as these contain an important number of functional additives. Nitrites are an essential additive that acts as an antimicrobial and antioxidant in several meat products, making it difficult to find a clean-label alternative with all functionalities. Another important additive not complying with the clean-label requirements are phosphates. Phosphates are essential for the correct development of texture and sensory properties in several meat products. In this review, we address the potential clean-label alternatives to the most common additives in meat products, including antimicrobials, antioxidants, texturisers and colours. Some novel technologies applied for the development of clean label meat products are also covered. Keywords: clean label; meat products; nitrites alternatives; phosphates alternatives Citation: Delgado-Pando, G.; Ekonomou, S.I.; Stratakos, A.C.; Pintado, T. -
Role of Microorganisms in Biodegradation of Food Additive Azo Dyes: a Review
Vol. 19(11), pp.799-805, November, 2020 DOI: 10.5897/AJB2020.17250 Article Number: F63AA1865367 ISSN: 1684-5315 Copyright ©2020 Author(s) retain the copyright of this article African Journal of Biotechnology http://www.academicjournals.org/AJB Review Role of microorganisms in biodegradation of food additive Azo dyes: A review Fatimah Alshehrei Department of Biology, Jamum College University, Umm AlQura University, Makkah24382, Saudi Arabia. Received 22 September, 2020; Accepted 27 October, 2020 Food additives Azo dyes are synthetic compounds added to foods to impart color and improve their properties. Some azo dyes have been banned as food additives due to toxic, mutagenic, and carcinogenic side effects. Long exposure to foods containing azo dye leads to chronic toxicity. Some microorganisms are capable to degrade these dyes and convert them to aromatic amines. In human body, microbiota can play a vital role in biodegradation of azo dyes by producing azo reductase. Aromatic amines are toxic, water-soluble and well absorbed via human intestine. In the current study, the role of microorganisms in biodegradation of six dyes related to azo group was discussed. These dyes are: Tartrazine E102, Sunset Yellow E110, Ponceau E124, Azorubine E122, Amaranth E123, and Allura Red E129 which are classified as the most harmful food additive dyes. Key word: Food additive, azo dyes, microorganisms, azo reductase, aromatic amines. INTRODUCTION Food additives are synthetic compounds added to food In the USA and European countries, some azo dyes have for many proposes such as maintaining the product from been banned as food additives due to toxic, mutagenic, deterioration or improving its safety, freshness, taste, and carcinogenic side effects (Chung, 2000). -
Chemical Basics of Life
© Jones & Bartlett Learning, LLC. NOT FOR SALE OR DISTRIBUTION CHAPTER 2 Chemical Basics of Life OUTLINE KEY TERMS Atoms, Molecules, and Chemical Bonds Acids: Electrolytes that release hydrogen ions in water. Atomic Structure Activation energy: The amount of energy required to start a Molecules reaction. Chemical Bonds Anions: Ions with a negative charge. Types of Chemical Reactions Atomic number: A whole number representing the number Enzymes of positively charged protons in the nucleus of an atom. Acids, Bases, and the pH Scale Atomic weight: The total number of protons and neutrons in Chemical Constituents of Cells the nucleus of an atom. Inorganic Substances Atoms: The smallest complete units of an element, varying in Organic Substances size, weight, and interaction with other atoms. Summary Bases: Electrolytes that release ions that bond with Learning Goals hydrogen ions. Critical Thinking Questions Carbohydrates: Substances (including sugars) that provide Websites much of the energy required by the body’s cells, as well as Review Questions helping to build cell structures. Catalysts: Atoms or molecules that can change the rate of a OBJECTIVES reaction without being consumed during the process. After studying this chapter, readers should be able to: Cations: Ions with a positive charge. 1. Describe the relationships between atoms and Chemistry: The study of the composition of matter and molecules. changes in its composition. 2. Explain chemical bonds. Compounds: Molecules made up of different bonded atoms. 3. Describe how an atomic number is determined. Decomposition: A reaction that occurs when bonds with a 4. List the major groups of inorganic chemicals reactant molecule break, forming simpler atoms, molecules, common in cells. -
Food Additives As Inhibitors of Intestinal Drug Transporter Oatp2b1
1 FOOD ADDITIVES AS INHIBITORS OF INTESTINAL DRUG TRANSPORTER OATP2B1 Alli Tikkanen1, Estelle Pierrot1, Feng Deng1,2, Virginia Barras Sánchez1, Marja Hagström1, Jan B. Koenderink3, Heidi Kidron1* 1Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, P.O. Box 56, 00014 Helsinki, Finland 2 Current address: Department of Clinical Pharmacology, Faculty of Medicine, University of Helsinki 3 Radboud University Medical Center, Department of Pharmacology and Toxicology, Nijmegen, The Netherlands *corresponding author Telephone: +358405666660 Email: [email protected] 2 FOR TABLE OF CONTENTS USE ONLY FOOD ADDITIVES AS INHIBITORS OF INTESTINAL DRUG TRANSPORTER OATP2B1 Alli Tikkanen, Estelle Pierrot, Feng Deng, Virginia Barras Sánchez, Marja Hagström, Jan B. Koenderink, Heidi Kidron 3 ABSTRACT Food additives are compounds that are added to food and beverage to improve taste, color, preservation or composition. Generally, food additives are considered safe for human use due to safety evaluation conducted by food safety authorities and high safety margins applied to permitted usage levels. However, the interaction potential of food additives with simultaneously administered medication has not received much attention. Even though many food additives are poorly absorbed into systemic circulation, high concentrations could exist in the intestinal lumen making intestinal drug transporters, such as the uptake transporter organic anion transporting polypeptide 2B1 (OATP2B1), a possible site of food additive–drug interaction. In the present work, we aimed to characterize the interaction of a selection of 25 food additives including colorants, preservatives and sweeteners with OATP2B1 in vitro. In HEK293 cells transiently overexpressing OATP2B1 or control, uptake of dibromofluorescein was studied with and without 50 µM food additive at pH 7.4. -
An Integrated Approach to Understand Apicomplexan Metabolism From
Shanmugasundram et al. BMC Bioinformatics 2014, 15(Suppl 3):A3 http://www.biomedcentral.com/1471-2105/15/S3/A3 MEETINGABSTRACT Open Access An integrated approach to understand apicomplexan metabolism from their genomes Achchuthan Shanmugasundram1,2*, Faviel F Gonzalez-Galarza1, Jonathan M Wastling2, Olga Vasieva1, Andrew R Jones1 From Ninth International Society for Computational Biology (ISCB) Student Council Symposium 2013 Berlin, Germany. 19 July 2013 Background Methods The Apicomplexa is a large phylum of intracellular para- We have utilised an approach called ‘metabolic recon- sites that show great diversity and adaptability in the struction’, in which genes are systematically assigned to various ecological niches they occupy. They are the cau- functions within pathways/networks [1-4]. Functional sative agents of human and animal infections including annotation and metabolic reconstruction was carried malaria, toxoplasmosis and theileriosis, which have a out using a semi-automatic approach, integrating geno- huge economic and social impact. A number of apicom- mic information with biochemical evidence from the plexan genomes have been sequenced and are publicly literature. The functions were automatically assigned available. However, the prediction of gene models and using a sequence similarity-based approach and protein annotation of gene functions remains challenging. motif information. Experimental evidence was also Table 1 A survey of the data available for the different apicomplexan genomes in LAMP. The analysis is updated from the survey table published in the previous publication [5] Organism No of metabolic No of unique No of missing No of Total no of No of metabolites No of end pathways enzymesa enzymesb reactionsc metabolitesd from hoste metabolites to host or of unknown fatef T. -
The Effect of Using E-Numbers Or Colloquial Additive Names on the Consumption Intention
The effect of using E-numbers or colloquial additive names on the consumption intention. Master thesis Author: Ron Hoogma Supervisor: Arnout Fischer Coreader: Ivo van der Lans Chairgroup: Marketing and Consumer Behaviour Date: 2015 The effect of using E-numbers or colloquial additive names on the consumption intention. Table of content Abstract ................................................................................................................................................... 3 Introduction ............................................................................................................................................. 4 Theoretical background ........................................................................................................................... 6 Risk & Benefit perception .................................................................................................................... 6 Understanding and perceiving additives ............................................................................................. 7 Methodology ......................................................................................................................................... 10 Operationalization ............................................................................................................................. 10 Pre-test .............................................................................................................................................. 11 Main study ........................................................................................................................................ -
Aspartame | European Food Safety Authority
5/17/2017 Aspartame | European Food Safety Authority Home Topics AZ Aspartame Aspartame Aspartame is a lowcalorie, intense artificial sweetener. It is a white, odourless powder, approximately 200 times sweeter than sugar. In Europe, it is authorised to be used as a food additive in foodstuffs such as drinks, desserts, sweets, dairy, chewing gums, energyreducing and weight control products and as a tabletop sweetener. The sweetener aspartame and its breakdown products have been a matter of extensive investigation for more than 30 years including experimental animal studies, clinical research, intake and epidemiological studies and postmarketing surveillance. It has been found to be safe and authorised for human consumption for many years and in many countries following thorough safety assessments. In the European Union (EU) the label on foodstuffs containing aspartame must state its presence, indicating either its name or its E number (E 951). Activities Role EU framework FAQ Completed work Since 2002, EFSA has kept the safety of aspartame under regular review and its Scientific Panels have issued several opinions on studies related to this sweetener. Currently, this work is carried out by the Panel on Food Additives and Nutrient Sources Added to Food (ANS). Latest activities In December 2013 EFSA published its first full risk assessment of aspartame. The opinion concludes that aspartame and its breakdown products are safe for general population (including infants, children and pregnant women). The current Acceptable Daily Intake (ADI) of 40mg/kg bw/day is considered protective for the general population and consumer exposure to aspartame is well below this ADI. -
Food Additives
Food additives Department of Chemistry The Open University of Sri Lanka 1 Published by The Open University of Sri Lanka 2014 Food additives Introduction In previous lessons, we considered the chemistry of synthetic polymers, natural polymers and biomolecules such as carbohydrates, amino acids, proteins, fatty acids and lipids. In this lesson, we intend to study pros and cons of food additives. People around the world use natural and artificial food additives particularly to improve the taste and appearance of food without thinking of their effects on their health. Do you have the practice of checking the list of food additives given in the label when you buy food items? Centuries ago and even today people smoke fish/meat and add certain chemicals to them (e.g. salt) to improve their shelf life. Particularly in eastern countries, people add spices and indigenous herbs to food to improve its taste and colour. Some food varieties are seasonal (and abundant during the season) and are not available throughout the year. But preserved food is made available around the year, enabling us to enjoy food in different forms, even in places where it is not available or produced. Consumption of food additives may have certain health risks. Carcinogenesis (i.e. causation of cancers), hyperactivity in children, precipitation of allergies, and migraine are some known health risks associated with food additives. It is high time you knew more about what you eat. Let us examine the definition of a food additive. Food additives can be defined as chemical substances deliberately added to food, directly or indirectly, in known or regulated quantities, for purposes of assisting in the processing of food, preservation of food, or in improving the flavour, texture, or appearance of food. -
A Novel Approach to Dietary Exposure
Technical stakeholder event, 3 December 2019 A novel approach to dietary exposure Protocol for the exposure assessment as part of the safety assessment of sweeteners under the food additives re-evaluation programme Davide Arcella DATA Unit Sweeteners, to be re-evaluated under Regulation (EC) No 257/2010 E Number Food additive(s) Substance E 420 Sorbitols E 420 (i) Sorbitol E 420(ii) Sorbitol syrup E 421 Mannitols E 421(i) Mannitol by hydrogenation E 421(ii) Mannitol manufactured by fermentation E 950 Acesulfame K E 951(a) Aspartame(a) E 952 Cyclamates E 952(i) Cyclamic acid E 952(ii) Sodium cyclamate E 952(iii) Calcium cyclamate E 953 Isomalt E 954 Saccharin and its Na, K and Ca salts E 954(i) Saccharin E 954(ii) Sodium saccharin E 954(iii) Calcium saccharin E 954(iv) Potassium saccharin E 955 Sucralose E 957 Thaumatin E 959 Neohesperidine dihydrochalcone E 961 Neotame E 962 Salt of aspartame-acesulfame E 965 Maltitols E 965(i) Maltitol E 965(ii) Maltitol syrup E 966 Lactitol E 967 Xylitol 2 E 968 Erythritol Refined exposure assessment of food additives under re-evaluation Dietary exposure assessment Occurrence Consumption Exposure Occurrence data Call for data (batch 7) launched for sweeteners in 2018 (January-October) ▪ Use levels ▪ Analytical results in food and beverages intended for human consumption. From: ▪ National authorities/organisations of the Member States, and ▪ Interested business operators and other parties (e.g. individual food manufacturers, food manufacturer associations, research institutions, academia, food business operators and other stakeholders). An additional call on occurrence data on aspartame (E 951) will be launched to update the assessment of exposure to aspartame (E 951), as well as to assess the total aspartame exposure from the use of the salt of aspartame-acesulfame (E 962) and aspartame (E 951).